{"pathwayId":"R-HSA-164843","pathwayName":"2-LTR circle formation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-73843","pathwayName":"5-Phosphoribose 1-diphosphate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1971475","pathwayName":"A tetrasaccharide linker sequence is required for GAG synthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1369062","pathwayName":"ABC transporters in lipid homeostasis","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-382556","pathwayName":"ABC-family proteins mediated transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9033807","pathwayName":"ABO blood group biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9660821","pathwayName":"ADORA2B mediated anti-inflammatory cytokines production","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-418592","pathwayName":"ADP signalling through P2Y purinoceptor 1","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-392170","pathwayName":"ADP signalling through P2Y purinoceptor 12","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-9700645","pathwayName":"ALK mutants bind TKIs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-112122","pathwayName":"ALKBH2 mediated reversal of alkylation damage","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-112126","pathwayName":"ALKBH3 mediated reversal of alkylation damage","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-163680","pathwayName":"AMPK inhibits chREBP transcriptional activation activity","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5467337","pathwayName":"APC truncation mutants have impaired AXIN binding","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-179409","pathwayName":"APC-Cdc20 mediated degradation of Nek2A","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174048","pathwayName":"APC/C:Cdc20 mediated degradation of Cyclin B","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174154","pathwayName":"APC/C:Cdc20 mediated degradation of Securin","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-176409","pathwayName":"APC/C:Cdc20 mediated degradation of mitotic proteins","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174178","pathwayName":"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5649702","pathwayName":"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-180689","pathwayName":"APOBEC3G mediated resistance to HIV-1 infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5624958","pathwayName":"ARL13B-mediated ciliary trafficking of INPP5E","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-170984","pathwayName":"ARMS-mediated activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9717264","pathwayName":"ASP-3026-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-380994","pathwayName":"ATF4 activates genes in response to endoplasmic reticulum  stress","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-381183","pathwayName":"ATF6 (ATF6-alpha) activates chaperone genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-381033","pathwayName":"ATF6 (ATF6-alpha) activates chaperones","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-8874177","pathwayName":"ATF6B (ATF6-beta) activates chaperones","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-1296025","pathwayName":"ATP sensitive Potassium channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-450408","pathwayName":"AUF1 (hnRNP D0) binds and destabilizes mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8854518","pathwayName":"AURKA Activation by TPX2","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5467340","pathwayName":"AXIN missense mutants destabilize the destruction complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2161541","pathwayName":"Abacavir metabolism","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-2161517","pathwayName":"Abacavir transmembrane transport","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-73930","pathwayName":"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9687136","pathwayName":"Aberrant regulation of mitotic exit in cancer due to RB1 defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2978092","pathwayName":"Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167242","pathwayName":"Abortive elongation of HIV-1 transcript in the absence of Tat","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-264642","pathwayName":"Acetylcholine Neurotransmitter Release Cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9667769","pathwayName":"Acetylcholine inhibits contraction of outer hair cells","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-399997","pathwayName":"Acetylcholine regulates insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1300645","pathwayName":"Acrosome Reaction and Sperm:Oocyte Membrane Binding","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-2122948","pathwayName":"Activated NOTCH1 Transmits Signal to the Nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9032845","pathwayName":"Activated NTRK2 signals through CDK5","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9028731","pathwayName":"Activated NTRK2 signals through FRS2 and FRS3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9032500","pathwayName":"Activated NTRK2 signals through FYN","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9028335","pathwayName":"Activated NTRK2 signals through PI3K","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9026527","pathwayName":"Activated NTRK2 signals through PLCG1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9026519","pathwayName":"Activated NTRK2 signals through RAS","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9603381","pathwayName":"Activated NTRK3 signals through PI3K","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9034793","pathwayName":"Activated NTRK3 signals through PLCG1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9034864","pathwayName":"Activated NTRK3 signals through RAS","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5625886","pathwayName":"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2033519","pathwayName":"Activated point mutants of FGFR2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-111452","pathwayName":"Activation and oligomerization of BAK protein","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-165158","pathwayName":"Activation of AKT2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-399710","pathwayName":"Activation of AMPA receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9619483","pathwayName":"Activation of AMPK downstream of NMDARs","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-176187","pathwayName":"Activation of ATR in response to replication stress","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-111447","pathwayName":"Activation of BAD and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-111446","pathwayName":"Activation of BIM and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-139910","pathwayName":"Activation of BMF and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-174577","pathwayName":"Activation of C3 and C5","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-451308","pathwayName":"Activation of Ca-permeable Kainate Receptor","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1296041","pathwayName":"Activation of G protein gated Potassium channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-936964","pathwayName":"Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1592389","pathwayName":"Activation of Matrix Metalloproteinases","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-1169091","pathwayName":"Activation of NF-kappaB in B cells","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2980767","pathwayName":"Activation of NIMA Kinases NEK9, NEK6, NEK7","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-111448","pathwayName":"Activation of NOXA and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-451307","pathwayName":"Activation of Na-permeable kainate receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-2151209","pathwayName":"Activation of PPARGC1A (PGC-1alpha) by phosphorylation","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-139915","pathwayName":"Activation of PUMA and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-428540","pathwayName":"Activation of RAC1","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9619229","pathwayName":"Activation of RAC1 downstream of NMDARs","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1169092","pathwayName":"Activation of RAS in B cells","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5635838","pathwayName":"Activation of SMO","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5617472","pathwayName":"Activation of anterior HOX genes in hindbrain development during early embryogenesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-111459","pathwayName":"Activation of caspases through apoptosome-mediated cleavage","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-2426168","pathwayName":"Activation of gene expression by SREBF (SREBP)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-450341","pathwayName":"Activation of the AP-1 family of transcription factors","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8866907","pathwayName":"Activation of the TFAP2 (AP-2) family of transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-72662","pathwayName":"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2485179","pathwayName":"Activation of the phototransduction cascade","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-75108","pathwayName":"Activation, myristolyation of BID and translocation to mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-114294","pathwayName":"Activation, translocation and oligomerization of BAX","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-1482798","pathwayName":"Acyl chain remodeling of CL","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482883","pathwayName":"Acyl chain remodeling of DAG and TAG","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482788","pathwayName":"Acyl chain remodelling of PC","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482839","pathwayName":"Acyl chain remodelling of PE","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482925","pathwayName":"Acyl chain remodelling of PG","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482922","pathwayName":"Acyl chain remodelling of PI","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1482801","pathwayName":"Acyl chain remodelling of PS","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-417973","pathwayName":"Adenosine P1 receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-170660","pathwayName":"Adenylate cyclase activating pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418990","pathwayName":"Adherens junctions interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-392023","pathwayName":"Adrenaline signalling through Alpha-2 adrenergic receptor","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-400042","pathwayName":"Adrenaline,noradrenaline inhibits insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-390696","pathwayName":"Adrenoceptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-879415","pathwayName":"Advanced glycosylation endproduct receptor signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5423646","pathwayName":"Aflatoxin activation and detoxification","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9646399","pathwayName":"Aggrephagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-8964540","pathwayName":"Alanine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1462054","pathwayName":"Alpha-defensins","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-389599","pathwayName":"Alpha-oxidation of phytanate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9645460","pathwayName":"Alpha-protein kinase 1 signaling pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-173736","pathwayName":"Alternative complement activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-375280","pathwayName":"Amine ligand-binding receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-352230","pathwayName":"Amino acid transport across the plasma membrane","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9639288","pathwayName":"Amino acids regulate mTORC1","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-141444","pathwayName":"Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-977225","pathwayName":"Amyloid fiber formation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2214320","pathwayName":"Anchoring fibril formation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-5620912","pathwayName":"Anchoring of the basal body to the plasma membrane","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-193048","pathwayName":"Androgen biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2473224","pathwayName":"Antagonism of Activin by Follistatin","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-983170","pathwayName":"Antigen Presentation: Folding, assembly and peptide loading of class I MHC","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-983695","pathwayName":"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-983168","pathwayName":"Antigen processing: Ubiquitination & Proteasome degradation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9639775","pathwayName":"Antimicrobial action and antimicrobial resistance in Mtb","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6803157","pathwayName":"Antimicrobial peptides","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-140342","pathwayName":"Apoptosis induced DNA fragmentation","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-351906","pathwayName":"Apoptotic cleavage of cell adhesion  proteins","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-111465","pathwayName":"Apoptotic cleavage of cellular proteins","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-75153","pathwayName":"Apoptotic execution phase","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-111471","pathwayName":"Apoptotic factor-mediated response","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-2142753","pathwayName":"Arachidonic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8937144","pathwayName":"Aryl hydrocarbon receptor signalling","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446203","pathwayName":"Asparagine N-linked glycosylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8963693","pathwayName":"Aspartate and asparagine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9749641","pathwayName":"Aspirin ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-175474","pathwayName":"Assembly Of The HIV Virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9609736","pathwayName":"Assembly and cell surface presentation of NMDA receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9820962","pathwayName":"Assembly and release of respiratory syncytial virus (RSV) virions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168316","pathwayName":"Assembly of Viral Components at the Budding Site","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8963889","pathwayName":"Assembly of active LPL and LIPC lipase complexes","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-2022090","pathwayName":"Assembly of collagen fibrils and other multimeric structures","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-68616","pathwayName":"Assembly of the ORC complex at the origin of replication","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-9683439","pathwayName":"Assembly of the SARS-CoV-1 Replication-Transcription Complex (RTC)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694271","pathwayName":"Assembly of the SARS-CoV-2 Replication-Transcription Complex (RTC)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-68867","pathwayName":"Assembly of the pre-replicative complex","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-390471","pathwayName":"Association of TriC/CCT with target proteins during biosynthesis","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-210455","pathwayName":"Astrocytic Glutamate-Glutamine Uptake And Metabolism","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-4608870","pathwayName":"Asymmetric localization of PCP proteins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9754706","pathwayName":"Atorvastatin ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-9678110","pathwayName":"Attachment and Entry","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694614","pathwayName":"Attachment and Entry","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-162791","pathwayName":"Attachment of GPI anchor to uPAR","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3371568","pathwayName":"Attenuation phase","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-174084","pathwayName":"Autodegradation of Cdh1 by Cdh1:APC/C","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-349425","pathwayName":"Autodegradation of the E3 ubiquitin ligase COP1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-177539","pathwayName":"Autointegration results in viral DNA circles","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-193634","pathwayName":"Axonal growth inhibition (RHOA activation)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-209563","pathwayName":"Axonal growth stimulation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9748787","pathwayName":"Azathioprine ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-5250924","pathwayName":"B-WICH complex positively regulates rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5620922","pathwayName":"BBSome-mediated cargo-targeting to cilium","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-9024909","pathwayName":"BDNF activates NTRK2 (TRKB) signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111453","pathwayName":"BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-1368108","pathwayName":"BMAL1:CLOCK,NPAS2 activates circadian gene expression","topLevelPathway":"Circadian Clock","groupedPathway":"Tissue Function","topLevelOriginal":"Circadian Clock"}
{"pathwayId":"R-HSA-210991","pathwayName":"Basigin interactions","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-1461957","pathwayName":"Beta defensins","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-77352","pathwayName":"Beta oxidation of butanoyl-CoA to acetyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77346","pathwayName":"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77350","pathwayName":"Beta oxidation of hexanoyl-CoA to butanoyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77310","pathwayName":"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77285","pathwayName":"Beta oxidation of myristoyl-CoA to lauroyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77348","pathwayName":"Beta oxidation of octanoyl-CoA to hexanoyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77305","pathwayName":"Beta oxidation of palmitoyl-CoA to myristoyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196299","pathwayName":"Beta-catenin phosphorylation cascade","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-389887","pathwayName":"Beta-oxidation of pristanoyl-CoA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-390247","pathwayName":"Beta-oxidation of very long chain fatty acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-173107","pathwayName":"Binding and entry of HIV virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4411364","pathwayName":"Binding of TCF/LEF:CTNNB1 to target gene promoters","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-141333","pathwayName":"Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018676","pathwayName":"Biosynthesis of D-series resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018677","pathwayName":"Biosynthesis of DHA-derived SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9025094","pathwayName":"Biosynthesis of DPAn-3 SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026290","pathwayName":"Biosynthesis of DPAn-3-derived maresins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9025106","pathwayName":"Biosynthesis of DPAn-6 SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9023661","pathwayName":"Biosynthesis of E-series 18(R)-resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018896","pathwayName":"Biosynthesis of E-series 18(S)-resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018679","pathwayName":"Biosynthesis of EPA-derived SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9020265","pathwayName":"Biosynthesis of aspirin-triggered D-series resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9027604","pathwayName":"Biosynthesis of electrophilic omega-3 PUFA oxo-derivatives","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026762","pathwayName":"Biosynthesis of maresin conjugates in tissue regeneration (MCTR)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018682","pathwayName":"Biosynthesis of maresins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026766","pathwayName":"Biosynthesis of protectin and resolvin conjugates in tissue regeneration (PCTR and RCTR)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018681","pathwayName":"Biosynthesis of protectins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446193","pathwayName":"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-196780","pathwayName":"Biotin transport and metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9636467","pathwayName":"Blockage of phagosome acidification","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-70895","pathwayName":"Branched-chain amino acid catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-352238","pathwayName":"Breakdown of the nuclear lamina","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-168302","pathwayName":"Budding","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-162588","pathwayName":"Budding and maturation of HIV virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-450385","pathwayName":"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8851680","pathwayName":"Butyrophilin (BTN) family interactions","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-75102","pathwayName":"C6 deamination of adenosine","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-5218900","pathwayName":"CASP8 activity is inhibited","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-9662834","pathwayName":"CD163 mediating an anti-inflammatory response","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5621575","pathwayName":"CD209 (DC-SIGN) signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5690714","pathwayName":"CD22 mediated BCR regulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-389356","pathwayName":"CD28 co-stimulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-389357","pathwayName":"CD28 dependent PI3K/Akt signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-389359","pathwayName":"CD28 dependent Vav1 pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9013148","pathwayName":"CDC42 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-68689","pathwayName":"CDC6 association with the ORC:origin complex","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-9833576","pathwayName":"CDH11 homotypic and heterotypic interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-447041","pathwayName":"CHL1 interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5607763","pathwayName":"CLEC7A (Dectin-1) induces NFAT activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5607764","pathwayName":"CLEC7A (Dectin-1) signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5660668","pathwayName":"CLEC7A/inflammasome pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6811434","pathwayName":"COPI-dependent Golgi-to-ER retrograde traffic","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-6811436","pathwayName":"COPI-independent Golgi-to-ER retrograde traffic","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-140180","pathwayName":"COX reactions","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-442720","pathwayName":"CREB1 phosphorylation through the activation of Adenylate Cyclase","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-442729","pathwayName":"CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-8874211","pathwayName":"CREB3 factors activate genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-399956","pathwayName":"CRMPs in Sema3A signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2024101","pathwayName":"CS/DS degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-389513","pathwayName":"CTLA4 inhibitory signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5358747","pathwayName":"CTNNB1 S33 mutants aren't phosphorylated","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5358749","pathwayName":"CTNNB1 S37 mutants aren't phosphorylated","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5358751","pathwayName":"CTNNB1 S45 mutants aren't phosphorylated","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5358752","pathwayName":"CTNNB1 T41 mutants aren't phosphorylated","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1296052","pathwayName":"Ca2+ activated K+ channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-4086398","pathwayName":"Ca2+ pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111997","pathwayName":"CaM pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111932","pathwayName":"CaMK IV-mediated phosphorylation of CREB","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2025928","pathwayName":"Calcineurin activates NFAT","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-419812","pathwayName":"Calcitonin-like ligand receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111933","pathwayName":"Calmodulin induced events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-901042","pathwayName":"Calnexin/calreticulin cycle","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-111957","pathwayName":"Cam-PDE 1 activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8955332","pathwayName":"Carboxyterminal post-translational modifications of tubulin","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9733709","pathwayName":"Cardiogenesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8856825","pathwayName":"Cargo recognition for clathrin-mediated endocytosis","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-200425","pathwayName":"Carnitine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-71262","pathwayName":"Carnitine synthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-140534","pathwayName":"Caspase activation via Death Receptors in the presence of ligand","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-418889","pathwayName":"Caspase activation via Dependence Receptors in the absence of ligand","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-264870","pathwayName":"Caspase-mediated cleavage of cytoskeletal proteins","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-209905","pathwayName":"Catecholamine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-426117","pathwayName":"Cation-coupled Chloride cotransporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-174184","pathwayName":"Cdc20:Phospho-APC/C mediated degradation of Cyclin A","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1222541","pathwayName":"Cell redox homeostasis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-202733","pathwayName":"Cell surface interactions at the vascular wall","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-446353","pathwayName":"Cell-extracellular matrix interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-189200","pathwayName":"Cellular hexose transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-1234174","pathwayName":"Cellular response to hypoxia","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9840373","pathwayName":"Cellular response to mitochondrial stress","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-193681","pathwayName":"Ceramide signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-163765","pathwayName":"ChREBP activates metabolic gene expression","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9613829","pathwayName":"Chaperone Mediated Autophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-380108","pathwayName":"Chemokine receptors bind chemokines","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-75035","pathwayName":"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-191273","pathwayName":"Cholesterol biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6798163","pathwayName":"Choline catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9821002","pathwayName":"Chromatin modifications during the maternal to zygotic transition (MZT)","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3247509","pathwayName":"Chromatin modifying enzymes","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-8963888","pathwayName":"Chylomicron assembly","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964026","pathwayName":"Chylomicron clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8963901","pathwayName":"Chylomicron remodeling","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5617833","pathwayName":"Cilium Assembly","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-9793528","pathwayName":"Ciprofloxacin ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-71403","pathwayName":"Citric acid cycle (TCA cycle)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-373076","pathwayName":"Class A/1 (Rhodopsin-like receptors)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-373080","pathwayName":"Class B/2 (Secretin family receptors)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-420499","pathwayName":"Class C/3 (Metabotropic glutamate/pheromone receptors)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9603798","pathwayName":"Class I peroxisomal membrane protein import","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-1296053","pathwayName":"Classical Kir channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-173623","pathwayName":"Classical antibody-mediated complement activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8856828","pathwayName":"Clathrin-mediated endocytosis","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-110331","pathwayName":"Cleavage of the damaged purine","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-110329","pathwayName":"Cleavage of the damaged pyrimidine","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9759218","pathwayName":"Cobalamin (Cbl) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196783","pathwayName":"Coenzyme A biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2470946","pathwayName":"Cohesin Loading onto Chromatin","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1650814","pathwayName":"Collagen biosynthesis and modifying enzymes","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-8948216","pathwayName":"Collagen chain trimerization","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-1442490","pathwayName":"Collagen degradation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-140875","pathwayName":"Common Pathway of Fibrin Clot Formation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-8948700","pathwayName":"Competing endogenous RNAs (ceRNAs) regulate PTEN translation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6799198","pathwayName":"Complex I biogenesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2514853","pathwayName":"Condensation of Prometaphase Chromosomes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2299718","pathwayName":"Condensation of Prophase Chromosomes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5674400","pathwayName":"Constitutive Signaling by AKT1 E17K in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2219530","pathwayName":"Constitutive Signaling by Aberrant PI3K in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5637810","pathwayName":"Constitutive Signaling by EGFRvIII","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1236382","pathwayName":"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2691232","pathwayName":"Constitutive Signaling by NOTCH1 HD Domain Mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2894862","pathwayName":"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2644606","pathwayName":"Constitutive Signaling by NOTCH1 PEST Domain Mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2660826","pathwayName":"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9634285","pathwayName":"Constitutive Signaling by Overexpressed ERBB2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-176407","pathwayName":"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-6814122","pathwayName":"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-388841","pathwayName":"Costimulation by the CD28 family","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-71288","pathwayName":"Creatine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8949613","pathwayName":"Cristae formation","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-1236973","pathwayName":"Cross-presentation of particulate exogenous antigens (phagosomes)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1236978","pathwayName":"Cross-presentation of soluble exogenous antigens (endosomes)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2243919","pathwayName":"Crosslinking of collagen fibrils","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-69273","pathwayName":"Cyclin A/B1/B2 associated events during G2/M transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69656","pathwayName":"Cyclin A:Cdk2-associated events at S phase entry","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69231","pathwayName":"Cyclin D associated events in G1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69202","pathwayName":"Cyclin E associated events during G1/S transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1614603","pathwayName":"Cysteine formation from homocysteine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-211897","pathwayName":"Cytochrome P450 - arranged by substrate type","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9707564","pathwayName":"Cytoprotection by HMOX1","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-2564830","pathwayName":"Cytosolic iron-sulfur cluster assembly","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1834949","pathwayName":"Cytosolic sensors of pathogen-associated DNA","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-156584","pathwayName":"Cytosolic sulfonation of small molecules","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-379716","pathwayName":"Cytosolic tRNA aminoacylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1489509","pathwayName":"DAG and IP3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2172127","pathwayName":"DAP12 interactions","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2424491","pathwayName":"DAP12 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-180024","pathwayName":"DARPP-32 events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418885","pathwayName":"DCC mediated attractive signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-168928","pathwayName":"DDX58/IFIH1-mediated induction of interferon-alpha/beta","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3134963","pathwayName":"DEx/H-box helicases activate type I IFN and inflammatory cytokines production","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5696394","pathwayName":"DNA Damage Recognition in GG-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-2559586","pathwayName":"DNA Damage/Telomere Stress Induced Senescence","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-5334118","pathwayName":"DNA methylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-376172","pathwayName":"DSCAM interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3769402","pathwayName":"Deactivation of the beta-catenin transactivating complex","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-429947","pathwayName":"Deadenylation of mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-5607761","pathwayName":"Dectin-1 mediated noncanonical NF-kB signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5621480","pathwayName":"Dectin-2 family","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5682113","pathwayName":"Defective ABCA1 causes TGD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5683177","pathwayName":"Defective ABCC8 can cause hypo- and hyper-glycemias","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5678420","pathwayName":"Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5683329","pathwayName":"Defective ABCD4 causes MAHCJ","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5679096","pathwayName":"Defective ABCG5 causes sitosterolemia","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5679090","pathwayName":"Defective ABCG8 causes GBD4 and sitosterolemia","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579007","pathwayName":"Defective ACY1 causes encephalopathy","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5578997","pathwayName":"Defective AHCY causes HMAHCHD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5633231","pathwayName":"Defective ALG14 causes ALG14-CMS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359462","pathwayName":"Defective AMN causes MGA1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9734195","pathwayName":"Defective APRT disrupts adenine salvage","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3560801","pathwayName":"Defective B3GAT3 causes JDSSDHD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9616334","pathwayName":"Defective Base Excision Repair Associated with NEIL1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9629232","pathwayName":"Defective Base Excision Repair Associated with NEIL3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083632","pathwayName":"Defective C1GALT1C1 causes TNPS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359485","pathwayName":"Defective CD320 causes MMATC","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5678895","pathwayName":"Defective CFTR causes cystic fibrosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619060","pathwayName":"Defective CP causes aceruloplasminemia (ACERULOP)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5688890","pathwayName":"Defective CSF2RA causes SMDP4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5688849","pathwayName":"Defective CSF2RB causes SMDP5","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359463","pathwayName":"Defective CUBN causes MGA1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579026","pathwayName":"Defective CYP11A1 causes AICSR","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4755609","pathwayName":"Defective DHDDS causes RP59","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4717374","pathwayName":"Defective DPM1 causes DPM1-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4719377","pathwayName":"Defective DPM2 causes DPM2-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4719360","pathwayName":"Defective DPM3 causes DPM3-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656253","pathwayName":"Defective EXT1 causes exostoses 1, TRPS2 and CHDS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656237","pathwayName":"Defective EXT2 causes exostoses 2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672387","pathwayName":"Defective F8 accelerates dissociation of the A2 domain","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672395","pathwayName":"Defective F8 binding to the cell membrane","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672393","pathwayName":"Defective F8 binding to von Willebrand factor","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672391","pathwayName":"Defective F8 cleavage by thrombin","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673221","pathwayName":"Defective F9 activation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673202","pathwayName":"Defective F9 variant does not activate FX","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579019","pathwayName":"Defective FMO3 causes TMAU","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5609977","pathwayName":"Defective GALE causes EDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5578999","pathwayName":"Defective GCLC causes HAGGSD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579006","pathwayName":"Defective GSS causes GSS deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9704331","pathwayName":"Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9704646","pathwayName":"Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3371599","pathwayName":"Defective HLCS causes multiple carboxylase deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9734281","pathwayName":"Defective HPRT1 disrupts guanine and hypoxanthine salvage","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9645722","pathwayName":"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083627","pathwayName":"Defective LARGE causes MDDGA6 and MDDGB6","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4793950","pathwayName":"Defective MAN1B1 causes MRT15","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579012","pathwayName":"Defective MAOA causes BRUNS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579024","pathwayName":"Defective MAT1A causes MATD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359475","pathwayName":"Defective MMAA causes MMA, cblA type","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359473","pathwayName":"Defective MMADHC causes MMAHCD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4793954","pathwayName":"Defective MOGS causes CDG-2b","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359469","pathwayName":"Defective MTR causes HMAG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359467","pathwayName":"Defective MTRR causes HMAE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359478","pathwayName":"Defective MUT causes MMAM","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9608290","pathwayName":"Defective MUTYH substrate processing","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4341670","pathwayName":"Defective NEU1 causes sialidosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9630221","pathwayName":"Defective NTHL1 substrate processing","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9656256","pathwayName":"Defective OGG1 Substrate Processing","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5609974","pathwayName":"Defective PGM1 causes PGM1-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9735763","pathwayName":"Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083633","pathwayName":"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083629","pathwayName":"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9693928","pathwayName":"Defective RIPK1-mediated regulated necrosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9657689","pathwayName":"Defective SERPING1 causes hereditary angioedema","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619070","pathwayName":"Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619113","pathwayName":"Defective SLC3A1 causes cystinuria (CSNU)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5655799","pathwayName":"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619049","pathwayName":"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660862","pathwayName":"Defective SLC7A7 causes lysinuric protein intolerance (LPI)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660883","pathwayName":"Defective SLC7A9 causes cystinuria (CSNU)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619107","pathwayName":"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9845622","pathwayName":"Defective VWF binding to collagen type I","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9845621","pathwayName":"Defective VWF cleavage by ADAMTS13 variant","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9661069","pathwayName":"Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9846298","pathwayName":"Defective binding of VWF variant to GPIb:IX:V","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672396","pathwayName":"Defective cofactor function of FVIIIa variant","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672383","pathwayName":"Defective factor IX causes thrombophilia","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9657688","pathwayName":"Defective factor XII causes hereditary angioedema","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9701192","pathwayName":"Defective homologous recombination repair (HRR) due to BRCA1 loss of function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9710421","pathwayName":"Defective pyroptosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9824856","pathwayName":"Defective regulation of TLR7 by endogenous ligand","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1461973","pathwayName":"Defensins","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-4641257","pathwayName":"Degradation of AXIN","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-4641258","pathwayName":"Degradation of DVL","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-916853","pathwayName":"Degradation of GABA","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-5610780","pathwayName":"Degradation of GLI1 by the proteasome","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5610783","pathwayName":"Degradation of GLI2 by the proteasome","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-195253","pathwayName":"Degradation of beta-catenin by the destruction complex","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1614558","pathwayName":"Degradation of cysteine and homocysteine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1474228","pathwayName":"Degradation of the extracellular matrix","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-4419969","pathwayName":"Depolymerization of the Nuclear Lamina","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-606279","pathwayName":"Deposition of new CENPA-containing nucleosomes at the centromere","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8862803","pathwayName":"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3299685","pathwayName":"Detoxification of Reactive Oxygen Species","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-8935690","pathwayName":"Digestion","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-189085","pathwayName":"Digestion of dietary carbohydrate","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-192456","pathwayName":"Digestion of dietary lipid","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-69416","pathwayName":"Dimerization of procaspase-8","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-4641262","pathwayName":"Disassembly of the destruction complex and recruitment of AXIN to the membrane","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-114516","pathwayName":"Disinhibition of SNARE formation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-110357","pathwayName":"Displacement of DNA glycosylase by APEX1","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-75205","pathwayName":"Dissolution of Fibrin Clot","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-212676","pathwayName":"Dopamine Neurotransmitter Release Cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-379401","pathwayName":"Dopamine clearance from the synaptic cleft","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-390651","pathwayName":"Dopamine receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8863795","pathwayName":"Downregulation of ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1358803","pathwayName":"Downregulation of ERBB2:ERBB3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1253288","pathwayName":"Downregulation of ERBB4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2173788","pathwayName":"Downregulation of TGF-beta receptor signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-202424","pathwayName":"Downstream TCR signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-186763","pathwayName":"Downstream signal transduction","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654687","pathwayName":"Downstream signaling of activated FGFR1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9665737","pathwayName":"Drug resistance in ERBB2 TMD/JMD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9754119","pathwayName":"Drug-mediated inhibition of CDK4/CDK6 activity","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9652282","pathwayName":"Drug-mediated inhibition of ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9734091","pathwayName":"Drug-mediated inhibition of MET activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5696400","pathwayName":"Dual Incision in GG-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-6782135","pathwayName":"Dual incision in TC-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-113507","pathwayName":"E2F-enabled inhibition of pre-replication complex formation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8866654","pathwayName":"E3 ubiquitin ligases ubiquitinate target proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3000178","pathwayName":"ECM proteoglycans","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-2179392","pathwayName":"EGFR Transactivation by Gastrin","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-182971","pathwayName":"EGFR downregulation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-212718","pathwayName":"EGFR interacts with phospholipase C-gamma","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9619665","pathwayName":"EGR2 and SOX10-mediated initiation of Schwann cell myelination","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9648025","pathwayName":"EML4 and NUDC in mitotic spindle formation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2682334","pathwayName":"EPH-Ephrin signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3928665","pathwayName":"EPH-ephrin mediated repulsion of cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3928663","pathwayName":"EPHA-mediated growth cone collapse","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3928662","pathwayName":"EPHB-mediated forward signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-901032","pathwayName":"ER Quality Control Compartment (ERQC)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1236974","pathwayName":"ER-Phagosome pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8847993","pathwayName":"ERBB2 Activates PTK6 Signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6785631","pathwayName":"ERBB2 Regulates Cell Motility","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-427389","pathwayName":"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939211","pathwayName":"ESR-mediated signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-162594","pathwayName":"Early Phase of HIV Life Cycle","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-391903","pathwayName":"Eicosanoid ligand-binding receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1566948","pathwayName":"Elastic fibre formation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-112303","pathwayName":"Electric Transmission Across Gap Junctions","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-2395516","pathwayName":"Electron transport from NADPH to Ferredoxin","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-139853","pathwayName":"Elevation of cytosolic Ca2+ levels","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-211976","pathwayName":"Endogenous sterols","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-917729","pathwayName":"Endosomal Sorting Complex Required For Transport (ESCRT)","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-1236977","pathwayName":"Endosomal/Vacuolar pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-380972","pathwayName":"Energy dependent regulation of mTOR by LKB1-AMPK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9845620","pathwayName":"Enhanced binding of GP1BA variant to VWF multimer:collagen","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9845619","pathwayName":"Enhanced cleavage of VWF variant by ADAMTS13","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168275","pathwayName":"Entry of Influenza Virion into Host Cell via Endocytosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-379398","pathwayName":"Enzymatic degradation of Dopamine by monoamine oxidase","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-379397","pathwayName":"Enzymatic degradation of dopamine by COMT","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-3928664","pathwayName":"Ephrin signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9758919","pathwayName":"Epithelial-Mesenchymal Transition (EMT) during gastrulation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-1237044","pathwayName":"Erythrocytes take up carbon dioxide and release oxygen","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-1247673","pathwayName":"Erythrocytes take up oxygen and release carbon dioxide","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9027276","pathwayName":"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9027277","pathwayName":"Erythropoietin activates Phospholipase C gamma (PLCG)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9027284","pathwayName":"Erythropoietin activates RAS","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9027283","pathwayName":"Erythropoietin activates STAT5","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5657562","pathwayName":"Essential fructosuria","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2468052","pathwayName":"Establishment of Sister Chromatid Cohesion","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-193144","pathwayName":"Estrogen biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018519","pathwayName":"Estrogen-dependent gene expression","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9634638","pathwayName":"Estrogen-dependent nuclear events downstream of ESR-membrane signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9634635","pathwayName":"Estrogen-stimulated signaling through PRKCZ","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-71384","pathwayName":"Ethanol oxidation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156842","pathwayName":"Eukaryotic Translation Elongation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-72764","pathwayName":"Eukaryotic Translation Termination","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9833109","pathwayName":"Evasion by RSV of host interferon responses","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8941413","pathwayName":"Events associated with phagocytolytic activity of PMN cells","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9752946","pathwayName":"Expression and translocation of olfactory receptors","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9009391","pathwayName":"Extra-nuclear estrogen signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-140834","pathwayName":"Extrinsic Pathway of Fibrin Clot Formation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-9837092","pathwayName":"FASTK family proteins regulate processing and stability of mitochondrial RNAs","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8854050","pathwayName":"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2871809","pathwayName":"FCERI mediated Ca+2 mobilization","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2871796","pathwayName":"FCERI mediated MAPK activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2871837","pathwayName":"FCERI mediated NF-kB activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2029481","pathwayName":"FCGR activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9664323","pathwayName":"FCGR3A-mediated IL10 synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9664422","pathwayName":"FCGR3A-mediated phagocytosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190370","pathwayName":"FGFR1b ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190374","pathwayName":"FGFR1c and Klotho ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190373","pathwayName":"FGFR1c ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6803529","pathwayName":"FGFR2 alternative splicing","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190377","pathwayName":"FGFR2b ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190375","pathwayName":"FGFR2c ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190371","pathwayName":"FGFR3b ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190372","pathwayName":"FGFR3c ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-190322","pathwayName":"FGFR4 ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1839128","pathwayName":"FGFR4 mutant receptor activation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5658623","pathwayName":"FGFRL1 modulation of FGFR1 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9607240","pathwayName":"FLT3 Signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9702509","pathwayName":"FLT3 mutants bind TKIs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9706377","pathwayName":"FLT3 signaling by CBL mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9706374","pathwayName":"FLT3 signaling through SRC family kinases","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-217271","pathwayName":"FMO oxidises nucleophiles","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9617828","pathwayName":"FOXO-mediated transcription of cell cycle genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9614657","pathwayName":"FOXO-mediated transcription of cell death genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9615017","pathwayName":"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5654693","pathwayName":"FRS-mediated FGFR1 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654700","pathwayName":"FRS-mediated FGFR2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654706","pathwayName":"FRS-mediated FGFR3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654712","pathwayName":"FRS-mediated FGFR4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-983231","pathwayName":"Factors involved in megakaryocyte development and platelet production","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-6783310","pathwayName":"Fanconi Anemia Pathway","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-75157","pathwayName":"FasL/ CD95L signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-434316","pathwayName":"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-75105","pathwayName":"Fatty acyl-CoA biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2454202","pathwayName":"Fc epsilon receptor (FCERI) signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1566977","pathwayName":"Fibronectin matrix formation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-2855086","pathwayName":"Ficolins bind to repetitive carbohydrate structures on the target cell surface","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-390450","pathwayName":"Folding of actin by CCT/TriC","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-163210","pathwayName":"Formation of ATP by chemiosmotic coupling","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-167152","pathwayName":"Formation of HIV elongation complex in the absence of HIV Tat","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167200","pathwayName":"Formation of HIV-1 elongation complex containing HIV-1 Tat","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5696395","pathwayName":"Formation of Incision Complex in GG-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-112382","pathwayName":"Formation of RNA Pol II elongation complex","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-2559584","pathwayName":"Formation of Senescence-Associated Heterochromatin Foci (SAHF)","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-6781823","pathwayName":"Formation of TC-NER Pre-Incision Complex","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9772755","pathwayName":"Formation of WDR5-containing histone-modifying complexes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-72689","pathwayName":"Formation of a pool of free 40S subunits","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-196025","pathwayName":"Formation of annular gap junctions","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-111458","pathwayName":"Formation of apoptosome","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-9796292","pathwayName":"Formation of axial mesoderm","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9823730","pathwayName":"Formation of definitive endoderm","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-77042","pathwayName":"Formation of editosomes by ADAR proteins","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9761174","pathwayName":"Formation of intermediate mesoderm","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9758920","pathwayName":"Formation of lateral plate mesoderm","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9793380","pathwayName":"Formation of paraxial mesoderm","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-113418","pathwayName":"Formation of the Early Elongation Complex","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-75094","pathwayName":"Formation of the Editosome","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-167158","pathwayName":"Formation of the HIV-1 Early Elongation Complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-173599","pathwayName":"Formation of the active cofactor, UDP-glucuronate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9823739","pathwayName":"Formation of the anterior neural plate","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-201722","pathwayName":"Formation of the beta-catenin:TCF transactivating complex","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6809371","pathwayName":"Formation of the cornified envelope","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9830364","pathwayName":"Formation of the nephric duct","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9832991","pathwayName":"Formation of the posterior neural plate","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-72695","pathwayName":"Formation of the ternary complex, and subsequently, the 43S complex","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9830674","pathwayName":"Formation of the ureteric bud","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-389960","pathwayName":"Formation of tubulin folding intermediates by CCT/TriC","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5661270","pathwayName":"Formation of xylulose-5-phosphate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-444473","pathwayName":"Formyl peptide receptors bind formyl peptides and many other ligands","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-444209","pathwayName":"Free fatty acid receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-170968","pathwayName":"Frs2-mediated activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5652227","pathwayName":"Fructose biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-70350","pathwayName":"Fructose catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-168288","pathwayName":"Fusion of the Influenza Virion to the Host Cell Endosome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-416482","pathwayName":"G alpha (12/13) signalling events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418594","pathwayName":"G alpha (i) signalling events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-416476","pathwayName":"G alpha (q) signalling events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418555","pathwayName":"G alpha (s) signalling events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418597","pathwayName":"G alpha (z) signalling events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8964315","pathwayName":"G beta:gamma signalling through BTK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8964616","pathwayName":"G beta:gamma signalling through CDC42","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-392451","pathwayName":"G beta:gamma signalling through PI3Kgamma","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-418217","pathwayName":"G beta:gamma signalling through PLC beta","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-202040","pathwayName":"G-protein activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1538133","pathwayName":"G0 and Early G1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69205","pathwayName":"G1/S-Specific Transcription","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-68911","pathwayName":"G2 Phase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69481","pathwayName":"G2/M Checkpoints","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69473","pathwayName":"G2/M DNA damage checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69478","pathwayName":"G2/M DNA replication checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-180292","pathwayName":"GAB1 signalosome","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-977444","pathwayName":"GABA B receptor activation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-977443","pathwayName":"GABA receptor activation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-888568","pathwayName":"GABA synthesis","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-888590","pathwayName":"GABA synthesis, release, reuptake and degradation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-6787639","pathwayName":"GDP-fucose biosynthesis","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5635851","pathwayName":"GLI proteins bind promoters of Hh responsive genes to promote transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5610785","pathwayName":"GLI3 is processed to GLI3R by the proteasome","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-430116","pathwayName":"GP1b-IX-V activation signalling","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-9634597","pathwayName":"GPER1 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-114604","pathwayName":"GPVI-mediated activation cascade","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-179812","pathwayName":"GRB2 events in EGFR signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1963640","pathwayName":"GRB2 events in ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1306955","pathwayName":"GRB7 events in ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9762114","pathwayName":"GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-72706","pathwayName":"GTP hydrolysis and joining of the 60S ribosomal subunit","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9726842","pathwayName":"Gain-of-function MRAS complexes activate RAF signaling","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-70370","pathwayName":"Galactose catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-163841","pathwayName":"Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-159740","pathwayName":"Gamma-carboxylation of protein precursors","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-190861","pathwayName":"Gap junction assembly","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-190873","pathwayName":"Gap junction degradation","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-5696397","pathwayName":"Gap-filling DNA repair synthesis and ligation in GG-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-6782210","pathwayName":"Gap-filling DNA repair synthesis and ligation in TC-NER","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-881907","pathwayName":"Gastrin-CREB signalling pathway via PKC and MAPK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8950505","pathwayName":"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-202433","pathwayName":"Generation of second messenger molecules","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-212436","pathwayName":"Generic Transcription Pathway","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9754189","pathwayName":"Germ layer formation at gastrulation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-163359","pathwayName":"Glucagon signaling in metabolic regulation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-381676","pathwayName":"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-420092","pathwayName":"Glucagon-type ligand receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-194002","pathwayName":"Glucocorticoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-70263","pathwayName":"Gluconeogenesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156588","pathwayName":"Glucuronidation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-210500","pathwayName":"Glutamate Neurotransmitter Release Cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-8964539","pathwayName":"Glutamate and glutamine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156590","pathwayName":"Glutathione conjugation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-174403","pathwayName":"Glutathione synthesis and recycling","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483206","pathwayName":"Glycerophospholipid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6783984","pathwayName":"Glycine degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-70221","pathwayName":"Glycogen breakdown (glycogenolysis)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3858516","pathwayName":"Glycogen storage disease type 0 (liver GYS2)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3828062","pathwayName":"Glycogen storage disease type 0 (muscle GYS1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5357609","pathwayName":"Glycogen storage disease type II (GAA)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3878781","pathwayName":"Glycogen storage disease type IV (GBE1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3814836","pathwayName":"Glycogen storage disease type XV (GYG1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3322077","pathwayName":"Glycogen synthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-70171","pathwayName":"Glycolysis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-209822","pathwayName":"Glycoprotein hormones","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9840309","pathwayName":"Glycosphingolipid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9840310","pathwayName":"Glycosphingolipid catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9845576","pathwayName":"Glycosphingolipid transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-389661","pathwayName":"Glyoxylate metabolism and glycine degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-432722","pathwayName":"Golgi Associated Vesicle Biogenesis","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-162658","pathwayName":"Golgi Cisternae Pericentriolar Stack Reorganization","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-982772","pathwayName":"Growth hormone receptor signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3214847","pathwayName":"HATs acetylate histones","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-9609690","pathwayName":"HCMV Early Events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9610379","pathwayName":"HCMV Late Events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1296061","pathwayName":"HCN channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-3214815","pathwayName":"HDACs deacetylate histones","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-8963896","pathwayName":"HDL assembly","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964011","pathwayName":"HDL clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964058","pathwayName":"HDL remodeling","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-3214842","pathwayName":"HDMs demethylate histones","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-5685942","pathwayName":"HDR through Homologous Recombination (HRR)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5685939","pathwayName":"HDR through MMEJ (alt-NHEJ)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5685938","pathwayName":"HDR through Single Strand Annealing (SSA)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-167161","pathwayName":"HIV Transcription Initiation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167287","pathwayName":"HIV elongation arrest and recovery","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2022928","pathwayName":"HS-GAG biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2024096","pathwayName":"HS-GAG degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3371511","pathwayName":"HSF1 activation","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-3371571","pathwayName":"HSF1-dependent transactivation","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-3371497","pathwayName":"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-5610787","pathwayName":"Hedgehog 'off' state","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5632684","pathwayName":"Hedgehog 'on' state","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5358346","pathwayName":"Hedgehog ligand biogenesis","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-189451","pathwayName":"Heme biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-189483","pathwayName":"Heme degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9707616","pathwayName":"Heme signaling","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-5657560","pathwayName":"Hereditary fructose intolerance","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5362768","pathwayName":"Hh mutants are degraded by ERAD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-629597","pathwayName":"Highly calcium permeable nicotinic acetylcholine receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-629594","pathwayName":"Highly calcium permeable postsynaptic nicotinic acetylcholine receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-629587","pathwayName":"Highly sodium permeable postsynaptic acetylcholine nicotinic receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-390650","pathwayName":"Histamine receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-70921","pathwayName":"Histidine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5693579","pathwayName":"Homologous DNA Pairing and Strand Exchange","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-375281","pathwayName":"Hormone ligand-binding receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-450520","pathwayName":"HuR (ELAVL1) binds and stabilizes mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-2160916","pathwayName":"Hyaluronan uptake and degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483115","pathwayName":"Hydrolysis of LPC","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3296197","pathwayName":"Hydroxycarboxylic acid-binding receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-204626","pathwayName":"Hypusine synthesis from eIF5A-lysine","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9732724","pathwayName":"IFNG signaling activates MAPKs","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-937041","pathwayName":"IKK complex recruitment mediated by RIP1","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6788467","pathwayName":"IL-6-type cytokine receptor ligand interactions","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-937039","pathwayName":"IRAK1 recruits IKK complex","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-975144","pathwayName":"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-937042","pathwayName":"IRAK2 mediated activation of TAK1 complex","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-975163","pathwayName":"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5603041","pathwayName":"IRAK4 deficiency (TLR2/4)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5603037","pathwayName":"IRAK4 deficiency (TLR5)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-381070","pathwayName":"IRE1alpha activates chaperones","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-1606341","pathwayName":"IRF3 mediated activation of type 1 IFN","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3270619","pathwayName":"IRF3-mediated induction of type I IFN","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-74713","pathwayName":"IRS activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-112399","pathwayName":"IRS-mediated signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2428928","pathwayName":"IRS-related events triggered by IGF1R","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1169408","pathwayName":"ISG15 antiviral mechanism","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5603029","pathwayName":"IkBA variant leads to EDA-ID","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-198933","pathwayName":"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9709603","pathwayName":"Impaired BRCA2 binding to PALB2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9709570","pathwayName":"Impaired BRCA2 binding to RAD51","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9709275","pathwayName":"Impaired BRCA2 translocation to the nucleus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-141430","pathwayName":"Inactivation of APC/C via direct inhibition of the APC/C complex","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-428543","pathwayName":"Inactivation of CDC42 and RAC1","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9705462","pathwayName":"Inactivation of CSF3 (G-CSF) signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2514859","pathwayName":"Inactivation, recovery and regulation of the phototransduction cascade","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9733458","pathwayName":"Induction of Cell-Cell Fusion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168255","pathwayName":"Influenza Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168277","pathwayName":"Influenza Virus Induced Apoptosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-997272","pathwayName":"Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9670095","pathwayName":"Inhibition of DNA recombination at telomere","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-168315","pathwayName":"Inhibition of Host mRNA Processing and RNA Silencing","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168888","pathwayName":"Inhibition of IFN-beta","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-169131","pathwayName":"Inhibition of PKR","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5638303","pathwayName":"Inhibition of Signaling by Overexpressed EGFR","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-165181","pathwayName":"Inhibition of TSC complex formation by PKB","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9635644","pathwayName":"Inhibition of membrane repair","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9636249","pathwayName":"Inhibition of nitric oxide production","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-113501","pathwayName":"Inhibition of replication initiation of damaged DNA by RB1/E2F1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-141405","pathwayName":"Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-166663","pathwayName":"Initial triggering of complement","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2995383","pathwayName":"Initiation of Nuclear Envelope (NE) Reformation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8876493","pathwayName":"InlA-mediated entry of Listeria monocytogenes into host cells","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8875360","pathwayName":"InlB-mediated entry of Listeria monocytogenes into host cell","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9609523","pathwayName":"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-163754","pathwayName":"Insulin effects increased synthesis of Xylulose-5-Phosphate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-264876","pathwayName":"Insulin processing","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-77387","pathwayName":"Insulin receptor recycling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-74751","pathwayName":"Insulin receptor signalling cascade","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-428359","pathwayName":"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-163685","pathwayName":"Integration of energy metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-162592","pathwayName":"Integration of provirus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-175567","pathwayName":"Integration of viral DNA into host genomic DNA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-216083","pathwayName":"Integrin cell surface interactions","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-2534343","pathwayName":"Interaction With Cumulus Cells And The Zona Pellucida","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-445095","pathwayName":"Interaction between L1 and Ankyrins","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8854521","pathwayName":"Interaction between PHLDA1 and AURKA","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-176034","pathwayName":"Interactions of Tat with host cellular proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-499943","pathwayName":"Interconversion of nucleotide di- and triphosphates","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-351200","pathwayName":"Interconversion of polyamines","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-909733","pathwayName":"Interferon alpha/beta signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-877300","pathwayName":"Interferon gamma signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-912526","pathwayName":"Interleukin receptor SHC signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-448706","pathwayName":"Interleukin-1 processing","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020702","pathwayName":"Interleukin-1 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6783783","pathwayName":"Interleukin-10 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020591","pathwayName":"Interleukin-12 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8983432","pathwayName":"Interleukin-15 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-448424","pathwayName":"Interleukin-17 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9012546","pathwayName":"Interleukin-18 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-451927","pathwayName":"Interleukin-2 family signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020558","pathwayName":"Interleukin-2 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8854691","pathwayName":"Interleukin-20 family signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020958","pathwayName":"Interleukin-21 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020933","pathwayName":"Interleukin-23 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9020956","pathwayName":"Interleukin-27 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-512988","pathwayName":"Interleukin-3, Interleukin-5 and GM-CSF signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9014843","pathwayName":"Interleukin-33 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8984722","pathwayName":"Interleukin-35 Signalling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9014826","pathwayName":"Interleukin-36 pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9008059","pathwayName":"Interleukin-37 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9007892","pathwayName":"Interleukin-38 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6785807","pathwayName":"Interleukin-4 and Interleukin-13 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1059683","pathwayName":"Interleukin-6 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1266695","pathwayName":"Interleukin-7 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8985947","pathwayName":"Interleukin-9 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8981373","pathwayName":"Intestinal hexose absorption","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-8942233","pathwayName":"Intestinal infectious diseases","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8963678","pathwayName":"Intestinal lipid absorption","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-5659898","pathwayName":"Intestinal saccharidase deficiencies","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6811438","pathwayName":"Intra-Golgi traffic","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-8981607","pathwayName":"Intracellular oxygen transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5620924","pathwayName":"Intraflagellar transport","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-140837","pathwayName":"Intrinsic Pathway of Fibrin Clot Formation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-8941237","pathwayName":"Invadopodia formation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-983712","pathwayName":"Ion channel transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5578775","pathwayName":"Ion homeostasis","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-6803544","pathwayName":"Ion influx/efflux at host-pathogen interface","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-936837","pathwayName":"Ion transport by P-type ATPases","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-917937","pathwayName":"Iron uptake and transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-450321","pathwayName":"JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5689877","pathwayName":"Josephin domain DUBs","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9755511","pathwayName":"KEAP1-NFE2L2 pathway","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9669921","pathwayName":"KIT mutants bind TKIs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-450604","pathwayName":"KSRP (KHSRP) binds and destabilizes mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9702569","pathwayName":"KW2449-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2022854","pathwayName":"Keratan sulfate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2022857","pathwayName":"Keratan sulfate degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6805567","pathwayName":"Keratinization","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-983189","pathwayName":"Kinesins","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-156827","pathwayName":"L13a-mediated translational silencing of Ceruloplasmin expression","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-373760","pathwayName":"L1CAM interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8964038","pathwayName":"LDL clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964041","pathwayName":"LDL remodeling","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5682910","pathwayName":"LGI-ADAM interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5340573","pathwayName":"LGK974 inhibits PORCN","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3134973","pathwayName":"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9664535","pathwayName":"LTC4-CYSLTR mediated IL4 production","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5653890","pathwayName":"Lactose synthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3000157","pathwayName":"Laminin interactions","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-9615710","pathwayName":"Late endosomal microautophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-166662","pathwayName":"Lectin pathway of complement activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-391906","pathwayName":"Leukotriene receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5632681","pathwayName":"Ligand-receptor interactions","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2046105","pathwayName":"Linoleic acid (LA) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8964572","pathwayName":"Lipid particle organization","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9613354","pathwayName":"Lipophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-446343","pathwayName":"Localization of the PINCH-ILK-PARVIN complex to focal adhesions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9620244","pathwayName":"Long-term potentiation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-2644607","pathwayName":"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9022538","pathwayName":"Loss of MECP2 binding ability to 5mC-DNA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9022537","pathwayName":"Loss of MECP2 binding ability to the NCoR/SMRT complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-380259","pathwayName":"Loss of Nlp from mitotic centrosomes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9022535","pathwayName":"Loss of phosphorylation of MECP2 at T308","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-380284","pathwayName":"Loss of proteins required for interphase microtubule organization from the centrosome","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-71064","pathwayName":"Lysine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8853383","pathwayName":"Lysosomal oligosaccharide catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-432720","pathwayName":"Lysosome Vesicle Biogenesis","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-419408","pathwayName":"Lysosphingolipid and LPA receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9820841","pathwayName":"M-decay: degradation of maternal mRNAs by maternally stored factors","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5674135","pathwayName":"MAP2K and MAPK activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5684264","pathwayName":"MAP3K8 (TPL2)-dependent MAPK1/3 activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-112411","pathwayName":"MAPK1 (ERK2) activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-110056","pathwayName":"MAPK3 (ERK1) activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5687128","pathwayName":"MAPK6/MAPK4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2465910","pathwayName":"MASTL Facilitates Mitotic Progression","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9851151","pathwayName":"MDK and PTN in ALK signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9022699","pathwayName":"MECP2 regulates neuronal receptors and channels","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9022707","pathwayName":"MECP2 regulates transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9022927","pathwayName":"MECP2 regulates transcription of genes involved in GABA signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9022702","pathwayName":"MECP2 regulates transcription of neuronal ligands","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6806942","pathwayName":"MET Receptor Activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8851907","pathwayName":"MET activates PI3K/AKT signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8874081","pathwayName":"MET activates PTK2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8865999","pathwayName":"MET activates PTPN11","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8875555","pathwayName":"MET activates RAP1 and RAC1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8851805","pathwayName":"MET activates RAS signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8875791","pathwayName":"MET activates STAT3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8875513","pathwayName":"MET interacts with TNS proteins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8875656","pathwayName":"MET receptor recycling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5657655","pathwayName":"MGMT-mediated DNA damage reversal","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-2132295","pathwayName":"MHC class II antigen presentation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2206296","pathwayName":"MPS II - Hunter syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206285","pathwayName":"MPS VI - Maroteaux-Lamy syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660489","pathwayName":"MTF1 activates gene expression","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-165159","pathwayName":"MTOR signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1632852","pathwayName":"Macroautophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-6791226","pathwayName":"Major pathway of rRNA processing in the nucleolus and cytosol","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9856872","pathwayName":"Malate-aspartate shuttle","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9636667","pathwayName":"Manipulation of host energy metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9854311","pathwayName":"Maturation of TCA enzymes and regulation of TCA cycle","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9828806","pathwayName":"Maturation of hRSV A proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9683610","pathwayName":"Maturation of nucleoprotein","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694631","pathwayName":"Maturation of nucleoprotein","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9683673","pathwayName":"Maturation of protein 3a","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694719","pathwayName":"Maturation of protein 3a","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9683683","pathwayName":"Maturation of protein E","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694493","pathwayName":"Maturation of protein E","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9684325","pathwayName":"Maturation of replicase proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694301","pathwayName":"Maturation of replicase proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9683686","pathwayName":"Maturation of spike protein","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694548","pathwayName":"Maturation of spike protein","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5662702","pathwayName":"Melanin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-174490","pathwayName":"Membrane binding and targetting of GAG proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2022377","pathwayName":"Metabolism of Angiotensinogen to Angiotensins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-196757","pathwayName":"Metabolism of folate and pterines","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2408550","pathwayName":"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5263617","pathwayName":"Metabolism of ingested MeSeO2H into MeSeH","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2408508","pathwayName":"Metabolism of ingested SeMet, Sec, MeSec into H2Se","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-380612","pathwayName":"Metabolism of serotonin","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-196071","pathwayName":"Metabolism of steroid hormones","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6806664","pathwayName":"Metabolism of vitamin K","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-425410","pathwayName":"Metal ion SLC transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-6799990","pathwayName":"Metal sequestration by antimicrobial proteins","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5689901","pathwayName":"Metalloprotease DUBs","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5661231","pathwayName":"Metallothioneins bind metals","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-1237112","pathwayName":"Methionine salvage pathway","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156581","pathwayName":"Methylation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-203927","pathwayName":"MicroRNA (miRNA) biogenesis","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9686347","pathwayName":"Microbial modulation of RIPK1-mediated regulated necrosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190840","pathwayName":"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-193993","pathwayName":"Mineralocorticoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-164516","pathwayName":"Minus-strand DNA synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5223345","pathwayName":"Miscellaneous transport and binding events","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5358606","pathwayName":"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5358565","pathwayName":"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-1369007","pathwayName":"Mitochondrial ABC transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-77289","pathwayName":"Mitochondrial Fatty Acid Beta-Oxidation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9836573","pathwayName":"Mitochondrial RNA degradation","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8949215","pathwayName":"Mitochondrial calcium ion transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-1362409","pathwayName":"Mitochondrial iron-sulfur cluster biogenesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9837999","pathwayName":"Mitochondrial protein degradation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1268020","pathwayName":"Mitochondrial protein import","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-379726","pathwayName":"Mitochondrial tRNA aminoacylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-163282","pathwayName":"Mitochondrial transcription initiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-163316","pathwayName":"Mitochondrial transcription termination","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5389840","pathwayName":"Mitochondrial translation elongation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5368286","pathwayName":"Mitochondrial translation initiation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5419276","pathwayName":"Mitochondrial translation termination","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-68877","pathwayName":"Mitotic Prometaphase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-68875","pathwayName":"Mitotic Prophase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9637628","pathwayName":"Modulation by Mtb of host immune system","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2129379","pathwayName":"Molecules associated with elastic fibres","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-947581","pathwayName":"Molybdenum cofactor biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1222449","pathwayName":"Mtb iron assimilation by chelation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-390648","pathwayName":"Muscarinic acetylcholine receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-975871","pathwayName":"MyD88 cascade initiated on plasma membrane","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5602498","pathwayName":"MyD88 deficiency (TLR2/4)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5602680","pathwayName":"MyD88 deficiency (TLR5)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-975155","pathwayName":"MyD88 dependent cascade initiated on endosome","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-166166","pathwayName":"MyD88-independent TLR4 cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-166058","pathwayName":"MyD88:MAL(TIRAP) cascade initiated on plasma membrane","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3785653","pathwayName":"Myoclonic epilepsy of Lafora","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-525793","pathwayName":"Myogenesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-975577","pathwayName":"N-Glycan antennae elongation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-532668","pathwayName":"N-glycan trimming in the ER and Calnexin/Calreticulin cycle","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-205025","pathwayName":"NADE modulates death signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-389542","pathwayName":"NADPH regeneration","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-375165","pathwayName":"NCAM signaling for neurite out-growth","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-419037","pathwayName":"NCAM1 interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-168333","pathwayName":"NEP/NS2 Interacts with the Cellular Export Machinery","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-933543","pathwayName":"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-209560","pathwayName":"NF-kB is activated and signals survival","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9818028","pathwayName":"NFE2L2 regulates pentose phosphate pathway genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818035","pathwayName":"NFE2L2 regulating ER-stress associated genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818032","pathwayName":"NFE2L2 regulating MDR associated enzymes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818025","pathwayName":"NFE2L2 regulating TCA cycle genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818027","pathwayName":"NFE2L2 regulating anti-oxidant/detoxification enzymes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818026","pathwayName":"NFE2L2 regulating inflammation associated genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9818030","pathwayName":"NFE2L2 regulating tumorigenic genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-205017","pathwayName":"NFG and proNGF binds to p75NTR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-167060","pathwayName":"NGF processing","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-187024","pathwayName":"NGF-independant TRKA activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9031628","pathwayName":"NGF-stimulated transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5676590","pathwayName":"NIK-->noncanonical NF-kB signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168638","pathwayName":"NOD1/2 Signaling Pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-203754","pathwayName":"NOSIP mediated eNOS trafficking","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-203641","pathwayName":"NOSTRIN mediated eNOS trafficking","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2122947","pathwayName":"NOTCH1 Intracellular Domain Regulates Transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2979096","pathwayName":"NOTCH2 Activation and Transmission of Signal to the Nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2197563","pathwayName":"NOTCH2 intracellular domain regulates transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013507","pathwayName":"NOTCH3 Activation and Transmission of Signal to the Nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013508","pathwayName":"NOTCH3 Intracellular Domain Regulates Transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013700","pathwayName":"NOTCH4 Activation and Transmission of Signal to the Nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013695","pathwayName":"NOTCH4 Intracellular Domain Regulates Transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9768919","pathwayName":"NPAS4 regulates expression of target genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-1368071","pathwayName":"NR1D1 (REV-ERBA) represses gene expression","topLevelPathway":"Circadian Clock","groupedPathway":"Tissue Function","topLevelOriginal":"Circadian Clock"}
{"pathwayId":"R-HSA-9632974","pathwayName":"NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9029558","pathwayName":"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9031528","pathwayName":"NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9623433","pathwayName":"NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9031525","pathwayName":"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9029569","pathwayName":"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-193648","pathwayName":"NRAGE signals death through JNK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-205043","pathwayName":"NRIF signals cell death from the nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-168276","pathwayName":"NS1 Mediated Effects on Host Pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9025046","pathwayName":"NTF3 activates NTRK2 (TRKB) signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9034013","pathwayName":"NTF3 activates NTRK3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9026357","pathwayName":"NTF4 activates NTRK2 (TRKB) signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9032759","pathwayName":"NTRK2 activates RAC1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9603505","pathwayName":"NTRK3 as a dependence receptor","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9717301","pathwayName":"NVP-TAE684-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-420597","pathwayName":"Nectin/Necl  trans heterodimerization","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-8951664","pathwayName":"Neddylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-167590","pathwayName":"Nef Mediated CD4 Down-regulation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-182218","pathwayName":"Nef Mediated CD8 Down-regulation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-164944","pathwayName":"Nef and signal transduction","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-164939","pathwayName":"Nef mediated downregulation of CD28 cell surface expression","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-164940","pathwayName":"Nef mediated downregulation of MHC class I complex cell surface expression","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5674499","pathwayName":"Negative feedback regulation of MAPK pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654726","pathwayName":"Negative regulation of FGFR1 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654727","pathwayName":"Negative regulation of FGFR2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654732","pathwayName":"Negative regulation of FGFR3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654733","pathwayName":"Negative regulation of FGFR4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9706369","pathwayName":"Negative regulation of FLT3","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5675221","pathwayName":"Negative regulation of MAPK pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6807004","pathwayName":"Negative regulation of MET activity","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9617324","pathwayName":"Negative regulation of NMDA receptor-mediated neuronal transmission","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9604323","pathwayName":"Negative regulation of NOTCH4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5368598","pathwayName":"Negative regulation of TCF-dependent signaling by DVL-interacting proteins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3772470","pathwayName":"Negative regulation of TCF-dependent signaling by WNT ligand antagonists","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8866904","pathwayName":"Negative regulation of activity of TFAP2 (AP-2) family transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-199418","pathwayName":"Negative regulation of the PI3K/AKT network","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-936440","pathwayName":"Negative regulators of DDX58/IFIH1 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-373753","pathwayName":"Nephrin family interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9831926","pathwayName":"Nephron development","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-418886","pathwayName":"Netrin mediated repulsion signals","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-373752","pathwayName":"Netrin-1 signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-6794361","pathwayName":"Neurexins and neuroligins","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-447043","pathwayName":"Neurofascin interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-194306","pathwayName":"Neurophilin interactions with VEGF and VEGFR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-112311","pathwayName":"Neurotransmitter clearance","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-112314","pathwayName":"Neurotransmitter receptors and postsynaptic signal transmission","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-112310","pathwayName":"Neurotransmitter release cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-197264","pathwayName":"Nicotinamide salvaging","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196807","pathwayName":"Nicotinate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-392154","pathwayName":"Nitric oxide stimulates guanylate cyclase","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-427413","pathwayName":"NoRC negatively regulates rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-3000171","pathwayName":"Non-integrin membrane-ECM interactions","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-9017802","pathwayName":"Noncanonical activation of NOTCH3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5693571","pathwayName":"Nonhomologous End-Joining (NHEJ)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-975957","pathwayName":"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-975956","pathwayName":"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-181430","pathwayName":"Norepinephrine Neurotransmitter Release Cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-350054","pathwayName":"Notch-HLH transcription pathway","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-447038","pathwayName":"NrCAM interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2980766","pathwayName":"Nuclear Envelope Breakdown","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-3301854","pathwayName":"Nuclear Pore Complex (NPC) Disassembly","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-383280","pathwayName":"Nuclear Receptor transcription pathway","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9759194","pathwayName":"Nuclear events mediated by NFE2L2","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9725371","pathwayName":"Nuclear events stimulated by ALK signaling in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-180746","pathwayName":"Nuclear import of Rev protein","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1251985","pathwayName":"Nuclear signaling by ERBB4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8956319","pathwayName":"Nucleotide catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5173105","pathwayName":"O-linked glycosylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-913709","pathwayName":"O-linked glycosylation of mucins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8983711","pathwayName":"OAS antiviral response","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9853506","pathwayName":"OGDH complex synthesizes succinyl-CoA from 2-OG","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-381753","pathwayName":"Olfactory Signaling Pathway","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-190704","pathwayName":"Oligomerization of connexins into connexons","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-2559585","pathwayName":"Oncogene Induced Senescence","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-111885","pathwayName":"Opioid Signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-419771","pathwayName":"Opsins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-389397","pathwayName":"Orexin and neuropeptides FF and QRFP bind to their respective receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-428643","pathwayName":"Organic anion transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-449836","pathwayName":"Other interleukin signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-416700","pathwayName":"Other semaphorin interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5689896","pathwayName":"Ovarian tumor domain proteases","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2559580","pathwayName":"Oxidative Stress Induced Senescence","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-1234176","pathwayName":"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-417957","pathwayName":"P2Y receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-141334","pathwayName":"PAOs oxidise polyamines to amines","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5651801","pathwayName":"PCNA-Dependent Long Patch Base Excision Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-4086400","pathwayName":"PCP/CE pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-389948","pathwayName":"PD-1 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-165160","pathwayName":"PDE3B signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9674428","pathwayName":"PDGFR mutants bind TKIs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9861559","pathwayName":"PDH complex synthesizes acetyl-CoA from PYR","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-210990","pathwayName":"PECAM1 interactions","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-381042","pathwayName":"PERK regulates gene expression","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-1483196","pathwayName":"PI and PC transport between ER and Golgi membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5654689","pathwayName":"PI-3K cascade:FGFR1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654695","pathwayName":"PI-3K cascade:FGFR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654710","pathwayName":"PI-3K cascade:FGFR3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654720","pathwayName":"PI-3K cascade:FGFR4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-109704","pathwayName":"PI3K Cascade","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1963642","pathwayName":"PI3K events in ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1250342","pathwayName":"PI3K events in ERBB4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-198203","pathwayName":"PI3K/AKT activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6811555","pathwayName":"PI5P Regulates TP53 Acetylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6811558","pathwayName":"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5205685","pathwayName":"PINK1-PRKN Mediated Mitophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-1257604","pathwayName":"PIP3 activates AKT signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5601884","pathwayName":"PIWI-interacting RNA (piRNA) biogenesis","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-163615","pathwayName":"PKA activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-164378","pathwayName":"PKA activation in glucagon signalling","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-111931","pathwayName":"PKA-mediated phosphorylation of CREB","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-163358","pathwayName":"PKA-mediated phosphorylation of key metabolic factors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3214841","pathwayName":"PKMTs methylate histone lysines","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-9833482","pathwayName":"PKR-mediated signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-112043","pathwayName":"PLC beta mediated events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-167021","pathwayName":"PLC-gamma1 signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1251932","pathwayName":"PLCG1 events in ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-110362","pathwayName":"POLB-Dependent Long Patch Base Excision Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-2892247","pathwayName":"POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2892245","pathwayName":"POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-163767","pathwayName":"PP2A-mediated dephosphorylation of key metabolic factors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1989781","pathwayName":"PPARA activates gene expression","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-212300","pathwayName":"PRC2 methylates histones and DNA","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8849474","pathwayName":"PTK6 Activates STAT3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849472","pathwayName":"PTK6 Down-Regulation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849473","pathwayName":"PTK6 Expression","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849470","pathwayName":"PTK6 Regulates Cell Cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849468","pathwayName":"PTK6 Regulates Proteins Involved in RNA Processing","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849471","pathwayName":"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8849469","pathwayName":"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8857538","pathwayName":"PTK6 promotes HIF1A stabilization","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-171306","pathwayName":"Packaging Of Telomere Ends","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-168303","pathwayName":"Packaging of Eight RNA Segments","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9753281","pathwayName":"Paracetamol ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-6802955","pathwayName":"Paradoxical activation of RAF signaling by kinase inactive BRAF","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-432047","pathwayName":"Passive transport by Aquaporins","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-167290","pathwayName":"Pausing and recovery of HIV elongation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167238","pathwayName":"Pausing and recovery of Tat-mediated HIV elongation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-71336","pathwayName":"Pentose phosphate pathway","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156902","pathwayName":"Peptide chain elongation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-209952","pathwayName":"Peptide hormone biosynthesis","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-375276","pathwayName":"Peptide ligand-binding receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-390918","pathwayName":"Peroxisomal lipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9033241","pathwayName":"Peroxisomal protein import","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-9664873","pathwayName":"Pexophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-5576892","pathwayName":"Phase 0 - rapid depolarisation","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-5576894","pathwayName":"Phase 1 - inactivation of fast Na+ channels","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-5576893","pathwayName":"Phase 2 - plateau phase","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-5576890","pathwayName":"Phase 3 - rapid repolarisation","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-5576886","pathwayName":"Phase 4 - resting membrane potential","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-211945","pathwayName":"Phase I - Functionalization of compounds","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8964208","pathwayName":"Phenylalanine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2160456","pathwayName":"Phenylketonuria","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8850843","pathwayName":"Phosphate bond hydrolysis by NTPDase proteins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2393930","pathwayName":"Phosphate bond hydrolysis by NUDT proteins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5654219","pathwayName":"Phospholipase C-mediated cascade: FGFR1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654221","pathwayName":"Phospholipase C-mediated cascade; FGFR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654227","pathwayName":"Phospholipase C-mediated cascade; FGFR3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654228","pathwayName":"Phospholipase C-mediated cascade; FGFR4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-202427","pathwayName":"Phosphorylation of CD3 and TCR zeta chains","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-176417","pathwayName":"Phosphorylation of Emi1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69200","pathwayName":"Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-170145","pathwayName":"Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-176412","pathwayName":"Phosphorylation of the APC/C","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5578768","pathwayName":"Physiological factors","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-75896","pathwayName":"Plasmalogen biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-75892","pathwayName":"Platelet Adhesion to exposed collagen","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-76009","pathwayName":"Platelet Aggregation (Plug Formation)","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-114608","pathwayName":"Platelet degranulation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-418346","pathwayName":"Platelet homeostasis","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-432142","pathwayName":"Platelet sensitization by LDL","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-164525","pathwayName":"Plus-strand DNA synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-156711","pathwayName":"Polo-like kinase mediated events","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174411","pathwayName":"Polymerase switching on the C-strand of the telomere","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-389977","pathwayName":"Post-chaperonin tubulin folding pathway","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-426496","pathwayName":"Post-transcriptional silencing by small RNAs","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-163125","pathwayName":"Post-translational modification: synthesis of GPI-anchored proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8957275","pathwayName":"Post-translational protein phosphorylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9615933","pathwayName":"Postmitotic nuclear pore complex (NPC) reformation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1296067","pathwayName":"Potassium transport channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9679191","pathwayName":"Potential therapeutics for SARS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1912420","pathwayName":"Pre-NOTCH Processing in Golgi","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1912408","pathwayName":"Pre-NOTCH Transcription and Translation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9757110","pathwayName":"Prednisone ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-389957","pathwayName":"Prefoldin mediated transfer of substrate  to CCT/TriC","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-196108","pathwayName":"Pregnenolone biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-112308","pathwayName":"Presynaptic depolarization and calcium channel opening","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-500657","pathwayName":"Presynaptic function of Kainate receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-5693616","pathwayName":"Presynaptic phase of homologous DNA pairing and strand exchange","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9636383","pathwayName":"Prevention of phagosomal-lysosomal fusion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-72203","pathwayName":"Processing of Capped Intron-Containing Pre-mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-5693607","pathwayName":"Processing of DNA double-strand break ends","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-77595","pathwayName":"Processing of Intronless Pre-mRNAs","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8949664","pathwayName":"Processing of SMDT1","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-174414","pathwayName":"Processive synthesis on the C-strand of the telomere","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1170546","pathwayName":"Prolactin receptor signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-70688","pathwayName":"Proline catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-71032","pathwayName":"Propionyl-CoA catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-392851","pathwayName":"Prostacyclin signalling through prostacyclin receptor","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-391908","pathwayName":"Prostanoid ligand receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9629569","pathwayName":"Protein hydroxylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9857492","pathwayName":"Protein lipoylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-433692","pathwayName":"Proton-coupled monocarboxylate transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-74259","pathwayName":"Purine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-73817","pathwayName":"Purine ribonucleoside monophosphate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-74217","pathwayName":"Purine salvage","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9660826","pathwayName":"Purinergic signaling in leishmaniasis infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-500753","pathwayName":"Pyrimidine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-73621","pathwayName":"Pyrimidine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-73614","pathwayName":"Pyrimidine salvage","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-71737","pathwayName":"Pyrophosphate hydrolysis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5620971","pathwayName":"Pyroptosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-70268","pathwayName":"Pyruvate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5365859","pathwayName":"RA biosynthesis pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8876198","pathwayName":"RAB GEFs exchange GTP for GDP on RABs","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-8873719","pathwayName":"RAB geranylgeranylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9013149","pathwayName":"RAC1 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013404","pathwayName":"RAC2 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013423","pathwayName":"RAC3 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5673000","pathwayName":"RAF activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-112409","pathwayName":"RAF-independent MAPK1/3 activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5673001","pathwayName":"RAF/MAP kinase cascade","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9648002","pathwayName":"RAS processing","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6802953","pathwayName":"RAS signaling downstream of NF1 loss-of-function variants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8853659","pathwayName":"RET signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5663220","pathwayName":"RHO GTPases Activate Formins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5668599","pathwayName":"RHO GTPases Activate NADPH Oxidases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5627117","pathwayName":"RHO GTPases Activate ROCKs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5666185","pathwayName":"RHO GTPases Activate Rhotekin and Rhophilins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5663213","pathwayName":"RHO GTPases Activate WASPs and WAVEs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5625900","pathwayName":"RHO GTPases activate CIT","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5626467","pathwayName":"RHO GTPases activate IQGAPs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5625970","pathwayName":"RHO GTPases activate KTN1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5627123","pathwayName":"RHO GTPases activate PAKs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5625740","pathwayName":"RHO GTPases activate PKNs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5627083","pathwayName":"RHO GTPases regulate CFTR trafficking","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8980692","pathwayName":"RHOA GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013026","pathwayName":"RHOB GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013422","pathwayName":"RHOBTB1 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013418","pathwayName":"RHOBTB2 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9706019","pathwayName":"RHOBTB3 ATPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013106","pathwayName":"RHOC GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013405","pathwayName":"RHOD GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9035034","pathwayName":"RHOF GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013408","pathwayName":"RHOG GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013407","pathwayName":"RHOH GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013409","pathwayName":"RHOJ GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013406","pathwayName":"RHOQ GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013425","pathwayName":"RHOT1 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013419","pathwayName":"RHOT2 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013420","pathwayName":"RHOU GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013424","pathwayName":"RHOV GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1810476","pathwayName":"RIP-mediated NFkB activation via ZBP1","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5213460","pathwayName":"RIPK1-mediated regulated necrosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-3214858","pathwayName":"RMTs methylate histone arginines","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-77075","pathwayName":"RNA Pol II CTD phosphorylation and interaction with CE","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-167160","pathwayName":"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-73772","pathwayName":"RNA Polymerase I Promoter Escape","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73728","pathwayName":"RNA Polymerase I Promoter Opening","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73762","pathwayName":"RNA Polymerase I Transcription Initiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73863","pathwayName":"RNA Polymerase I Transcription Termination","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-167162","pathwayName":"RNA Polymerase II HIV Promoter Escape","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-674695","pathwayName":"RNA Polymerase II Pre-transcription Events","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73776","pathwayName":"RNA Polymerase II Promoter Escape","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-75955","pathwayName":"RNA Polymerase II Transcription Elongation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-75953","pathwayName":"RNA Polymerase II Transcription Initiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-76042","pathwayName":"RNA Polymerase II Transcription Initiation And Promoter Clearance","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73779","pathwayName":"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73856","pathwayName":"RNA Polymerase II Transcription Termination","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-749476","pathwayName":"RNA Polymerase III Abortive And Retractive Initiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73780","pathwayName":"RNA Polymerase III Chain Elongation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-76061","pathwayName":"RNA Polymerase III Transcription Initiation From Type 1 Promoter","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-76066","pathwayName":"RNA Polymerase III Transcription Initiation From Type 2 Promoter","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-76071","pathwayName":"RNA Polymerase III Transcription Initiation From Type 3 Promoter","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73980","pathwayName":"RNA Polymerase III Transcription Termination","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6807505","pathwayName":"RNA polymerase II transcribes snRNA genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9696273","pathwayName":"RND1 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9696270","pathwayName":"RND2 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9696264","pathwayName":"RND3 GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9010642","pathwayName":"ROBO receptors bind AKAP5","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-1368082","pathwayName":"RORA activates gene expression","topLevelPathway":"Circadian Clock","groupedPathway":"Tissue Function","topLevelOriginal":"Circadian Clock"}
{"pathwayId":"R-HSA-1222556","pathwayName":"ROS and RNS production in phagocytes","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-444257","pathwayName":"RSK activation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-9833110","pathwayName":"RSV-host interactions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8877330","pathwayName":"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939243","pathwayName":"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8931987","pathwayName":"RUNX1 regulates estrogen receptor mediated transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8935964","pathwayName":"RUNX1 regulates expression of components of tight junctions","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8936459","pathwayName":"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939245","pathwayName":"RUNX1 regulates transcription of genes involved in BCR signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939256","pathwayName":"RUNX1 regulates transcription of genes involved in WNT signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939236","pathwayName":"RUNX1 regulates transcription of genes involved in differentiation of HSCs","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939242","pathwayName":"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939246","pathwayName":"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939247","pathwayName":"RUNX1 regulates transcription of genes involved in interleukin signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941326","pathwayName":"RUNX2 regulates bone development","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941284","pathwayName":"RUNX2 regulates chondrocyte maturation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941332","pathwayName":"RUNX2 regulates genes involved in cell migration","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941333","pathwayName":"RUNX2 regulates genes involved in differentiation of myeloid cells","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8940973","pathwayName":"RUNX2 regulates osteoblast differentiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8949275","pathwayName":"RUNX3 Regulates Immune Response and Cell Migration","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8952158","pathwayName":"RUNX3 regulates BCL2L11 (BIM) transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941855","pathwayName":"RUNX3 regulates CDKN1A transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941856","pathwayName":"RUNX3 regulates NOTCH signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8951911","pathwayName":"RUNX3 regulates RUNX1-mediated transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8951430","pathwayName":"RUNX3 regulates WNT signaling","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8951671","pathwayName":"RUNX3 regulates YAP1-mediated transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8951936","pathwayName":"RUNX3 regulates p14-ARF","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-392517","pathwayName":"Rap1 signalling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-442982","pathwayName":"Ras activation upon Ca2+ influx through NMDA receptor","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-975578","pathwayName":"Reactions specific to the complex N-glycan synthesis pathway","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8934903","pathwayName":"Receptor Mediated Mitophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-388844","pathwayName":"Receptor-type tyrosine-protein phosphatases","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-110330","pathwayName":"Recognition and association of DNA glycosylase with site containing an affected purine","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-110328","pathwayName":"Recognition and association of DNA glycosylase with site containing an affected pyrimidine","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-110314","pathwayName":"Recognition of DNA damage by PCNA-containing replication complex","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5693565","pathwayName":"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-380320","pathwayName":"Recruitment of NuMA to mitotic centrosomes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-380270","pathwayName":"Recruitment of mitotic centrosome proteins and complexes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-159418","pathwayName":"Recycling of bile acids and salts","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-72731","pathwayName":"Recycling of eIF2:GDP","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-437239","pathwayName":"Recycling pathway of L1","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8866376","pathwayName":"Reelin signalling pathway","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-193692","pathwayName":"Regulated proteolysis of p75NTR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3248023","pathwayName":"Regulation by TREX1","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3371378","pathwayName":"Regulation by c-FLIP","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-176408","pathwayName":"Regulation of APC/C activators between G1/S and early anaphase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-169911","pathwayName":"Regulation of Apoptosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-9708530","pathwayName":"Regulation of BACH1 activity","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9762292","pathwayName":"Regulation of CDH11 function","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9762293","pathwayName":"Regulation of CDH11 gene transcription","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9759811","pathwayName":"Regulation of CDH11 mRNA translation by microRNAs","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9764302","pathwayName":"Regulation of CDH19 Expression and Function","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-977606","pathwayName":"Regulation of Complement cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9617629","pathwayName":"Regulation of FOXO transcriptional activity by acetylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-4641263","pathwayName":"Regulation of FZD by ubiquitination","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-170822","pathwayName":"Regulation of Glucokinase by Glucokinase Regulatory Protein","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9707587","pathwayName":"Regulation of HMOX1 expression and activity","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-3371453","pathwayName":"Regulation of HSF1-mediated heat shock response","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-912694","pathwayName":"Regulation of IFNA/IFNB signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-877312","pathwayName":"Regulation of IFNG signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-381426","pathwayName":"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1433559","pathwayName":"Regulation of KIT signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9022692","pathwayName":"Regulation of MECP2 expression and activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9854909","pathwayName":"Regulation of MITF-M dependent genes involved in invasion","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9854907","pathwayName":"Regulation of MITF-M dependent genes involved in metabolism","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9825895","pathwayName":"Regulation of MITF-M-dependent genes involved in DNA damage repair and senescence","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9824594","pathwayName":"Regulation of MITF-M-dependent genes involved in apoptosis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9825892","pathwayName":"Regulation of MITF-M-dependent genes involved in cell cycle and proliferation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9857377","pathwayName":"Regulation of MITF-M-dependent genes involved in lysosome biogenesis and autophagy","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9824585","pathwayName":"Regulation of MITF-M-dependent genes involved in pigmentation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9758274","pathwayName":"Regulation of NF-kappa B signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9818749","pathwayName":"Regulation of NFE2L2 gene expression","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9768777","pathwayName":"Regulation of NPAS4 gene transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9768778","pathwayName":"Regulation of NPAS4 mRNA translation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-211728","pathwayName":"Regulation of PAK-2p34 activity by PS-GAP/RHG10","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-2565942","pathwayName":"Regulation of PLK1 Activity at G2/M Transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8943724","pathwayName":"Regulation of PTEN gene transcription","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8943723","pathwayName":"Regulation of PTEN mRNA translation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8948751","pathwayName":"Regulation of PTEN stability and activity","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5658442","pathwayName":"Regulation of RAS by GAPs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8934593","pathwayName":"Regulation of RUNX1 Expression and Activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8939902","pathwayName":"Regulation of RUNX2 expression and activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8941858","pathwayName":"Regulation of RUNX3 expression and activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9824878","pathwayName":"Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9828211","pathwayName":"Regulation of TBK1, IKKε-mediated activation of IRF3, IRF7 upon TLR3 ligation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5686938","pathwayName":"Regulation of TLR by endogenous ligand","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5357905","pathwayName":"Regulation of TNFR1 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6804758","pathwayName":"Regulation of TP53 Activity through Acetylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804759","pathwayName":"Regulation of TP53 Activity through Association with Co-factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804760","pathwayName":"Regulation of TP53 Activity through Methylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804756","pathwayName":"Regulation of TP53 Activity through Phosphorylation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804757","pathwayName":"Regulation of TP53 Degradation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804754","pathwayName":"Regulation of TP53 Expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-2029482","pathwayName":"Regulation of actin dynamics for phagocytic cup formation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-211733","pathwayName":"Regulation of activated PAK-2p34 by proteasome mediated degradation","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-1655829","pathwayName":"Regulation of cholesterol biosynthesis by SREBP (SREBF)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-428542","pathwayName":"Regulation of commissural axon pathfinding by SLIT and ROBO","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8985801","pathwayName":"Regulation of cortical dendrite branching","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-446388","pathwayName":"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9010553","pathwayName":"Regulation of expression of SLITs and ROBOs","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-191650","pathwayName":"Regulation of gap junction activity","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-1234158","pathwayName":"Regulation of gene expression by Hypoxia-inducible Factor","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-210745","pathwayName":"Regulation of gene expression in beta cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-210744","pathwayName":"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9634600","pathwayName":"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3134975","pathwayName":"Regulation of innate immune responses to cytosolic DNA","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-422356","pathwayName":"Regulation of insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-400206","pathwayName":"Regulation of lipid metabolism by PPARalpha","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9614399","pathwayName":"Regulation of localization of FOXO transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5675482","pathwayName":"Regulation of necroptotic cell death","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-350562","pathwayName":"Regulation of ornithine decarboxylase (ODC)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-204174","pathwayName":"Regulation of pyruvate dehydrogenase (PDH) complex","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9861718","pathwayName":"Regulation of pyruvate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-912631","pathwayName":"Regulation of signaling by CBL","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1433617","pathwayName":"Regulation of signaling by NODAL","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9627069","pathwayName":"Regulation of the apoptosome activity","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-350864","pathwayName":"Regulation of thyroid hormone activity","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-444821","pathwayName":"Relaxin receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-168298","pathwayName":"Release","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5362798","pathwayName":"Release of Hh-Np from the secreting cell","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111457","pathwayName":"Release of apoptotic factors from the mitochondria","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-159782","pathwayName":"Removal of aminoterminal propeptides from gamma-carboxylated proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-174437","pathwayName":"Removal of the Flap Intermediate from the C-strand","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9821993","pathwayName":"Replacement of protamines by nucleosomes in the male pronucleus","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9682706","pathwayName":"Replication of the SARS-CoV-1 genome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694686","pathwayName":"Replication of the SARS-CoV-2 genome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4641265","pathwayName":"Repression of WNT target genes","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9665250","pathwayName":"Resistance of ERBB2 KD mutants to AEE788","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665249","pathwayName":"Resistance of ERBB2 KD mutants to afatinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665251","pathwayName":"Resistance of ERBB2 KD mutants to lapatinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665246","pathwayName":"Resistance of ERBB2 KD mutants to neratinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665247","pathwayName":"Resistance of ERBB2 KD mutants to osimertinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665244","pathwayName":"Resistance of ERBB2 KD mutants to sapitinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665245","pathwayName":"Resistance of ERBB2 KD mutants to tesevatinib","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665233","pathwayName":"Resistance of ERBB2 KD mutants to trastuzumab","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-110373","pathwayName":"Resolution of AP sites via the multiple-nucleotide patch replacement pathway","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-110381","pathwayName":"Resolution of AP sites via the single-nucleotide replacement pathway","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-73933","pathwayName":"Resolution of Abasic Sites (AP sites)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5693568","pathwayName":"Resolution of D-loop Structures through Holliday Junction Intermediates","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5693554","pathwayName":"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-2500257","pathwayName":"Resolution of Sister Chromatid Cohesion","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-611105","pathwayName":"Respiratory electron transport","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9820960","pathwayName":"Respiratory syncytial virus (RSV) attachment and entry","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9834752","pathwayName":"Respiratory syncytial virus genome replication","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9828642","pathwayName":"Respiratory syncytial virus genome transcription","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9648895","pathwayName":"Response of EIF2AK1 (HRI) to heme deficiency","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9633012","pathwayName":"Response of EIF2AK4 (GCN2) to amino acid deficiency","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-76005","pathwayName":"Response to elevated platelet cytosolic Ca2+","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-2453864","pathwayName":"Retinoid cycle disease events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-177504","pathwayName":"Retrograde neurotrophin signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6811440","pathwayName":"Retrograde transport at the Trans-Golgi-Network","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-165054","pathwayName":"Rev-mediated nuclear export of HIV RNA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-73943","pathwayName":"Reversal of alkylation damage by DNA dioxygenases","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-1475029","pathwayName":"Reversible hydration of carbon dioxide","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9755088","pathwayName":"Ribavirin ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-72702","pathwayName":"Ribosomal scanning and start codon recognition","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-428890","pathwayName":"Role of ABL in ROBO-SLIT signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2730905","pathwayName":"Role of LAT2/NTAL/LAB on calcium mobilization","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-2029485","pathwayName":"Role of phospholipids in phagocytosis","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-418890","pathwayName":"Role of second messengers in netrin-1 signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9692916","pathwayName":"SARS-CoV-1 activates/modulates innate immune responses","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9735869","pathwayName":"SARS-CoV-1 modulates host translation machinery","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9692912","pathwayName":"SARS-CoV-1 targets PDZ proteins in cell-cell junction","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9735871","pathwayName":"SARS-CoV-1 targets host intracellular signalling and regulatory pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9692914","pathwayName":"SARS-CoV-1-host interactions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9692913","pathwayName":"SARS-CoV-1-mediated effects on programmed cell death","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9705671","pathwayName":"SARS-CoV-2 activates/modulates innate and adaptive immune responses","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9754560","pathwayName":"SARS-CoV-2 modulates autophagy","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9754678","pathwayName":"SARS-CoV-2 modulates host translation machinery","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9705677","pathwayName":"SARS-CoV-2 targets PDZ proteins in cell-cell junction","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9755779","pathwayName":"SARS-CoV-2 targets host intracellular signalling and regulatory pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-187577","pathwayName":"SCF(Skp2)-mediated degradation of p27/p21","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174113","pathwayName":"SCF-beta-TrCP mediated degradation of Emi1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-373756","pathwayName":"SDK interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-399955","pathwayName":"SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5654688","pathwayName":"SHC-mediated cascade:FGFR1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654699","pathwayName":"SHC-mediated cascade:FGFR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654704","pathwayName":"SHC-mediated cascade:FGFR3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654719","pathwayName":"SHC-mediated cascade:FGFR4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2428933","pathwayName":"SHC-related events triggered by IGF1R","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-180336","pathwayName":"SHC1 events in EGFR signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1250196","pathwayName":"SHC1 events in ERBB2 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1250347","pathwayName":"SHC1 events in ERBB4 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9726840","pathwayName":"SHOC2 M1731 mutant abolishes MRAS complex function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-427359","pathwayName":"SIRT1 negatively regulates rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-77588","pathwayName":"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-111367","pathwayName":"SLBP independent Processing of Histone Pre-mRNAs","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8985586","pathwayName":"SLIT2:ROBO1 increases RHOA activity","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-111463","pathwayName":"SMAC (DIABLO) binds to IAPs","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-111464","pathwayName":"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-111469","pathwayName":"SMAC, XIAP-regulated apoptotic response","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-3304356","pathwayName":"SMAD2/3 Phosphorylation Motif Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-112412","pathwayName":"SOS-mediated signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1799339","pathwayName":"SRP-dependent cotranslational protein targeting to membrane","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9701898","pathwayName":"STAT3 nuclear events downstream of ALK signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9645135","pathwayName":"STAT5 Activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9702518","pathwayName":"STAT5 activation downstream of FLT3 ITD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3249367","pathwayName":"STAT6-mediated induction of chemokines","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1834941","pathwayName":"STING mediated induction of host immune responses","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-3065676","pathwayName":"SUMO is conjugated to E1 (UBA2:SAE1)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3065678","pathwayName":"SUMO is transferred from E1 to E2 (UBE2I, UBC9)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3108214","pathwayName":"SUMOylation of DNA damage response and repair proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4655427","pathwayName":"SUMOylation of DNA methylation proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4615885","pathwayName":"SUMOylation of DNA replication proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4570464","pathwayName":"SUMOylation of RNA binding proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4085377","pathwayName":"SUMOylation of SUMOylation proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4551638","pathwayName":"SUMOylation of chromatin organization proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4755510","pathwayName":"SUMOylation of immune response proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-4090294","pathwayName":"SUMOylation of intracellular receptors","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9793242","pathwayName":"SUMOylation of nuclear envelope proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3899300","pathwayName":"SUMOylation of transcription cofactors","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3232118","pathwayName":"SUMOylation of transcription factors","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3232142","pathwayName":"SUMOylation of ubiquitinylation proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3000480","pathwayName":"Scavenging by Class A Receptors","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-3000471","pathwayName":"Scavenging by Class B Receptors","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-3000484","pathwayName":"Scavenging by Class F Receptors","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-3000497","pathwayName":"Scavenging by Class H Receptors","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-2168880","pathwayName":"Scavenging of heme from plasma","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-9668328","pathwayName":"Sealing of the nuclear envelope (NE) by ESCRT-III","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2408522","pathwayName":"Selenoamino acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2408557","pathwayName":"Selenocysteine synthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-399954","pathwayName":"Sema3A PAK dependent Axon repulsion","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-416572","pathwayName":"Sema4D induced cell migration and growth-cone collapse","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-416550","pathwayName":"Sema4D mediated inhibition of cell attachment and migration","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2559582","pathwayName":"Senescence-Associated Secretory Phenotype (SASP)","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-5693548","pathwayName":"Sensing of DNA Double Strand Breaks","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9730628","pathwayName":"Sensory perception of salty taste","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9717207","pathwayName":"Sensory perception of sweet, bitter, and umami (glutamate) taste","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9662360","pathwayName":"Sensory processing of sound by inner hair cells of the cochlea","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9662361","pathwayName":"Sensory processing of sound by outer hair cells of the cochlea","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-2467813","pathwayName":"Separation of Sister Chromatids","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-977347","pathwayName":"Serine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-181429","pathwayName":"Serotonin Neurotransmitter Release Cycle","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-209931","pathwayName":"Serotonin and melatonin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-380615","pathwayName":"Serotonin clearance from the synaptic cleft","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-390666","pathwayName":"Serotonin receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-4085001","pathwayName":"Sialic acid metabolism","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-74749","pathwayName":"Signal attenuation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-391160","pathwayName":"Signal regulatory protein family interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-445144","pathwayName":"Signal transduction by L1","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-201556","pathwayName":"Signaling by ALK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9725370","pathwayName":"Signaling by ALK fusions and activated point mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1502540","pathwayName":"Signaling by Activin","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-201451","pathwayName":"Signaling by BMP","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6802952","pathwayName":"Signaling by BRAF and RAF1 fusions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9680350","pathwayName":"Signaling by CSF1 (M-CSF) in myeloid cells","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9674555","pathwayName":"Signaling by CSF3 (G-CSF)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-177929","pathwayName":"Signaling by EGFR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1227986","pathwayName":"Signaling by ERBB2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9665348","pathwayName":"Signaling by ERBB2 ECD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9664565","pathwayName":"Signaling by ERBB2 KD Mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9665686","pathwayName":"Signaling by ERBB2 TMD/JMD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1236394","pathwayName":"Signaling by ERBB4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9006335","pathwayName":"Signaling by Erythropoietin","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1839120","pathwayName":"Signaling by FGFR1 amplification mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5655302","pathwayName":"Signaling by FGFR1 in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8851708","pathwayName":"Signaling by FGFR2 IIIa TM","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2023837","pathwayName":"Signaling by FGFR2 amplification mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8853333","pathwayName":"Signaling by FGFR2 fusions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5655253","pathwayName":"Signaling by FGFR2 in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8853334","pathwayName":"Signaling by FGFR3 fusions in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5655332","pathwayName":"Signaling by FGFR3 in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5655291","pathwayName":"Signaling by FGFR4 in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9703648","pathwayName":"Signaling by FLT3 ITD and TKD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9703465","pathwayName":"Signaling by FLT3 fusion proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5339716","pathwayName":"Signaling by GSK3beta mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2028269","pathwayName":"Signaling by Hippo","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-74752","pathwayName":"Signaling by Insulin receptor","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9842663","pathwayName":"Signaling by LTK","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9842640","pathwayName":"Signaling by LTK in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2586552","pathwayName":"Signaling by Leptin","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9652169","pathwayName":"Signaling by MAP2K mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8852405","pathwayName":"Signaling by MST1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1181150","pathwayName":"Signaling by NODAL","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9034015","pathwayName":"Signaling by NTRK3 (TRKC)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-186797","pathwayName":"Signaling by PDGF","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9673770","pathwayName":"Signaling by PDGFRA extracellular domain mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673767","pathwayName":"Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9656223","pathwayName":"Signaling by RAF1 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9753510","pathwayName":"Signaling by RAS GAP mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9753512","pathwayName":"Signaling by RAS GTPase mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5340588","pathwayName":"Signaling by RNF43 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-376176","pathwayName":"Signaling by ROBO receptors","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5362517","pathwayName":"Signaling by Retinoic Acid","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1433557","pathwayName":"Signaling by SCF-KIT","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2404192","pathwayName":"Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-194138","pathwayName":"Signaling by VEGF","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1839122","pathwayName":"Signaling by activated point mutants of FGFR1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1839130","pathwayName":"Signaling by activated point mutants of FGFR3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1839117","pathwayName":"Signaling by cytosolic FGFR1 fusion mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673766","pathwayName":"Signaling by cytosolic PDGFRA and PDGFRB fusion proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9680187","pathwayName":"Signaling by extracellular domain mutants of KIT","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6802948","pathwayName":"Signaling by high-kinase activity BRAF mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9669935","pathwayName":"Signaling by juxtamembrane domain KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673768","pathwayName":"Signaling by membrane-tethered fusions of PDGFRA or PDGFRB","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6802946","pathwayName":"Signaling by moderate kinase activity BRAF mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9670439","pathwayName":"Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8853336","pathwayName":"Signaling by plasma membrane FGFR1 fusions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9649948","pathwayName":"Signaling downstream of RAS mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167044","pathwayName":"Signalling to RAS","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-198745","pathwayName":"Signalling to STAT3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-187706","pathwayName":"Signalling to p38 via RIT and RIN","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-426486","pathwayName":"Small interfering RNA (siRNA) biogenesis","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-445355","pathwayName":"Smooth Muscle Contraction","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-9824272","pathwayName":"Somitogenesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9827857","pathwayName":"Specification of primordial germ cells","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-9834899","pathwayName":"Specification of the neural plate border","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-1300642","pathwayName":"Sperm Motility And Taxes","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-9845614","pathwayName":"Sphingolipid catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660661","pathwayName":"Sphingolipid de novo biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1295596","pathwayName":"Spry regulation of FGF signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-69541","pathwayName":"Stabilization of p53","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-211736","pathwayName":"Stimulation of the cell death response by PAK-2p34","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-2672351","pathwayName":"Stimuli-sensing channels","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-390522","pathwayName":"Striated Muscle Contraction","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-1614517","pathwayName":"Sulfide oxidation to sulfate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1614635","pathwayName":"Sulfur amino acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9635465","pathwayName":"Suppression of apoptosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9636569","pathwayName":"Suppression of autophagy","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5683826","pathwayName":"Surfactant metabolism","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8849932","pathwayName":"Synaptic adhesion-like molecules","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-3000170","pathwayName":"Syndecan interactions","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-171286","pathwayName":"Synthesis and processing of ENV and VPU","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2142712","pathwayName":"Synthesis of 12-eicosatetraenoic acid derivatives","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2142770","pathwayName":"Synthesis of 15-eicosatetraenoic acid derivatives","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2142688","pathwayName":"Synthesis of 5-eicosatetraenoic acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446199","pathwayName":"Synthesis of Dolichyl-phosphate","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2142696","pathwayName":"Synthesis of Hepoxilins (HX) and Trioxilins (TrX)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855183","pathwayName":"Synthesis of IP2, IP, and Ins in the cytosol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855204","pathwayName":"Synthesis of IP3 and IP4 in the cytosol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77111","pathwayName":"Synthesis of Ketone Bodies","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2142691","pathwayName":"Synthesis of Leukotrienes (LT) and Eoxins (EX)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2142700","pathwayName":"Synthesis of Lipoxins (LX)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483166","pathwayName":"Synthesis of PA","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483191","pathwayName":"Synthesis of PC","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483213","pathwayName":"Synthesis of PE","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483226","pathwayName":"Synthesis of PI","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483248","pathwayName":"Synthesis of PIPs at the ER membrane","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660514","pathwayName":"Synthesis of PIPs at the Golgi membrane","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660516","pathwayName":"Synthesis of PIPs at the early endosome membrane","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660517","pathwayName":"Synthesis of PIPs at the late endosome membrane","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660499","pathwayName":"Synthesis of PIPs at the plasma membrane","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8847453","pathwayName":"Synthesis of PIPs in the nucleus","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2162123","pathwayName":"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446210","pathwayName":"Synthesis of UDP-N-acetyl-glucosamine","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8866652","pathwayName":"Synthesis of active ubiquitin: roles of E1 and E2 enzymes","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-192105","pathwayName":"Synthesis of bile acids and bile salts","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-193807","pathwayName":"Synthesis of bile acids and bile salts via 27-hydroxycholesterol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-193368","pathwayName":"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5358493","pathwayName":"Synthesis of diphthamide-EEF2","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-162699","pathwayName":"Synthesis of dolichyl-phosphate mannose","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2142670","pathwayName":"Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-162710","pathwayName":"Synthesis of glycosylphosphatidylinositol (GPI)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1855167","pathwayName":"Synthesis of pyrophosphates in the cytosol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6782861","pathwayName":"Synthesis of wybutosine at G37 of tRNA(Phe)","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-422085","pathwayName":"Synthesis, secretion, and deacylation of Ghrelin","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-381771","pathwayName":"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-400511","pathwayName":"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-445989","pathwayName":"TAK1-dependent IKK and NF-kappa-B activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6791462","pathwayName":"TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6791055","pathwayName":"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8854214","pathwayName":"TBC/RABGAPs","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-201681","pathwayName":"TCF dependent signaling in response to WNT","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5221030","pathwayName":"TET1,2,3 and TDG demethylate DNA","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8866911","pathwayName":"TFAP2 (AP-2) family regulates transcription of cell cycle factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8866910","pathwayName":"TFAP2 (AP-2) family regulates transcription of growth factors and their receptors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8866906","pathwayName":"TFAP2 (AP-2) family regulates transcription of other transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8869496","pathwayName":"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-2173789","pathwayName":"TGF-beta receptor signaling activates SMADs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2173791","pathwayName":"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3656532","pathwayName":"TGFBR1 KD Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656535","pathwayName":"TGFBR1 LBD Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3645790","pathwayName":"TGFBR2 Kinase Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3642279","pathwayName":"TGFBR2 MSI Frameshift Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5602566","pathwayName":"TICAM1 deficiency - HSE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168927","pathwayName":"TICAM1, RIP1-mediated IKK complex recruitment","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9014325","pathwayName":"TICAM1,TRAF6-dependent induction of TAK1 complex","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9013973","pathwayName":"TICAM1-dependent activation of IRF3/IRF7","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9013957","pathwayName":"TLR3-mediated TICAM1-dependent programmed cell death","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5676594","pathwayName":"TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-75893","pathwayName":"TNF signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5357956","pathwayName":"TNFR1-induced NF-kappa-B signaling pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5357786","pathwayName":"TNFR1-induced proapoptotic signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5626978","pathwayName":"TNFR1-mediated ceramide production","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5668541","pathwayName":"TNFR2 non-canonical NF-kB pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5669034","pathwayName":"TNFs bind their physiological receptors","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5628897","pathwayName":"TP53 Regulates Metabolic Genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6803207","pathwayName":"TP53 Regulates Transcription of Caspase Activators and Caspases","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6796648","pathwayName":"TP53 Regulates Transcription of DNA Repair Genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6803211","pathwayName":"TP53 Regulates Transcription of Death Receptors and Ligands","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6803204","pathwayName":"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804116","pathwayName":"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804114","pathwayName":"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6804115","pathwayName":"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6803205","pathwayName":"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5602571","pathwayName":"TRAF3 deficiency - HSE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-918233","pathwayName":"TRAF3-dependent IRF activation pathway","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-933541","pathwayName":"TRAF6 mediated IRF7 activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-975110","pathwayName":"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-933542","pathwayName":"TRAF6 mediated NF-kB activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-975138","pathwayName":"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-937072","pathwayName":"TRAF6-mediated induction of TAK1 complex within TLR4 complex","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-75158","pathwayName":"TRAIL  signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2562578","pathwayName":"TRIF-mediated programmed cell death","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-187042","pathwayName":"TRKA activation by NGF","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3295583","pathwayName":"TRP channels","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-1299503","pathwayName":"TWIK related potassium channel (TREK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1299361","pathwayName":"TWIK-related alkaline pH activated K+ channel (TALK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1299344","pathwayName":"TWIK-related spinal cord K+ channel (TRESK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1299316","pathwayName":"TWIK-releated acid-sensitive K+ channel (TASK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-380095","pathwayName":"Tachykinin receptors bind tachykinins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1299308","pathwayName":"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1299287","pathwayName":"Tandem pore domain halothane-inhibited K+ channel (THIK)","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-167243","pathwayName":"Tat-mediated HIV elongation arrest and recovery","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167246","pathwayName":"Tat-mediated elongation of the HIV-1 transcript","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-174417","pathwayName":"Telomere C-strand (Lagging Strand) Synthesis","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-174430","pathwayName":"Telomere C-strand synthesis initiation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-171319","pathwayName":"Telomere Extension By Telomerase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-166665","pathwayName":"Terminal pathway of complement","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5656169","pathwayName":"Termination of translesion DNA synthesis","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-1474151","pathwayName":"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-844615","pathwayName":"The AIM2 inflammasome","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-844623","pathwayName":"The IPAF inflammasome","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-844455","pathwayName":"The NLRP1 inflammasome","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-844456","pathwayName":"The NLRP3 inflammasome","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1663150","pathwayName":"The activation of arylsulfatases","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2453902","pathwayName":"The canonical retinoid cycle in rods (twilight vision)","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-167826","pathwayName":"The fatty acid cycling model","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-167827","pathwayName":"The proton buffering model","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2187335","pathwayName":"The retinoid cycle in cones (daylight vision)","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-8852276","pathwayName":"The role of GTSE1 in G2/M progression after G2 checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8849175","pathwayName":"Threonine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-456926","pathwayName":"Thrombin signalling through proteinase activated receptors (PARs)","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-428930","pathwayName":"Thromboxane signalling through TP receptor","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-209968","pathwayName":"Thyroxine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-210993","pathwayName":"Tie2 Signaling","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-420029","pathwayName":"Tight junction interactions","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-1222538","pathwayName":"Tolerance by Mtb to nitric oxide produced by macrophages","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1222387","pathwayName":"Tolerance of reactive oxygen produced by macrophages","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168142","pathwayName":"Toll Like Receptor 10 (TLR10) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168164","pathwayName":"Toll Like Receptor 3 (TLR3) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-166016","pathwayName":"Toll Like Receptor 4 (TLR4) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168176","pathwayName":"Toll Like Receptor 5 (TLR5) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168181","pathwayName":"Toll Like Receptor 7/8 (TLR7/8) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168138","pathwayName":"Toll Like Receptor 9 (TLR9) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168179","pathwayName":"Toll Like Receptor TLR1:TLR2 Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168188","pathwayName":"Toll Like Receptor TLR6:TLR2 Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5250968","pathwayName":"Toxicity of botulinum toxin type A (botA)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250958","pathwayName":"Toxicity of botulinum toxin type B (botB)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250971","pathwayName":"Toxicity of botulinum toxin type C (botC)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250955","pathwayName":"Toxicity of botulinum toxin type D (botD)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250992","pathwayName":"Toxicity of botulinum toxin type E (botE)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250981","pathwayName":"Toxicity of botulinum toxin type F (botF)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250989","pathwayName":"Toxicity of botulinum toxin type G (botG)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250982","pathwayName":"Toxicity of tetanus toxin (tetX)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1679131","pathwayName":"Trafficking and processing of endosomal TLR","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-399719","pathwayName":"Trafficking of AMPA receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-416993","pathwayName":"Trafficking of GluR2-containing AMPA receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-5624138","pathwayName":"Trafficking of myristoylated proteins to the cilium","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-1362277","pathwayName":"Transcription of E2F targets under negative control by DREAM complex","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1362300","pathwayName":"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9682708","pathwayName":"Transcription of SARS-CoV-1 sgRNAs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694786","pathwayName":"Transcription of SARS-CoV-2 sgRNAs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167172","pathwayName":"Transcription of the HIV genome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6781827","pathwayName":"Transcription-Coupled Nucleotide Excision Repair (TC-NER)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-69895","pathwayName":"Transcriptional  activation of  cell cycle inhibitor p21","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8953750","pathwayName":"Transcriptional Regulation by E2F6","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8986944","pathwayName":"Transcriptional Regulation by MECP2","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8853884","pathwayName":"Transcriptional Regulation by VENTX","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-2151201","pathwayName":"Transcriptional activation of mitochondrial biogenesis","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-9856649","pathwayName":"Transcriptional and post-translational regulation of MITF-M expression and activity","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8878166","pathwayName":"Transcriptional regulation by RUNX2","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5578749","pathwayName":"Transcriptional regulation by small RNAs","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8864260","pathwayName":"Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9844594","pathwayName":"Transcriptional regulation of brown and beige adipocyte differentiation by EBF2","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9616222","pathwayName":"Transcriptional regulation of granulopoiesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-452723","pathwayName":"Transcriptional regulation of pluripotent stem cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9690406","pathwayName":"Transcriptional regulation of testis differentiation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-381340","pathwayName":"Transcriptional regulation of white adipocyte differentiation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-166020","pathwayName":"Transfer of LPS from LBP carrier to CD14","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-917977","pathwayName":"Transferrin endocytosis and recycling","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-72649","pathwayName":"Translation initiation complex formation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9727281","pathwayName":"Translation of Accessory Proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9679504","pathwayName":"Translation of Replicase and Assembly of the Replication Transcription Complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694676","pathwayName":"Translation of Replicase and Assembly of the Replication Transcription Complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-110320","pathwayName":"Translesion Synthesis by POLH","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5656121","pathwayName":"Translesion synthesis by POLI","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5655862","pathwayName":"Translesion synthesis by POLK","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-110312","pathwayName":"Translesion synthesis by REV1","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-1445148","pathwayName":"Translocation of SLC2A4 (GLUT4) to the plasma membrane","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-202430","pathwayName":"Translocation of ZAP-70 to Immunological synapse","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168874","pathwayName":"Transport of HA trimer, NA tetramer and M2 tetramer from the endoplasmic reticulum to the Golgi Apparatus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-159231","pathwayName":"Transport of Mature mRNA Derived from an Intronless Transcript","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-159236","pathwayName":"Transport of Mature mRNA derived from an Intron-Containing Transcript","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9758890","pathwayName":"Transport of RCbl within the body","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-168271","pathwayName":"Transport of Ribonucleoproteins into the Host Nucleus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190872","pathwayName":"Transport of connexons to the plasma membrane","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-804914","pathwayName":"Transport of fatty acids","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-159763","pathwayName":"Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-432030","pathwayName":"Transport of glycerol from adipocytes to the liver by Aquaporins","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-83936","pathwayName":"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-727802","pathwayName":"Transport of nucleotide sugars","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-879518","pathwayName":"Transport of organic anions","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-159230","pathwayName":"Transport of the SLBP Dependant Mature mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-159227","pathwayName":"Transport of the SLBP independent Mature mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-425397","pathwayName":"Transport of vitamins, nucleosides, and related molecules","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-948021","pathwayName":"Transport to the Golgi and subsequent modification","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-75109","pathwayName":"Triglyceride biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-163560","pathwayName":"Triglyceride catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-450513","pathwayName":"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-5467348","pathwayName":"Truncations of AMER1 destabilize the destruction complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-71240","pathwayName":"Tryptophan catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446107","pathwayName":"Type I hemidesmosome assembly","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-8963684","pathwayName":"Tyrosine catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5689603","pathwayName":"UCH proteinases","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5689880","pathwayName":"Ub-specific processing proteases","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2142789","pathwayName":"Ubiquinol biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-69601","pathwayName":"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-75815","pathwayName":"Ubiquitin-dependent degradation of Cyclin D","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-438066","pathwayName":"Unblocking of NMDA receptors, glutamate binding and activation","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-162585","pathwayName":"Uncoating of the HIV Virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168336","pathwayName":"Uncoating of the Influenza Virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5210891","pathwayName":"Uptake and function of anthrax toxins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5336415","pathwayName":"Uptake and function of diphtheria toxin","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9758881","pathwayName":"Uptake of dietary cobalamins into enterocytes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-70635","pathwayName":"Urea cycle","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-77108","pathwayName":"Utilization of Ketone Bodies","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-195399","pathwayName":"VEGF binds to VEGFR leading to receptor dimerization","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-194313","pathwayName":"VEGF ligand-receptor interactions","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-4420097","pathwayName":"VEGFA-VEGFR2 Pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5218921","pathwayName":"VEGFR2 mediated cell proliferation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5218920","pathwayName":"VEGFR2 mediated vascular permeability","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8866423","pathwayName":"VLDL assembly","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964046","pathwayName":"VLDL clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8866427","pathwayName":"VLDLR internalisation and degradation","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-432040","pathwayName":"Vasopressin regulates renal water homeostasis via Aquaporins","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-388479","pathwayName":"Vasopressin-like receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-180585","pathwayName":"Vif-mediated degradation of APOBEC3G","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168325","pathwayName":"Viral Messenger RNA Synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168330","pathwayName":"Viral RNP Complexes in the Host Cell Nucleus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-192823","pathwayName":"Viral mRNA Translation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694322","pathwayName":"Virion Assembly and Release","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9679509","pathwayName":"Virion Assembly and Release","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-196819","pathwayName":"Vitamin B1 (thiamin) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196843","pathwayName":"Vitamin B2 (riboflavin) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-199220","pathwayName":"Vitamin B5 (pantothenate) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-964975","pathwayName":"Vitamin B6 activation to pyridoxal phosphate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196836","pathwayName":"Vitamin C (ascorbate) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196791","pathwayName":"Vitamin D (calciferol) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8877627","pathwayName":"Vitamin E","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1296072","pathwayName":"Voltage gated Potassium channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-180897","pathwayName":"Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-180910","pathwayName":"Vpr-mediated nuclear import of PICs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-180534","pathwayName":"Vpu mediated degradation of CD4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5620916","pathwayName":"VxPx cargo-targeting to cilium","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-3238698","pathwayName":"WNT ligand biogenesis and trafficking","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-201688","pathwayName":"WNT mediated activation of DVL","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9673324","pathwayName":"WNT5:FZD7-mediated leishmania damping","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5140745","pathwayName":"WNT5A-dependent internalization of FZD2, FZD5 and ROR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5099900","pathwayName":"WNT5A-dependent internalization of FZD4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5545619","pathwayName":"XAV939 stabilizes AXIN","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-211981","pathwayName":"Xenobiotics","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2032785","pathwayName":"YAP1- and WWTR1 (TAZ)-stimulated gene expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9820865","pathwayName":"Z-decay: degradation of maternal mRNAs by zygotically expressed factors","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-1606322","pathwayName":"ZBP1(DAI) mediated induction of type I IFNs","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-435368","pathwayName":"Zinc efflux and compartmentalization by the SLC30 family","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9819196","pathwayName":"Zygotic genome activation (ZGA)","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-450302","pathwayName":"activated TAK1 mediates p38 MAPK activation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9717316","pathwayName":"alectinib-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2046106","pathwayName":"alpha-linolenic acid (ALA) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1307965","pathwayName":"betaKlotho-mediated ligand binding","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9717319","pathwayName":"brigatinib-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-418457","pathwayName":"cGMP effects","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-192869","pathwayName":"cRNA Synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9717323","pathwayName":"ceritinib-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702581","pathwayName":"crenolanib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9717326","pathwayName":"crizotinib-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-203615","pathwayName":"eNOS activation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9702590","pathwayName":"gilteritinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702596","pathwayName":"lestaurtinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702998","pathwayName":"linifanib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9717329","pathwayName":"lorlatinib-resistant ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-72187","pathwayName":"mRNA 3'-end processing","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-72086","pathwayName":"mRNA Capping","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-72200","pathwayName":"mRNA Editing: C to U Conversion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-72163","pathwayName":"mRNA Splicing - Major Pathway","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-72165","pathwayName":"mRNA Splicing - Minor Pathway","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-429958","pathwayName":"mRNA decay by 3' to 5' exoribonuclease","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-430039","pathwayName":"mRNA decay by 5' to 3' exoribonuclease","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-166208","pathwayName":"mTORC1-mediated signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9702600","pathwayName":"midostaurin-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-77288","pathwayName":"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-171007","pathwayName":"p38MAPK events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-69563","pathwayName":"p53-Dependent G1 DNA Damage Response","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-193670","pathwayName":"p75NTR negatively regulates cell cycle via SC1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-209543","pathwayName":"p75NTR recruits signalling complexes","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-111995","pathwayName":"phospho-PLA2 pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6793080","pathwayName":"rRNA modification in the mitochondrion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-6790901","pathwayName":"rRNA modification in the nucleus and cytosol","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8868766","pathwayName":"rRNA processing in the mitochondrion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9702577","pathwayName":"semaxanib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-191859","pathwayName":"snRNP Assembly","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-2033515","pathwayName":"t(4;14) translocations of FGFR3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6787450","pathwayName":"tRNA modification in the mitochondrion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-6782315","pathwayName":"tRNA modification in the nucleus and cytosol","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-6785470","pathwayName":"tRNA processing in the mitochondrion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-6784531","pathwayName":"tRNA processing in the nucleus","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9708296","pathwayName":"tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9703009","pathwayName":"tamatinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-199992","pathwayName":"trans-Golgi Network Vesicle Budding","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-192814","pathwayName":"vRNA Synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-192905","pathwayName":"vRNP Assembly","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619084","pathwayName":"ABC transporter disorders","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-198323","pathwayName":"AKT phosphorylates targets in the cytosol","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-198693","pathwayName":"AKT phosphorylates targets in the nucleus","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-211163","pathwayName":"AKT-mediated inactivation of FOXO1A","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-5467333","pathwayName":"APC truncation mutants are not K63 polyubiquitinated","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-174143","pathwayName":"APC/C-mediated degradation of cell cycle proteins","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-179419","pathwayName":"APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2161522","pathwayName":"Abacavir ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-9659787","pathwayName":"Aberrant regulation of mitotic G1/S transition in cancer due to RB1 defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9687139","pathwayName":"Aberrant regulation of mitotic cell cycle due to RB1 defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-156582","pathwayName":"Acetylation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-181431","pathwayName":"Acetylcholine binding and downstream events","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-176814","pathwayName":"Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-114452","pathwayName":"Activation of BH3-only proteins","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-991365","pathwayName":"Activation of GABAB receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-5619507","pathwayName":"Activation of HOX genes during differentiation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-442755","pathwayName":"Activation of NMDA receptors and postsynaptic events","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-187015","pathwayName":"Activation of TRKA receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-451326","pathwayName":"Activation of kainate receptors upon glutamate binding","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1280218","pathwayName":"Adaptive Immune System","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9843745","pathwayName":"Adipogenesis","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-1428517","pathwayName":"Aerobic respiration and respiratory electron transport","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-351143","pathwayName":"Agmatine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9730737","pathwayName":"Alkylating DNA damage induced by chemotherapeutic drugs","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9006821","pathwayName":"Alternative Lengthening of Telomeres (ALT)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-140179","pathwayName":"Amine Oxidase reactions","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-156587","pathwayName":"Amino Acid conjugation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-141424","pathwayName":"Amplification of signal from the kinetochores","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9662851","pathwayName":"Anti-inflammatory response favouring Leishmania parasite infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1236975","pathwayName":"Antigen processing-Cross presentation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1169410","pathwayName":"Antiviral mechanism by IFN-stimulated genes","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-109581","pathwayName":"Apoptosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-445717","pathwayName":"Aquaporin-mediated transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-211957","pathwayName":"Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-422475","pathwayName":"Axon guidance","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9824439","pathwayName":"Bacterial Infection Pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-73884","pathwayName":"Base Excision Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-73929","pathwayName":"Base-Excision Repair, AP Site Formation","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-3858494","pathwayName":"Beta-catenin independent WNT signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-425381","pathwayName":"Bicarbonate transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-194068","pathwayName":"Bile acid and bile salt metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2173782","pathwayName":"Binding and Uptake of Ligands by Scavenger Receptors","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-211859","pathwayName":"Biological oxidations","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026395","pathwayName":"Biosynthesis of DHA-derived sulfido conjugates","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018683","pathwayName":"Biosynthesis of DPA-derived SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026403","pathwayName":"Biosynthesis of DPAn-3-derived 13-series resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9026286","pathwayName":"Biosynthesis of DPAn-3-derived protectins and resolvins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9027307","pathwayName":"Biosynthesis of maresin-like SPMs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9018678","pathwayName":"Biosynthesis of specialized proresolving mediators (SPMs)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9033658","pathwayName":"Blood group systems biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5621481","pathwayName":"C-type lectin receptors (CLRs)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-442742","pathwayName":"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-211999","pathwayName":"CYP2E1 reactions","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-111996","pathwayName":"Ca-dependent events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-72737","pathwayName":"Cap-dependent Translation Initiation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5576891","pathwayName":"Cardiac conduction","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-5620920","pathwayName":"Cargo trafficking to the periciliary membrane","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-5357769","pathwayName":"Caspase activation via extrinsic apoptotic signalling pathway","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-69620","pathwayName":"Cell Cycle Checkpoints","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69278","pathwayName":"Cell Cycle, Mitotic","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-204998","pathwayName":"Cell death signalling via NRAGE, NRIF and NADE","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-446728","pathwayName":"Cell junction organization","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9664424","pathwayName":"Cell recruitment (pro-inflammatory response)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-421270","pathwayName":"Cell-cell junction organization","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-2559583","pathwayName":"Cellular Senescence","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9711123","pathwayName":"Cellular response to chemical stress","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-3371556","pathwayName":"Cellular response to heat stress","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-9711097","pathwayName":"Cellular response to starvation","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-2262752","pathwayName":"Cellular responses to stress","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-380287","pathwayName":"Centrosome maturation","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-390466","pathwayName":"Chaperonin-mediated protein folding","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-6807047","pathwayName":"Cholesterol biosynthesis via desmosterol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6807062","pathwayName":"Cholesterol biosynthesis via lathosterol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2022870","pathwayName":"Chondroitin sulfate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1793185","pathwayName":"Chondroitin sulfate/dermatan sulfate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-73886","pathwayName":"Chromosome Maintenance","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-983169","pathwayName":"Class I MHC mediated antigen processing & presentation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-196741","pathwayName":"Cobalamin (Cbl, vitamin B12) transport and metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1474290","pathwayName":"Collagen formation","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-166658","pathwayName":"Complement cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-177135","pathwayName":"Conjugation of benzoate with glycine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-159424","pathwayName":"Conjugation of carboxylic acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-177162","pathwayName":"Conjugation of phenylacetate with glutamine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-177128","pathwayName":"Conjugation of salicylate with glycine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-389958","pathwayName":"Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-166786","pathwayName":"Creation of C4 and C2 activators","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-111461","pathwayName":"Cytochrome c-mediated apoptotic response","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-1280215","pathwayName":"Cytokine Signaling in Immune system","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-73893","pathwayName":"DNA Damage Bypass","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-73942","pathwayName":"DNA Damage Reversal","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5693606","pathwayName":"DNA Double Strand Break Response","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5693532","pathwayName":"DNA Double-Strand Break Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-69002","pathwayName":"DNA Replication Pre-Initiation","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-9669914","pathwayName":"Dasatinib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-429914","pathwayName":"Deadenylation-dependent mRNA decay","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-73887","pathwayName":"Death Receptor Signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5682294","pathwayName":"Defective ABCA12 causes ARCI4B","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5688399","pathwayName":"Defective ABCA3 causes SMDP3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5683678","pathwayName":"Defective ABCA3 causes SMDP3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5678520","pathwayName":"Defective ABCB11 causes PFIC2 and BRIC2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5678771","pathwayName":"Defective ABCB4 causes PFIC3, ICP3 and GBD1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5683371","pathwayName":"Defective ABCB6 causes MCOPCB7","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5679001","pathwayName":"Defective ABCC2 causes DJS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5690338","pathwayName":"Defective ABCC6 causes PXE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5684045","pathwayName":"Defective ABCD1 causes ALD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579031","pathwayName":"Defective ACTH causes obesity and POMCD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9734735","pathwayName":"Defective ADA disrupts (deoxy)adenosine deamination","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4549380","pathwayName":"Defective ALG1 causes CDG-1k","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4551295","pathwayName":"Defective ALG11 causes CDG-1p","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4720489","pathwayName":"Defective ALG12 causes CDG-1g","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4549349","pathwayName":"Defective ALG2 causes CDG-1i","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4720475","pathwayName":"Defective ALG3 causes CDG-1d","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4724289","pathwayName":"Defective ALG6 causes CDG-1c","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4724325","pathwayName":"Defective ALG8 causes CDG-1h","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4720454","pathwayName":"Defective ALG9 causes CDG-1l","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619099","pathwayName":"Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9036092","pathwayName":"Defective AVP does not bind AVPR2 and causes neurohypophyseal diabetes insipidus (NDI)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4420332","pathwayName":"Defective B3GALT6 causes EDSP2 and SEMDJL1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083635","pathwayName":"Defective B3GALTL causes PpS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656244","pathwayName":"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4793953","pathwayName":"Defective B4GALT1 causes CDG-2d","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3560783","pathwayName":"Defective B4GALT7 causes EDS, progeroid type","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3371598","pathwayName":"Defective BTD causes biotidinase deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9605310","pathwayName":"Defective Base Excision Repair Associated with MUTYH","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9616333","pathwayName":"Defective Base Excision Repair Associated with NTHL1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9656249","pathwayName":"Defective Base Excision Repair Associated with OGG1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359457","pathwayName":"Defective CBLIF causes IFD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3595174","pathwayName":"Defective CHST14 causes EDS, musculocontractural type","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3595172","pathwayName":"Defective CHST3 causes SEDCJD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656225","pathwayName":"Defective CHST6 causes MCDC1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3595177","pathwayName":"Defective CHSY1 causes TPBS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579017","pathwayName":"Defective CYP11B1 causes AH4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579009","pathwayName":"Defective CYP11B2 causes CMO-1 deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579028","pathwayName":"Defective CYP17A1 causes AH5","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579030","pathwayName":"Defective CYP19A1 causes AEXS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579000","pathwayName":"Defective CYP1B1 causes Glaucoma","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579021","pathwayName":"Defective CYP21A2 causes AH3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579010","pathwayName":"Defective CYP24A1 causes HCAI","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579015","pathwayName":"Defective CYP26B1 causes RHFCA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579004","pathwayName":"Defective CYP26C1 causes FFDD4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5578996","pathwayName":"Defective CYP27A1 causes CTX","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579014","pathwayName":"Defective CYP27B1 causes VDDR1A","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579027","pathwayName":"Defective CYP27B1 causes VDDR1B","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579011","pathwayName":"Defective CYP2U1 causes SPG56","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579005","pathwayName":"Defective CYP4F22 causes ARCI5","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579013","pathwayName":"Defective CYP7B1 causes SPG5A and CBAS3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9699150","pathwayName":"Defective DNA double strand break response due to BARD1 loss of function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9663199","pathwayName":"Defective DNA double strand break response due to BRCA1 loss of function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4755583","pathwayName":"Defective DOLK causes DOLK-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4549356","pathwayName":"Defective DPAGT1 causes CDG-1j, CMSTA2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9672397","pathwayName":"Defective F8 secretion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674519","pathwayName":"Defective F8 sulfation at Y1699","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673218","pathwayName":"Defective F9 secretion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5609976","pathwayName":"Defective GALK1 causes GALCT2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083636","pathwayName":"Defective GALNT12 causes CRCS1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083625","pathwayName":"Defective GALNT3 causes HFTC","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5609978","pathwayName":"Defective GALT can cause GALCT","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619073","pathwayName":"Defective GCK causes maturity-onset diabetes of the young 2 (MODY2)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4085023","pathwayName":"Defective GFPT1 causes CMSTA1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579022","pathwayName":"Defective GGT1 causes GLUTH","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9035968","pathwayName":"Defective GGT1 in aflatoxin detoxification causes GLUTH","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4085011","pathwayName":"Defective GNE causes sialuria, NK and IBM2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656234","pathwayName":"Defective HEXA causes GM2G1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656248","pathwayName":"Defective HEXB causes GM2G2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619056","pathwayName":"Defective HK1 causes hexokinase deficiency (HK deficiency)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9670621","pathwayName":"Defective Inhibition of DNA Recombination at Telomere","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9670615","pathwayName":"Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9670613","pathwayName":"Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9734009","pathwayName":"Defective Intrinsic Pathway for Apoptosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083630","pathwayName":"Defective LFNG causes SCDO3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4793952","pathwayName":"Defective MGAT2 causes CDG-2a","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359471","pathwayName":"Defective MMAB causes MMA, cblB type","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359474","pathwayName":"Defective MMACHC causes MAHCC","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4687000","pathwayName":"Defective MPDU1 causes CDG-1f","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4043916","pathwayName":"Defective MPI causes MPI-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9608287","pathwayName":"Defective MUTYH substrate binding","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5545483","pathwayName":"Defective Mismatch Repair Associated With MLH1","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5632928","pathwayName":"Defective Mismatch Repair Associated With MSH2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5632927","pathwayName":"Defective Mismatch Repair Associated With MSH3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5632968","pathwayName":"Defective Mismatch Repair Associated With MSH6","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5632987","pathwayName":"Defective Mismatch Repair Associated With PMS2","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9630222","pathwayName":"Defective NTHL1 substrate binding","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9657050","pathwayName":"Defective OGG1 Localization","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9656255","pathwayName":"Defective OGG1 Substrate Binding","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5578998","pathwayName":"Defective OPLAH causes OPLAHD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3560796","pathwayName":"Defective PAPSS2 causes SEMD-PA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4043911","pathwayName":"Defective PMM2 causes PMM2-CDG","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5083628","pathwayName":"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4570571","pathwayName":"Defective RFT1 causes CDG-1n","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619042","pathwayName":"Defective RHAG causes regulator type Rh-null hemolytic anemia (RHN)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5687868","pathwayName":"Defective SFTPA2 causes IPF","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619048","pathwayName":"Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619104","pathwayName":"Defective SLC12A1 causes Bartter syndrome 1 (BS1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619087","pathwayName":"Defective SLC12A3 causes Gitelman syndrome (GS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619039","pathwayName":"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619035","pathwayName":"Defective SLC17A5 causes Salla disease (SD) and ISSD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619076","pathwayName":"Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619067","pathwayName":"Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619062","pathwayName":"Defective SLC1A3 causes episodic ataxia 6 (EA6)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619111","pathwayName":"Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619071","pathwayName":"Defective SLC22A12 causes renal hypouricemia 1 (RHUC1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619066","pathwayName":"Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619053","pathwayName":"Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619077","pathwayName":"Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619055","pathwayName":"Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619036","pathwayName":"Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619085","pathwayName":"Defective SLC26A3 causes congenital secretory chloride diarrhea 1 (DIAR1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619046","pathwayName":"Defective SLC26A4 causes Pendred syndrome (PDS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619108","pathwayName":"Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619063","pathwayName":"Defective SLC29A3 causes histiocytosis-lymphadenopathy plus syndrome (HLAS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619043","pathwayName":"Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619068","pathwayName":"Defective SLC2A10 causes arterial tortuosity syndrome (ATS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619098","pathwayName":"Defective SLC2A2 causes Fanconi-Bickel syndrome (FBS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619047","pathwayName":"Defective SLC2A9 causes hypouricemia renal 2 (RHUC2)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619061","pathwayName":"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619040","pathwayName":"Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5687583","pathwayName":"Defective SLC34A2 causes PALM","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619045","pathwayName":"Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619097","pathwayName":"Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619037","pathwayName":"Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5663020","pathwayName":"Defective SLC35A1 causes congenital disorder of glycosylation 2F (CDG2F)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619072","pathwayName":"Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619083","pathwayName":"Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619078","pathwayName":"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579020","pathwayName":"Defective SLC35D1 causes SCHBCKD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619041","pathwayName":"Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619088","pathwayName":"Defective SLC39A4 causes acrodermatitis enteropathica, zinc-deficiency type (AEZ)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619050","pathwayName":"Defective SLC4A1 causes hereditary spherocytosis type 4 (HSP4),  distal renal tubular acidosis (dRTA) and dRTA with hemolytic anemia (dRTA-HA)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619054","pathwayName":"Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5656364","pathwayName":"Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5658208","pathwayName":"Defective SLC5A2 causes renal glucosuria (GLYS1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619096","pathwayName":"Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5658471","pathwayName":"Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619114","pathwayName":"Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5659729","pathwayName":"Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619079","pathwayName":"Defective SLC6A18 may confer susceptibility to iminoglycinuria and/or hyperglycinuria","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5659735","pathwayName":"Defective SLC6A19 causes Hartnup disorder (HND)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619044","pathwayName":"Defective SLC6A19 causes Hartnup disorder (HND)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619109","pathwayName":"Defective SLC6A2 causes orthostatic intolerance (OI)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619081","pathwayName":"Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660724","pathwayName":"Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619089","pathwayName":"Defective SLC6A5 causes hyperekplexia 3 (HKPX3)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619092","pathwayName":"Defective SLC9A6 causes  X-linked, syndromic mental retardation,, Christianson type (MRXSCH)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619052","pathwayName":"Defective SLC9A9 causes autism 16 (AUTS16)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619110","pathwayName":"Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619058","pathwayName":"Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619095","pathwayName":"Defective SLCO2A1 causes primary, autosomal recessive hypertrophic osteoarthropathy 2 (PHOAR2)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4755579","pathwayName":"Defective SRD5A3 causes SRD5A3-CDG, KHRZ","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656243","pathwayName":"Defective ST3GAL3 causes MCT12 and EIEE15","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579032","pathwayName":"Defective TBXAS1 causes GHDD","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3359454","pathwayName":"Defective TCN2 causes TCN2 deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5578995","pathwayName":"Defective TPMT causes TPMT deficiency","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579002","pathwayName":"Defective UGT1A1 causes hyperbilirubinemia","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5579016","pathwayName":"Defective UGT1A4 causes hyperbilirubinemia","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9668250","pathwayName":"Defective factor IX causes hemophilia B","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9662001","pathwayName":"Defective factor VIII causes hemophilia A","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673240","pathwayName":"Defective gamma-carboxylation of F9","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9701190","pathwayName":"Defective homologous recombination repair (HRR) due to BRCA2 loss of function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9701193","pathwayName":"Defective homologous recombination repair (HRR) due to PALB2 loss of function","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5688031","pathwayName":"Defective pro-SFTPB causes SMDP1 and RDS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5688354","pathwayName":"Defective pro-SFTPC causes SMDP2 and RDS","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9661070","pathwayName":"Defective translocation of RB1 mutants to the nucleus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3323169","pathwayName":"Defects in biotin (Btn) metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3296469","pathwayName":"Defects in cobalamin (B12) metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3296482","pathwayName":"Defects in vitamin and cofactor metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9651496","pathwayName":"Defects of contact activation system (CAS) and kallikrein/kinin system (KKS)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9823587","pathwayName":"Defects of platelet adhesion to exposed collagen","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5467343","pathwayName":"Deletions in the AMER1 gene destabilize the destruction complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5467345","pathwayName":"Deletions in the AXIN1 gene destabilize the destruction complex","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-73927","pathwayName":"Depurination","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-73928","pathwayName":"Depyrimidination","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-2022923","pathwayName":"Dermatan sulfate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5688426","pathwayName":"Deubiquitination","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9734767","pathwayName":"Developmental Cell Lineages","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9725554","pathwayName":"Differentiation of keratinocytes in interfollicular epidermis in mammalian skin","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-3781860","pathwayName":"Diseases associated with N-glycosylation of proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3906995","pathwayName":"Diseases associated with O-glycosylation of proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3560782","pathwayName":"Diseases associated with glycosaminoglycan metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5609975","pathwayName":"Diseases associated with glycosylation precursor biosynthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5687613","pathwayName":"Diseases associated with surfactant metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5602358","pathwayName":"Diseases associated with the TLR signaling cascade","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2474795","pathwayName":"Diseases associated with visual transduction","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9605308","pathwayName":"Diseases of Base Excision Repair","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9630747","pathwayName":"Diseases of Cellular Senescence","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675136","pathwayName":"Diseases of DNA Double-Strand Break Repair","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675135","pathwayName":"Diseases of DNA repair","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5260271","pathwayName":"Diseases of Immune System","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5423599","pathwayName":"Diseases of Mismatch Repair (MMR)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9673013","pathwayName":"Diseases of Telomere Maintenance","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5663084","pathwayName":"Diseases of carbohydrate metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675132","pathwayName":"Diseases of cellular response to stress","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3781865","pathwayName":"Diseases of glycosylation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9671793","pathwayName":"Diseases of hemostasis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5668914","pathwayName":"Diseases of metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9759774","pathwayName":"Diseases of mitochondrial beta oxidation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675126","pathwayName":"Diseases of mitotic cell cycle","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9735804","pathwayName":"Diseases of nucleotide metabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9645723","pathwayName":"Diseases of programmed cell death","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9759785","pathwayName":"Diseases of propionyl-CoA catabolism","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5663202","pathwayName":"Diseases of signal transduction by growth factor receptors and second messengers","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675143","pathwayName":"Diseases of the neuronal system","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9675151","pathwayName":"Disorders of Developmental Biology","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9697154","pathwayName":"Disorders of Nervous System Development","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619115","pathwayName":"Disorders of transmembrane transporters","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1168372","pathwayName":"Downstream signaling events of B Cell Receptor (BCR)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5654696","pathwayName":"Downstream signaling of activated FGFR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654708","pathwayName":"Downstream signaling of activated FGFR3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654716","pathwayName":"Downstream signaling of activated FGFR4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9665230","pathwayName":"Drug resistance in ERBB2 KD mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9700649","pathwayName":"Drug resistance of ALK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702506","pathwayName":"Drug resistance of FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9669937","pathwayName":"Drug resistance of KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674415","pathwayName":"Drug resistance of PDGFR mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9750126","pathwayName":"Drug-induced formation of DNA interstrand crosslinks","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-113510","pathwayName":"E2F mediated regulation of DNA replication","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9772572","pathwayName":"Early SARS-CoV-2 Infection Events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-211979","pathwayName":"Eicosanoids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-212165","pathwayName":"Epigenetic regulation of gene expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9637679","pathwayName":"Escape of Mtb from the phagocyte","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5662853","pathwayName":"Essential pentosuria","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-72613","pathwayName":"Eukaryotic Translation Initiation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9630791","pathwayName":"Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9630794","pathwayName":"Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9646303","pathwayName":"Evasion of Oncogene Induced Senescence Due to p14ARF Defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9630750","pathwayName":"Evasion of Oncogene Induced Senescence Due to p16INK4A Defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9632697","pathwayName":"Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9632700","pathwayName":"Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9646304","pathwayName":"Evasion of Oxidative Stress Induced Senescence Due to p14ARF Defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9632693","pathwayName":"Evasion of Oxidative Stress Induced Senescence Due to p16INK4A Defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168274","pathwayName":"Export of Viral Ribonucleoproteins from Nucleus","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9036866","pathwayName":"Expression and Processing of Neurotrophins","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-180786","pathwayName":"Extension of Telomeres","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2644605","pathwayName":"FBXW7 Mutants and NOTCH1 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190242","pathwayName":"FGFR1 ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1839124","pathwayName":"FGFR1 mutant receptor activation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190241","pathwayName":"FGFR2 ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1839126","pathwayName":"FGFR2 mutant receptor activation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190239","pathwayName":"FGFR3 ligand binding and activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2033514","pathwayName":"FGFR3 mutant receptor activation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9682385","pathwayName":"FLT3 signaling in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9614085","pathwayName":"FOXO-mediated transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8978868","pathwayName":"Fatty acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-211935","pathwayName":"Fatty acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2029480","pathwayName":"Fcgamma receptor (FCGR) dependent phagocytosis","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1187000","pathwayName":"Fertilization","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-140877","pathwayName":"Formation of Fibrin Clot (Clotting Cascade)","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-2408499","pathwayName":"Formation of selenosugars for excretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-400451","pathwayName":"Free fatty acids regulate insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5652084","pathwayName":"Fructose metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-168270","pathwayName":"Fusion and Uncoating of the Influenza Virion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1296059","pathwayName":"G protein gated Potassium channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-397795","pathwayName":"G-protein beta:gamma signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-112040","pathwayName":"G-protein mediated events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-69236","pathwayName":"G1 Phase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69615","pathwayName":"G1/S DNA Damage Checkpoints","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69206","pathwayName":"G1/S Transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69275","pathwayName":"G2/M Transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-388396","pathwayName":"GPCR downstream signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-500792","pathwayName":"GPCR ligand binding","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-159854","pathwayName":"Gamma-carboxylation, transport, and amino-terminal cleavage of proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-190828","pathwayName":"Gap junction trafficking","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-157858","pathwayName":"Gap junction trafficking and regulation","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-9758941","pathwayName":"Gastrulation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-211000","pathwayName":"Gene Silencing by RNA","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5696399","pathwayName":"Global Genome Nucleotide Excision Repair (GG-NER)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-70326","pathwayName":"Glucose metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-399721","pathwayName":"Glutamate binding, activation of AMPA receptors and synaptic plasticity","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-6814848","pathwayName":"Glycerophospholipid catabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8982491","pathwayName":"Glycogen metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-3274531","pathwayName":"Glycogen storage disease type Ia (G6PC)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3229133","pathwayName":"Glycogen storage disease type Ib (SLC37A4)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3229121","pathwayName":"Glycogen storage diseases","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1630316","pathwayName":"Glycosaminoglycan metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660662","pathwayName":"Glycosphingolipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8856688","pathwayName":"Golgi-to-ER retrograde transport","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-9609646","pathwayName":"HCMV Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5693567","pathwayName":"HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-5658034","pathwayName":"HHAT G278V doesn't palmitoylate Hh-Np","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-162906","pathwayName":"HIV Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-162587","pathwayName":"HIV Life Cycle","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-167169","pathwayName":"HIV Transcription Elongation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1638091","pathwayName":"Heparan sulfate/heparin (HS-GAG) metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5387390","pathwayName":"Hh mutants abrogate ligand secretion","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5693538","pathwayName":"Homology Directed Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-162909","pathwayName":"Host Interactions of HIV factors","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2142850","pathwayName":"Hyaluronan biosynthesis and export","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2142845","pathwayName":"Hyaluronan metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483152","pathwayName":"Hydrolysis of LPE","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2428924","pathwayName":"IGF1R signaling cascade","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5602636","pathwayName":"IKBKB deficiency causes SCID","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5603027","pathwayName":"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1855196","pathwayName":"IP3 and IP4 transport between cytosol and nucleus","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855229","pathwayName":"IP6 and IP7 transport between cytosol and nucleus","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855215","pathwayName":"IPs transport between ER lumen and cytosol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855156","pathwayName":"IPs transport between ER lumen and nucleus","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855184","pathwayName":"IPs transport between cytosol and ER lumen","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855192","pathwayName":"IPs transport between nucleus and ER lumen","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855170","pathwayName":"IPs transport between nucleus and cytosol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9669917","pathwayName":"Imatinib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674396","pathwayName":"Imatinib-resistant PDGFR mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9763198","pathwayName":"Impaired BRCA2 binding to SEM1 (DSS1)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-400508","pathwayName":"Incretin synthesis, secretion, and inactivation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9635486","pathwayName":"Infection with Mycobacterium tuberculosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5663205","pathwayName":"Infectious disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-622312","pathwayName":"Inflammasomes","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168273","pathwayName":"Influenza Viral RNA Transcription and Replication","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168305","pathwayName":"Inhibition of Interferon Synthesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168249","pathwayName":"Innate Immune System","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1483249","pathwayName":"Inositol phosphate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-429593","pathwayName":"Inositol transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-177243","pathwayName":"Interactions of Rev with host cellular proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-176033","pathwayName":"Interactions of Vpr with host cellular proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-880009","pathwayName":"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-913531","pathwayName":"Interferon Signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-446652","pathwayName":"Interleukin-1 family signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-447115","pathwayName":"Interleukin-12 family signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-6783589","pathwayName":"Interleukin-6 family signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-8963676","pathwayName":"Intestinal absorption","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-6811442","pathwayName":"Intra-Golgi and retrograde Golgi-to-ER traffic","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-434313","pathwayName":"Intracellular metabolism of fatty acids regulates insulin secretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9006925","pathwayName":"Intracellular signaling by second messengers","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-109606","pathwayName":"Intrinsic Pathway for Apoptosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-1296065","pathwayName":"Inwardly rectifying K+ channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-451306","pathwayName":"Ionotropic activity of kainate receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1638074","pathwayName":"Keratan sulfate/keratin metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-74182","pathwayName":"Ketone body metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9830369","pathwayName":"Kidney development","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9664420","pathwayName":"Killing mechanisms","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-162599","pathwayName":"Late Phase of HIV Life Cycle","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9772573","pathwayName":"Late SARS-CoV-2 Infection Events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1222499","pathwayName":"Latent infection - Other responses of Mtb to phagocytosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9658195","pathwayName":"Leishmania infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9664433","pathwayName":"Leishmania parasite growth and survival","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9664417","pathwayName":"Leishmania phagocytosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9037629","pathwayName":"Lewis blood group biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8876384","pathwayName":"Listeria monocytogenes entry into host cells","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3304349","pathwayName":"Loss of Function of SMAD2/3 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3304347","pathwayName":"Loss of Function of SMAD4 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3656534","pathwayName":"Loss of Function of TGFBR1 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3642278","pathwayName":"Loss of Function of TGFBR2 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9723907","pathwayName":"Loss of Function of TP53 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9022534","pathwayName":"Loss of MECP2 binding ability to 5hmC-DNA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9005891","pathwayName":"Loss of function of MECP2 in Rett syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9723905","pathwayName":"Loss of function of TP53 in cancer due to loss of tetramerization ability","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-68886","pathwayName":"M Phase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5683057","pathwayName":"MAPK family signaling cascades","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5684996","pathwayName":"MAPK1/MAPK3 signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-8875878","pathwayName":"MET promotes cell motility","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9856651","pathwayName":"MITF-M-dependent gene expression","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9730414","pathwayName":"MITF-M-regulated melanocyte development","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-2206302","pathwayName":"MPS I - Hurler syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206307","pathwayName":"MPS IIIA - Sanfilippo syndrome A","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206282","pathwayName":"MPS IIIB - Sanfilippo syndrome B","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206291","pathwayName":"MPS IIIC - Sanfilippo syndrome C","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206305","pathwayName":"MPS IIID - Sanfilippo syndrome D","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206290","pathwayName":"MPS IV - Morquio syndrome A","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206308","pathwayName":"MPS IV - Morquio syndrome B","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206280","pathwayName":"MPS IX - Natowicz syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2206292","pathwayName":"MPS VII - Sly syndrome","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9669924","pathwayName":"Masitinib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9816359","pathwayName":"Maternal to zygotic transition (MZT)","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9683612","pathwayName":"Maturation of protein M","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694594","pathwayName":"Maturation of protein M","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-199991","pathwayName":"Membrane Trafficking","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-5579029","pathwayName":"Metabolic disorders of biological oxidation enzymes","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-209776","pathwayName":"Metabolism of amine-derived hormones","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-71291","pathwayName":"Metabolism of amino acids and derivatives","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-71387","pathwayName":"Metabolism of carbohydrates","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8978934","pathwayName":"Metabolism of cofactors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6806667","pathwayName":"Metabolism of fat-soluble vitamins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-556833","pathwayName":"Metabolism of lipids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-202131","pathwayName":"Metabolism of nitric oxide: NOS3 activation and regulation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-194441","pathwayName":"Metabolism of non-coding RNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-15869","pathwayName":"Metabolism of nucleotides","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-351202","pathwayName":"Metabolism of polyamines","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-189445","pathwayName":"Metabolism of porphyrins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8957322","pathwayName":"Metabolism of steroids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196854","pathwayName":"Metabolism of vitamins and cofactors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-196849","pathwayName":"Metabolism of water-soluble vitamins and cofactors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2408552","pathwayName":"Methylation of MeSeH for excretion","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9715370","pathwayName":"Miro GTPase Cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-211958","pathwayName":"Miscellaneous substrates","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5358508","pathwayName":"Mismatch Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-166187","pathwayName":"Mitochondrial Uncoupling","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1592230","pathwayName":"Mitochondrial biogenesis","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-5368287","pathwayName":"Mitochondrial translation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5205647","pathwayName":"Mitophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-68882","pathwayName":"Mitotic Anaphase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-453279","pathwayName":"Mitotic G1 phase and G1/S transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-453274","pathwayName":"Mitotic G2-G2/M phases","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2555396","pathwayName":"Mitotic Metaphase and Anaphase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-68881","pathwayName":"Mitotic Metaphase/Anaphase Transition","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69618","pathwayName":"Mitotic Spindle Checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-68884","pathwayName":"Mitotic Telophase/Cytokinesis","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-2206281","pathwayName":"Mucopolysaccharidoses","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-427601","pathwayName":"Multifunctional anion exchangers","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-975576","pathwayName":"N-glycan antennae elongation in the medial/trans-Golgi","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-964739","pathwayName":"N-glycan trimming and elongation in the cis-Golgi","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9636003","pathwayName":"NEIL3-mediated resolution of ICLs","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9024446","pathwayName":"NR1H2 and NR1H3-mediated signaling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-442660","pathwayName":"Na+/Cl- dependent neurotransmitter transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-164938","pathwayName":"Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5250941","pathwayName":"Negative epigenetic regulation of rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9675108","pathwayName":"Nervous system development","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8863678","pathwayName":"Neurodegenerative Diseases","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168799","pathwayName":"Neurotoxicity of clostridium toxins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-112313","pathwayName":"Neurotransmitter uptake and metabolism In glial cells","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-6798695","pathwayName":"Neutrophil degranulation","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9669926","pathwayName":"Nilotinib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-927802","pathwayName":"Nonsense-Mediated Decay (NMD)","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-2995410","pathwayName":"Nuclear Envelope (NE) Reassembly","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-198725","pathwayName":"Nuclear Events (kinase and transcription factor activation)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-774815","pathwayName":"Nucleosome assembly","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5696398","pathwayName":"Nucleotide Excision Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-8956320","pathwayName":"Nucleotide biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9735786","pathwayName":"Nucleotide catabolism defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8956321","pathwayName":"Nucleotide salvage","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9734207","pathwayName":"Nucleotide salvage defects","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168643","pathwayName":"Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-418038","pathwayName":"Nucleotide-like (purinergic) receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5173214","pathwayName":"O-glycosylation of TSR domain-containing proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1480926","pathwayName":"O2/CO2 exchange in erythrocytes","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9673163","pathwayName":"Oleoyl-phe metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-6802957","pathwayName":"Oncogenic MAPK signaling","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-561048","pathwayName":"Organic anion transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-549127","pathwayName":"Organic cation transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-549132","pathwayName":"Organic cation/anion/zwitterion transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-1483255","pathwayName":"PI Metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2219528","pathwayName":"PI3K/AKT Signaling in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1660510","pathwayName":"PIPs transport between Golgi and plasma membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660502","pathwayName":"PIPs transport between early and late endosome membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660537","pathwayName":"PIPs transport between early endosome and Golgi membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660508","pathwayName":"PIPs transport between late endosome and Golgi membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1660524","pathwayName":"PIPs transport between plasma and early endosome membranes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-5674404","pathwayName":"PTEN Loss of Function in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6807070","pathwayName":"PTEN Regulation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9664407","pathwayName":"Parasite infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9824443","pathwayName":"Parasitic Infection Pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6791465","pathwayName":"Pentose phosphate pathway disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2980736","pathwayName":"Peptide hormone metabolism","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9005895","pathwayName":"Pervasive developmental disorders","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9637698","pathwayName":"Phagocyte cell death caused by cytosolic Mtb","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-156580","pathwayName":"Phase II - Conjugation of compounds","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8963691","pathwayName":"Phenylalanine and tyrosine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483257","pathwayName":"Phospholipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8963898","pathwayName":"Plasma lipoprotein assembly","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-174824","pathwayName":"Plasma lipoprotein assembly, remodeling, and clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8964043","pathwayName":"Plasma lipoprotein clearance","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8963899","pathwayName":"Plasma lipoprotein remodeling","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-76002","pathwayName":"Platelet activation, signaling and aggregation","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-418360","pathwayName":"Platelet calcium homeostasis","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-5250913","pathwayName":"Positive epigenetic regulation of rRNA expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-438064","pathwayName":"Post NMDA receptor activation events","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-597592","pathwayName":"Post-translational protein modification","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-622327","pathwayName":"Postsynaptic nicotinic acetylcholine receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1296071","pathwayName":"Potassium Channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1912422","pathwayName":"Pre-NOTCH Expression and Processing","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1912399","pathwayName":"Pre-NOTCH Processing in the Endoplasmic Reticulum","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-622323","pathwayName":"Presynaptic nicotinic acetylcholine receptors","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-3215018","pathwayName":"Processing and activation of SUMO","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-75067","pathwayName":"Processing of Capped Intronless Pre-mRNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-964827","pathwayName":"Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-169893","pathwayName":"Prolonged ERK activation events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-391251","pathwayName":"Protein folding","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8876725","pathwayName":"Protein methylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-5676934","pathwayName":"Protein repair","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-8852135","pathwayName":"Protein ubiquitination","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-6794362","pathwayName":"Protein-protein interactions at synapses","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-428559","pathwayName":"Proton-coupled neutral amino acid transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-427975","pathwayName":"Proton/oligopeptide cotransporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9649913","pathwayName":"RAS GTPase cycle mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-195258","pathwayName":"RHO GTPase Effectors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9012999","pathwayName":"RHO GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9706574","pathwayName":"RHOBTB GTPase Cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-73854","pathwayName":"RNA Polymerase I Promoter Clearance","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73864","pathwayName":"RNA Polymerase I Transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-73857","pathwayName":"RNA Polymerase II Transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-74158","pathwayName":"RNA Polymerase III Transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-76046","pathwayName":"RNA Polymerase III Transcription Initiation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5659996","pathwayName":"RPIA deficiency: failed conversion of R5P to RU5P","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6791461","pathwayName":"RPIA deficiency: failed conversion of RU5P to R5P","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9007101","pathwayName":"Rab regulation of trafficking","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-975574","pathwayName":"Reactions specific to the hybrid N-glycan synthesis pathway","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-418359","pathwayName":"Reduction of cytosolic Ca++ levels","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-9669929","pathwayName":"Regorafenib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674403","pathwayName":"Regorafenib-resistant PDGFR mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5218859","pathwayName":"Regulated Necrosis","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-9759475","pathwayName":"Regulation of CDH11 Expression and Function","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9764260","pathwayName":"Regulation of Expression and Function of Type II Classical Cadherins","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9759476","pathwayName":"Regulation of Homotypic Cell-Cell Adhesion","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-9768759","pathwayName":"Regulation of NPAS4 gene expression","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8948747","pathwayName":"Regulation of PTEN localization","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5633007","pathwayName":"Regulation of TP53 Activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-6806003","pathwayName":"Regulation of TP53 Expression and Degradation","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-186712","pathwayName":"Regulation of beta-cell development","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-210747","pathwayName":"Regulation of gene expression in early pancreatic precursor cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-210746","pathwayName":"Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-450531","pathwayName":"Regulation of mRNA stability by proteins that bind AU-rich elements","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-453276","pathwayName":"Regulation of mitotic cell cycle","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-5693537","pathwayName":"Resolution of D-Loop Structures","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9820952","pathwayName":"Respiratory Syncytial Virus Infection Pathway","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-163200","pathwayName":"Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9820965","pathwayName":"Respiratory syncytial virus (RSV) genome replication, transcription and translation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9637690","pathwayName":"Response of Mtb to phagocytosis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660526","pathwayName":"Response to metal ions","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-6809583","pathwayName":"Retinoid metabolism disease events","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-888593","pathwayName":"Reuptake of GABA","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-162589","pathwayName":"Reverse Transcription of HIV RNA","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9729902","pathwayName":"Reversible DNA damage induced by alkylating chemotherapeutic drugs","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-9037628","pathwayName":"Rhesus blood group biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-444411","pathwayName":"Rhesus glycoproteins mediate ammonium transport.","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-69242","pathwayName":"S Phase","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-9679506","pathwayName":"SARS-CoV Infections","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9679514","pathwayName":"SARS-CoV-1 Genome Replication and Transcription","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9678108","pathwayName":"SARS-CoV-1 Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694682","pathwayName":"SARS-CoV-2 Genome Replication and Transcription","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694516","pathwayName":"SARS-CoV-2 Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9705683","pathwayName":"SARS-CoV-2-host interactions","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619102","pathwayName":"SLC transporter disorders","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-425407","pathwayName":"SLC-mediated transmembrane transport","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-3315487","pathwayName":"SMAD2/3 MH2 Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3311021","pathwayName":"SMAD4 MH2 Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-3108232","pathwayName":"SUMO E3 ligases SUMOylate target proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-3065679","pathwayName":"SUMO is proteolytically processed","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2990846","pathwayName":"SUMOylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9663891","pathwayName":"Selective autophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-400685","pathwayName":"Sema4D in semaphorin signaling","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-373755","pathwayName":"Semaphorin interactions","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-9729555","pathwayName":"Sensory perception of sour taste","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9717189","pathwayName":"Sensory perception of taste","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-9659379","pathwayName":"Sensory processing of sound","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-3282872","pathwayName":"Severe congenital neutropenia type 4 (G6PC3)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-392518","pathwayName":"Signal amplification","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-9700206","pathwayName":"Signaling by ALK in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4839748","pathwayName":"Signaling by AMER1 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4839744","pathwayName":"Signaling by APC mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4839735","pathwayName":"Signaling by AXIN mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-4839743","pathwayName":"Signaling by CTNNB1 phospho-site mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1643713","pathwayName":"Signaling by EGFR in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5637812","pathwayName":"Signaling by EGFRvIII in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1227990","pathwayName":"Signaling by ERBB2 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-190236","pathwayName":"Signaling by FGFR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1226099","pathwayName":"Signaling by FGFR in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5654736","pathwayName":"Signaling by FGFR1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654738","pathwayName":"Signaling by FGFR2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654741","pathwayName":"Signaling by FGFR3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5654743","pathwayName":"Signaling by FGFR4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-372790","pathwayName":"Signaling by GPCR","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5358351","pathwayName":"Signaling by Hedgehog","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-449147","pathwayName":"Signaling by Interleukins","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9669938","pathwayName":"Signaling by KIT in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5339717","pathwayName":"Signaling by LRP5 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5637815","pathwayName":"Signaling by Ligand-Responsive EGFR Variants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9652817","pathwayName":"Signaling by MAPK mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6806834","pathwayName":"Signaling by MET","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9660537","pathwayName":"Signaling by MRAS-complex mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-157118","pathwayName":"Signaling by NOTCH","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1980143","pathwayName":"Signaling by NOTCH1","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-2691230","pathwayName":"Signaling by NOTCH1 HD Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2894858","pathwayName":"Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2644602","pathwayName":"Signaling by NOTCH1 PEST Domain Mutants in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2644603","pathwayName":"Signaling by NOTCH1 in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2660825","pathwayName":"Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-1980145","pathwayName":"Signaling by NOTCH2","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9012852","pathwayName":"Signaling by NOTCH3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9013694","pathwayName":"Signaling by NOTCH4","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-187037","pathwayName":"Signaling by NTRK1 (TRKA)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9006115","pathwayName":"Signaling by NTRK2 (TRKB)","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-166520","pathwayName":"Signaling by NTRKs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9006927","pathwayName":"Signaling by Non-Receptor Tyrosine Kinases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9006931","pathwayName":"Signaling by Nuclear Receptors","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5638302","pathwayName":"Signaling by Overexpressed Wild-Type EGFR in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9671555","pathwayName":"Signaling by PDGFR in disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8848021","pathwayName":"Signaling by PTK6","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-6802949","pathwayName":"Signaling by RAS mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9006934","pathwayName":"Signaling by Receptor Tyrosine Kinases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-194315","pathwayName":"Signaling by Rho GTPases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9716542","pathwayName":"Signaling by Rho GTPases, Miro GTPases and RHOBTB3","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-5339700","pathwayName":"Signaling by TCF7L2 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-170834","pathwayName":"Signaling by TGF-beta Receptor Complex","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3304351","pathwayName":"Signaling by TGF-beta Receptor Complex in Cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9006936","pathwayName":"Signaling by TGFB family members","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-195721","pathwayName":"Signaling by WNT","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-4791275","pathwayName":"Signaling by WNT in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9669933","pathwayName":"Signaling by kinase domain mutants of KIT","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-983705","pathwayName":"Signaling by the B Cell Receptor (BCR)","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-198765","pathwayName":"Signalling to ERK5","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-187687","pathwayName":"Signalling to ERKs","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-427652","pathwayName":"Sodium-coupled phosphate cotransporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-433137","pathwayName":"Sodium-coupled sulphate, di- and tri-carboxylate transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-425561","pathwayName":"Sodium/Calcium exchangers","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-425986","pathwayName":"Sodium/Proton exchangers","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-9669936","pathwayName":"Sorafenib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674404","pathwayName":"Sorafenib-resistant PDGFR mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-428157","pathwayName":"Sphingolipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-211994","pathwayName":"Sterols are 12-hydroxylated by CYP8B1","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9669934","pathwayName":"Sunitinib-resistant KIT mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9674401","pathwayName":"Sunitinib-resistant PDGFR mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9637687","pathwayName":"Suppression of phagosomal maturation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-174495","pathwayName":"Synthesis And Processing Of GAG, GAGPOL Polyproteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2142816","pathwayName":"Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483171","pathwayName":"Synthesis of BMP","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483076","pathwayName":"Synthesis of CL","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-446205","pathwayName":"Synthesis of GDP-mannose","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-1855231","pathwayName":"Synthesis of IPs in the ER lumen","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1855191","pathwayName":"Synthesis of IPs in the nucleus","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483148","pathwayName":"Synthesis of PG","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-1483101","pathwayName":"Synthesis of PS","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-193775","pathwayName":"Synthesis of bile acids and bile salts via 24-hydroxycholesterol","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-480985","pathwayName":"Synthesis of dolichyl-phosphate-glucose","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-446219","pathwayName":"Synthesis of substrates in N-glycan biosythesis","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-75876","pathwayName":"Synthesis of very long-chain fatty acyl-CoAs","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-202403","pathwayName":"TCR signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-5602410","pathwayName":"TLR3 deficiency - HSE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-6791312","pathwayName":"TP53 Regulates Transcription of Cell Cycle Genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-5633008","pathwayName":"TP53 Regulates Transcription of Cell Death Genes","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-937061","pathwayName":"TRIF (TICAM1)-mediated TLR4 signaling","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-9033500","pathwayName":"TYSND1 cleaves peroxisomal proteins","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-1296346","pathwayName":"Tandem pore domain potassium channels","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-157579","pathwayName":"Telomere Maintenance","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-977068","pathwayName":"Termination of O-glycan biosynthesis","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-2514856","pathwayName":"The phototransduction cascade","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-164952","pathwayName":"The role of Nef in HIV-1 replication and disease pathogenesis","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-181438","pathwayName":"Toll Like Receptor 2 (TLR2) Cascade","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-168898","pathwayName":"Toll-like Receptor Cascades","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-75944","pathwayName":"Transcription from mitochondrial promoters","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9634815","pathwayName":"Transcriptional Regulation by NPAS4","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-3700989","pathwayName":"Transcriptional Regulation by TP53","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-69560","pathwayName":"Transcriptional activation of p53 responsive genes","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-8878171","pathwayName":"Transcriptional regulation by RUNX1","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-8878159","pathwayName":"Transcriptional regulation by RUNX3","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-9843743","pathwayName":"Transcriptional regulation of brown and beige adipocyte differentiation","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-72766","pathwayName":"Translation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-9683701","pathwayName":"Translation of Structural Proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9694635","pathwayName":"Translation of Structural Proteins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9828721","pathwayName":"Translation of respiratory syncytial virus mRNAs","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-110313","pathwayName":"Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-112315","pathwayName":"Transmission across Chemical Synapses","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-112307","pathwayName":"Transmission across Electrical Synapses","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-72202","pathwayName":"Transport of Mature Transcript to Cytoplasm","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-159234","pathwayName":"Transport of Mature mRNAs Derived from Intronless Transcripts","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-425366","pathwayName":"Transport of bile salts and organic acids, metal ions and amine compounds","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-190827","pathwayName":"Transport of connexins along the secretory pathway","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-425393","pathwayName":"Transport of inorganic cations/anions and amino acids/oligopeptides","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-8979227","pathwayName":"Triglyceride metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-427589","pathwayName":"Type II Na+/Pi cotransporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5602415","pathwayName":"UNC93B1 deficiency - HSE","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-381119","pathwayName":"Unfolded Protein Response (UPR)","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-5339562","pathwayName":"Uptake and actions of bacterial toxins","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619094","pathwayName":"Variant SLC6A14 may confer susceptibility towards obesity","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5619101","pathwayName":"Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5660686","pathwayName":"Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG)","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9824446","pathwayName":"Viral Infection Pathways","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168268","pathwayName":"Virus Assembly and Release","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-2187338","pathwayName":"Visual phototransduction","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-211916","pathwayName":"Vitamins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8848584","pathwayName":"Wax and plasmalogen biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9640463","pathwayName":"Wax biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-381038","pathwayName":"XBP1(S) activates chaperone genes","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-442380","pathwayName":"Zinc influx into cells by the SLC39 gene family","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-435354","pathwayName":"Zinc transporters","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-2046104","pathwayName":"alpha-linolenic (omega3) and linoleic (omega6) acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-75072","pathwayName":"mRNA Editing","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-75064","pathwayName":"mRNA Editing: A to I Conversion","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-72172","pathwayName":"mRNA Splicing","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-77286","pathwayName":"mitochondrial fatty acid beta-oxidation of saturated fatty acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-69580","pathwayName":"p53-Dependent G1/S DNA damage checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69610","pathwayName":"p53-Independent DNA Damage Response","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-69613","pathwayName":"p53-Independent G1/S DNA damage checkpoint","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-193704","pathwayName":"p75 NTR receptor-mediated signalling","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-193697","pathwayName":"p75NTR regulates axonogenesis","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-193639","pathwayName":"p75NTR signals via NF-kB","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-9702605","pathwayName":"pexidartinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702614","pathwayName":"ponatinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702620","pathwayName":"quizartinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-72312","pathwayName":"rRNA processing","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-8868773","pathwayName":"rRNA processing in the nucleus and cytosol","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9702624","pathwayName":"sorafenib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9702632","pathwayName":"sunitinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-379724","pathwayName":"tRNA Aminoacylation","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-72306","pathwayName":"tRNA processing","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-9702636","pathwayName":"tandutinib-resistant FLT3 mutants","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-68962","pathwayName":"Activation of the pre-replicative complex","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-170670","pathwayName":"Adenylate cyclase inhibitory pathway","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-426048","pathwayName":"Arachidonate production from DAG","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-2466712","pathwayName":"Biosynthesis of A2E, implicated in retinal degradation","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-5694530","pathwayName":"Cargo concentration in the ER","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-69017","pathwayName":"CDK-mediated phosphorylation and removal of Cdc6","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-6807878","pathwayName":"COPI-mediated anterograde transport","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-204005","pathwayName":"COPII-mediated vesicle transport","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-199920","pathwayName":"CREB phosphorylation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-3560792","pathwayName":"Defective SLC26A2 causes chondrodysplasias","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-68952","pathwayName":"DNA replication initiation","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-69190","pathwayName":"DNA strand elongation","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-2173795","pathwayName":"Downregulation of SMAD2/3:SMAD4 transcriptional activity","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-114508","pathwayName":"Effects of PIP2 hydrolysis","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-199977","pathwayName":"ER to Golgi Anterograde Transport","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"R-HSA-198753","pathwayName":"ERK/MAPK targets","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-202670","pathwayName":"ERKs are inactivated","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-354194","pathwayName":"GRB2:SOS provides linkage to MAPK signaling for Integrins ","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-354192","pathwayName":"Integrin signaling","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-69186","pathwayName":"Lagging Strand Synthesis","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-69109","pathwayName":"Leading Strand Synthesis","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-450294","pathwayName":"MAP kinase activation","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-450282","pathwayName":"MAPK targets/ Nuclear events mediated by MAP kinases","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-1500620","pathwayName":"Meiosis","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-912446","pathwayName":"Meiotic recombination","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-1221632","pathwayName":"Meiotic synapsis","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-68949","pathwayName":"Orc1 removal from chromatin","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-372708","pathwayName":"p130Cas linkage to MAPK signaling for integrins","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-109703","pathwayName":"PKB-mediated events","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-69091","pathwayName":"Polymerase switching","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-69183","pathwayName":"Processive synthesis on the lagging strand","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-69166","pathwayName":"Removal of the Flap Intermediate","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-975634","pathwayName":"Retinoid metabolism and transport","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-2173796","pathwayName":"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-69052","pathwayName":"Switching of origins to a post-replicative state","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-69239","pathwayName":"Synthesis of DNA","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-2173793","pathwayName":"Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-174362","pathwayName":"Transport and synthesis of PAPS","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-176974","pathwayName":"Unwinding of DNA","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-168253","pathwayName":"Host Interactions with Influenza Factors","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-168254","pathwayName":"Influenza Infection","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-8853338","pathwayName":"Signaling by FGFR3 point mutants in cancer","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-68827","pathwayName":"CDT1 association with the CDC6:ORC:origin complex","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-9006921","pathwayName":"Integrin signaling","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-194840","pathwayName":"Rho GTPase cycle","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-71406","pathwayName":"Pyruvate metabolism and Citric Acid (TCA) cycle","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-9612973","pathwayName":"Autophagy","topLevelPathway":"Autophagy","groupedPathway":"Cell Process","topLevelOriginal":"Autophagy"}
{"pathwayId":"R-HSA-1640170","pathwayName":"Cell Cycle","topLevelPathway":"Cell Cycle","groupedPathway":"Cell Replication","topLevelOriginal":"Cell Cycle"}
{"pathwayId":"R-HSA-1500931","pathwayName":"Cell-Cell communication","topLevelPathway":"Cell-Cell communication","groupedPathway":"Signaling","topLevelOriginal":"Cell-Cell communication"}
{"pathwayId":"R-HSA-8953897","pathwayName":"Cellular responses to stimuli","topLevelPathway":"Cell responses to stimuli","groupedPathway":"Signaling","topLevelOriginal":"Cellular responses to stimuli"}
{"pathwayId":"R-HSA-4839726","pathwayName":"Chromatin organization","topLevelPathway":"Chromatin organization","groupedPathway":"Cell Replication","topLevelOriginal":"Chromatin organization"}
{"pathwayId":"R-HSA-400253","pathwayName":"Circadian Clock","topLevelPathway":"Circadian Clock","groupedPathway":"Tissue Function","topLevelOriginal":"Circadian Clock"}
{"pathwayId":"R-HSA-73894","pathwayName":"DNA Repair","topLevelPathway":"DNA Repair","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Repair"}
{"pathwayId":"R-HSA-69306","pathwayName":"DNA Replication","topLevelPathway":"DNA Replication","groupedPathway":"Cell Replication","topLevelOriginal":"DNA Replication"}
{"pathwayId":"R-HSA-1266738","pathwayName":"Developmental Biology","topLevelPathway":"Developmental Biology","groupedPathway":"Tissue Function","topLevelOriginal":"Developmental Biology"}
{"pathwayId":"R-HSA-8963743","pathwayName":"Digestion and absorption","topLevelPathway":"Digestion and absorption","groupedPathway":"Tissue Function","topLevelOriginal":"Digestion and absorption"}
{"pathwayId":"R-HSA-1643685","pathwayName":"Disease","topLevelPathway":"Disease","groupedPathway":"Disease","topLevelOriginal":"Disease"}
{"pathwayId":"R-HSA-9748784","pathwayName":"Drug ADME","topLevelPathway":"Drug ADME","groupedPathway":"Metabolism","topLevelOriginal":"Drug ADME"}
{"pathwayId":"R-HSA-1474244","pathwayName":"Extracellular matrix organization","topLevelPathway":"ECM organization","groupedPathway":"Cell Process","topLevelOriginal":"Extracellular matrix organization"}
{"pathwayId":"R-HSA-74160","pathwayName":"Gene expression (Transcription)","topLevelPathway":"Gene expression","groupedPathway":"Gene Expression","topLevelOriginal":"Gene expression (Transcription)"}
{"pathwayId":"R-HSA-109582","pathwayName":"Hemostasis","topLevelPathway":"Hemostasis","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Hemostasis"}
{"pathwayId":"R-HSA-168256","pathwayName":"Immune System","topLevelPathway":"Immune System","groupedPathway":"Immune/Hemostasis","topLevelOriginal":"Immune System"}
{"pathwayId":"R-HSA-1430728","pathwayName":"Metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism"}
{"pathwayId":"R-HSA-8953854","pathwayName":"Metabolism of RNA","topLevelPathway":"Metabolism of RNA","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of RNA"}
{"pathwayId":"R-HSA-392499","pathwayName":"Metabolism of proteins","topLevelPathway":"Metabolism of proteins","groupedPathway":"Metabolism","topLevelOriginal":"Metabolism of proteins"}
{"pathwayId":"R-HSA-397014","pathwayName":"Muscle contraction","topLevelPathway":"Muscle contraction","groupedPathway":"Tissue Function","topLevelOriginal":"Muscle contraction"}
{"pathwayId":"R-HSA-112316","pathwayName":"Neuronal System","topLevelPathway":"Neuronal System","groupedPathway":"Tissue Function","topLevelOriginal":"Neuronal System"}
{"pathwayId":"R-HSA-1852241","pathwayName":"Organelle biogenesis and maintenance","topLevelPathway":"Organelle biogenesis","groupedPathway":"Cell Process","topLevelOriginal":"Organelle biogenesis and maintenance"}
{"pathwayId":"R-HSA-5357801","pathwayName":"Programmed Cell Death","topLevelPathway":"Programmed Cell Death","groupedPathway":"Cell Process","topLevelOriginal":"Programmed Cell Death"}
{"pathwayId":"R-HSA-9609507","pathwayName":"Protein localization","topLevelPathway":"Protein localization","groupedPathway":"Cell Process","topLevelOriginal":"Protein localization"}
{"pathwayId":"R-HSA-1474165","pathwayName":"Reproduction","topLevelPathway":"Reproduction","groupedPathway":"Tissue Function","topLevelOriginal":"Reproduction"}
{"pathwayId":"R-HSA-9709957","pathwayName":"Sensory Perception","topLevelPathway":"Sensory Perception","groupedPathway":"Tissue Function","topLevelOriginal":"Sensory Perception"}
{"pathwayId":"R-HSA-162582","pathwayName":"Signal Transduction","topLevelPathway":"Signal Transduction","groupedPathway":"Signaling","topLevelOriginal":"Signal Transduction"}
{"pathwayId":"R-HSA-382551","pathwayName":"Transport of small molecules","topLevelPathway":"Transport small molecules","groupedPathway":"Cell Process","topLevelOriginal":"Transport of small molecules"}
{"pathwayId":"R-HSA-5653656","pathwayName":"Vesicle-mediated transport","topLevelPathway":"Vesicle-mediated transport","groupedPathway":"Cell Process","topLevelOriginal":"Vesicle-mediated transport"}
{"pathwayId":"ADIPOGENESIS","pathwayName":"ADIPOGENESIS","topLevelPathway":"Development"}
{"pathwayId":"ALLOGRAFT REJECTION","pathwayName":"ALLOGRAFT REJECTION","topLevelPathway":"Immune"}
{"pathwayId":"ANDROGEN RESPONSE","pathwayName":"ANDROGEN RESPONSE","topLevelPathway":"Signaling"}
{"pathwayId":"ANGIOGENESIS","pathwayName":"ANGIOGENESIS","topLevelPathway":"Development"}
{"pathwayId":"APICAL JUNCTION","pathwayName":"APICAL JUNCTION","topLevelPathway":"Cellular"}
{"pathwayId":"APICAL SURFACE","pathwayName":"APICAL SURFACE","topLevelPathway":"Cellular"}
{"pathwayId":"APOPTOSIS","pathwayName":"APOPTOSIS","topLevelPathway":"Stress"}
{"pathwayId":"BILE ACID METABOLISM","pathwayName":"BILE ACID METABOLISM","topLevelPathway":"Metabolic"}
{"pathwayId":"CHOLESTEROL HOMEOSTASIS","pathwayName":"CHOLESTEROL HOMEOSTASIS","topLevelPathway":"Metabolic"}
{"pathwayId":"COAGULATION","pathwayName":"COAGULATION","topLevelPathway":"Immune"}
{"pathwayId":"COMPLEMENT","pathwayName":"COMPLEMENT","topLevelPathway":"Immune"}
{"pathwayId":"DNA REPAIR","pathwayName":"DNA REPAIR","topLevelPathway":"DNA Damage"}
{"pathwayId":"E2F TARGETS","pathwayName":"E2F TARGETS","topLevelPathway":"Growth"}
{"pathwayId":"EPITHELIAL MESENCHYMAL TRANSITION","pathwayName":"EPITHELIAL MESENCHYMAL TRANSITION","topLevelPathway":"Development"}
{"pathwayId":"ESTROGEN RESPONSE EARLY","pathwayName":"ESTROGEN RESPONSE EARLY","topLevelPathway":"Signaling"}
{"pathwayId":"ESTROGEN RESPONSE LATE","pathwayName":"ESTROGEN RESPONSE LATE","topLevelPathway":"Signaling"}
{"pathwayId":"FATTY ACID METABOLISM","pathwayName":"FATTY ACID METABOLISM","topLevelPathway":"Metabolic"}
{"pathwayId":"G2M CHECKPOINT","pathwayName":"G2M CHECKPOINT","topLevelPathway":"Growth"}
{"pathwayId":"GLYCOLYSIS","pathwayName":"GLYCOLYSIS","topLevelPathway":"Metabolic"}
{"pathwayId":"HEDGEHOG SIGNALING","pathwayName":"HEDGEHOG SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"HEME METABOLISM","pathwayName":"HEME METABOLISM","topLevelPathway":"Metabolic"}
{"pathwayId":"HYPOXIA","pathwayName":"HYPOXIA","topLevelPathway":"Stress"}
{"pathwayId":"IL2 STAT5 SIGNALING","pathwayName":"IL2 STAT5 SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"IL6 JAK STAT3 SIGNALING","pathwayName":"IL6 JAK STAT3 SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"INFLAMMATORY RESPONSE","pathwayName":"INFLAMMATORY RESPONSE","topLevelPathway":"Immune"}
{"pathwayId":"INTERFERON ALPHA RESPONSE","pathwayName":"INTERFERON ALPHA RESPONSE","topLevelPathway":"Immune"}
{"pathwayId":"INTERFERON GAMMA RESPONSE","pathwayName":"INTERFERON GAMMA RESPONSE","topLevelPathway":"Immune"}
{"pathwayId":"KRAS SIGNALING DN","pathwayName":"KRAS SIGNALING DN","topLevelPathway":"Signaling"}
{"pathwayId":"KRAS SIGNALING UP","pathwayName":"KRAS SIGNALING UP","topLevelPathway":"Signaling"}
{"pathwayId":"MITOTIC SPINDLE","pathwayName":"MITOTIC SPINDLE","topLevelPathway":"Growth"}
{"pathwayId":"MTORC1 SIGNALING","pathwayName":"MTORC1 SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"MYC TARGETS V1","pathwayName":"MYC TARGETS V1","topLevelPathway":"Growth"}
{"pathwayId":"MYC TARGETS V2","pathwayName":"MYC TARGETS V2","topLevelPathway":"Growth"}
{"pathwayId":"MYOGENESIS","pathwayName":"MYOGENESIS","topLevelPathway":"Development"}
{"pathwayId":"NOTCH SIGNALING","pathwayName":"NOTCH SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"OXIDATIVE PHOSPHORYLATION","pathwayName":"OXIDATIVE PHOSPHORYLATION","topLevelPathway":"Metabolic"}
{"pathwayId":"P53 PATHWAY","pathwayName":"P53 PATHWAY","topLevelPathway":"Growth"}
{"pathwayId":"PANCREAS BETA CELLS","pathwayName":"PANCREAS BETA CELLS","topLevelPathway":"Development"}
{"pathwayId":"PEROXISOME","pathwayName":"PEROXISOME","topLevelPathway":"Cellular"}
{"pathwayId":"PI3K AKT MTOR SIGNALING","pathwayName":"PI3K AKT MTOR SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"PROTEIN SECRETION","pathwayName":"PROTEIN SECRETION","topLevelPathway":"Stress"}
{"pathwayId":"REACTIVE OXYGEN SPECIES PATHWAY","pathwayName":"REACTIVE OXYGEN SPECIES PATHWAY","topLevelPathway":"Stress"}
{"pathwayId":"SPERMATOGENESIS","pathwayName":"SPERMATOGENESIS","topLevelPathway":"Development"}
{"pathwayId":"TGF BETA SIGNALING","pathwayName":"TGF BETA SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"TNFA SIGNALING VIA NFKB","pathwayName":"TNFA SIGNALING VIA NFKB","topLevelPathway":"Signaling"}
{"pathwayId":"UNFOLDED PROTEIN RESPONSE","pathwayName":"UNFOLDED PROTEIN RESPONSE","topLevelPathway":"Stress"}
{"pathwayId":"UV RESPONSE DN","pathwayName":"UV RESPONSE DN","topLevelPathway":"DNA Damage"}
{"pathwayId":"UV RESPONSE UP","pathwayName":"UV RESPONSE UP","topLevelPathway":"DNA Damage"}
{"pathwayId":"WNT BETA CATENIN SIGNALING","pathwayName":"WNT BETA CATENIN SIGNALING","topLevelPathway":"Signaling"}
{"pathwayId":"XENOBIOTIC METABOLISM","pathwayName":"XENOBIOTIC METABOLISM","topLevelPathway":"Metabolic"}
{"pathwayId":"hsa01100","pathwayName":"Metabolic pathways","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01110","pathwayName":"Biosynthesis of secondary metabolites","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01120","pathwayName":"Microbial metabolism in diverse environments","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01200","pathwayName":"Carbon metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01210","pathwayName":"2-Oxocarboxylic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01212","pathwayName":"Fatty acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01230","pathwayName":"Biosynthesis of amino acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01232","pathwayName":"Nucleotide metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01250","pathwayName":"Biosynthesis of nucleotide sugars","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01240","pathwayName":"Biosynthesis of cofactors","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01220","pathwayName":"Degradation of aromatic compounds","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00010","pathwayName":"Glycolysis / Gluconeogenesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00020","pathwayName":"Citrate cycle (TCA cycle)","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00030","pathwayName":"Pentose phosphate pathway","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00040","pathwayName":"Pentose and glucuronate interconversions","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00051","pathwayName":"Fructose and mannose metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00052","pathwayName":"Galactose metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00053","pathwayName":"Ascorbate and aldarate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00500","pathwayName":"Starch and sucrose metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00520","pathwayName":"Amino sugar and nucleotide sugar metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00620","pathwayName":"Pyruvate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00630","pathwayName":"Glyoxylate and dicarboxylate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00640","pathwayName":"Propanoate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00650","pathwayName":"Butanoate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00660","pathwayName":"C5-Branched dibasic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00562","pathwayName":"Inositol phosphate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00190","pathwayName":"Oxidative phosphorylation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00195","pathwayName":"Photosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00196","pathwayName":"Photosynthesis - antenna proteins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00710","pathwayName":"Carbon fixation in photosynthetic organisms","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00720","pathwayName":"Carbon fixation pathways in prokaryotes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00680","pathwayName":"Methane metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00910","pathwayName":"Nitrogen metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00920","pathwayName":"Sulfur metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00061","pathwayName":"Fatty acid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00062","pathwayName":"Fatty acid elongation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00071","pathwayName":"Fatty acid degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00073","pathwayName":"Cutin, suberine and wax biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00100","pathwayName":"Steroid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00120","pathwayName":"Primary bile acid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00121","pathwayName":"Secondary bile acid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00140","pathwayName":"Steroid hormone biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00561","pathwayName":"Glycerolipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00564","pathwayName":"Glycerophospholipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00565","pathwayName":"Ether lipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00600","pathwayName":"Sphingolipid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00590","pathwayName":"Arachidonic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00591","pathwayName":"Linoleic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00592","pathwayName":"alpha-Linolenic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01040","pathwayName":"Biosynthesis of unsaturated fatty acids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00230","pathwayName":"Purine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00240","pathwayName":"Pyrimidine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00250","pathwayName":"Alanine, aspartate and glutamate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00260","pathwayName":"Glycine, serine and threonine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00270","pathwayName":"Cysteine and methionine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00280","pathwayName":"Valine, leucine and isoleucine degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00290","pathwayName":"Valine, leucine and isoleucine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00300","pathwayName":"Lysine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00310","pathwayName":"Lysine degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00220","pathwayName":"Arginine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00330","pathwayName":"Arginine and proline metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00340","pathwayName":"Histidine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00350","pathwayName":"Tyrosine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00360","pathwayName":"Phenylalanine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00380","pathwayName":"Tryptophan metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00400","pathwayName":"Phenylalanine, tyrosine and tryptophan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00410","pathwayName":"beta-Alanine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00430","pathwayName":"Taurine and hypotaurine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00440","pathwayName":"Phosphonate and phosphinate metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00450","pathwayName":"Selenocompound metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00460","pathwayName":"Cyanoamino acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00470","pathwayName":"D-Amino acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00480","pathwayName":"Glutathione metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00510","pathwayName":"N-Glycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00513","pathwayName":"Various types of N-glycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00512","pathwayName":"Mucin type O-glycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00515","pathwayName":"Mannose type O-glycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00514","pathwayName":"Other types of O-glycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00532","pathwayName":"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00534","pathwayName":"Glycosaminoglycan biosynthesis - heparan sulfate / heparin","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00533","pathwayName":"Glycosaminoglycan biosynthesis - keratan sulfate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00531","pathwayName":"Glycosaminoglycan degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00563","pathwayName":"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00601","pathwayName":"Glycosphingolipid biosynthesis - lacto and neolacto series","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00603","pathwayName":"Glycosphingolipid biosynthesis - globo and isoglobo series","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00604","pathwayName":"Glycosphingolipid biosynthesis - ganglio series","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00511","pathwayName":"Other glycan degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00540","pathwayName":"Lipopolysaccharide biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00542","pathwayName":"O-Antigen repeat unit biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00541","pathwayName":"O-Antigen nucleotide sugar biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00550","pathwayName":"Peptidoglycan biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00552","pathwayName":"Teichoic acid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00571","pathwayName":"Lipoarabinomannan (LAM) biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00572","pathwayName":"Arabinogalactan biosynthesis - Mycobacterium","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00543","pathwayName":"Exopolysaccharide biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00730","pathwayName":"Thiamine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00740","pathwayName":"Riboflavin metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00750","pathwayName":"Vitamin B6 metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00760","pathwayName":"Nicotinate and nicotinamide metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00770","pathwayName":"Pantothenate and CoA biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00780","pathwayName":"Biotin metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00785","pathwayName":"Lipoic acid metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00790","pathwayName":"Folate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00670","pathwayName":"One carbon pool by folate","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00830","pathwayName":"Retinol metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00860","pathwayName":"Porphyrin metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00130","pathwayName":"Ubiquinone and other terpenoid-quinone biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00900","pathwayName":"Terpenoid backbone biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00902","pathwayName":"Monoterpenoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00909","pathwayName":"Sesquiterpenoid and triterpenoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00904","pathwayName":"Diterpenoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00906","pathwayName":"Carotenoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00905","pathwayName":"Brassinosteroid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00981","pathwayName":"Insect hormone biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00908","pathwayName":"Zeatin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00903","pathwayName":"Limonene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00907","pathwayName":"Pinene, camphor and geraniol degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01052","pathwayName":"Type I polyketide structures","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00522","pathwayName":"Biosynthesis of 12-, 14- and 16-membered macrolides","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01051","pathwayName":"Biosynthesis of ansamycins","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01059","pathwayName":"Biosynthesis of enediyne antibiotics","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01056","pathwayName":"Biosynthesis of type II polyketide backbone","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01057","pathwayName":"Biosynthesis of type II polyketide products","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00253","pathwayName":"Tetracycline biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00523","pathwayName":"Polyketide sugar unit biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01054","pathwayName":"Nonribosomal peptide structures","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01053","pathwayName":"Biosynthesis of siderophore group nonribosomal peptides","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01055","pathwayName":"Biosynthesis of vancomycin group antibiotics","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00940","pathwayName":"Phenylpropanoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00945","pathwayName":"Stilbenoid, diarylheptanoid and gingerol biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00941","pathwayName":"Flavonoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00944","pathwayName":"Flavone and flavonol biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00942","pathwayName":"Anthocyanin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00943","pathwayName":"Isoflavonoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00946","pathwayName":"Degradation of flavonoids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00901","pathwayName":"Indole alkaloid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00403","pathwayName":"Indole diterpene alkaloid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00950","pathwayName":"Isoquinoline alkaloid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00960","pathwayName":"Tropane, piperidine and pyridine alkaloid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00996","pathwayName":"Biosynthesis of various alkaloids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00232","pathwayName":"Caffeine metabolism","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00965","pathwayName":"Betalain biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00966","pathwayName":"Glucosinolate biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00402","pathwayName":"Benzoxazinoid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00311","pathwayName":"Penicillin and cephalosporin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00332","pathwayName":"Carbapenem biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00261","pathwayName":"Monobactam biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00331","pathwayName":"Clavulanic acid biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00521","pathwayName":"Streptomycin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00524","pathwayName":"Neomycin, kanamycin and gentamicin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00525","pathwayName":"Acarbose and validamycin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00401","pathwayName":"Novobiocin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00404","pathwayName":"Staurosporine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00405","pathwayName":"Phenazine biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00333","pathwayName":"Prodigiosin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00254","pathwayName":"Aflatoxin biosynthesis","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00998","pathwayName":"Biosynthesis of various antibiotics","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00999","pathwayName":"Biosynthesis of various plant secondary metabolites","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00997","pathwayName":"Biosynthesis of various other secondary metabolites","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00362","pathwayName":"Benzoate degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00627","pathwayName":"Aminobenzoate degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00364","pathwayName":"Fluorobenzoate degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00625","pathwayName":"Chloroalkane and chloroalkene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00361","pathwayName":"Chlorocyclohexane and chlorobenzene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00623","pathwayName":"Toluene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00622","pathwayName":"Xylene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00633","pathwayName":"Nitrotoluene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00642","pathwayName":"Ethylbenzene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00643","pathwayName":"Styrene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00791","pathwayName":"Atrazine degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00930","pathwayName":"Caprolactam degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00363","pathwayName":"Bisphenol degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00621","pathwayName":"Dioxin degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00626","pathwayName":"Naphthalene degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00624","pathwayName":"Polycyclic aromatic hydrocarbon degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00365","pathwayName":"Furfural degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00984","pathwayName":"Steroid degradation","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00980","pathwayName":"Metabolism of xenobiotics by cytochrome P450","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00982","pathwayName":"Drug metabolism - cytochrome P450","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa00983","pathwayName":"Drug metabolism - other enzymes","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01010","pathwayName":"Overview of biosynthetic pathways","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01060","pathwayName":"Biosynthesis of plant secondary metabolites","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01061","pathwayName":"Biosynthesis of phenylpropanoids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01062","pathwayName":"Biosynthesis of terpenoids and steroids","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01063","pathwayName":"Biosynthesis of alkaloids derived from shikimate pathway","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01064","pathwayName":"Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01065","pathwayName":"Biosynthesis of alkaloids derived from histidine and purine","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01066","pathwayName":"Biosynthesis of alkaloids derived from terpenoid and polyketide","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa01070","pathwayName":"Biosynthesis of plant hormones","topLevelPathway":"Metabolism","groupedPathway":"Metabolism"}
{"pathwayId":"hsa03020","pathwayName":"RNA polymerase","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03022","pathwayName":"Basal transcription factors","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03040","pathwayName":"Spliceosome","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03010","pathwayName":"Ribosome","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa00970","pathwayName":"Aminoacyl-tRNA biosynthesis","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03013","pathwayName":"Nucleocytoplasmic transport","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03015","pathwayName":"mRNA surveillance pathway","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03008","pathwayName":"Ribosome biogenesis in eukaryotes","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03060","pathwayName":"Protein export","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa04141","pathwayName":"Protein processing in endoplasmic reticulum","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa04130","pathwayName":"SNARE interactions in vesicular transport","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa04120","pathwayName":"Ubiquitin mediated proteolysis","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa04122","pathwayName":"Sulfur relay system","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03050","pathwayName":"Proteasome","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03018","pathwayName":"RNA degradation","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03030","pathwayName":"DNA replication","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03410","pathwayName":"Base excision repair","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03420","pathwayName":"Nucleotide excision repair","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03430","pathwayName":"Mismatch repair","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03440","pathwayName":"Homologous recombination","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03450","pathwayName":"Non-homologous end-joining","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03460","pathwayName":"Fanconi anemia pathway","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03082","pathwayName":"ATP-dependent chromatin remodeling","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03083","pathwayName":"Polycomb repressive complex","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03230","pathwayName":"Viral genome structure","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03240","pathwayName":"Viral replication","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03250","pathwayName":"Viral life cycle - HIV-1","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03260","pathwayName":"Virion - Human immunodeficiency virus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03271","pathwayName":"Virion - Rotavirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03262","pathwayName":"Virion - Coronavirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03261","pathwayName":"Virion - Influenza virus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03263","pathwayName":"Virion - Enterovirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03264","pathwayName":"Virion - Flavivirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03265","pathwayName":"Virion - Ebolavirus, Lyssavirus and Morbillivirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03266","pathwayName":"Virion - Herpesvirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03268","pathwayName":"Virion - Orthopoxvirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03267","pathwayName":"Virion - Adenovirus","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03259","pathwayName":"Virion - Bacteriophages T4 and T7","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa03258","pathwayName":"Virion - Bacteriophage lambda","topLevelPathway":"Genetic Information Processing","groupedPathway":"Genetic Information Processing"}
{"pathwayId":"hsa02010","pathwayName":"ABC transporters","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa02060","pathwayName":"Phosphotransferase system (PTS)","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa03070","pathwayName":"Bacterial secretion system","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa02020","pathwayName":"Two-component system","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04010","pathwayName":"MAPK signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04013","pathwayName":"MAPK signaling pathway - fly","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04016","pathwayName":"MAPK signaling pathway - plant","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04011","pathwayName":"MAPK signaling pathway - yeast","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04012","pathwayName":"ErbB signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04014","pathwayName":"Ras signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04015","pathwayName":"Rap1 signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04310","pathwayName":"Wnt signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04330","pathwayName":"Notch signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04340","pathwayName":"Hedgehog signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04341","pathwayName":"Hedgehog signaling pathway - fly","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04350","pathwayName":"TGF-beta signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04390","pathwayName":"Hippo signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04391","pathwayName":"Hippo signaling pathway - fly","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04392","pathwayName":"Hippo signaling pathway - multiple species","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04370","pathwayName":"VEGF signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04371","pathwayName":"Apelin signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04630","pathwayName":"JAK-STAT signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04064","pathwayName":"NF-kappa B signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04668","pathwayName":"TNF signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04066","pathwayName":"HIF-1 signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04068","pathwayName":"FoxO signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04020","pathwayName":"Calcium signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04070","pathwayName":"Phosphatidylinositol signaling system","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04072","pathwayName":"Phospholipase D signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04071","pathwayName":"Sphingolipid signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04024","pathwayName":"cAMP signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04022","pathwayName":"cGMP-PKG signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04151","pathwayName":"PI3K-Akt signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04152","pathwayName":"AMPK signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04150","pathwayName":"mTOR signaling pathway","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04075","pathwayName":"Plant hormone signal transduction","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04080","pathwayName":"Neuroactive ligand-receptor interaction","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04060","pathwayName":"Cytokine-cytokine receptor interaction","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04061","pathwayName":"Viral protein interaction with cytokine and cytokine receptor","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04512","pathwayName":"ECM-receptor interaction","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04514","pathwayName":"Cell adhesion molecules","topLevelPathway":"Environmental Information Processing","groupedPathway":"Environmental Information Processing"}
{"pathwayId":"hsa04144","pathwayName":"Endocytosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04145","pathwayName":"Phagosome","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04142","pathwayName":"Lysosome","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04146","pathwayName":"Peroxisome","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04140","pathwayName":"Autophagy - animal","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04138","pathwayName":"Autophagy - yeast","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04136","pathwayName":"Autophagy - other","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04137","pathwayName":"Mitophagy - animal","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04139","pathwayName":"Mitophagy - yeast","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04148","pathwayName":"Efferocytosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04110","pathwayName":"Cell cycle","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04111","pathwayName":"Cell cycle - yeast","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04112","pathwayName":"Cell cycle - Caulobacter","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04113","pathwayName":"Meiosis - yeast","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04114","pathwayName":"Oocyte meiosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04210","pathwayName":"Apoptosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04214","pathwayName":"Apoptosis - fly","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04215","pathwayName":"Apoptosis - multiple species","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04216","pathwayName":"Ferroptosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04217","pathwayName":"Necroptosis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04115","pathwayName":"p53 signaling pathway","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04218","pathwayName":"Cellular senescence","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04510","pathwayName":"Focal adhesion","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04520","pathwayName":"Adherens junction","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04530","pathwayName":"Tight junction","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04540","pathwayName":"Gap junction","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04550","pathwayName":"Signaling pathways regulating pluripotency of stem cells","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa02024","pathwayName":"Quorum sensing","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa05111","pathwayName":"Biofilm formation - Vibrio cholerae","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa02025","pathwayName":"Biofilm formation - Pseudomonas aeruginosa","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa02026","pathwayName":"Biofilm formation - Escherichia coli","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa02030","pathwayName":"Bacterial chemotaxis","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa02040","pathwayName":"Flagellar assembly","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04814","pathwayName":"Motor proteins","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04820","pathwayName":"Cytoskeleton in muscle cells","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04810","pathwayName":"Regulation of actin cytoskeleton","topLevelPathway":"Cellular Processes","groupedPathway":"Cellular Processes"}
{"pathwayId":"hsa04640","pathwayName":"Hematopoietic cell lineage","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04610","pathwayName":"Complement and coagulation cascades","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04611","pathwayName":"Platelet activation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04613","pathwayName":"Neutrophil extracellular trap formation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04620","pathwayName":"Toll-like receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04624","pathwayName":"Toll and Imd signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04621","pathwayName":"NOD-like receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04622","pathwayName":"RIG-I-like receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04623","pathwayName":"Cytosolic DNA-sensing pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04625","pathwayName":"C-type lectin receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04650","pathwayName":"Natural killer cell mediated cytotoxicity","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04612","pathwayName":"Antigen processing and presentation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04660","pathwayName":"T cell receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04658","pathwayName":"Th1 and Th2 cell differentiation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04659","pathwayName":"Th17 cell differentiation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04657","pathwayName":"IL-17 signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04662","pathwayName":"B cell receptor signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04664","pathwayName":"Fc epsilon RI signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04666","pathwayName":"Fc gamma R-mediated phagocytosis","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04670","pathwayName":"Leukocyte transendothelial migration","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04672","pathwayName":"Intestinal immune network for IgA production","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04062","pathwayName":"Chemokine signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04911","pathwayName":"Insulin secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04910","pathwayName":"Insulin signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04922","pathwayName":"Glucagon signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04923","pathwayName":"Regulation of lipolysis in adipocytes","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04920","pathwayName":"Adipocytokine signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa03320","pathwayName":"PPAR signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04929","pathwayName":"GnRH secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04912","pathwayName":"GnRH signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04913","pathwayName":"Ovarian steroidogenesis","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04915","pathwayName":"Estrogen signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04914","pathwayName":"Progesterone-mediated oocyte maturation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04917","pathwayName":"Prolactin signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04921","pathwayName":"Oxytocin signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04926","pathwayName":"Relaxin signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04935","pathwayName":"Growth hormone synthesis, secretion and action","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04918","pathwayName":"Thyroid hormone synthesis","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04919","pathwayName":"Thyroid hormone signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04928","pathwayName":"Parathyroid hormone synthesis, secretion and action","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04916","pathwayName":"Melanogenesis","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04924","pathwayName":"Renin secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04614","pathwayName":"Renin-angiotensin system","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04925","pathwayName":"Aldosterone synthesis and secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04927","pathwayName":"Cortisol synthesis and secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04260","pathwayName":"Cardiac muscle contraction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04261","pathwayName":"Adrenergic signaling in cardiomyocytes","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04270","pathwayName":"Vascular smooth muscle contraction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04970","pathwayName":"Salivary secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04971","pathwayName":"Gastric acid secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04972","pathwayName":"Pancreatic secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04976","pathwayName":"Bile secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04973","pathwayName":"Carbohydrate digestion and absorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04974","pathwayName":"Protein digestion and absorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04975","pathwayName":"Fat digestion and absorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04979","pathwayName":"Cholesterol metabolism","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04977","pathwayName":"Vitamin digestion and absorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04980","pathwayName":"Cobalamin transport and metabolism","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04978","pathwayName":"Mineral absorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04962","pathwayName":"Vasopressin-regulated water reabsorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04960","pathwayName":"Aldosterone-regulated sodium reabsorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04961","pathwayName":"Endocrine and other factor-regulated calcium reabsorption","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04964","pathwayName":"Proximal tubule bicarbonate reclamation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04966","pathwayName":"Collecting duct acid secretion","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04724","pathwayName":"Glutamatergic synapse","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04727","pathwayName":"GABAergic synapse","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04725","pathwayName":"Cholinergic synapse","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04728","pathwayName":"Dopaminergic synapse","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04726","pathwayName":"Serotonergic synapse","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04720","pathwayName":"Long-term potentiation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04730","pathwayName":"Long-term depression","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04723","pathwayName":"Retrograde endocannabinoid signaling","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04721","pathwayName":"Synaptic vesicle cycle","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04722","pathwayName":"Neurotrophin signaling pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04744","pathwayName":"Phototransduction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04745","pathwayName":"Phototransduction - fly","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04740","pathwayName":"Olfactory transduction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04742","pathwayName":"Taste transduction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04750","pathwayName":"Inflammatory mediator regulation of TRP channels","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04320","pathwayName":"Dorso-ventral axis formation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04360","pathwayName":"Axon guidance","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04361","pathwayName":"Axon regeneration","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04380","pathwayName":"Osteoclast differentiation","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04211","pathwayName":"Longevity regulating pathway","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04212","pathwayName":"Longevity regulating pathway - worm","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04213","pathwayName":"Longevity regulating pathway - multiple species","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04710","pathwayName":"Circadian rhythm","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04713","pathwayName":"Circadian entrainment","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04711","pathwayName":"Circadian rhythm - fly","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04712","pathwayName":"Circadian rhythm - plant","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04714","pathwayName":"Thermogenesis","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa04626","pathwayName":"Plant-pathogen interaction","topLevelPathway":"Organismal Systems","groupedPathway":"Organismal Systems"}
{"pathwayId":"hsa05200","pathwayName":"Pathways in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05202","pathwayName":"Transcriptional misregulation in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05206","pathwayName":"MicroRNAs in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05205","pathwayName":"Proteoglycans in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05204","pathwayName":"Chemical carcinogenesis - DNA adducts","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05207","pathwayName":"Chemical carcinogenesis - receptor activation","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05208","pathwayName":"Chemical carcinogenesis - reactive oxygen species","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05203","pathwayName":"Viral carcinogenesis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05230","pathwayName":"Central carbon metabolism in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05231","pathwayName":"Choline metabolism in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05235","pathwayName":"PD-L1 expression and PD-1 checkpoint pathway in cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05210","pathwayName":"Colorectal cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05212","pathwayName":"Pancreatic cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05225","pathwayName":"Hepatocellular carcinoma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05226","pathwayName":"Gastric cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05214","pathwayName":"Glioma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05216","pathwayName":"Thyroid cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05221","pathwayName":"Acute myeloid leukemia","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05220","pathwayName":"Chronic myeloid leukemia","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05217","pathwayName":"Basal cell carcinoma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05218","pathwayName":"Melanoma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05211","pathwayName":"Renal cell carcinoma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05219","pathwayName":"Bladder cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05215","pathwayName":"Prostate cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05213","pathwayName":"Endometrial cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05224","pathwayName":"Breast cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05222","pathwayName":"Small cell lung cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05223","pathwayName":"Non-small cell lung cancer","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05166","pathwayName":"Human T-cell leukemia virus 1 infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05170","pathwayName":"Human immunodeficiency virus 1 infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05161","pathwayName":"Hepatitis B","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05160","pathwayName":"Hepatitis C","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05171","pathwayName":"Coronavirus disease - COVID-19","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05164","pathwayName":"Influenza A","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05162","pathwayName":"Measles","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05168","pathwayName":"Herpes simplex virus 1 infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05163","pathwayName":"Human cytomegalovirus infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05167","pathwayName":"Kaposi sarcoma-associated herpesvirus infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05169","pathwayName":"Epstein-Barr virus infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05165","pathwayName":"Human papillomavirus infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05110","pathwayName":"Vibrio cholerae infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05120","pathwayName":"Epithelial cell signaling in Helicobacter pylori infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05130","pathwayName":"Pathogenic Escherichia coli infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05132","pathwayName":"Salmonella infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05131","pathwayName":"Shigellosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05135","pathwayName":"Yersinia infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05133","pathwayName":"Pertussis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05134","pathwayName":"Legionellosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05150","pathwayName":"Staphylococcus aureus infection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05152","pathwayName":"Tuberculosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05100","pathwayName":"Bacterial invasion of epithelial cells","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05146","pathwayName":"Amoebiasis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05144","pathwayName":"Malaria","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05145","pathwayName":"Toxoplasmosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05140","pathwayName":"Leishmaniasis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05142","pathwayName":"Chagas disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05143","pathwayName":"African trypanosomiasis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05310","pathwayName":"Asthma","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05322","pathwayName":"Systemic lupus erythematosus","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05323","pathwayName":"Rheumatoid arthritis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05320","pathwayName":"Autoimmune thyroid disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05321","pathwayName":"Inflammatory bowel disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05330","pathwayName":"Allograft rejection","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05332","pathwayName":"Graft-versus-host disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05340","pathwayName":"Primary immunodeficiency","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05010","pathwayName":"Alzheimer disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05012","pathwayName":"Parkinson disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05014","pathwayName":"Amyotrophic lateral sclerosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05016","pathwayName":"Huntington disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05017","pathwayName":"Spinocerebellar ataxia","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05020","pathwayName":"Prion disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05022","pathwayName":"Pathways of neurodegeneration - multiple diseases","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05030","pathwayName":"Cocaine addiction","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05031","pathwayName":"Amphetamine addiction","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05032","pathwayName":"Morphine addiction","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05033","pathwayName":"Nicotine addiction","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05034","pathwayName":"Alcoholism","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05417","pathwayName":"Lipid and atherosclerosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05418","pathwayName":"Fluid shear stress and atherosclerosis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05410","pathwayName":"Hypertrophic cardiomyopathy","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05412","pathwayName":"Arrhythmogenic right ventricular cardiomyopathy","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05414","pathwayName":"Dilated cardiomyopathy","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05415","pathwayName":"Diabetic cardiomyopathy","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa05416","pathwayName":"Viral myocarditis","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04930","pathwayName":"Type II diabetes mellitus","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04940","pathwayName":"Type I diabetes mellitus","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04950","pathwayName":"Maturity onset diabetes of the young","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04936","pathwayName":"Alcoholic liver disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04932","pathwayName":"Non-alcoholic fatty liver disease","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04931","pathwayName":"Insulin resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04933","pathwayName":"AGE-RAGE signaling pathway in diabetic complications","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa04934","pathwayName":"Cushing syndrome","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01501","pathwayName":"beta-Lactam resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01502","pathwayName":"Vancomycin resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01503","pathwayName":"Cationic antimicrobial peptide (CAMP) resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01521","pathwayName":"EGFR tyrosine kinase inhibitor resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01524","pathwayName":"Platinum drug resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01523","pathwayName":"Antifolate resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa01522","pathwayName":"Endocrine resistance","topLevelPathway":"Human Diseases","groupedPathway":"Human Diseases"}
{"pathwayId":"hsa07011","pathwayName":"Penicillins","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07012","pathwayName":"Cephalosporins - parenteral agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07013","pathwayName":"Cephalosporins - oral agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07021","pathwayName":"Aminoglycosides","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07019","pathwayName":"Tetracyclines","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07020","pathwayName":"Macrolides and ketolides","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07014","pathwayName":"Quinolones","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07023","pathwayName":"Rifamycins","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07026","pathwayName":"Antifungal agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07044","pathwayName":"Antiviral agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07053","pathwayName":"Anti-HIV agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07040","pathwayName":"Antineoplastics - alkylating agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07041","pathwayName":"Antineoplastics - antimetabolic agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07042","pathwayName":"Antineoplastics - agents from natural products","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07043","pathwayName":"Antineoplastics - hormones","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07045","pathwayName":"Antineoplastics - protein kinase inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07032","pathwayName":"Hypnotics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07030","pathwayName":"Anxiolytics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07033","pathwayName":"Anticonvulsants","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07015","pathwayName":"Local analgesics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07039","pathwayName":"Opioid analgesics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07028","pathwayName":"Antipsychotics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07029","pathwayName":"Antipsychotics - phenothiazines","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07031","pathwayName":"Antipsychotics - butyrophenones","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07027","pathwayName":"Antidepressants","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07056","pathwayName":"Agents for Alzheimer-type dementia","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07057","pathwayName":"Antiparkinsonian agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07055","pathwayName":"Sulfonamide derivatives - overview","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07016","pathwayName":"Sulfonamide derivatives - sulfa drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07017","pathwayName":"Sulfonamide derivatives - diuretics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07018","pathwayName":"Sulfonamide derivatives - hypoglycemic agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07037","pathwayName":"Antiarrhythmic drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07038","pathwayName":"Antiulcer drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07046","pathwayName":"Immunosuppressive agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07047","pathwayName":"Osteoporosis drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07048","pathwayName":"Antimigraines","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07049","pathwayName":"Antithrombosis agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07050","pathwayName":"Antirheumatics - DMARDs and biological agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07051","pathwayName":"Antidiabetics","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07052","pathwayName":"Antidyslipidemic agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07054","pathwayName":"Antiglaucoma agents","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07220","pathwayName":"Cholinergic and anticholinergic drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07215","pathwayName":"alpha-Adrenergic receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07214","pathwayName":"beta-Adrenergic receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07213","pathwayName":"Dopamine receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07212","pathwayName":"Histamine H1 receptor antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07227","pathwayName":"Histamine H2/H3 receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07211","pathwayName":"Serotonin receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07228","pathwayName":"Eicosanoid receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07224","pathwayName":"Opioid receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07229","pathwayName":"Angiotensin receptor and endothelin receptor antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07225","pathwayName":"Glucocorticoid and mineralocorticoid receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07226","pathwayName":"Progesterone, androgen and estrogen receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07223","pathwayName":"Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07222","pathwayName":"Peroxisome proliferator-activated receptor (PPAR) agonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07221","pathwayName":"Nicotinic cholinergic receptor antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07230","pathwayName":"GABA-A receptor agonists/antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07036","pathwayName":"Calcium channel blocking drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07231","pathwayName":"Sodium channel blocking drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07232","pathwayName":"Potassium channel blocking and opening drugs","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07235","pathwayName":"N-Methyl-D-aspartic acid (NMDA) receptor antagonists","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07233","pathwayName":"Ion transporter inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07234","pathwayName":"Neurotransmitter transporter inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07216","pathwayName":"Catecholamine transferase inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07219","pathwayName":"Cyclooxygenase inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07024","pathwayName":"HMG-CoA reductase inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07217","pathwayName":"Renin-angiotensin system inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07218","pathwayName":"HIV protease inhibitors","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07025","pathwayName":"Quinolines","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07034","pathwayName":"Eicosanoids","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07035","pathwayName":"Prostaglandins","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07110","pathwayName":"Benzoic acid family","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07112","pathwayName":"1,2-Diphenyl substitution family","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07114","pathwayName":"Naphthalene family","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}
{"pathwayId":"hsa07117","pathwayName":"Benzodiazepine family","topLevelPathway":"Drug Development","groupedPathway":"Drug Development"}