# -------------------------------------------- # CITATION file created with {cffr} R package # See also: https://docs.ropensci.org/cffr/ # -------------------------------------------- cff-version: 1.2.0 message: 'To cite package "seq2pathway" in publications use:' type: software license: GPL-2.0-only title: 'seq2pathway: a novel tool for functional gene-set (or termed as pathway) analysis of next-generation sequencing data' version: 1.37.0 abstract: Seq2pathway is a novel tool for functional gene-set (or termed as pathway) analysis of next-generation sequencing data, consisting of "seq2gene" and "gene2path" components. The seq2gene links sequence-level measurements of genomic regions (including SNPs or point mutation coordinates) to gene-level scores, and the gene2pathway summarizes gene scores to pathway-scores for each sample. The seq2gene has the feasibility to assign both coding and non-exon regions to a broader range of neighboring genes than only the nearest one, thus facilitating the study of functional non-coding regions. The gene2pathway takes into account the quantity of significance for gene members within a pathway compared those outside a pathway. The output of seq2pathway is a general structure of quantitative pathway-level scores, thus allowing one to functional interpret such datasets as RNA-seq, ChIP-seq, GWAS, and derived from other next generational sequencing experiments. authors: - family-names: Kinstlick given-names: Arjun email: akinstlick@uchicago.edu - email: binw@uchicago.edu repository: https://bioc.r-universe.dev date-released: '2021-11-21' contact: - family-names: Kinstlick given-names: Arjun email: akinstlick@uchicago.edu