Package: progeny Title: Pathway RespOnsive GENes for activity inference from gene expression Version: 1.35.0 Authors@R: c( person(given = "Michael", family = "Schubert", role = "aut"), person(given = "Alberto", family = "Valdeolivas", role = "ctb", email = "alvaldeolivas@gmail.com", comment = c(ORCID = "0000-0001-5482-9023")), person(given = "Christian H.", family = "Holland", role = "ctb", email = "cholland2408@gmail.com", comment = c(ORCID = "0000-0002-3060-5786")), person(given = "Igor", family = "Bulanov", role = "ctb"), person(given = "Aurélien", family = "Dugourd", role = c("cre","ctb"), email = "aurelien.dugourd@bioquant.uni-heidelberg.de") ) Description: PROGENy is resource that leverages a large compendium of publicly available signaling perturbation experiments to yield a common core of pathway responsive genes for human and mouse. These, coupled with any statistical method, can be used to infer pathway activities from bulk or single-cell transcriptomics. URL: https://github.com/saezlab/progeny BugReports: https://github.com/saezlab/progeny/issues Depends: R (>= 3.6.0) Imports: Biobase, stats, dplyr, tidyr, ggplot2, ggrepel, gridExtra, decoupleR, reshape2 biocViews: SystemsBiology, GeneExpression, FunctionalPrediction, GeneRegulation License: Apache License (== 2.0) | file LICENSE LazyData: true LazyDataCompression: bzip2 Encoding: UTF-8 Suggests: airway, biomaRt, BiocFileCache, broom, Seurat, SingleCellExperiment, DESeq2, BiocStyle, knitr, readr, readxl, pheatmap, tibble, rmarkdown, testthat (>= 2.1.0) VignetteBuilder: knitr RoxygenNote: 7.1.2 Config/pak/sysreqs: libicu-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:46:41 UTC RemoteUrl: https://github.com/bioc/progeny RemoteRef: HEAD RemoteSha: 9779c69771093ae4f39373fdff63eb788473c134 NeedsCompilation: no Packaged: 2026-07-04 12:36:36 UTC; root Author: Michael Schubert [aut], Alberto Valdeolivas [ctb] (ORCID: ), Christian H. Holland [ctb] (ORCID: ), Igor Bulanov [ctb], Aurélien Dugourd [cre, ctb] Maintainer: Aurélien Dugourd