Package: rmspc Type: Package Title: Multiple Sample Peak Calling Version: 1.19.0 Authors@R: c(person("Vahid", "Jalili", role = "aut", email = "jalili.vahid@gmail.com"), person("Marzia Angela", "Cremona", role = "aut", email = "marzia.cremona@fsa.ulaval.ca"), person("Fernando", "Palluzzi", role = "aut", email = "fernando.palluzzi@gmail.com"), person("Meriem", "Bahda", role = c("aut","cre"), email = "meriembahda@gmail.com")) Imports: processx, BiocManager, rtracklayer, stats, tools, methods, GenomicRanges, stringr Suggests: knitr, rmarkdown, BiocStyle, testthat (>= 3.0.0) VignetteBuilder: knitr Description: The rmspc package runs MSPC (Multiple Sample Peak Calling) software using R. The analysis of ChIP-seq samples outputs a number of enriched regions (commonly known as "peaks"), each indicating a protein-DNA interaction or a specific chromatin modification. When replicate samples are analyzed, overlapping peaks are expected. This repeated evidence can therefore be used to locally lower the minimum significance required to accept a peak. MSPC uses combined evidence from replicated experiments to evaluate peak calling output, rescuing peaks, and reduce false positives. It takes any number of replicates as input and improves sensitivity and specificity of peak calling on each, and identifies consensus regions between the input samples. biocViews: ChIPSeq, Sequencing, ChipOnChip, DataImport, RNASeq License: GPL-3 Encoding: UTF-8 URL: https://genometric.github.io/MSPC/ BugReports: https://github.com/Genometric/MSPC/issues SystemRequirements: .NET 9.0 RoxygenNote: 7.1.1 Config/testthat/edition: 3 Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:56:45 UTC RemoteUrl: https://github.com/bioc/rmspc RemoteRef: HEAD RemoteSha: fc2aff8e026bf3e47047f5dc019b9b76aec37ea2 NeedsCompilation: no Packaged: 2026-07-18 08:42:12 UTC; root Author: Vahid Jalili [aut], Marzia Angela Cremona [aut], Fernando Palluzzi [aut], Meriem Bahda [aut, cre] Maintainer: Meriem Bahda