Package: proDA Type: Package Title: Differential Abundance Analysis of Label-Free Mass Spectrometry Data Version: 1.27.0 Authors@R: c(person("Constantin", "Ahlmann-Eltze", email = "artjom31415@googlemail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-3762-068X")), person("Simon", "Anders", email="s.anders@zmbh.uni-heidelberg.de", role="ths", comment = c(ORCID = "0000-0003-4868-1805"))) Description: Account for missing values in label-free mass spectrometry data without imputation. The package implements a probabilistic dropout model that ensures that the information from observed and missing values are properly combined. It adds empirical Bayesian priors to increase power to detect differentially abundant proteins. License: GPL-3 Encoding: UTF-8 RoxygenNote: 7.1.0 Suggests: testthat (>= 2.1.0), MSnbase, dplyr, stringr, readr, tidyr, tibble, limma, numDeriv, pheatmap, knitr, rmarkdown, BiocStyle Imports: stats, utils, methods, BiocGenerics, SummarizedExperiment, S4Vectors, extraDistr URL: https://github.com/const-ae/proDA BugReports: https://github.com/const-ae/proDA/issues biocViews: Proteomics, MassSpectrometry, DifferentialExpression, Bayesian, Regression, Software, Normalization, QualityControl VignetteBuilder: knitr Config/pak/sysreqs: zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:50:37 UTC RemoteUrl: https://github.com/bioc/proDA RemoteRef: HEAD RemoteSha: ae2d3b17498a68ebd3a5a29e4e5afa4bd2883134 NeedsCompilation: no Packaged: 2026-07-04 23:30:30 UTC; root Author: Constantin Ahlmann-Eltze [aut, cre] (ORCID: ), Simon Anders [ths] (ORCID: ) Maintainer: Constantin Ahlmann-Eltze