Package: prolfqua Type: Package Title: Proteomics Label Free Quantification Version: 0.99.3 Authors@R: c( person("Witold", "Wolski", email = "witold.wolski@fgcz.uzh.ch", role = "aut", comment = c(ORCID = "0000-0002-6468-120X")), person("Functional Genomics Center Zurich", role = "fnd"), person("Christian", "Panse", email = "cp@fgcz.ethz.ch", role = "cre", comment = c(ORCID = "0000-0003-1975-3064"))) Description: The prolfqua package integrates essential steps of the mass spectrometry based label free quantification data analysis workflow: quality control, data normalization, protein aggregation, modeling, hypothesis testing and sample size estimation. We use prolfqua to : develop highly customizable, visually appealing, and interactive data analysis reports in pdf or HTML format; to visualize and model simple experimental designs with a single explanatory variable and complex experiments with multiple factors; to benchmark data acquisition, data preprocessing or data modeling methods. We developed and improved the package by applying the "Eating your own dog food" principle, when analysing dozens of proteomics datasets. License: MIT + file LICENSE Encoding: UTF-8 VignetteBuilder: knitr URL: https://github.com/fgcz/prolfqua, https://fgcz.github.io/prolfqua/ BugReports: https://github.com/fgcz/prolfqua/issues Imports: circlize, ComplexHeatmap, dplyr, forcats, ggplot2, ggbeeswarm, ggrepel, limma, lme4, lmerTest, logistf, MASS, methods, plotly, progress, purrr, rlang, stringi, tidyselect, tidyr, tibble, UpSetR, withr Suggests: BiocCheck, BiocStyle, corrplot, covr, crosstalk, cyclocomp, devtools, goodpractice, gridExtra, KernSmooth, knitr, limpa, lintr, pkgdown, preprocessCore, rcmdcheck, Rfit, rmarkdown, roxygen2, S4Vectors, SummarizedExperiment, testthat, vsn RoxygenNote: 7.3.3 Roxygen: list(r6 = TRUE) Depends: R (>= 4.5) biocViews: MassSpectrometry, Proteomics, Metabolomics, Normalization, Preprocessing, QualityControl Config/pak/sysreqs: cmake make libicu-dev libpng-dev libuv1-dev libssl-dev perl libx11-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-23 08:07:47 UTC RemoteUrl: https://github.com/bioc/prolfqua RemoteRef: HEAD RemoteSha: 0726bc3c1001b999013bee2174ba3a46dd90edb9 NeedsCompilation: no Packaged: 2026-10-23 13:47:51 UTC; root Author: Witold Wolski [aut] (ORCID: ), Functional Genomics Center Zurich [fnd], Christian Panse [cre] (ORCID: ) Maintainer: Christian Panse