Package: normr
Type: Package
Title: Normalization and difference calling in ChIP-seq data
Version: 1.39.2
Date: 2026-05-21
Authors@R: c(person(given="Johannes",family="Helmuth",
        email="johannes.helmuth@laborberlin.com", role=c("aut", "cre")),
        person(given="Ho-Ryun",family="Chung",
        email="chung@molgen.mpg.de", role=c("aut")))
Author: Johannes Helmuth [aut, cre], Ho-Ryun Chung [aut]
Maintainer: Johannes Helmuth <johannes.helmuth@laborberlin.com>
Description: Robust normalization and difference calling procedures for
        ChIP-seq and alike data. Read counts are modeled jointly as a
        binomial mixture model with a user-specified number of
        components. A fitted background estimate accounts for the
        effect of enrichment in certain regions and, therefore,
        represents an appropriate null hypothesis. This robust
        background is used to identify significantly enriched or
        depleted regions.
License: GPL-2
Depends: R (>= 3.3.0)
LinkingTo: Rcpp
SystemRequirements: C++11
Imports: methods, stats, utils, grDevices, parallel, GenomeInfoDb,
        GenomicRanges, IRanges, Rcpp (>= 0.11), qvalue (>= 2.2),
        bamsignals (>= 1.4), rtracklayer (>= 1.32)
Suggests: BiocStyle, testthat (>= 1.0), knitr, rmarkdown
Enhances: BiocParallel
biocViews: Bayesian, DifferentialPeakCalling, Classification,
        DataImport, ChIPSeq, RIPSeq, FunctionalGenomics, Genetics,
        MultipleComparison, Normalization, PeakDetection,
        Preprocessing, Alignment
VignetteBuilder: knitr
NeedsCompilation: yes
Collate: 'NormRFit.R' 'methods.R' 'NormRCountConfig.R' 'RcppExports.R'
RoxygenNote: 6.0.1
URL: https://github.com/your-highness/normR
BugReports: https://github.com/your-highness/normR/issues
Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libxml2-dev
        libssl-dev xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-05-21 16:15:38 UTC
RemoteUrl: https://github.com/bioc/normr
RemoteRef: HEAD
RemoteSha: f2ac4d8bc9852d6395708dc7cd0636ab1fba1483
Packaged: 2026-07-03 05:26:08 UTC; root