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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "sSeq" in publications use:'
type: software
license: GPL-3.0-or-later
title: 'sSeq: Shrinkage estimation of dispersion in Negative Binomial models for RNA-seq
  experiments with small sample size'
version: 1.43.0
doi: 10.32614/CRAN.package.sSeq
abstract: The purpose of this package is to discover the genes that are differentially
  expressed between two conditions in RNA-seq experiments. Gene expression is measured
  in counts of transcripts and modeled with the Negative Binomial (NB) distribution
  using a shrinkage approach for dispersion estimation. The method of moment (MM)
  estimates for dispersion are shrunk towards an estimated target, which minimizes
  the average squared difference between the shrinkage estimates and the initial estimates.
  The exact per-gene probability under the NB model is calculated, and used to test
  the hypothesis that the expected expression of a gene in two conditions identically
  follow a NB distribution.
authors:
- family-names: Yu
  given-names: Danni
  email: dyu@purdue.edu
- family-names: Huber
  given-names: Wolfgang
  email: whuber@embl.de
- family-names: Vitek
  given-names: Olga
  email: ovitek@purdue.edu
repository: https://bioc.r-universe.dev
commit: 48a8461c6b9f3294c64ffb94a617628ea46299dc
date-released: '2013-04-17'
contact:
- family-names: Yu
  given-names: Danni
  email: dyu@purdue.edu