Package: netZooR Type: Package Title: A menagerie of methods for the inference and analysis of gene regulatory networks Version: 1.17.0 Date: 2025-07-31 Authors@R: c(person("Tara", "Eicher", email = "teicher@hsph.harvard.edu", role = c("aut"), comment = c(ORCID = "0000-0003-1809-4458")), person("Marouen", "Ben Guebila", email = "marouen.b.guebila@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0001-5934-966X")), person("Tian", "Wang", email = "tian.wang@bc.edu", role = c("aut"), comment = c(ORCID = "0000-0002-2767-3243")), person("John", "Platig", email="john.platig@channing.harvard.edu", role="aut"), person("Marieke", "Kuijjer", email = "marieke.kuijjer@ncmm.uio.no", role = "aut", comment = c(ORCID = "0000-0001-6280-3130")), person("Megha", "Padi", email = "mpadi@email.arizona.edu", role = "aut", comment = c(ORCID = "0000-0002-3446-4562")), person("Rebekka", "Burkholz", email = "rburkholz@hsph.harvard.edu",role = "aut"), person("Des", "Weighill", email = "",role = "aut", comment = c(ORCID = "0000-0003-4979-5871")), person("Chen", "Chen", email = "",role = "aut", comment = c(ORCID = "0000-0002-8042-7201")), person("Kate", "Shutta", email = "",role = "aut", comment = c(ORCID = "0000-0003-0402-3771"))) Description: netZooR unifies the implementations of several Network Zoo methods (netzoo, netzoo.github.io) into a single package by creating interfaces between network inference and network analysis methods. Currently, the package has 3 methods for network inference including PANDA and its optimized implementation OTTER (network reconstruction using mutliple lines of biological evidence), LIONESS (single-sample network inference), and EGRET (genotype-specific networks). Network analysis methods include CONDOR (community detection), ALPACA (differential community detection), CRANE (significance estimation of differential modules), MONSTER (estimation of network transition states). In addition, YARN allows to process gene expresssion data for tissue-specific analyses and SAMBAR infers missing mutation data based on pathway information. Depends: R (>= 4.2.0), igraph, reticulate, pandaR, Biobase, Remotes: stan-dev/cmdstanr, jnpaulson/pandaR, cytoscape/RCy3 biocViews: GeneExpression, GeneRegulation, GraphAndNetwork, Microarray, Network, NetworkInference, Transcription Imports: cmdstanr, AnnotationDbi, assertthat, biomaRt, cmdstanr, corpcor, data.table, doParallel, downloader, dplyr, edgeR, foreach, GeneNet, ggdendro, ggplot2, GO.db, GOstats, gplots, graphics, grid, limma, loo, MASS, Matrix, matrixcalc, matrixStats, matrixTests, methods, nnet, org.Hs.eg.db, parallel, penalized, preprocessCore, quantro, rARPACK, RColorBrewer, RCy3, readr, reshape, reshape2, stats, STRINGdb, tidyr, utils, vegan, viridisLite, License: GPL-3 Encoding: UTF-8 LazyData: false Suggests: dorothea, knitr, pkgdown, rmarkdown, testthat (>= 2.1.0), Additional_repositories: https://stan-dev.r-universe.dev VignetteEngine: knitr VignetteBuilder: knitr RoxygenNote: 7.3.2 BugReports: https://github.com/netZoo/netZooR/issues URL: https://github.com/netZoo/netZooR, https://netzoo.github.io/ PackageStatus: Deprecated Config/pak/sysreqs: cmake libglpk-dev make libbz2-dev libicu-dev liblzma-dev libpng-dev libuv1-dev libxml2-dev libssl-dev python3 libx11-dev xz-utils libzmq3-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 13:06:30 UTC RemoteUrl: https://github.com/bioc/netZooR RemoteRef: HEAD RemoteSha: ad27b19fcdded0383d464ae8fa8c00c0c94c402a NeedsCompilation: no Packaged: 2026-10-06 11:35:40 UTC; root Author: Tara Eicher [aut] (ORCID: ), Marouen Ben Guebila [aut, cre] (ORCID: ), Tian Wang [aut] (ORCID: ), John Platig [aut], Marieke Kuijjer [aut] (ORCID: ), Megha Padi [aut] (ORCID: ), Rebekka Burkholz [aut], Des Weighill [aut] (ORCID: ), Chen Chen [aut] (ORCID: ), Kate Shutta [aut] (ORCID: ) Maintainer: Marouen Ben Guebila