Package: sSNAPPY Title: Single Sample directioNAl Pathway Perturbation analYsis Version: 1.17.0 Authors@R: c( person( "Wenjun", "Liu", , "wenjun.liu@adelaide.edu.au", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-8185-3069")), person( "Stephen", "Pederson", email = "stephen.pederson.au@gmail.com", role = "aut", comment = c(ORCID = "0000-0001-8197-3303"))) Description: A single sample pathway perturbation testing method for RNA-seq data. The method propagates changes in gene expression down gene-set topologies to compute single-sample directional pathway perturbation scores that reflect potential direction of change. Perturbation scores can be used to test significance of pathway perturbation at both individual-sample and treatment levels. License: GPL-3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.3 Suggests: BiocManager, BiocStyle, colorspace, cowplot, DT, htmltools, knitr, pander, patchwork, rmarkdown, spelling, testthat (>= 3.0.0), tidyverse Config/testthat/edition: 3 SystemRequirements: C++11 LazyData: false Imports: dplyr (>= 1.1), magrittr, rlang, stats, graphite, tibble, ggraph, igraph, reshape2, org.Hs.eg.db, SummarizedExperiment, edgeR, methods, ggforce, pheatmap, utils, stringr, gtools, tidyr Depends: R (>= 4.3.0), ggplot2 biocViews: Software, GeneExpression, GeneSetEnrichment, GeneSignaling URL: https://wenjun-liu.github.io/sSNAPPY/ VignetteBuilder: knitr BugReports: https://github.com/Wenjun-Liu/sSNAPPY/issues Language: en-US Config/pak/sysreqs: libfontconfig1-dev libfreetype6-dev libglpk-dev libicu-dev libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:58:16 UTC RemoteUrl: https://github.com/bioc/sSNAPPY RemoteRef: HEAD RemoteSha: 6d1ae1b5896745d0d375696f7147d9da607b0b94 NeedsCompilation: no Packaged: 2026-07-09 07:00:56 UTC; root Author: Wenjun Liu [aut, cre] (ORCID: ), Stephen Pederson [aut] (ORCID: ) Maintainer: Wenjun Liu