# --------------------------------------------
# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
# --------------------------------------------
 
cff-version: 1.2.0
message: 'To cite package "seq.hotSPOT" in publications use:'
type: software
license: Artistic-2.0
title: 'seq.hotSPOT: Targeted sequencing panel design based on mutation hotspots'
version: 1.5.0
abstract: seq.hotSPOT provides a resource for designing effective sequencing panels
  to help improve mutation capture efficacy for ultradeep sequencing projects. Using
  SNV datasets, this package designs custom panels for any tissue of interest and
  identify the genomic regions likely to contain the most mutations. Establishing
  efficient targeted sequencing panels can allow researchers to study mutation burden
  in tissues at high depth without the economic burden of whole-exome or whole-genome
  sequencing. This tool was developed to make high-depth sequencing panels to study
  low-frequency clonal mutations in clinically normal and cancerous tissues.
authors:
- family-names: Grant
  given-names: Sydney
  email: sydney.grant@roswellpark.org
- family-names: Wei
  given-names: Lei
  email: lei.wei@roswellpark.org
- family-names: Paragh
  given-names: Gyorgy
  email: gyorgy.paragh@roswellpark.org
repository: https://bioc.r-universe.dev
repository-code: https://github.com/sydney-grant/seq.hotSPOT
url: https://github.com/sydney-grant/seq.hotSPOT
contact:
- family-names: Grant
  given-names: Sydney
  email: sydney.grant@roswellpark.org