Add 15 new signatures.
Update the evaluationSignPlot
function to return an overall
goodness score.
Add getSignGenes
function to access the signatures gene list.
When multiple signatures are plotted, values are reported in z-scores and not rescaled between 0 and 1 as before.
Add glioCellStateSign
function to compute the glioblastoma
cellular states defined by Neftel C. et al. Cell (2019).
Add whichAssay
argument to signature functions to allow the
user to specify which assay to use for the signature computation.
Users can now plot also other signatures not computed with signifinder when using the heatmapSignPlot, correlationSignPlot and ridgelineSignPlot functions to compare them with the signatures computed with signifinder.
Add evaluationSignPlot
function to show some technical
information of the signatures computed.
Add nametype
argument to geneHeatmapSignPlot
function
to allow more gene name ID in data.
The vignette now contains an example with a single-cell dataset and an example with a spatial transcriptomics dataset.
New package signifinder, for implementation of transcriptional cancer signatures.