Package: quantiseqr Title: Quantification of the Tumor Immune contexture from RNA-seq data Version: 1.21.0 Authors@R: c( person( given = "Federico", family = "Marini", role = c("aut", "cre"), email = "marinif@uni-mainz.de", comment = c(ORCID = "0000-0003-3252-7758") ), person( given = "Francesca", family = "Finotello", role = "aut", email = "francesca.finotello@i-med.ac.at", comment = c(ORCID = "0000-0003-0712-4658") ) ) Description: This package provides a streamlined workflow for the quanTIseq method, developed to perform the quantification of the Tumor Immune contexture from RNA-seq data. The quantification is performed against the TIL10 signature (dissecting the contributions of ten immune cell types), carefully crafted from a collection of human RNA-seq samples. The TIL10 signature has been extensively validated using simulated, flow cytometry, and immunohistochemistry data. License: GPL-3 Depends: R (>= 4.1.0) Imports: Biobase, limSolve, MASS, methods, preprocessCore, stats, SummarizedExperiment, ggplot2, tidyr, rlang, utils Suggests: AnnotationDbi, BiocStyle, dplyr, ExperimentHub, GEOquery, knitr, macrophage, org.Hs.eg.db, reshape2, rmarkdown, testthat, tibble biocViews: GeneExpression, Software, Transcription, Transcriptomics, Sequencing, Microarray, Visualization, Annotation, ImmunoOncology, FeatureExtraction, Classification, StatisticalMethod, ExperimentHubSoftware, FlowCytometry VignetteBuilder: knitr Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.2 Config/pak/sysreqs: libicu-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:55:53 UTC RemoteUrl: https://github.com/bioc/quantiseqr RemoteRef: HEAD RemoteSha: 983dfb45626f28d2da5fc52e8a128d98fcebad04 NeedsCompilation: no Packaged: 2026-07-03 05:45:18 UTC; root Author: Federico Marini [aut, cre] (ORCID: ), Francesca Finotello [aut] (ORCID: ) Maintainer: Federico Marini