Package: pfamAnalyzeR Type: Package Title: Identification of domain isotypes in pfam data Version: 1.13.0 Authors@R: person(given="Kristoffer",family="Vitting-Seerup", role=c("cre","aut"),email="k.vitting.seerup@gmail.com",comment = c(ORCID = "0000-0002-6450-0608")) Description: Protein domains is one of the most import annoation of proteins we have with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. We have recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease-specific manner. Accordingly, we find that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data. License: MIT + file LICENSE Depends: R (>= 4.3.0), readr, stringr, dplyr Imports: utils, tibble, magrittr Encoding: UTF-8 RoxygenNote: 7.2.1 Suggests: BiocStyle, knitr, rmarkdown VignetteBuilder: knitr biocViews: AlternativeSplicing, TranscriptomeVariant, BiomedicalInformatics, FunctionalGenomics, SystemsBiology, Annotation, FunctionalPrediction, GenePrediction, DataImport BugReports: https://github.com/kvittingseerup/pfamAnalyzeR/issues Config/pak/sysreqs: libicu-dev libx11-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:00:52 UTC RemoteUrl: https://github.com/bioc/pfamAnalyzeR RemoteRef: HEAD RemoteSha: bdce5208aa057de4dc4a2c35d0c5bfcc5236516b NeedsCompilation: no Packaged: 2026-05-30 07:12:56 UTC; root Author: Kristoffer Vitting-Seerup [cre, aut] (ORCID: ) Maintainer: Kristoffer Vitting-Seerup