Package: speckle Type: Package Title: Statistical methods for analysing single cell RNA-seq data Version: 1.13.0 Date: 2025-10-14 Authors@R: c(person(given = "Belinda", family = "Phipson", role = c("aut", "cre"), email = "phipson.b@wehi.edu.au") ) LazyData: FALSE Depends: R (>= 4.2.0) Imports: limma, edgeR, SingleCellExperiment, Seurat, ggplot2, methods, stats, grDevices, graphics VignetteBuilder: knitr Suggests: BiocStyle, knitr, rmarkdown, statmod, CellBench, scater, patchwork, jsonlite, vdiffr, testthat (>= 3.0.0) Description: The speckle package contains functions for the analysis of single cell RNA-seq data. The speckle package currently contains functions to analyse differences in cell type proportions. There are also functions to estimate the parameters of the Beta distribution based on a given counts matrix, and a function to normalise a counts matrix to the median library size. There are plotting functions to visualise cell type proportions and the mean-variance relationship in cell type proportions and counts. As our research into specialised analyses of single cell data continues we anticipate that the package will be updated with new functions. License: GPL-3 biocViews: SingleCell, RNASeq, Regression, GeneExpression RoxygenNote: 7.2.2 Encoding: UTF-8 Config/testthat/edition: 3 Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:59:31 UTC RemoteUrl: https://github.com/bioc/speckle RemoteRef: HEAD RemoteSha: 784ac53456477b4bc81356029ae9b699f5d1eaf0 NeedsCompilation: no Packaged: 2026-07-03 11:28:39 UTC; root Author: Belinda Phipson [aut, cre] Maintainer: Belinda Phipson