Package: npGSEA Type: Package Title: Permutation approximation methods for gene set enrichment analysis (non-permutation GSEA) Version: 1.49.0 Date: 2015-5-6 Author: Jessica Larson and Art Owen Maintainer: Jessica Larson Imports: Biobase, methods, BiocGenerics, graphics, stats Suggests: ALL, genefilter, limma, hgu95av2.db, ReportingTools, BiocStyle Depends: GSEABase (>= 1.24.0) Description: Current gene set enrichment methods rely upon permutations for inference. These approaches are computationally expensive and have minimum achievable p-values based on the number of permutations, not on the actual observed statistics. We have derived three parametric approximations to the permutation distributions of two gene set enrichment test statistics. We are able to reduce the computational burden and granularity issues of permutation testing with our method, which is implemented in this package. npGSEA calculates gene set enrichment statistics and p-values without the computational cost of permutations. It is applicable in settings where one or many gene sets are of interest. There are also built-in plotting functions to help users visualize results. License: Artistic-2.0 biocViews: GeneSetEnrichment, Microarray, StatisticalMethod, Pathways Collate: 'getIncidence.R' 'miscFunctions.R' 'miscDataPrepFunctions.R' 'npGSEA.R' 'AllClasses.R' 'AllGenerics.R' 'npGSEAResultBeta-accessors.R' 'npGSEAResultChiSq-accessors.R' 'npGSEAResultNorm-accessors.R' 'npGSEAPlot-methods.R' 'show-methods.R' 'pValues-methods.R' Packaged: 2026-07-03 19:59:04 UTC; root Config/pak/sysreqs: libpng-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:39:01 UTC RemoteUrl: https://github.com/bioc/npGSEA RemoteRef: HEAD RemoteSha: ec632c00f1f4f2f5db5f391ff6f42810e0f20b1c NeedsCompilation: no