Package: rGREAT Type: Package Title: GREAT Analysis - Functional Enrichment on Genomic Regions Version: 2.15.0 Date: 2026-01-30 Authors@R: person("Zuguang", "Gu", email = "guzuguang@suat-sz.edu.cn", role = c("aut", "cre"), comment = c('ORCID'="0000-0002-7395-8709")) Depends: R (>= 4.0.0), GenomicRanges, IRanges, methods Imports: graphics, rjson, GetoptLong (>= 0.0.9), RCurl, utils, stats, GlobalOptions, shiny, DT, GenomicFeatures, digest, GO.db, progress, circlize, AnnotationDbi, TxDb.Hsapiens.UCSC.hg19.knownGene, TxDb.Hsapiens.UCSC.hg38.knownGene, org.Hs.eg.db, RColorBrewer, S4Vectors, GenomeInfoDb, foreach, doParallel, Rcpp Suggests: testthat (>= 0.3), knitr, rmarkdown, BiocManager, org.Mm.eg.db, msigdbr, KEGGREST, reactome.db Enhances: BioMartGOGeneSets, UniProtKeywords VignetteBuilder: knitr biocViews: GeneSetEnrichment, GO, Pathways, Software, Sequencing, WholeGenome, GenomeAnnotation, Coverage Description: GREAT (Genomic Regions Enrichment of Annotations Tool) is a type of functional enrichment analysis directly performed on genomic regions. This package implements the GREAT algorithm (the local GREAT analysis), also it supports directly interacting with the GREAT web service (the online GREAT analysis). Both analysis can be viewed by a Shiny application. rGREAT by default supports more than 600 organisms and a large number of gene set collections, as well as self-provided gene sets and organisms from users. Additionally, it implements a general method for dealing with background regions. URL: https://github.com/jokergoo/rGREAT, http://great.stanford.edu/public/html/ License: MIT + file LICENSE LinkingTo: Rcpp Config/pak/sysreqs: cmake make libbz2-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev perl xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:40:34 UTC RemoteUrl: https://github.com/bioc/rGREAT RemoteRef: HEAD RemoteSha: 108d370ebb1557cb403384c46b6990009de1b56b NeedsCompilation: yes Packaged: 2026-06-23 20:33:44 UTC; root Author: Zuguang Gu [aut, cre] (ORCID: ) Maintainer: Zuguang Gu