Package 'muscData'

Title: Multi-sample multi-group scRNA-seq data
Description: Data package containing a collection of multi-sample multi-group scRNA-seq datasets in SingleCellExperiment Bioconductor object format.
Authors: Helena L. Crowell [aut, cre]
Maintainer: Helena L. Crowell <[email protected]>
License: MIT + file LICENSE
Version: 1.27.1
Built: 2026-10-10 10:42:25 UTC
Source: https://github.com/bioc/muscData

Help Index

Kang18_8vs8 dataset

Description

  • 10x droplet-based scRNA-seq PBMC data from 8 Lupus patients before and after 6h-treatment with INF-beta.

  • The dataset contains 35635 features across 29065 cells, and no filtering or preprocessing has been applied.

  • The original data is deposited in the Gene Expression Ombnibus (GEO) under accession number GSE96583.

Usage

Kang18_8vs8(metadata = FALSE)

Arguments

metadata

logical value indicating whether ExperimentHub metadata (describing the overall dataset) should be returned only, or if the whole dataset should be loaded. Defaults to FALSE.

Details

link to reference:

https://www.ncbi.nlm.nih.gov/pubmed/29227470

link to raw data:

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE96583

Value

an object of class SingleCellExperiment.

Author(s)

Helena L. Crowell [email protected]

References

Kang et al. (2019). "Multiplexed droplet single-cell RNA-sequencing using natural genetic variation", Nature Biotechnology 36, 89-94.

Examples

# load metadata only
Kang18_8vs8(metadata = TRUE)

# load SingleCellExperiment
Kang18_8vs8(metadata = FALSE)