Package: spoon Title: Address the Mean-variance Relationship in Spatial Transcriptomics Data Version: 1.9.0 Authors@R: c( person(given = "Kinnary", family = "Shah", role = c("aut", "cre"), email = "kinnaryshahh@gmail.com", comment = c(ORCID = "0000-0001-7098-2116")), person("Boyi", "Guo", email = "boyi.guo.work@gmail.com", role = c("aut"), comment = c(ORCID = "0000-0003-2950-2349")), person("Stephanie C.", "Hicks", email = "shicks19@jhu.edu", role = c("aut"), comment = c(ORCID = "0000-0002-7858-0231"))) Description: This package addresses the mean-variance relationship in spatially resolved transcriptomics data. Precision weights are generated for individual observations using Empirical Bayes techniques. These weights are used to rescale the data and covariates, which are then used as input in spatially variable gene detection tools. URL: https://github.com/kinnaryshah/spoon BugReports: https://github.com/kinnaryshah/spoon/issues Imports: SpatialExperiment, BRISC, nnSVG, BiocParallel, Matrix, methods, SummarizedExperiment, stats, utils, scuttle License: MIT + file LICENSE Encoding: UTF-8 biocViews: Spatial, SingleCell, Transcriptomics, GeneExpression, Preprocessing Depends: R (>= 4.4) Roxygen: list(markdown = TRUE) Suggests: testthat, STexampleData, knitr, rmarkdown, BiocStyle Config/testthat/edition: 3 VignetteBuilder: knitr RoxygenNote: 7.3.2 Config/pak/sysreqs: libmagick++-dev gsfonts libicu-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:02:27 UTC RemoteUrl: https://github.com/bioc/spoon RemoteRef: HEAD RemoteSha: a0a9ed99f574bdca01724cc62f481e9bdea643c6 NeedsCompilation: no Packaged: 2026-07-04 02:59:28 UTC; root Author: Kinnary Shah [aut, cre] (ORCID: ), Boyi Guo [aut] (ORCID: ), Stephanie C. Hicks [aut] (ORCID: ) Maintainer: Kinnary Shah