NEWS
orthogene 1.7.2
Bug fixes
orthogene 1.7.1
New features
remove_all_nas
- Can handle multiple cols.
plot_orthotree
- New arg
clades_rotate
- New func:
rotate_clades
Bug fixes
add_columns
- Handle both vectors and columns.
sort_rows_func
- Handle both vectors and columns.
filter_gene_df
- Avoid coercing single-col dataframe into vector.
- Flagged in #34
- Fix
test-report_orthologs
- Recognize either Gene.symbol or input_gene cols
depending on when ortholog conversion was done.
- Fix
test-convert_orthologs
- Line 99 test had wrong number of cols.
map_genes_planosphere
- Add backup download strategy.
orthogene 1.7.0
New features
orthogene 1.5.3
New features
convert_orthologs
- Can now take a user-supplied gene_map to use instead of gprofiler/homologene/babelgene.
- Lets user take advantage of all of the many:many ortholog mapping functions for organisms
not covered in any of the databases (eg. earthworm).
- New helper function:
set_gprofiler
(to use beta version)
map_genes
- Can now translate planarian gene synonyms
using subfunction:
map_genes_planosphere
.
Bug fixes
convert_orthologs
- Now returns original data when
input_species
==output
species
(after performing method-specific species mapping) AND standardise_genes==FALSE
.
add_synonyms
- When
syn_map
is NULL
, will use the gene_map
instead.
map_orthologs_custom
- Remove
if(input_species==output_species) return(NULL)
drop_non121
- Don't run grouped slicing when "input_gene","ortholog_gene" are the only cols.
orthogene 1.5.2
New features
- Remove unnecessary Suggests
map_species
get_all_orgs
: When species=NULL
, now returns an extra columns called
"scientific_name_formatted".
format_species_name
: New args
remove_parentheses
, remove_subspecies
, remove_subspecies_exceptions
report_orthologs
- Make much more efficient by only querying
ref_genes
once.
- Added new internal func
report_orthologs_i
instead of recursion to make this easier.
- Ensure that
map
and report
get rbound separately and returned
according to the return_report
arg.
format_species
- Export function that was previously named
format_species_name
.
all_species
:
- New exported function
- Originally implemented a version of this in
EWCE::list_species
,
but decided to extend it and export it here.
get_silhouettes
- Previously was internal func:
gather_images
.
- Now an exported function.
plot_orthotree
- Add "Invertebrates" to default
clades
- Update README to showcase more functions.
Bug fixes
drop_non121
- New arg
symbol_only
to ONLY consider gene symbols (not ensemble IDs)
when identifying non-121 orthologs.
- This make a drastic difference in the number of 1:1 orthologs that get dropped!
gather_images
- Update to use newly released
rphylopic
1.0.0
which uses the new phylopic API.
- Add another
tryCatch
for when the SVG is available but not the png.
is_human
- Add "9606" and "homo sapiens sapiens" species ID to list of options.
all_genes_babelgene
- Don't filter by support when speices is human,
because this column will always be
NA
since it's irrelevant for humans.
- Fix unit tests:
dMcast
- Fix
stats::pass
--> stats::na.pass
. Weirdly, only a problem on Linux.
Did base R change a fundamental function name?
orthogene 1.5.1
New features
- Bumped to 1.5.1 for Bioc devel 3.17
- Merged upstream devel.
- Now using
rworkflows
for GHA.
- Host
orthogene
data resources on Zenodo:
- https://doi.org/10.5281/zenodo.7315418
- Upgrade TimeTree phylogeny to v5 (2022):
- 50k+ species --> 137k+ species!
- Replace
dplyr::%>%
usage with |>
- Add CITATION file
Bug fixes
prepare_tree
:
- Ignore species name case and trim "'" when filtering tree.
map_species
:
- Add
trimws
step to remove flanking " " or "'".
orthogene 1.3.4
Bug fixes
- Remove
Matrix.utils
since it's now deprecated.
- Reimplement the
dMcast
function as a new internal function within
orthogene
, since that's the only function I use from Matrix.utils
.
- Fix GHA workflow now that r-lib/actions@master has been removed.
orthogene 1.3.3
Bug fixes
- Make
test-map_orthologs_babelgene
less stringent with the
number of genes expected.
orthogene 1.3.2
New features
- Add inst/grofiler_namespace.csv.gz for documentation purposes.
Bug fixes
create_background
:
- Ensure user-supplied
bg
gets used:
https://github.com/neurogenomics/orthogene/issues/22
- Properly document internal data so that
devtools::document
doesn't expect them to be exported objects.
orthogene 1.3.1
New features
plot_orthotree
: Pass up tree_source
arg.
orthogene 1.3.0
New features
aggregate_mapped_genes
:
- Pass up additional args from
map_genes
.
- Add
map_orthologs
as a way to create gene_map
automatically,
when gene_map=NULL
and input_species!=output_species
.
- Split
species
into input_species
and output_species
args.
- Change
method
--> agg_method
, and use method
to pass to map_orthologs
instead.
- Pass up additional args from
map_orthologs
.
- Add link to detailed explanation of matrix aggregation/expansion
in
many2many_rows
docs.
- Automatically pick best method for many:1 or many:many mapping.
as_integers
: new arg that uses floor
.
- Rename
FUN
to agg_fun
.
- Add new data
gprofiler_namespace
. Used to validate target=
arg
in gprofiler2
functions.
- Upgraded
aggregate_mapped_genes
:
- Can now used
gene_map
made by map_orthologs
or map_genes
.
- Can now handle many:many relationships.
- Will automatically pick the best method to perform aggregation and/or
expansion.
- Removed internal function
aggregate_mapped_genes_twice
- Extracted aggregation args from
non121_strategy
and placed them in their own new own (agg_fun
) since these options are
no longer mutually exclusive due to many:many expansion/aggregation.
- Pass up
as_DelayedArray
- Bump to v1.3.0 and R >=4.2 now that we're developing on Bioc 3.16.
- Add ISSUE_TEMPLATE.
prepare_tree
:
- Add
tree_source
options: path / URL / OmaDB / UCSC / timetree
Bug fixes
map_genes
: Fix report at completion.
- Add safeguards against using aggregation when
gene_df
isn't a matrix.
- Removed
DelayedMatrixStats
Import (no longer needed).
- Fix all unit tests and examples after making all updates.
- Recognize sparse/dense matrix or delayedarray in
check_agg_args
.
orthogene 1.2.1
Bug fixes
- Make
test-map_orthologs_babelgene
less stringent
with the number of expected genes.
orthogene 1.2.0
Bug fixes
- Increment to v2.0 now that Bioc 3.15 is the RELEASE.
orthogene 1.1.5
Bug fixes
map_orthologs_babelgene
- Add "Bad credentials" check for
piggyback
.
- Add
use_old
as an optional arg so I can switch to more recent versions
of babelgene::orthologs_df
if need be.
- Use updated built-in
babelgene::orthologs_df
by default.
- Throw error if trying to map between two non-human species.
- Filter support==NA mappings by default, not but support>=2
like
babelgene
does by default (even when babelgene::orthologs(min_support = 1)
).
- See here for discussion of discrepancies with babelgene maintainer: https://github.com/igordot/babelgene/issues/2
New features
- Removed
aggregate_rows_delayedarray
as it wasn't being used and was far less efficient than the other methods anyway (which are also compatible with DelayedArray matrices anyway). * New unit tests:
load_data
aggregate_mapped_genes(method='stat')
sparsity
infer_species
orthogene 1.1.4
Bug fixes
- Remove
source_all
as it included a library
call.
orthogene 1.1.3
New features
Bug fixes
- Fix failing benchmarking tests.
orthogene 1.1.2
Bug fixes
convert_orthologs(method="babelgene")
now gets gene mappings
from all_genes_babelgene
instead babelgene::orthologs
(which doesn't seem to work very well, despite being dedicated for this purpose).
map_species
:
- Avoid running this function redundantly when nested in multiple layers of other functions.
common_species_names_dict
now return "scientific_name" by default, instead of "taxonomy_id"
- Match
map_species
method to whatever method is being used in the function it's wrapped within, to avoid dropping species due to naming differences.
- Add "id" column (e.g. "celegans") to all org databases to enhance their searchability.
- Add
map_species_check_args
.
- Ensure proper method-specific
output_format
when passing species to other functions.
New features
plot_orthotree
: Automated plotting of phylogenetic trees with 1:1 ortholog report annotations. Includes several subfunctions:
prepare_tree
(exported): Read, prune and standardise a phylogenetic tree.
gather_images
(internal): More robust way to find and import valid phylopic silhouettes. Will make PR requests to rphylopic
and ggimage
/ggtree
to include this functionality.
- Added unit tests for
report_orthologs
, especially when method="babelgene"
.
- GitHub Actions:
- Merge both GHA workflows into one, as implemented in
templateR
.
- Added citation info to README.
- Save
all_genes_babelgene
ortholog data to orthogene-specific cache instead of tempdir to avoid re-downloading every R session.
orthogene 1.1.1
Bug fixes
- Made GHA less dependent on hard-coded R/bioc versions.
orthogene 1.1.0
New features
orthogene 0.99.9
New features
- Replaced R-CMD GHA with bioc-check GHA.
- Added new badges.
Bug fixes
- Adjusted vignette yamls to make resulting htmls smaller.
orthogene 0.99.8
New features
orthogene
now supports DelayedArray
objects as gene_df
input.
create_background
now uses all_genes
when all 3 species are the same.
orthogene 0.99.7
New features
- Added new function
create_background
.
- Added new function
infer_species
.
report_orthologs
and convert_orthologs
can now handle cases where
input_species
is the same as output_species
.
- Add internal function
get_all_orgs
to easily list all organisms from
different packages.
- Added
all_genes
method "babelgene".
Bug fixes
report_orthologs
no longer throws error due to not finding tar_genes
.
orthogene 0.99.6
Bug fixes
- Allow all messages to be suppressed in
report_orthologs
.
orthogene 0.99.3
New features
- License switched to GPL-3 (to be compliant with Bioc).
- New method "babelgene" added to
convert_orthologs
.
orthogene 0.99.2
New features
- License switched to GPL3 (>=3).
Bug fixes
GenomeInfoDbData
now required.
orthogene 0.1.0
New features
orthogene
released to Bioconductor.