Package: sccomp Type: Package Title: Differential Composition and Variability Analysis for Single-Cell Data Version: 2.5.0 Date: 2024-01-15 Authors@R: c(person("Stefano", "Mangiola", email = "stefano.mangiola@unimelb.edu.au", role = c("aut", "cre")), person("Alexandra J.", "Roth-Schulze", role = "aut"), person("Marie", "Trussart", role = "aut"), person("Enrique", "Zozaya-Valdés", role = "aut"), person("Mengyao", "Ma", role = "aut"), person("Zijie", "Gao", role = "aut"), person("Alan F.", "Rubin", role = "aut"), person("Terence P.", "Speed", role = "aut"), person("Heejung", "Shim", role = "aut"), person("Anthony T.", "Papenfuss", role = "aut")) Description: Comprehensive R package for differential composition and variability analysis in single-cell RNA sequencing, CyTOF, and microbiome data. Provides robust Bayesian modeling with outlier detection, random effects, and advanced statistical methods for cell type proportion analysis. Features include probabilistic outlier identification, mixed-effect modeling, differential variability testing, and comprehensive visualization tools. Perfect for cancer research, immunology, developmental biology, and single-cell genomics applications. License: GPL-3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 Depends: R (>= 4.3.0), instantiate (>= 0.2.3) Imports: stats, boot, utils, scales, lifecycle, rlang, tidyselect, magrittr, crayon, cli, fansi, dplyr, tidyr, purrr, tibble, ggplot2, ggrepel, patchwork, forcats, readr, stringr, glue, SingleCellExperiment Suggests: knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0), markdown, loo, prettydoc, SeuratObject, tidyseurat, tidySingleCellExperiment, bayesplot, posterior Additional_repositories: https://mc-stan.org/r-packages/ SystemRequirements: CmdStan (https://mc-stan.org/users/interfaces/cmdstan), C++14 biocViews: Bayesian, Regression, DifferentialExpression, SingleCell, Metagenomics, FlowCytometry, Spatial LazyData: true VignetteBuilder: knitr URL: https://github.com/MangiolaLaboratory/sccomp BugReports: https://github.com/MangiolaLaboratory/sccomp/issues Config/testthat/edition: 3 Config/testthat/parallel: true Config/testthat/snapshot/parallel: true Config/testthat/snapshot/parallel/workers: 2 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:57:30 UTC RemoteUrl: https://github.com/bioc/sccomp RemoteRef: HEAD RemoteSha: 67110133c81134c0eea020eab7b916279ce23187 NeedsCompilation: no Packaged: 2026-06-15 07:40:45 UTC; root Author: Stefano Mangiola [aut, cre], Alexandra J. Roth-Schulze [aut], Marie Trussart [aut], Enrique Zozaya-Valdés [aut], Mengyao Ma [aut], Zijie Gao [aut], Alan F. Rubin [aut], Terence P. Speed [aut], Heejung Shim [aut], Anthony T. Papenfuss [aut] Maintainer: Stefano Mangiola