Package: spillR
Type: Package
Title: Spillover Compensation in Mass Cytometry Data
Version: 1.9.0
Authors@R: c(
    person("Marco", "Guazzini",
    email= "m.guazzini@student.maastrichtuniversity.nl", 
    role = c("aut", "cre"), comment = c(ORCID = "0009-0007-8111-5772")), 
    person("Alexander G.", "Reisach" , 
    email = "alexander.reisach@u-paris.fr", 
    role = "aut", comment = c(ORCID = "0009-0003-5057-6278")),
    person("Sebastian", "Weichwald",
    email = "sweichwald@math.ku.dk", 
    role = "aut", comment = c(ORCID = "0000-0003-0169-7244")), 
    person("Christof", "Seiler", 
    email = "christof.seiler@maastrichtuniversity.nl", 
    role = "aut", comment = c(ORCID = "0000-0001-8802-3642")))
Description: Channel interference in mass cytometry can cause spillover
        and may result in miscounting of protein markers. We develop a
        nonparametric finite mixture model and use the mixture
        components to estimate the probability of spillover. We
        implement our method using expectation-maximization to fit the
        mixture model.
biocViews: FlowCytometry, ImmunoOncology, MassSpectrometry,
        Preprocessing, SingleCell, Software, StatisticalMethod,
        Visualization, Regression
License: LGPL-3
Encoding: UTF-8
Config/testthat/edition: 3
RoxygenNote: 7.3.1
Imports: dplyr, tibble, tidyselect, stats, ggplot2, tidyr,
        spatstat.univar, S4Vectors, parallel
Depends: R (>= 4.3.0), SummarizedExperiment, CATALYST
Suggests: knitr, rmarkdown, cowplot, testthat (>= 3.0.0), BiocStyle,
        hexbin
VignetteBuilder: knitr
Config/pak/sysreqs: cmake libfontconfig1-dev libfreetype6-dev
        libglpk-dev make libicu-dev libpng-dev libxml2-dev libssl-dev
        perl zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 13:02:05 UTC
RemoteUrl: https://github.com/bioc/spillR
RemoteRef: HEAD
RemoteSha: 8db8248296144dbe26d8dfd56d1b1c64298a5723
NeedsCompilation: no
Packaged: 2026-07-03 21:08:52 UTC; root
Author: Marco Guazzini [aut, cre] (ORCID:
    <https://orcid.org/0009-0007-8111-5772>),
  Alexander G. Reisach [aut] (ORCID:
    <https://orcid.org/0009-0003-5057-6278>),
  Sebastian Weichwald [aut] (ORCID:
    <https://orcid.org/0000-0003-0169-7244>),
  Christof Seiler [aut] (ORCID: <https://orcid.org/0000-0001-8802-3642>)
Maintainer: Marco Guazzini <m.guazzini@student.maastrichtuniversity.nl>