Package: phenomis Type: Package Title: Postprocessing and univariate analysis of omics data Version: 1.15.0 Date: 2024-09-02 Authors@R: c( person(given = "Etienne A.", family = "Thevenot", email = "etienne.thevenot@cea.fr", role = c("aut", "cre"), comment = c(ORCID = "0000-0003-1019-4577")), person(given = "Natacha", family = "Lenuzza", email = "n.lenuzza@gmail.com", role = "ctb"), person(given = "Marie", family = "Tremblay-Franco", email = "marie.tremblay-franco@inrae.fr", role = "ctb"), person(given = "Alyssa", family = "Imbert", email = "alyssa.imbert@gmail.com", role = "ctb"), person(given = "Pierrick", family = "Roger", email = "pierrick.roger@cea.fr", role = "ctb"), person(given = "Eric", family = "Venot", email = "eric.venot@cea.fr", role = "ctb"), person(given = "Sylvain", family = "Dechaumet", email = "sylvain.dechaumet@cea.fr", role = "ctb") ) Description: The 'phenomis' package provides methods to perform post-processing (i.e. quality control and normalization) as well as univariate statistical analysis of single and multi-omics data sets. These methods include quality control metrics, signal drift and batch effect correction, intensity transformation, univariate hypothesis testing, but also clustering (as well as annotation of metabolomics data). The data are handled in the standard Bioconductor formats (i.e. SummarizedExperiment and MultiAssayExperiment for single and multi-omics datasets, respectively; the alternative ExpressionSet and MultiDataSet formats are also supported for convenience). As a result, all methods can be readily chained as workflows. The pipeline can be further enriched by multivariate analysis and feature selection, by using the 'ropls' and 'biosigner' packages, which support the same formats. Data can be conveniently imported from and exported to text files. Although the methods were initially targeted to metabolomics data, most of the methods can be applied to other types of omics data (e.g., transcriptomics, proteomics). biocViews: BatchEffect, Clustering, Coverage, KEGG, MassSpectrometry, Metabolomics, Normalization, Proteomics, QualityControl, Sequencing, StatisticalMethod, Transcriptomics Depends: SummarizedExperiment Imports: Biobase, biodb, biodbChebi, data.table, futile.logger, ggplot2, ggrepel, graphics, grDevices, grid, htmlwidgets, igraph, limma, methods, MultiAssayExperiment, MultiDataSet, PMCMRplus, plotly, ranger, RColorBrewer, ropls, stats, tibble, tidyr, utils, VennDiagram Suggests: BiocGenerics, BiocStyle, biosigner, CLL, knitr, omicade4, rmarkdown, testthat VignetteBuilder: knitr License: CeCILL Encoding: UTF-8 LazyLoad: yes URL: https://doi.org/10.1038/s41597-021-01095-3 RoxygenNote: 7.2.3 Config/pak/sysreqs: cmake libglpk-dev libgmp3-dev make libicu-dev libuv1-dev libxml2-dev libmpfr-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:58:57 UTC RemoteUrl: https://github.com/bioc/phenomis RemoteRef: HEAD RemoteSha: eeab6cea33f7d6b7d7258d8b61c39993a9de209f NeedsCompilation: no Packaged: 2026-04-29 08:04:08 UTC; root Author: Etienne A. Thevenot [aut, cre] (ORCID: ), Natacha Lenuzza [ctb], Marie Tremblay-Franco [ctb], Alyssa Imbert [ctb], Pierrick Roger [ctb], Eric Venot [ctb], Sylvain Dechaumet [ctb] Maintainer: Etienne A. Thevenot