Changes in version 1.13.0 (2022-04-21) o Match NEWS and DESCRIPTION versioning Changes in version 1.12.0 (2020-11-23) o Update selection of significant results in the 'topDirs' function. Major change, results will be more strict compared to pre-2.0.0 version o Removed 'BLMA' and 'metap' dependency, added 'aggregation' dependency o P-values are aggregated using 'max' by default. I.e., for a region differentially interacting with multiple regions, a maximum p-value will be selected. Fisher, Lancaster, and Sidak methods are also available o Harmonize counting of significant regions using 'p.adj_cutoff' only ('alpha' cutoff removed) o The 'manhattan' function is harmonized with 'topDirs' o The 'perm_test' function is harmonized with 'topDirs' o Update vignettes to match functions Changes in version 1.7.1 (2020-08-28) o Track NEWS o Bump version o Update R version dependency from 3.5.0 to 4.0 o Add exported objects to NAMESPACE that caused BiocCheck error o Add CITATION, also to README.md file o Update DESCRIPTION o Add Mikhail Dozmorov as Maintainer o Add URL and BugReports fields