Changes in version 2.11.2 o Move VariantAnnotation from Depends to Imports Changes in version 2.11.1 o Remove survivalAnalysis dependency o Fixes for some ggplot2 warnings o Update C++ req to C++14 Changes in version 2.5.1 o Preserve dimnames from the given input matrices Changes in version 2.3.3 o Minor documentation fixes Changes in version 2.3.2 o New function: genCountMatrixFromMAF, to generate a count matrix from a MAF file o support for reading MAF files on signeRFlow o support for utilizing any BSgenome on signeRFlow Changes in version 2.3.1 o Moved the source repository to TojalLab o Fixed issue when running with fixed signatures matrix o Reduced the maxeval time in rare cases when there is no convergence Changes in version 2.1.1 o Fixed doc issues o Fixed cpp issues Changes in version 2.0.0 o interactive shiny interface: signeRFlow o Option to work with previously defined signatures, just estimating exposures. o Parallel processing, o New method to find the number of signatures (or groups) present in data, based on statistical testes of BIC values, o Tests of signature association with survival data or continuous variables, o Exposure-based clustering methods Changes in version 1.19.1 o migrate to PMCMRplus package Changes in version 1.13.1 o fix issue with pseudo-variants on vcf Changes in version 1.11.1 o ignore mutations on edges of chromosomes Changes in version 1.9.3 o fix parsing issue in genCountMatrixFromVcf for some vcfs Changes in version 1.9.2 o fix for genCountMatrixFromVcf fails with phased genotypes o added one-vcf-per-sample example to vignette Changes in version 1.9.1 o fix prototype mismatch issue o fix plot error: non-finite ylim when pvalue=0 Changes in version 1.7.1 o optimization of genCountMatrixFromVcf function Changes in version 1.5.2 o support for generating matrices with a DNAStringSet Changes in version 1.5.1 o fix GRanges list usage o fix conflicts of NMF:seed, by adding VariantAnnotation to Depends before NMF Changes in version 1.1.7 o Reorder method was renamed to Reorder_signatures. o New methods Reorder_samples and Reorder_mutations was added. Changes in version 1.1.2 o Pre-calculate plot data during object construction Changes in version 1.0.0 o First Bioconductor release. Changes in version 0.99.17 o Reduced memory usage.