Package: sccomp Type: Package Title: Differential Composition and Variability Analysis for Single-Cell Data Version: 2.5.0 Date: 2026-05-11 Authors@R: c(person("Stefano", "Mangiola", email = "stefano.mangiola@unimelb.edu.au", role = c("aut", "cre")), person("Alexandra J.", "Roth-Schulze", role = "aut"), person("Marie", "Trussart", role = "aut"), person("Enrique", "Zozaya-Valdés", role = "aut"), person("Mengyao", "Ma", role = "aut"), person("Zijie", "Gao", role = "aut"), person("Alan F.", "Rubin", role = "aut"), person("Terence P.", "Speed", role = "aut"), person("Heejung", "Shim", role = "aut"), person("Anthony T.", "Papenfuss", role = "aut")) Description: Comprehensive R package for differential composition and variability analysis in single-cell RNA sequencing, CyTOF, and microbiome data. Provides robust Bayesian modeling with outlier detection, random effects, and advanced statistical methods for cell type proportion analysis. Features include probabilistic outlier identification, mixed-effect modeling, differential variability testing, and comprehensive visualization tools. Perfect for cancer research, immunology, developmental biology, and single-cell genomics applications. License: GPL-3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) Depends: R (>= 4.3.0), instantiate (>= 0.2.3) Imports: stats, boot, utils, scales, lifecycle, rlang, tidyselect, magrittr, crayon, cli, fansi, dplyr, tidyr, purrr, tibble, ggplot2, ggrepel, ggside, patchwork, forcats, readr, stringr, glue, SingleCellExperiment, posterior Suggests: mgcv, knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0), markdown, loo, prettydoc, SeuratObject, tidyseurat, tidySingleCellExperiment, bayesplot, remotes Additional_repositories: https://mc-stan.org/r-packages/ SystemRequirements: CmdStan (https://mc-stan.org/users/interfaces/cmdstan), C++14 biocViews: Bayesian, Regression, DifferentialExpression, SingleCell, Metagenomics, FlowCytometry, Spatial LazyData: true VignetteBuilder: knitr URL: https://github.com/MangiolaLaboratory/sccomp, https://mangiolalaboratory.github.io/sccomp/ BugReports: https://github.com/MangiolaLaboratory/sccomp/issues Config/testthat/edition: 3 Config/testthat/parallel: false Config/testthat/snapshot/parallel: false Config/testthat/snapshot/parallel/workers: 2 Config/roxygen2/version: 8.0.0 Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-08-07 01:28:00 UTC RemoteUrl: https://github.com/bioc/sccomp RemoteRef: HEAD RemoteSha: 99257304418fcbd70fa33357549b00cfddd2df7a NeedsCompilation: no Packaged: 2026-10-06 09:04:30 UTC; root Author: Stefano Mangiola [aut, cre], Alexandra J. Roth-Schulze [aut], Marie Trussart [aut], Enrique Zozaya-Valdés [aut], Mengyao Ma [aut], Zijie Gao [aut], Alan F. Rubin [aut], Terence P. Speed [aut], Heejung Shim [aut], Anthony T. Papenfuss [aut] Maintainer: Stefano Mangiola