Package: ramr Title: Detection of Rare Aberrantly Methylated Regions in Array and NGS Data Version: 1.21.0 Authors@R: person(given = "Oleksii", family = "Nikolaienko", role = c("aut", "cre"), email = "oleksii.nikolaienko@gmail.com", comment = c(ORCID = "0000-0002-5910-4934")) Description: ramr is an R package for detection of epimutations (i.e., infrequent aberrant DNA methylation events) in large data sets obtained by methylation profiling using array or high-throughput methylation sequencing. In addition, package provides functions to visualize found aberrantly methylated regions (AMRs), to generate sets of all possible regions to be used as reference sets for enrichment analysis, and to generate biologically relevant test data sets for performance evaluation of AMR/DMR search algorithms. SystemRequirements: C++20, GNU make NeedsCompilation: yes Depends: R (>= 4.1) Imports: methods, data.table, Seqinfo, GenomicRanges, IRanges, BiocGenerics, S4Vectors, Rcpp LinkingTo: Rcpp Suggests: RUnit, knitr, rmarkdown, ggplot2, gridExtra, annotatr, LOLA, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene, parallel, doParallel, foreach, doRNG, matrixStats, EnvStats, ExtDist, gamlss, gamlss.dist License: Artistic-2.0 URL: https://github.com/BBCG/ramr BugReports: https://github.com/BBCG/ramr/issues Encoding: UTF-8 biocViews: DNAMethylation, DifferentialMethylation, Epigenetics, MethylationArray, MethylSeq RoxygenNote: 7.3.3 VignetteBuilder: knitr Config/pak/sysreqs: make Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:54:43 UTC RemoteUrl: https://github.com/bioc/ramr RemoteRef: HEAD RemoteSha: 637945ec82faa42950f5e14aaa8ecfd60c57ec4b Packaged: 2026-07-04 16:56:06 UTC; root Author: Oleksii Nikolaienko [aut, cre] (ORCID: ) Maintainer: Oleksii Nikolaienko