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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "scDesign3" in publications use:'
type: software
license: MIT
title: 'scDesign3: A unified framework of realistic in silico data generation and
  statistical model inference for single-cell and spatial omics'
version: 1.3.0
doi: 10.1038/s41587-023-01772-1
identifiers:
- type: doi
  value: 10.32614/CRAN.package.scDesign3
abstract: We present a statistical simulator, scDesign3, to generate realistic single-cell
  and spatial omics data, including various cell states, experimental designs, and
  feature modalities, by learning interpretable parameters from real data. Using a
  unified probabilistic model for single-cell and spatial omics data, scDesign3 infers
  biologically meaningful parameters; assesses the goodness-of-fit of inferred cell
  clusters, trajectories, and spatial locations; and generates in silico negative
  and positive controls for benchmarking computational tools.
authors:
- family-names: Song
  given-names: Dongyuan
  email: dongyuansong@ucla.edu
  orcid: https://orcid.org/0000-0003-1114-1215
- family-names: Wang
  given-names: Qingyang
  email: qw802@g.ucla.edu
  orcid: https://orcid.org/0000-0002-1051-609X
preferred-citation:
  type: article
  title: scDesign3 generates realistic in silico data for multimodal single-cell and
    spatial omics
  authors:
  - name: Song
  - name: Dongyuan
  - name: Wang
  - name: Qingyang
  - name: Yan
  - name: Guanao
  - name: Liu
  - name: Tianyang
  - name: Sun
  - name: Tianyi
  - name: Li
  - family-names: Jessica
    given-names: Jingyi
  journal: Nature Biotechnology
  year: '2023'
  publisher:
    name: Nature Publishing Group US New York
  doi: 10.1038/s41587-023-01772-1
repository: https://bioc.r-universe.dev
repository-code: https://github.com/SONGDONGYUAN1994/scDesign3
commit: 1d45f65cc35c686fb89201b137835866ceb0dcca
url: https://github.com/SONGDONGYUAN1994/scDesign3
contact:
- family-names: Song
  given-names: Dongyuan
  email: dongyuansong@ucla.edu
  orcid: https://orcid.org/0000-0003-1114-1215