Package: panoramic Title: Variance-Aware Multi-Sample Spatial Colocalization Analysis Version: 0.99.4 Authors@R: person("Jacob", "Chang", email = "jachang4@stanford.edu", role = c("aut", "cre", "fnd"), comment = c(ORCID = "0000-0002-3719-7949")) Description: Quantifies and compares cell-type spatial colocalization across samples, patients, and conditions in spatial omics studies. Its primary statistic, edge-corrected local competition enrichment, measures excess or deficit local mixing for ordered cell-type pairs on a percentage-point scale. The package estimates within-sample uncertainty with spatial bootstrap procedures and propagates it through multilevel random-effects meta-analysis for pooled inference and group-level contrasts; classical spatial summary statistics are also supported. URL: https://github.com/plevritis-lab/panoramic BugReports: https://github.com/plevritis-lab/panoramic/issues License: MIT + file LICENSE Depends: R (>= 4.5) Imports: dplyr, ggplot2, ggrepel, igraph, tidygraph, ggraph, rlang, S4Vectors, SummarizedExperiment, spatstat.geom, spatstat.explore, BiocParallel, SpatialExperiment, concaveman, metafor, withr, matrixStats Suggests: knitr, markdown, rmarkdown, BiocStyle, testthat (>= 3.0.0) VignetteBuilder: knitr Config/testthat/edition: 3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.3.3 biocViews: Software, Spatial, SingleCell Config/pak/sysreqs: libabsl-dev cmake libfontconfig1-dev libfreetype6-dev libgdal-dev gdal-bin libgeos-dev libglpk-dev libmagick++-dev gsfonts libicu-dev libxml2-dev libssl-dev libproj-dev libsqlite3-dev libudunits2-dev libnode-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-09-28 22:59:20 UTC RemoteUrl: https://github.com/bioc/panoramic RemoteRef: HEAD RemoteSha: d45f4c84fb293268a4220b6bf7ae93b4f9e7eea0 NeedsCompilation: no Packaged: 2026-09-29 02:17:47 UTC; root Author: Jacob Chang [aut, cre, fnd] (ORCID: ) Maintainer: Jacob Chang