{"GO.ID":"GO:0002250","Term":"adaptive immune response","Annotated":374,"Significant":99,"Expected":22.59,"Rank in p.value_classic":6,"p.value_elim":7.8e-20,"genes":"ASCL2,B2M,BCL6,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD274,CD28,CD40,CD7,CD74,CD80,CEACAM1,CLEC10A,CLEC6A,CR1L,CSF2RB,CTLA4,CTSL,CTSS,CX3CR1,ERAP2,EXO1,FGL1,GPR183,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL18BP,IL27,IL4I1,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KLRK1,LAG3,LAMP3,LILRA1,LILRB3,LTA,LYN,MCOLN2,NOD2,P2RX7,PARP3,PDCD1,PDCD1LG2,RELB,RIPK2,RNF19B,RSAD2,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF7,SLC11A1,TAP1,TAP2,TBX21,TLR8,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,UNG,ZC3H12A"} {"GO.ID":"GO:0002503","Term":"peptide antigen assembly with MHC class II protein complex","Annotated":13,"Significant":13,"Expected":0.79,"Rank in p.value_classic":37,"p.value_elim":1.3e-16,"p.value_classic":1.3e-16,"genes":"B2M,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"GO.ID":"GO:0019886","Term":"antigen processing and presentation of exogenous peptide antigen via MHC class II","Annotated":27,"Significant":16,"Expected":1.63,"Rank in p.value_classic":69,"p.value_elim":1.8e-13,"p.value_classic":1.9e-13,"genes":"B2M,CD74,CTSL,CTSS,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"GO.ID":"GO:0051607","Term":"defense response to virus","Annotated":262,"Significant":51,"Expected":15.82,"Rank in p.value_classic":63,"p.value_elim":9.1e-11,"p.value_classic":5.8e-14,"genes":"ACOD1,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,CXCL10,CXCL9,DDX60,DTX3L,FGL2,GBP1,GBP2,GBP3,GBP5,GBP7,IFI27,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12RB1,IL15,IL27,IRF1,IRF7,ISG20,NLRC5,OAS2,OAS3,PARP9,PLSCR1,PMAIP1,PML,RSAD2,RTP4,SERINC5,STAT1,STAT2,TANK,TLR7,TLR8,TRIM22,TRIM31,TSPAN32,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0001916","Term":"positive regulation of T cell mediated cytotoxicity","Annotated":33,"Significant":15,"Expected":1.99,"Rank in p.value_classic":110,"p.value_elim":1.6e-10,"p.value_classic":1.7e-10,"genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,P2RX7,TAP2"} {"GO.ID":"GO:0045087","Term":"innate immune response","Annotated":733,"Significant":131,"Expected":44.27,"Rank in p.value_classic":12,"p.value_elim":6.1e-10,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD74,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CSF1,CTSS,CX3CR1,CXCL10,CYLD,DDX60,DTX3L,EDN1,FCN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GRAMD4,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-E,HLA-F,HLA-G,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL27,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,PARP14,PARP9,PLSCR1,PML,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RSAD2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAT1,STAT2,TANK,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF14,TRAFD1,TRIM22,TRIM31,TYRO3,UBD,UBE2L6,ZBP1,ZNFX1"} {"GO.ID":"GO:0034341","Term":"response to type II interferon","Annotated":121,"Significant":35,"Expected":7.31,"Rank in p.value_classic":51,"p.value_elim":1.3e-09,"p.value_classic":2.3e-15,"genes":"ACOD1,CALCOCO2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,CIITA,EDN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,HLA-DPA1,IFITM1,IFITM2,IFITM3,IL12RB1,IRF1,JAK2,MEFV,NLRC5,NUB1,PARP14,PARP9,RAB20,SLC11A1,STAT1,UBD"} {"GO.ID":"GO:0032729","Term":"positive regulation of type II interferon production","Annotated":66,"Significant":19,"Expected":3.99,"Rank in p.value_classic":145,"p.value_elim":6.2e-09,"p.value_classic":6.5e-09,"genes":"BTN3A1,BTN3A2,HLA-A,HLA-DPA1,HLA-DPB1,IL12A,IL12RB1,IL12RB2,IL27,JAK2,KLRK1,LTA,PDE4B,RIPK2,SLAMF1,SLAMF6,SLC11A1,TLR7,TLR8"} {"GO.ID":"GO:0006954","Term":"inflammatory response","Annotated":677,"Significant":95,"Expected":40.89,"Rank in p.value_classic":55,"p.value_elim":1e-08,"p.value_classic":4.3e-15,"genes":"ACOD1,ADAM8,ADGRE5,ADORA3,AGR2,AGT,AIM2,AOC3,APOL2,APOL3,APPL2,BCL6,C3,C4A,C4B,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD163,CD28,CD40,CDH5,CRHBP,CSF1,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,GBP2,GBP5,GGT5,GHRL,GPR31,GSDMD,HGF,HLA-DRB1,HLA-E,IDO1,IFI35,IL15,IL1RN,IL22RA2,IL27,IL31RA,JAK2,KARS1,KLF4,LPL,LRRK2,LTA,LY75,LYN,MEFV,MMP25,MMP9,NCF1,NLRP12,NMI,NOD2,OSM,P2RX7,PLSCR1,POLB,PROK2,PTGER4,RELB,RIPK2,SBNO2,SLAMF1,SLAMF8,SLC11A1,STAP1,SUCNR1,TICAM2,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TRIM31,TYRO3,VCAM1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0071222","Term":"cellular response to lipopolysaccharide","Annotated":182,"Significant":33,"Expected":10.99,"Rank in p.value_classic":151,"p.value_elim":1e-08,"p.value_classic":1.1e-08,"genes":"ACOD1,CARD16,CASP7,CD274,CD40,CD80,CMPK2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,GBP2,GBP3,GBP5,JAK2,KLRK1,LILRA2,LITAF,LYN,MMP9,NOD2,PDCD1LG2,PDE4B,PLSCR4,PPM1E,RIPK2,SBNO2,SCIMP,STAP1,TICAM2,TIFAB,ZC3H12A"} {"GO.ID":"GO:0050830","Term":"defense response to Gram-positive bacterium","Annotated":60,"Significant":17,"Expected":3.62,"Rank in p.value_classic":172,"p.value_elim":5.1e-08,"p.value_classic":5.3e-08,"genes":"CASP4,GBP2,GBP4,GBP6,GBP7,GSDMD,H2BC21,HLA-A,HLA-E,IL12A,KLRK1,LTA,NOD2,P2RX7,RIPK2,TNFRSF14,TNFSF8"} {"GO.ID":"GO:0045071","Term":"negative regulation of viral genome replication","Annotated":52,"Significant":15,"Expected":3.14,"Rank in p.value_classic":203,"p.value_elim":2.4e-07,"p.value_classic":2.5e-07,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,OAS2,OAS3,PLSCR1,RSAD2,ZNFX1"} {"GO.ID":"GO:0006958","Term":"complement activation, classical pathway","Annotated":23,"Significant":10,"Expected":1.39,"Rank in p.value_classic":208,"p.value_elim":3.3e-07,"p.value_classic":3.4e-07,"genes":"C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CR1L,SERPING1"} {"GO.ID":"GO:0070269","Term":"pyroptosis","Annotated":30,"Significant":11,"Expected":1.81,"Rank in p.value_classic":219,"p.value_elim":6.7e-07,"p.value_classic":6.9e-07,"genes":"AIM2,CASP4,GBP1,GBP2,GBP3,GBP5,GSDMA,GSDMD,IFI27,MEFV,ZBP1"} {"GO.ID":"GO:0000727","Term":"double-strand break repair via break-induced replication","Annotated":11,"Significant":7,"Expected":0.66,"Rank in p.value_classic":222,"p.value_elim":7.5e-07,"p.value_classic":7.6e-07,"genes":"CDC45,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7"} {"GO.ID":"GO:0050778","Term":"positive regulation of immune response","Annotated":598,"Significant":115,"Expected":36.12,"Rank in p.value_classic":13,"p.value_elim":7.9e-07,"p.value_classic":4.8e-30,"genes":"ACOD1,ADAM8,AIM2,APPL2,AURKB,B2M,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD74,CD80,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CTLA4,CTSS,CYLD,DDX60,FCN1,FYB1,GBP1,GBP2,GBP5,GPR31,GRAMD4,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KLRK1,LAG3,LILRA2,LTA,LYN,MEFV,NLRC5,NMI,NOD2,NR4A3,OAS3,P2RX7,PARP9,PDE4B,PLPP4,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLC11A1,STAP1,TAP2,TBX21,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF21,TNFSF13B,TRIM31,TYRO3,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0071346","Term":"cellular response to type II interferon","Annotated":102,"Significant":24,"Expected":6.16,"Rank in p.value_classic":144,"p.value_elim":1e-06,"p.value_classic":6e-09,"genes":"ACOD1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,EDN1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,HLA-DPA1,IL12RB1,IRF1,JAK2,NLRC5,PARP14,PARP9,RAB20,STAT1"} {"GO.ID":"GO:0070098","Term":"chemokine-mediated signaling pathway","Annotated":65,"Significant":16,"Expected":3.93,"Rank in p.value_classic":226,"p.value_elim":1e-06,"p.value_classic":1.1e-06,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,LYN,PADI2"} {"GO.ID":"GO:0006959","Term":"humoral immune response","Annotated":134,"Significant":35,"Expected":8.09,"Rank in p.value_classic":64,"p.value_elim":1.2e-06,"p.value_classic":7e-14,"genes":"ACOD1,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL13,CD28,CD83,CFB,CFH,CR1L,CXCL10,CXCL11,CXCL5,CXCL9,EXO1,FCN1,GPR183,H2BC21,HLA-A,HLA-DQB1,HLA-DRB1,HLA-E,IL7,LTA,NOD2,PDCD1,PSMB10,SERPING1,SLC11A1,TNFRSF21"} {"GO.ID":"GO:0006268","Term":"DNA unwinding involved in DNA replication","Annotated":21,"Significant":9,"Expected":1.27,"Rank in p.value_classic":239,"p.value_elim":1.5e-06,"p.value_classic":1.6e-06,"genes":"CDC45,GINS1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RECQL4"} {"GO.ID":"GO:0070234","Term":"positive regulation of T cell apoptotic process","Annotated":12,"Significant":7,"Expected":0.72,"Rank in p.value_classic":242,"p.value_elim":1.7e-06,"p.value_classic":1.7e-06,"genes":"ADAM8,BCL2L11,CCL5,CD274,IDO1,P2RX7,PDCD1"} {"GO.ID":"GO:0042832","Term":"defense response to protozoan","Annotated":22,"Significant":9,"Expected":1.33,"Rank in p.value_classic":251,"p.value_elim":2.4e-06,"p.value_classic":2.5e-06,"genes":"BATF2,GBP1,GBP2,GBP4,GBP6,GBP7,IRF4,SLC11A1,TSPAN32"} {"GO.ID":"GO:0002476","Term":"antigen processing and presentation of endogenous peptide antigen via MHC class Ib","Annotated":13,"Significant":7,"Expected":0.79,"Rank in p.value_classic":262,"p.value_elim":3.5e-06,"p.value_classic":3.6e-06,"genes":"HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP2"} {"GO.ID":"GO:0071356","Term":"cellular response to tumor necrosis factor","Annotated":201,"Significant":32,"Expected":12.14,"Rank in p.value_classic":211,"p.value_elim":6e-06,"p.value_classic":4.2e-07,"genes":"ACOD1,AIM2,BRCA1,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CRHBP,CX3CR1,CYLD,EDN1,FAS,GBP1,GBP2,GBP3,IL18BP,JAK2,PID1,STAT1,TANK,TIFA,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,ZC3H12A"} {"GO.ID":"GO:0030174","Term":"regulation of DNA-templated DNA replication initiation","Annotated":14,"Significant":7,"Expected":0.85,"Rank in p.value_classic":277,"p.value_elim":6.6e-06,"p.value_classic":6.7e-06,"genes":"CDT1,MCM2,MCM4,MCM5,MCM6,MCM7,TICRR"} {"GO.ID":"GO:2000425","Term":"regulation of apoptotic cell clearance","Annotated":10,"Significant":6,"Expected":0.6,"Rank in p.value_classic":280,"p.value_elim":8e-06,"p.value_classic":8.1e-06,"genes":"C2,C3,C4A,C4B,CD300LF,TGM2"} {"GO.ID":"GO:0001961","Term":"positive regulation of cytokine-mediated signaling pathway","Annotated":54,"Significant":13,"Expected":3.26,"Rank in p.value_classic":298,"p.value_elim":0.00001,"p.value_classic":0.00001,"genes":"CASP4,CD300LF,CD74,CSF1,EDN1,IL7,IRF7,NLRC5,PARP14,PARP9,RIPK2,TICAM2,ZBP1"} {"GO.ID":"GO:0042130","Term":"negative regulation of T cell proliferation","Annotated":54,"Significant":13,"Expected":3.26,"Rank in p.value_classic":299,"p.value_elim":0.00001,"p.value_classic":0.00001,"genes":"BTN2A2,CD274,CD80,CTLA4,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,PDCD1LG2,TNFRSF14,TNFRSF21,TSPAN32"} {"GO.ID":"GO:0030593","Term":"neutrophil chemotaxis","Annotated":87,"Significant":17,"Expected":5.25,"Rank in p.value_classic":302,"p.value_elim":0.00001,"p.value_classic":0.00001,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,NOD2,PDE4B,TNFAIP6"} {"GO.ID":"GO:0019885","Term":"antigen processing and presentation of endogenous peptide antigen via MHC class I","Annotated":19,"Significant":11,"Expected":1.15,"Rank in p.value_classic":132,"p.value_elim":0.00001,"p.value_classic":1.8e-09,"genes":"B2M,ERAP2,HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"GO.ID":"GO:0050729","Term":"positive regulation of inflammatory response","Annotated":127,"Significant":25,"Expected":7.67,"Rank in p.value_classic":187,"p.value_elim":0.00002,"p.value_classic":1.3e-07,"genes":"ADAM8,AGT,AIM2,C3,CASP4,CD28,GSDMD,HLA-E,IDO1,IFI35,IL15,KARS1,LPL,LRRK2,LTA,MEFV,NLRP12,NMI,OSM,PTGER4,STAP1,SUCNR1,TLR7,TNFRSF11A,ZBP1"} {"GO.ID":"GO:0050766","Term":"positive regulation of phagocytosis","Annotated":55,"Significant":13,"Expected":3.32,"Rank in p.value_classic":308,"p.value_elim":0.00002,"p.value_classic":0.00002,"genes":"APPL2,C2,C3,C4A,C4B,CD300LF,FCN1,IL15,IL15RA,MERTK,NOD2,SLC11A1,STAP1"} {"GO.ID":"GO:0002486","Term":"antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent","Annotated":12,"Significant":6,"Expected":0.72,"Rank in p.value_classic":324,"p.value_elim":0.00003,"p.value_classic":0.00003,"genes":"HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G"} {"GO.ID":"GO:1902969","Term":"mitotic DNA replication","Annotated":17,"Significant":7,"Expected":1.03,"Rank in p.value_classic":325,"p.value_elim":0.00003,"p.value_classic":0.00003,"genes":"BCL6,CDC45,GINS1,MCM2,MCM4,MCM6,TK1"} {"GO.ID":"GO:0050852","Term":"T cell receptor signaling pathway","Annotated":111,"Significant":19,"Expected":6.7,"Rank in p.value_classic":327,"p.value_elim":0.00003,"p.value_classic":0.00003,"genes":"BTN2A2,BTN3A1,BTN3A2,BTN3A3,CD28,CEACAM1,CTLA4,CYLD,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,ITK,PDE4B,RIPK2,TNFRSF21,ZC3H12A"} {"GO.ID":"GO:0002230","Term":"positive regulation of defense response to virus by host","Annotated":29,"Significant":9,"Expected":1.75,"Rank in p.value_classic":328,"p.value_elim":0.00003,"p.value_classic":0.00003,"genes":"AIM2,APOBEC3G,DTX3L,IL12RB1,IL27,PARP9,STAT1,TRIM22,ZC3H12A"} {"GO.ID":"GO:0042531","Term":"positive regulation of tyrosine phosphorylation of STAT protein","Annotated":43,"Significant":11,"Expected":2.6,"Rank in p.value_classic":329,"p.value_elim":0.00003,"p.value_classic":0.00003,"genes":"CCL5,CD40,IL12A,IL15,IL31RA,JAK2,LYN,OSM,PARP14,PARP9,TNFSF18"} {"GO.ID":"GO:0002710","Term":"negative regulation of T cell mediated immunity","Annotated":24,"Significant":8,"Expected":1.45,"Rank in p.value_classic":339,"p.value_elim":0.00005,"p.value_classic":0.00005,"genes":"CD80,CEACAM1,HLA-F,HLA-G,IL4I1,NOD2,SLAMF1,TBX21"} {"GO.ID":"GO:0071347","Term":"cellular response to interleukin-1","Annotated":88,"Significant":16,"Expected":5.31,"Rank in p.value_classic":346,"p.value_elim":0.00006,"p.value_classic":0.00006,"genes":"ACOD1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,EDN1,GBP1,GBP2,GBP3,IL1RN,TANK,VRK2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0006955","Term":"immune response","Annotated":1326,"Significant":230,"Expected":80.08,"Rank in p.value_classic":1,"p.value_elim":0.00006,"genes":"ACOD1,ADAM8,ADGRE5,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,ASCL2,AURKB,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CR1L,CSF1,CSF2RB,CTLA4,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DDX60,DLL1,DTX3L,DYSF,EDA,EDN1,ENPP2,ERAP2,EXO1,FAS,FCN1,FGL1,FGL2,FYB1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR183,GPR31,GRAMD4,GSDMD,GTPBP1,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,ICAM1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IGSF6,IL12A,IL12RB1,IL15,IL18BP,IL1RN,IL27,IL31RA,IL32,IL4I1,IL7,IRF1,IRF4,IRF7,ISG20,ITK,JAK2,JAK3,KARS1,KLRK1,LAG3,LAMP3,LILRA1,LILRA2,LILRB3,LITAF,LTA,LY75,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NR4A3,NUB1,OAS2,OAS3,OPTN,OSM,P2RX7,PARP14,PARP3,PARP9,PDCD1,PDCD1LG2,PDE4B,PLPP4,PLSCR1,PML,PSMB10,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RSAD2,S100A13,SBNO2,SCIMP,SECTM1,SERINC5,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,STAT1,STAT2,SUCNR1,TANK,TAP1,TAP2,TBX21,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TRAFD1,TRIM22,TRIM31,TYRO3,UBD,UBE2L6,UNG,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0032731","Term":"positive regulation of interleukin-1 beta production","Annotated":54,"Significant":12,"Expected":3.26,"Rank in p.value_classic":350,"p.value_elim":0.00007,"p.value_classic":0.00007,"genes":"AIM2,GBP5,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,RIPK2,TLR8"} {"GO.ID":"GO:0046718","Term":"symbiont entry into host cell","Annotated":129,"Significant":24,"Expected":7.79,"Rank in p.value_classic":217,"p.value_elim":0.00009,"p.value_classic":6.8e-07,"genes":"CD74,CD80,CDK1,CIITA,CTSL,CXADR,DYNLT1,FCN1,HAVCR1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,ITGB5,NRP1,PLSCR1,SLAMF1,TNFRSF14,TPCN1,TRIM22,TRIM31,TYRO3,WWP1"} {"GO.ID":"GO:0032496","Term":"response to lipopolysaccharide","Annotated":275,"Significant":49,"Expected":16.61,"Rank in p.value_classic":86,"p.value_elim":0.00009,"p.value_classic":5.7e-12,"genes":"ACOD1,C2,CARD16,CASP7,CD274,CD40,CD80,CMPK2,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,GBP2,GBP3,GBP5,GCH1,IDO1,IL12A,IL12RB2,IL18BP,JAK2,KLRK1,LILRA2,LITAF,LTA,LYN,MMP9,NOD2,P2RX7,PDCD1LG2,PDE4B,PLSCR4,PPM1E,PTGER4,RIPK2,SBNO2,SCIMP,SLC11A1,STAP1,THBD,TICAM2,TIFAB,TNFRSF11A,VCAM1,ZC3H12A"} {"GO.ID":"GO:0042102","Term":"positive regulation of T cell proliferation","Annotated":86,"Significant":18,"Expected":5.19,"Rank in p.value_classic":256,"p.value_elim":0.00011,"p.value_classic":2.9e-06,"genes":"CCL5,CD274,CD28,CD80,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12RB1,IL15,JAK2,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"GO.ID":"GO:0045591","Term":"positive regulation of regulatory T cell differentiation","Annotated":20,"Significant":7,"Expected":1.21,"Rank in p.value_classic":365,"p.value_elim":0.00011,"p.value_classic":0.00011,"genes":"BCL6,BTN2A2,HLA-DRA,HLA-DRB1,HLA-G,IL4I1,SOCS1"} {"GO.ID":"GO:0048247","Term":"lymphocyte chemotaxis","Annotated":47,"Significant":13,"Expected":2.84,"Rank in p.value_classic":255,"p.value_elim":0.00013,"p.value_classic":2.7e-06,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CXCL10,CXCL11,GPR183,HSD3B7,KLRK1,PADI2"} {"GO.ID":"GO:0060337","Term":"type I interferon-mediated signaling pathway","Annotated":66,"Significant":13,"Expected":3.99,"Rank in p.value_classic":371,"p.value_elim":0.00013,"p.value_classic":0.00013,"genes":"IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IRF7,NLRC5,OAS2,OAS3,STAT1,STAT2,TANK,ZBP1"} {"GO.ID":"GO:0002720","Term":"positive regulation of cytokine production involved in immune response","Annotated":74,"Significant":17,"Expected":4.47,"Rank in p.value_classic":236,"p.value_elim":0.00014,"p.value_classic":1.4e-06,"genes":"B2M,CD74,HLA-A,HLA-E,HLA-F,HLA-G,NOD2,NR4A3,P2RX7,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:0002224","Term":"toll-like receptor signaling pathway","Annotated":67,"Significant":13,"Expected":4.05,"Rank in p.value_classic":382,"p.value_elim":0.00015,"p.value_classic":0.00016,"genes":"CD274,CD300LF,CTSS,IRF1,IRF4,IRF7,SCIMP,TICAM2,TLR10,TLR5,TLR7,TLR8,TYRO3"} {"GO.ID":"GO:0043380","Term":"regulation of memory T cell differentiation","Annotated":10,"Significant":5,"Expected":0.6,"Rank in p.value_classic":379,"p.value_elim":0.00015,"p.value_classic":0.00015,"genes":"BCL6,FGL2,HLA-DRA,HLA-DRB1,IL12RB1"} {"GO.ID":"GO:0050870","Term":"positive regulation of T cell activation","Annotated":218,"Significant":43,"Expected":13.17,"Rank in p.value_classic":83,"p.value_elim":0.00016,"p.value_classic":3.6e-12,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CYLD,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL4I1,IL7,JAK2,KITLG,KLRK1,LYN,NOD2,PDCD1LG2,RIPK2,SLAMF1,SOCS1,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:0045625","Term":"regulation of T-helper 1 cell differentiation","Annotated":11,"Significant":5,"Expected":0.66,"Rank in p.value_classic":405,"p.value_elim":0.00027,"p.value_classic":0.00027,"genes":"ASCL2,CD80,IL27,JAK3,RIPK2"} {"GO.ID":"GO:0001818","Term":"negative regulation of cytokine production","Annotated":242,"Significant":40,"Expected":14.62,"Rank in p.value_classic":141,"p.value_elim":0.00029,"p.value_classic":5.1e-09,"genes":"ACOD1,APPL2,BANK1,BCL6,BTN2A2,CARD16,CD274,CD83,CEACAM1,CX3CR1,CYLD,DLL1,GBP1,GBP7,GHRL,HGF,HLA-DRB1,HLA-F,IDO1,IL12A,JAK3,KLF4,LAG3,MEFV,MERTK,NLRP12,NMI,NOD2,OAS3,PDCD1LG2,PML,PTGER4,RELB,SLAMF1,SLC11A1,TBX21,TLR8,TNFRSF21,XAF1,ZC3H12A"} {"GO.ID":"GO:0009617","Term":"response to bacterium","Annotated":485,"Significant":86,"Expected":29.29,"Rank in p.value_classic":20,"p.value_elim":0.00031,"p.value_classic":4.3e-20,"genes":"ACOD1,B2M,BANK1,C15orf48,C2,C3,C4B,CARD16,CASP4,CASP7,CD274,CD40,CD80,CFB,CMPK2,COLEC12,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,FAM20A,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-DRB1,HLA-E,IDO1,IL12A,IL12RB2,IL18BP,IL27,JAK2,KLRK1,LILRA2,LITAF,LPL,LTA,LYN,MMP9,NLRC5,NOD2,OAS2,OAS3,OPTN,P2RX7,PDCD1LG2,PDE4B,PLAAT3,PLSCR4,PPM1E,PTGER4,RIPK2,RNF213,SBNO2,SCIMP,SLAMF8,SLC11A1,STAP1,TAP2,THBD,TICAM2,TIFAB,TLR10,TMEM255A,TNFRSF11A,TNFRSF14,TNFSF8,TRDN,VCAM1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0002281","Term":"macrophage activation involved in immune response","Annotated":17,"Significant":6,"Expected":1.03,"Rank in p.value_classic":419,"p.value_elim":0.00033,"p.value_classic":0.00033,"genes":"CX3CR1,DYSF,IFI35,NMI,SBNO2,SUCNR1"} {"GO.ID":"GO:0032693","Term":"negative regulation of interleukin-10 production","Annotated":17,"Significant":6,"Expected":1.03,"Rank in p.value_classic":420,"p.value_elim":0.00033,"p.value_classic":0.00033,"genes":"CD274,DLL1,IDO1,JAK3,PDCD1LG2,TNFRSF21"} {"GO.ID":"GO:0035456","Term":"response to interferon-beta","Annotated":32,"Significant":10,"Expected":1.93,"Rank in p.value_classic":290,"p.value_elim":0.00039,"p.value_classic":0.00001,"genes":"ACOD1,AIM2,IFITM1,IFITM2,IFITM3,IRF1,PLSCR1,PYHIN1,STAT1,XAF1"} {"GO.ID":"GO:0050731","Term":"positive regulation of peptidyl-tyrosine phosphorylation","Annotated":127,"Significant":25,"Expected":7.67,"Rank in p.value_classic":188,"p.value_elim":0.00041,"p.value_classic":1.3e-07,"genes":"AGT,BANK1,CCL5,CD40,CD74,CD80,CLEC6A,ENPP2,HBEGF,HGF,IL12A,IL15,IL31RA,JAK2,KITLG,LYN,NCF1,NOD2,NRP1,OSM,PARP14,PARP9,RIPK2,TNFRSF14,TNFSF18"} {"GO.ID":"GO:0044771","Term":"meiotic cell cycle phase transition","Annotated":12,"Significant":5,"Expected":0.72,"Rank in p.value_classic":442,"p.value_elim":0.00043,"p.value_classic":0.00044,"genes":"CDC25A,NDC80,OVOL1,PKMYT1,ZWINT"} {"GO.ID":"GO:0002863","Term":"positive regulation of inflammatory response to antigenic stimulus","Annotated":12,"Significant":5,"Expected":0.72,"Rank in p.value_classic":443,"p.value_elim":0.00043,"p.value_classic":0.00044,"genes":"C3,CD28,HLA-E,KARS1,LTA"} {"GO.ID":"GO:0045953","Term":"negative regulation of natural killer cell mediated cytotoxicity","Annotated":18,"Significant":6,"Expected":1.09,"Rank in p.value_classic":448,"p.value_elim":0.00047,"p.value_classic":0.00047,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G"} {"GO.ID":"GO:0045824","Term":"negative regulation of innate immune response","Annotated":75,"Significant":17,"Expected":4.53,"Rank in p.value_classic":241,"p.value_elim":0.00048,"p.value_classic":1.7e-06,"genes":"ACOD1,AURKB,CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,NLRC5,NMI,OAS3,PARP14,SERPING1,SLAMF8,STAT2,TRAFD1,TYRO3"} {"GO.ID":"GO:0008283","Term":"cell population proliferation","Annotated":1577,"Significant":148,"Expected":95.24,"Rank in p.value_classic":154,"p.value_elim":0.0005,"p.value_classic":1.4e-08,"genes":"ABCB1,ADORA3,AGT,APPL2,ASCL2,ATF3,ATF5,B2M,BCL6,BIRC5,BTN2A2,BTN3A1,CCL5,CCL8,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CEACAM1,CHRD,COMP,CSF1,CSF2RB,CTLA4,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYSLTR1,DAB2,DLL1,E2F1,E2F8,EDN1,FGL1,FLT3LG,GAREM1,GHRL,GINS1,GLUL,GNG2,GPR183,HAPLN3,HBEGF,HELLS,HGF,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,JAK2,KITLG,KLF4,LBH,LRP5,LRRK2,LTA,LYN,MARCKSL1,MCM10,MCM7,MIR503,MMP9,MTSS1,NCAPG2,NDC80,NMI,NOD2,NPR1,NR4A3,NRP1,OCA2,OSM,OVOL1,P2RX7,PARP10,PDCD1LG2,PID1,PIM1,PLAAT4,PLCD3,PML,PRC1,PRKX,PROK2,PSMB10,PTPRU,RAPGEF2,RASGRF1,RIPK2,S100A13,S1PR1,SCIN,SHCBP1,SIDT2,SLAMF1,SLC11A1,SLC20A1,SOX17,SSBP3,SSTR2,STAT1,STAT2,SYNE1,TACC2,TAL1,TESC,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,UHRF1,VCAM1,VCAN,VEGFC,WARS1,WDR62"} {"GO.ID":"GO:0032103","Term":"positive regulation of response to external stimulus","Annotated":528,"Significant":84,"Expected":31.89,"Rank in p.value_classic":36,"p.value_elim":0.0006,"p.value_classic":1.2e-16,"genes":"ACOD1,ADAM8,AGT,AIM2,APPL2,AURKB,C3,CASP4,CCL5,CCL7,CD274,CD28,CD300LF,CD74,CLEC6A,COLEC12,CSF1,CTSS,CX3CR1,CXCL10,CYLD,DDX60,EDN1,FCN1,GBP2,GBP5,GHRL,GRAMD4,GSDMD,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL15,IRF1,IRF4,IRF7,KARS1,KLRK1,LAG3,LILRA2,LPL,LRRK2,LTA,LYN,MEFV,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,OPTN,OSM,P2RX4,PARP9,PLSCR1,PTGER4,PYHIN1,RIPK2,RSAD2,S1PR1,SCARF1,SCIMP,SLAMF1,SLAMF6,STAP1,SUCNR1,THBD,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF11A,TRIM31,TYRO3,VEGFC,ZBP1,ZNFX1"} {"GO.ID":"GO:0045954","Term":"positive regulation of natural killer cell mediated cytotoxicity","Annotated":19,"Significant":6,"Expected":1.15,"Rank in p.value_classic":462,"p.value_elim":0.00065,"p.value_classic":0.00065,"genes":"HLA-E,HLA-F,IL12A,KLRK1,LAG3,SLAMF6"} {"GO.ID":"GO:0048245","Term":"eosinophil chemotaxis","Annotated":19,"Significant":6,"Expected":1.15,"Rank in p.value_classic":463,"p.value_elim":0.00065,"p.value_classic":0.00065,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8"} {"GO.ID":"GO:0046597","Term":"negative regulation of viral entry into host cell","Annotated":19,"Significant":6,"Expected":1.15,"Rank in p.value_classic":464,"p.value_elim":0.00065,"p.value_classic":0.00065,"genes":"CIITA,FCN1,IFITM1,IFITM2,IFITM3,TRIM31"} {"GO.ID":"GO:0098792","Term":"xenophagy","Annotated":13,"Significant":5,"Expected":0.79,"Rank in p.value_classic":467,"p.value_elim":0.00067,"p.value_classic":0.00068,"genes":"CALCOCO2,NOD2,OPTN,RIPK2,RNF213"} {"GO.ID":"GO:0051984","Term":"positive regulation of chromosome segregation","Annotated":26,"Significant":7,"Expected":1.57,"Rank in p.value_classic":469,"p.value_elim":0.00067,"p.value_classic":0.00068,"genes":"AURKB,BIRC5,CDC6,CDK1,NCAPG,NCAPG2,NCAPH"} {"GO.ID":"GO:1903975","Term":"regulation of glial cell migration","Annotated":20,"Significant":6,"Expected":1.21,"Rank in p.value_classic":482,"p.value_elim":0.00088,"p.value_classic":0.00089,"genes":"ATP1B2,CSF1,CX3CR1,GPR183,P2RX4,STAP1"} {"GO.ID":"GO:1904064","Term":"positive regulation of cation transmembrane transport","Annotated":100,"Significant":15,"Expected":6.04,"Rank in p.value_classic":489,"p.value_elim":0.00091,"p.value_classic":0.00094,"genes":"ANK2,ATP1B2,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ2,P2RX4,P2RX7,SRI,TESC,TRDN"} {"GO.ID":"GO:0070374","Term":"positive regulation of ERK1 and ERK2 cascade","Annotated":156,"Significant":20,"Expected":9.42,"Rank in p.value_classic":501,"p.value_elim":0.0011,"p.value_classic":0.00114,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,GAREM1,GLIPR2,GPR183,HLA-DRB1,ICAM1,NECAB2,NOD2,NRP1,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3"} {"GO.ID":"GO:0060333","Term":"type II interferon-mediated signaling pathway","Annotated":21,"Significant":6,"Expected":1.27,"Rank in p.value_classic":504,"p.value_elim":0.00116,"p.value_classic":0.00118,"genes":"IRF1,JAK2,NLRC5,PARP14,PARP9,STAT1"} {"GO.ID":"GO:0032816","Term":"positive regulation of natural killer cell activation","Annotated":21,"Significant":6,"Expected":1.27,"Rank in p.value_classic":505,"p.value_elim":0.00116,"p.value_classic":0.00118,"genes":"HLA-E,IL12A,IL15,IL15RA,JAK2,TICAM2"} {"GO.ID":"GO:1901223","Term":"negative regulation of non-canonical NF-kappaB signal transduction","Annotated":21,"Significant":6,"Expected":1.27,"Rank in p.value_classic":506,"p.value_elim":0.00116,"p.value_classic":0.00118,"genes":"CYLD,IFI35,LITAF,NLRP12,NMI,ZC3H12A"} {"GO.ID":"GO:0019221","Term":"cytokine-mediated signaling pathway","Annotated":408,"Significant":69,"Expected":24.64,"Rank in p.value_classic":53,"p.value_elim":0.00141,"p.value_classic":3.4e-15,"genes":"ACSL1,AIM2,APPL2,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300LF,CD74,CEACAM1,CSF1,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,EDN1,FAS,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,IRF1,IRF7,JAK2,JAK3,LILRA1,LILRA2,LYN,NLRC5,OAS2,OAS3,OSM,PADI2,PARP14,PARP9,RIPK2,SOCS1,STAP1,STAT1,STAT2,TANK,TICAM2,TIFA,TNFRSF11A,TNFRSF14,TNFSF13B,TNFSF18,VRK2,ZBP1"} {"GO.ID":"GO:0045623","Term":"negative regulation of T-helper cell differentiation","Annotated":15,"Significant":5,"Expected":0.91,"Rank in p.value_classic":521,"p.value_elim":0.00142,"p.value_classic":0.00143,"genes":"ASCL2,BCL6,JAK3,TBX21,ZC3H12A"} {"GO.ID":"GO:0002827","Term":"positive regulation of T-helper 1 type immune response","Annotated":15,"Significant":5,"Expected":0.91,"Rank in p.value_classic":522,"p.value_elim":0.00142,"p.value_classic":0.00143,"genes":"IL12RB1,RIPK2,SLAMF1,SLC11A1,TBX21"} {"GO.ID":"GO:0002823","Term":"negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":46,"Significant":14,"Expected":2.78,"Rank in p.value_classic":206,"p.value_elim":0.00146,"p.value_classic":3e-07,"genes":"ASCL2,BCL6,CD80,CEACAM1,CR1L,HLA-F,HLA-G,IL4I1,JAK3,NOD2,PARP3,SLAMF1,TBX21,ZC3H12A"} {"GO.ID":"GO:0032663","Term":"regulation of interleukin-2 production","Annotated":55,"Significant":10,"Expected":3.32,"Rank in p.value_classic":524,"p.value_elim":0.00147,"p.value_classic":0.00149,"genes":"CD28,CD80,CD83,GBP1,IRF4,LAG3,NOD2,PDE4B,RIPK2,TBX21"} {"GO.ID":"GO:0010758","Term":"regulation of macrophage chemotaxis","Annotated":22,"Significant":6,"Expected":1.33,"Rank in p.value_classic":528,"p.value_elim":0.00152,"p.value_classic":0.00154,"genes":"CCL5,CSF1,MTUS1,SLAMF1,SLAMF8,STAP1"} {"GO.ID":"GO:0032727","Term":"positive regulation of interferon-alpha production","Annotated":22,"Significant":6,"Expected":1.33,"Rank in p.value_classic":529,"p.value_elim":0.00152,"p.value_classic":0.00154,"genes":"IFIH1,IRF7,RIPK2,STAT1,TLR7,TLR8"} {"GO.ID":"GO:0070371","Term":"ERK1 and ERK2 cascade","Annotated":252,"Significant":34,"Expected":15.22,"Rank in p.value_classic":281,"p.value_elim":0.00155,"p.value_classic":8.6e-06,"genes":"ATF3,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,CDK1,CEACAM1,DAB2,EDN1,GAREM1,GBP1,GLIPR2,GPR183,HESX1,HLA-DRB1,ICAM1,IQGAP3,KARS1,LYN,MIR503,NECAB2,NLRP12,NOD2,NRP1,PTGER4,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3"} {"GO.ID":"GO:0002828","Term":"regulation of type 2 immune response","Annotated":30,"Significant":7,"Expected":1.81,"Rank in p.value_classic":536,"p.value_elim":0.00168,"p.value_classic":0.00171,"genes":"ASCL2,BCL6,CD74,IDO1,NOD2,RSAD2,TBX21"} {"GO.ID":"GO:0043068","Term":"positive regulation of programmed cell death","Annotated":470,"Significant":54,"Expected":28.39,"Rank in p.value_classic":264,"p.value_elim":0.00172,"p.value_classic":3.6e-06,"genes":"ADAM8,AGT,AIFM2,ATF3,BCL2A1,BCL2L11,BCL6,C3orf38,CAMK2D,CASP4,CASP7,CCL5,CD274,CD40,CTLA4,CTSL,CTSS,CYLD,E2F1,FAS,G0S2,GADD45B,GBP1,GBP2,GBP3,GBP5,GCH1,HCAR2,HLA-G,HTRA1,IDO1,IFIT2,IGF2R,IL12A,JAK2,LRRK2,LTA,LYN,MMP9,MYBL2,P2RX7,PDCD1,PMAIP1,PML,RAPGEF2,RIPK2,SCIN,SEPTIN4,TGM2,TNFSF10,TOP2A,UBD,ZBP1,ZC3H12A"} {"GO.ID":"GO:0002286","Term":"T cell activation involved in immune response","Annotated":101,"Significant":24,"Expected":6.1,"Rank in p.value_classic":137,"p.value_elim":0.00174,"p.value_classic":4.8e-09,"genes":"ASCL2,BCL6,CD1C,CD74,CD80,CEACAM1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,ICAM1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,SLC11A1,TBX21,TNFSF18,ZC3H12A"} {"GO.ID":"GO:0002501","Term":"peptide antigen assembly with MHC protein complex","Annotated":18,"Significant":16,"Expected":1.09,"Rank in p.value_classic":28,"p.value_elim":0.0019,"p.value_classic":3.7e-18,"genes":"B2M,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,TAPBP,TAPBPL"} {"GO.ID":"GO:0002478","Term":"antigen processing and presentation of exogenous peptide antigen","Annotated":37,"Significant":20,"Expected":2.23,"Rank in p.value_classic":48,"p.value_elim":0.00191,"p.value_classic":2e-15,"genes":"B2M,CD74,CTSL,CTSS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,TAP2"} {"GO.ID":"GO:0043065","Term":"positive regulation of apoptotic process","Annotated":454,"Significant":49,"Expected":27.42,"Rank in p.value_classic":340,"p.value_elim":0.00193,"p.value_classic":0.00005,"genes":"ADAM8,AGT,AIFM2,ATF3,BCL2A1,BCL2L11,BCL6,C3orf38,CAMK2D,CASP4,CASP7,CCL5,CD274,CD40,CTLA4,CTSL,CTSS,CYLD,E2F1,FAS,G0S2,GADD45B,GCH1,HCAR2,HLA-G,HTRA1,IDO1,IFIT2,IGF2R,IL12A,JAK2,LTA,LYN,MMP9,MYBL2,P2RX7,PDCD1,PMAIP1,PML,RAPGEF2,RIPK2,SCIN,SEPTIN4,TGM2,TNFSF10,TOP2A,UBD,ZBP1,ZC3H12A"} {"GO.ID":"GO:0032728","Term":"positive regulation of interferon-beta production","Annotated":39,"Significant":8,"Expected":2.36,"Rank in p.value_classic":546,"p.value_elim":0.00194,"p.value_classic":0.00197,"genes":"IFIH1,IRF1,IRF7,OAS2,OAS3,RIPK2,TLR7,TLR8"} {"GO.ID":"GO:0045589","Term":"regulation of regulatory T cell differentiation","Annotated":30,"Significant":11,"Expected":1.81,"Rank in p.value_classic":220,"p.value_elim":0.00199,"p.value_classic":6.9e-07,"genes":"BCL6,BTN2A2,CD28,CTLA4,HLA-DRA,HLA-DRB1,HLA-G,IL4I1,IRF1,LAG3,SOCS1"} {"GO.ID":"GO:0039530","Term":"MDA-5 signaling pathway","Annotated":10,"Significant":4,"Expected":0.6,"Rank in p.value_classic":551,"p.value_elim":0.00205,"p.value_classic":0.00207,"genes":"DDX60,IFIH1,IRF7,OAS3"} {"GO.ID":"GO:0033314","Term":"mitotic DNA replication checkpoint signaling","Annotated":10,"Significant":4,"Expected":0.6,"Rank in p.value_classic":552,"p.value_elim":0.00205,"p.value_classic":0.00207,"genes":"CDC6,CLSPN,ORC1,TICRR"} {"GO.ID":"GO:0051256","Term":"mitotic spindle midzone assembly","Annotated":10,"Significant":4,"Expected":0.6,"Rank in p.value_classic":553,"p.value_elim":0.00205,"p.value_classic":0.00207,"genes":"AURKB,BIRC5,KIF23,PRC1"} {"GO.ID":"GO:0002604","Term":"regulation of dendritic cell antigen processing and presentation","Annotated":10,"Significant":4,"Expected":0.6,"Rank in p.value_classic":554,"p.value_elim":0.00205,"p.value_classic":0.00207,"genes":"CD74,FGL2,NOD2,SLC11A1"} {"GO.ID":"GO:0071887","Term":"leukocyte apoptotic process","Annotated":106,"Significant":24,"Expected":6.4,"Rank in p.value_classic":152,"p.value_elim":0.00209,"p.value_classic":1.3e-08,"genes":"ADAM8,AURKB,BCL2L11,BCL6,CASP7,CCL5,CD274,CD74,CTSL,EBF4,FAS,GIMAP8,HCAR2,IDO1,IRF7,JAK3,KITLG,LYN,MERTK,NOD2,P2RX7,PDCD1,RAPGEF2,TNFRSF21"} {"GO.ID":"GO:0002237","Term":"response to molecule of bacterial origin","Annotated":292,"Significant":54,"Expected":17.64,"Rank in p.value_classic":66,"p.value_elim":0.00218,"p.value_classic":9.5e-14,"genes":"ACOD1,B2M,C2,C4B,CARD16,CASP7,CD274,CD40,CD80,CMPK2,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,EDN1,GBP2,GBP3,GBP5,GCH1,GPR31,IDO1,IL12A,IL12RB2,IL18BP,JAK2,KLRK1,LILRA2,LITAF,LTA,LYN,MMP9,NOD2,P2RX7,PDCD1LG2,PDE4B,PLSCR4,PPM1E,PTGER4,RIPK2,SBNO2,SCIMP,SLC11A1,STAP1,TAP2,THBD,TICAM2,TIFAB,TLR10,TNFRSF11A,VCAM1,ZC3H12A"} {"GO.ID":"GO:0031295","Term":"T cell costimulation","Annotated":40,"Significant":8,"Expected":2.42,"Rank in p.value_classic":559,"p.value_elim":0.0023,"p.value_classic":0.00234,"genes":"CD274,CD28,CD80,KLRK1,LYN,PDCD1LG2,TNFRSF14,TNFSF13B"} {"GO.ID":"GO:0001960","Term":"negative regulation of cytokine-mediated signaling pathway","Annotated":68,"Significant":11,"Expected":4.11,"Rank in p.value_classic":560,"p.value_elim":0.00232,"p.value_classic":0.00236,"genes":"CARD16,CCL5,CYLD,IL1RN,NLRC5,OAS3,PADI2,PARP14,STAP1,STAT2,TANK"} {"GO.ID":"GO:0042129","Term":"regulation of T cell proliferation","Annotated":147,"Significant":32,"Expected":8.88,"Rank in p.value_classic":108,"p.value_elim":0.00237,"p.value_classic":1.5e-10,"genes":"BCL6,BTN2A2,CCL5,CD274,CD28,CD80,CTLA4,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12RB1,IL15,IL27,IL4I1,IRF1,JAK2,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0032675","Term":"regulation of interleukin-6 production","Annotated":132,"Significant":17,"Expected":7.97,"Rank in p.value_classic":563,"p.value_elim":0.00241,"p.value_classic":0.00247,"genes":"BANK1,CD74,GHRL,HGF,HLA-B,IFIH1,LILRA2,LPL,NLRP12,NOD2,P2RX7,RIPK2,SCIMP,SLAMF1,TLR7,TLR8,ZC3H12A"} {"GO.ID":"GO:0045581","Term":"negative regulation of T cell differentiation","Annotated":39,"Significant":11,"Expected":2.36,"Rank in p.value_classic":293,"p.value_elim":0.00241,"p.value_classic":0.00001,"genes":"ASCL2,BCL6,CD74,CTLA4,FGL2,IRF1,JAK3,LAG3,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:0060907","Term":"positive regulation of macrophage cytokine production","Annotated":24,"Significant":6,"Expected":1.45,"Rank in p.value_classic":566,"p.value_elim":0.00247,"p.value_classic":0.00251,"genes":"CD74,HLA-G,NOD2,P2RX7,RIPK2,TLR7"} {"GO.ID":"GO:0032691","Term":"negative regulation of interleukin-1 beta production","Annotated":24,"Significant":6,"Expected":1.45,"Rank in p.value_classic":567,"p.value_elim":0.00247,"p.value_classic":0.00251,"genes":"CARD16,CX3CR1,GHRL,MEFV,PML,ZC3H12A"} {"GO.ID":"GO:0030261","Term":"chromosome condensation","Annotated":32,"Significant":7,"Expected":1.93,"Rank in p.value_classic":569,"p.value_elim":0.00251,"p.value_classic":0.00254,"genes":"CDCA5,CDK1,NCAPG,NCAPG2,NCAPH,NUSAP1,TOP2A"} {"GO.ID":"GO:0043372","Term":"positive regulation of CD4-positive, alpha-beta T cell differentiation","Annotated":32,"Significant":7,"Expected":1.93,"Rank in p.value_classic":570,"p.value_elim":0.00251,"p.value_classic":0.00254,"genes":"CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,RIPK2,SOCS1"} {"GO.ID":"GO:0007586","Term":"digestion","Annotated":69,"Significant":11,"Expected":4.17,"Rank in p.value_classic":574,"p.value_elim":0.00261,"p.value_classic":0.00266,"genes":"GCNT3,GHRL,HRH2,NOD2,PGA3,PGA4,PGA5,SLC2A5,SNX10,TIFAB,TYMP"} {"GO.ID":"GO:0033003","Term":"regulation of mast cell activation","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":576,"p.value_elim":0.00264,"p.value_classic":0.00267,"genes":"CD300LF,HAVCR1,LYN,NR4A3,PLSCR1"} {"GO.ID":"GO:0002837","Term":"regulation of immune response to tumor cell","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":577,"p.value_elim":0.00264,"p.value_classic":0.00267,"genes":"CD274,CEACAM1,HLA-DRB1,IL12A,IL4I1"} {"GO.ID":"GO:0032695","Term":"negative regulation of interleukin-12 production","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":578,"p.value_elim":0.00264,"p.value_classic":0.00267,"genes":"JAK3,MEFV,NOD2,SLAMF1,TLR8"} {"GO.ID":"GO:0002643","Term":"regulation of tolerance induction","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":579,"p.value_elim":0.00264,"p.value_classic":0.00267,"genes":"CD274,HLA-B,HLA-G,IDO1,PDCD1"} {"GO.ID":"GO:2001185","Term":"regulation of CD8-positive, alpha-beta T cell activation","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":580,"p.value_elim":0.00264,"p.value_classic":0.00267,"genes":"CD274,HLA-A,HLA-E,IRF1,SOCS1"} {"GO.ID":"GO:0050728","Term":"negative regulation of inflammatory response","Annotated":134,"Significant":17,"Expected":8.09,"Rank in p.value_classic":589,"p.value_elim":0.00283,"p.value_classic":0.0029,"genes":"ACOD1,CDH5,CYLD,GHRL,GPR31,HGF,HLA-DRB1,IL22RA2,KLF4,LYN,MEFV,NLRP12,NOD2,PTGER4,SLAMF8,TNFAIP6,TYRO3"} {"GO.ID":"GO:0002697","Term":"regulation of immune effector process","Annotated":306,"Significant":57,"Expected":18.48,"Rank in p.value_classic":57,"p.value_elim":0.00286,"p.value_classic":1.4e-14,"genes":"APPL2,ASCL2,B2M,BCL6,C3,CD1A,CD1C,CD28,CD74,CD80,CEACAM1,CFH,CR1L,CX3CR1,DDX60,FCN1,FGL2,HLA-A,HLA-B,HLA-C,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL27,IL4I1,IRF4,JAK3,KLRK1,LAG3,LITAF,LTA,LYN,NCF1,NOD2,NR4A3,P2RX7,PARP3,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF8,STAP1,TAP2,TBX21,TICAM2,TLR7,TNFRSF14,ZC3H12A"} {"GO.ID":"GO:0019724","Term":"B cell mediated immunity","Annotated":109,"Significant":25,"Expected":6.58,"Rank in p.value_classic":139,"p.value_elim":0.00286,"p.value_classic":5.1e-09,"genes":"BCL6,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD28,CD40,CD74,CR1L,CSF2RB,EXO1,HLA-E,HLA-G,IRF7,LTA,NOD2,PARP3,SERPING1,TBX21,TLR8,UNG"} {"GO.ID":"GO:1901991","Term":"negative regulation of mitotic cell cycle phase transition","Annotated":169,"Significant":26,"Expected":10.21,"Rank in p.value_classic":283,"p.value_elim":0.00291,"p.value_classic":9.6e-06,"genes":"AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,FAM107A,GTSE1,KLF4,MAD2L1,MUC1,NDC80,NUF2,ORC1,PKMYT1,PML,SPC24,SPC25,TICRR,WEE1,ZWINT"} {"GO.ID":"GO:0002218","Term":"activation of innate immune response","Annotated":257,"Significant":41,"Expected":15.52,"Rank in p.value_classic":149,"p.value_elim":0.00292,"p.value_classic":9.4e-09,"genes":"ACOD1,AIM2,APPL2,AURKB,CD274,CD300LF,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,IFI35,IFIH1,IRF1,IRF4,IRF7,KLRK1,LILRA2,LYN,MEFV,NMI,NOD2,OAS3,PYHIN1,RIPK2,RSAD2,SCIMP,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRIM31,TYRO3,ZBP1,ZNFX1"} {"GO.ID":"GO:0001819","Term":"positive regulation of cytokine production","Annotated":412,"Significant":69,"Expected":24.88,"Rank in p.value_classic":56,"p.value_elim":0.00297,"p.value_classic":5.7e-15,"genes":"ADAM8,AGT,AIM2,B2M,BRCA1,BTN3A1,BTN3A2,C3,CD274,CD28,CD74,CD80,CD83,CLEC6A,CLEC9A,FCN1,GBP5,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL7,IRF1,IRF4,IRF7,ITK,JAK2,KLRK1,LILRA2,LPL,LRRK2,LTA,MCOLN2,MEFV,NLRP12,NOD2,NR4A3,OAS2,OAS3,OSM,P2RX7,PDE4B,PTGER4,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,STAT1,TANK,TBX21,TICAM2,TLR5,TLR7,TLR8,TNFRSF14"} {"GO.ID":"GO:0031640","Term":"killing of cells of another organism","Annotated":33,"Significant":7,"Expected":1.99,"Rank in p.value_classic":592,"p.value_elim":0.00302,"p.value_classic":0.00306,"genes":"APOL1,CCL13,GBP1,GBP2,GBP3,GBP5,GBP7"} {"GO.ID":"GO:0032308","Term":"positive regulation of prostaglandin secretion","Annotated":11,"Significant":4,"Expected":0.66,"Rank in p.value_classic":594,"p.value_elim":0.00307,"p.value_classic":0.00309,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0070673","Term":"response to interleukin-18","Annotated":11,"Significant":4,"Expected":0.66,"Rank in p.value_classic":595,"p.value_elim":0.00307,"p.value_classic":0.00309,"genes":"CASP4,CYLD,RIPK2,TICAM2"} {"GO.ID":"GO:0071349","Term":"cellular response to interleukin-12","Annotated":11,"Significant":4,"Expected":0.66,"Rank in p.value_classic":596,"p.value_elim":0.00307,"p.value_classic":0.00309,"genes":"IL12A,IL12RB1,IL12RB2,JAK2"} {"GO.ID":"GO:0035458","Term":"cellular response to interferon-beta","Annotated":25,"Significant":6,"Expected":1.51,"Rank in p.value_classic":599,"p.value_elim":0.00309,"p.value_classic":0.00313,"genes":"ACOD1,AIM2,IFITM2,IRF1,PYHIN1,STAT1"} {"GO.ID":"GO:0002889","Term":"regulation of immunoglobulin mediated immune response","Annotated":51,"Significant":9,"Expected":3.08,"Rank in p.value_classic":604,"p.value_elim":0.00309,"p.value_classic":0.00315,"genes":"BCL6,C3,CD28,CR1L,HLA-E,LTA,NOD2,PARP3,TBX21"} {"GO.ID":"GO:0050790","Term":"regulation of catalytic activity","Annotated":1172,"Significant":93,"Expected":70.78,"Rank in p.value_classic":610,"p.value_elim":0.00324,"p.value_classic":0.00348,"genes":"ADORA3,AGT,AIM2,AOC3,ATP13A2,AURKB,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CEACAM1,CHTF18,CLSPN,CSF1,CTSL,CTSS,DEPTOR,DHFR,DSCC1,DTNBP1,DTX3L,EDN1,EPHB3,FAS,FGD5,GCH1,GRAMD4,HLA-DRB1,ITK,JAK2,KLF4,KLRK1,LAMP3,LRP5,LRRK2,LYN,MAD2L1,MEFV,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,OAS2,OAS3,PARP3,PARP9,PKIB,PKMYT1,PLAAT4,PLEK,PLSCR1,PLXNA2,PMAIP1,PPM1E,PSMB8,PSMB9,PSME1,PSME2,RALB,RAPGEF2,RASGEF1C,RASGRF1,RIPK2,RSU1,RXFP1,S100A10,SERINC5,SERPING1,SLAMF8,SLC11A1,STMN1,TANK,TGM2,TNFRSF11A,TNFSF10,TYRO3,UHRF1,USP6NL,WARS1"} {"GO.ID":"GO:0055074","Term":"calcium ion homeostasis","Annotated":244,"Significant":26,"Expected":14.74,"Rank in p.value_classic":609,"p.value_elim":0.00334,"p.value_classic":0.00346,"genes":"ANK2,ANKH,ATP13A2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,ERC2,F2RL3,FAM20A,LYN,P2RX7,PML,SNX10,SRI,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0032940","Term":"secretion by cell","Annotated":637,"Significant":62,"Expected":38.47,"Rank in p.value_classic":368,"p.value_elim":0.00343,"p.value_classic":0.00012,"genes":"ADAM8,ADORA3,AGT,ASIC1,ATP13A2,C1QTNF5,CADPS2,CCL5,CCL8,CD38,CEACAM1,COMP,CRHBP,DAB2,DTNBP1,DYSF,EDN1,ERC2,EXOC3L1,EXOC3L4,GHRL,GSDMD,HCAR2,HLA-DRB1,HLA-F,IL12A,IL1RN,ITSN1,JAK2,LRP5,LRRK2,LYN,MCTP2,MERTK,MYOF,NR4A3,OSM,P2RX4,P2RX7,PLEK,PRRT2,RALB,RSAD2,S100A10,S100A13,SCIN,SEPTIN4,SIDT2,SLC16A10,SRI,STX11,STX1A,SUCNR1,SV2B,SYNGR3,SYT1,SYT6,TGM2,TNFAIP2,TNFRSF11A,TYRO3,VEGFC"} {"GO.ID":"GO:0043011","Term":"myeloid dendritic cell differentiation","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":612,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"BATF2,BATF3,IRF4,RELB,UBD"} {"GO.ID":"GO:2000341","Term":"regulation of chemokine (C-X-C motif) ligand 2 production","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":613,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"CD74,KLF4,LPL,MCOLN2,OAS3"} {"GO.ID":"GO:0017121","Term":"plasma membrane phospholipid scrambling","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":614,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"ANO4,P2RX7,PLSCR1,PLSCR4,XKR6"} {"GO.ID":"GO:0035455","Term":"response to interferon-alpha","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":615,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"IFITM1,IFITM2,IFITM3,LAMP3,PYHIN1"} {"GO.ID":"GO:0002689","Term":"negative regulation of leukocyte chemotaxis","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":616,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"KLRK1,PADI2,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0031629","Term":"synaptic vesicle fusion to presynaptic active zone membrane","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":617,"p.value_elim":0.00347,"p.value_classic":0.00351,"genes":"ERC2,PRRT2,STX11,STX1A,SYT1"} {"GO.ID":"GO:0002483","Term":"antigen processing and presentation of endogenous peptide antigen","Annotated":21,"Significant":13,"Expected":1.27,"Rank in p.value_classic":90,"p.value_elim":0.00353,"p.value_classic":1.7e-11,"genes":"B2M,ERAP2,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"GO.ID":"GO:0051783","Term":"regulation of nuclear division","Annotated":127,"Significant":19,"Expected":7.67,"Rank in p.value_classic":390,"p.value_elim":0.0036,"p.value_classic":0.00021,"genes":"AURKB,BIRC5,BUB1B,CD28,CENPF,DAZL,EDN1,HORMAD1,LRP5,MAD2L1,MKI67,NDC80,NPM2,NUF2,NUSAP1,PKMYT1,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0043331","Term":"response to dsRNA","Annotated":43,"Significant":8,"Expected":2.6,"Rank in p.value_classic":626,"p.value_elim":0.0037,"p.value_classic":0.00376,"genes":"COLEC12,IFIH1,NOD2,P2RX7,PMAIP1,RALB,RIPK2,TICAM2"} {"GO.ID":"GO:0034143","Term":"regulation of toll-like receptor 4 signaling pathway","Annotated":26,"Significant":6,"Expected":1.57,"Rank in p.value_classic":629,"p.value_elim":0.00382,"p.value_classic":0.00387,"genes":"ACOD1,APPL2,IFI35,LILRA2,LYN,TICAM2"} {"GO.ID":"GO:0071398","Term":"cellular response to fatty acid","Annotated":26,"Significant":6,"Expected":1.57,"Rank in p.value_classic":630,"p.value_elim":0.00382,"p.value_classic":0.00387,"genes":"DGAT2,EDN1,LPL,PDK4,PID1,ZC3H12A"} {"GO.ID":"GO:0032946","Term":"positive regulation of mononuclear cell proliferation","Annotated":121,"Significant":25,"Expected":7.31,"Rank in p.value_classic":170,"p.value_elim":0.00391,"p.value_classic":4.7e-08,"genes":"BCL6,CCL5,CD274,CD28,CD38,CD74,CD80,CSF1,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12A,IL12RB1,IL15,IL7,JAK2,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"GO.ID":"GO:0016525","Term":"negative regulation of angiogenesis","Annotated":83,"Significant":12,"Expected":5.01,"Rank in p.value_classic":632,"p.value_elim":0.00393,"p.value_classic":0.00401,"genes":"AMOT,CXCL10,E2F2,GHRL,HLA-G,KLF4,MIR503,NPR1,PDE3B,PML,STAT1,THBS2"} {"GO.ID":"GO:0030888","Term":"regulation of B cell proliferation","Annotated":53,"Significant":9,"Expected":3.2,"Rank in p.value_classic":635,"p.value_elim":0.00405,"p.value_classic":0.00411,"genes":"BCL6,CD38,CD74,CTLA4,GPR183,IL7,LYN,TNFRSF21,TNFSF13B"} {"GO.ID":"GO:0002704","Term":"negative regulation of leukocyte mediated immunity","Annotated":55,"Significant":16,"Expected":3.32,"Rank in p.value_classic":178,"p.value_elim":0.00427,"p.value_classic":8.7e-08,"genes":"BCL6,CD80,CEACAM1,CR1L,CX3CR1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,JAK3,NOD2,PARP3,SLAMF1,TBX21"} {"GO.ID":"GO:0045124","Term":"regulation of bone resorption","Annotated":35,"Significant":7,"Expected":2.11,"Rank in p.value_classic":637,"p.value_elim":0.00428,"p.value_classic":0.00434,"genes":"ADAM8,CD38,P2RX7,PDK4,S1PR1,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0061844","Term":"antimicrobial humoral immune response mediated by antimicrobial peptide","Annotated":35,"Significant":7,"Expected":2.11,"Rank in p.value_classic":638,"p.value_elim":0.00428,"p.value_classic":0.00434,"genes":"CCL13,CXCL10,CXCL11,CXCL5,CXCL9,H2BC21,NOD2"} {"GO.ID":"GO:0002687","Term":"positive regulation of leukocyte migration","Annotated":127,"Significant":19,"Expected":7.67,"Rank in p.value_classic":391,"p.value_elim":0.00428,"p.value_classic":0.00021,"genes":"ADAM8,ASCL2,CCL5,CCL7,CCL8,CD74,CSF1,CX3CR1,CXCL10,EDN1,ICAM1,IL12A,KITLG,LYVE1,P2RX4,SLAMF1,TNFRSF14,TNFSF18,VEGFC"} {"GO.ID":"GO:0007218","Term":"neuropeptide signaling pathway","Annotated":44,"Significant":8,"Expected":2.66,"Rank in p.value_classic":639,"p.value_elim":0.00429,"p.value_classic":0.00435,"genes":"CYSLTR1,CYSLTR2,ECEL1,NXPH2,PROK2,RAPGEF2,SSTR2,TYRO3"} {"GO.ID":"GO:0090267","Term":"positive regulation of mitotic cell cycle spindle assembly checkpoint","Annotated":12,"Significant":4,"Expected":0.72,"Rank in p.value_classic":640,"p.value_elim":0.00438,"p.value_classic":0.00442,"genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"GO.ID":"GO:0071888","Term":"macrophage apoptotic process","Annotated":12,"Significant":4,"Expected":0.72,"Rank in p.value_classic":641,"p.value_elim":0.00438,"p.value_classic":0.00442,"genes":"CCL5,CTSL,IRF7,NOD2"} {"GO.ID":"GO:0007567","Term":"parturition","Annotated":12,"Significant":4,"Expected":0.72,"Rank in p.value_classic":642,"p.value_elim":0.00438,"p.value_classic":0.00442,"genes":"CYP1A1,EDN1,MAFF,RXFP1"} {"GO.ID":"GO:2001198","Term":"regulation of dendritic cell differentiation","Annotated":12,"Significant":4,"Expected":0.72,"Rank in p.value_classic":643,"p.value_elim":0.00438,"p.value_classic":0.00442,"genes":"HLA-B,HLA-G,TMEM176A,TMEM176B"} {"GO.ID":"GO:0006213","Term":"pyrimidine nucleoside metabolic process","Annotated":19,"Significant":5,"Expected":1.15,"Rank in p.value_classic":646,"p.value_elim":0.00448,"p.value_classic":0.00453,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,TK1,TYMP"} {"GO.ID":"GO:0002027","Term":"regulation of heart rate","Annotated":74,"Significant":11,"Expected":4.47,"Rank in p.value_classic":650,"p.value_elim":0.00455,"p.value_classic":0.00464,"genes":"ANK2,CAMK2D,EDN1,EPAS1,GCH1,GJD3,KCNE5,KCNJ2,SCN4B,SPTBN4,SRI"} {"GO.ID":"GO:0002548","Term":"monocyte chemotaxis","Annotated":49,"Significant":11,"Expected":2.96,"Rank in p.value_classic":370,"p.value_elim":0.00456,"p.value_classic":0.00013,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CX3CR1,CXCL10,LYN,SLAMF8,TNFRSF11A"} {"GO.ID":"GO:1905820","Term":"positive regulation of chromosome separation","Annotated":27,"Significant":6,"Expected":1.63,"Rank in p.value_classic":652,"p.value_elim":0.00466,"p.value_classic":0.00472,"genes":"AURKB,BIRC5,NCAPG,NCAPG2,NCAPH,PLSCR1"} {"GO.ID":"GO:2000316","Term":"regulation of T-helper 17 type immune response","Annotated":27,"Significant":6,"Expected":1.63,"Rank in p.value_classic":653,"p.value_elim":0.00466,"p.value_classic":0.00472,"genes":"ASCL2,CLEC6A,IL12RB1,JAK2,TBX21,ZC3H12A"} {"GO.ID":"GO:0002719","Term":"negative regulation of cytokine production involved in immune response","Annotated":27,"Significant":6,"Expected":1.63,"Rank in p.value_classic":654,"p.value_elim":0.00466,"p.value_classic":0.00472,"genes":"BCL6,HLA-F,JAK3,NOD2,SLAMF1,TBX21"} {"GO.ID":"GO:0002429","Term":"immune response-activating cell surface receptor signaling pathway","Annotated":245,"Significant":39,"Expected":14.8,"Rank in p.value_classic":159,"p.value_elim":0.00475,"p.value_classic":2.3e-08,"genes":"ACOD1,APPL2,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CD28,CD38,CEACAM1,CLEC6A,CTLA4,CYLD,FCN1,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,IFI35,ITK,KLRK1,LILRA2,LYN,NMI,NOD2,NR4A3,PDE4B,PLPP4,PLSCR1,RIPK2,SCIMP,STAP1,TICAM2,TLR5,TNFRSF21,ZC3H12A"} {"GO.ID":"GO:0050869","Term":"negative regulation of B cell activation","Annotated":28,"Significant":6,"Expected":1.69,"Rank in p.value_classic":667,"p.value_elim":0.00564,"p.value_classic":0.00571,"genes":"BANK1,BCL6,CTLA4,LYN,PARP3,TNFRSF21"} {"GO.ID":"GO:0072539","Term":"T-helper 17 cell differentiation","Annotated":28,"Significant":6,"Expected":1.69,"Rank in p.value_classic":668,"p.value_elim":0.00564,"p.value_classic":0.00571,"genes":"ASCL2,IL12RB1,IRF4,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0086065","Term":"cell communication involved in cardiac conduction","Annotated":46,"Significant":8,"Expected":2.78,"Rank in p.value_classic":674,"p.value_elim":0.00568,"p.value_classic":0.00576,"genes":"ANK2,ATP1B2,CAMK2D,CXADR,KCNE5,SCN4B,SRI,TRDN"} {"GO.ID":"GO:0060396","Term":"growth hormone receptor signaling pathway","Annotated":20,"Significant":5,"Expected":1.21,"Rank in p.value_classic":670,"p.value_elim":0.00569,"p.value_classic":0.00575,"genes":"GHRL,JAK2,JAK3,LYN,PXN"} {"GO.ID":"GO:1901623","Term":"regulation of lymphocyte chemotaxis","Annotated":20,"Significant":5,"Expected":1.21,"Rank in p.value_classic":671,"p.value_elim":0.00569,"p.value_classic":0.00575,"genes":"CCL5,CCL7,CXCL10,KLRK1,PADI2"} {"GO.ID":"GO:0002683","Term":"negative regulation of immune system process","Annotated":409,"Significant":69,"Expected":24.7,"Rank in p.value_classic":54,"p.value_elim":0.00577,"p.value_classic":3.9e-15,"genes":"ACOD1,ASCL2,AURKB,BANK1,BCL6,BTN2A2,CD274,CD300LF,CD74,CD80,CEACAM1,CR1L,CTLA4,CX3CR1,DLL1,FGL1,FGL2,GBP1,GRAMD4,HLA-A,HLA-B,HLA-DOA,HLA-DOB,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IL31RA,IL4I1,IRF1,IRF4,JAK3,KITLG,KLRK1,LAG3,LILRA2,LILRB3,LYN,MEFV,MERTK,NLRC5,NMI,NOD2,OAS3,PADI2,PARP14,PARP3,PDCD1,PDCD1LG2,PTGER4,SERPING1,SLAMF1,SLAMF8,SOCS1,STAP1,STAT2,TAPBPL,TBX21,TMEM176A,TMEM176B,TNFAIP6,TNFRSF14,TNFRSF21,TRAFD1,TRIM31,TSPAN32,TYRO3,ZC3H12A"} {"GO.ID":"GO:2000107","Term":"negative regulation of leukocyte apoptotic process","Annotated":51,"Significant":11,"Expected":3.08,"Rank in p.value_classic":387,"p.value_elim":0.00577,"p.value_classic":0.00019,"genes":"AURKB,BCL6,CCL5,CD74,IDO1,IRF7,JAK3,KITLG,MERTK,NOD2,PDCD1"} {"GO.ID":"GO:0007127","Term":"meiosis I","Annotated":87,"Significant":12,"Expected":5.25,"Rank in p.value_classic":677,"p.value_elim":0.00578,"p.value_classic":0.00589,"genes":"BCL2L11,CCNE2,DMC1,EME1,HORMAD1,MEIKIN,NDC80,RAD54B,RAD54L,TDRD9,TOP2A,ZWINT"} {"GO.ID":"GO:0016045","Term":"detection of bacterium","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":682,"p.value_elim":0.00603,"p.value_classic":0.00608,"genes":"HLA-A,HLA-B,HLA-DRB1,NOD2"} {"GO.ID":"GO:0014821","Term":"phasic smooth muscle contraction","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":683,"p.value_elim":0.00603,"p.value_classic":0.00608,"genes":"EDN1,GHRL,SSTR2,TIFAB"} {"GO.ID":"GO:0001787","Term":"natural killer cell proliferation","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":684,"p.value_elim":0.00603,"p.value_classic":0.00608,"genes":"HLA-E,IL15,JAK2,SLAMF1"} {"GO.ID":"GO:0097254","Term":"renal tubular secretion","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":685,"p.value_elim":0.00603,"p.value_classic":0.00608,"genes":"ABCG2,AGT,EDN1,NPR1"} {"GO.ID":"GO:0002922","Term":"positive regulation of humoral immune response","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":686,"p.value_elim":0.00603,"p.value_classic":0.00608,"genes":"ACOD1,C3,LTA,NOD2"} {"GO.ID":"GO:0019883","Term":"antigen processing and presentation of endogenous antigen","Annotated":28,"Significant":16,"Expected":1.69,"Rank in p.value_classic":73,"p.value_elim":0.00608,"p.value_classic":4.2e-13,"genes":"B2M,CD1A,CD1C,CD74,ERAP2,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP"} {"GO.ID":"GO:0097191","Term":"extrinsic apoptotic signaling pathway","Annotated":205,"Significant":22,"Expected":12.38,"Rank in p.value_classic":693,"p.value_elim":0.0061,"p.value_classic":0.00627,"genes":"AGT,ATF3,BCL2A1,BCL2L11,BCL2L14,BRCA1,CYLD,DEPTOR,FAS,G0S2,HGF,ICAM1,IFI27,IL12A,IL7,JAK2,KITLG,NRP1,P2RX7,PMAIP1,PML,TNFSF10"} {"GO.ID":"GO:0043123","Term":"positive regulation of canonical NF-kappaB signal transduction","Annotated":193,"Significant":21,"Expected":11.66,"Rank in p.value_classic":694,"p.value_elim":0.00622,"p.value_classic":0.0064,"genes":"APOL3,CARD16,CD40,CD74,CLEC6A,CX3CR1,EDA,EDN1,HLA-DRB1,IFIT5,LITAF,NOD2,RIPK2,S100A13,SECTM1,SLC20A1,TICAM2,TIFA,TNFSF10,TRIM22,UBD"} {"GO.ID":"GO:0001776","Term":"leukocyte homeostasis","Annotated":96,"Significant":16,"Expected":5.8,"Rank in p.value_classic":388,"p.value_elim":0.00638,"p.value_classic":0.00019,"genes":"AIM2,BCL2L11,CD74,CSF1,FAS,GPR183,HCAR2,JAK3,KITLG,LYN,MERTK,P2RX7,PDE4B,PMAIP1,SIT1,TNFSF13B"} {"GO.ID":"GO:0030003","Term":"intracellular monoatomic cation homeostasis","Annotated":401,"Significant":37,"Expected":24.22,"Rank in p.value_classic":700,"p.value_elim":0.00639,"p.value_classic":0.00665,"genes":"ANK2,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,ERC2,F2RL3,KCNJ2,LRRK2,LYN,MT2A,OCA2,P2RX7,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC31A2,SLC4A7,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0000075","Term":"cell cycle checkpoint signaling","Annotated":187,"Significant":30,"Expected":11.29,"Rank in p.value_classic":224,"p.value_elim":0.00666,"p.value_classic":8.2e-07,"genes":"AURKB,BIRC5,BRCA1,BUB1B,CDC45,CDC6,CDK1,CDT1,CENPF,CHMP4C,CLSPN,DTL,DTX3L,E2F1,EME1,FBXO6,GTSE1,HORMAD1,MAD2L1,MUC1,NDC80,NUF2,ORC1,PARP9,PML,SPC24,SPC25,TICRR,WDR76,ZWINT"} {"GO.ID":"GO:0046641","Term":"positive regulation of alpha-beta T cell proliferation","Annotated":21,"Significant":5,"Expected":1.27,"Rank in p.value_classic":703,"p.value_elim":0.0071,"p.value_classic":0.00718,"genes":"CD28,HLA-A,HLA-E,JAK2,RIPK2"} {"GO.ID":"GO:1905523","Term":"positive regulation of macrophage migration","Annotated":21,"Significant":5,"Expected":1.27,"Rank in p.value_classic":704,"p.value_elim":0.0071,"p.value_classic":0.00718,"genes":"CCL5,CSF1,CX3CR1,P2RX4,SLAMF1"} {"GO.ID":"GO:0001779","Term":"natural killer cell differentiation","Annotated":21,"Significant":5,"Expected":1.27,"Rank in p.value_classic":705,"p.value_elim":0.0071,"p.value_classic":0.00718,"genes":"IL15,IL15RA,MERTK,SLAMF1,TYRO3"} {"GO.ID":"GO:0001906","Term":"cell killing","Annotated":136,"Significant":34,"Expected":8.21,"Rank in p.value_classic":74,"p.value_elim":0.00716,"p.value_classic":6.3e-13,"genes":"APOL1,B2M,C3,CCL13,CD1A,CD1C,CEACAM1,CFH,CR1L,CX3CR1,GBP1,GBP2,GBP3,GBP5,GBP7,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,RNF19B,SLAMF6,SLAMF7,STAP1,TAP2"} {"GO.ID":"GO:0070527","Term":"platelet aggregation","Annotated":58,"Significant":9,"Expected":3.5,"Rank in p.value_classic":708,"p.value_elim":0.00744,"p.value_classic":0.00756,"genes":"CEACAM1,COMP,F2RL3,FGL1,JAK2,LYN,PLEK,TSPAN32,TYRO3"} {"GO.ID":"GO:0033209","Term":"tumor necrosis factor-mediated signaling pathway","Annotated":101,"Significant":13,"Expected":6.1,"Rank in p.value_classic":709,"p.value_elim":0.00749,"p.value_classic":0.00764,"genes":"AIM2,CARD16,CASP4,CYLD,FAS,JAK2,STAT1,TANK,TIFA,TNFRSF11A,TNFRSF14,TNFSF13B,TNFSF18"} {"GO.ID":"GO:1990830","Term":"cellular response to leukemia inhibitory factor","Annotated":90,"Significant":12,"Expected":5.44,"Rank in p.value_classic":710,"p.value_elim":0.00757,"p.value_classic":0.00772,"genes":"HELLS,ICAM1,INA,KLF4,MRAS,MYBL2,PADI2,PML,SBNO2,SNX10,SOX17,VEGFC"} {"GO.ID":"GO:0043029","Term":"T cell homeostasis","Annotated":39,"Significant":7,"Expected":2.36,"Rank in p.value_classic":711,"p.value_elim":0.00794,"p.value_classic":0.00805,"genes":"AIM2,BCL2L11,FAS,JAK3,P2RX7,PMAIP1,SIT1"} {"GO.ID":"GO:0032689","Term":"negative regulation of type II interferon production","Annotated":30,"Significant":6,"Expected":1.81,"Rank in p.value_classic":714,"p.value_elim":0.00802,"p.value_classic":0.00812,"genes":"CD274,HLA-DRB1,NOD2,PDCD1LG2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:0070206","Term":"protein trimerization","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":716,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"ASIC1,CD74,HLA-G,STEAP4"} {"GO.ID":"GO:0051770","Term":"positive regulation of nitric-oxide synthase biosynthetic process","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":717,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"JAK2,LRRK2,NOD2,STAT1"} {"GO.ID":"GO:0048532","Term":"anatomical structure arrangement","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":718,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"DAB1,DLL1,EGR2,NRP1"} {"GO.ID":"GO:0055119","Term":"relaxation of cardiac muscle","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":719,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"CAMK2D,KCNJ2,P2RX4,PDE4B"} {"GO.ID":"GO:0016553","Term":"base conversion or substitution editing","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":720,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"ADARB2,APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0002903","Term":"negative regulation of B cell apoptotic process","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":721,"p.value_elim":0.00805,"p.value_classic":0.00812,"genes":"AURKB,BCL6,CD74,PDCD1"} {"GO.ID":"GO:0002761","Term":"regulation of myeloid leukocyte differentiation","Annotated":102,"Significant":13,"Expected":6.16,"Rank in p.value_classic":726,"p.value_elim":0.00812,"p.value_classic":0.00829,"genes":"CD101,CD74,CEACAM1,CSF1,HLA-DRB1,IRF7,KITLG,LILRB3,LYN,TAL1,TESC,TNFAIP6,TNFRSF11A"} {"GO.ID":"GO:0071897","Term":"DNA biosynthetic process","Annotated":173,"Significant":19,"Expected":10.45,"Rank in p.value_classic":727,"p.value_elim":0.00816,"p.value_classic":0.00837,"genes":"AURKB,CCNA2,CENPF,CHTF18,DSCC1,DTL,GCH1,HGF,JADE2,KLF4,PARP10,PARP3,PCLAF,PKIB,POLB,POLE2,TK1,TYMS,XRN1"} {"GO.ID":"GO:0006270","Term":"DNA replication initiation","Annotated":36,"Significant":12,"Expected":2.17,"Rank in p.value_classic":221,"p.value_elim":0.00846,"p.value_classic":7.1e-07,"genes":"CCNE2,CDC45,CDC6,CDT1,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,ORC1,TICRR"} {"GO.ID":"GO:0051046","Term":"regulation of secretion","Annotated":463,"Significant":44,"Expected":27.96,"Rank in p.value_classic":543,"p.value_elim":0.00871,"p.value_classic":0.00186,"genes":"ADAM8,ADORA3,AGT,ASIC1,ATP13A2,CADPS2,CCL5,CD38,CD74,CEACAM1,CRHBP,DAB2,DTNBP1,DYSF,EDN1,GHRL,HCAR2,HLA-DRB1,HLA-F,IL12A,JAK2,LRP5,LRRK2,LYN,MCTP2,MYOF,NPR1,OAS2,OSM,P2RX4,P2RX7,RSAD2,S100A10,SCIN,SEPTIN4,SIDT2,SRI,STX1A,SV2B,SYT1,SYT6,TIFAB,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0062207","Term":"regulation of pattern recognition receptor signaling pathway","Annotated":141,"Significant":20,"Expected":8.52,"Rank in p.value_classic":415,"p.value_elim":0.00873,"p.value_classic":0.00031,"genes":"ACOD1,APPL2,AURKB,CD300LF,DDX60,GBP2,GBP5,GRAMD4,IFI35,IRF1,IRF4,IRF7,LILRA2,LYN,MEFV,NOD2,RSAD2,TICAM2,TRIM31,TYRO3"} {"GO.ID":"GO:0009219","Term":"pyrimidine deoxyribonucleotide metabolic process","Annotated":22,"Significant":5,"Expected":1.33,"Rank in p.value_classic":733,"p.value_elim":0.00874,"p.value_classic":0.00883,"genes":"CMPK2,DPYS,TYMP,TYMS,UNG"} {"GO.ID":"GO:0043373","Term":"CD4-positive, alpha-beta T cell lineage commitment","Annotated":22,"Significant":5,"Expected":1.33,"Rank in p.value_classic":734,"p.value_elim":0.00874,"p.value_classic":0.00883,"genes":"CTSL,IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0002407","Term":"dendritic cell chemotaxis","Annotated":22,"Significant":5,"Expected":1.33,"Rank in p.value_classic":735,"p.value_elim":0.00874,"p.value_classic":0.00883,"genes":"CCL5,GPR183,IL12A,SLAMF1,SLAMF8"} {"GO.ID":"GO:0090025","Term":"regulation of monocyte chemotaxis","Annotated":22,"Significant":5,"Expected":1.33,"Rank in p.value_classic":736,"p.value_elim":0.00874,"p.value_classic":0.00883,"genes":"CCL5,CX3CR1,CXCL10,LYN,SLAMF8"} {"GO.ID":"GO:0033047","Term":"regulation of mitotic sister chromatid segregation","Annotated":52,"Significant":11,"Expected":3.14,"Rank in p.value_classic":394,"p.value_elim":0.00894,"p.value_classic":0.00022,"genes":"AURKB,BIRC5,BUB1B,CDK1,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0006952","Term":"defense response","Annotated":1352,"Significant":201,"Expected":81.65,"Rank in p.value_classic":8,"p.value_elim":0.00901,"genes":"ACOD1,ADAM8,ADGRE5,ADORA3,AGR2,AGT,AIM2,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APPL2,ASIC1,AURKB,BATF2,BCL6,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD163,CD274,CD28,CD300LF,CD40,CD74,CD83,CDH5,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CRHBP,CSF1,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,DDX60,DTX3L,EDN1,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GGT5,GHRL,GPR31,GRAMD4,GSDMA,GSDMD,H2BC21,HGF,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL1RN,IL22RA2,IL27,IL31RA,IL32,IRF1,IRF4,IRF7,ISG20,ITK,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LGALS3BP,LILRA1,LILRA2,LILRB3,LPL,LRRK2,LTA,LY75,LYN,MCOLN2,MEFV,MMP25,MMP9,MSRB1,NCF1,NLRC5,NLRP12,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,OSM,P2RX7,PARP14,PARP9,PLSCR1,PMAIP1,PML,POLB,PROK2,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SBNO2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SP140,STAP1,STAT1,STAT2,SUCNR1,TANK,TAP1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF8,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,VCAM1,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0046631","Term":"alpha-beta T cell activation","Annotated":148,"Significant":31,"Expected":8.94,"Rank in p.value_classic":122,"p.value_elim":0.00903,"p.value_classic":8.2e-10,"genes":"ASCL2,BCL6,CD274,CD28,CD80,CD83,CTSL,GPR183,HLA-A,HLA-DRA,HLA-DRB1,HLA-E,IL12A,IL12RB1,IL15,IL27,IRF1,IRF4,ITK,JAK2,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFRSF14,TNFSF8,ZC3H12A"} {"GO.ID":"GO:0071622","Term":"regulation of granulocyte chemotaxis","Annotated":40,"Significant":7,"Expected":2.42,"Rank in p.value_classic":741,"p.value_elim":0.00914,"p.value_classic":0.00926,"genes":"CCL5,CD74,CSF1,EDN1,NOD2,SLAMF1,TNFAIP6"} {"GO.ID":"GO:0071353","Term":"cellular response to interleukin-4","Annotated":31,"Significant":6,"Expected":1.87,"Rank in p.value_classic":742,"p.value_elim":0.00945,"p.value_classic":0.00956,"genes":"CD300LF,JAK3,MCM2,PARP14,PML,RUFY4"} {"GO.ID":"GO:0002475","Term":"antigen processing and presentation via MHC class Ib","Annotated":21,"Significant":10,"Expected":1.27,"Rank in p.value_classic":183,"p.value_elim":0.00949,"p.value_classic":1.2e-07,"genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP2"} {"GO.ID":"GO:0002507","Term":"tolerance induction","Annotated":25,"Significant":8,"Expected":1.51,"Rank in p.value_classic":351,"p.value_elim":0.00957,"p.value_classic":0.00007,"genes":"ACOD1,CD274,HLA-B,HLA-E,HLA-G,IDO1,LYN,PDCD1"} {"GO.ID":"GO:0006275","Term":"regulation of DNA replication","Annotated":119,"Significant":20,"Expected":7.19,"Rank in p.value_classic":320,"p.value_elim":0.00967,"p.value_classic":0.00003,"genes":"BAZ1A,BCL6,CCNA2,CDC25A,CDC6,CDK1,CDT1,CHTF18,DSCC1,E2F8,ESCO2,JADE2,MCM2,MCM4,MCM5,MCM6,MCM7,NPM2,TICRR,WEE1"} {"GO.ID":"GO:0007093","Term":"mitotic cell cycle checkpoint signaling","Annotated":139,"Significant":22,"Expected":8.39,"Rank in p.value_classic":321,"p.value_elim":0.00988,"p.value_classic":0.00003,"genes":"AURKB,BIRC5,BRCA1,BUB1B,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,EME1,GTSE1,MAD2L1,MUC1,NDC80,NUF2,ORC1,PML,SPC24,SPC25,TICRR,ZWINT"} {"GO.ID":"GO:0006874","Term":"intracellular calcium ion homeostasis","Annotated":227,"Significant":23,"Expected":13.71,"Rank in p.value_classic":748,"p.value_elim":0.01006,"p.value_classic":0.01035,"genes":"ANK2,ATP13A2,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,ERC2,F2RL3,LYN,P2RX7,PML,SRI,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0042127","Term":"regulation of cell population proliferation","Annotated":1319,"Significant":123,"Expected":79.66,"Rank in p.value_classic":212,"p.value_elim":0.01007,"p.value_classic":4.4e-07,"genes":"ADORA3,AGT,APPL2,ASCL2,ATF3,ATF5,B2M,BCL6,BIRC5,BTN2A2,CCL5,CCL8,CCNA2,CD274,CD28,CD38,CD74,CD80,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CEACAM1,CHRD,COMP,CSF1,CSF2RB,CTLA4,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYSLTR1,DAB2,DLL1,E2F1,EDN1,FLT3LG,GAREM1,GHRL,GPR183,HAPLN3,HBEGF,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,JAK2,KITLG,KLF4,LBH,LRP5,LRRK2,LTA,LYN,MARCKSL1,MIR503,MMP9,MTSS1,NMI,NOD2,NPR1,NR4A3,NRP1,OSM,OVOL1,PARP10,PDCD1LG2,PID1,PIM1,PLAAT4,PLCD3,PML,PRC1,PTPRU,RAPGEF2,RIPK2,S100A13,S1PR1,SCIN,SHCBP1,SLAMF1,SOX17,SSBP3,SSTR2,STAT1,STAT2,SYNE1,TAL1,TESC,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,UHRF1,VCAM1,VCAN,VEGFC,WARS1,WDR62"} {"GO.ID":"GO:0044093","Term":"positive regulation of molecular function","Annotated":1029,"Significant":80,"Expected":62.15,"Rank in p.value_classic":762,"p.value_elim":0.01017,"p.value_classic":0.0108,"genes":"ABCB1,ADORA3,AGT,AIM2,ANK2,ATP1B2,AURKB,B2M,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CDT1,CHTF18,CLSPN,CSF1,CTSL,CTSS,DHFR,DSCC1,DTX3L,EDA,EDN1,FAS,GCH1,GRAMD4,HLA-DRB1,ITK,JAK2,KLF4,LRRK2,LYN,MEFV,MERTK,MMD,MMP9,NCF1,NLRP12,NOD2,NRP1,PARP9,PKIB,PLAAT4,PLEK,PLSCR1,PMAIP1,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RHEBL1,RIPK2,RSU1,RXFP1,S100A10,SERINC5,SLC11A1,STMN1,SYNGR3,TANK,TESC,TGM2,TICAM2,TNFRSF11A,TNFSF10,TNFSF18,TRDN,TRIM22,TRIM31,TYRO3,UHRF1,USP6NL"} {"GO.ID":"GO:0050671","Term":"positive regulation of lymphocyte proliferation","Annotated":118,"Significant":24,"Expected":7.13,"Rank in p.value_classic":184,"p.value_elim":0.01023,"p.value_classic":1.2e-07,"genes":"BCL6,CCL5,CD274,CD28,CD38,CD74,CD80,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12A,IL12RB1,IL15,IL7,JAK2,KITLG,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"GO.ID":"GO:0072677","Term":"eosinophil migration","Annotated":22,"Significant":8,"Expected":1.33,"Rank in p.value_classic":318,"p.value_elim":0.01031,"p.value_classic":0.00003,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,PTGER4"} {"GO.ID":"GO:0072678","Term":"T cell migration","Annotated":61,"Significant":9,"Expected":3.68,"Rank in p.value_classic":749,"p.value_elim":0.01033,"p.value_classic":0.01049,"genes":"ADAM8,ASCL2,CCL5,CXCL10,CXCL11,GPR183,ICAM1,S1PR1,TNFRSF14"} {"GO.ID":"GO:0002371","Term":"dendritic cell cytokine production","Annotated":15,"Significant":4,"Expected":0.91,"Rank in p.value_classic":751,"p.value_elim":0.01046,"p.value_classic":0.01055,"genes":"JAK3,NOD2,SCIMP,TICAM2"} {"GO.ID":"GO:0042454","Term":"ribonucleoside catabolic process","Annotated":15,"Significant":4,"Expected":0.91,"Rank in p.value_classic":752,"p.value_elim":0.01046,"p.value_classic":0.01055,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4"} {"GO.ID":"GO:0051447","Term":"negative regulation of meiotic cell cycle","Annotated":15,"Significant":4,"Expected":0.91,"Rank in p.value_classic":753,"p.value_elim":0.01046,"p.value_classic":0.01055,"genes":"HORMAD1,OVOL1,PKMYT1,ZWINT"} {"GO.ID":"GO:0002730","Term":"regulation of dendritic cell cytokine production","Annotated":15,"Significant":4,"Expected":0.91,"Rank in p.value_classic":754,"p.value_elim":0.01046,"p.value_classic":0.01055,"genes":"JAK3,NOD2,SCIMP,TICAM2"} {"GO.ID":"GO:0002544","Term":"chronic inflammatory response","Annotated":15,"Significant":4,"Expected":0.91,"Rank in p.value_classic":755,"p.value_elim":0.01046,"p.value_classic":0.01055,"genes":"CCL5,IDO1,LTA,VCAM1"} {"GO.ID":"GO:0045740","Term":"positive regulation of DNA replication","Annotated":41,"Significant":7,"Expected":2.48,"Rank in p.value_classic":757,"p.value_elim":0.01046,"p.value_classic":0.0106,"genes":"BAZ1A,CDC25A,CDK1,CDT1,E2F8,NPM2,WEE1"} {"GO.ID":"GO:0032740","Term":"positive regulation of interleukin-17 production","Annotated":23,"Significant":5,"Expected":1.39,"Rank in p.value_classic":758,"p.value_elim":0.01063,"p.value_classic":0.01074,"genes":"IL15,JAK2,NOD2,OSM,SLAMF6"} {"GO.ID":"GO:0002675","Term":"positive regulation of acute inflammatory response","Annotated":23,"Significant":5,"Expected":1.39,"Rank in p.value_classic":759,"p.value_elim":0.01063,"p.value_classic":0.01074,"genes":"ADAM8,C3,HLA-E,OSM,TNFRSF11A"} {"GO.ID":"GO:0032092","Term":"positive regulation of protein binding","Annotated":51,"Significant":8,"Expected":3.08,"Rank in p.value_classic":761,"p.value_elim":0.01064,"p.value_classic":0.0108,"genes":"B2M,DTX3L,LRRK2,MMP9,NRP1,RALB,RAPGEF2,RIPK2"} {"GO.ID":"GO:0007094","Term":"mitotic spindle assembly checkpoint signaling","Annotated":44,"Significant":10,"Expected":2.66,"Rank in p.value_classic":397,"p.value_elim":0.01084,"p.value_classic":0.00023,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0071173","Term":"spindle assembly checkpoint signaling","Annotated":44,"Significant":10,"Expected":2.66,"Rank in p.value_classic":398,"p.value_elim":0.01084,"p.value_classic":0.00023,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0071174","Term":"mitotic spindle checkpoint signaling","Annotated":44,"Significant":10,"Expected":2.66,"Rank in p.value_classic":399,"p.value_elim":0.01084,"p.value_classic":0.00023,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0007259","Term":"receptor signaling pathway via JAK-STAT","Annotated":127,"Significant":22,"Expected":7.67,"Rank in p.value_classic":276,"p.value_elim":0.01091,"p.value_classic":6.7e-06,"genes":"AGT,CCL5,CD40,CSF2RB,DAB1,GBP7,IL12A,IL15,IL15RA,IL22RA2,IL31RA,JAK2,JAK3,LYN,NMI,OSM,PARP14,PARP9,SOCS1,STAT1,STAT2,TNFSF18"} {"GO.ID":"GO:0002758","Term":"innate immune response-activating signaling pathway","Annotated":238,"Significant":38,"Expected":14.37,"Rank in p.value_classic":163,"p.value_elim":0.01094,"p.value_classic":3.2e-08,"genes":"ACOD1,AIM2,APPL2,AURKB,CD274,CD300LF,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,IFI35,IFIH1,IRF1,IRF4,IRF7,KLRK1,LILRA2,LYN,MEFV,NMI,NOD2,OAS3,RIPK2,RSAD2,SCIMP,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRIM31,TYRO3"} {"GO.ID":"GO:0032743","Term":"positive regulation of interleukin-2 production","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":771,"p.value_elim":0.01105,"p.value_classic":0.01118,"genes":"CD28,CD80,CD83,IRF4,PDE4B,RIPK2"} {"GO.ID":"GO:0051281","Term":"positive regulation of release of sequestered calcium ion into cytosol","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":772,"p.value_elim":0.01105,"p.value_classic":0.01118,"genes":"CXCL10,CXCL11,CXCL9,F2RL3,SRI,TRDN"} {"GO.ID":"GO:0072529","Term":"pyrimidine-containing compound catabolic process","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":773,"p.value_elim":0.01105,"p.value_classic":0.01118,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,DPYS,TYMP,UNG"} {"GO.ID":"GO:1904427","Term":"positive regulation of calcium ion transmembrane transport","Annotated":62,"Significant":9,"Expected":3.74,"Rank in p.value_classic":779,"p.value_elim":0.01146,"p.value_classic":0.01164,"genes":"ANK2,CXCL10,CXCL11,CXCL9,F2RL3,P2RX4,P2RX7,SRI,TRDN"} {"GO.ID":"GO:0071677","Term":"positive regulation of mononuclear cell migration","Annotated":62,"Significant":9,"Expected":3.74,"Rank in p.value_classic":780,"p.value_elim":0.01146,"p.value_classic":0.01164,"genes":"ADAM8,ASCL2,CCL5,CCL7,CX3CR1,CXCL10,IL12A,SLAMF1,TNFRSF14"} {"GO.ID":"GO:0007155","Term":"cell adhesion","Annotated":1194,"Significant":126,"Expected":72.11,"Rank in p.value_classic":111,"p.value_elim":0.01191,"p.value_classic":1.8e-10,"genes":"ADAM8,ADGRE5,AGR2,ANTXR1,AOC3,ASCL2,ATP1B2,B2M,BCL2L11,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CD93,CDH5,CEACAM1,CELSR1,CHRD,COMP,CSF1,CTLA4,CX3CR1,CXADR,CXCR3,CYLD,DAB1,DAB2,DLL1,EDA,EPHB3,F2RL3,FAM107A,FGL1,FGL2,GBP1,GLDN,HAPLN3,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,ICAM1,ICAM2,IDO1,IL12A,IL12RB1,IL15,IL1RN,IL32,IL4I1,IL7,IRF1,ITGA7,ITGB5,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LAMB3,LGALS3BP,LRP5,LYN,LYVE1,MDGA1,MERTK,MIR503,MPZL2,MTSS1,MUC1,NOD2,NR4A3,NRCAM,NRP1,ONECUT2,PCDH12,PCDHGC3,PDCD1LG2,PDE3B,PLEK,PLXNA2,PML,PRKX,PTPRU,PXN,RIPK2,RSU1,S100A10,S1PR1,SCARF1,SELL,SIGLEC12,SLAMF1,SLAMF7,SOCS1,SSPN,TBX21,TESC,TGM2,THBS2,TNFAIP6,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TSPAN32,TYRO3,VCAM1,VCAN,ZC3H12A"} {"GO.ID":"GO:0019226","Term":"transmission of nerve impulse","Annotated":42,"Significant":7,"Expected":2.54,"Rank in p.value_classic":783,"p.value_elim":0.01192,"p.value_classic":0.01208,"genes":"GHRL,NRCAM,P2RX4,S1PR1,SCN4B,SPTBN4,TYMP"} {"GO.ID":"GO:0031663","Term":"lipopolysaccharide-mediated signaling pathway","Annotated":52,"Significant":8,"Expected":3.14,"Rank in p.value_classic":787,"p.value_elim":0.01193,"p.value_classic":0.0121,"genes":"ACOD1,CARD16,LILRA2,LYN,RIPK2,SCIMP,TICAM2,TIFAB"} {"GO.ID":"GO:0008608","Term":"attachment of spindle microtubules to kinetochore","Annotated":52,"Significant":8,"Expected":3.14,"Rank in p.value_classic":788,"p.value_elim":0.01193,"p.value_classic":0.0121,"genes":"AURKB,BIRC5,CDT1,EML4,NDC80,NUF2,SPC24,SPC25"} {"GO.ID":"GO:0007088","Term":"regulation of mitotic nuclear division","Annotated":108,"Significant":16,"Expected":6.52,"Rank in p.value_classic":476,"p.value_elim":0.01208,"p.value_classic":0.00074,"genes":"AURKB,BIRC5,BUB1B,CD28,CENPF,EDN1,LRP5,MAD2L1,MKI67,NDC80,NUF2,NUSAP1,PKMYT1,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0002824","Term":"positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":109,"Significant":28,"Expected":6.58,"Rank in p.value_classic":96,"p.value_elim":0.01232,"p.value_classic":3.5e-11,"genes":"B2M,C3,CD1A,CD1C,CD274,CD28,CLEC6A,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,JAK2,LTA,NOD2,P2RX7,RIPK2,RSAD2,SLAMF1,SLC11A1,TAP2,TBX21,TNFSF13B"} {"GO.ID":"GO:0002705","Term":"positive regulation of leukocyte mediated immunity","Annotated":121,"Significant":28,"Expected":7.31,"Rank in p.value_classic":118,"p.value_elim":0.01244,"p.value_classic":4.9e-10,"genes":"B2M,C3,CD1A,CD1C,CD28,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,KLRK1,LAG3,LTA,NOD2,P2RX7,RSAD2,SCIMP,SLAMF1,SLAMF6,STAP1,TAP2,TBX21,TICAM2"} {"GO.ID":"GO:0031577","Term":"spindle checkpoint signaling","Annotated":45,"Significant":10,"Expected":2.72,"Rank in p.value_classic":409,"p.value_elim":0.01259,"p.value_classic":0.00028,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0051279","Term":"regulation of release of sequestered calcium ion into cytosol","Annotated":63,"Significant":9,"Expected":3.8,"Rank in p.value_classic":790,"p.value_elim":0.01267,"p.value_classic":0.01287,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,SRI,TRDN"} {"GO.ID":"GO:0051315","Term":"attachment of mitotic spindle microtubules to kinetochore","Annotated":24,"Significant":5,"Expected":1.45,"Rank in p.value_classic":791,"p.value_elim":0.01277,"p.value_classic":0.01291,"genes":"AURKB,BIRC5,CDT1,NDC80,NUF2"} {"GO.ID":"GO:0002726","Term":"positive regulation of T cell cytokine production","Annotated":24,"Significant":5,"Expected":1.45,"Rank in p.value_classic":792,"p.value_elim":0.01277,"p.value_classic":0.01291,"genes":"B2M,HLA-A,RSAD2,SLAMF1,TBX21"} {"GO.ID":"GO:0002369","Term":"T cell cytokine production","Annotated":33,"Significant":6,"Expected":1.99,"Rank in p.value_classic":794,"p.value_elim":0.01284,"p.value_classic":0.01299,"genes":"B2M,HLA-A,HLA-F,RSAD2,SLAMF1,TBX21"} {"GO.ID":"GO:0002724","Term":"regulation of T cell cytokine production","Annotated":33,"Significant":6,"Expected":1.99,"Rank in p.value_classic":795,"p.value_elim":0.01284,"p.value_classic":0.01299,"genes":"B2M,HLA-A,HLA-F,RSAD2,SLAMF1,TBX21"} {"GO.ID":"GO:0052547","Term":"regulation of peptidase activity","Annotated":232,"Significant":23,"Expected":14.01,"Rank in p.value_classic":800,"p.value_elim":0.01286,"p.value_classic":0.01322,"genes":"AIM2,ATP13A2,CARD16,CTSL,CTSS,FAS,GRAMD4,JAK2,KLF4,LAMP3,LYN,MEFV,MMP9,NLRP12,PMAIP1,PSMB8,PSMB9,PSME1,PSME2,RIPK2,SERPING1,TANK,TNFSF10"} {"GO.ID":"GO:0015698","Term":"inorganic anion transport","Annotated":108,"Significant":13,"Expected":6.52,"Rank in p.value_classic":799,"p.value_elim":0.01287,"p.value_classic":0.01313,"genes":"ABCB1,ANKH,ANO4,APOL1,ATP8B1,CLIC5,GABRA3,OCA2,SLC11A1,SLC12A3,SLC20A1,SLC37A1,SLC4A7"} {"GO.ID":"GO:0002220","Term":"innate immune response activating cell surface receptor signaling pathway","Annotated":79,"Significant":14,"Expected":4.77,"Rank in p.value_classic":401,"p.value_elim":0.01292,"p.value_classic":0.00024,"genes":"ACOD1,APPL2,CLEC6A,FCN1,IFI35,KLRK1,LILRA2,LYN,NMI,NOD2,RIPK2,SCIMP,TICAM2,TLR5"} {"GO.ID":"GO:0019884","Term":"antigen processing and presentation of exogenous antigen","Annotated":46,"Significant":23,"Expected":2.78,"Rank in p.value_classic":39,"p.value_elim":0.01307,"p.value_classic":1.5e-16,"genes":"B2M,CD1A,CD1C,CD74,CTSL,CTSS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,PSME1,TAP2"} {"GO.ID":"GO:0030449","Term":"regulation of complement activation","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":801,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"C3,CFH,CR1L,SERPING1"} {"GO.ID":"GO:0045655","Term":"regulation of monocyte differentiation","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":802,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"CD74,CSF1,HLA-DRB1,IRF7"} {"GO.ID":"GO:0033033","Term":"negative regulation of myeloid cell apoptotic process","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":803,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"CCL5,IRF7,KITLG,NOD2"} {"GO.ID":"GO:0002756","Term":"MyD88-independent toll-like receptor signaling pathway","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":804,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"CD274,CD300LF,IRF7,TICAM2"} {"GO.ID":"GO:0002830","Term":"positive regulation of type 2 immune response","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":805,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"CD74,IDO1,NOD2,RSAD2"} {"GO.ID":"GO:0072540","Term":"T-helper 17 cell lineage commitment","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":806,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0045822","Term":"negative regulation of heart contraction","Annotated":16,"Significant":4,"Expected":0.97,"Rank in p.value_classic":807,"p.value_elim":0.01329,"p.value_classic":0.0134,"genes":"GJD3,SPTBN4,SRI,ZC3H12A"} {"GO.ID":"GO:0051310","Term":"metaphase chromosome alignment","Annotated":97,"Significant":12,"Expected":5.86,"Rank in p.value_classic":809,"p.value_elim":0.01346,"p.value_classic":0.01371,"genes":"AURKB,BIRC5,CDCA5,CDT1,CENPF,CHMP4C,EML4,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0002707","Term":"negative regulation of lymphocyte mediated immunity","Annotated":45,"Significant":14,"Expected":2.72,"Rank in p.value_classic":200,"p.value_elim":0.01349,"p.value_classic":2.2e-07,"genes":"BCL6,CD80,CEACAM1,CR1L,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,NOD2,PARP3,SLAMF1,TBX21"} {"GO.ID":"GO:0031570","Term":"DNA integrity checkpoint signaling","Annotated":131,"Significant":18,"Expected":7.91,"Rank in p.value_classic":481,"p.value_elim":0.01352,"p.value_classic":0.00088,"genes":"BRCA1,CDC45,CDC6,CDK1,CDT1,CLSPN,DTL,DTX3L,E2F1,EME1,FBXO6,GTSE1,MUC1,ORC1,PARP9,PML,TICRR,WDR76"} {"GO.ID":"GO:0002274","Term":"myeloid leukocyte activation","Annotated":199,"Significant":32,"Expected":12.02,"Rank in p.value_classic":207,"p.value_elim":0.01354,"p.value_classic":3.3e-07,"genes":"BATF2,BATF3,CCL5,CD300LF,CD74,CD93,CSF1,CX3CR1,DYSF,HAVCR1,IFI35,IL15,IL31RA,IRF4,JAK2,KARS1,LILRA2,LRRK2,LYN,NMI,NR4A3,PLSCR1,RELB,S100A13,SBNO2,SLAMF1,SLC11A1,STAP1,SUCNR1,TSPAN32,UBD,ZC3H12A"} {"GO.ID":"GO:0051301","Term":"cell division","Annotated":576,"Significant":48,"Expected":34.79,"Rank in p.value_classic":815,"p.value_elim":0.0137,"p.value_classic":0.0143,"genes":"ANLN,AURKB,BIRC5,BUB1B,CCNA2,CCNE2,CCNF,CDC25A,CDC6,CDCA3,CDCA5,CDK1,CDT1,CENPF,CHMP4C,DLL1,DYNLT1,E2F8,EML4,ERCC6L,GAREM1,HELLS,IQGAP3,KIF11,KIF18B,KIF23,LBH,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,OIP5,OSM,PRC1,RALB,SEPTIN4,SOX17,SPC24,SPC25,STMN1,TAL1,TOP2A,VEGFC,WEE1,ZWINT"} {"GO.ID":"GO:0002577","Term":"regulation of antigen processing and presentation","Annotated":19,"Significant":7,"Expected":1.15,"Rank in p.value_classic":352,"p.value_elim":0.01375,"p.value_classic":0.00008,"genes":"CD74,FGL2,HLA-DOA,HLA-DOB,NOD2,SLC11A1,TAPBPL"} {"GO.ID":"GO:0000082","Term":"G1/S transition of mitotic cell cycle","Annotated":195,"Significant":20,"Expected":11.78,"Rank in p.value_classic":813,"p.value_elim":0.01387,"p.value_classic":0.01422,"genes":"APPL2,BTN2A2,CCNA2,CCNE2,CDC25A,CDC6,CDK1,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,IQGAP3,KLF4,MUC1,PML,PSME1,PSME2,RRM2,WEE1"} {"GO.ID":"GO:0009308","Term":"amine metabolic process","Annotated":86,"Significant":11,"Expected":5.19,"Rank in p.value_classic":812,"p.value_elim":0.0139,"p.value_classic":0.01414,"genes":"AOC3,CYP1A1,EPAS1,GCH1,IDO1,IDO2,IL4I1,NAAA,NPR1,SAT1,VCAM1"} {"GO.ID":"GO:0050921","Term":"positive regulation of chemotaxis","Annotated":121,"Significant":14,"Expected":7.31,"Rank in p.value_classic":814,"p.value_elim":0.014,"p.value_classic":0.01428,"genes":"CCL5,CCL7,CD74,CSF1,CX3CR1,CXCL10,EDN1,IL12A,NRP1,P2RX4,S1PR1,SLAMF1,SUCNR1,VEGFC"} {"GO.ID":"GO:0045089","Term":"positive regulation of innate immune response","Annotated":308,"Significant":52,"Expected":18.6,"Rank in p.value_classic":88,"p.value_elim":0.01424,"p.value_classic":1.1e-11,"genes":"ACOD1,ADAM8,AIM2,APPL2,AURKB,CCL5,CD274,CD300LF,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,HLA-E,HLA-F,HLA-G,IFI35,IFIH1,IL12A,IRF1,IRF4,IRF7,KLRK1,LAG3,LILRA2,LYN,MEFV,NLRC5,NMI,NOD2,OAS3,PARP9,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SLAMF6,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRIM31,TYRO3,ZBP1,ZNFX1"} {"GO.ID":"GO:0033046","Term":"negative regulation of sister chromatid segregation","Annotated":46,"Significant":10,"Expected":2.78,"Rank in p.value_classic":423,"p.value_elim":0.01454,"p.value_classic":0.00034,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0033048","Term":"negative regulation of mitotic sister chromatid segregation","Annotated":46,"Significant":10,"Expected":2.78,"Rank in p.value_classic":424,"p.value_elim":0.01454,"p.value_classic":0.00034,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:2000816","Term":"negative regulation of mitotic sister chromatid separation","Annotated":46,"Significant":10,"Expected":2.78,"Rank in p.value_classic":425,"p.value_elim":0.01454,"p.value_classic":0.00034,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0045841","Term":"negative regulation of mitotic metaphase/anaphase transition","Annotated":46,"Significant":10,"Expected":2.78,"Rank in p.value_classic":426,"p.value_elim":0.01454,"p.value_classic":0.00034,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0006968","Term":"cellular defense response","Annotated":34,"Significant":6,"Expected":2.05,"Rank in p.value_classic":816,"p.value_elim":0.01482,"p.value_classic":0.01499,"genes":"CX3CR1,CXCL9,HLA-G,ITK,LGALS3BP,NCF1"} {"GO.ID":"GO:0032660","Term":"regulation of interleukin-17 production","Annotated":34,"Significant":6,"Expected":2.05,"Rank in p.value_classic":817,"p.value_elim":0.01482,"p.value_classic":0.01499,"genes":"IL12A,IL15,JAK2,NOD2,OSM,SLAMF6"} {"GO.ID":"GO:0032620","Term":"interleukin-17 production","Annotated":34,"Significant":6,"Expected":2.05,"Rank in p.value_classic":818,"p.value_elim":0.01482,"p.value_classic":0.01499,"genes":"IL12A,IL15,JAK2,NOD2,OSM,SLAMF6"} {"GO.ID":"GO:0000077","Term":"DNA damage checkpoint signaling","Annotated":122,"Significant":14,"Expected":7.37,"Rank in p.value_classic":819,"p.value_elim":0.01497,"p.value_classic":0.01527,"genes":"BRCA1,CDK1,CLSPN,DTL,DTX3L,E2F1,EME1,FBXO6,GTSE1,MUC1,PARP9,PML,TICRR,WDR76"} {"GO.ID":"GO:0007249","Term":"canonical NF-kappaB signal transduction","Annotated":281,"Significant":32,"Expected":16.97,"Rank in p.value_classic":434,"p.value_elim":0.01503,"p.value_classic":0.0004,"genes":"ADAM8,APOL3,CARD16,CD40,CD74,CLEC6A,CX3CR1,EDA,EDN1,GBP7,HLA-DRB1,IFIT5,LITAF,NLRP12,NOD2,OPTN,RELB,RIPK2,S100A13,SECTM1,SLC20A1,STAT1,TANK,TICAM2,TIFA,TIFAB,TLR7,TLR8,TNFSF10,TRIM22,UBD,ZC3H12A"} {"GO.ID":"GO:0002690","Term":"positive regulation of leukocyte chemotaxis","Annotated":76,"Significant":10,"Expected":4.59,"Rank in p.value_classic":822,"p.value_elim":0.01541,"p.value_classic":0.01566,"genes":"CCL5,CCL7,CD74,CSF1,CX3CR1,CXCL10,EDN1,IL12A,SLAMF1,VEGFC"} {"GO.ID":"GO:0050792","Term":"regulation of viral process","Annotated":146,"Significant":28,"Expected":8.82,"Rank in p.value_classic":167,"p.value_elim":0.0163,"p.value_classic":4.1e-08,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CD28,CD74,CIITA,DYNLT1,FCN1,GBP7,HLA-DRB1,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,LAMP3,OAS2,OAS3,PLSCR1,RSAD2,STAT1,TOP2A,TRIM22,TRIM31,TYRO3,ZNFX1"} {"GO.ID":"GO:0046633","Term":"alpha-beta T cell proliferation","Annotated":38,"Significant":9,"Expected":2.3,"Rank in p.value_classic":422,"p.value_elim":0.0163,"p.value_classic":0.00034,"genes":"CD274,CD28,HLA-A,HLA-E,IL15,IRF1,JAK2,RIPK2,TNFRSF14"} {"GO.ID":"GO:0045639","Term":"positive regulation of myeloid cell differentiation","Annotated":88,"Significant":11,"Expected":5.31,"Rank in p.value_classic":824,"p.value_elim":0.01633,"p.value_classic":0.01661,"genes":"CD101,CD74,CSF1,FAXDC2,HLA-DRB1,KITLG,SCIN,STAT1,TAL1,TESC,TNFRSF11A"} {"GO.ID":"GO:0051928","Term":"positive regulation of calcium ion transport","Annotated":88,"Significant":11,"Expected":5.31,"Rank in p.value_classic":825,"p.value_elim":0.01633,"p.value_classic":0.01661,"genes":"ANK2,CCL5,CXCL10,CXCL11,CXCL9,F2RL3,LILRA2,P2RX4,P2RX7,SRI,TRDN"} {"GO.ID":"GO:1905818","Term":"regulation of chromosome separation","Annotated":70,"Significant":14,"Expected":4.23,"Rank in p.value_classic":345,"p.value_elim":0.01643,"p.value_classic":0.00006,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,PLSCR1,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0032653","Term":"regulation of interleukin-10 production","Annotated":52,"Significant":12,"Expected":3.14,"Rank in p.value_classic":335,"p.value_elim":0.01652,"p.value_classic":0.00005,"genes":"CD274,CD28,CD83,DLL1,HGF,HLA-DRB1,IDO1,IRF4,JAK3,NOD2,PDCD1LG2,TNFRSF21"} {"GO.ID":"GO:0032613","Term":"interleukin-10 production","Annotated":52,"Significant":12,"Expected":3.14,"Rank in p.value_classic":336,"p.value_elim":0.01652,"p.value_classic":0.00005,"genes":"CD274,CD28,CD83,DLL1,HGF,HLA-DRB1,IDO1,IRF4,JAK3,NOD2,PDCD1LG2,TNFRSF21"} {"GO.ID":"GO:0031341","Term":"regulation of cell killing","Annotated":82,"Significant":24,"Expected":4.95,"Rank in p.value_classic":101,"p.value_elim":0.01654,"p.value_classic":4.5e-11,"genes":"B2M,CD1A,CD1C,CEACAM1,CFH,CR1L,CX3CR1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,SLAMF6,STAP1,TAP2"} {"GO.ID":"GO:0044321","Term":"response to leptin","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":827,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"CCNA2,EDN1,NR4A3,PID1"} {"GO.ID":"GO:0034134","Term":"toll-like receptor 2 signaling pathway","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":828,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"ACOD1,LYN,NOD2,RIPK2"} {"GO.ID":"GO:0007413","Term":"axonal fasciculation","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":829,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"EPHB3,NRCAM,NRP1,TNFRSF21"} {"GO.ID":"GO:0106030","Term":"neuron projection fasciculation","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":830,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"EPHB3,NRCAM,NRP1,TNFRSF21"} {"GO.ID":"GO:0048535","Term":"lymph node development","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":831,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"IL15,LTA,POLB,TNFRSF11A"} {"GO.ID":"GO:1903523","Term":"negative regulation of blood circulation","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":832,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"GJD3,SPTBN4,SRI,ZC3H12A"} {"GO.ID":"GO:0046653","Term":"tetrahydrofolate metabolic process","Annotated":17,"Significant":4,"Expected":1.03,"Rank in p.value_classic":833,"p.value_elim":0.01657,"p.value_classic":0.01671,"genes":"DHFR,GCH1,MTHFD2,TYMS"} {"GO.ID":"GO:0051985","Term":"negative regulation of chromosome segregation","Annotated":47,"Significant":10,"Expected":2.84,"Rank in p.value_classic":435,"p.value_elim":0.01668,"p.value_classic":0.00041,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:1905819","Term":"negative regulation of chromosome separation","Annotated":47,"Significant":10,"Expected":2.84,"Rank in p.value_classic":436,"p.value_elim":0.01668,"p.value_classic":0.00041,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:1902100","Term":"negative regulation of metaphase/anaphase transition of cell cycle","Annotated":47,"Significant":10,"Expected":2.84,"Rank in p.value_classic":437,"p.value_elim":0.01668,"p.value_classic":0.00041,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0046928","Term":"regulation of neurotransmitter secretion","Annotated":66,"Significant":9,"Expected":3.99,"Rank in p.value_classic":835,"p.value_elim":0.0169,"p.value_classic":0.01716,"genes":"ASIC1,DTNBP1,DYSF,LRRK2,MCTP2,MYOF,STX1A,SV2B,SYT1"} {"GO.ID":"GO:0043330","Term":"response to exogenous dsRNA","Annotated":35,"Significant":6,"Expected":2.11,"Rank in p.value_classic":836,"p.value_elim":0.017,"p.value_classic":0.01719,"genes":"COLEC12,IFIH1,NOD2,RALB,RIPK2,TICAM2"} {"GO.ID":"GO:0032735","Term":"positive regulation of interleukin-12 production","Annotated":35,"Significant":6,"Expected":2.11,"Rank in p.value_classic":837,"p.value_elim":0.017,"p.value_classic":0.01719,"genes":"HLA-G,IDO1,IRF1,NOD2,RIPK2,SCIMP"} {"GO.ID":"GO:1902692","Term":"regulation of neuroblast proliferation","Annotated":35,"Significant":6,"Expected":2.11,"Rank in p.value_classic":838,"p.value_elim":0.017,"p.value_classic":0.01719,"genes":"CX3CR1,HAPLN3,LRRK2,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0042742","Term":"defense response to bacterium","Annotated":174,"Significant":30,"Expected":10.51,"Rank in p.value_classic":192,"p.value_elim":0.01718,"p.value_classic":1.6e-07,"genes":"CASP4,CASP7,COLEC12,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GSDMA,GSDMD,H2BC21,HLA-A,HLA-E,IL12A,KLRK1,LTA,NOD2,OAS2,OAS3,OPTN,P2RX7,RIPK2,RNF213,SLAMF8,SLC11A1,TNFRSF14,TNFSF8,ZNFX1"} {"GO.ID":"GO:2000045","Term":"regulation of G1/S transition of mitotic cell cycle","Annotated":149,"Significant":16,"Expected":9,"Rank in p.value_classic":841,"p.value_elim":0.01756,"p.value_classic":0.01794,"genes":"APPL2,BTN2A2,CCNE2,CDC6,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,KLF4,MUC1,PML,PSME1,PSME2,RRM2,WEE1"} {"GO.ID":"GO:0071706","Term":"tumor necrosis factor superfamily cytokine production","Annotated":149,"Significant":16,"Expected":9,"Rank in p.value_classic":842,"p.value_elim":0.01756,"p.value_classic":0.01794,"genes":"ADAM8,CD274,CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:1903555","Term":"regulation of tumor necrosis factor superfamily cytokine production","Annotated":149,"Significant":16,"Expected":9,"Rank in p.value_classic":843,"p.value_elim":0.01756,"p.value_classic":0.01794,"genes":"ADAM8,CD274,CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:1901988","Term":"negative regulation of cell cycle phase transition","Annotated":243,"Significant":38,"Expected":14.68,"Rank in p.value_classic":175,"p.value_elim":0.01765,"p.value_classic":5.7e-08,"genes":"ATF5,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CDC45,CDC6,CDK1,CDT1,CENPF,CHMP4C,CLSPN,DTL,DTX3L,E2F1,EME1,FAM107A,FBXO6,GTSE1,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PARP9,PKMYT1,PML,SPC24,SPC25,TICRR,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0097696","Term":"receptor signaling pathway via STAT","Annotated":133,"Significant":22,"Expected":8.03,"Rank in p.value_classic":301,"p.value_elim":0.01773,"p.value_classic":0.00001,"genes":"AGT,CCL5,CD40,CSF2RB,DAB1,GBP7,IL12A,IL15,IL15RA,IL22RA2,IL31RA,JAK2,JAK3,LYN,NMI,OSM,PARP14,PARP9,SOCS1,STAT1,STAT2,TNFSF18"} {"GO.ID":"GO:1902750","Term":"negative regulation of cell cycle G2/M phase transition","Annotated":66,"Significant":12,"Expected":3.99,"Rank in p.value_classic":453,"p.value_elim":0.01783,"p.value_classic":0.00052,"genes":"ATF5,AURKB,BRCA1,CDC6,CDK1,CHMP4C,CLSPN,DTL,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0009119","Term":"ribonucleoside metabolic process","Annotated":26,"Significant":5,"Expected":1.57,"Rank in p.value_classic":844,"p.value_elim":0.0179,"p.value_classic":0.01808,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4,PRTFDC1"} {"GO.ID":"GO:0033032","Term":"regulation of myeloid cell apoptotic process","Annotated":26,"Significant":5,"Expected":1.57,"Rank in p.value_classic":845,"p.value_elim":0.0179,"p.value_classic":0.01808,"genes":"CCL5,HCAR2,IRF7,KITLG,NOD2"} {"GO.ID":"GO:0002052","Term":"positive regulation of neuroblast proliferation","Annotated":26,"Significant":5,"Expected":1.57,"Rank in p.value_classic":846,"p.value_elim":0.0179,"p.value_classic":0.01808,"genes":"CX3CR1,HAPLN3,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0055078","Term":"sodium ion homeostasis","Annotated":26,"Significant":5,"Expected":1.57,"Rank in p.value_classic":847,"p.value_elim":0.0179,"p.value_classic":0.01808,"genes":"AGT,ATP1B2,EDN1,NPR1,SLC12A3"} {"GO.ID":"GO:0051588","Term":"regulation of neurotransmitter transport","Annotated":78,"Significant":10,"Expected":4.71,"Rank in p.value_classic":850,"p.value_elim":0.01825,"p.value_classic":0.01854,"genes":"ASIC1,DTNBP1,DYSF,LRRK2,MCTP2,MYOF,STX1A,SV2B,SYNGR3,SYT1"} {"GO.ID":"GO:0007204","Term":"positive regulation of cytosolic calcium ion concentration","Annotated":113,"Significant":13,"Expected":6.82,"Rank in p.value_classic":852,"p.value_elim":0.01827,"p.value_classic":0.01861,"genes":"CCRL2,CD38,CX3CR1,CXCR3,CYSLTR1,EDN1,GHRL,JAK2,P2RX4,P2RX7,PML,PROK2,PTGER4"} {"GO.ID":"GO:1903900","Term":"regulation of viral life cycle","Annotated":125,"Significant":26,"Expected":7.55,"Rank in p.value_classic":158,"p.value_elim":0.0183,"p.value_classic":2.2e-08,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CD28,CD74,CIITA,FCN1,GBP7,HLA-DRB1,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,LAMP3,OAS2,OAS3,PLSCR1,RSAD2,TOP2A,TRIM22,TRIM31,TYRO3,ZNFX1"} {"GO.ID":"GO:0032088","Term":"negative regulation of NF-kappaB transcription factor activity","Annotated":67,"Significant":9,"Expected":4.05,"Rank in p.value_classic":853,"p.value_elim":0.01852,"p.value_classic":0.0188,"genes":"ACOD1,ADORA3,AIM2,CYLD,KLF4,NLRC5,NLRP12,PARP10,ZC3H12A"} {"GO.ID":"GO:0051784","Term":"negative regulation of nuclear division","Annotated":58,"Significant":11,"Expected":3.5,"Rank in p.value_classic":460,"p.value_elim":0.01884,"p.value_classic":0.00061,"genes":"AURKB,BIRC5,BUB1B,CENPF,HORMAD1,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0045654","Term":"positive regulation of megakaryocyte differentiation","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":854,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"FAXDC2,SCIN,TESC"} {"GO.ID":"GO:0060397","Term":"growth hormone receptor signaling pathway via JAK-STAT","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":855,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"JAK2,JAK3,LYN"} {"GO.ID":"GO:0009176","Term":"pyrimidine deoxyribonucleoside monophosphate metabolic process","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":856,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"DPYS,TYMP,TYMS"} {"GO.ID":"GO:0060368","Term":"regulation of Fc receptor mediated stimulatory signaling pathway","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":857,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"APPL2,LYN,PLSCR1"} {"GO.ID":"GO:0060330","Term":"regulation of response to type II interferon","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":858,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"NLRC5,PARP14,PARP9"} {"GO.ID":"GO:0060334","Term":"regulation of type II interferon-mediated signaling pathway","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":859,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"NLRC5,PARP14,PARP9"} {"GO.ID":"GO:0002291","Term":"T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":860,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"FGL2,HLA-DMB,ICAM1"} {"GO.ID":"GO:0002713","Term":"negative regulation of B cell mediated immunity","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":861,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"BCL6,CR1L,PARP3"} {"GO.ID":"GO:0032817","Term":"regulation of natural killer cell proliferation","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":862,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"HLA-E,IL15,JAK2"} {"GO.ID":"GO:0002890","Term":"negative regulation of immunoglobulin mediated immune response","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":863,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"BCL6,CR1L,PARP3"} {"GO.ID":"GO:0031665","Term":"negative regulation of lipopolysaccharide-mediated signaling pathway","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":864,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"ACOD1,CARD16,LILRA2"} {"GO.ID":"GO:1903867","Term":"extraembryonic membrane development","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":865,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"ASCL2,E2F8,HTRA1"} {"GO.ID":"GO:0070099","Term":"regulation of chemokine-mediated signaling pathway","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":866,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"CCL5,EDN1,PADI2"} {"GO.ID":"GO:0042976","Term":"activation of Janus kinase activity","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":867,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"AGT,CCL5,JAK2"} {"GO.ID":"GO:0006568","Term":"tryptophan metabolic process","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":868,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0006586","Term":"indolalkylamine metabolic process","Annotated":10,"Significant":3,"Expected":0.6,"Rank in p.value_classic":869,"p.value_elim":0.019,"p.value_classic":0.01912,"genes":"IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0023061","Term":"signal release","Annotated":353,"Significant":38,"Expected":21.32,"Rank in p.value_classic":429,"p.value_elim":0.01901,"p.value_classic":0.00038,"genes":"ADORA3,AGT,ASIC1,CADPS2,CCL5,CD38,CRHBP,DAB2,DTNBP1,DYSF,EDN1,ERC2,EXOC3L1,GHRL,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LRRK2,LYN,MCTP2,MYOF,OSM,P2RX4,P2RX7,PRRT2,SIDT2,SLC16A10,SRI,STX11,STX1A,SUCNR1,SV2B,SYT1,SYT6,TGM2,TNFRSF11A"} {"GO.ID":"GO:0140014","Term":"mitotic nuclear division","Annotated":262,"Significant":33,"Expected":15.82,"Rank in p.value_classic":337,"p.value_elim":0.01927,"p.value_classic":0.00005,"genes":"ANLN,AURKB,BIRC5,BUB1B,CD28,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,EDN1,EML4,KIF11,KIF18B,KIF23,LRP5,MAD2L1,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,PKMYT1,PRC1,SPC24,SPC25,UHRF1,ZWINT"} {"GO.ID":"GO:0050432","Term":"catecholamine secretion","Annotated":36,"Significant":6,"Expected":2.17,"Rank in p.value_classic":872,"p.value_elim":0.01939,"p.value_classic":0.01961,"genes":"ADORA3,DTNBP1,STX1A,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0030890","Term":"positive regulation of B cell proliferation","Annotated":36,"Significant":6,"Expected":2.17,"Rank in p.value_classic":873,"p.value_elim":0.01939,"p.value_classic":0.01961,"genes":"BCL6,CD38,CD74,GPR183,IL7,TNFSF13B"} {"GO.ID":"GO:0032733","Term":"positive regulation of interleukin-10 production","Annotated":36,"Significant":6,"Expected":2.17,"Rank in p.value_classic":874,"p.value_elim":0.01939,"p.value_classic":0.01961,"genes":"CD274,CD28,CD83,HGF,IRF4,NOD2"} {"GO.ID":"GO:0002714","Term":"positive regulation of B cell mediated immunity","Annotated":36,"Significant":6,"Expected":2.17,"Rank in p.value_classic":875,"p.value_elim":0.01939,"p.value_classic":0.01961,"genes":"C3,CD28,HLA-E,LTA,NOD2,TBX21"} {"GO.ID":"GO:0002891","Term":"positive regulation of immunoglobulin mediated immune response","Annotated":36,"Significant":6,"Expected":2.17,"Rank in p.value_classic":876,"p.value_elim":0.01939,"p.value_classic":0.01961,"genes":"C3,CD28,HLA-E,LTA,NOD2,TBX21"} {"GO.ID":"GO:0002753","Term":"cytoplasmic pattern recognition receptor signaling pathway","Annotated":149,"Significant":19,"Expected":9,"Rank in p.value_classic":531,"p.value_elim":0.01952,"p.value_classic":0.0016,"genes":"AURKB,COLEC12,CYLD,DDX60,GBP2,GBP5,GRAMD4,IFIH1,IRF7,MEFV,NOD2,OAS3,RIPK2,RSAD2,SCIMP,TIFA,TLR7,TLR8,TRIM31"} {"GO.ID":"GO:0002821","Term":"positive regulation of adaptive immune response","Annotated":114,"Significant":28,"Expected":6.89,"Rank in p.value_classic":105,"p.value_elim":0.01956,"p.value_classic":1.1e-10,"genes":"B2M,C3,CD1A,CD1C,CD274,CD28,CLEC6A,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,JAK2,LTA,NOD2,P2RX7,RIPK2,RSAD2,SLAMF1,SLC11A1,TAP2,TBX21,TNFSF13B"} {"GO.ID":"GO:0071496","Term":"cellular response to external stimulus","Annotated":295,"Significant":27,"Expected":17.82,"Rank in p.value_classic":879,"p.value_elim":0.01983,"p.value_classic":0.02041,"genes":"ATF3,CASTOR1,CD40,FAM107A,FAS,GLUL,GSDMD,IRF1,KCNJ2,KIF26A,LPL,LRRK2,LYN,MAP1LC3C,P2RX7,PDK4,PIM1,PMAIP1,PTGER4,RALB,SESN3,TLR5,TLR7,TLR8,TNFRSF11A,VCAM1,ZC3H12A"} {"GO.ID":"GO:0002468","Term":"dendritic cell antigen processing and presentation","Annotated":14,"Significant":6,"Expected":0.85,"Rank in p.value_classic":359,"p.value_elim":0.01988,"p.value_classic":0.00009,"genes":"CD74,FGL2,HLA-DRA,HLA-DRB1,NOD2,SLC11A1"} {"GO.ID":"GO:0019730","Term":"antimicrobial humoral response","Annotated":53,"Significant":11,"Expected":3.2,"Rank in p.value_classic":404,"p.value_elim":0.01989,"p.value_classic":0.00027,"genes":"ACOD1,CCL13,CXCL10,CXCL11,CXCL5,CXCL9,H2BC21,HLA-A,HLA-E,NOD2,SLC11A1"} {"GO.ID":"GO:0051865","Term":"protein autoubiquitination","Annotated":68,"Significant":9,"Expected":4.11,"Rank in p.value_classic":884,"p.value_elim":0.02024,"p.value_classic":0.02054,"genes":"BRCA1,DTX3L,LRRK2,RNF141,RNF19B,RNF213,TRIM17,UBE2T,UHRF1"} {"GO.ID":"GO:0048678","Term":"response to axon injury","Annotated":68,"Significant":9,"Expected":4.11,"Rank in p.value_classic":885,"p.value_elim":0.02024,"p.value_classic":0.02054,"genes":"CDK1,DHFR,JAK2,KLF4,KREMEN1,LYN,P2RX4,RTN4RL1,SCARF1"} {"GO.ID":"GO:0006887","Term":"exocytosis","Annotated":288,"Significant":30,"Expected":17.39,"Rank in p.value_classic":565,"p.value_elim":0.0203,"p.value_classic":0.00249,"genes":"ATP13A2,CADPS2,CCL5,CCL8,CEACAM1,CRHBP,DTNBP1,ERC2,EXOC3L1,EXOC3L4,HLA-F,ITSN1,LRRK2,LYN,NR4A3,P2RX7,PLEK,PRRT2,RALB,S100A10,S100A13,SCIN,SEPTIN4,STX11,STX1A,SV2B,SYNGR3,SYT1,SYT6,TNFAIP2"} {"GO.ID":"GO:0007076","Term":"mitotic chromosome condensation","Annotated":18,"Significant":4,"Expected":1.09,"Rank in p.value_classic":880,"p.value_elim":0.02031,"p.value_classic":0.02048,"genes":"CDCA5,NCAPG,NCAPH,NUSAP1"} {"GO.ID":"GO:2000319","Term":"regulation of T-helper 17 cell differentiation","Annotated":18,"Significant":4,"Expected":1.09,"Rank in p.value_classic":881,"p.value_elim":0.02031,"p.value_classic":0.02048,"genes":"ASCL2,IL12RB1,TBX21,ZC3H12A"} {"GO.ID":"GO:0045091","Term":"regulation of single stranded viral RNA replication via double stranded DNA intermediate","Annotated":18,"Significant":4,"Expected":1.09,"Rank in p.value_classic":882,"p.value_elim":0.02031,"p.value_classic":0.02048,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,TOP2A"} {"GO.ID":"GO:0051303","Term":"establishment of chromosome localization","Annotated":103,"Significant":12,"Expected":6.22,"Rank in p.value_classic":890,"p.value_elim":0.02085,"p.value_classic":0.02122,"genes":"AURKB,BIRC5,CDCA5,CDT1,CENPF,CHMP4C,EML4,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0010948","Term":"negative regulation of cell cycle process","Annotated":281,"Significant":42,"Expected":16.97,"Rank in p.value_classic":169,"p.value_elim":0.02088,"p.value_classic":4.3e-08,"genes":"ATF5,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNF,CDC45,CDC6,CDK1,CDT1,CENPF,CHMP4C,CLSPN,DTL,DTX3L,E2F1,E2F8,EME1,FAM107A,FBXO6,GTSE1,HLA-G,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PARP9,PKMYT1,PML,SPC24,SPC25,TICRR,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0010742","Term":"macrophage derived foam cell differentiation","Annotated":27,"Significant":5,"Expected":1.63,"Rank in p.value_classic":887,"p.value_elim":0.02091,"p.value_classic":0.02112,"genes":"AGT,CSF1,LPL,SOAT1,STAT1"} {"GO.ID":"GO:0034121","Term":"regulation of toll-like receptor signaling pathway","Annotated":27,"Significant":5,"Expected":1.63,"Rank in p.value_classic":888,"p.value_elim":0.02091,"p.value_classic":0.02112,"genes":"CD300LF,IRF1,IRF4,IRF7,TYRO3"} {"GO.ID":"GO:0035590","Term":"purinergic nucleotide receptor signaling pathway","Annotated":27,"Significant":5,"Expected":1.63,"Rank in p.value_classic":889,"p.value_elim":0.02091,"p.value_classic":0.02112,"genes":"ADORA3,NECAB2,P2RX4,P2RX7,P2RY14"} {"GO.ID":"GO:0051716","Term":"cellular response to stimulus","Annotated":5564,"Significant":446,"Expected":336.04,"Rank in p.value_classic":42,"p.value_elim":0.02092,"p.value_classic":3.6e-16,"genes":"ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AKAP7,AMER1,AMOT,ANK2,APOL3,APPL2,ARAP2,ARMT1,ASB2,ASIC1,ATF3,ATP13A2,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C3,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CBR3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD69,CD7,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CHAC1,CHAF1B,CHMP4C,CHRD,CIBAR1,CISH,CLEC6A,CLSPN,CMPK2,COLEC12,COMP,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DMC1,DTL,DTNBP1,DTX3L,DYNLT1,E2F1,E2F2,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,EPAS1,EPHB3,EPHX1,ESCO2,EXO1,F2RL3,FAM107A,FAM13A,FANCE,FAS,FBXO6,FCN1,FEN1,FGD5,FLT3LG,FSTL4,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GFRA2,GHRL,GINS2,GLDN,GLIPR2,GLUL,GNG2,GPR183,GPR31,GRAMD1B,GRAMD4,GRIN3A,GRM8,GSDMD,GSTK1,GTPBP1,GTSE1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,HORMAD1,HRH2,HSBP1L1,HSD3B7,HSH2D,HTRA1,ICAM1,IFI27,IFI35,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JAK2,JAK3,KARS1,KCNJ10,KCNJ2,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MAD2L1,MAF,MAML3,MAP1LC3C,MCF2L,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MEFV,MERTK,MIR503,MMP9,MRAS,MT2A,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYOZ2,NCF1,NDC80,NECAB2,NEIL3,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRGN,NRK,NRP1,NUCB1,NUF2,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,ONECUT2,OPTN,OR2I1P,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PARP3,PARP9,PCLAF,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PKD1L3,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POLB,POLE2,PPM1E,PROK2,PTGER4,PTPRU,PXN,PYHIN1,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGEF1C,RASGRF1,RECQL4,RELB,REPS2,RGS18,RHEBL1,RIPK2,RMI2,RNF213,RSAD2,RSU1,RTN4RL1,RUFY4,RXFP1,S100A13,S1PR1,SBNO2,SCARF1,SCIMP,SECTM1,SEMA6B,SEPTIN4,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF8,SLC11A1,SLC12A3,SLC20A1,SLC2A5,SNX10,SOCS1,SOX17,SPC24,SPC25,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SUCNR1,SYNE1,SYT1,SYT6,TAGAP,TANK,TBX21,TESC,TFEC,TGM2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TONSL,TOP2A,TPCN1,TRABD2A,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYRO3,UBD,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VRK2,WDR76,WWP1,XRCC2,XRN1,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0002752","Term":"cell surface pattern recognition receptor signaling pathway","Annotated":63,"Significant":12,"Expected":3.8,"Rank in p.value_classic":421,"p.value_elim":0.02146,"p.value_classic":0.00033,"genes":"ACOD1,APPL2,FCN1,IFI35,LILRA2,LYN,NMI,NOD2,RIPK2,SCIMP,TICAM2,TLR5"} {"GO.ID":"GO:2001238","Term":"positive regulation of extrinsic apoptotic signaling pathway","Annotated":47,"Significant":7,"Expected":2.84,"Rank in p.value_classic":891,"p.value_elim":0.02146,"p.value_classic":0.02173,"genes":"AGT,ATF3,CYLD,G0S2,PMAIP1,PML,TNFSF10"} {"GO.ID":"GO:0032655","Term":"regulation of interleukin-12 production","Annotated":54,"Significant":11,"Expected":3.26,"Rank in p.value_classic":417,"p.value_elim":0.02151,"p.value_classic":0.00032,"genes":"HLA-B,HLA-G,IDO1,IRF1,JAK3,MEFV,NOD2,RIPK2,SCIMP,SLAMF1,TLR8"} {"GO.ID":"GO:0032615","Term":"interleukin-12 production","Annotated":54,"Significant":11,"Expected":3.26,"Rank in p.value_classic":418,"p.value_elim":0.02151,"p.value_classic":0.00032,"genes":"HLA-B,HLA-G,IDO1,IRF1,JAK3,MEFV,NOD2,RIPK2,SCIMP,SLAMF1,TLR8"} {"GO.ID":"GO:0050798","Term":"activated T cell proliferation","Annotated":37,"Significant":6,"Expected":2.23,"Rank in p.value_classic":893,"p.value_elim":0.022,"p.value_classic":0.02224,"genes":"BTN2A2,BTN3A1,CD274,IL12RB1,PDCD1LG2,SLAMF1"} {"GO.ID":"GO:2000403","Term":"positive regulation of lymphocyte migration","Annotated":37,"Significant":6,"Expected":2.23,"Rank in p.value_classic":894,"p.value_elim":0.022,"p.value_classic":0.02224,"genes":"ADAM8,ASCL2,CCL5,CCL7,CXCL10,TNFRSF14"} {"GO.ID":"GO:0002460","Term":"adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":261,"Significant":60,"Expected":15.76,"Rank in p.value_classic":21,"p.value_elim":0.02209,"p.value_classic":6.6e-20,"genes":"ASCL2,B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD274,CD28,CD40,CD74,CD80,CEACAM1,CLEC6A,CR1L,CSF2RB,EXO1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL18BP,IL27,IL4I1,IRF4,IRF7,JAK2,JAK3,LTA,NOD2,P2RX7,PARP3,RELB,RIPK2,RSAD2,SERPING1,SLAMF1,SLAMF6,SLC11A1,TAP2,TBX21,TLR8,TNFSF13B,UNG,ZC3H12A"} {"GO.ID":"GO:0007080","Term":"mitotic metaphase chromosome alignment","Annotated":58,"Significant":8,"Expected":3.5,"Rank in p.value_classic":896,"p.value_elim":0.02219,"p.value_classic":0.02249,"genes":"AURKB,BIRC5,CDCA5,CDT1,CHMP4C,EML4,NDC80,NUF2"} {"GO.ID":"GO:0044843","Term":"cell cycle G1/S phase transition","Annotated":218,"Significant":21,"Expected":13.17,"Rank in p.value_classic":897,"p.value_elim":0.02256,"p.value_classic":0.02312,"genes":"APPL2,BTN2A2,CCNA2,CCNE2,CDC25A,CDC6,CDK1,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,IQGAP3,KLF4,MIR503,MUC1,PML,PSME1,PSME2,RRM2,WEE1"} {"GO.ID":"GO:1902106","Term":"negative regulation of leukocyte differentiation","Annotated":87,"Significant":18,"Expected":5.25,"Rank in p.value_classic":261,"p.value_elim":0.02262,"p.value_classic":3.5e-06,"genes":"ASCL2,BCL6,CD74,CEACAM1,CTLA4,FGL2,HLA-G,IRF1,JAK3,LAG3,LILRB3,LYN,SOCS1,TBX21,TMEM176A,TMEM176B,TNFAIP6,ZC3H12A"} {"GO.ID":"GO:0070227","Term":"lymphocyte apoptotic process","Annotated":73,"Significant":17,"Expected":4.41,"Rank in p.value_classic":227,"p.value_elim":0.02264,"p.value_classic":1.1e-06,"genes":"ADAM8,AURKB,BCL2L11,BCL6,CASP7,CCL5,CD274,CD74,EBF4,FAS,GIMAP8,IDO1,JAK3,LYN,P2RX7,PDCD1,TNFRSF21"} {"GO.ID":"GO:0002221","Term":"pattern recognition receptor signaling pathway","Annotated":224,"Significant":36,"Expected":13.53,"Rank in p.value_classic":176,"p.value_elim":0.02355,"p.value_classic":6.3e-08,"genes":"ACOD1,AIM2,APPL2,AURKB,CD274,CD300LF,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,IFI35,IFIH1,IRF1,IRF4,IRF7,LILRA2,LYN,MEFV,NMI,NOD2,OAS3,RIPK2,RSAD2,SCIMP,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRIM31,TYRO3"} {"GO.ID":"GO:0051099","Term":"positive regulation of binding","Annotated":105,"Significant":12,"Expected":6.34,"Rank in p.value_classic":902,"p.value_elim":0.02388,"p.value_classic":0.0243,"genes":"B2M,CDT1,DTX3L,LRRK2,MMP9,NRP1,PARP9,PYHIN1,RALB,RAPGEF2,RIPK2,STMN1"} {"GO.ID":"GO:0010952","Term":"positive regulation of peptidase activity","Annotated":142,"Significant":15,"Expected":8.58,"Rank in p.value_classic":910,"p.value_elim":0.02402,"p.value_classic":0.0245,"genes":"AIM2,CTSL,CTSS,FAS,GRAMD4,JAK2,LYN,MEFV,NLRP12,PMAIP1,PSME1,PSME2,RIPK2,TANK,TNFSF10"} {"GO.ID":"GO:0002532","Term":"production of molecular mediator involved in inflammatory response","Annotated":70,"Significant":9,"Expected":4.23,"Rank in p.value_classic":903,"p.value_elim":0.02404,"p.value_classic":0.02439,"genes":"APPL2,GBP5,LYN,MEFV,NCF1,NOD2,SLAMF8,TICAM2,ZC3H12A"} {"GO.ID":"GO:0046209","Term":"nitric oxide metabolic process","Annotated":70,"Significant":9,"Expected":4.23,"Rank in p.value_classic":904,"p.value_elim":0.02404,"p.value_classic":0.02439,"genes":"CX3CR1,CYP1A1,EDN1,GCH1,JAK2,KLF4,KLRK1,P2RX4,ZC3H12A"} {"GO.ID":"GO:0002833","Term":"positive regulation of response to biotic stimulus","Annotated":323,"Significant":53,"Expected":19.51,"Rank in p.value_classic":92,"p.value_elim":0.02423,"p.value_classic":2.1e-11,"genes":"ACOD1,ADAM8,AIM2,APPL2,AURKB,CCL5,CD274,CD300LF,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,HLA-DRB1,HLA-E,HLA-F,HLA-G,IFI35,IFIH1,IL12A,IRF1,IRF4,IRF7,KLRK1,LAG3,LILRA2,LYN,MEFV,NLRC5,NMI,NOD2,OAS3,PARP9,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SLAMF6,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRIM31,TYRO3,ZBP1,ZNFX1"} {"GO.ID":"GO:0086004","Term":"regulation of cardiac muscle cell contraction","Annotated":28,"Significant":5,"Expected":1.69,"Rank in p.value_classic":905,"p.value_elim":0.02423,"p.value_classic":0.02447,"genes":"ANK2,CAMK2D,KCNJ2,PDE4B,SRI"} {"GO.ID":"GO:1990573","Term":"potassium ion import across plasma membrane","Annotated":28,"Significant":5,"Expected":1.69,"Rank in p.value_classic":906,"p.value_elim":0.02423,"p.value_classic":0.02447,"genes":"ATP1B2,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"GO.ID":"GO:0032673","Term":"regulation of interleukin-4 production","Annotated":28,"Significant":5,"Expected":1.69,"Rank in p.value_classic":907,"p.value_elim":0.02423,"p.value_classic":0.02447,"genes":"CD28,CD83,HLA-DRB1,HLA-E,IRF4"} {"GO.ID":"GO:0032633","Term":"interleukin-4 production","Annotated":28,"Significant":5,"Expected":1.69,"Rank in p.value_classic":908,"p.value_elim":0.02423,"p.value_classic":0.02447,"genes":"CD28,CD83,HLA-DRB1,HLA-E,IRF4"} {"GO.ID":"GO:0090077","Term":"foam cell differentiation","Annotated":28,"Significant":5,"Expected":1.69,"Rank in p.value_classic":909,"p.value_elim":0.02423,"p.value_classic":0.02447,"genes":"AGT,CSF1,LPL,SOAT1,STAT1"} {"GO.ID":"GO:0002455","Term":"humoral immune response mediated by circulating immunoglobulin","Annotated":34,"Significant":13,"Expected":2.05,"Rank in p.value_classic":166,"p.value_elim":0.02426,"p.value_classic":3.7e-08,"genes":"C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CR1L,EXO1,LTA,NOD2,SERPING1"} {"GO.ID":"GO:0098586","Term":"cellular response to virus","Annotated":59,"Significant":8,"Expected":3.56,"Rank in p.value_classic":912,"p.value_elim":0.02437,"p.value_classic":0.02469,"genes":"CCL5,CXCL10,IFIH1,IL12A,JAK2,TLR7,VWCE,ZC3H12A"} {"GO.ID":"GO:0046632","Term":"alpha-beta T cell differentiation","Annotated":109,"Significant":23,"Expected":6.58,"Rank in p.value_classic":180,"p.value_elim":0.0245,"p.value_classic":1.1e-07,"genes":"ASCL2,BCL6,CD80,CD83,CTSL,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF1,IRF4,ITK,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFSF8,ZC3H12A"} {"GO.ID":"GO:0010447","Term":"response to acidic pH","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":913,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"ASIC1,CTSS,GPR31,PKD1L3"} {"GO.ID":"GO:0009164","Term":"nucleoside catabolic process","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":914,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4"} {"GO.ID":"GO:0010818","Term":"T cell chemotaxis","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":915,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"CCL5,CXCL10,CXCL11,GPR183"} {"GO.ID":"GO:0039692","Term":"single stranded viral RNA replication via double stranded DNA intermediate","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":916,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,TOP2A"} {"GO.ID":"GO:0010526","Term":"retrotransposon silencing","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":917,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"APOBEC3A,APOBEC3G,PIWIL4,TDRD9"} {"GO.ID":"GO:0031338","Term":"regulation of vesicle fusion","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":918,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"ERC2,PRRT2,SLAMF1,SYT1"} {"GO.ID":"GO:0051446","Term":"positive regulation of meiotic cell cycle","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":919,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"CDC25A,DAZL,NPM2,OVOL1"} {"GO.ID":"GO:0002888","Term":"positive regulation of myeloid leukocyte mediated immunity","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":920,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"C3,HLA-E,STAP1,TICAM2"} {"GO.ID":"GO:0032528","Term":"microvillus organization","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":921,"p.value_elim":0.02452,"p.value_classic":0.02473,"genes":"ATP8B1,FSCN1,GLDN,RAPGEF2"} {"GO.ID":"GO:1903670","Term":"regulation of sprouting angiogenesis","Annotated":38,"Significant":6,"Expected":2.3,"Rank in p.value_classic":926,"p.value_elim":0.02483,"p.value_classic":0.02511,"genes":"CEACAM1,DLL1,E2F2,GHRL,GLUL,KLF4"} {"GO.ID":"GO:0071407","Term":"cellular response to organic cyclic compound","Annotated":426,"Significant":36,"Expected":25.73,"Rank in p.value_classic":948,"p.value_elim":0.02492,"p.value_classic":0.02577,"genes":"ACOD1,BCL2L11,BRCA1,CASP7,CCNA2,CDK1,COLEC12,CRHBP,CYP1A1,DAB2,DTNBP1,EDN1,FAM107A,GNG2,GRAMD1B,IFIH1,JAK2,KLF4,LBH,LRRK2,NCF1,NOD2,NR4A3,P2RX4,P2RX7,PADI2,PAQR8,PIM1,PNPLA3,RALB,RAPGEF2,SSTR2,STAT1,TGM2,XRN1,ZC3H12A"} {"GO.ID":"GO:0035666","Term":"TRIF-dependent toll-like receptor signaling pathway","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":928,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"CD274,CD300LF,TICAM2"} {"GO.ID":"GO:0010744","Term":"positive regulation of macrophage derived foam cell differentiation","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":929,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"AGT,CSF1,LPL"} {"GO.ID":"GO:0070213","Term":"protein auto-ADP-ribosylation","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":930,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"PARP10,PARP12,PARP3"} {"GO.ID":"GO:0010522","Term":"regulation of calcium ion transport into cytosol","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":931,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"P2RX4,P2RX7,PML"} {"GO.ID":"GO:0034154","Term":"toll-like receptor 7 signaling pathway","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":932,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"RSAD2,SCIMP,TLR7"} {"GO.ID":"GO:2000343","Term":"positive regulation of chemokine (C-X-C motif) ligand 2 production","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":933,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"CD74,LPL,MCOLN2"} {"GO.ID":"GO:0046007","Term":"negative regulation of activated T cell proliferation","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":934,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"BTN2A2,CD274,PDCD1LG2"} {"GO.ID":"GO:0060623","Term":"regulation of chromosome condensation","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":935,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"NCAPG,NCAPG2,NCAPH"} {"GO.ID":"GO:0071350","Term":"cellular response to interleukin-15","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":936,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"IL15,IL15RA,JAK3"} {"GO.ID":"GO:0002732","Term":"positive regulation of dendritic cell cytokine production","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":937,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"NOD2,SCIMP,TICAM2"} {"GO.ID":"GO:0002836","Term":"positive regulation of response to tumor cell","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":938,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"CD274,HLA-DRB1,IL12A"} {"GO.ID":"GO:0002839","Term":"positive regulation of immune response to tumor cell","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":939,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"CD274,HLA-DRB1,IL12A"} {"GO.ID":"GO:0046135","Term":"pyrimidine nucleoside catabolic process","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":940,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0045161","Term":"neuronal ion channel clustering","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":941,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"GLDN,NRCAM,SPTBN4"} {"GO.ID":"GO:0002664","Term":"regulation of T cell tolerance induction","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":942,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"HLA-B,HLA-G,IDO1"} {"GO.ID":"GO:0035723","Term":"interleukin-15-mediated signaling pathway","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":943,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"IL15,IL15RA,JAK3"} {"GO.ID":"GO:0035561","Term":"regulation of chromatin binding","Annotated":11,"Significant":3,"Expected":0.66,"Rank in p.value_classic":944,"p.value_elim":0.02497,"p.value_classic":0.02514,"genes":"CDT1,DTX3L,PARP9"} {"GO.ID":"GO:1903530","Term":"regulation of secretion by cell","Annotated":425,"Significant":39,"Expected":25.67,"Rank in p.value_classic":680,"p.value_elim":0.02518,"p.value_classic":0.00593,"genes":"ADAM8,ADORA3,AGT,ASIC1,ATP13A2,CADPS2,CCL5,CD38,CEACAM1,CRHBP,DAB2,DTNBP1,DYSF,EDN1,GHRL,HCAR2,HLA-DRB1,HLA-F,IL12A,JAK2,LRP5,LRRK2,LYN,MCTP2,MYOF,OSM,P2RX4,P2RX7,RSAD2,S100A10,SEPTIN4,SIDT2,SRI,STX1A,SV2B,SYT1,SYT6,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0043085","Term":"positive regulation of catalytic activity","Annotated":744,"Significant":58,"Expected":44.93,"Rank in p.value_classic":952,"p.value_elim":0.0252,"p.value_classic":0.02633,"genes":"ADORA3,AGT,AIM2,AURKB,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CHTF18,CLSPN,CSF1,CTSL,CTSS,DHFR,DSCC1,EDN1,FAS,GCH1,GRAMD4,HLA-DRB1,ITK,JAK2,KLF4,LRRK2,LYN,MEFV,MERTK,MMD,NCF1,NLRP12,PKIB,PLAAT4,PLEK,PLSCR1,PMAIP1,PSME1,PSME2,RALB,RAPGEF2,RASGEF1C,RASGRF1,RIPK2,RSU1,RXFP1,S100A10,SERINC5,SLC11A1,TANK,TGM2,TNFRSF11A,TNFSF10,TYRO3,UHRF1,USP6NL"} {"GO.ID":"GO:0043393","Term":"regulation of protein binding","Annotated":118,"Significant":13,"Expected":7.13,"Rank in p.value_classic":946,"p.value_elim":0.02521,"p.value_classic":0.02567,"genes":"AURKB,B2M,CARD16,DAB2,DTX3L,IFIT2,LRRK2,MMP9,NRP1,RALB,RAPGEF2,RIPK2,XIRP1"} {"GO.ID":"GO:1903169","Term":"regulation of calcium ion transmembrane transport","Annotated":118,"Significant":13,"Expected":7.13,"Rank in p.value_classic":947,"p.value_elim":0.02521,"p.value_classic":0.02567,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX4,P2RX7,PDE4B,PML,SRI,TRDN"} {"GO.ID":"GO:0007189","Term":"adenylate cyclase-activating G protein-coupled receptor signaling pathway","Annotated":94,"Significant":11,"Expected":5.68,"Rank in p.value_classic":950,"p.value_elim":0.0255,"p.value_classic":0.02592,"genes":"ADGRE5,ADGRG5,CXCL10,CXCL11,CXCL9,GNG2,PDE4B,PTGER4,RAPGEF2,RXFP1,S1PR1"} {"GO.ID":"GO:0016064","Term":"immunoglobulin mediated immune response","Annotated":106,"Significant":23,"Expected":6.4,"Rank in p.value_classic":177,"p.value_elim":0.02597,"p.value_classic":6.3e-08,"genes":"BCL6,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD28,CD74,CR1L,CSF2RB,EXO1,HLA-E,IRF7,LTA,NOD2,PARP3,SERPING1,TBX21,TLR8,UNG"} {"GO.ID":"GO:0008284","Term":"positive regulation of cell population proliferation","Annotated":749,"Significant":74,"Expected":45.24,"Rank in p.value_classic":306,"p.value_elim":0.02603,"p.value_classic":0.00002,"genes":"AGT,ATF3,BCL6,BIRC5,CCL5,CCNA2,CD274,CD28,CD38,CD74,CD80,CDC6,CDK1,CHRD,COMP,CSF1,CSF2RB,CX3CR1,CXCL10,CXCL5,CYSLTR1,DLL1,E2F1,EDN1,FLT3LG,GAREM1,GHRL,GPR183,HAPLN3,HBEGF,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12A,IL12RB1,IL12RB2,IL15,IL31RA,IL7,IQGAP3,JAK2,KITLG,LBH,LRP5,LTA,LYN,MARCKSL1,MIR503,MMP9,NOD2,NR4A3,NRP1,OSM,PDCD1LG2,PID1,PIM1,PML,PRC1,RIPK2,S100A13,S1PR1,SLAMF1,SSBP3,STAT1,SYNE1,TMEM119,TNFRSF11A,TNFSF13B,VCAM1,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:2001057","Term":"reactive nitrogen species metabolic process","Annotated":71,"Significant":9,"Expected":4.29,"Rank in p.value_classic":953,"p.value_elim":0.02611,"p.value_classic":0.02649,"genes":"CX3CR1,CYP1A1,EDN1,GCH1,JAK2,KLF4,KLRK1,P2RX4,ZC3H12A"} {"GO.ID":"GO:0034113","Term":"heterotypic cell-cell adhesion","Annotated":49,"Significant":7,"Expected":2.96,"Rank in p.value_classic":954,"p.value_elim":0.02645,"p.value_classic":0.02677,"genes":"CXADR,GLDN,IL1RN,ITGA7,KLF4,NRCAM,VCAM1"} {"GO.ID":"GO:0045428","Term":"regulation of nitric oxide biosynthetic process","Annotated":49,"Significant":7,"Expected":2.96,"Rank in p.value_classic":955,"p.value_elim":0.02645,"p.value_classic":0.02677,"genes":"CX3CR1,EDN1,JAK2,KLF4,KLRK1,P2RX4,ZC3H12A"} {"GO.ID":"GO:0035825","Term":"homologous recombination","Annotated":49,"Significant":7,"Expected":2.96,"Rank in p.value_classic":956,"p.value_elim":0.02645,"p.value_classic":0.02677,"genes":"BRCA1,DMC1,EME1,RAD54B,RAD54L,TOP2A,UHRF1"} {"GO.ID":"GO:0042093","Term":"T-helper cell differentiation","Annotated":68,"Significant":16,"Expected":4.11,"Rank in p.value_classic":248,"p.value_elim":0.02673,"p.value_classic":2e-06,"genes":"ASCL2,BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0051338","Term":"regulation of transferase activity","Annotated":557,"Significant":45,"Expected":33.64,"Rank in p.value_classic":958,"p.value_elim":0.02683,"p.value_classic":0.02786,"genes":"AGT,AURKB,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CEACAM1,CHTF18,CLSPN,CSF1,DEPTOR,DSCC1,DTNBP1,DTX3L,EDN1,HLA-DRB1,JAK2,KLF4,LRP5,LRRK2,LYN,MAD2L1,MERTK,MMD,MVP,NCF1,NLRC5,PARP3,PKIB,PKMYT1,PLAAT4,PPM1E,RALB,RAPGEF2,SERINC5,SLAMF8,SLC11A1,TNFRSF11A,TYRO3,WARS1"} {"GO.ID":"GO:1902806","Term":"regulation of cell cycle G1/S phase transition","Annotated":170,"Significant":17,"Expected":10.27,"Rank in p.value_classic":959,"p.value_elim":0.02747,"p.value_classic":0.02806,"genes":"APPL2,BTN2A2,CCNE2,CDC6,CDKN2C,CYP1A1,E2F1,FAM107A,GTSE1,KLF4,MIR503,MUC1,PML,PSME1,PSME2,RRM2,WEE1"} {"GO.ID":"GO:0010212","Term":"response to ionizing radiation","Annotated":132,"Significant":14,"Expected":7.97,"Rank in p.value_classic":964,"p.value_elim":0.02773,"p.value_classic":0.02825,"genes":"BRCA1,CCL7,CXCL10,KARS1,PML,POLB,RAD54B,RAD54L,TANK,THBD,TICRR,TMEM109,VCAM1,XRCC2"} {"GO.ID":"GO:0007435","Term":"salivary gland morphogenesis","Annotated":29,"Significant":5,"Expected":1.75,"Rank in p.value_classic":960,"p.value_elim":0.02788,"p.value_classic":0.02814,"genes":"EDA,HGF,NRP1,POLB,TGM2"} {"GO.ID":"GO:2000106","Term":"regulation of leukocyte apoptotic process","Annotated":80,"Significant":19,"Expected":4.83,"Rank in p.value_classic":196,"p.value_elim":0.02789,"p.value_classic":1.9e-07,"genes":"ADAM8,AURKB,BCL2L11,BCL6,CCL5,CD274,CD74,GIMAP8,HCAR2,IDO1,IRF7,JAK3,KITLG,LYN,MERTK,NOD2,P2RX7,PDCD1,RAPGEF2"} {"GO.ID":"GO:0042551","Term":"neuron maturation","Annotated":39,"Significant":6,"Expected":2.36,"Rank in p.value_classic":961,"p.value_elim":0.0279,"p.value_classic":0.02821,"genes":"C3,GLDN,LRRK2,NRCAM,SCARF1,SPTBN4"} {"GO.ID":"GO:0010564","Term":"regulation of cell cycle process","Annotated":647,"Significant":71,"Expected":39.08,"Rank in p.value_classic":216,"p.value_elim":0.02799,"p.value_classic":5.9e-07,"genes":"ANLN,APPL2,ATF5,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CHMP4C,CLSPN,CYP1A1,DAZL,DTL,DTX3L,E2F1,E2F8,EDN1,EME1,FAM107A,FBXO6,FEN1,GTSE1,HLA-G,HORMAD1,KIF11,KIF23,KLF4,LRP5,MAD2L1,MIR503,MKI67,MUC1,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,ORC1,OVOL1,PARP3,PARP9,PKMYT1,PLSCR1,PML,PRC1,PSME1,PSME2,RMI2,RRM2,SPC24,SPC25,TICRR,UBD,WDR62,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0042325","Term":"regulation of phosphorylation","Annotated":833,"Significant":79,"Expected":50.31,"Rank in p.value_classic":330,"p.value_elim":0.02839,"p.value_classic":0.00003,"genes":"AGT,BANK1,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PID1,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,RIPK2,SLAMF8,SLC11A1,SOCS1,SPTBN4,STAP1,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0045622","Term":"regulation of T-helper cell differentiation","Annotated":39,"Significant":12,"Expected":2.36,"Rank in p.value_classic":244,"p.value_elim":0.02842,"p.value_classic":1.9e-06,"genes":"ASCL2,BCL6,CD80,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,RIPK2,TBX21,ZC3H12A"} {"GO.ID":"GO:0055080","Term":"monoatomic cation homeostasis","Annotated":458,"Significant":46,"Expected":27.66,"Rank in p.value_classic":446,"p.value_elim":0.0287,"p.value_classic":0.00046,"genes":"AGT,ANK2,ANKH,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,EPAS1,ERC2,F2RL3,FAM20A,KCNJ10,KCNJ2,LRRK2,LYN,MT2A,NPR1,OCA2,P2RX7,PDK4,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC12A3,SLC31A2,SLC4A7,SNX10,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0032722","Term":"positive regulation of chemokine production","Annotated":61,"Significant":8,"Expected":3.68,"Rank in p.value_classic":971,"p.value_elim":0.02915,"p.value_classic":0.02954,"genes":"CD74,IL7,LPL,MCOLN2,NOD2,OAS3,RIPK2,TLR7"} {"GO.ID":"GO:0060612","Term":"adipose tissue development","Annotated":50,"Significant":7,"Expected":3.02,"Rank in p.value_classic":972,"p.value_elim":0.02921,"p.value_classic":0.02957,"genes":"AMER1,CSF1,DGAT2,GHRL,LPL,LRP5,PLAAT3"} {"GO.ID":"GO:0009162","Term":"deoxyribonucleoside monophosphate metabolic process","Annotated":20,"Significant":4,"Expected":1.21,"Rank in p.value_classic":966,"p.value_elim":0.02923,"p.value_classic":0.02947,"genes":"DPYS,TK1,TYMP,TYMS"} {"GO.ID":"GO:0010880","Term":"regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","Annotated":20,"Significant":4,"Expected":1.21,"Rank in p.value_classic":967,"p.value_elim":0.02923,"p.value_classic":0.02947,"genes":"ANK2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0086064","Term":"cell communication by electrical coupling involved in cardiac conduction","Annotated":20,"Significant":4,"Expected":1.21,"Rank in p.value_classic":968,"p.value_elim":0.02923,"p.value_classic":0.02947,"genes":"ATP1B2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0002295","Term":"T-helper cell lineage commitment","Annotated":20,"Significant":4,"Expected":1.21,"Rank in p.value_classic":969,"p.value_elim":0.02923,"p.value_classic":0.02947,"genes":"IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0001780","Term":"neutrophil homeostasis","Annotated":20,"Significant":4,"Expected":1.21,"Rank in p.value_classic":970,"p.value_elim":0.02923,"p.value_classic":0.02947,"genes":"CSF1,HCAR2,MERTK,PDE4B"} {"GO.ID":"GO:1903557","Term":"positive regulation of tumor necrosis factor superfamily cytokine production","Annotated":96,"Significant":11,"Expected":5.8,"Rank in p.value_classic":975,"p.value_elim":0.02926,"p.value_classic":0.02974,"genes":"ADAM8,HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2"} {"GO.ID":"GO:0050896","Term":"response to stimulus","Annotated":6487,"Significant":537,"Expected":391.79,"Rank in p.value_classic":17,"p.value_elim":0.03017,"p.value_classic":4.1e-27,"genes":"ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AKAP7,ALAS1,AMER1,AMOT,ANK2,ANKH,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APPL2,ARAP2,ARMT1,ASB2,ASCL2,ASIC1,ATF3,ATP13A2,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CBR3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD163,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD69,CD7,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHRD,CIBAR1,CIITA,CISH,CLEC10A,CLEC6A,CLIC5,CLSPN,CMPK2,COLEC12,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DMC1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,ERAP2,ESCO2,EXO1,F2RL3,FAM107A,FAM13A,FAM20A,FANCE,FAS,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FSTL4,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GFRA2,GGT5,GHRL,GINS2,GJD3,GLDN,GLIPR2,GLUL,GNG2,GPR183,GPR31,GRAMD1B,GRAMD4,GRIN3A,GRM8,GSDMA,GSDMD,GSTK1,GTPBP1,GTSE1,H2BC21,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSD3B7,HSH2D,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ISG20,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JAK2,JAK3,KARS1,KCNJ10,KCNJ2,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMP3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LY75,LYN,LYVE1,MAD2L1,MAF,MAML3,MAP1LC3C,MCF2L,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MEFV,MERTK,MIR503,MMP25,MMP9,MRAS,MSRB1,MT2A,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYOF,MYOZ2,NCF1,NDC80,NECAB2,NEIL3,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRGN,NRK,NRP1,NUB1,NUCB1,NUF2,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,ONECUT2,OPTN,OR2I1P,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PARP3,PARP9,PCLAF,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PKD1L3,PLAAT3,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POLB,POLE2,PPM1E,PROK2,PSMB10,PTGER4,PTPRU,PXN,PYHIN1,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGEF1C,RASGRF1,RECQL4,RELB,REPS2,RGS18,RHEBL1,RIPK2,RMI2,RNF19B,RNF213,RSAD2,RSU1,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SBNO2,SCARF1,SCIMP,SCO2,SECTM1,SELENOP,SELL,SEMA6B,SEPTIN4,SERINC5,SERPING1,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SLC20A1,SLC2A5,SLC4A7,SNX10,SOCS1,SOX17,SP140,SPC24,SPC25,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SUCNR1,SYNE1,SYT1,SYT6,TAGAP,TANK,TAP1,TAP2,TBX21,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM255A,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TONSL,TOP2A,TPCN1,TRABD2A,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,USP53,VCAM1,VEGFC,VRK2,VWCE,WDR76,WWP1,XAF1,XRCC2,XRN1,ZBP1,ZC3H12A,ZNFX1,ZWINT"} {"GO.ID":"GO:0000819","Term":"sister chromatid segregation","Annotated":219,"Significant":29,"Expected":13.23,"Rank in p.value_classic":341,"p.value_elim":0.03033,"p.value_classic":0.00006,"genes":"AURKB,BIRC5,BUB1B,CDC6,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,EML4,KIF11,KIF18B,KIF23,MAD2L1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PRC1,RMI2,SPC24,SPC25,TOP2A,UHRF1,ZWINT"} {"GO.ID":"GO:1902850","Term":"microtubule cytoskeleton organization involved in mitosis","Annotated":157,"Significant":19,"Expected":9.48,"Rank in p.value_classic":590,"p.value_elim":0.03051,"p.value_classic":0.00292,"genes":"AURKB,BIRC5,CDK1,CHMP4C,DYNLT1,KIF11,KIF23,MAD2L1,MYBL2,NDC80,NUF2,NUSAP1,PARP3,PRC1,SPC25,STMN1,TACC2,UHRF1,WDR62"} {"GO.ID":"GO:0002293","Term":"alpha-beta T cell differentiation involved in immune response","Annotated":69,"Significant":16,"Expected":4.17,"Rank in p.value_classic":252,"p.value_elim":0.03055,"p.value_classic":2.5e-06,"genes":"ASCL2,BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0002294","Term":"CD4-positive, alpha-beta T cell differentiation involved in immune response","Annotated":69,"Significant":16,"Expected":4.17,"Rank in p.value_classic":253,"p.value_elim":0.03055,"p.value_classic":2.5e-06,"genes":"ASCL2,BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0002287","Term":"alpha-beta T cell activation involved in immune response","Annotated":69,"Significant":16,"Expected":4.17,"Rank in p.value_classic":254,"p.value_elim":0.03055,"p.value_classic":2.5e-06,"genes":"ASCL2,BCL6,CD80,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0051781","Term":"positive regulation of cell division","Annotated":73,"Significant":9,"Expected":4.41,"Rank in p.value_classic":977,"p.value_elim":0.03063,"p.value_classic":0.03107,"genes":"AURKB,BIRC5,CDC6,GAREM1,KIF23,LBH,OSM,TAL1,VEGFC"} {"GO.ID":"GO:0006956","Term":"complement activation","Annotated":35,"Significant":13,"Expected":2.11,"Rank in p.value_classic":174,"p.value_elim":0.03094,"p.value_classic":5.5e-08,"genes":"C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CFB,CFH,CR1L,FCN1,SERPING1"} {"GO.ID":"GO:2000108","Term":"positive regulation of leukocyte apoptotic process","Annotated":24,"Significant":10,"Expected":1.45,"Rank in p.value_classic":214,"p.value_elim":0.03118,"p.value_classic":5.5e-07,"genes":"ADAM8,BCL2L11,CCL5,CD274,HCAR2,IDO1,LYN,P2RX7,PDCD1,RAPGEF2"} {"GO.ID":"GO:0000070","Term":"mitotic sister chromatid segregation","Annotated":181,"Significant":26,"Expected":10.93,"Rank in p.value_classic":326,"p.value_elim":0.03119,"p.value_classic":0.00003,"genes":"AURKB,BIRC5,BUB1B,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,EML4,KIF11,KIF18B,KIF23,MAD2L1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PRC1,SPC24,SPC25,UHRF1,ZWINT"} {"GO.ID":"GO:1902622","Term":"regulation of neutrophil migration","Annotated":40,"Significant":6,"Expected":2.42,"Rank in p.value_classic":978,"p.value_elim":0.03122,"p.value_classic":0.03155,"genes":"ADAM8,CD74,EDN1,NOD2,SLAMF8,TNFAIP6"} {"GO.ID":"GO:0032755","Term":"positive regulation of interleukin-6 production","Annotated":85,"Significant":10,"Expected":5.13,"Rank in p.value_classic":979,"p.value_elim":0.03126,"p.value_classic":0.03173,"genes":"CD74,IFIH1,LILRA2,LPL,NOD2,P2RX7,RIPK2,SCIMP,TLR7,TLR8"} {"GO.ID":"GO:0061982","Term":"meiosis I cell cycle process","Annotated":92,"Significant":14,"Expected":5.56,"Rank in p.value_classic":509,"p.value_elim":0.03157,"p.value_classic":0.00119,"genes":"BCL2L11,CCNE2,CDC25A,DMC1,EME1,HORMAD1,MEIKIN,NDC80,PKMYT1,RAD54B,RAD54L,TDRD9,TOP2A,ZWINT"} {"GO.ID":"GO:0071695","Term":"anatomical structure maturation","Annotated":186,"Significant":18,"Expected":11.23,"Rank in p.value_classic":1001,"p.value_elim":0.03169,"p.value_classic":0.03237,"genes":"C3,CDH5,CX3CR1,DAZL,DMC1,EDN1,EPAS1,GLDN,IL15,LRRK2,NRCAM,S1PR1,SCARF1,SNX10,SPTBN4,TAL1,TYMS,XYLT1"} {"GO.ID":"GO:0032692","Term":"negative regulation of interleukin-1 production","Annotated":29,"Significant":8,"Expected":1.75,"Rank in p.value_classic":400,"p.value_elim":0.03174,"p.value_classic":0.00024,"genes":"CARD16,CEACAM1,CX3CR1,GHRL,MEFV,NLRP12,PML,ZC3H12A"} {"GO.ID":"GO:0032091","Term":"negative regulation of protein binding","Annotated":62,"Significant":8,"Expected":3.74,"Rank in p.value_classic":1000,"p.value_elim":0.03178,"p.value_classic":0.03219,"genes":"AURKB,B2M,CARD16,DAB2,IFIT2,LRRK2,RALB,XIRP1"} {"GO.ID":"GO:0001956","Term":"positive regulation of neurotransmitter secretion","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":980,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"DTNBP1,STX1A,SYT1"} {"GO.ID":"GO:1903977","Term":"positive regulation of glial cell migration","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":981,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"CSF1,CX3CR1,P2RX4"} {"GO.ID":"GO:0070207","Term":"protein homotrimerization","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":982,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"ASIC1,HLA-G,STEAP4"} {"GO.ID":"GO:0048012","Term":"hepatocyte growth factor receptor signaling pathway","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":983,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"HGF,NRP1,STMN1"} {"GO.ID":"GO:0034144","Term":"negative regulation of toll-like receptor 4 signaling pathway","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":984,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"ACOD1,LILRA2,LYN"} {"GO.ID":"GO:0034135","Term":"regulation of toll-like receptor 2 signaling pathway","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":985,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"ACOD1,LYN,NOD2"} {"GO.ID":"GO:0010649","Term":"regulation of cell communication by electrical coupling","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":986,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0070672","Term":"response to interleukin-15","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":987,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"IL15,IL15RA,JAK3"} {"GO.ID":"GO:0045006","Term":"DNA deamination","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":988,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0051132","Term":"NK T cell activation","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":989,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"IL12A,IL15,JAK2"} {"GO.ID":"GO:2000846","Term":"regulation of corticosteroid hormone secretion","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":990,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"AGT,DAB2,GHRL"} {"GO.ID":"GO:0021535","Term":"cell migration in hindbrain","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":991,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"ATP1B2,DAB1,PLXNA2"} {"GO.ID":"GO:0009074","Term":"aromatic amino acid family catabolic process","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":992,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0098883","Term":"synapse pruning","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":993,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"C1QB,C3,CX3CR1"} {"GO.ID":"GO:0045779","Term":"negative regulation of bone resorption","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":994,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"CD38,P2RX7,TMEM119"} {"GO.ID":"GO:0002923","Term":"regulation of humoral immune response mediated by circulating immunoglobulin","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":995,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"CR1L,LTA,NOD2"} {"GO.ID":"GO:2001267","Term":"regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway","Annotated":12,"Significant":3,"Expected":0.72,"Rank in p.value_classic":996,"p.value_elim":0.03183,"p.value_classic":0.03204,"genes":"FAS,JAK2,MMP9"} {"GO.ID":"GO:0045429","Term":"positive regulation of nitric oxide biosynthetic process","Annotated":30,"Significant":5,"Expected":1.81,"Rank in p.value_classic":997,"p.value_elim":0.03185,"p.value_classic":0.03215,"genes":"EDN1,JAK2,KLF4,KLRK1,P2RX4"} {"GO.ID":"GO:0045577","Term":"regulation of B cell differentiation","Annotated":30,"Significant":5,"Expected":1.81,"Rank in p.value_classic":998,"p.value_elim":0.03185,"p.value_classic":0.03215,"genes":"BCL6,CYLD,IL4I1,IL7,SLAMF8"} {"GO.ID":"GO:0080164","Term":"regulation of nitric oxide metabolic process","Annotated":51,"Significant":7,"Expected":3.08,"Rank in p.value_classic":1003,"p.value_elim":0.03217,"p.value_classic":0.03255,"genes":"CX3CR1,EDN1,JAK2,KLF4,KLRK1,P2RX4,ZC3H12A"} {"GO.ID":"GO:0032757","Term":"positive regulation of interleukin-8 production","Annotated":51,"Significant":7,"Expected":3.08,"Rank in p.value_classic":1004,"p.value_elim":0.03217,"p.value_classic":0.03255,"genes":"CD74,FCN1,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"GO.ID":"GO:0002763","Term":"positive regulation of myeloid leukocyte differentiation","Annotated":51,"Significant":7,"Expected":3.08,"Rank in p.value_classic":1005,"p.value_elim":0.03217,"p.value_classic":0.03255,"genes":"CD101,CD74,CSF1,HLA-DRB1,KITLG,TESC,TNFRSF11A"} {"GO.ID":"GO:0052548","Term":"regulation of endopeptidase activity","Annotated":213,"Significant":20,"Expected":12.86,"Rank in p.value_classic":1006,"p.value_elim":0.03242,"p.value_classic":0.03316,"genes":"AIM2,ATP13A2,CARD16,FAS,GRAMD4,JAK2,KLF4,LAMP3,LYN,MEFV,MMP9,NLRP12,PMAIP1,PSMB8,PSMB9,PSME1,PSME2,RIPK2,SERPING1,TNFSF10"} {"GO.ID":"GO:0007292","Term":"female gamete generation","Annotated":110,"Significant":12,"Expected":6.64,"Rank in p.value_classic":1007,"p.value_elim":0.03286,"p.value_classic":0.03341,"genes":"DAZL,DMC1,EDN1,HORMAD1,MEIKIN,NCAPH,NDC80,NPM2,PAQR5,PAQR8,TNFAIP6,TOP2A"} {"GO.ID":"GO:0002831","Term":"regulation of response to biotic stimulus","Annotated":437,"Significant":76,"Expected":26.39,"Rank in p.value_classic":34,"p.value_elim":0.03297,"p.value_classic":2.4e-17,"genes":"ACOD1,ADAM8,AIM2,APOBEC3G,APPL2,AURKB,CARD16,CCL5,CD274,CD300LF,CEACAM1,CFH,CLEC6A,COLEC12,CTSS,CYLD,DDX60,DTX3L,FCN1,FGL2,GBP2,GBP5,GRAMD4,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL27,IL4I1,IRF1,IRF4,IRF7,KLRK1,LAG3,LILRA2,LYN,MEFV,NCF1,NLRC5,NMI,NOD2,OAS3,OPTN,PARP14,PARP9,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF6,SLAMF8,STAT1,STAT2,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0006641","Term":"triglyceride metabolic process","Annotated":74,"Significant":9,"Expected":4.47,"Rank in p.value_classic":1009,"p.value_elim":0.03309,"p.value_classic":0.03355,"genes":"ACSL1,C3,DGAT2,G6PC1,GK,LPL,PLAAT3,PLB1,PNPLA3"} {"GO.ID":"GO:0050871","Term":"positive regulation of B cell activation","Annotated":74,"Significant":9,"Expected":4.47,"Rank in p.value_classic":1010,"p.value_elim":0.03309,"p.value_classic":0.03355,"genes":"BCL6,CD28,CD38,CD74,GPR183,IL7,NOD2,TBX21,TNFSF13B"} {"GO.ID":"GO:0071241","Term":"cellular response to inorganic substance","Annotated":187,"Significant":18,"Expected":11.29,"Rank in p.value_classic":1011,"p.value_elim":0.03317,"p.value_classic":0.03389,"genes":"ATP13A2,B2M,CAMK2D,CCNA2,CRHBP,CYP1A1,EDN1,HESX1,KCNJ10,LRRK2,MMP9,MT2A,NCF1,P2RX4,SLC11A1,SLC12A3,SYT1,SYT6"} {"GO.ID":"GO:0034219","Term":"carbohydrate transmembrane transport","Annotated":98,"Significant":11,"Expected":5.92,"Rank in p.value_classic":1012,"p.value_elim":0.0334,"p.value_classic":0.03394,"genes":"APPL2,C3,CTNS,EDN1,NR4A3,PID1,SLC2A5,SLC2A6,SLC45A3,SLC45A4,TMEM144"} {"GO.ID":"GO:0031349","Term":"positive regulation of defense response","Annotated":414,"Significant":70,"Expected":25,"Rank in p.value_classic":49,"p.value_elim":0.0338,"p.value_classic":2.1e-15,"genes":"ACOD1,ADAM8,AGT,AIM2,APPL2,AURKB,C3,CASP4,CCL5,CD274,CD28,CD300LF,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,GSDMD,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL15,IRF1,IRF4,IRF7,KARS1,KLRK1,LAG3,LILRA2,LPL,LRRK2,LTA,LYN,MEFV,NLRC5,NLRP12,NMI,NOD2,OAS3,OPTN,OSM,PARP9,PLSCR1,PTGER4,PYHIN1,RIPK2,RSAD2,SCIMP,SLAMF6,STAP1,SUCNR1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF11A,TRIM31,TYRO3,ZBP1,ZNFX1"} {"GO.ID":"GO:0051098","Term":"regulation of binding","Annotated":214,"Significant":20,"Expected":12.92,"Rank in p.value_classic":1015,"p.value_elim":0.03383,"p.value_classic":0.0346,"genes":"AURKB,B2M,CARD16,CDT1,DAB2,DTX3L,E2F1,HJURP,IFIT2,JAK2,LRRK2,MMP9,NRP1,PARP9,PYHIN1,RALB,RAPGEF2,RIPK2,STMN1,XIRP1"} {"GO.ID":"GO:0045839","Term":"negative regulation of mitotic nuclear division","Annotated":53,"Significant":10,"Expected":3.2,"Rank in p.value_classic":498,"p.value_elim":0.03417,"p.value_classic":0.00111,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0009435","Term":"NAD biosynthetic process","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1016,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"IDO1,IDO2,PARP10,PARP9"} {"GO.ID":"GO:0010613","Term":"positive regulation of cardiac muscle hypertrophy","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1017,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"AGT,CAMK2D,EDN1,NR4A3"} {"GO.ID":"GO:0032197","Term":"retrotransposition","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1018,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"APOBEC3A,APOBEC3G,PIWIL4,TDRD9"} {"GO.ID":"GO:0014742","Term":"positive regulation of muscle hypertrophy","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1019,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"AGT,CAMK2D,EDN1,NR4A3"} {"GO.ID":"GO:0051383","Term":"kinetochore organization","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1020,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"CENPF,CENPK,NDC80,NUF2"} {"GO.ID":"GO:0055075","Term":"potassium ion homeostasis","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1021,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"ATP1B2,KCNJ10,KCNJ2,SLC12A3"} {"GO.ID":"GO:0046337","Term":"phosphatidylethanolamine metabolic process","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1022,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"NAAA,PLAAT3,PLAAT4,PLB1"} {"GO.ID":"GO:0046426","Term":"negative regulation of receptor signaling pathway via JAK-STAT","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1023,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"DAB1,GBP7,PARP14,SOCS1"} {"GO.ID":"GO:0009072","Term":"aromatic amino acid metabolic process","Annotated":21,"Significant":4,"Expected":1.27,"Rank in p.value_classic":1024,"p.value_elim":0.03444,"p.value_classic":0.03472,"genes":"IDO1,IDO2,IL4I1,OCA2"} {"GO.ID":"GO:0042116","Term":"macrophage activation","Annotated":92,"Significant":15,"Expected":5.56,"Rank in p.value_classic":430,"p.value_elim":0.03446,"p.value_classic":0.00038,"genes":"CD74,CD93,CX3CR1,DYSF,IFI35,IL31RA,JAK2,KARS1,LRRK2,NMI,SBNO2,SLC11A1,STAP1,SUCNR1,ZC3H12A"} {"GO.ID":"GO:0022600","Term":"digestive system process","Annotated":63,"Significant":8,"Expected":3.8,"Rank in p.value_classic":1025,"p.value_elim":0.03455,"p.value_classic":0.035,"genes":"GCNT3,GHRL,HRH2,NOD2,SLC2A5,SNX10,TIFAB,TYMP"} {"GO.ID":"GO:0045132","Term":"meiotic chromosome segregation","Annotated":63,"Significant":8,"Expected":3.8,"Rank in p.value_classic":1026,"p.value_elim":0.03455,"p.value_classic":0.035,"genes":"CCNE2,DMC1,HORMAD1,MEIKIN,NCAPH,NDC80,NUF2,ZWINT"} {"GO.ID":"GO:0006809","Term":"nitric oxide biosynthetic process","Annotated":63,"Significant":8,"Expected":3.8,"Rank in p.value_classic":1027,"p.value_elim":0.03455,"p.value_classic":0.035,"genes":"CX3CR1,EDN1,GCH1,JAK2,KLF4,KLRK1,P2RX4,ZC3H12A"} {"GO.ID":"GO:0032480","Term":"negative regulation of type I interferon production","Annotated":41,"Significant":6,"Expected":2.48,"Rank in p.value_classic":1028,"p.value_elim":0.03477,"p.value_classic":0.03514,"genes":"ACOD1,CYLD,GBP7,NMI,RELB,XAF1"} {"GO.ID":"GO:0032715","Term":"negative regulation of interleukin-6 production","Annotated":41,"Significant":6,"Expected":2.48,"Rank in p.value_classic":1029,"p.value_elim":0.03477,"p.value_classic":0.03514,"genes":"BANK1,GHRL,HGF,NLRP12,SLAMF1,ZC3H12A"} {"GO.ID":"GO:0031347","Term":"regulation of defense response","Annotated":655,"Significant":102,"Expected":39.56,"Rank in p.value_classic":23,"p.value_elim":0.03487,"p.value_classic":2.1e-19,"genes":"ACOD1,ADAM8,AGT,AIM2,APOBEC3G,APPL2,AURKB,BCL6,C3,CARD16,CASP4,CCL5,CD274,CD28,CD300LF,CDH5,CEACAM1,CFH,CLEC6A,COLEC12,CTSS,CYLD,DDX60,DTX3L,FCN1,FGL2,GBP2,GBP5,GHRL,GPR31,GRAMD4,GSDMD,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL22RA2,IL27,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,KLRK1,LAG3,LILRA2,LPL,LRRK2,LTA,LYN,MEFV,MMP9,NCF1,NLRC5,NLRP12,NMI,NOD2,OAS3,OPTN,OSM,PARP14,PARP9,PLSCR1,PTGER4,PYHIN1,RIPK2,RSAD2,SBNO2,SCIMP,SERPING1,SLAMF6,SLAMF8,STAP1,STAT1,STAT2,SUCNR1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0050000","Term":"chromosome localization","Annotated":111,"Significant":12,"Expected":6.7,"Rank in p.value_classic":1031,"p.value_elim":0.03491,"p.value_classic":0.03549,"genes":"AURKB,BIRC5,CDCA5,CDT1,CENPF,CHMP4C,EML4,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0043491","Term":"phosphatidylinositol 3-kinase/protein kinase B signal transduction","Annotated":242,"Significant":22,"Expected":14.62,"Rank in p.value_classic":1034,"p.value_elim":0.0353,"p.value_classic":0.03615,"genes":"ADAM8,AGT,AIM2,BANK1,BTN2A2,CCL5,CD28,CD40,CEACAM1,CX3CR1,EDN1,HBEGF,HGF,HLA-G,JAK2,MERTK,NCF1,NYAP2,OSM,P2RX4,SESN3,TYRO3"} {"GO.ID":"GO:0048144","Term":"fibroblast proliferation","Annotated":99,"Significant":11,"Expected":5.98,"Rank in p.value_classic":1035,"p.value_elim":0.03562,"p.value_classic":0.03618,"genes":"AGT,CCNA2,CD74,CDC6,CDK1,E2F1,E2F8,GNG2,LTA,PARP10,PML"} {"GO.ID":"GO:0050433","Term":"regulation of catecholamine secretion","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1036,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"ADORA3,DTNBP1,STX1A,SYT1,SYT6"} {"GO.ID":"GO:0030224","Term":"monocyte differentiation","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1037,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"CD74,CSF1,HLA-DRB1,IL31RA,IRF7"} {"GO.ID":"GO:0002431","Term":"Fc receptor mediated stimulatory signaling pathway","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1038,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"APPL2,LYN,NR4A3,PLPP4,PLSCR1"} {"GO.ID":"GO:2000406","Term":"positive regulation of T cell migration","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1039,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"ADAM8,ASCL2,CCL5,CXCL10,TNFRSF14"} {"GO.ID":"GO:1904407","Term":"positive regulation of nitric oxide metabolic process","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1040,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"EDN1,JAK2,KLF4,KLRK1,P2RX4"} {"GO.ID":"GO:0007431","Term":"salivary gland development","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1041,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"EDA,HGF,NRP1,POLB,TGM2"} {"GO.ID":"GO:0071276","Term":"cellular response to cadmium ion","Annotated":31,"Significant":5,"Expected":1.87,"Rank in p.value_classic":1042,"p.value_elim":0.03615,"p.value_classic":0.03649,"genes":"HESX1,MMP9,MT2A,NCF1,SLC11A1"} {"GO.ID":"GO:0009968","Term":"negative regulation of signal transduction","Annotated":1102,"Significant":90,"Expected":66.56,"Rank in p.value_classic":540,"p.value_elim":0.03622,"p.value_classic":0.00176,"genes":"ACOD1,AGT,AIM2,AMER1,ATF3,AURKB,BANK1,BCL6,BRCA1,BTN2A2,CARD16,CASTOR1,CCL5,CD300LF,CD74,CEACAM1,CHAC1,CHRD,CISH,CRHBP,CX3CR1,CYLD,DAB1,DAB2,DEPTOR,DHRS3,DKK2,DLL1,FSTL4,GBP1,GBP7,GRAMD4,HELLS,HGF,HLA-G,HTRA1,ICAM1,IFI35,IFT122,IL12A,IL1RN,IL7,IRF4,KIF26A,KREMEN1,LBH,LILRA2,LITAF,LRRK2,LYN,MEFV,MIR503,MMP9,MUC1,MVP,MYOZ2,NECAB2,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,ONECUT2,OPTN,P2RX7,PADI2,PARP14,PDE3B,PDE4B,PID1,PLEK,PTPRU,RGS18,RNF213,SESN3,SLAMF1,SOCS1,SOX17,STAP1,STAT1,STAT2,STMN1,TANK,TNFAIP6,TRABD2A,TRIM31,TSPAN15,TYRO3,ZC3H12A"} {"GO.ID":"GO:0009991","Term":"response to extracellular stimulus","Annotated":410,"Significant":34,"Expected":24.76,"Rank in p.value_classic":1044,"p.value_elim":0.03624,"p.value_classic":0.03736,"genes":"ACSL1,APPL2,ATF3,C2,CASTOR1,CD40,CXCL10,CYP1A1,FAM107A,FAS,GHRL,GLUL,GSDMD,IL15RA,KIF26A,LPL,LRRK2,LTA,LYN,MAP1LC3C,NOD2,P2RX7,PDK4,PIM1,PMAIP1,RALB,SESN3,SLC12A3,SSTR2,STAT1,TNFRSF11A,TYMS,VCAM1,ZC3H12A"} {"GO.ID":"GO:2001236","Term":"regulation of extrinsic apoptotic signaling pathway","Annotated":137,"Significant":14,"Expected":8.27,"Rank in p.value_classic":1043,"p.value_elim":0.03651,"p.value_classic":0.03718,"genes":"AGT,ATF3,BCL2L14,BRCA1,CYLD,DEPTOR,G0S2,HGF,ICAM1,IL7,NRP1,PMAIP1,PML,TNFSF10"} {"GO.ID":"GO:0051302","Term":"regulation of cell division","Annotated":150,"Significant":15,"Expected":9.06,"Rank in p.value_classic":1045,"p.value_elim":0.03679,"p.value_classic":0.03749,"genes":"AURKB,BIRC5,CDC6,CHMP4C,DLL1,E2F8,GAREM1,KIF18B,KIF23,LBH,OSM,PRC1,SOX17,TAL1,VEGFC"} {"GO.ID":"GO:0071248","Term":"cellular response to metal ion","Annotated":163,"Significant":16,"Expected":9.84,"Rank in p.value_classic":1046,"p.value_elim":0.03682,"p.value_classic":0.03754,"genes":"ATP13A2,B2M,CAMK2D,CRHBP,CYP1A1,EDN1,HESX1,KCNJ10,LRRK2,MMP9,MT2A,NCF1,P2RX4,SLC11A1,SYT1,SYT6"} {"GO.ID":"GO:0051304","Term":"chromosome separation","Annotated":77,"Significant":14,"Expected":4.65,"Rank in p.value_classic":386,"p.value_elim":0.03739,"p.value_classic":0.00018,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,PLSCR1,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:2000177","Term":"regulation of neural precursor cell proliferation","Annotated":76,"Significant":9,"Expected":4.59,"Rank in p.value_classic":1047,"p.value_elim":0.0384,"p.value_classic":0.03893,"genes":"APPL2,CX3CR1,HAPLN3,LRRK2,LYN,SHCBP1,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0051445","Term":"regulation of meiotic cell cycle","Annotated":53,"Significant":7,"Expected":3.2,"Rank in p.value_classic":1049,"p.value_elim":0.03866,"p.value_classic":0.03911,"genes":"CDC25A,DAZL,HORMAD1,NPM2,OVOL1,PKMYT1,ZWINT"} {"GO.ID":"GO:0050918","Term":"positive chemotaxis","Annotated":53,"Significant":7,"Expected":3.2,"Rank in p.value_classic":1050,"p.value_elim":0.03866,"p.value_classic":0.03911,"genes":"CCL15,CCL5,CXCL10,HGF,NRP1,S1PR1,VEGFC"} {"GO.ID":"GO:0098813","Term":"nuclear chromosome segregation","Annotated":278,"Significant":33,"Expected":16.79,"Rank in p.value_classic":377,"p.value_elim":0.03889,"p.value_classic":0.00015,"genes":"AURKB,BIRC5,BUB1B,CCNE2,CDC6,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,DMC1,EML4,HORMAD1,KIF11,KIF18B,KIF23,MAD2L1,MEIKIN,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,PRC1,RMI2,SPC24,SPC25,TOP2A,UHRF1,ZWINT"} {"GO.ID":"GO:1905155","Term":"positive regulation of membrane invagination","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1052,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"APPL2,C3,STAP1"} {"GO.ID":"GO:1900044","Term":"regulation of protein K63-linked ubiquitination","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1053,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"NOD2,PARP10,RIPK2"} {"GO.ID":"GO:0070493","Term":"thrombin-activated receptor signaling pathway","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1054,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"F2RL3,PLEK,STMN1"} {"GO.ID":"GO:0060100","Term":"positive regulation of phagocytosis, engulfment","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1055,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"APPL2,C3,STAP1"} {"GO.ID":"GO:0044320","Term":"cellular response to leptin stimulus","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1056,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"CCNA2,NR4A3,PID1"} {"GO.ID":"GO:0043374","Term":"CD8-positive, alpha-beta T cell differentiation","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1057,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"IRF1,SOCS1,TNFSF8"} {"GO.ID":"GO:1900120","Term":"regulation of receptor binding","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1058,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"B2M,MMP9,NRP1"} {"GO.ID":"GO:0061000","Term":"negative regulation of dendritic spine development","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1059,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"DTNBP1,FSTL4,GRIN3A"} {"GO.ID":"GO:1904177","Term":"regulation of adipose tissue development","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1060,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"GHRL,LPL,PLAAT3"} {"GO.ID":"GO:0051177","Term":"meiotic sister chromatid cohesion","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1061,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"BUB1B,HORMAD1,MEIKIN"} {"GO.ID":"GO:0016446","Term":"somatic hypermutation of immunoglobulin genes","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1062,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"EXO1,POLB,UNG"} {"GO.ID":"GO:0002829","Term":"negative regulation of type 2 immune response","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1063,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"ASCL2,BCL6,TBX21"} {"GO.ID":"GO:0002517","Term":"T cell tolerance induction","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1064,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"HLA-B,HLA-G,IDO1"} {"GO.ID":"GO:0071639","Term":"positive regulation of monocyte chemotactic protein-1 production","Annotated":13,"Significant":3,"Expected":0.79,"Rank in p.value_classic":1065,"p.value_elim":0.03957,"p.value_classic":0.03983,"genes":"MCOLN2,NOD2,OAS3"} {"GO.ID":"GO:1903707","Term":"negative regulation of hemopoiesis","Annotated":93,"Significant":18,"Expected":5.62,"Rank in p.value_classic":282,"p.value_elim":0.04013,"p.value_classic":9.4e-06,"genes":"ASCL2,BCL6,CD74,CEACAM1,CTLA4,FGL2,HLA-G,IRF1,JAK3,LAG3,LILRB3,LYN,SOCS1,TBX21,TMEM176A,TMEM176B,TNFAIP6,ZC3H12A"} {"GO.ID":"GO:0072593","Term":"reactive oxygen species metabolic process","Annotated":178,"Significant":17,"Expected":10.75,"Rank in p.value_classic":1068,"p.value_elim":0.04014,"p.value_classic":0.04095,"genes":"ACOD1,AGT,BRCA1,CTNS,CYP1A1,DHFR,EDN1,GCH1,LRRK2,NCF1,NCF1C,P2RX7,PDK4,PID1,PMAIP1,SH3PXD2A,ZC3H12A"} {"GO.ID":"GO:0019731","Term":"antibacterial humoral response","Annotated":22,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1066,"p.value_elim":0.04015,"p.value_classic":0.04047,"genes":"H2BC21,HLA-A,HLA-E,NOD2"} {"GO.ID":"GO:0060252","Term":"positive regulation of glial cell proliferation","Annotated":22,"Significant":4,"Expected":1.33,"Rank in p.value_classic":1067,"p.value_elim":0.04015,"p.value_classic":0.04047,"genes":"CYSLTR1,LTA,LYN,VEGFC"} {"GO.ID":"GO:0051899","Term":"membrane depolarization","Annotated":65,"Significant":8,"Expected":3.93,"Rank in p.value_classic":1070,"p.value_elim":0.0406,"p.value_classic":0.04111,"genes":"ANK2,CAMK2D,EDN1,KCNJ2,LRRK2,P2RX4,P2RX7,SCN4B"} {"GO.ID":"GO:0042572","Term":"retinol metabolic process","Annotated":32,"Significant":5,"Expected":1.93,"Rank in p.value_classic":1071,"p.value_elim":0.0408,"p.value_classic":0.04118,"genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"GO.ID":"GO:0002252","Term":"immune effector process","Annotated":488,"Significant":90,"Expected":29.47,"Rank in p.value_classic":18,"p.value_elim":0.04122,"p.value_classic":3.3e-22,"genes":"APPL2,ASCL2,B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD28,CD40,CD74,CD80,CEACAM1,CFB,CFH,CR1L,CSF2RB,CX3CR1,DDX60,DLL1,DYSF,EXO1,FCN1,FGL2,GPR183,HLA-A,HLA-B,HLA-C,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IFI35,IL12A,IL12RB1,IL27,IL4I1,IRF4,IRF7,JAK3,KARS1,KLRK1,LAG3,LILRA2,LITAF,LTA,LYN,NCF1,NMI,NOD2,NR4A3,P2RX7,PARP3,PLPP4,PTGER4,RELB,RIPK2,RNF19B,RSAD2,S100A13,SBNO2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,SUCNR1,TAP2,TBX21,TICAM2,TLR7,TLR8,TNFRSF14,TNFSF18,UNG,ZC3H12A"} {"GO.ID":"GO:0002526","Term":"acute inflammatory response","Annotated":77,"Significant":9,"Expected":4.65,"Rank in p.value_classic":1072,"p.value_elim":0.04126,"p.value_classic":0.04182,"genes":"ADAM8,APOL2,C3,CD163,HLA-E,IL31RA,OSM,PLSCR1,TNFRSF11A"} {"GO.ID":"GO:0010972","Term":"negative regulation of G2/M transition of mitotic cell cycle","Annotated":64,"Significant":11,"Expected":3.87,"Rank in p.value_classic":520,"p.value_elim":0.04138,"p.value_classic":0.00143,"genes":"AURKB,BRCA1,CDC6,CDK1,CHMP4C,CLSPN,DTL,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0007062","Term":"sister chromatid cohesion","Annotated":54,"Significant":7,"Expected":3.26,"Rank in p.value_classic":1074,"p.value_elim":0.04221,"p.value_classic":0.04269,"genes":"BUB1B,CDCA5,DSCC1,ESCO2,FEN1,HORMAD1,MEIKIN"} {"GO.ID":"GO:0015844","Term":"monoamine transport","Annotated":54,"Significant":7,"Expected":3.26,"Rank in p.value_classic":1075,"p.value_elim":0.04221,"p.value_classic":0.04269,"genes":"ADORA3,DTNBP1,SLC18A1,STX1A,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0010648","Term":"negative regulation of cell communication","Annotated":1172,"Significant":94,"Expected":70.78,"Rank in p.value_classic":561,"p.value_elim":0.04223,"p.value_classic":0.00242,"genes":"ACOD1,AGT,AIM2,AMER1,ATF3,AURKB,BANK1,BCL6,BRCA1,BTN2A2,CARD16,CASTOR1,CCL5,CD300LF,CD38,CD74,CEACAM1,CHAC1,CHRD,CISH,CRHBP,CX3CR1,CYLD,DAB1,DAB2,DEPTOR,DHRS3,DKK2,DLL1,EDN1,FSTL4,GBP1,GBP7,GHRL,GRAMD4,HELLS,HGF,HLA-G,HTRA1,ICAM1,IFI35,IFT122,IL12A,IL1RN,IL7,IRF4,KIF26A,KREMEN1,LBH,LILRA2,LITAF,LRRK2,LYN,MEFV,MIR503,MMP9,MUC1,MVP,MYOZ2,NECAB2,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX7,PADI2,PARP14,PDE3B,PDE4B,PID1,PLEK,PTPRU,RGS18,RNF213,SESN3,SLAMF1,SOCS1,SOX17,STAP1,STAT1,STAT2,STMN1,TANK,TNFAIP6,TRABD2A,TRIM31,TSPAN15,TYRO3,ZC3H12A"} {"GO.ID":"GO:2001235","Term":"positive regulation of apoptotic signaling pathway","Annotated":127,"Significant":13,"Expected":7.67,"Rank in p.value_classic":1076,"p.value_elim":0.04233,"p.value_classic":0.04305,"genes":"AGT,ATF3,BCL2L11,CTSL,CTSS,CYLD,FAS,G0S2,JAK2,PMAIP1,PML,SEPTIN4,TNFSF10"} {"GO.ID":"GO:0046651","Term":"lymphocyte proliferation","Annotated":243,"Significant":44,"Expected":14.68,"Rank in p.value_classic":100,"p.value_elim":0.04291,"p.value_classic":4.1e-11,"genes":"BCL6,BTN2A2,BTN3A1,CCL5,CD274,CD28,CD38,CD40,CD74,CD80,CTLA4,GPR183,HELLS,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,P2RX7,PDCD1LG2,PSMB10,RIPK2,SLAMF1,SLC11A1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0051336","Term":"regulation of hydrolase activity","Annotated":605,"Significant":47,"Expected":36.54,"Rank in p.value_classic":1079,"p.value_elim":0.04304,"p.value_classic":0.04461,"genes":"AIM2,ATP13A2,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CTSL,CTSS,EPHB3,FAS,FGD5,GRAMD4,ITK,JAK2,KLF4,KLRK1,LAMP3,LRRK2,LYN,MEFV,MMP9,NLRP12,OAS2,OAS3,PLEK,PLXNA2,PMAIP1,PSMB8,PSMB9,PSME1,PSME2,RAPGEF2,RASGEF1C,RASGRF1,RIPK2,RSU1,S100A10,SERPING1,STMN1,TANK,TGM2,TNFSF10,USP6NL"} {"GO.ID":"GO:0023057","Term":"negative regulation of signaling","Annotated":1174,"Significant":94,"Expected":70.9,"Rank in p.value_classic":571,"p.value_elim":0.04373,"p.value_classic":0.00254,"genes":"ACOD1,AGT,AIM2,AMER1,ATF3,AURKB,BANK1,BCL6,BRCA1,BTN2A2,CARD16,CASTOR1,CCL5,CD300LF,CD38,CD74,CEACAM1,CHAC1,CHRD,CISH,CRHBP,CX3CR1,CYLD,DAB1,DAB2,DEPTOR,DHRS3,DKK2,DLL1,EDN1,FSTL4,GBP1,GBP7,GHRL,GRAMD4,HELLS,HGF,HLA-G,HTRA1,ICAM1,IFI35,IFT122,IL12A,IL1RN,IL7,IRF4,KIF26A,KREMEN1,LBH,LILRA2,LITAF,LRRK2,LYN,MEFV,MIR503,MMP9,MUC1,MVP,MYOZ2,NECAB2,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX7,PADI2,PARP14,PDE3B,PDE4B,PID1,PLEK,PTPRU,RGS18,RNF213,SESN3,SLAMF1,SOCS1,SOX17,STAP1,STAT1,STAT2,STMN1,TANK,TNFAIP6,TRABD2A,TRIM31,TSPAN15,TYRO3,ZC3H12A"} {"GO.ID":"GO:0001525","Term":"angiogenesis","Annotated":460,"Significant":43,"Expected":27.78,"Rank in p.value_classic":588,"p.value_elim":0.04375,"p.value_classic":0.00284,"genes":"ADAM8,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,EPAS1,EPHB3,GHRL,GLUL,HLA-G,IL12A,KLF4,MIR503,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PML,PRKX,PROK2,RNF213,S1PR1,SAT1,SOX17,STAT1,TAL1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0097530","Term":"granulocyte migration","Annotated":121,"Significant":23,"Expected":7.31,"Rank in p.value_classic":223,"p.value_elim":0.04401,"p.value_classic":7.8e-07,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CSF1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,MCOLN2,NOD2,PDE4B,PTGER4,SLAMF1,SLAMF8,TNFAIP6"} {"GO.ID":"GO:0035710","Term":"CD4-positive, alpha-beta T cell activation","Annotated":104,"Significant":22,"Expected":6.28,"Rank in p.value_classic":195,"p.value_elim":0.04402,"p.value_classic":1.9e-07,"genes":"ASCL2,BCL6,CD274,CD28,CD80,CD83,CTSL,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:0002832","Term":"negative regulation of response to biotic stimulus","Annotated":98,"Significant":21,"Expected":5.92,"Rank in p.value_classic":204,"p.value_elim":0.04412,"p.value_classic":2.9e-07,"genes":"ACOD1,AURKB,CARD16,CEACAM1,FGL2,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,LILRA2,NLRC5,NMI,OAS3,PARP14,SERPING1,SLAMF8,STAT2,TRAFD1,TYRO3"} {"GO.ID":"GO:0002262","Term":"myeloid cell homeostasis","Annotated":154,"Significant":15,"Expected":9.3,"Rank in p.value_classic":1081,"p.value_elim":0.04475,"p.value_classic":0.04557,"genes":"ALAS1,B2M,BCL2L11,BCL6,CSF1,EPAS1,HCAR2,JAK2,KITLG,LYN,MERTK,NCAPG2,PDE4B,STAT1,TAL1"} {"GO.ID":"GO:0002819","Term":"regulation of adaptive immune response","Annotated":182,"Significant":41,"Expected":10.99,"Rank in p.value_classic":67,"p.value_elim":0.04477,"p.value_classic":1.2e-13,"genes":"ASCL2,B2M,BCL6,C3,CD1A,CD1C,CD274,CD28,CD80,CEACAM1,CLEC6A,CR1L,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,IL27,IL4I1,IRF1,IRF7,JAK2,JAK3,LTA,NOD2,P2RX7,PARP3,RIPK2,RSAD2,SLAMF1,SLC11A1,TAP2,TBX21,TNFRSF14,TNFSF13B,ZC3H12A"} {"GO.ID":"GO:0002708","Term":"positive regulation of lymphocyte mediated immunity","Annotated":102,"Significant":25,"Expected":6.16,"Rank in p.value_classic":127,"p.value_elim":0.04573,"p.value_classic":1.2e-09,"genes":"B2M,C3,CD1A,CD1C,CD28,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,KLRK1,LAG3,LTA,NOD2,P2RX7,RSAD2,SLAMF1,SLAMF6,TAP2,TBX21"} {"GO.ID":"GO:1900047","Term":"negative regulation of hemostasis","Annotated":33,"Significant":5,"Expected":1.99,"Rank in p.value_classic":1083,"p.value_elim":0.0458,"p.value_classic":0.04622,"genes":"CEACAM1,COMP,EDN1,SERPING1,THBD"} {"GO.ID":"GO:1903115","Term":"regulation of actin filament-based movement","Annotated":33,"Significant":5,"Expected":1.99,"Rank in p.value_classic":1084,"p.value_elim":0.0458,"p.value_classic":0.04622,"genes":"ANK2,CAMK2D,KCNJ2,PDE4B,SRI"} {"GO.ID":"GO:0070373","Term":"negative regulation of ERK1 and ERK2 cascade","Annotated":55,"Significant":7,"Expected":3.32,"Rank in p.value_classic":1086,"p.value_elim":0.04596,"p.value_classic":0.04648,"genes":"ATF3,BTN2A2,DAB2,GBP1,LYN,MIR503,NLRP12"} {"GO.ID":"GO:0055117","Term":"regulation of cardiac muscle contraction","Annotated":55,"Significant":7,"Expected":3.32,"Rank in p.value_classic":1087,"p.value_elim":0.04596,"p.value_classic":0.04648,"genes":"ANK2,CAMK2D,KCNJ2,P2RX4,PDE4B,SRI,ZC3H12A"} {"GO.ID":"GO:0090200","Term":"positive regulation of release of cytochrome c from mitochondria","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1088,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"BCL2L11,MMP9,PMAIP1,TNFSF10"} {"GO.ID":"GO:0032196","Term":"transposition","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1089,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"APOBEC3A,APOBEC3G,PIWIL4,TDRD9"} {"GO.ID":"GO:0071359","Term":"cellular response to dsRNA","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1090,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"COLEC12,IFIH1,P2RX7,RALB"} {"GO.ID":"GO:0032703","Term":"negative regulation of interleukin-2 production","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1091,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"GBP1,LAG3,NOD2,TBX21"} {"GO.ID":"GO:0034656","Term":"nucleobase-containing small molecule catabolic process","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1092,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4"} {"GO.ID":"GO:1901381","Term":"positive regulation of potassium ion transmembrane transport","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1093,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"ANK2,ATP1B2,KCNE5,KCNJ2"} {"GO.ID":"GO:1904893","Term":"negative regulation of receptor signaling pathway via STAT","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1094,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"DAB1,GBP7,PARP14,SOCS1"} {"GO.ID":"GO:0021602","Term":"cranial nerve morphogenesis","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1095,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"ATP8B1,EGR2,NRP1,TIFAB"} {"GO.ID":"GO:0006760","Term":"folic acid-containing compound metabolic process","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1096,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"DHFR,GCH1,MTHFD2,TYMS"} {"GO.ID":"GO:0019363","Term":"pyridine nucleotide biosynthetic process","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1097,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"IDO1,IDO2,PARP10,PARP9"} {"GO.ID":"GO:0019359","Term":"nicotinamide nucleotide biosynthetic process","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1098,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"IDO1,IDO2,PARP10,PARP9"} {"GO.ID":"GO:0007628","Term":"adult walking behavior","Annotated":23,"Significant":4,"Expected":1.39,"Rank in p.value_classic":1099,"p.value_elim":0.04637,"p.value_classic":0.04673,"genes":"CTNS,DAB1,KCNJ10,SPTBN4"} {"GO.ID":"GO:0045088","Term":"regulation of innate immune response","Annotated":369,"Significant":62,"Expected":22.29,"Rank in p.value_classic":68,"p.value_elim":0.0464,"p.value_classic":1.3e-13,"genes":"ACOD1,ADAM8,AIM2,APPL2,AURKB,CCL5,CD274,CD300LF,CEACAM1,CFH,CLEC6A,COLEC12,CTSS,CYLD,DDX60,FCN1,GBP2,GBP5,GRAMD4,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IFI35,IFIH1,IL12A,IRF1,IRF4,IRF7,KLRK1,LAG3,LILRA2,LYN,MEFV,NCF1,NLRC5,NMI,NOD2,OAS3,PARP14,PARP9,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF6,SLAMF8,STAT2,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TRAFD1,TRIM31,TYRO3,ZBP1,ZNFX1"} {"GO.ID":"GO:0007260","Term":"tyrosine phosphorylation of STAT protein","Annotated":57,"Significant":14,"Expected":3.44,"Rank in p.value_classic":270,"p.value_elim":0.04689,"p.value_classic":5.2e-06,"genes":"CCL5,CD40,IL12A,IL15,IL22RA2,IL31RA,JAK2,JAK3,LYN,OSM,PARP14,PARP9,SOCS1,TNFSF18"} {"GO.ID":"GO:0140374","Term":"antiviral innate immune response","Annotated":44,"Significant":6,"Expected":2.66,"Rank in p.value_classic":1100,"p.value_elim":0.04697,"p.value_classic":0.04745,"genes":"CXCL10,IFIH1,IFIT2,IFIT3,TRIM31,ZBP1"} {"GO.ID":"GO:0140894","Term":"endolysosomal toll-like receptor signaling pathway","Annotated":44,"Significant":6,"Expected":2.66,"Rank in p.value_classic":1101,"p.value_elim":0.04697,"p.value_classic":0.04745,"genes":"COLEC12,GRAMD4,RSAD2,SCIMP,TLR7,TLR8"} {"GO.ID":"GO:0031638","Term":"zymogen activation","Annotated":44,"Significant":6,"Expected":2.66,"Rank in p.value_classic":1102,"p.value_elim":0.04697,"p.value_classic":0.04745,"genes":"C1R,C1RL,CTSL,RIPK2,S100A10,THBD"} {"GO.ID":"GO:0006826","Term":"iron ion transport","Annotated":44,"Significant":6,"Expected":2.66,"Rank in p.value_classic":1103,"p.value_elim":0.04697,"p.value_classic":0.04745,"genes":"B2M,FLVCR2,LMTK2,SLC11A1,SLC25A28,STEAP4"} {"GO.ID":"GO:0071466","Term":"cellular response to xenobiotic stimulus","Annotated":129,"Significant":13,"Expected":7.79,"Rank in p.value_classic":1104,"p.value_elim":0.04703,"p.value_classic":0.04782,"genes":"ABCB1,ACSL1,AIM2,CBR3,CD69,CRHBP,CYP1A1,E2F1,EDN1,EPHX1,MCM7,PDE4B,PPM1E"} {"GO.ID":"GO:2000573","Term":"positive regulation of DNA biosynthetic process","Annotated":67,"Significant":8,"Expected":4.05,"Rank in p.value_classic":1105,"p.value_elim":0.0473,"p.value_classic":0.04789,"genes":"AURKB,CCNA2,CHTF18,DSCC1,GCH1,HGF,KLF4,PKIB"} {"GO.ID":"GO:0046640","Term":"regulation of alpha-beta T cell proliferation","Annotated":35,"Significant":8,"Expected":2.11,"Rank in p.value_classic":487,"p.value_elim":0.0476,"p.value_classic":0.00093,"genes":"CD274,CD28,HLA-A,HLA-E,IRF1,JAK2,RIPK2,TNFRSF14"} {"GO.ID":"GO:0009263","Term":"deoxyribonucleotide biosynthetic process","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1107,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"CMPK2,RRM2,TYMS"} {"GO.ID":"GO:0009265","Term":"2'-deoxyribonucleotide biosynthetic process","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1108,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"CMPK2,RRM2,TYMS"} {"GO.ID":"GO:0010759","Term":"positive regulation of macrophage chemotaxis","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1109,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"CCL5,CSF1,SLAMF1"} {"GO.ID":"GO:0046385","Term":"deoxyribose phosphate biosynthetic process","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1110,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"CMPK2,RRM2,TYMS"} {"GO.ID":"GO:0035435","Term":"phosphate ion transmembrane transport","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1111,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"ANKH,SLC20A1,SLC37A1"} {"GO.ID":"GO:0002566","Term":"somatic diversification of immune receptors via somatic mutation","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1112,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"EXO1,POLB,UNG"} {"GO.ID":"GO:0051782","Term":"negative regulation of cell division","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1113,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"AURKB,CHMP4C,E2F8"} {"GO.ID":"GO:2000696","Term":"regulation of epithelial cell differentiation involved in kidney development","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1114,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"MMP9,PRKX,STAT1"} {"GO.ID":"GO:0046851","Term":"negative regulation of bone remodeling","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1115,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"CD38,P2RX7,TMEM119"} {"GO.ID":"GO:0035729","Term":"cellular response to hepatocyte growth factor stimulus","Annotated":14,"Significant":3,"Expected":0.85,"Rank in p.value_classic":1116,"p.value_elim":0.04817,"p.value_classic":0.04848,"genes":"APPL2,HGF,NRP1"} {"GO.ID":"GO:0008643","Term":"carbohydrate transport","Annotated":117,"Significant":12,"Expected":7.07,"Rank in p.value_classic":1117,"p.value_elim":0.04915,"p.value_classic":0.04994,"genes":"APPL2,C3,CTNS,EDN1,NR4A3,PID1,SLC2A5,SLC2A6,SLC37A1,SLC45A3,SLC45A4,TMEM144"} {"GO.ID":"GO:0010959","Term":"regulation of metal ion transport","Annotated":279,"Significant":24,"Expected":16.85,"Rank in p.value_classic":1120,"p.value_elim":0.04982,"p.value_classic":0.05102,"genes":"ANK2,ATP1B2,B2M,CAMK2D,CCL5,CXCL10,CXCL11,CXCL9,F2RL3,KCNE5,KCNJ2,LILRA2,LYN,P2RX4,P2RX7,PDE4B,PLPP4,PML,SCN4B,SLC31A2,SPTBN4,SRI,TESC,TRDN"} {"GO.ID":"GO:0050867","Term":"positive regulation of cell activation","Annotated":324,"Significant":55,"Expected":19.57,"Rank in p.value_classic":77,"p.value_elim":0.05031,"p.value_classic":2.1e-12,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CD83,CYLD,GPR183,HAVCR1,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL15RA,IL4I1,IL7,JAK2,KARS1,KITLG,KLRK1,LILRA2,LRRK2,LYN,NOD2,NR4A3,PDCD1LG2,PLEK,RIPK2,SLAMF1,SOCS1,STAP1,TBX21,TICAM2,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:0001932","Term":"regulation of protein phosphorylation","Annotated":768,"Significant":73,"Expected":46.38,"Rank in p.value_classic":347,"p.value_elim":0.05049,"p.value_classic":0.00007,"genes":"AGT,BANK1,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MMD,MMP9,MVP,NCF1,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PID1,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,RIPK2,SLC11A1,SOCS1,SPTBN4,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0010965","Term":"regulation of mitotic sister chromatid separation","Annotated":57,"Significant":10,"Expected":3.44,"Rank in p.value_classic":547,"p.value_elim":0.0507,"p.value_classic":0.00198,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0046777","Term":"protein autophosphorylation","Annotated":170,"Significant":16,"Expected":10.27,"Rank in p.value_classic":1130,"p.value_elim":0.05079,"p.value_classic":0.05174,"genes":"AATK,ATP13A2,AURKB,CAMK2D,EPHB3,JAK2,LMTK2,LRRK2,LYN,MVP,NLRP12,PIM1,PRKX,TYRO3,VEGFC,VRK2"} {"GO.ID":"GO:0071260","Term":"cellular response to mechanical stimulus","Annotated":68,"Significant":8,"Expected":4.11,"Rank in p.value_classic":1121,"p.value_elim":0.05091,"p.value_classic":0.05153,"genes":"CD40,FAS,IRF1,KCNJ2,PTGER4,TLR5,TLR7,TLR8"} {"GO.ID":"GO:0032677","Term":"regulation of interleukin-8 production","Annotated":68,"Significant":8,"Expected":4.11,"Rank in p.value_classic":1122,"p.value_elim":0.05091,"p.value_classic":0.05153,"genes":"CD74,FCN1,KLF4,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"GO.ID":"GO:0032637","Term":"interleukin-8 production","Annotated":68,"Significant":8,"Expected":4.11,"Rank in p.value_classic":1123,"p.value_elim":0.05091,"p.value_classic":0.05153,"genes":"CD74,FCN1,KLF4,LILRA2,NOD2,TLR5,TLR7,TLR8"} {"GO.ID":"GO:0008038","Term":"neuron recognition","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1124,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"EPHB3,NRCAM,NRP1,PCDH12,TNFRSF21"} {"GO.ID":"GO:0042304","Term":"regulation of fatty acid biosynthetic process","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1125,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"BRCA1,CD74,CEACAM1,PDK4,SLC45A3"} {"GO.ID":"GO:0046006","Term":"regulation of activated T cell proliferation","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1126,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"BTN2A2,CD274,IL12RB1,PDCD1LG2,SLAMF1"} {"GO.ID":"GO:0086091","Term":"regulation of heart rate by cardiac conduction","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1127,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0007143","Term":"female meiotic nuclear division","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1128,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"DAZL,MEIKIN,NCAPH,NDC80,TOP2A"} {"GO.ID":"GO:0019432","Term":"triglyceride biosynthetic process","Annotated":34,"Significant":5,"Expected":2.05,"Rank in p.value_classic":1129,"p.value_elim":0.05114,"p.value_classic":0.0516,"genes":"ACSL1,C3,DGAT2,GK,PNPLA3"} {"GO.ID":"GO:0044092","Term":"negative regulation of molecular function","Annotated":583,"Significant":45,"Expected":35.21,"Rank in p.value_classic":1136,"p.value_elim":0.05123,"p.value_classic":0.053,"genes":"ACOD1,ADORA3,AGT,AIM2,AOC3,AURKB,B2M,CAMK2D,CARD16,CEACAM1,CRHBP,CYLD,DAB2,DEPTOR,DTNBP1,DTX3L,E2F1,IFIT2,JAK2,KCNE5,KLF4,KLRK1,LAMP3,LRP5,LRRK2,LYN,MAD2L1,MMP9,MVP,NLRC5,NLRP12,PARP10,PARP3,PARP9,PIM1,PKIB,PPM1E,RALB,SERPING1,SRI,STMN1,TRDN,WARS1,XIRP1,ZC3H12A"} {"GO.ID":"GO:0042391","Term":"regulation of membrane potential","Annotated":308,"Significant":26,"Expected":18.6,"Rank in p.value_classic":1135,"p.value_elim":0.05136,"p.value_classic":0.05265,"genes":"ANK2,ASIC1,ATP1B2,CAMK2D,CTNS,CXADR,EDN1,GABRA3,GHRL,GRIN3A,INSYN2A,KCNE5,KCNJ10,KCNJ2,LRRK2,NRCAM,P2RX4,P2RX7,PID1,PMAIP1,SCN4B,SRI,STX1A,SYNE1,TRDN,USP53"} {"GO.ID":"GO:0008285","Term":"negative regulation of cell population proliferation","Annotated":570,"Significant":53,"Expected":34.43,"Rank in p.value_classic":496,"p.value_elim":0.0514,"p.value_classic":0.0011,"genes":"ADORA3,APPL2,ASCL2,ATF5,B2M,BCL6,BTN2A2,CCL8,CD274,CD80,CDC6,CDH5,CDKN2C,CEACAM1,CTLA4,DAB2,DLL1,E2F1,GHRL,HLA-DRB1,HLA-E,HLA-G,IDO1,IFI35,IFIT3,IFITM1,IL12A,IL4I1,IRF1,JAK2,KLF4,LTA,LYN,MIR503,MTSS1,NMI,NPR1,OSM,OVOL1,PARP10,PDCD1LG2,PLAAT4,PML,PTPRU,RAPGEF2,SCIN,SSTR2,STAT1,TESC,TNFRSF14,TNFRSF21,TSPAN32,WARS1"} {"GO.ID":"GO:0051937","Term":"catecholamine transport","Annotated":45,"Significant":6,"Expected":2.72,"Rank in p.value_classic":1131,"p.value_elim":0.05155,"p.value_classic":0.05208,"genes":"ADORA3,DTNBP1,STX1A,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0031103","Term":"axon regeneration","Annotated":45,"Significant":6,"Expected":2.72,"Rank in p.value_classic":1132,"p.value_elim":0.05155,"p.value_classic":0.05208,"genes":"DHFR,JAK2,KLF4,KREMEN1,RTN4RL1,SCARF1"} {"GO.ID":"GO:0045744","Term":"negative regulation of G protein-coupled receptor signaling pathway","Annotated":45,"Significant":6,"Expected":2.72,"Rank in p.value_classic":1133,"p.value_elim":0.05155,"p.value_classic":0.05208,"genes":"CCL5,NECAB2,PADI2,PDE4B,PLEK,STMN1"} {"GO.ID":"GO:1902533","Term":"positive regulation of intracellular signal transduction","Annotated":863,"Significant":81,"Expected":52.12,"Rank in p.value_classic":334,"p.value_elim":0.05181,"p.value_classic":0.00004,"genes":"ADAM8,AGT,APOL3,AURKB,BANK1,BCL2L11,BIRC5,CARD16,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD40,CD74,CLEC6A,CSF1,CTNS,CX3CR1,DAB2,EDA,EDN1,F2RL3,GADD45B,GAREM1,GHRL,GLIPR2,GPR183,HBEGF,HGF,HLA-DRB1,ICAM1,IFI35,IFIT5,IQGAP3,JAK2,KITLG,LITAF,LRRK2,LYN,MAD2L1,MCF2L,NCF1,NDC80,NECAB2,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OSM,P2RX4,P2RX7,PIM1,PMAIP1,PML,PYHIN1,RAPGEF2,RASGRF1,RIPK2,S100A13,SCIMP,SECTM1,SEPTIN4,SLAMF1,SLC20A1,STAMBPL1,TGM2,TICAM2,TIFA,TLR7,TNFAIP8L3,TNFRSF11A,TNFSF10,TRIM22,UBD,ZC3H12A"} {"GO.ID":"GO:0061082","Term":"myeloid leukocyte cytokine production","Annotated":48,"Significant":10,"Expected":2.9,"Rank in p.value_classic":450,"p.value_elim":0.05216,"p.value_classic":0.00049,"genes":"BCL6,CD74,HLA-G,LITAF,NOD2,NR4A3,P2RX7,RIPK2,TICAM2,TLR7"} {"GO.ID":"GO:1903047","Term":"mitotic cell cycle process","Annotated":694,"Significant":73,"Expected":41.91,"Rank in p.value_classic":247,"p.value_elim":0.05251,"p.value_classic":2e-06,"genes":"ABCB1,ANLN,APPL2,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CENPK,CHMP4C,CLSPN,CYP1A1,DTL,DYNLT1,E2F1,EDN1,EME1,EML4,FAM107A,GINS1,GTSE1,IQGAP3,KIF11,KIF18B,KIF23,KLF4,LRP5,MAD2L1,MCM2,MCM4,MCM6,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,ORC1,PARP3,PKMYT1,PML,PRC1,PSME1,PSME2,RRM2,SPC24,SPC25,STMN1,TACC2,TICRR,TK1,UBD,UHRF1,WDR62,WEE1,ZWINT"} {"GO.ID":"GO:0002443","Term":"leukocyte mediated immunity","Annotated":306,"Significant":59,"Expected":18.48,"Rank in p.value_classic":44,"p.value_elim":0.05279,"p.value_classic":9e-16,"genes":"B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD28,CD40,CD74,CD80,CEACAM1,CR1L,CSF2RB,CX3CR1,EXO1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL4I1,IRF7,JAK3,KLRK1,LAG3,LTA,LYN,NOD2,NR4A3,P2RX7,PARP3,RNF19B,RSAD2,S100A13,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF7,STAP1,TAP2,TBX21,TICAM2,TLR8,UNG"} {"GO.ID":"GO:0032760","Term":"positive regulation of tumor necrosis factor production","Annotated":93,"Significant":10,"Expected":5.62,"Rank in p.value_classic":1143,"p.value_elim":0.05285,"p.value_classic":0.05359,"genes":"HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2"} {"GO.ID":"GO:0009612","Term":"response to mechanical stimulus","Annotated":171,"Significant":16,"Expected":10.33,"Rank in p.value_classic":1144,"p.value_elim":0.05305,"p.value_classic":0.05404,"genes":"CD40,CXCL10,EDN1,FAS,IRF1,KCNJ2,P2RX7,PKD1L3,PTGER4,STAT1,TIFAB,TLR5,TLR7,TLR8,TNFRSF11A,USP53"} {"GO.ID":"GO:0014046","Term":"dopamine secretion","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1137,"p.value_elim":0.05309,"p.value_classic":0.0535,"genes":"DTNBP1,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0002053","Term":"positive regulation of mesenchymal cell proliferation","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1138,"p.value_elim":0.05309,"p.value_classic":0.0535,"genes":"CHRD,LRP5,STAT1,SYNE1"} {"GO.ID":"GO:0010644","Term":"cell communication by electrical coupling","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1139,"p.value_elim":0.05309,"p.value_classic":0.0535,"genes":"ATP1B2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0031664","Term":"regulation of lipopolysaccharide-mediated signaling pathway","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1140,"p.value_elim":0.05309,"p.value_classic":0.0535,"genes":"ACOD1,CARD16,LILRA2,SCIMP"} {"GO.ID":"GO:0045742","Term":"positive regulation of epidermal growth factor receptor signaling pathway","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1141,"p.value_elim":0.05309,"p.value_classic":0.0535,"genes":"AGR2,AGT,MMP9,RALB"} {"GO.ID":"GO:0045597","Term":"positive regulation of cell differentiation","Annotated":712,"Significant":61,"Expected":43,"Rank in p.value_classic":608,"p.value_elim":0.05338,"p.value_classic":0.00341,"genes":"ADAM8,AGT,BCL6,BTN2A2,CD101,CD74,CD80,CD83,CDH5,CDS1,CEACAM1,CSF1,CX3CR1,CXCL9,CYLD,CYSLTR1,DAB1,DAB2,EDN1,EGR2,FAXDC2,GLIPR2,HAPLN3,HGF,HLA-DRA,HLA-DRB1,HLA-G,IFITM1,IL12RB1,IL15,IL15RA,IL4I1,IL7,JAK2,KITLG,LPL,LRP5,LTA,LYN,MMD,NRCAM,NRP1,PIM1,PLAAT4,PLXNA2,RAPGEF2,RIPK2,SCIN,SOCS1,SOX17,STAT1,TAL1,TESC,TGM2,TMEM119,TNFRSF11A,VCAN,VEGFC,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0030099","Term":"myeloid cell differentiation","Annotated":373,"Significant":40,"Expected":22.53,"Rank in p.value_classic":411,"p.value_elim":0.05388,"p.value_classic":0.00029,"genes":"ALAS1,B2M,BATF2,BATF3,BCL6,CD101,CD74,CEACAM1,CSF1,DLL1,EPAS1,FAXDC2,GPR183,HLA-DRB1,IL15,IL31RA,IRF4,IRF7,JAK2,KITLG,LILRB3,LYN,MAF,MMP9,NCAPG2,PML,PRKX,RELB,SBNO2,SCIN,SH3PXD2A,SNX10,SOCS1,STAT1,TAL1,TESC,TIFAB,TNFAIP6,TNFRSF11A,UBD"} {"GO.ID":"GO:0016447","Term":"somatic recombination of immunoglobulin gene segments","Annotated":57,"Significant":7,"Expected":3.44,"Rank in p.value_classic":1145,"p.value_elim":0.05408,"p.value_classic":0.05468,"genes":"BCL6,CD28,EXO1,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:0022612","Term":"gland morphogenesis","Annotated":106,"Significant":11,"Expected":6.4,"Rank in p.value_classic":1148,"p.value_elim":0.0541,"p.value_classic":0.0549,"genes":"CEACAM1,CSF1,EDA,FGL1,HGF,LRP5,NRP1,PML,POLB,RXFP1,TGM2"} {"GO.ID":"GO:0044773","Term":"mitotic DNA damage checkpoint signaling","Annotated":81,"Significant":9,"Expected":4.89,"Rank in p.value_classic":1146,"p.value_elim":0.05413,"p.value_classic":0.05484,"genes":"BRCA1,CDK1,CLSPN,DTL,EME1,GTSE1,MUC1,PML,TICRR"} {"GO.ID":"GO:0098661","Term":"inorganic anion transmembrane transport","Annotated":81,"Significant":9,"Expected":4.89,"Rank in p.value_classic":1147,"p.value_elim":0.05413,"p.value_classic":0.05484,"genes":"ANKH,ANO4,APOL1,CLIC5,GABRA3,OCA2,SLC12A3,SLC20A1,SLC37A1"} {"GO.ID":"GO:0042770","Term":"signal transduction in response to DNA damage","Annotated":185,"Significant":17,"Expected":11.17,"Rank in p.value_classic":1149,"p.value_elim":0.0543,"p.value_classic":0.05534,"genes":"BRCA1,CD74,CDK1,CLSPN,DTL,DTX3L,E2F1,EME1,FBXO6,GTSE1,MUC1,PARP9,PMAIP1,PML,PYHIN1,TICRR,WDR76"} {"GO.ID":"GO:0007188","Term":"adenylate cyclase-modulating G protein-coupled receptor signaling pathway","Annotated":145,"Significant":14,"Expected":8.76,"Rank in p.value_classic":1150,"p.value_elim":0.05444,"p.value_classic":0.05538,"genes":"ADGRE5,ADGRG5,CXCL10,CXCL11,CXCL9,EDN1,GNG2,GRM8,PDE4B,PTGER4,RAPGEF2,RXFP1,S1PR1,SSTR2"} {"GO.ID":"GO:0032680","Term":"regulation of tumor necrosis factor production","Annotated":145,"Significant":14,"Expected":8.76,"Rank in p.value_classic":1151,"p.value_elim":0.05444,"p.value_classic":0.05538,"genes":"CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:0032640","Term":"tumor necrosis factor production","Annotated":145,"Significant":14,"Expected":8.76,"Rank in p.value_classic":1152,"p.value_elim":0.05444,"p.value_classic":0.05538,"genes":"CX3CR1,GHRL,HLA-E,IFIH1,JAK2,LILRA2,LPL,LRRK2,NOD2,OAS2,OAS3,RIPK2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:0048469","Term":"cell maturation","Annotated":132,"Significant":13,"Expected":7.97,"Rank in p.value_classic":1153,"p.value_elim":0.05475,"p.value_classic":0.05565,"genes":"C3,DAZL,DMC1,EDN1,EPAS1,GLDN,IL15,LRRK2,NRCAM,SCARF1,SPTBN4,TAL1,TYMS"} {"GO.ID":"GO:0009615","Term":"response to virus","Annotated":347,"Significant":60,"Expected":20.96,"Rank in p.value_classic":65,"p.value_elim":0.05481,"p.value_classic":8.7e-14,"genes":"ACOD1,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,BATF3,CCL5,CCL8,CXCL10,CXCL9,DDX60,DTX3L,FGL2,GBP1,GBP2,GBP3,GBP5,GBP7,IFI27,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL27,IRF1,IRF7,ISG20,JAK2,NLRC5,NMI,OAS2,OAS3,PARP9,PLSCR1,PMAIP1,PML,RSAD2,RTP4,SERINC5,STAT1,STAT2,STMN1,TANK,TBX21,TLR7,TLR8,TRIM22,TRIM31,TSPAN32,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0007267","Term":"cell-cell signaling","Annotated":1264,"Significant":96,"Expected":76.34,"Rank in p.value_classic":747,"p.value_elim":0.0557,"p.value_classic":0.0102,"genes":"ADAM8,ADGRE5,ADORA3,AGT,AKAP7,AMER1,ANK2,ASIC1,CADPS2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD38,CELSR1,COLQ,CRHBP,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,DAB2,DKK2,DLGAP3,DLL1,DNM1,DTNBP1,DYSF,EDA,EDN1,EGR2,ERC2,EXOC3L1,FAM107A,GABRA3,GAL3ST4,GHRL,GJD3,GRIN3A,GRM8,HCAR2,HESX1,HGF,HLA-DRB1,HRH2,IL15,IL1RN,IL7,INA,INSYN2A,JAK2,KCNE5,KCNJ10,KLF4,KREMEN1,LRP5,LRRK2,LTA,LYN,MCTP2,MERTK,MYOF,NRP1,OSM,P2RX4,P2RX7,PRRT2,PTPRU,RAPGEF2,RASGRF1,RNF213,SCN4B,SIDT2,SLC16A10,SOX17,SRI,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYT1,SYT6,TGM2,TNFAIP6,TNFRSF11A,TNFSF10,TNFSF18,TNFSF8,TRABD2A,TSPAN32"} {"GO.ID":"GO:0140895","Term":"cell surface toll-like receptor signaling pathway","Annotated":61,"Significant":11,"Expected":3.68,"Rank in p.value_classic":490,"p.value_elim":0.05571,"p.value_classic":0.00095,"genes":"ACOD1,APPL2,IFI35,LILRA2,LYN,NMI,NOD2,RIPK2,SCIMP,TICAM2,TLR5"} {"GO.ID":"GO:0044839","Term":"cell cycle G2/M phase transition","Annotated":143,"Significant":17,"Expected":8.64,"Rank in p.value_classic":666,"p.value_elim":0.05593,"p.value_classic":0.00567,"genes":"ABCB1,ATF5,AURKB,BRCA1,CCNA2,CDC25A,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,NDC80,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0072330","Term":"monocarboxylic acid biosynthetic process","Annotated":159,"Significant":15,"Expected":9.6,"Rank in p.value_classic":1155,"p.value_elim":0.05632,"p.value_classic":0.05732,"genes":"ACOT4,BRCA1,CD74,CEACAM1,CYP1A1,DHRS9,DSE,EDN1,HSD3B7,IDO1,LPL,LTC4S,OSBPL6,PDK4,SLC45A3"} {"GO.ID":"GO:0032479","Term":"regulation of type I interferon production","Annotated":116,"Significant":17,"Expected":7.01,"Rank in p.value_classic":454,"p.value_elim":0.05647,"p.value_classic":0.00058,"genes":"ACOD1,CYLD,GBP7,IFIH1,IRF1,IRF7,NMI,OAS2,OAS3,RELB,RIPK2,STAT1,TANK,TICAM2,TLR7,TLR8,XAF1"} {"GO.ID":"GO:0032606","Term":"type I interferon production","Annotated":116,"Significant":17,"Expected":7.01,"Rank in p.value_classic":455,"p.value_elim":0.05647,"p.value_classic":0.00058,"genes":"ACOD1,CYLD,GBP7,IFIH1,IRF1,IRF7,NMI,OAS2,OAS3,RELB,RIPK2,STAT1,TANK,TICAM2,TLR7,TLR8,XAF1"} {"GO.ID":"GO:0060251","Term":"regulation of glial cell proliferation","Annotated":35,"Significant":5,"Expected":2.11,"Rank in p.value_classic":1156,"p.value_elim":0.05683,"p.value_classic":0.05734,"genes":"ASCL2,CYSLTR1,LTA,LYN,VEGFC"} {"GO.ID":"GO:0006301","Term":"postreplication repair","Annotated":35,"Significant":5,"Expected":2.11,"Rank in p.value_classic":1157,"p.value_elim":0.05683,"p.value_classic":0.05734,"genes":"BRCA1,DTL,PARP10,PCLAF,POLE2"} {"GO.ID":"GO:0007157","Term":"heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules","Annotated":35,"Significant":5,"Expected":2.11,"Rank in p.value_classic":1158,"p.value_elim":0.05683,"p.value_classic":0.05734,"genes":"CXADR,ICAM1,SCARF1,SELL,VCAM1"} {"GO.ID":"GO:0002920","Term":"regulation of humoral immune response","Annotated":28,"Significant":7,"Expected":1.69,"Rank in p.value_classic":497,"p.value_elim":0.05702,"p.value_classic":0.0011,"genes":"ACOD1,C3,CFH,CR1L,LTA,NOD2,SERPING1"} {"GO.ID":"GO:0051260","Term":"protein homooligomerization","Annotated":146,"Significant":14,"Expected":8.82,"Rank in p.value_classic":1174,"p.value_elim":0.05705,"p.value_classic":0.05802,"genes":"APPL2,ASIC1,B2M,COMP,DNM1,GBP5,GSDMD,HLA-G,KCNJ2,KCTD14,RIPK2,STEAP4,TIFA,TK1"} {"GO.ID":"GO:2000278","Term":"regulation of DNA biosynthetic process","Annotated":107,"Significant":11,"Expected":6.46,"Rank in p.value_classic":1175,"p.value_elim":0.05718,"p.value_classic":0.05802,"genes":"AURKB,CCNA2,CHTF18,DSCC1,GCH1,HGF,JADE2,KLF4,PARP3,PKIB,XRN1"} {"GO.ID":"GO:0043367","Term":"CD4-positive, alpha-beta T cell differentiation","Annotated":85,"Significant":20,"Expected":5.13,"Rank in p.value_classic":182,"p.value_elim":0.05749,"p.value_classic":1.1e-07,"genes":"ASCL2,BCL6,CD80,CD83,CTSL,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:1905153","Term":"regulation of membrane invagination","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1160,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"APPL2,C3,STAP1"} {"GO.ID":"GO:0035930","Term":"corticosteroid hormone secretion","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1161,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"AGT,DAB2,GHRL"} {"GO.ID":"GO:0030889","Term":"negative regulation of B cell proliferation","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1162,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"CTLA4,LYN,TNFRSF21"} {"GO.ID":"GO:0034122","Term":"negative regulation of toll-like receptor signaling pathway","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1163,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"CD300LF,IRF4,TYRO3"} {"GO.ID":"GO:2000318","Term":"positive regulation of T-helper 17 type immune response","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1164,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"CLEC6A,IL12RB1,JAK2"} {"GO.ID":"GO:1903729","Term":"regulation of plasma membrane organization","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1165,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"ATP8B1,CASP7,S100A10"} {"GO.ID":"GO:0030033","Term":"microvillus assembly","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1166,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"ATP8B1,FSCN1,RAPGEF2"} {"GO.ID":"GO:0006271","Term":"DNA strand elongation involved in DNA replication","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1167,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"GINS1,MCM4,MCM7"} {"GO.ID":"GO:0006206","Term":"pyrimidine nucleobase metabolic process","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1168,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"DPYS,TYMP,TYMS"} {"GO.ID":"GO:0060099","Term":"regulation of phagocytosis, engulfment","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1169,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"APPL2,C3,STAP1"} {"GO.ID":"GO:0035743","Term":"CD4-positive, alpha-beta T cell cytokine production","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1170,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"RSAD2,SLAMF1,TBX21"} {"GO.ID":"GO:0006878","Term":"intracellular copper ion homeostasis","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1171,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"MT2A,SCO2,SLC31A2"} {"GO.ID":"GO:0045869","Term":"negative regulation of single stranded viral RNA replication via double stranded DNA intermediate","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1172,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0046579","Term":"positive regulation of Ras protein signal transduction","Annotated":15,"Significant":3,"Expected":0.91,"Rank in p.value_classic":1173,"p.value_elim":0.0576,"p.value_classic":0.05796,"genes":"CSF1,KITLG,RASGRF1"} {"GO.ID":"GO:0030155","Term":"regulation of cell adhesion","Annotated":671,"Significant":85,"Expected":40.53,"Rank in p.value_classic":98,"p.value_elim":0.05782,"p.value_classic":3.7e-11,"genes":"ADAM8,AGR2,ASCL2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CEACAM1,CHRD,CSF1,CTLA4,CXCR3,CYLD,DAB1,DAB2,DLL1,EPHB3,FAM107A,FGL1,FGL2,GBP1,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL1RN,IL4I1,IL7,IRF1,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LYN,MDGA1,MIR503,MUC1,NOD2,NR4A3,NRP1,ONECUT2,PDCD1LG2,PDE3B,PLXNA2,PML,PRKX,PTPRU,RIPK2,RSU1,S100A10,S1PR1,SLAMF1,SOCS1,TBX21,TESC,TGM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:0048477","Term":"oogenesis","Annotated":70,"Significant":8,"Expected":4.23,"Rank in p.value_classic":1176,"p.value_elim":0.05864,"p.value_classic":0.05935,"genes":"DAZL,DMC1,EDN1,HORMAD1,NPM2,PAQR5,PAQR8,TNFAIP6"} {"GO.ID":"GO:1902807","Term":"negative regulation of cell cycle G1/S phase transition","Annotated":70,"Significant":8,"Expected":4.23,"Rank in p.value_classic":1177,"p.value_elim":0.05864,"p.value_classic":0.05935,"genes":"BTN2A2,FAM107A,GTSE1,KLF4,MIR503,MUC1,PML,WEE1"} {"GO.ID":"GO:0014070","Term":"response to organic cyclic compound","Annotated":681,"Significant":56,"Expected":41.13,"Rank in p.value_classic":770,"p.value_elim":0.05866,"p.value_classic":0.01108,"genes":"ACOD1,ACSL1,ALAS1,BCL2L11,BRCA1,CASP7,CCNA2,CD38,CD40,CD83,CDK1,COLEC12,CRHBP,CXCL10,CYP1A1,DAB2,DHFR,DTNBP1,EDN1,EPHX1,FAM107A,GNG2,GRAMD1B,IFIH1,IL1RN,JAK2,KITLG,KLF4,LBH,LRRK2,LYN,NCF1,NOD2,NR4A3,P2RX4,P2RX7,PADI2,PAQR8,PIM1,PMAIP1,PNPLA3,PTPRU,RALB,RAPGEF2,RIPK2,SLC12A3,SSTR2,STAT1,TGM2,THBD,TICAM2,TLR7,TNFRSF11A,TYMS,XRN1,ZC3H12A"} {"GO.ID":"GO:1903522","Term":"regulation of blood circulation","Annotated":184,"Significant":24,"Expected":11.11,"Rank in p.value_classic":412,"p.value_elim":0.05932,"p.value_classic":0.0003,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CXADR,CYSLTR1,EDN1,EPAS1,GCH1,GHRL,GJD3,HBEGF,HRH2,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SPTBN4,SRI,TRDN,ZC3H12A"} {"GO.ID":"GO:0045058","Term":"T cell selection","Annotated":47,"Significant":9,"Expected":2.84,"Rank in p.value_classic":539,"p.value_elim":0.05946,"p.value_classic":0.00175,"genes":"CD28,CD74,CTSL,CYLD,IL12RB1,IL15,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0015850","Term":"organic hydroxy compound transport","Annotated":201,"Significant":18,"Expected":12.14,"Rank in p.value_classic":1187,"p.value_elim":0.05975,"p.value_classic":0.06092,"genes":"ABCC11,ADORA3,AGT,ATP8B1,CEACAM1,DAB2,DTNBP1,EEPD1,GHRL,GRAMD1B,OSBPL6,SLC18A1,SOAT1,STX1A,SYT1,SYT6,TGM2,TTC39B"} {"GO.ID":"GO:0002428","Term":"antigen processing and presentation of peptide antigen via MHC class Ib","Annotated":14,"Significant":8,"Expected":0.85,"Rank in p.value_classic":210,"p.value_elim":0.05977,"p.value_classic":3.7e-07,"genes":"B2M,HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP2"} {"GO.ID":"GO:0002484","Term":"antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway","Annotated":13,"Significant":7,"Expected":0.79,"Rank in p.value_classic":263,"p.value_elim":0.05984,"p.value_classic":3.6e-06,"genes":"HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP2"} {"GO.ID":"GO:0002717","Term":"positive regulation of natural killer cell mediated immunity","Annotated":20,"Significant":7,"Expected":1.21,"Rank in p.value_classic":366,"p.value_elim":0.05987,"p.value_classic":0.00011,"genes":"HLA-E,HLA-F,HLA-G,IL12A,KLRK1,LAG3,SLAMF6"} {"GO.ID":"GO:0070671","Term":"response to interleukin-12","Annotated":12,"Significant":5,"Expected":0.72,"Rank in p.value_classic":444,"p.value_elim":0.05999,"p.value_classic":0.00044,"genes":"IL12A,IL12RB1,IL12RB2,JAK2,RIPK2"} {"GO.ID":"GO:0031589","Term":"cell-substrate adhesion","Annotated":313,"Significant":26,"Expected":18.9,"Rank in p.value_classic":1189,"p.value_elim":0.06005,"p.value_classic":0.06151,"genes":"AGR2,ANTXR1,ATP1B2,BCL2L11,BCL6,CSF1,DAB2,EDA,EPHB3,FAM107A,FGL1,GBP1,ITGA7,ITGB5,JAK2,LYVE1,MERTK,MIR503,NRP1,ONECUT2,PRKX,PXN,RSU1,S100A10,TYRO3,VCAM1"} {"GO.ID":"GO:0010876","Term":"lipid localization","Annotated":358,"Significant":35,"Expected":21.62,"Rank in p.value_classic":607,"p.value_elim":0.06027,"p.value_classic":0.00332,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,AGT,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,ATP8B1,C3,CDS1,CEACAM1,DAB2,DGAT2,EDN1,EEPD1,GHRL,GRAMD1B,LPL,OSBPL6,P2RX4,P2RX7,PLSCR1,PLSCR4,RBP7,RNF213,SOAT1,TNFAIP8L3,TNFRSF11A,TTC39B,XKR6,ZC3H12A"} {"GO.ID":"GO:1902914","Term":"regulation of protein polyubiquitination","Annotated":25,"Significant":4,"Expected":1.51,"Rank in p.value_classic":1183,"p.value_elim":0.0603,"p.value_classic":0.06076,"genes":"NMI,NOD2,PARP10,RIPK2"} {"GO.ID":"GO:0014808","Term":"release of sequestered calcium ion into cytosol by sarcoplasmic reticulum","Annotated":25,"Significant":4,"Expected":1.51,"Rank in p.value_classic":1184,"p.value_elim":0.0603,"p.value_classic":0.06076,"genes":"ANK2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0040020","Term":"regulation of meiotic nuclear division","Annotated":25,"Significant":4,"Expected":1.51,"Rank in p.value_classic":1185,"p.value_elim":0.0603,"p.value_classic":0.06076,"genes":"DAZL,HORMAD1,NPM2,ZWINT"} {"GO.ID":"GO:1903514","Term":"release of sequestered calcium ion into cytosol by endoplasmic reticulum","Annotated":25,"Significant":4,"Expected":1.51,"Rank in p.value_classic":1186,"p.value_elim":0.0603,"p.value_classic":0.06076,"genes":"ANK2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0002040","Term":"sprouting angiogenesis","Annotated":121,"Significant":12,"Expected":7.31,"Rank in p.value_classic":1190,"p.value_elim":0.0606,"p.value_classic":0.06153,"genes":"CEACAM1,DLL1,E2F2,E2F8,GHRL,GLUL,IL12A,KLF4,MIR503,NRP1,RNF213,VEGFC"} {"GO.ID":"GO:0048660","Term":"regulation of smooth muscle cell proliferation","Annotated":121,"Significant":12,"Expected":7.31,"Rank in p.value_classic":1191,"p.value_elim":0.0606,"p.value_classic":0.06153,"genes":"CCL5,EDN1,HBEGF,IL12A,JAK2,KLF4,MIR503,MMP9,NPR1,NR4A3,S1PR1,STAT1"} {"GO.ID":"GO:2000179","Term":"positive regulation of neural precursor cell proliferation","Annotated":47,"Significant":6,"Expected":2.84,"Rank in p.value_classic":1193,"p.value_elim":0.06151,"p.value_classic":0.06213,"genes":"CX3CR1,HAPLN3,LYN,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0051289","Term":"protein homotetramerization","Annotated":47,"Significant":6,"Expected":2.84,"Rank in p.value_classic":1194,"p.value_elim":0.06151,"p.value_classic":0.06213,"genes":"APPL2,B2M,DNM1,GBP5,KCNJ2,TK1"} {"GO.ID":"GO:0051785","Term":"positive regulation of nuclear division","Annotated":47,"Significant":6,"Expected":2.84,"Rank in p.value_classic":1195,"p.value_elim":0.06151,"p.value_classic":0.06213,"genes":"CD28,DAZL,EDN1,LRP5,NPM2,NUSAP1"} {"GO.ID":"GO:0002360","Term":"T cell lineage commitment","Annotated":29,"Significant":7,"Expected":1.75,"Rank in p.value_classic":516,"p.value_elim":0.06166,"p.value_classic":0.00138,"genes":"CTSL,CYLD,IL12RB1,IL7,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0036336","Term":"dendritic cell migration","Annotated":29,"Significant":7,"Expected":1.75,"Rank in p.value_classic":517,"p.value_elim":0.06166,"p.value_classic":0.00138,"genes":"ASB2,CCL5,GPR183,IL12A,NLRP12,SLAMF1,SLAMF8"} {"GO.ID":"GO:0050801","Term":"monoatomic ion homeostasis","Annotated":466,"Significant":46,"Expected":28.14,"Rank in p.value_classic":466,"p.value_elim":0.06198,"p.value_classic":0.00067,"genes":"AGT,ANK2,ANKH,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,EPAS1,ERC2,F2RL3,FAM20A,KCNJ10,KCNJ2,LRRK2,LYN,MT2A,NPR1,OCA2,P2RX7,PDK4,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC12A3,SLC31A2,SLC4A7,SNX10,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0045055","Term":"regulated exocytosis","Annotated":180,"Significant":20,"Expected":10.87,"Rank in p.value_classic":690,"p.value_elim":0.06201,"p.value_classic":0.00611,"genes":"CADPS2,CEACAM1,CRHBP,DTNBP1,ERC2,HLA-F,LRRK2,LYN,NR4A3,P2RX7,PLEK,PRRT2,S100A13,SCIN,STX11,STX1A,SV2B,SYNGR3,SYT1,SYT6"} {"GO.ID":"GO:0010559","Term":"regulation of glycoprotein biosynthetic process","Annotated":36,"Significant":5,"Expected":2.17,"Rank in p.value_classic":1199,"p.value_elim":0.06287,"p.value_classic":0.06342,"genes":"HBEGF,IL15,JAK3,NECAB2,SOAT1"} {"GO.ID":"GO:0010043","Term":"response to zinc ion","Annotated":36,"Significant":5,"Expected":2.17,"Rank in p.value_classic":1200,"p.value_elim":0.06287,"p.value_classic":0.06342,"genes":"ATP13A2,MT2A,P2RX4,P2RX7,VCAM1"} {"GO.ID":"GO:0002673","Term":"regulation of acute inflammatory response","Annotated":36,"Significant":5,"Expected":2.17,"Rank in p.value_classic":1201,"p.value_elim":0.06287,"p.value_classic":0.06342,"genes":"ADAM8,C3,HLA-E,OSM,TNFRSF11A"} {"GO.ID":"GO:0051100","Term":"negative regulation of binding","Annotated":96,"Significant":10,"Expected":5.8,"Rank in p.value_classic":1204,"p.value_elim":0.063,"p.value_classic":0.06386,"genes":"AURKB,B2M,CARD16,DAB2,E2F1,IFIT2,JAK2,LRRK2,RALB,XIRP1"} {"GO.ID":"GO:0042632","Term":"cholesterol homeostasis","Annotated":59,"Significant":7,"Expected":3.56,"Rank in p.value_classic":1203,"p.value_elim":0.06304,"p.value_classic":0.06373,"genes":"DGAT2,G6PC1,GRAMD1B,LPL,LRP5,SOAT1,TTC39B"} {"GO.ID":"GO:0043549","Term":"regulation of kinase activity","Annotated":460,"Significant":36,"Expected":27.78,"Rank in p.value_classic":1208,"p.value_elim":0.06415,"p.value_classic":0.06601,"genes":"AGT,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CEACAM1,CLSPN,CSF1,DEPTOR,DTNBP1,EDN1,HLA-DRB1,JAK2,LRP5,LRRK2,LYN,MERTK,MMD,MVP,NCF1,NLRC5,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,SLAMF8,SLC11A1,TNFRSF11A,TYRO3,WARS1"} {"GO.ID":"GO:0006885","Term":"regulation of pH","Annotated":84,"Significant":9,"Expected":5.07,"Rank in p.value_classic":1209,"p.value_elim":0.06532,"p.value_classic":0.06616,"genes":"ATP6V0D2,EDN1,LRRK2,OCA2,PDK4,RAB20,SLAMF8,SLC11A1,SLC4A7"} {"GO.ID":"GO:0006814","Term":"sodium ion transport","Annotated":149,"Significant":14,"Expected":9,"Rank in p.value_classic":1210,"p.value_elim":0.06536,"p.value_classic":0.06644,"genes":"ASIC1,ATP1B2,CAMK2D,EDN1,P2RX4,P2RX7,SCN4B,SLC12A3,SLC20A1,SLC4A7,SLC6A12,SPTBN4,TESC,TPCN1"} {"GO.ID":"GO:0019722","Term":"calcium-mediated signaling","Annotated":176,"Significant":16,"Expected":10.63,"Rank in p.value_classic":1211,"p.value_elim":0.06542,"p.value_classic":0.0666,"genes":"ANK2,CAMK2D,CCRL2,CX3CR1,CXCR3,EDN1,GBP1,LRRK2,MCOLN2,MCTP2,MYOZ2,P2RX4,P2RX7,PLEK,TPCN1,VCAM1"} {"GO.ID":"GO:0051306","Term":"mitotic sister chromatid separation","Annotated":60,"Significant":10,"Expected":3.62,"Rank in p.value_classic":591,"p.value_elim":0.06582,"p.value_classic":0.00293,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0048514","Term":"blood vessel morphogenesis","Annotated":534,"Significant":47,"Expected":32.25,"Rank in p.value_classic":678,"p.value_elim":0.0668,"p.value_classic":0.0059,"genes":"ADAM8,AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,COMP,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,EPAS1,EPHB3,GHRL,GLUL,HLA-G,IL12A,KLF4,LRP5,MIR503,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PML,PRKX,PROK2,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,STAT1,TAL1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:1900015","Term":"regulation of cytokine production involved in inflammatory response","Annotated":48,"Significant":6,"Expected":2.9,"Rank in p.value_classic":1212,"p.value_elim":0.06689,"p.value_classic":0.06755,"genes":"APPL2,GBP5,MEFV,NOD2,TICAM2,ZC3H12A"} {"GO.ID":"GO:0002534","Term":"cytokine production involved in inflammatory response","Annotated":48,"Significant":6,"Expected":2.9,"Rank in p.value_classic":1213,"p.value_elim":0.06689,"p.value_classic":0.06755,"genes":"APPL2,GBP5,MEFV,NOD2,TICAM2,ZC3H12A"} {"GO.ID":"GO:0010332","Term":"response to gamma radiation","Annotated":48,"Significant":6,"Expected":2.9,"Rank in p.value_classic":1214,"p.value_elim":0.06689,"p.value_classic":0.06755,"genes":"CCL7,CXCL10,PML,POLB,TMEM109,XRCC2"} {"GO.ID":"GO:0046686","Term":"response to cadmium ion","Annotated":48,"Significant":6,"Expected":2.9,"Rank in p.value_classic":1215,"p.value_elim":0.06689,"p.value_classic":0.06755,"genes":"CDK1,HESX1,MMP9,MT2A,NCF1,SLC11A1"} {"GO.ID":"GO:0051092","Term":"positive regulation of NF-kappaB transcription factor activity","Annotated":123,"Significant":12,"Expected":7.43,"Rank in p.value_classic":1218,"p.value_elim":0.06693,"p.value_classic":0.06794,"genes":"AGT,AIM2,CARD16,CD40,EDA,NOD2,RHEBL1,RIPK2,TICAM2,TNFRSF11A,TNFSF18,TRIM22"} {"GO.ID":"GO:0046425","Term":"regulation of receptor signaling pathway via JAK-STAT","Annotated":72,"Significant":8,"Expected":4.35,"Rank in p.value_classic":1216,"p.value_elim":0.06708,"p.value_classic":0.06787,"genes":"AGT,CCL5,DAB1,GBP7,JAK2,JAK3,PARP14,SOCS1"} {"GO.ID":"GO:0051262","Term":"protein tetramerization","Annotated":72,"Significant":8,"Expected":4.35,"Rank in p.value_classic":1217,"p.value_elim":0.06708,"p.value_classic":0.06787,"genes":"APPL2,B2M,DNM1,GBP5,HLA-DRB1,KCNJ2,RRM2,TK1"} {"GO.ID":"GO:0035239","Term":"tube morphogenesis","Annotated":744,"Significant":61,"Expected":44.93,"Rank in p.value_classic":731,"p.value_elim":0.06724,"p.value_classic":0.00874,"genes":"ADAM8,AGR2,AGT,AMOT,ASB2,BCL2L11,BRCA1,C3,CD40,CDH5,CEACAM1,CELSR1,COMP,CSF1,CTNS,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,DNAAF1,E2F2,E2F8,EDA,EDN1,EPAS1,EPHB3,GHRL,GLUL,HESX1,HLA-G,IFT122,IL12A,KLF4,LRP5,MICAL2,MIR503,MTSS1,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PML,PRKX,PROK2,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,STAT1,TAL1,TGM2,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0042430","Term":"indole-containing compound metabolic process","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1220,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"IDO1,IDO2,IL4I1"} {"GO.ID":"GO:1902074","Term":"response to salt","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1221,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"ANKH,DAB2,ZC3H12A"} {"GO.ID":"GO:0055093","Term":"response to hyperoxia","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1222,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"CYP1A1,FAS,POLB"} {"GO.ID":"GO:0045342","Term":"MHC class II biosynthetic process","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1223,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"CIITA,JAK2,SLC11A1"} {"GO.ID":"GO:2000561","Term":"regulation of CD4-positive, alpha-beta T cell proliferation","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1224,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"CD274,CD28,RIPK2"} {"GO.ID":"GO:0051590","Term":"positive regulation of neurotransmitter transport","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1225,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"DTNBP1,STX1A,SYT1"} {"GO.ID":"GO:0090026","Term":"positive regulation of monocyte chemotaxis","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1226,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"CCL5,CX3CR1,CXCL10"} {"GO.ID":"GO:0015721","Term":"bile acid and bile salt transport","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1227,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"ABCC11,ATP8B1,CEACAM1"} {"GO.ID":"GO:0035728","Term":"response to hepatocyte growth factor","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1228,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"APPL2,HGF,NRP1"} {"GO.ID":"GO:0035739","Term":"CD4-positive, alpha-beta T cell proliferation","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1229,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"CD274,CD28,RIPK2"} {"GO.ID":"GO:0045745","Term":"positive regulation of G protein-coupled receptor signaling pathway","Annotated":16,"Significant":3,"Expected":0.97,"Rank in p.value_classic":1230,"p.value_elim":0.06782,"p.value_classic":0.06824,"genes":"C3,EDN1,NECAB2"} {"GO.ID":"GO:0055092","Term":"sterol homeostasis","Annotated":60,"Significant":7,"Expected":3.62,"Rank in p.value_classic":1242,"p.value_elim":0.06785,"p.value_classic":0.06858,"genes":"DGAT2,G6PC1,GRAMD1B,LPL,LRP5,SOAT1,TTC39B"} {"GO.ID":"GO:0048524","Term":"positive regulation of viral process","Annotated":60,"Significant":7,"Expected":3.62,"Rank in p.value_classic":1243,"p.value_elim":0.06785,"p.value_classic":0.06858,"genes":"CCL5,CD28,CD74,GBP7,HLA-DRB1,TOP2A,TYRO3"} {"GO.ID":"GO:1901224","Term":"positive regulation of non-canonical NF-kappaB signal transduction","Annotated":60,"Significant":7,"Expected":3.62,"Rank in p.value_classic":1244,"p.value_elim":0.06785,"p.value_classic":0.06858,"genes":"EDA,EDN1,IFI35,NLRP12,NMI,NOD2,TLR7"} {"GO.ID":"GO:2001258","Term":"negative regulation of cation channel activity","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1231,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0044060","Term":"regulation of endocrine process","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1232,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"AGT,CRHBP,DAB2,GHRL"} {"GO.ID":"GO:0051954","Term":"positive regulation of amine transport","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1233,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"DTNBP1,P2RX7,STX1A,SYT1"} {"GO.ID":"GO:0060306","Term":"regulation of membrane repolarization","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1234,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"ANK2,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0090659","Term":"walking behavior","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1235,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"CTNS,DAB1,KCNJ10,SPTBN4"} {"GO.ID":"GO:0019985","Term":"translesion synthesis","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1236,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"DTL,PARP10,PCLAF,POLE2"} {"GO.ID":"GO:0070633","Term":"transepithelial transport","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1237,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"ABCB1,ABCG2,CXADR,EDN1"} {"GO.ID":"GO:2000273","Term":"positive regulation of signaling receptor activity","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1238,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"EDN1,JAK2,NCF1,NRP1"} {"GO.ID":"GO:0001778","Term":"plasma membrane repair","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1239,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"CASP7,CHMP4C,MYOF,S100A10"} {"GO.ID":"GO:1901186","Term":"positive regulation of ERBB signaling pathway","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1240,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"AGR2,AGT,MMP9,RALB"} {"GO.ID":"GO:0072525","Term":"pyridine-containing compound biosynthetic process","Annotated":26,"Significant":4,"Expected":1.57,"Rank in p.value_classic":1241,"p.value_elim":0.06801,"p.value_classic":0.06852,"genes":"IDO1,IDO2,PARP10,PARP9"} {"GO.ID":"GO:0009636","Term":"response to toxic substance","Annotated":177,"Significant":16,"Expected":10.69,"Rank in p.value_classic":1246,"p.value_elim":0.06811,"p.value_classic":0.06932,"genes":"ABCB1,ABCG2,AIFM2,CCL5,CDK1,CYP1A1,DHFR,EPHX1,GCH1,GSTK1,LTC4S,LYN,MT2A,PIM1,SLC11A1,TYMS"} {"GO.ID":"GO:1902749","Term":"regulation of cell cycle G2/M phase transition","Annotated":108,"Significant":14,"Expected":6.52,"Rank in p.value_classic":664,"p.value_elim":0.06884,"p.value_classic":0.0054,"genes":"ATF5,AURKB,BRCA1,CDC25A,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0007095","Term":"mitotic G2 DNA damage checkpoint signaling","Annotated":37,"Significant":5,"Expected":2.23,"Rank in p.value_classic":1248,"p.value_elim":0.06926,"p.value_classic":0.06986,"genes":"BRCA1,CDK1,CLSPN,DTL,TICRR"} {"GO.ID":"GO:0086009","Term":"membrane repolarization","Annotated":37,"Significant":5,"Expected":2.23,"Rank in p.value_classic":1249,"p.value_elim":0.06926,"p.value_classic":0.06986,"genes":"ANK2,ATP1B2,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0050864","Term":"regulation of B cell activation","Annotated":114,"Significant":17,"Expected":6.89,"Rank in p.value_classic":447,"p.value_elim":0.07006,"p.value_classic":0.00047,"genes":"BANK1,BCL6,CD28,CD38,CD74,CTLA4,CYLD,GPR183,IL4I1,IL7,LYN,NOD2,PARP3,SLAMF8,TBX21,TNFRSF21,TNFSF13B"} {"GO.ID":"GO:0048659","Term":"smooth muscle cell proliferation","Annotated":124,"Significant":12,"Expected":7.49,"Rank in p.value_classic":1250,"p.value_elim":0.07026,"p.value_classic":0.07131,"genes":"CCL5,EDN1,HBEGF,IL12A,JAK2,KLF4,MIR503,MMP9,NPR1,NR4A3,S1PR1,STAT1"} {"GO.ID":"GO:0030278","Term":"regulation of ossification","Annotated":98,"Significant":10,"Expected":5.92,"Rank in p.value_classic":1251,"p.value_elim":0.07043,"p.value_classic":0.07137,"genes":"ANKH,COMP,CSF1,DHRS3,EGR2,KREMEN1,P2RX7,PTGER4,S1PR1,TMEM119"} {"GO.ID":"GO:0051209","Term":"release of sequestered calcium ion into cytosol","Annotated":98,"Significant":10,"Expected":5.92,"Rank in p.value_classic":1252,"p.value_elim":0.07043,"p.value_classic":0.07137,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX7,SRI,TRDN"} {"GO.ID":"GO:0006836","Term":"neurotransmitter transport","Annotated":156,"Significant":18,"Expected":9.42,"Rank in p.value_classic":692,"p.value_elim":0.07046,"p.value_classic":0.00614,"genes":"ASIC1,CADPS2,DTNBP1,DYSF,ERC2,KCNJ10,LRRK2,MCTP2,MYOF,P2RX7,PRRT2,SLC18A1,SLC6A12,STX11,STX1A,SV2B,SYNGR3,SYT1"} {"GO.ID":"GO:0033002","Term":"muscle cell proliferation","Annotated":178,"Significant":16,"Expected":10.75,"Rank in p.value_classic":1254,"p.value_elim":0.07087,"p.value_classic":0.07213,"genes":"CCL5,CDK1,EDN1,HBEGF,HGF,IL12A,JAK2,KLF4,MIR503,MMP9,NDC80,NPR1,NR4A3,PIM1,S1PR1,STAT1"} {"GO.ID":"GO:1901987","Term":"regulation of cell cycle phase transition","Annotated":402,"Significant":50,"Expected":24.28,"Rank in p.value_classic":225,"p.value_elim":0.07115,"p.value_classic":8.4e-07,"genes":"ANLN,APPL2,ATF5,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CCNE2,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CHMP4C,CLSPN,CYP1A1,DTL,DTX3L,E2F1,EME1,FAM107A,FBXO6,GTSE1,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NPM2,NUF2,ORC1,OVOL1,PARP9,PKMYT1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TICRR,UBD,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0002366","Term":"leukocyte activation involved in immune response","Annotated":245,"Significant":42,"Expected":14.8,"Rank in p.value_classic":120,"p.value_elim":0.07123,"p.value_classic":6.7e-10,"genes":"ASCL2,BCL6,CD1C,CD28,CD74,CD80,CEACAM1,CX3CR1,DLL1,DYSF,EXO1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-F,ICAM1,IFI35,IL12RB1,IL27,IRF4,JAK3,KARS1,LILRA2,LYN,NMI,NR4A3,PARP3,PTGER4,RELB,RIPK2,S100A13,SBNO2,SLAMF1,SLAMF6,SLC11A1,SUCNR1,TBX21,TNFSF18,UNG,ZC3H12A"} {"GO.ID":"GO:0006261","Term":"DNA-templated DNA replication","Annotated":155,"Significant":27,"Expected":9.36,"Rank in p.value_classic":213,"p.value_elim":0.07152,"p.value_classic":5.5e-07,"genes":"BAZ1A,BCL6,BRCA1,CCNE2,CDC45,CDC6,CDT1,CHTF18,DSCC1,E2F8,EME1,FEN1,GINS1,GINS2,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,ORC1,POLB,POLE2,RECQL4,TICRR,TK1,TONSL"} {"GO.ID":"GO:0006576","Term":"biogenic amine metabolic process","Annotated":73,"Significant":8,"Expected":4.41,"Rank in p.value_classic":1255,"p.value_elim":0.07157,"p.value_classic":0.0724,"genes":"EPAS1,GCH1,IDO1,IDO2,IL4I1,NAAA,NPR1,SAT1"} {"GO.ID":"GO:0007186","Term":"G protein-coupled receptor signaling pathway","Annotated":554,"Significant":58,"Expected":33.46,"Rank in p.value_classic":319,"p.value_elim":0.07158,"p.value_classic":0.00003,"genes":"ADGRE5,ADGRG5,ADORA3,AGT,C3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CELSR1,CISH,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYSLTR1,CYSLTR2,DYNLT1,ECEL1,EDN1,F2RL3,FCN1,GHRL,GNG2,GPR183,GPR31,GRM8,HCAR2,HCAR3,HRH2,IGF2R,JAK2,LYN,NECAB2,NPR1,NXPH2,OR2I1P,P2RY14,PADI2,PDE3B,PDE4B,PLEK,PROK2,PTGER4,RAPGEF2,RGS18,RXFP1,S1PR1,SSTR2,STMN1,SUCNR1,TGM2,TYRO3"} {"GO.ID":"GO:0070372","Term":"regulation of ERK1 and ERK2 cascade","Annotated":230,"Significant":28,"Expected":13.89,"Rank in p.value_classic":416,"p.value_elim":0.07161,"p.value_classic":0.00031,"genes":"ATF3,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD74,CEACAM1,DAB2,GAREM1,GBP1,GLIPR2,GPR183,HLA-DRB1,ICAM1,LYN,MIR503,NECAB2,NLRP12,NOD2,NRP1,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3"} {"GO.ID":"GO:0006260","Term":"DNA replication","Annotated":266,"Significant":39,"Expected":16.07,"Rank in p.value_classic":199,"p.value_elim":0.07166,"p.value_classic":2.2e-07,"genes":"BAZ1A,BCL6,BRCA1,CCNA2,CCNE2,CDC25A,CDC45,CDC6,CDK1,CDT1,CHAF1B,CHTF18,DSCC1,DTL,E2F8,EME1,ESCO2,FAM111B,FEN1,GINS1,GINS2,JADE2,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,NPM2,ORC1,PCLAF,POLB,POLE2,RECQL4,RMI2,TICRR,TK1,TONSL,WEE1"} {"GO.ID":"GO:0042886","Term":"amide transport","Annotated":220,"Significant":19,"Expected":13.29,"Rank in p.value_classic":1260,"p.value_elim":0.07229,"p.value_classic":0.0737,"genes":"ABCB1,ABCG2,CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,STX1A,TAP1,TAP2"} {"GO.ID":"GO:0061005","Term":"cell differentiation involved in kidney development","Annotated":49,"Significant":6,"Expected":2.96,"Rank in p.value_classic":1256,"p.value_elim":0.07254,"p.value_classic":0.07324,"genes":"AMER1,EDN1,MMP9,MTSS1,PRKX,STAT1"} {"GO.ID":"GO:0002204","Term":"somatic recombination of immunoglobulin genes involved in immune response","Annotated":49,"Significant":6,"Expected":2.96,"Rank in p.value_classic":1257,"p.value_elim":0.07254,"p.value_classic":0.07324,"genes":"BCL6,CD28,EXO1,PARP3,TBX21,UNG"} {"GO.ID":"GO:0002208","Term":"somatic diversification of immunoglobulins involved in immune response","Annotated":49,"Significant":6,"Expected":2.96,"Rank in p.value_classic":1258,"p.value_elim":0.07254,"p.value_classic":0.07324,"genes":"BCL6,CD28,EXO1,PARP3,TBX21,UNG"} {"GO.ID":"GO:0045190","Term":"isotype switching","Annotated":49,"Significant":6,"Expected":2.96,"Rank in p.value_classic":1259,"p.value_elim":0.07254,"p.value_classic":0.07324,"genes":"BCL6,CD28,EXO1,PARP3,TBX21,UNG"} {"GO.ID":"GO:0051283","Term":"negative regulation of sequestering of calcium ion","Annotated":99,"Significant":10,"Expected":5.98,"Rank in p.value_classic":1262,"p.value_elim":0.07434,"p.value_classic":0.07533,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX7,SRI,TRDN"} {"GO.ID":"GO:0031668","Term":"cellular response to extracellular stimulus","Annotated":235,"Significant":20,"Expected":14.19,"Rank in p.value_classic":1263,"p.value_elim":0.0748,"p.value_classic":0.0763,"genes":"ATF3,CASTOR1,FAM107A,FAS,GLUL,GSDMD,KIF26A,LPL,LRRK2,LYN,MAP1LC3C,P2RX7,PDK4,PIM1,PMAIP1,RALB,SESN3,TNFRSF11A,VCAM1,ZC3H12A"} {"GO.ID":"GO:0001910","Term":"regulation of leukocyte mediated cytotoxicity","Annotated":73,"Significant":22,"Expected":4.41,"Rank in p.value_classic":109,"p.value_elim":0.07513,"p.value_classic":1.5e-10,"genes":"B2M,CD1A,CD1C,CEACAM1,CX3CR1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,SLAMF6,STAP1,TAP2"} {"GO.ID":"GO:1900744","Term":"regulation of p38MAPK cascade","Annotated":38,"Significant":5,"Expected":2.3,"Rank in p.value_classic":1264,"p.value_elim":0.07599,"p.value_classic":0.07664,"genes":"CYLD,GADD45B,HGF,NCF1,ZC3H12A"} {"GO.ID":"GO:0042908","Term":"xenobiotic transport","Annotated":38,"Significant":5,"Expected":2.3,"Rank in p.value_classic":1265,"p.value_elim":0.07599,"p.value_classic":0.07664,"genes":"ABCB1,ABCC11,ABCG2,ATP8B1,SLC18A1"} {"GO.ID":"GO:1990266","Term":"neutrophil migration","Annotated":104,"Significant":20,"Expected":6.28,"Rank in p.value_classic":259,"p.value_elim":0.07603,"p.value_classic":3.4e-06,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,MCOLN2,NOD2,PDE4B,SLAMF8,TNFAIP6"} {"GO.ID":"GO:0060326","Term":"cell chemotaxis","Annotated":252,"Significant":40,"Expected":15.22,"Rank in p.value_classic":155,"p.value_elim":0.0762,"p.value_classic":1.7e-08,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,GPR183,HBEGF,HGF,HSD3B7,IL12A,KLRK1,LYN,MTUS1,NOD2,NRP1,P2RX4,PADI2,PDE4B,S1PR1,SLAMF1,SLAMF8,STAP1,TNFAIP6,TNFRSF11A,VCAM1,VEGFC"} {"GO.ID":"GO:1901658","Term":"glycosyl compound catabolic process","Annotated":27,"Significant":4,"Expected":1.63,"Rank in p.value_classic":1266,"p.value_elim":0.07621,"p.value_classic":0.07677,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4"} {"GO.ID":"GO:0009268","Term":"response to pH","Annotated":27,"Significant":4,"Expected":1.63,"Rank in p.value_classic":1267,"p.value_elim":0.07621,"p.value_classic":0.07677,"genes":"ASIC1,CTSS,GPR31,PKD1L3"} {"GO.ID":"GO:0086019","Term":"cell-cell signaling involved in cardiac conduction","Annotated":27,"Significant":4,"Expected":1.63,"Rank in p.value_classic":1268,"p.value_elim":0.07621,"p.value_classic":0.07677,"genes":"ANK2,CXADR,KCNE5,SCN4B"} {"GO.ID":"GO:0032411","Term":"positive regulation of transporter activity","Annotated":74,"Significant":8,"Expected":4.47,"Rank in p.value_classic":1269,"p.value_elim":0.07623,"p.value_classic":0.07711,"genes":"ABCB1,ANK2,ATP1B2,CTSS,EDN1,SYNGR3,TESC,TRDN"} {"GO.ID":"GO:0006897","Term":"endocytosis","Annotated":621,"Significant":56,"Expected":37.51,"Rank in p.value_classic":533,"p.value_elim":0.07643,"p.value_classic":0.00163,"genes":"ANK2,APPL2,B2M,C2,C3,C4A,C4B,CD163,CD300LF,CD93,CEACAM1,CLEC10A,CLEC9A,COLEC12,CTSL,DAB2,DLL1,DNM1,DTNBP1,DYSF,ENPP2,FCN1,HAVCR1,IGF2R,IL15,IL15RA,ITSN1,LGALS3BP,LRP5,LRRK2,LY75,LYN,LYVE1,MERTK,MYO7B,NECAB2,NOD2,P2RX7,PLPP4,PLSCR1,RAB20,RALB,REPS2,SCARF1,SLAMF1,SLC11A1,SNX10,STAP1,STX1A,SYNE1,SYT1,TGM2,TICAM2,TPCN1,TYRO3,XKR6"} {"GO.ID":"GO:0050900","Term":"leukocyte migration","Annotated":320,"Significant":49,"Expected":19.33,"Rank in p.value_classic":129,"p.value_elim":0.07676,"p.value_classic":1.4e-09,"genes":"ADAM8,ASB2,ASCL2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,GPR183,HSD3B7,ICAM1,IL12A,ITGA7,KITLG,KLRK1,LYN,LYVE1,MCOLN2,MTUS1,NLRP12,NOD2,P2RX4,PADI2,PDE4B,PTGER4,S1PR1,SELL,SLAMF1,SLAMF8,STAP1,TBX21,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF18,VCAM1,VEGFC"} {"GO.ID":"GO:0098657","Term":"import into cell","Annotated":774,"Significant":66,"Expected":46.75,"Rank in p.value_classic":573,"p.value_elim":0.07727,"p.value_classic":0.00264,"genes":"ACSL1,ANK2,APPL2,ATP1B2,B2M,C2,C3,C4A,C4B,CD163,CD300LF,CD93,CEACAM1,CLEC10A,CLEC9A,COLEC12,CTSL,DAB2,DLL1,DNM1,DTNBP1,DYSF,ENPP2,FCN1,HAVCR1,IGF2R,IL15,IL15RA,ITSN1,KCNJ10,KCNJ15,KCNJ2,LGALS3BP,LRP5,LRRK2,LY75,LYN,LYVE1,MERTK,MYO7B,NECAB2,NOD2,P2RX7,PLPP4,PLSCR1,RAB20,RALB,REPS2,SCARF1,SLAMF1,SLC11A1,SLC12A3,SLC18A1,SLC2A5,SLC6A12,SNX10,STAP1,STX1A,SYNE1,SYNGR3,SYT1,TGM2,TICAM2,TPCN1,TYRO3,XKR6"} {"GO.ID":"GO:0070588","Term":"calcium ion transmembrane transport","Annotated":236,"Significant":20,"Expected":14.25,"Rank in p.value_classic":1272,"p.value_elim":0.07734,"p.value_classic":0.07888,"genes":"ANK2,ASIC1,CACNA2D3,CAMK2D,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,GRIN3A,LYN,MCOLN2,P2RX4,P2RX7,PDE4B,PKD1L3,PML,SRI,TPCN1,TRDN"} {"GO.ID":"GO:0002028","Term":"regulation of sodium ion transport","Annotated":62,"Significant":7,"Expected":3.74,"Rank in p.value_classic":1273,"p.value_elim":0.07809,"p.value_classic":0.07892,"genes":"ATP1B2,CAMK2D,P2RX4,P2RX7,SCN4B,SPTBN4,TESC"} {"GO.ID":"GO:0050886","Term":"endocrine process","Annotated":62,"Significant":7,"Expected":3.74,"Rank in p.value_classic":1274,"p.value_elim":0.07809,"p.value_classic":0.07892,"genes":"AGT,CRHBP,DAB2,EDN1,GHRL,HCAR2,SUCNR1"} {"GO.ID":"GO:0070534","Term":"protein K63-linked ubiquitination","Annotated":62,"Significant":7,"Expected":3.74,"Rank in p.value_classic":1275,"p.value_elim":0.07809,"p.value_classic":0.07892,"genes":"NOD2,PARP10,RIPK2,RNF213,TRIM22,TRIM31,UBE2T"} {"GO.ID":"GO:0016445","Term":"somatic diversification of immunoglobulins","Annotated":62,"Significant":7,"Expected":3.74,"Rank in p.value_classic":1276,"p.value_elim":0.07809,"p.value_classic":0.07892,"genes":"BCL6,CD28,EXO1,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:1900046","Term":"regulation of hemostasis","Annotated":50,"Significant":6,"Expected":3.02,"Rank in p.value_classic":1277,"p.value_elim":0.07844,"p.value_classic":0.0792,"genes":"CEACAM1,COMP,EDN1,ENPP4,SERPING1,THBD"} {"GO.ID":"GO:0043030","Term":"regulation of macrophage activation","Annotated":50,"Significant":6,"Expected":3.02,"Rank in p.value_classic":1278,"p.value_elim":0.07844,"p.value_classic":0.0792,"genes":"CD74,IL31RA,KARS1,LRRK2,STAP1,ZC3H12A"} {"GO.ID":"GO:0051341","Term":"regulation of oxidoreductase activity","Annotated":50,"Significant":6,"Expected":3.02,"Rank in p.value_classic":1279,"p.value_elim":0.07844,"p.value_classic":0.0792,"genes":"AGT,AOC3,DHFR,EDN1,GCH1,SLAMF8"} {"GO.ID":"GO:0048146","Term":"positive regulation of fibroblast proliferation","Annotated":50,"Significant":6,"Expected":3.02,"Rank in p.value_classic":1280,"p.value_elim":0.07844,"p.value_classic":0.0792,"genes":"AGT,CCNA2,CD74,CDC6,E2F1,PML"} {"GO.ID":"GO:0009223","Term":"pyrimidine deoxyribonucleotide catabolic process","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1282,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"DPYS,TYMP,UNG"} {"GO.ID":"GO:1902916","Term":"positive regulation of protein polyubiquitination","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1283,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"NMI,NOD2,RIPK2"} {"GO.ID":"GO:0006977","Term":"DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1284,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"GTSE1,MUC1,PML"} {"GO.ID":"GO:0034104","Term":"negative regulation of tissue remodeling","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1285,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"CD38,P2RX7,TMEM119"} {"GO.ID":"GO:0010996","Term":"response to auditory stimulus","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1286,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"CXCL10,TIFAB,USP53"} {"GO.ID":"GO:0071360","Term":"cellular response to exogenous dsRNA","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1287,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"COLEC12,IFIH1,RALB"} {"GO.ID":"GO:0031290","Term":"retinal ganglion cell axon guidance","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1288,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"EPHB3,NRCAM,NRP1"} {"GO.ID":"GO:0071294","Term":"cellular response to zinc ion","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1289,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"ATP13A2,MT2A,P2RX4"} {"GO.ID":"GO:2000831","Term":"regulation of steroid hormone secretion","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1290,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"AGT,DAB2,GHRL"} {"GO.ID":"GO:0002523","Term":"leukocyte migration involved in inflammatory response","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1291,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"ADAM8,SLAMF1,SLAMF8"} {"GO.ID":"GO:0071637","Term":"regulation of monocyte chemotactic protein-1 production","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1292,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"MCOLN2,NOD2,OAS3"} {"GO.ID":"GO:0071605","Term":"monocyte chemotactic protein-1 production","Annotated":17,"Significant":3,"Expected":1.03,"Rank in p.value_classic":1293,"p.value_elim":0.07881,"p.value_classic":0.07928,"genes":"MCOLN2,NOD2,OAS3"} {"GO.ID":"GO:0001773","Term":"myeloid dendritic cell activation","Annotated":26,"Significant":7,"Expected":1.57,"Rank in p.value_classic":470,"p.value_elim":0.07898,"p.value_classic":0.00068,"genes":"BATF2,BATF3,IRF4,RELB,SLAMF1,TSPAN32,UBD"} {"GO.ID":"GO:0098581","Term":"detection of external biotic stimulus","Annotated":21,"Significant":6,"Expected":1.27,"Rank in p.value_classic":507,"p.value_elim":0.0791,"p.value_classic":0.00118,"genes":"C4B,CLEC6A,HLA-A,HLA-B,HLA-DRB1,NOD2"} {"GO.ID":"GO:0008015","Term":"blood circulation","Annotated":385,"Significant":38,"Expected":23.25,"Rank in p.value_classic":545,"p.value_elim":0.07935,"p.value_classic":0.00192,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CDH5,CEACAM1,COMP,CXADR,CXCL10,CYSLTR1,DLL1,EDN1,EPAS1,ERAP2,GCH1,GHRL,GJD3,HBEGF,HRH2,KCNE5,KCNJ2,LRP5,MYOF,NPR1,P2RX4,PDE4B,SCN4B,SERPING1,SLC2A5,SPTBN4,SRI,STAT1,SUCNR1,TRDN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0071674","Term":"mononuclear cell migration","Annotated":165,"Significant":27,"Expected":9.97,"Rank in p.value_classic":246,"p.value_elim":0.07959,"p.value_classic":1.9e-06,"genes":"ADAM8,ASB2,ASCL2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CSF1,CX3CR1,CXCL10,CXCL11,GPR183,HSD3B7,ICAM1,IL12A,KLRK1,LYN,NLRP12,PADI2,S1PR1,SLAMF1,SLAMF8,TBX21,TNFRSF11A,TNFRSF14"} {"GO.ID":"GO:0051924","Term":"regulation of calcium ion transport","Annotated":181,"Significant":16,"Expected":10.93,"Rank in p.value_classic":1294,"p.value_elim":0.0796,"p.value_classic":0.08098,"genes":"ANK2,CAMK2D,CCL5,CXCL10,CXCL11,CXCL9,F2RL3,LILRA2,LYN,P2RX4,P2RX7,PDE4B,PLPP4,PML,SRI,TRDN"} {"GO.ID":"GO:0002699","Term":"positive regulation of immune effector process","Annotated":203,"Significant":38,"Expected":12.26,"Rank in p.value_classic":116,"p.value_elim":0.08003,"p.value_classic":3.3e-10,"genes":"APPL2,B2M,C3,CD1A,CD1C,CD28,CD74,CD80,DDX60,FCN1,HLA-A,HLA-B,HLA-C,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,KLRK1,LAG3,LTA,NOD2,NR4A3,P2RX7,RIPK2,RSAD2,SCIMP,SLAMF1,SLAMF6,STAP1,TAP2,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:0046879","Term":"hormone secretion","Annotated":223,"Significant":19,"Expected":13.47,"Rank in p.value_classic":1296,"p.value_elim":0.08018,"p.value_classic":0.08172,"genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,EXOC3L1,GHRL,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LYN,OSM,SIDT2,SLC16A10,SRI,STX1A"} {"GO.ID":"GO:0010389","Term":"regulation of G2/M transition of mitotic cell cycle","Annotated":98,"Significant":13,"Expected":5.92,"Rank in p.value_classic":679,"p.value_elim":0.08068,"p.value_classic":0.00593,"genes":"AURKB,BRCA1,CDC25A,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0006816","Term":"calcium ion transport","Annotated":309,"Significant":25,"Expected":18.66,"Rank in p.value_classic":1297,"p.value_elim":0.08145,"p.value_classic":0.08327,"genes":"ANK2,ASIC1,CACNA2D3,CAMK2D,CCL5,CCL8,CXCL10,CXCL11,CXCL9,CYSLTR1,EDN1,F2RL3,GRIN3A,LILRA2,LYN,MCOLN2,P2RX4,P2RX7,PDE4B,PKD1L3,PLPP4,PML,SRI,TPCN1,TRDN"} {"GO.ID":"GO:0051094","Term":"positive regulation of developmental process","Annotated":1089,"Significant":84,"Expected":65.77,"Rank in p.value_classic":768,"p.value_elim":0.08184,"p.value_classic":0.01101,"genes":"ADAM8,AGR2,AGT,AMOT,BCL6,BRCA1,BTN2A2,C21orf91,C3,CD101,CD28,CD40,CD74,CD80,CD83,CDH5,CDK1,CDS1,CEACAM1,CSF1,CX3CR1,CXCL9,CYLD,CYSLTR1,DAB1,DAB2,DLL1,EDN1,EGR2,ENPP2,EPHB3,FAXDC2,GHRL,GLIPR2,HAPLN3,HGF,HLA-DRA,HLA-DRB1,HLA-G,IFITM1,IL12RB1,IL15,IL15RA,IL4I1,IL7,IQGAP3,JAK2,KITLG,KLF4,LBH,LPL,LRP5,LTA,LYN,MMD,NRCAM,NRP1,P2RX7,PIM1,PLAAT4,PLXNA2,RAPGEF2,RIPK2,SCARF1,SCIN,SOCS1,SOX17,SPTBN4,SSBP3,STAT1,SYT1,TAL1,TBX21,TESC,TGM2,THBS2,TMEM119,TNFRSF11A,TNFSF13B,VCAN,VEGFC,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0051282","Term":"regulation of sequestering of calcium ion","Annotated":101,"Significant":10,"Expected":6.1,"Rank in p.value_classic":1298,"p.value_elim":0.08256,"p.value_classic":0.08363,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX7,SRI,TRDN"} {"GO.ID":"GO:0098754","Term":"detoxification","Annotated":101,"Significant":10,"Expected":6.1,"Rank in p.value_classic":1299,"p.value_elim":0.08256,"p.value_classic":0.08363,"genes":"ABCB1,ABCG2,AIFM2,DHFR,GCH1,GSTK1,LTC4S,MT2A,PIM1,SLC11A1"} {"GO.ID":"GO:0010508","Term":"positive regulation of autophagy","Annotated":141,"Significant":13,"Expected":8.52,"Rank in p.value_classic":1302,"p.value_elim":0.08288,"p.value_classic":0.08415,"genes":"CALCOCO2,DEPTOR,LRRK2,MEFV,NOD2,OPTN,RALB,RIPK2,RUFY4,SESN3,TPCN1,TRIM22,ZC3H12A"} {"GO.ID":"GO:0002437","Term":"inflammatory response to antigenic stimulus","Annotated":63,"Significant":11,"Expected":3.8,"Rank in p.value_classic":510,"p.value_elim":0.08291,"p.value_classic":0.00125,"genes":"C3,CD28,CYSLTR1,HLA-DRB1,HLA-E,IL1RN,IL31RA,KARS1,LTA,LYN,NOD2"} {"GO.ID":"GO:0015833","Term":"peptide transport","Annotated":196,"Significant":17,"Expected":11.84,"Rank in p.value_classic":1305,"p.value_elim":0.083,"p.value_classic":0.08448,"genes":"CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,STX1A,TAP1,TAP2"} {"GO.ID":"GO:0042398","Term":"cellular modified amino acid biosynthetic process","Annotated":39,"Significant":5,"Expected":2.36,"Rank in p.value_classic":1300,"p.value_elim":0.08306,"p.value_classic":0.08376,"genes":"CHAC1,DHFR,GCH1,GGT5,PLSCR1"} {"GO.ID":"GO:0035272","Term":"exocrine system development","Annotated":39,"Significant":5,"Expected":2.36,"Rank in p.value_classic":1301,"p.value_elim":0.08306,"p.value_classic":0.08376,"genes":"EDA,HGF,NRP1,POLB,TGM2"} {"GO.ID":"GO:1901990","Term":"regulation of mitotic cell cycle phase transition","Annotated":313,"Significant":39,"Expected":18.9,"Rank in p.value_classic":294,"p.value_elim":0.08325,"p.value_classic":0.00001,"genes":"ANLN,APPL2,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CCNE2,CDC25A,CDC6,CDCA5,CDK1,CDKN2C,CENPF,CHMP4C,CLSPN,CYP1A1,DTL,E2F1,FAM107A,GTSE1,KLF4,MAD2L1,MUC1,NDC80,NPM2,NUF2,ORC1,PKMYT1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TICRR,UBD,WEE1,ZWINT"} {"GO.ID":"GO:0043408","Term":"regulation of MAPK cascade","Annotated":529,"Significant":49,"Expected":31.95,"Rank in p.value_classic":541,"p.value_elim":0.08338,"p.value_classic":0.00181,"genes":"ADAM8,AGT,ATF3,BANK1,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CEACAM1,CYLD,DAB2,EDN1,FAS,GADD45B,GAREM1,GBP1,GHRL,GLIPR2,GPR183,HGF,HLA-DRB1,ICAM1,IQGAP3,JAK2,LBH,LRRK2,LYN,MIR503,NCF1,NECAB2,NLRP12,NOD2,NRK,NRP1,OSM,P2RX7,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3,TNFRSF11A,VRK2,ZC3H12A"} {"GO.ID":"GO:0086003","Term":"cardiac muscle cell contraction","Annotated":63,"Significant":7,"Expected":3.8,"Rank in p.value_classic":1303,"p.value_elim":0.08353,"p.value_classic":0.08441,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,PDE4B,SCN4B,SRI"} {"GO.ID":"GO:0045123","Term":"cellular extravasation","Annotated":63,"Significant":7,"Expected":3.8,"Rank in p.value_classic":1304,"p.value_elim":0.08353,"p.value_classic":0.08441,"genes":"ADAM8,CX3CR1,ICAM1,LYVE1,PTGER4,SELL,VCAM1"} {"GO.ID":"GO:0050727","Term":"regulation of inflammatory response","Annotated":313,"Significant":46,"Expected":18.9,"Rank in p.value_classic":156,"p.value_elim":0.0836,"p.value_classic":1.7e-08,"genes":"ACOD1,ADAM8,AGT,AIM2,BCL6,C3,CARD16,CASP4,CCL5,CD28,CDH5,CYLD,GHRL,GPR31,GSDMD,HGF,HLA-DRB1,HLA-E,IDO1,IFI35,IL15,IL22RA2,JAK2,KARS1,KLF4,LPL,LRRK2,LTA,LYN,MEFV,MMP9,NCF1,NLRP12,NMI,NOD2,OSM,PTGER4,SBNO2,SLAMF8,STAP1,SUCNR1,TLR7,TNFAIP6,TNFRSF11A,TYRO3,ZBP1"} {"GO.ID":"GO:0014009","Term":"glial cell proliferation","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1307,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"ASCL2,CSF1,CYSLTR1,LTA,LYN,VEGFC"} {"GO.ID":"GO:0050853","Term":"B cell receptor signaling pathway","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1308,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"BANK1,CD38,CTLA4,ITK,LYN,STAP1"} {"GO.ID":"GO:0031102","Term":"neuron projection regeneration","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1309,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"DHFR,JAK2,KLF4,KREMEN1,RTN4RL1,SCARF1"} {"GO.ID":"GO:0002886","Term":"regulation of myeloid leukocyte mediated immunity","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1310,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"C3,CX3CR1,HLA-E,LYN,STAP1,TICAM2"} {"GO.ID":"GO:0001836","Term":"release of cytochrome c from mitochondria","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1311,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"BCL2A1,BCL2L11,HGF,MMP9,PMAIP1,TNFSF10"} {"GO.ID":"GO:0006801","Term":"superoxide metabolic process","Annotated":51,"Significant":6,"Expected":3.08,"Rank in p.value_classic":1312,"p.value_elim":0.08461,"p.value_classic":0.08541,"genes":"DHFR,EDN1,GCH1,NCF1,NCF1C,SH3PXD2A"} {"GO.ID":"GO:0003044","Term":"regulation of systemic arterial blood pressure mediated by a chemical signal","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1313,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"AGT,EDN1,SLC2A5,SUCNR1"} {"GO.ID":"GO:0070296","Term":"sarcoplasmic reticulum calcium ion transport","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1314,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"ANK2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0034110","Term":"regulation of homotypic cell-cell adhesion","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1315,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"CCL5,CEACAM1,JAK2,LYN"} {"GO.ID":"GO:0043268","Term":"positive regulation of potassium ion transport","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1316,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"ANK2,ATP1B2,KCNE5,KCNJ2"} {"GO.ID":"GO:0071312","Term":"cellular response to alkaloid","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1317,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"CASP7,CCNA2,CRHBP,TGM2"} {"GO.ID":"GO:0034508","Term":"centromere complex assembly","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1318,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"CENPF,CENPK,HJURP,OIP5"} {"GO.ID":"GO:0042558","Term":"pteridine-containing compound metabolic process","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1319,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"DHFR,GCH1,MTHFD2,TYMS"} {"GO.ID":"GO:0046717","Term":"acid secretion","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1320,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"GHRL,HRH2,P2RX7,SNX10"} {"GO.ID":"GO:0006730","Term":"one-carbon metabolic process","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1321,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"CA11,DHFR,MTHFD2,TYMS"} {"GO.ID":"GO:1902882","Term":"regulation of response to oxidative stress","Annotated":28,"Significant":4,"Expected":1.69,"Rank in p.value_classic":1322,"p.value_elim":0.08487,"p.value_classic":0.08548,"genes":"AIFM2,DHFR,GCH1,SESN3"} {"GO.ID":"GO:0002263","Term":"cell activation involved in immune response","Annotated":249,"Significant":42,"Expected":15.04,"Rank in p.value_classic":126,"p.value_elim":0.08524,"p.value_classic":1.1e-09,"genes":"ASCL2,BCL6,CD1C,CD28,CD74,CD80,CEACAM1,CX3CR1,DLL1,DYSF,EXO1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-F,ICAM1,IFI35,IL12RB1,IL27,IRF4,JAK3,KARS1,LILRA2,LYN,NMI,NR4A3,PARP3,PTGER4,RELB,RIPK2,S100A13,SBNO2,SLAMF1,SLAMF6,SLC11A1,SUCNR1,TBX21,TNFSF18,UNG,ZC3H12A"} {"GO.ID":"GO:0050866","Term":"negative regulation of cell activation","Annotated":169,"Significant":33,"Expected":10.21,"Rank in p.value_classic":131,"p.value_elim":0.0857,"p.value_classic":1.6e-09,"genes":"ASCL2,BANK1,BCL6,BTN2A2,CD274,CD300LF,CD74,CD80,CEACAM1,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL31RA,IL4I1,IRF1,JAK3,LAG3,LYN,MERTK,PARP3,PDCD1LG2,SOCS1,TBX21,THBD,TNFRSF14,TNFRSF21,TSPAN32,TYRO3,ZC3H12A"} {"GO.ID":"GO:0002312","Term":"B cell activation involved in immune response","Annotated":76,"Significant":8,"Expected":4.59,"Rank in p.value_classic":1325,"p.value_elim":0.08609,"p.value_classic":0.08706,"genes":"BCL6,CD28,DLL1,EXO1,GPR183,PARP3,TBX21,UNG"} {"GO.ID":"GO:0031667","Term":"response to nutrient levels","Annotated":384,"Significant":30,"Expected":23.19,"Rank in p.value_classic":1328,"p.value_elim":0.08647,"p.value_classic":0.08859,"genes":"ACSL1,APPL2,ATF3,C2,CASTOR1,CD40,CXCL10,CYP1A1,FAM107A,FAS,GHRL,GLUL,IL15RA,LPL,LRRK2,LTA,MAP1LC3C,NOD2,PDK4,PIM1,PMAIP1,RALB,SESN3,SLC12A3,SSTR2,STAT1,TNFRSF11A,TYMS,VCAM1,ZC3H12A"} {"GO.ID":"GO:0002698","Term":"negative regulation of immune effector process","Annotated":97,"Significant":21,"Expected":5.86,"Rank in p.value_classic":202,"p.value_elim":0.08698,"p.value_classic":2.4e-07,"genes":"ASCL2,BCL6,CD80,CEACAM1,CR1L,CX3CR1,FGL2,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL4I1,JAK3,NOD2,PARP3,SERPING1,SLAMF1,SLAMF8,TBX21,ZC3H12A"} {"GO.ID":"GO:0008645","Term":"hexose transmembrane transport","Annotated":89,"Significant":9,"Expected":5.38,"Rank in p.value_classic":1326,"p.value_elim":0.08702,"p.value_classic":0.08807,"genes":"APPL2,C3,CTNS,EDN1,NR4A3,PID1,SLC2A5,SLC2A6,SLC45A3"} {"GO.ID":"GO:0000278","Term":"mitotic cell cycle","Annotated":824,"Significant":80,"Expected":49.77,"Rank in p.value_classic":296,"p.value_elim":0.08718,"p.value_classic":0.00001,"genes":"ABCB1,ANLN,APPL2,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CENPK,CHMP4C,CLSPN,CYLD,CYP1A1,DTL,DYNLT1,E2F1,E2F8,EDN1,EME1,EML4,FAM107A,GINS1,GTSE1,HGF,IQGAP3,KIF11,KIF15,KIF18B,KIF23,KLF4,LRP5,MAD2L1,MCM2,MCM4,MCM6,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,ORC1,OVOL1,PARP3,PKMYT1,PML,PRC1,PSME1,PSME2,RRM2,SPC24,SPC25,STMN1,TACC2,TAL1,TICRR,TK1,UBD,UHRF1,WDR62,WEE1,XRCC2,ZWINT"} {"GO.ID":"GO:0032409","Term":"regulation of transporter activity","Annotated":170,"Significant":15,"Expected":10.27,"Rank in p.value_classic":1329,"p.value_elim":0.08858,"p.value_classic":0.09003,"genes":"ABCB1,ANK2,ATP1B2,CAMK2D,CRHBP,CTSS,EDN1,KCNE5,MMP9,PIM1,SCN4B,SRI,SYNGR3,TESC,TRDN"} {"GO.ID":"GO:0002376","Term":"immune system process","Annotated":1988,"Significant":279,"Expected":120.07,"Rank in p.value_classic":2,"p.value_elim":0.08873,"genes":"ACOD1,ADAM8,ADGRE5,AIM2,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,ASB2,ASCL2,AURKB,B2M,BANK1,BATF2,BATF3,BCL2L11,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CD93,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CR1L,CSF1,CSF2RB,CTLA4,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DDX60,DLL1,DTX3L,DYSF,EDA,EDN1,ENPP2,EPAS1,EPHB3,ERAP2,EXO1,FAS,FAXDC2,FCN1,FGL1,FGL2,FYB1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR183,GPR31,GRAMD4,GSDMD,GTPBP1,H2BC21,HAVCR1,HCAR2,HELLS,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,HSD3B7,ICAM1,IDO1,IDO2,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IGSF6,IL12A,IL12RB1,IL15,IL15RA,IL18BP,IL1RN,IL27,IL31RA,IL32,IL4I1,IL7,IRF1,IRF4,IRF7,ISG20,ITGA7,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LAMP3,LILRA1,LILRA2,LILRB3,LITAF,LRP5,LRRK2,LTA,LY75,LYN,LYVE1,MCOLN2,MEFV,MERTK,MSRB1,MTUS1,NCAPG2,NCF1,NLRC5,NLRP12,NMI,NOD2,NR4A3,NUB1,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDCD1,PDCD1LG2,PDE4B,PLPP4,PLSCR1,PMAIP1,PML,POLB,PSMB10,PSMB8,PSMB9,PSME1,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,S100A13,S1PR1,SBNO2,SCIMP,SCIN,SECTM1,SELL,SERINC5,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,STAP1,STAT1,STAT2,SUCNR1,TAL1,TANK,TAP1,TAP2,TAPBP,TAPBPL,TBX21,TESC,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,UNG,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0034109","Term":"homotypic cell-cell adhesion","Annotated":76,"Significant":12,"Expected":4.59,"Rank in p.value_classic":544,"p.value_elim":0.08904,"p.value_classic":0.00189,"genes":"CCL5,CEACAM1,COMP,CXADR,F2RL3,FGL1,JAK2,LYN,PLEK,PTPRU,TSPAN32,TYRO3"} {"GO.ID":"GO:2000134","Term":"negative regulation of G1/S transition of mitotic cell cycle","Annotated":64,"Significant":7,"Expected":3.87,"Rank in p.value_classic":1330,"p.value_elim":0.08919,"p.value_classic":0.09011,"genes":"BTN2A2,FAM107A,GTSE1,KLF4,MUC1,PML,WEE1"} {"GO.ID":"GO:0015837","Term":"amine transport","Annotated":64,"Significant":7,"Expected":3.87,"Rank in p.value_classic":1331,"p.value_elim":0.08919,"p.value_classic":0.09011,"genes":"ADORA3,DTNBP1,P2RX7,SLC18A1,STX1A,SYT1,SYT6"} {"GO.ID":"GO:0046596","Term":"regulation of viral entry into host cell","Annotated":37,"Significant":9,"Expected":2.23,"Rank in p.value_classic":407,"p.value_elim":0.08921,"p.value_classic":0.00027,"genes":"CD74,CIITA,FCN1,HLA-DRB1,IFITM1,IFITM2,IFITM3,TRIM22,TRIM31"} {"GO.ID":"GO:0006468","Term":"protein phosphorylation","Annotated":1078,"Significant":91,"Expected":65.11,"Rank in p.value_classic":458,"p.value_elim":0.08963,"p.value_classic":0.00059,"genes":"AATK,AGT,ATP13A2,AURKB,BANK1,BIRC5,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,EPHB3,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JAK2,JAK3,KITLG,LIMK2,LMTK2,LRP5,LRRK2,LYN,MERTK,MMD,MMP9,MVP,NCF1,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PDK4,PID1,PIM1,PKIB,PKMYT1,PPM1E,PRKX,RALB,RAPGEF2,RIPK2,SLC11A1,SOCS1,SPTBN4,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC,VRK2,WARS1,WEE1,ZC3H12A"} {"GO.ID":"GO:0090068","Term":"positive regulation of cell cycle process","Annotated":219,"Significant":25,"Expected":13.23,"Rank in p.value_classic":532,"p.value_elim":0.09009,"p.value_classic":0.00162,"genes":"AURKB,BIRC5,CCNE2,CD28,CDC25A,CDC6,CDCA5,CDK1,CYP1A1,DAZL,DTL,E2F8,EDN1,FEN1,KIF23,LRP5,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUSAP1,PLSCR1,RRM2"} {"GO.ID":"GO:0010543","Term":"regulation of platelet activation","Annotated":40,"Significant":5,"Expected":2.42,"Rank in p.value_classic":1351,"p.value_elim":0.09046,"p.value_classic":0.09122,"genes":"CEACAM1,JAK2,LYN,PLEK,THBD"} {"GO.ID":"GO:1903018","Term":"regulation of glycoprotein metabolic process","Annotated":40,"Significant":5,"Expected":2.42,"Rank in p.value_classic":1352,"p.value_elim":0.09046,"p.value_classic":0.09122,"genes":"HBEGF,IL15,JAK3,NECAB2,SOAT1"} {"GO.ID":"GO:1902041","Term":"regulation of extrinsic apoptotic signaling pathway via death domain receptors","Annotated":40,"Significant":5,"Expected":2.42,"Rank in p.value_classic":1353,"p.value_elim":0.09046,"p.value_classic":0.09122,"genes":"ATF3,BRCA1,HGF,ICAM1,PMAIP1"} {"GO.ID":"GO:0061178","Term":"regulation of insulin secretion involved in cellular response to glucose stimulus","Annotated":40,"Significant":5,"Expected":2.42,"Rank in p.value_classic":1354,"p.value_elim":0.09046,"p.value_classic":0.09122,"genes":"GHRL,HLA-DRB1,LRP5,SIDT2,SRI"} {"GO.ID":"GO:0045143","Term":"homologous chromosome segregation","Annotated":40,"Significant":5,"Expected":2.42,"Rank in p.value_classic":1355,"p.value_elim":0.09046,"p.value_classic":0.09122,"genes":"CCNE2,DMC1,HORMAD1,MEIKIN,ZWINT"} {"GO.ID":"GO:0060307","Term":"regulation of ventricular cardiac muscle cell membrane repolarization","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1333,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"ANK2,KCNE5,SCN4B"} {"GO.ID":"GO:0060444","Term":"branching involved in mammary gland duct morphogenesis","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1334,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"CSF1,LRP5,PML"} {"GO.ID":"GO:0006910","Term":"phagocytosis, recognition","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1335,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"C4B,COLEC12,FCN1"} {"GO.ID":"GO:0010884","Term":"positive regulation of lipid storage","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1336,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"C3,LPL,ZC3H12A"} {"GO.ID":"GO:0050765","Term":"negative regulation of phagocytosis","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1337,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"CD300LF,DYSF,PLSCR1"} {"GO.ID":"GO:0007096","Term":"regulation of exit from mitosis","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1338,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"ANLN,CDCA5,NPM2"} {"GO.ID":"GO:0042438","Term":"melanin biosynthetic process","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1339,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"CTNS,OCA2,RAPGEF2"} {"GO.ID":"GO:0086012","Term":"membrane depolarization during cardiac muscle cell action potential","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1340,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"ANK2,KCNJ2,SCN4B"} {"GO.ID":"GO:0055070","Term":"copper ion homeostasis","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1341,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"MT2A,SCO2,SLC31A2"} {"GO.ID":"GO:0002755","Term":"MyD88-dependent toll-like receptor signaling pathway","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1342,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"CD300LF,IRF1,IRF7"} {"GO.ID":"GO:0050909","Term":"sensory perception of taste","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1343,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"ASIC1,PKD1L3,RTP4"} {"GO.ID":"GO:0032656","Term":"regulation of interleukin-13 production","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1344,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"HLA-E,IRF4,TNFRSF21"} {"GO.ID":"GO:0032616","Term":"interleukin-13 production","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1345,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"HLA-E,IRF4,TNFRSF21"} {"GO.ID":"GO:0002693","Term":"positive regulation of cellular extravasation","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1346,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"ADAM8,ICAM1,LYVE1"} {"GO.ID":"GO:1903779","Term":"regulation of cardiac conduction","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1347,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"AGT,ANK2,GJD3"} {"GO.ID":"GO:0098801","Term":"regulation of renal system process","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1348,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"AGT,EDN1,NPR1"} {"GO.ID":"GO:0071676","Term":"negative regulation of mononuclear cell migration","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1349,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"KLRK1,PADI2,SLAMF8"} {"GO.ID":"GO:0019433","Term":"triglyceride catabolic process","Annotated":18,"Significant":3,"Expected":1.09,"Rank in p.value_classic":1350,"p.value_elim":0.09051,"p.value_classic":0.09104,"genes":"LPL,PLB1,PNPLA3"} {"GO.ID":"GO:0002381","Term":"immunoglobulin production involved in immunoglobulin-mediated immune response","Annotated":52,"Significant":6,"Expected":3.14,"Rank in p.value_classic":1356,"p.value_elim":0.09104,"p.value_classic":0.0919,"genes":"BCL6,CD28,EXO1,PARP3,TBX21,UNG"} {"GO.ID":"GO:2001257","Term":"regulation of cation channel activity","Annotated":77,"Significant":8,"Expected":4.65,"Rank in p.value_classic":1358,"p.value_elim":0.09129,"p.value_classic":0.09231,"genes":"ANK2,CAMK2D,CTSS,EDN1,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0019915","Term":"lipid storage","Annotated":77,"Significant":8,"Expected":4.65,"Rank in p.value_classic":1359,"p.value_elim":0.09129,"p.value_classic":0.09231,"genes":"C3,CDS1,DGAT2,LPL,RNF213,SOAT1,TTC39B,ZC3H12A"} {"GO.ID":"GO:0033627","Term":"cell adhesion mediated by integrin","Annotated":77,"Significant":8,"Expected":4.65,"Rank in p.value_classic":1360,"p.value_elim":0.09129,"p.value_classic":0.09231,"genes":"CCL5,ICAM1,ITGA7,ITGB5,LYN,MUC1,PDE3B,TESC"} {"GO.ID":"GO:0006821","Term":"chloride transport","Annotated":77,"Significant":8,"Expected":4.65,"Rank in p.value_classic":1361,"p.value_elim":0.09129,"p.value_classic":0.09231,"genes":"ABCB1,ANO4,APOL1,ATP8B1,CLIC5,GABRA3,OCA2,SLC12A3"} {"GO.ID":"GO:0009914","Term":"hormone transport","Annotated":227,"Significant":19,"Expected":13.71,"Rank in p.value_classic":1363,"p.value_elim":0.09156,"p.value_classic":0.09326,"genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,EXOC3L1,GHRL,HCAR2,HLA-DRB1,IL1RN,JAK2,LRP5,LYN,OSM,SIDT2,SLC16A10,SRI,STX1A"} {"GO.ID":"GO:0015749","Term":"monosaccharide transmembrane transport","Annotated":90,"Significant":9,"Expected":5.44,"Rank in p.value_classic":1362,"p.value_elim":0.09182,"p.value_classic":0.09292,"genes":"APPL2,C3,CTNS,EDN1,NR4A3,PID1,SLC2A5,SLC2A6,SLC45A3"} {"GO.ID":"GO:0007052","Term":"mitotic spindle organization","Annotated":127,"Significant":15,"Expected":7.67,"Rank in p.value_classic":744,"p.value_elim":0.09224,"p.value_classic":0.00957,"genes":"AURKB,BIRC5,CHMP4C,KIF11,KIF23,MYBL2,NDC80,NUF2,PARP3,PRC1,SPC25,STMN1,TACC2,UHRF1,WDR62"} {"GO.ID":"GO:0010950","Term":"positive regulation of endopeptidase activity","Annotated":130,"Significant":12,"Expected":7.85,"Rank in p.value_classic":1364,"p.value_elim":0.09242,"p.value_classic":0.09373,"genes":"AIM2,FAS,GRAMD4,JAK2,LYN,MEFV,NLRP12,PMAIP1,PSME1,PSME2,RIPK2,TNFSF10"} {"GO.ID":"GO:0007584","Term":"response to nutrient","Annotated":130,"Significant":12,"Expected":7.85,"Rank in p.value_classic":1365,"p.value_elim":0.09242,"p.value_classic":0.09373,"genes":"ACSL1,C2,CD40,CXCL10,CYP1A1,LPL,LTA,NOD2,PIM1,STAT1,TYMS,VCAM1"} {"GO.ID":"GO:0050804","Term":"modulation of chemical synaptic transmission","Annotated":372,"Significant":29,"Expected":22.47,"Rank in p.value_classic":1373,"p.value_elim":0.09248,"p.value_classic":0.09467,"genes":"ADORA3,AKAP7,ASIC1,CD38,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GHRL,GRIN3A,GRM8,INA,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,PRRT2,RAPGEF2,RASGRF1,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0009755","Term":"hormone-mediated signaling pathway","Annotated":144,"Significant":13,"Expected":8.7,"Rank in p.value_classic":1374,"p.value_elim":0.09398,"p.value_classic":0.09538,"genes":"ACSL1,APPL2,BRCA1,CRHBP,DAB2,GHRL,JAK2,LBH,NR4A3,PADI2,PAQR8,RXFP1,SSTR2"} {"GO.ID":"GO:0090382","Term":"phagosome maturation","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1366,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"P2RX7,RAB20,SLAMF8,SLC4A7"} {"GO.ID":"GO:0039694","Term":"viral RNA genome replication","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1367,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,TOP2A"} {"GO.ID":"GO:0099622","Term":"cardiac muscle cell membrane repolarization","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1368,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"ANK2,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0002335","Term":"mature B cell differentiation","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1369,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"BCL6,DLL1,GPR183,SLAMF8"} {"GO.ID":"GO:0042554","Term":"superoxide anion generation","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1370,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"EDN1,NCF1,NCF1C,SH3PXD2A"} {"GO.ID":"GO:0090022","Term":"regulation of neutrophil chemotaxis","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1371,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"CD74,EDN1,NOD2,TNFAIP6"} {"GO.ID":"GO:0048679","Term":"regulation of axon regeneration","Annotated":29,"Significant":4,"Expected":1.75,"Rank in p.value_classic":1372,"p.value_elim":0.09399,"p.value_classic":0.09466,"genes":"KLF4,KREMEN1,RTN4RL1,SCARF1"} {"GO.ID":"GO:0099177","Term":"regulation of trans-synaptic signaling","Annotated":373,"Significant":29,"Expected":22.53,"Rank in p.value_classic":1378,"p.value_elim":0.09482,"p.value_classic":0.09705,"genes":"ADORA3,AKAP7,ASIC1,CD38,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GHRL,GRIN3A,GRM8,INA,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,PRRT2,RAPGEF2,RASGRF1,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0030001","Term":"metal ion transport","Annotated":597,"Significant":44,"Expected":36.06,"Rank in p.value_classic":1382,"p.value_elim":0.09487,"p.value_classic":0.09771,"genes":"ANK2,ASIC1,ATP1B2,B2M,CACNA2D3,CAMK2D,CCL5,CCL8,CXCL10,CXCL11,CXCL9,CYSLTR1,EDN1,F2RL3,FLVCR2,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LMTK2,LYN,MCOLN2,P2RX4,P2RX7,PDE4B,PKD1L3,PLPP4,PML,SCN4B,SLC11A1,SLC12A3,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SPTBN4,SRI,STEAP4,TESC,TPCN1,TRDN"} {"GO.ID":"GO:0016444","Term":"somatic cell DNA recombination","Annotated":65,"Significant":7,"Expected":3.93,"Rank in p.value_classic":1376,"p.value_elim":0.09505,"p.value_classic":0.09602,"genes":"BCL6,CD28,EXO1,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:0002562","Term":"somatic diversification of immune receptors via germline recombination within a single locus","Annotated":65,"Significant":7,"Expected":3.93,"Rank in p.value_classic":1377,"p.value_elim":0.09505,"p.value_classic":0.09602,"genes":"BCL6,CD28,EXO1,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:0010638","Term":"positive regulation of organelle organization","Annotated":462,"Significant":35,"Expected":27.9,"Rank in p.value_classic":1381,"p.value_elim":0.0951,"p.value_classic":0.0976,"genes":"AURKB,BCL2L11,CALCOCO2,CD28,CDK1,DAZL,EDN1,ERC2,FEN1,FSCN1,GCH1,LRP5,MMP9,MTSS1,NCAPG,NCAPG2,NCAPH,NOD2,NPM2,NRP1,NUSAP1,P2RX7,PKIB,PLEK,PMAIP1,PML,PPM1E,PRRT2,PXN,RALB,S100A10,SCIN,SYT1,TAL1,TNFSF10"} {"GO.ID":"GO:0051896","Term":"regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction","Annotated":200,"Significant":17,"Expected":12.08,"Rank in p.value_classic":1379,"p.value_elim":0.09551,"p.value_classic":0.09716,"genes":"ADAM8,AGT,AIM2,BANK1,BTN2A2,CCL5,CD28,CEACAM1,CX3CR1,HBEGF,HGF,HLA-G,JAK2,NCF1,OSM,P2RX4,SESN3"} {"GO.ID":"GO:0007346","Term":"regulation of mitotic cell cycle","Annotated":462,"Significant":49,"Expected":27.9,"Rank in p.value_classic":355,"p.value_elim":0.09578,"p.value_classic":0.00008,"genes":"ANLN,APPL2,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNE2,CD28,CDC25A,CDC6,CDCA5,CDK1,CDKN2C,CENPF,CHMP4C,CLSPN,CYLD,CYP1A1,DTL,E2F1,EDN1,EME1,FAM107A,GTSE1,KLF4,LRP5,MAD2L1,MKI67,MUC1,NDC80,NPM2,NUF2,NUSAP1,ORC1,OVOL1,PKMYT1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TAL1,TICRR,UBD,WEE1,ZWINT"} {"GO.ID":"GO:0051345","Term":"positive regulation of hydrolase activity","Annotated":403,"Significant":31,"Expected":24.34,"Rank in p.value_classic":1385,"p.value_elim":0.09597,"p.value_classic":0.09831,"genes":"AIM2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CTSL,CTSS,FAS,GRAMD4,ITK,JAK2,LYN,MEFV,NLRP12,PLEK,PMAIP1,PSME1,PSME2,RAPGEF2,RASGEF1C,RASGRF1,RIPK2,RSU1,S100A10,TANK,TGM2,TNFSF10,USP6NL"} {"GO.ID":"GO:0051259","Term":"protein complex oligomerization","Annotated":201,"Significant":20,"Expected":12.14,"Rank in p.value_classic":870,"p.value_elim":0.09652,"p.value_classic":0.01921,"genes":"APPL2,ASIC1,B2M,CD74,COMP,DNM1,GBP5,GSDMD,HLA-DRB1,HLA-G,IFIH1,KCNJ2,KCTD14,RIPK2,RRM2,STEAP4,SYT1,TIFA,TK1,ZC3H12A"} {"GO.ID":"GO:0072332","Term":"intrinsic apoptotic signaling pathway by p53 class mediator","Annotated":78,"Significant":8,"Expected":4.71,"Rank in p.value_classic":1383,"p.value_elim":0.09666,"p.value_classic":0.09773,"genes":"CD74,E2F1,E2F2,MUC1,PMAIP1,PML,TIFAB,TMEM109"} {"GO.ID":"GO:1904892","Term":"regulation of receptor signaling pathway via STAT","Annotated":78,"Significant":8,"Expected":4.71,"Rank in p.value_classic":1384,"p.value_elim":0.09666,"p.value_classic":0.09773,"genes":"AGT,CCL5,DAB1,GBP7,JAK2,JAK3,PARP14,SOCS1"} {"GO.ID":"GO:0030522","Term":"intracellular receptor signaling pathway","Annotated":312,"Significant":28,"Expected":18.84,"Rank in p.value_classic":898,"p.value_elim":0.09685,"p.value_classic":0.02326,"genes":"AURKB,BRCA1,COLEC12,CYLD,DAB2,DDX60,DHRS3,GBP2,GBP5,GRAMD4,IFIH1,IRF7,JAK2,LBH,MEFV,NOD2,NR4A3,OAS3,PADI2,PIM1,PML,RIPK2,RSAD2,SCIMP,TIFA,TLR7,TLR8,TRIM31"} {"GO.ID":"GO:0000076","Term":"DNA replication checkpoint signaling","Annotated":19,"Significant":6,"Expected":1.15,"Rank in p.value_classic":465,"p.value_elim":0.09774,"p.value_classic":0.00065,"genes":"CDC45,CDC6,CDT1,CLSPN,ORC1,TICRR"} {"GO.ID":"GO:2001233","Term":"regulation of apoptotic signaling pathway","Annotated":345,"Significant":27,"Expected":20.84,"Rank in p.value_classic":1396,"p.value_elim":0.09816,"p.value_classic":0.10036,"genes":"AGT,ATF3,BCL2L11,BCL2L14,BRCA1,CD74,CTSL,CTSS,CX3CR1,CYLD,DEPTOR,FAS,G0S2,HELLS,HGF,ICAM1,IL7,JAK2,LRRK2,MMP9,MUC1,NRP1,PMAIP1,PML,SEPTIN4,TIFAB,TNFSF10"} {"GO.ID":"GO:0140527","Term":"reciprocal homologous recombination","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1386,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"DMC1,EME1,RAD54B,RAD54L,TOP2A"} {"GO.ID":"GO:0060986","Term":"endocrine hormone secretion","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1387,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"AGT,CRHBP,DAB2,GHRL,HCAR2"} {"GO.ID":"GO:0007131","Term":"reciprocal meiotic recombination","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1388,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"DMC1,EME1,RAD54B,RAD54L,TOP2A"} {"GO.ID":"GO:0071868","Term":"cellular response to monoamine stimulus","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1389,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"DTNBP1,GNG2,LRRK2,NR4A3,TGM2"} {"GO.ID":"GO:0071870","Term":"cellular response to catecholamine stimulus","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1390,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"DTNBP1,GNG2,LRRK2,NR4A3,TGM2"} {"GO.ID":"GO:0035850","Term":"epithelial cell differentiation involved in kidney development","Annotated":41,"Significant":5,"Expected":2.48,"Rank in p.value_classic":1391,"p.value_elim":0.0982,"p.value_classic":0.099,"genes":"EDN1,MMP9,MTSS1,PRKX,STAT1"} {"GO.ID":"GO:0032943","Term":"mononuclear cell proliferation","Annotated":249,"Significant":45,"Expected":15.04,"Rank in p.value_classic":93,"p.value_elim":0.09841,"p.value_classic":2.6e-11,"genes":"BCL6,BTN2A2,BTN3A1,CCL5,CD274,CD28,CD38,CD40,CD74,CD80,CSF1,CTLA4,GPR183,HELLS,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,P2RX7,PDCD1LG2,PSMB10,RIPK2,SLAMF1,SLC11A1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:2000116","Term":"regulation of cysteine-type endopeptidase activity","Annotated":159,"Significant":14,"Expected":9.6,"Rank in p.value_classic":1394,"p.value_elim":0.0987,"p.value_classic":0.10021,"genes":"AIM2,CARD16,FAS,GRAMD4,JAK2,KLF4,LAMP3,MEFV,MMP9,NLRP12,PMAIP1,PSMB9,RIPK2,TNFSF10"} {"GO.ID":"GO:0022898","Term":"regulation of transmembrane transporter activity","Annotated":159,"Significant":14,"Expected":9.6,"Rank in p.value_classic":1395,"p.value_elim":0.0987,"p.value_classic":0.10021,"genes":"ABCB1,ANK2,ATP1B2,CAMK2D,CRHBP,CTSS,EDN1,KCNE5,MMP9,PIM1,SCN4B,SRI,TESC,TRDN"} {"GO.ID":"GO:0003158","Term":"endothelium development","Annotated":118,"Significant":11,"Expected":7.13,"Rank in p.value_classic":1393,"p.value_elim":0.09874,"p.value_classic":0.10006,"genes":"CDH5,CEACAM1,CXCL10,DLL1,EDN1,ICAM1,MARVELD2,NRP1,RAPGEF2,S1PR1,SOX17"} {"GO.ID":"GO:0051235","Term":"maintenance of location","Annotated":273,"Significant":22,"Expected":16.49,"Rank in p.value_classic":1399,"p.value_elim":0.10039,"p.value_classic":0.10238,"genes":"ANK2,C3,CAMK2D,CDS1,CXCL10,CXCL11,CXCL9,DGAT2,F2RL3,LPL,LYN,P2RX7,PML,RNF213,SCIN,SOAT1,SRI,SYNE1,TMSB10,TRDN,TTC39B,ZC3H12A"} {"GO.ID":"GO:2001251","Term":"negative regulation of chromosome organization","Annotated":91,"Significant":12,"Expected":5.5,"Rank in p.value_classic":728,"p.value_elim":0.1004,"p.value_classic":0.00842,"genes":"AURKB,BIRC5,BUB1B,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,TOP2A,XRN1,ZWINT"} {"GO.ID":"GO:0051208","Term":"sequestering of calcium ion","Annotated":105,"Significant":10,"Expected":6.34,"Rank in p.value_classic":1397,"p.value_elim":0.10061,"p.value_classic":0.10187,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX7,SRI,TRDN"} {"GO.ID":"GO:0000086","Term":"G2/M transition of mitotic cell cycle","Annotated":129,"Significant":15,"Expected":7.79,"Rank in p.value_classic":767,"p.value_elim":0.10094,"p.value_classic":0.01098,"genes":"ABCB1,AURKB,BRCA1,CCNA2,CDC25A,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,ORC1,PKMYT1,TICRR,WEE1"} {"GO.ID":"GO:0006942","Term":"regulation of striated muscle contraction","Annotated":66,"Significant":7,"Expected":3.99,"Rank in p.value_classic":1398,"p.value_elim":0.10112,"p.value_classic":0.10215,"genes":"ANK2,CAMK2D,KCNJ2,P2RX4,PDE4B,SRI,ZC3H12A"} {"GO.ID":"GO:0051240","Term":"positive regulation of multicellular organismal process","Annotated":1335,"Significant":143,"Expected":80.63,"Rank in p.value_classic":79,"p.value_elim":0.10121,"p.value_classic":2.4e-12,"genes":"ACSL1,ADAM8,AGT,AIM2,AMOT,APPL2,B2M,BCL6,BRCA1,BTN2A2,BTN3A1,BTN3A2,C3,CAMK2D,CCL5,CD101,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CLEC6A,CLEC9A,CSF1,CX3CR1,CYLD,CYSLTR1,DAB2,DLL1,EDN1,EGR2,ENPP4,EPAS1,EPHB3,FCN1,G0S2,GBP5,GCH1,GHRL,GLIPR2,GPR183,GSDMD,HAPLN3,HAVCR1,HCAR2,HGF,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL27,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLF4,KLRK1,LBH,LILRA2,LPL,LRRK2,LTA,LYN,MCOLN2,MEFV,NLRP12,NOD2,NPR1,NR4A3,NRP1,OAS2,OAS3,OSM,P2RX7,PDCD1LG2,PDE4B,PIM1,PLAAT4,PLEK,PLXNA2,PROK2,PTGER4,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,SPTBN4,STAP1,STAT1,TANK,TBX21,TESC,TGM2,THBD,THBS2,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF13B,VCAM1,VCAN,VEGFC,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0060078","Term":"regulation of postsynaptic membrane potential","Annotated":92,"Significant":9,"Expected":5.56,"Rank in p.value_classic":1400,"p.value_elim":0.10187,"p.value_classic":0.10307,"genes":"GABRA3,GHRL,GRIN3A,INSYN2A,LRRK2,P2RX4,P2RX7,STX1A,SYNE1"} {"GO.ID":"GO:1902107","Term":"positive regulation of leukocyte differentiation","Annotated":166,"Significant":22,"Expected":10.03,"Rank in p.value_classic":439,"p.value_elim":0.10213,"p.value_classic":0.00042,"genes":"ADAM8,BCL6,BTN2A2,CD101,CD74,CD80,CD83,CSF1,CYLD,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL4I1,IL7,KITLG,RIPK2,SOCS1,TESC,TNFRSF11A"} {"GO.ID":"GO:1903708","Term":"positive regulation of hemopoiesis","Annotated":166,"Significant":22,"Expected":10.03,"Rank in p.value_classic":440,"p.value_elim":0.10213,"p.value_classic":0.00042,"genes":"ADAM8,BCL6,BTN2A2,CD101,CD74,CD80,CD83,CSF1,CYLD,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL4I1,IL7,KITLG,RIPK2,SOCS1,TESC,TNFRSF11A"} {"GO.ID":"GO:0050865","Term":"regulation of cell activation","Annotated":522,"Significant":81,"Expected":31.53,"Rank in p.value_classic":47,"p.value_elim":0.10227,"p.value_classic":1.9e-15,"genes":"ADAM8,ASCL2,B2M,BANK1,BCL6,BTN2A2,CCL5,CD274,CD28,CD300LF,CD38,CD74,CD80,CD83,CEACAM1,CTLA4,CYLD,FGL1,FGL2,GPR183,HAVCR1,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LRRK2,LYN,MERTK,NOD2,NR4A3,PARP3,PDCD1LG2,PLEK,PLSCR1,RIPK2,SIT1,SLAMF1,SLAMF8,SOCS1,STAP1,TBX21,THBD,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,VCAM1,ZC3H12A"} {"GO.ID":"GO:0006658","Term":"phosphatidylserine metabolic process","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1401,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"PLA1A,PLSCR1,SERINC5"} {"GO.ID":"GO:1900016","Term":"negative regulation of cytokine production involved in inflammatory response","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1402,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"APPL2,MEFV,ZC3H12A"} {"GO.ID":"GO:0009129","Term":"pyrimidine nucleoside monophosphate metabolic process","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1403,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"DPYS,TYMP,TYMS"} {"GO.ID":"GO:0060384","Term":"innervation","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1404,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"EDN1,NRP1,VCAM1"} {"GO.ID":"GO:0060340","Term":"positive regulation of type I interferon-mediated signaling pathway","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1405,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"IRF7,NLRC5,ZBP1"} {"GO.ID":"GO:0070304","Term":"positive regulation of stress-activated protein kinase signaling cascade","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1406,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"LYN,NOD2,SCIMP"} {"GO.ID":"GO:0060445","Term":"branching involved in salivary gland morphogenesis","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1407,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"HGF,NRP1,TGM2"} {"GO.ID":"GO:0060402","Term":"calcium ion transport into cytosol","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1408,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"P2RX4,P2RX7,PML"} {"GO.ID":"GO:0045907","Term":"positive regulation of vasoconstriction","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1409,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"CD38,CYSLTR1,HRH2"} {"GO.ID":"GO:0070242","Term":"thymocyte apoptotic process","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1410,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"ADAM8,BCL2L11,JAK3"} {"GO.ID":"GO:1990858","Term":"cellular response to lectin","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1411,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"CLEC6A,KLRK1,LYN"} {"GO.ID":"GO:1990840","Term":"response to lectin","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1412,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"CLEC6A,KLRK1,LYN"} {"GO.ID":"GO:0002223","Term":"stimulatory C-type lectin receptor signaling pathway","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1413,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"CLEC6A,KLRK1,LYN"} {"GO.ID":"GO:0032682","Term":"negative regulation of chemokine production","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1414,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"KLF4,MEFV,OAS3"} {"GO.ID":"GO:0006817","Term":"phosphate ion transport","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1415,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"ANKH,SLC20A1,SLC37A1"} {"GO.ID":"GO:1903672","Term":"positive regulation of sprouting angiogenesis","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1416,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"DLL1,GHRL,KLF4"} {"GO.ID":"GO:0006582","Term":"melanin metabolic process","Annotated":19,"Significant":3,"Expected":1.15,"Rank in p.value_classic":1417,"p.value_elim":0.10288,"p.value_classic":0.10348,"genes":"CTNS,OCA2,RAPGEF2"} {"GO.ID":"GO:0045070","Term":"positive regulation of viral genome replication","Annotated":30,"Significant":4,"Expected":1.81,"Rank in p.value_classic":1418,"p.value_elim":0.10355,"p.value_classic":0.10427,"genes":"CCL5,CD28,GBP7,TOP2A"} {"GO.ID":"GO:0010464","Term":"regulation of mesenchymal cell proliferation","Annotated":30,"Significant":4,"Expected":1.81,"Rank in p.value_classic":1419,"p.value_elim":0.10355,"p.value_classic":0.10427,"genes":"CHRD,LRP5,STAT1,SYNE1"} {"GO.ID":"GO:0050854","Term":"regulation of antigen receptor-mediated signaling pathway","Annotated":54,"Significant":6,"Expected":3.26,"Rank in p.value_classic":1422,"p.value_elim":0.10467,"p.value_classic":0.10563,"genes":"BTN2A2,CEACAM1,CYLD,GBP1,LYN,STAP1"} {"GO.ID":"GO:0010977","Term":"negative regulation of neuron projection development","Annotated":133,"Significant":12,"Expected":8.03,"Rank in p.value_classic":1424,"p.value_elim":0.10494,"p.value_classic":0.10639,"genes":"B2M,CD38,DAB1,DAB2,DTNBP1,FSTL4,IL15RA,KREMEN1,LRRK2,NRP1,RTN4RL1,SEMA6B"} {"GO.ID":"GO:0097553","Term":"calcium ion transmembrane import into cytosol","Annotated":133,"Significant":12,"Expected":8.03,"Rank in p.value_classic":1425,"p.value_elim":0.10494,"p.value_classic":0.10639,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX4,P2RX7,PML,SRI,TRDN"} {"GO.ID":"GO:0050777","Term":"negative regulation of immune response","Annotated":159,"Significant":33,"Expected":9.6,"Rank in p.value_classic":115,"p.value_elim":0.10515,"p.value_classic":3e-10,"genes":"ACOD1,ASCL2,AURKB,BCL6,CD80,CEACAM1,CR1L,FGL2,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL4I1,JAK3,LYN,NLRC5,NMI,NOD2,OAS3,PARP14,PARP3,PDCD1,SERPING1,SLAMF1,SLAMF8,STAT2,TBX21,TNFRSF14,TRAFD1,TYRO3,ZC3H12A"} {"GO.ID":"GO:0098771","Term":"inorganic ion homeostasis","Annotated":393,"Significant":39,"Expected":23.74,"Rank in p.value_classic":526,"p.value_elim":0.1053,"p.value_classic":0.00153,"genes":"AGT,ANK2,ANKH,ATP13A2,ATP1B2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,EPAS1,ERC2,F2RL3,FAM20A,KCNJ10,KCNJ2,LYN,MT2A,NPR1,P2RX7,PML,SCO2,SLC11A1,SLC12A3,SLC31A2,SNX10,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0008277","Term":"regulation of G protein-coupled receptor signaling pathway","Annotated":106,"Significant":10,"Expected":6.4,"Rank in p.value_classic":1426,"p.value_elim":0.10545,"p.value_classic":0.10676,"genes":"C3,CCL5,DYNLT1,EDN1,NECAB2,PADI2,PDE4B,PLEK,RGS18,STMN1"} {"GO.ID":"GO:0006909","Term":"phagocytosis","Annotated":206,"Significant":27,"Expected":12.44,"Rank in p.value_classic":367,"p.value_elim":0.10601,"p.value_classic":0.00012,"genes":"APPL2,C2,C3,C4A,C4B,CD300LF,CD93,COLEC12,DYSF,FCN1,HAVCR1,IL15,IL15RA,LYN,MERTK,NOD2,P2RX7,PLPP4,PLSCR1,RAB20,SLAMF1,SLC11A1,STAP1,TGM2,TICAM2,TYRO3,XKR6"} {"GO.ID":"GO:0002696","Term":"positive regulation of leukocyte activation","Annotated":311,"Significant":53,"Expected":18.78,"Rank in p.value_classic":84,"p.value_elim":0.10617,"p.value_classic":4.6e-12,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CD83,CYLD,GPR183,HAVCR1,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL15RA,IL4I1,IL7,JAK2,KARS1,KITLG,KLRK1,LRRK2,LYN,NOD2,NR4A3,PDCD1LG2,RIPK2,SLAMF1,SOCS1,STAP1,TBX21,TICAM2,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:0060338","Term":"regulation of type I interferon-mediated signaling pathway","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1428,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"IRF7,NLRC5,OAS3,STAT2,ZBP1"} {"GO.ID":"GO:0090199","Term":"regulation of release of cytochrome c from mitochondria","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1429,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"BCL2L11,HGF,MMP9,PMAIP1,TNFSF10"} {"GO.ID":"GO:0071385","Term":"cellular response to glucocorticoid stimulus","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1430,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"BCL2L11,EDN1,FAM107A,JAK2,SSTR2"} {"GO.ID":"GO:0048260","Term":"positive regulation of receptor-mediated endocytosis","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1431,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"B2M,C3,DAB2,DTNBP1,SYNE1"} {"GO.ID":"GO:0046460","Term":"neutral lipid biosynthetic process","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1432,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"ACSL1,C3,DGAT2,GK,PNPLA3"} {"GO.ID":"GO:0046463","Term":"acylglycerol biosynthetic process","Annotated":42,"Significant":5,"Expected":2.54,"Rank in p.value_classic":1433,"p.value_elim":0.10625,"p.value_classic":0.10711,"genes":"ACSL1,C3,DGAT2,GK,PNPLA3"} {"GO.ID":"GO:0010817","Term":"regulation of hormone levels","Annotated":363,"Significant":28,"Expected":21.92,"Rank in p.value_classic":1438,"p.value_elim":0.10654,"p.value_classic":0.10893,"genes":"AGT,CCL5,CD38,CRHBP,CTNS,CTSL,CYP1A1,DAB2,DGAT2,DHRS3,DHRS9,EDN1,EXOC3L1,GHRL,HCAR2,HLA-DRB1,IL1RN,IL4I1,JAK2,LRP5,LYN,OSM,PLB1,SGPL1,SIDT2,SLC16A10,SRI,STX1A"} {"GO.ID":"GO:0034446","Term":"substrate adhesion-dependent cell spreading","Annotated":93,"Significant":9,"Expected":5.62,"Rank in p.value_classic":1436,"p.value_elim":0.10712,"p.value_classic":0.10837,"genes":"ANTXR1,DAB2,EPHB3,GBP1,MERTK,NRP1,PXN,S100A10,TYRO3"} {"GO.ID":"GO:0035050","Term":"embryonic heart tube development","Annotated":67,"Significant":7,"Expected":4.05,"Rank in p.value_classic":1437,"p.value_elim":0.1074,"p.value_classic":0.10848,"genes":"ASB2,DLL1,DNAAF1,EDN1,IFT122,MICAL2,SOX17"} {"GO.ID":"GO:0048661","Term":"positive regulation of smooth muscle cell proliferation","Annotated":80,"Significant":8,"Expected":4.83,"Rank in p.value_classic":1439,"p.value_elim":0.10794,"p.value_classic":0.10911,"genes":"CCL5,EDN1,HBEGF,JAK2,MMP9,NR4A3,S1PR1,STAT1"} {"GO.ID":"GO:0051960","Term":"regulation of nervous system development","Annotated":379,"Significant":29,"Expected":22.89,"Rank in p.value_classic":1444,"p.value_elim":0.10964,"p.value_classic":0.11213,"genes":"APPL2,ASCL2,B2M,BHLHE41,CX3CR1,CYSLTR1,DAB1,DLL1,DYNLT1,EGR2,EPHB3,FSTL4,GHRL,HAPLN3,LTA,LYN,NRP1,PLXNA2,RAPGEF2,S100A10,SEMA6B,TGM2,THBS2,TNFRSF21,TYMP,VCAN,VEGFC,WDR62,XRCC2"} {"GO.ID":"GO:0009743","Term":"response to carbohydrate","Annotated":176,"Significant":15,"Expected":10.63,"Rank in p.value_classic":1442,"p.value_elim":0.1103,"p.value_classic":0.11202,"genes":"CDT1,COLEC12,GHRL,GJD3,GLUL,HLA-DRB1,ICAM1,LPL,LRP5,LYN,NCF1,PNPLA3,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0002790","Term":"peptide secretion","Annotated":176,"Significant":15,"Expected":10.63,"Rank in p.value_classic":1443,"p.value_elim":0.1103,"p.value_classic":0.11202,"genes":"CCL5,CD38,CD74,CRHBP,EDN1,EXOC3L1,GHRL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,STX1A"} {"GO.ID":"GO:2001252","Term":"positive regulation of chromosome organization","Annotated":107,"Significant":10,"Expected":6.46,"Rank in p.value_classic":1441,"p.value_elim":0.11043,"p.value_classic":0.11178,"genes":"AURKB,CDK1,FEN1,GCH1,NCAPG,NCAPG2,NCAPH,PKIB,PML,TAL1"} {"GO.ID":"GO:0007059","Term":"chromosome segregation","Annotated":380,"Significant":41,"Expected":22.95,"Rank in p.value_classic":392,"p.value_elim":0.11096,"p.value_classic":0.00021,"genes":"AURKB,BIRC5,BRCA1,BUB1B,CCNE2,CDC6,CDCA5,CDK1,CDT1,CENPF,CENPK,CENPM,CENPU,CHMP4C,DMC1,EML4,ESCO2,HJURP,HORMAD1,KIF11,KIF18B,KIF23,MAD2L1,MEIKIN,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,OIP5,PLSCR1,PRC1,RMI2,SPC24,SPC25,TOP2A,UHRF1,ZWINT"} {"GO.ID":"GO:0090329","Term":"regulation of DNA-templated DNA replication","Annotated":45,"Significant":11,"Expected":2.72,"Rank in p.value_classic":342,"p.value_elim":0.11112,"p.value_classic":0.00006,"genes":"BCL6,CDT1,CHTF18,DSCC1,E2F8,MCM2,MCM4,MCM5,MCM6,MCM7,TICRR"} {"GO.ID":"GO:0061337","Term":"cardiac conduction","Annotated":77,"Significant":12,"Expected":4.65,"Rank in p.value_classic":555,"p.value_elim":0.11148,"p.value_classic":0.00211,"genes":"AGT,ANK2,ATP1B2,CAMK2D,CXADR,GJD3,KCNE5,KCNJ2,SCN4B,SPTBN4,SRI,TRDN"} {"GO.ID":"GO:0032233","Term":"positive regulation of actin filament bundle assembly","Annotated":55,"Significant":6,"Expected":3.32,"Rank in p.value_classic":1445,"p.value_elim":0.11186,"p.value_classic":0.11287,"genes":"MTSS1,NRP1,PLEK,PPM1E,PXN,S100A10"} {"GO.ID":"GO:0031100","Term":"animal organ regeneration","Annotated":55,"Significant":6,"Expected":3.32,"Rank in p.value_classic":1446,"p.value_elim":0.11186,"p.value_classic":0.11287,"genes":"CCNA2,CDK1,IGF2R,NR4A3,PTPRU,TYMS"} {"GO.ID":"GO:0070555","Term":"response to interleukin-1","Annotated":108,"Significant":19,"Expected":6.52,"Rank in p.value_classic":314,"p.value_elim":0.11235,"p.value_classic":0.00002,"genes":"ACOD1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD38,EDN1,GBP1,GBP2,GBP3,IL1RN,RIPK2,TANK,TNFRSF11A,VRK2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0032231","Term":"regulation of actin filament bundle assembly","Annotated":94,"Significant":9,"Expected":5.68,"Rank in p.value_classic":1447,"p.value_elim":0.11252,"p.value_classic":0.11382,"genes":"MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0007173","Term":"epidermal growth factor receptor signaling pathway","Annotated":94,"Significant":9,"Expected":5.68,"Rank in p.value_classic":1448,"p.value_elim":0.11252,"p.value_classic":0.11382,"genes":"AGR2,AGT,CEACAM1,GAREM1,HBEGF,MMP9,MVP,RALB,REPS2"} {"GO.ID":"GO:0070664","Term":"negative regulation of leukocyte proliferation","Annotated":74,"Significant":16,"Expected":4.47,"Rank in p.value_classic":275,"p.value_elim":0.11267,"p.value_classic":6.7e-06,"genes":"BCL6,BTN2A2,CCL8,CD274,CD80,CTLA4,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,LYN,PDCD1LG2,TNFRSF14,TNFRSF21,TSPAN32"} {"GO.ID":"GO:0002684","Term":"positive regulation of immune system process","Annotated":880,"Significant":144,"Expected":53.15,"Rank in p.value_classic":14,"p.value_elim":0.11318,"p.value_classic":8.4e-30,"genes":"ACOD1,ADAM8,AIM2,APPL2,ASCL2,AURKB,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CCL7,CCL8,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD74,CD80,CD83,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CSF1,CTLA4,CTSS,CX3CR1,CXCL10,CYLD,DDX60,EDN1,FCN1,FYB1,GBP1,GBP2,GBP5,GPR183,GPR31,GRAMD4,HAVCR1,HCAR2,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL15RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLRK1,LAG3,LILRA2,LRRK2,LTA,LYN,LYVE1,MEFV,NLRC5,NMI,NOD2,NR4A3,OAS3,P2RX4,P2RX7,PARP9,PDCD1LG2,PDE4B,PLPP4,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLC11A1,SOCS1,STAP1,TAP2,TBX21,TESC,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TRIM31,TYRO3,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0042088","Term":"T-helper 1 type immune response","Annotated":45,"Significant":12,"Expected":2.72,"Rank in p.value_classic":285,"p.value_elim":0.11341,"p.value_classic":9.8e-06,"genes":"ASCL2,CD80,HLA-DRB1,IL12RB1,IL18BP,IL27,JAK3,RELB,RIPK2,SLAMF1,SLC11A1,TBX21"} {"GO.ID":"GO:0006953","Term":"acute-phase response","Annotated":31,"Significant":4,"Expected":1.87,"Rank in p.value_classic":1449,"p.value_elim":0.11353,"p.value_classic":0.11432,"genes":"APOL2,CD163,PLSCR1,TNFRSF11A"} {"GO.ID":"GO:0070570","Term":"regulation of neuron projection regeneration","Annotated":31,"Significant":4,"Expected":1.87,"Rank in p.value_classic":1450,"p.value_elim":0.11353,"p.value_classic":0.11432,"genes":"KLF4,KREMEN1,RTN4RL1,SCARF1"} {"GO.ID":"GO:0048145","Term":"regulation of fibroblast proliferation","Annotated":81,"Significant":8,"Expected":4.89,"Rank in p.value_classic":1453,"p.value_elim":0.11384,"p.value_classic":0.11505,"genes":"AGT,CCNA2,CD74,CDC6,E2F1,LTA,PARP10,PML"} {"GO.ID":"GO:0019217","Term":"regulation of fatty acid metabolic process","Annotated":68,"Significant":7,"Expected":4.11,"Rank in p.value_classic":1451,"p.value_elim":0.11389,"p.value_classic":0.11501,"genes":"APPL2,BRCA1,CD74,CEACAM1,NR4A3,PDK4,SLC45A3"} {"GO.ID":"GO:0032414","Term":"positive regulation of ion transmembrane transporter activity","Annotated":68,"Significant":7,"Expected":4.11,"Rank in p.value_classic":1452,"p.value_elim":0.11389,"p.value_classic":0.11501,"genes":"ABCB1,ANK2,ATP1B2,CTSS,EDN1,TESC,TRDN"} {"GO.ID":"GO:0042098","Term":"T cell proliferation","Annotated":179,"Significant":36,"Expected":10.81,"Rank in p.value_classic":107,"p.value_elim":0.11422,"p.value_classic":1.2e-10,"genes":"BCL6,BTN2A2,BTN3A1,CCL5,CD274,CD28,CD80,CTLA4,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12RB1,IL15,IL27,IL4I1,IRF1,JAK2,KITLG,P2RX7,PDCD1LG2,PSMB10,RIPK2,SLAMF1,SLC11A1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0046636","Term":"negative regulation of alpha-beta T cell activation","Annotated":35,"Significant":8,"Expected":2.11,"Rank in p.value_classic":488,"p.value_elim":0.11453,"p.value_classic":0.00093,"genes":"ASCL2,BCL6,CD274,JAK3,SOCS1,TBX21,TNFRSF14,ZC3H12A"} {"GO.ID":"GO:2000404","Term":"regulation of T cell migration","Annotated":43,"Significant":5,"Expected":2.6,"Rank in p.value_classic":1454,"p.value_elim":0.11462,"p.value_classic":0.11554,"genes":"ADAM8,ASCL2,CCL5,CXCL10,TNFRSF14"} {"GO.ID":"GO:0033628","Term":"regulation of cell adhesion mediated by integrin","Annotated":43,"Significant":5,"Expected":2.6,"Rank in p.value_classic":1455,"p.value_elim":0.11462,"p.value_classic":0.11554,"genes":"CCL5,LYN,MUC1,PDE3B,TESC"} {"GO.ID":"GO:0071867","Term":"response to monoamine","Annotated":43,"Significant":5,"Expected":2.6,"Rank in p.value_classic":1456,"p.value_elim":0.11462,"p.value_classic":0.11554,"genes":"DTNBP1,GNG2,LRRK2,NR4A3,TGM2"} {"GO.ID":"GO:0071869","Term":"response to catecholamine","Annotated":43,"Significant":5,"Expected":2.6,"Rank in p.value_classic":1457,"p.value_elim":0.11462,"p.value_classic":0.11554,"genes":"DTNBP1,GNG2,LRRK2,NR4A3,TGM2"} {"GO.ID":"GO:0070229","Term":"negative regulation of lymphocyte apoptotic process","Annotated":34,"Significant":7,"Expected":2.05,"Rank in p.value_classic":622,"p.value_elim":0.11484,"p.value_classic":0.00366,"genes":"AURKB,BCL6,CCL5,CD74,IDO1,JAK3,PDCD1"} {"GO.ID":"GO:0009306","Term":"protein secretion","Annotated":278,"Significant":22,"Expected":16.79,"Rank in p.value_classic":1473,"p.value_elim":0.11544,"p.value_classic":0.11766,"genes":"ADAM8,ATP13A2,C1QTNF5,CCL5,CD38,COMP,GHRL,GSDMD,HCAR2,HLA-DRB1,IL12A,IL1RN,JAK2,LRP5,P2RX7,PLEK,RSAD2,SIDT2,SRI,STX1A,SUCNR1,VEGFC"} {"GO.ID":"GO:0035592","Term":"establishment of protein localization to extracellular region","Annotated":278,"Significant":22,"Expected":16.79,"Rank in p.value_classic":1474,"p.value_elim":0.11544,"p.value_classic":0.11766,"genes":"ADAM8,ATP13A2,C1QTNF5,CCL5,CD38,COMP,GHRL,GSDMD,HCAR2,HLA-DRB1,IL12A,IL1RN,JAK2,LRP5,P2RX7,PLEK,RSAD2,SIDT2,SRI,STX1A,SUCNR1,VEGFC"} {"GO.ID":"GO:0045987","Term":"positive regulation of smooth muscle contraction","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1458,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"EDN1,GHRL,PROK2"} {"GO.ID":"GO:1900407","Term":"regulation of cellular response to oxidative stress","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1459,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"AIFM2,DHFR,GCH1"} {"GO.ID":"GO:0050860","Term":"negative regulation of T cell receptor signaling pathway","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1460,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"BTN2A2,CEACAM1,GBP1"} {"GO.ID":"GO:0099623","Term":"regulation of cardiac muscle cell membrane repolarization","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1461,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"ANK2,KCNE5,SCN4B"} {"GO.ID":"GO:0097066","Term":"response to thyroid hormone","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1462,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"C2,CTSL,CTSS"} {"GO.ID":"GO:0060586","Term":"multicellular organismal-level iron ion homeostasis","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1463,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"B2M,EPAS1,SLC11A1"} {"GO.ID":"GO:0002438","Term":"acute inflammatory response to antigenic stimulus","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1464,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"C3,HLA-E,IL31RA"} {"GO.ID":"GO:0044550","Term":"secondary metabolite biosynthetic process","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1465,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"CTNS,OCA2,RAPGEF2"} {"GO.ID":"GO:0008156","Term":"negative regulation of DNA replication","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1466,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"BCL6,CDC6,CDT1"} {"GO.ID":"GO:0035162","Term":"embryonic hemopoiesis","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1467,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"FLT3LG,KITLG,TAL1"} {"GO.ID":"GO:0046794","Term":"transport of virus","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1468,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"CTSL,DYNLT1,TPCN1"} {"GO.ID":"GO:0006244","Term":"pyrimidine nucleotide catabolic process","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1469,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"DPYS,TYMP,UNG"} {"GO.ID":"GO:0035774","Term":"positive regulation of insulin secretion involved in cellular response to glucose stimulus","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1470,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"GHRL,HLA-DRB1,SRI"} {"GO.ID":"GO:0046629","Term":"gamma-delta T cell activation","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1471,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"CXADR,ITK,NOD2"} {"GO.ID":"GO:0014059","Term":"regulation of dopamine secretion","Annotated":20,"Significant":3,"Expected":1.21,"Rank in p.value_classic":1472,"p.value_elim":0.11588,"p.value_classic":0.11654,"genes":"DTNBP1,SYT1,SYT6"} {"GO.ID":"GO:0061081","Term":"positive regulation of myeloid leukocyte cytokine production involved in immune response","Annotated":34,"Significant":8,"Expected":2.05,"Rank in p.value_classic":477,"p.value_elim":0.11718,"p.value_classic":0.00076,"genes":"CD74,HLA-G,NOD2,NR4A3,P2RX7,RIPK2,TICAM2,TLR7"} {"GO.ID":"GO:0016485","Term":"protein processing","Annotated":192,"Significant":16,"Expected":11.6,"Rank in p.value_classic":1504,"p.value_elim":0.11741,"p.value_classic":0.11928,"genes":"ADAM8,C1R,C1RL,CARD16,CASP4,CASP7,CHAC1,COMP,CTSL,CTSS,ECEL1,LRRK2,P2RX7,RIPK2,S100A10,THBD"} {"GO.ID":"GO:0002520","Term":"immune system development","Annotated":176,"Significant":21,"Expected":10.63,"Rank in p.value_classic":557,"p.value_elim":0.11776,"p.value_classic":0.00216,"genes":"ACOD1,BCL2L11,BCL6,CD274,CD28,EPHB3,EXO1,HLA-B,HLA-E,HLA-G,IDO1,IL15,LRP5,LTA,LYN,PARP3,PDCD1,POLB,TBX21,TNFRSF11A,UNG"} {"GO.ID":"GO:0031345","Term":"negative regulation of cell projection organization","Annotated":178,"Significant":15,"Expected":10.75,"Rank in p.value_classic":1505,"p.value_elim":0.1182,"p.value_classic":0.12001,"genes":"B2M,CD38,DAB1,DAB2,DTNBP1,FSTL4,IL15RA,KREMEN1,LIMK2,LRRK2,NRP1,RAPGEF2,RTN4RL1,SEMA6B,STAP1"} {"GO.ID":"GO:2001214","Term":"positive regulation of vasculogenesis","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1476,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CEACAM1,RAPGEF2"} {"GO.ID":"GO:0034080","Term":"CENP-A containing chromatin assembly","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1477,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"HJURP,OIP5"} {"GO.ID":"GO:0001915","Term":"negative regulation of T cell mediated cytotoxicity","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1478,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CEACAM1,HLA-G"} {"GO.ID":"GO:0060315","Term":"negative regulation of ryanodine-sensitive calcium-release channel activity","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1479,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"SRI,TRDN"} {"GO.ID":"GO:0070189","Term":"kynurenine metabolic process","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1480,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"IDO1,IDO2"} {"GO.ID":"GO:0031055","Term":"chromatin remodeling at centromere","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1481,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"HJURP,OIP5"} {"GO.ID":"GO:0045916","Term":"negative regulation of complement activation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1482,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CR1L,SERPING1"} {"GO.ID":"GO:0099509","Term":"regulation of presynaptic cytosolic calcium ion concentration","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1483,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"ERC2,SV2B"} {"GO.ID":"GO:0034115","Term":"negative regulation of heterotypic cell-cell adhesion","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1484,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"IL1RN,KLF4"} {"GO.ID":"GO:0060837","Term":"blood vessel endothelial cell differentiation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1485,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"DLL1,NRP1"} {"GO.ID":"GO:1900226","Term":"negative regulation of NLRP3 inflammasome complex assembly","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1486,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"MEFV,TRIM31"} {"GO.ID":"GO:1902043","Term":"positive regulation of extrinsic apoptotic signaling pathway via death domain receptors","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1487,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"ATF3,PMAIP1"} {"GO.ID":"GO:0070587","Term":"regulation of cell-cell adhesion involved in gastrulation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1488,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"IL1RN,KLF4"} {"GO.ID":"GO:0050665","Term":"hydrogen peroxide biosynthetic process","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1489,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CTNS,CYP1A1"} {"GO.ID":"GO:0042118","Term":"endothelial cell activation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1490,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CXCL10,P2RX4"} {"GO.ID":"GO:0044828","Term":"negative regulation by host of viral genome replication","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1491,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"CCL8,ZC3H12A"} {"GO.ID":"GO:0044837","Term":"actomyosin contractile ring organization","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1492,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"ANLN,IQGAP3"} {"GO.ID":"GO:0072148","Term":"epithelial cell fate commitment","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1493,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"DLL1,NRP1"} {"GO.ID":"GO:0032823","Term":"regulation of natural killer cell differentiation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1494,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"IL15,IL15RA"} {"GO.ID":"GO:0051133","Term":"regulation of NK T cell activation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1495,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"IL12A,JAK2"} {"GO.ID":"GO:0048243","Term":"norepinephrine secretion","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1496,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"ADORA3,STX1A"} {"GO.ID":"GO:1901388","Term":"regulation of transforming growth factor beta activation","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1497,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0002883","Term":"regulation of hypersensitivity","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1498,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"C3,HLA-E"} {"GO.ID":"GO:2000833","Term":"positive regulation of steroid hormone secretion","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1499,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"DAB2,GHRL"} {"GO.ID":"GO:0021561","Term":"facial nerve development","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1500,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"EGR2,NRP1"} {"GO.ID":"GO:0021610","Term":"facial nerve morphogenesis","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1501,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"EGR2,NRP1"} {"GO.ID":"GO:0090085","Term":"regulation of protein deubiquitination","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1502,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"TANK,ZC3H12A"} {"GO.ID":"GO:0060068","Term":"vagina development","Annotated":10,"Significant":2,"Expected":0.6,"Rank in p.value_classic":1503,"p.value_elim":0.11833,"p.value_classic":0.11883,"genes":"MERTK,TYRO3"} {"GO.ID":"GO:0030225","Term":"macrophage differentiation","Annotated":56,"Significant":6,"Expected":3.38,"Rank in p.value_classic":1506,"p.value_elim":0.1193,"p.value_classic":0.12035,"genes":"CSF1,HLA-DRB1,IL15,IL31RA,MMP9,SOCS1"} {"GO.ID":"GO:0042058","Term":"regulation of epidermal growth factor receptor signaling pathway","Annotated":56,"Significant":6,"Expected":3.38,"Rank in p.value_classic":1507,"p.value_elim":0.1193,"p.value_classic":0.12035,"genes":"AGR2,AGT,CEACAM1,MMP9,MVP,RALB"} {"GO.ID":"GO:0046470","Term":"phosphatidylcholine metabolic process","Annotated":56,"Significant":6,"Expected":3.38,"Rank in p.value_classic":1508,"p.value_elim":0.1193,"p.value_classic":0.12035,"genes":"CDS1,ENPP2,PCYT1A,PLAAT3,PLAAT4,PLB1"} {"GO.ID":"GO:0045471","Term":"response to ethanol","Annotated":82,"Significant":8,"Expected":4.95,"Rank in p.value_classic":1510,"p.value_elim":0.1199,"p.value_classic":0.12117,"genes":"CCL7,CDK1,CRHBP,GRIN3A,POLB,TNFRSF11A,TYMS,VCAM1"} {"GO.ID":"GO:0007154","Term":"cell communication","Annotated":4774,"Significant":385,"Expected":288.33,"Rank in p.value_classic":72,"p.value_elim":0.12008,"p.value_classic":2.8e-13,"genes":"ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,ANK2,APOL3,APPL2,ARAP2,ASB2,ASIC1,ATF3,ATP1B2,AURKB,BANK1,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C3,CADPS2,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC45,CDC6,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CHAC1,CHMP4C,CHRD,CIBAR1,CISH,CLEC6A,CLSPN,COLEC12,COLQ,COMP,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DNM1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,ECEL1,EDA,EDN1,EGR2,EME1,EPAS1,EPHB3,ERC2,EXOC3L1,F2RL3,FAM107A,FAM13A,FAS,FBXO6,FCN1,FGD5,FLT3LG,FSTL4,FYB1,G0S2,GABRA3,GADD45B,GAL3ST4,GAREM1,GBP1,GBP2,GBP5,GBP7,GFRA2,GHRL,GJD3,GLDN,GLIPR2,GLUL,GNG2,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GSDMD,GTPBP1,GTSE1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,HORMAD1,HRH2,HSH2D,HTRA1,ICAM1,IFI27,IFI35,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAD2L1,MAML3,MAP1LC3C,MCF2L,MCOLN2,MCTP2,MEFV,MERTK,MIR503,MMP9,MRAS,MTSS1,MUC1,MVP,MYOF,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRP1,NUCB1,NUF2,NXPH2,NYAP2,OAS2,OAS3,OIP5,OLFML2B,ONECUT2,OPTN,OR2I1P,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PROK2,PRRT2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RIPK2,RNF213,RSAD2,RSU1,RXFP1,S100A13,S1PR1,SCIMP,SCN4B,SECTM1,SEMA6B,SEPTIN4,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLC12A3,SLC16A10,SLC20A1,SOCS1,SOX17,SPC24,SPC25,SPTBN4,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYT1,SYT6,TAGAP,TANK,TGM2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TPCN1,TRABD2A,TRDN,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYRO3,UBD,VCAM1,VEGFC,VRK2,WDR76,WWP1,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0070661","Term":"leukocyte proliferation","Annotated":279,"Significant":47,"Expected":16.85,"Rank in p.value_classic":106,"p.value_elim":0.12019,"p.value_classic":1.2e-10,"genes":"BCL6,BTN2A2,BTN3A1,CCL5,CCL8,CD274,CD28,CD38,CD40,CD74,CD80,CSF1,CSF2RB,CTLA4,GPR183,HELLS,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,P2RX7,PDCD1LG2,PSMB10,RIPK2,SLAMF1,SLC11A1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0001508","Term":"action potential","Annotated":109,"Significant":10,"Expected":6.58,"Rank in p.value_classic":1512,"p.value_elim":0.12077,"p.value_classic":0.12223,"genes":"ANK2,CAMK2D,CXADR,KCNE5,KCNJ2,NRCAM,P2RX4,SCN4B,SRI,USP53"} {"GO.ID":"GO:0035725","Term":"sodium ion transmembrane transport","Annotated":109,"Significant":10,"Expected":6.58,"Rank in p.value_classic":1513,"p.value_elim":0.12077,"p.value_classic":0.12223,"genes":"ASIC1,ATP1B2,CAMK2D,SCN4B,SLC12A3,SLC20A1,SLC4A7,SLC6A12,TESC,TPCN1"} {"GO.ID":"GO:0099643","Term":"signal release from synapse","Annotated":114,"Significant":14,"Expected":6.89,"Rank in p.value_classic":729,"p.value_elim":0.12106,"p.value_classic":0.00868,"genes":"ASIC1,CADPS2,DTNBP1,DYSF,ERC2,LRRK2,MCTP2,MYOF,P2RX7,PRRT2,STX11,STX1A,SV2B,SYT1"} {"GO.ID":"GO:0007269","Term":"neurotransmitter secretion","Annotated":114,"Significant":14,"Expected":6.89,"Rank in p.value_classic":730,"p.value_elim":0.12106,"p.value_classic":0.00868,"genes":"ASIC1,CADPS2,DTNBP1,DYSF,ERC2,LRRK2,MCTP2,MYOF,P2RX7,PRRT2,STX11,STX1A,SV2B,SYT1"} {"GO.ID":"GO:0034612","Term":"response to tumor necrosis factor","Annotated":222,"Significant":35,"Expected":13.41,"Rank in p.value_classic":191,"p.value_elim":0.12223,"p.value_classic":1.6e-07,"genes":"ACOD1,AIM2,BRCA1,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CRHBP,CX3CR1,CYLD,EDN1,FAS,GBP1,GBP2,GBP3,GCH1,IL18BP,JAK2,NUB1,PID1,STAT1,TANK,TIFA,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,UBD,VCAM1,ZC3H12A"} {"GO.ID":"GO:0046883","Term":"regulation of hormone secretion","Annotated":179,"Significant":15,"Expected":10.81,"Rank in p.value_classic":1515,"p.value_elim":0.12227,"p.value_classic":0.12413,"genes":"AGT,CCL5,CD38,CRHBP,DAB2,EDN1,GHRL,HCAR2,HLA-DRB1,JAK2,LRP5,OSM,SIDT2,SRI,STX1A"} {"GO.ID":"GO:0019882","Term":"antigen processing and presentation","Annotated":103,"Significant":36,"Expected":6.22,"Rank in p.value_classic":24,"p.value_elim":0.12236,"p.value_classic":9.2e-19,"genes":"B2M,CD1A,CD1C,CD74,CTSL,CTSS,ERAP2,FGL2,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,NOD2,PSMB8,PSME1,RELB,SLC11A1,TAP1,TAP2,TAPBP,TAPBPL"} {"GO.ID":"GO:0002449","Term":"lymphocyte mediated immunity","Annotated":231,"Significant":51,"Expected":13.95,"Rank in p.value_classic":41,"p.value_elim":0.12242,"p.value_classic":2.6e-16,"genes":"B2M,BCL6,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD1A,CD1C,CD28,CD40,CD74,CD80,CEACAM1,CR1L,CSF2RB,EXO1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL4I1,IRF7,KLRK1,LAG3,LTA,NOD2,P2RX7,PARP3,RNF19B,RSAD2,SERPING1,SLAMF1,SLAMF6,SLAMF7,TAP2,TBX21,TLR8,UNG"} {"GO.ID":"GO:0051047","Term":"positive regulation of secretion","Annotated":234,"Significant":22,"Expected":14.13,"Rank in p.value_classic":951,"p.value_elim":0.12265,"p.value_classic":0.0261,"genes":"ADAM8,ATP13A2,CADPS2,CD38,DAB2,DTNBP1,EDN1,GHRL,HCAR2,HLA-DRB1,HLA-F,JAK2,NPR1,P2RX4,P2RX7,S100A10,SCIN,SRI,STX1A,SYT1,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0019229","Term":"regulation of vasoconstriction","Annotated":44,"Significant":5,"Expected":2.66,"Rank in p.value_classic":1516,"p.value_elim":0.1233,"p.value_classic":0.12427,"genes":"AGT,CD38,CYSLTR1,EDN1,HRH2"} {"GO.ID":"GO:0009410","Term":"response to xenobiotic stimulus","Annotated":310,"Significant":24,"Expected":18.72,"Rank in p.value_classic":1526,"p.value_elim":0.12374,"p.value_classic":0.12619,"genes":"ABCB1,ACSL1,AIM2,CBR3,CD38,CD69,CDK1,CENPF,CRHBP,CYP1A1,E2F1,EDN1,EPHX1,LTA,LYN,MCM7,P2RX7,PDE4B,PPM1E,RAD54B,RAD54L,STAT1,TYMS,VEGFC"} {"GO.ID":"GO:0030195","Term":"negative regulation of blood coagulation","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1517,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"CEACAM1,EDN1,SERPING1,THBD"} {"GO.ID":"GO:0034405","Term":"response to fluid shear stress","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1518,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"KLF4,MTSS1,P2RX4,P2RX7"} {"GO.ID":"GO:0141085","Term":"regulation of inflammasome-mediated signaling pathway","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1519,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"GBP2,GBP5,MEFV,TRIM31"} {"GO.ID":"GO:0016339","Term":"calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1520,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"CDH5,PCDH12,PCDHGC3,SELL"} {"GO.ID":"GO:0001782","Term":"B cell homeostasis","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1521,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"BCL2L11,CD74,LYN,TNFSF13B"} {"GO.ID":"GO:0046189","Term":"phenol-containing compound biosynthetic process","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1522,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"CTNS,GCH1,OCA2,RAPGEF2"} {"GO.ID":"GO:0001504","Term":"neurotransmitter uptake","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1523,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"KCNJ10,SLC18A1,SLC6A12,SYNGR3"} {"GO.ID":"GO:0045730","Term":"respiratory burst","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1524,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"NCF1,NCF1C,SLAMF8,SLC11A1"} {"GO.ID":"GO:0015872","Term":"dopamine transport","Annotated":32,"Significant":4,"Expected":1.93,"Rank in p.value_classic":1525,"p.value_elim":0.12392,"p.value_classic":0.12476,"genes":"DTNBP1,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0002253","Term":"activation of immune response","Annotated":444,"Significant":76,"Expected":26.82,"Rank in p.value_classic":35,"p.value_elim":0.12494,"p.value_classic":6.1e-17,"genes":"ACOD1,AIM2,APPL2,AURKB,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CD274,CD28,CD300LF,CD38,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CTLA4,CTSS,CYLD,DDX60,FCN1,FYB1,GBP1,GBP2,GBP5,GRAMD4,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,IFI35,IFIH1,IRF1,IRF4,IRF7,ITK,KLRK1,LILRA2,LYN,MEFV,NMI,NOD2,NR4A3,OAS3,PDE4B,PLPP4,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,STAP1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF21,TRIM31,TYRO3,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0045321","Term":"leukocyte activation","Annotated":793,"Significant":113,"Expected":47.89,"Rank in p.value_classic":26,"p.value_elim":0.12606,"p.value_classic":2.2e-18,"genes":"ADAM8,ASCL2,B2M,BANK1,BATF2,BATF3,BCL6,BTN2A2,BTN3A1,CCL5,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CD93,CEACAM1,CSF1,CTLA4,CTSL,CX3CR1,CXADR,CYLD,DLL1,DYSF,EDN1,EXO1,FGL1,FGL2,GPR183,HAVCR1,HELLS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LRRK2,LYN,MERTK,NMI,NOD2,NR4A3,P2RX7,PARP3,PDCD1LG2,PLSCR1,PSMB10,PTGER4,RELB,RIPK2,RSAD2,S100A13,SBNO2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,STAP1,SUCNR1,TBX21,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,UBD,UNG,VCAM1,ZC3H12A"} {"GO.ID":"GO:1990748","Term":"cellular detoxification","Annotated":83,"Significant":8,"Expected":5.01,"Rank in p.value_classic":1529,"p.value_elim":0.12614,"p.value_classic":0.12746,"genes":"ABCG2,AIFM2,DHFR,GCH1,GSTK1,LTC4S,PIM1,SLC11A1"} {"GO.ID":"GO:0048513","Term":"animal organ development","Annotated":2269,"Significant":149,"Expected":137.04,"Rank in p.value_classic":1551,"p.value_elim":0.12647,"p.value_classic":0.13371,"genes":"AATK,ADAM8,AGR2,AGT,AIM2,AMER1,ANK2,ANKH,ASB2,ASCL2,ATF3,ATF5,ATP1B2,ATP8B1,B2M,BCL2L11,C1QTNF5,C21orf91,CASP7,CCNA2,CCNF,CDK1,CEACAM1,CELSR1,CENPF,COMP,CSF1,CTNS,CX3CR1,CXADR,CXCL10,CYP1A1,DAB1,DAB2,DGAT2,DHRS3,DLL1,DMC1,DNAAF1,DTNBP1,E2F1,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,ETV7,FAM20A,FGL1,FLT3LG,GCNT3,GHRL,GLIPR2,HBEGF,HELLS,HESX1,HGF,HSD11B1,HTRA1,IFT122,IGF2R,IL15,IL7,INA,IQGAP3,ITGA7,ITGB1BP2,JAK2,KIF26A,KITLG,KLF4,LBH,LIMK2,LPL,LRP5,LRRK2,LTA,MAF,MAFF,MCM2,MDGA1,MERTK,MICAL2,MMP9,MTSS1,MYO7B,MYOZ2,NR4A3,NRCAM,NRP1,OAS2,OLIG1,ONECUT2,OVOL1,P2RX7,PADI2,PCDH12,PIM1,PKD1L3,PLAAT3,PLAAT4,PLCD3,PLXNA2,PML,POLB,PRKX,PTGER4,PTPRU,RAPGEF2,RHOBTB3,RTN4RL1,RXFP1,S1PR1,SBNO2,SCIN,SCO2,SELENOP,SEMA6B,SGPL1,SIDT2,SLC20A1,SLC4A7,SNX10,SOBP,SOX17,SRI,SSBP3,SSTR2,STAT1,STMN1,SYNE1,SYNGR3,TACC2,TAL1,TGM2,TIFAB,TMEM119,TMEM176B,TNFAIP6,TNFRSF11A,TNFSF10,TYMS,TYRO3,VAMP5,VCAM1,VEGFC,WDR62,XYLT1"} {"GO.ID":"GO:0030097","Term":"hemopoiesis","Annotated":806,"Significant":88,"Expected":48.68,"Rank in p.value_classic":162,"p.value_elim":0.12694,"p.value_classic":3e-08,"genes":"ADAM8,ALAS1,ANLN,ASCL2,B2M,BATF2,BATF3,BCL6,BTN2A2,CD101,CD28,CD74,CD80,CD83,CEACAM1,CSF1,CTLA4,CTSL,CYLD,DLL1,EPAS1,ESCO2,FAXDC2,FGL2,FLT3LG,GPR183,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KITLG,KLF4,LAG3,LILRB3,LYN,MAF,MERTK,MMP9,NCAPG2,OSM,PIM1,PLEK,PML,PRKX,PTGER4,RELB,RIPK2,RSAD2,SBNO2,SCIN,SGPL1,SH3PXD2A,SLAMF1,SLAMF6,SLAMF8,SNX10,SOCS1,SSBP3,STAT1,TAL1,TBX21,TESC,TIFAB,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFSF13B,TNFSF8,TOP2A,TYRO3,UBD,VCAM1,ZC3H12A"} {"GO.ID":"GO:0051952","Term":"regulation of amine transport","Annotated":57,"Significant":6,"Expected":3.44,"Rank in p.value_classic":1530,"p.value_elim":0.12697,"p.value_classic":0.12808,"genes":"ADORA3,DTNBP1,P2RX7,STX1A,SYT1,SYT6"} {"GO.ID":"GO:0099024","Term":"plasma membrane invagination","Annotated":57,"Significant":6,"Expected":3.44,"Rank in p.value_classic":1531,"p.value_elim":0.12697,"p.value_classic":0.12808,"genes":"APPL2,AURKB,C3,HAVCR1,STAP1,XKR6"} {"GO.ID":"GO:0000079","Term":"regulation of cyclin-dependent protein serine/threonine kinase activity","Annotated":70,"Significant":7,"Expected":4.23,"Rank in p.value_classic":1533,"p.value_elim":0.12745,"p.value_classic":0.12868,"genes":"CCNA2,CCNE2,CCNF,CDC25A,CDC6,CDKN2C,PKMYT1"} {"GO.ID":"GO:0044057","Term":"regulation of system process","Annotated":388,"Significant":37,"Expected":23.43,"Rank in p.value_classic":631,"p.value_elim":0.1283,"p.value_classic":0.00391,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CRHBP,CXADR,CYSLTR1,DAB2,DLGAP3,EDN1,EGR2,EPAS1,GCH1,GHRL,GJD3,HBEGF,HRH2,KCNE5,KCNJ2,LRRK2,NPR1,NR4A3,P2RX4,PDE4B,PROK2,SCN4B,SPTBN4,SRI,STX1A,SYNE1,TIFAB,TNFRSF21,TRDN,TYMP,ZC3H12A"} {"GO.ID":"GO:0090330","Term":"regulation of platelet aggregation","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1534,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"CEACAM1,JAK2,LYN"} {"GO.ID":"GO:1903902","Term":"positive regulation of viral life cycle","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1535,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"CD74,HLA-DRB1,TYRO3"} {"GO.ID":"GO:0010743","Term":"regulation of macrophage derived foam cell differentiation","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1536,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"AGT,CSF1,LPL"} {"GO.ID":"GO:0044342","Term":"type B pancreatic cell proliferation","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1537,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"NR4A3,RASGRF1,SIDT2"} {"GO.ID":"GO:0010878","Term":"cholesterol storage","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1538,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"LPL,SOAT1,TTC39B"} {"GO.ID":"GO:0010669","Term":"epithelial structure maintenance","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1539,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"CXADR,NOD2,PIWIL4"} {"GO.ID":"GO:0099625","Term":"ventricular cardiac muscle cell membrane repolarization","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1540,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"ANK2,KCNE5,SCN4B"} {"GO.ID":"GO:0046039","Term":"GTP metabolic process","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1541,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"GIMAP7,GTPBP1,LRRK2"} {"GO.ID":"GO:0014856","Term":"skeletal muscle cell proliferation","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1542,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"HGF,JAK2,NDC80"} {"GO.ID":"GO:0014829","Term":"vascular associated smooth muscle contraction","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1543,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"CD38,COMP,EDN1"} {"GO.ID":"GO:0086010","Term":"membrane depolarization during action potential","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1544,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"ANK2,KCNJ2,SCN4B"} {"GO.ID":"GO:0040018","Term":"positive regulation of multicellular organism growth","Annotated":21,"Significant":3,"Expected":1.27,"Rank in p.value_classic":1545,"p.value_elim":0.12945,"p.value_classic":0.13017,"genes":"CSF1,GHRL,SPTBN4"} {"GO.ID":"GO:0006639","Term":"acylglycerol metabolic process","Annotated":97,"Significant":9,"Expected":5.86,"Rank in p.value_classic":1546,"p.value_elim":0.12961,"p.value_classic":0.13106,"genes":"ACSL1,C3,DGAT2,G6PC1,GK,LPL,PLAAT3,PLB1,PNPLA3"} {"GO.ID":"GO:0008037","Term":"cell recognition","Annotated":97,"Significant":9,"Expected":5.86,"Rank in p.value_classic":1547,"p.value_elim":0.12961,"p.value_classic":0.13106,"genes":"C4B,COLEC12,EPHB3,FCN1,NRCAM,NRP1,PCDH12,TNFRSF21,VCAN"} {"GO.ID":"GO:0008630","Term":"intrinsic apoptotic signaling pathway in response to DNA damage","Annotated":97,"Significant":9,"Expected":5.86,"Rank in p.value_classic":1548,"p.value_elim":0.12961,"p.value_classic":0.13106,"genes":"BCL2A1,BCL2L11,BRCA1,CD74,E2F1,MUC1,PML,POLB,TMEM109"} {"GO.ID":"GO:0002695","Term":"negative regulation of leukocyte activation","Annotated":150,"Significant":31,"Expected":9.06,"Rank in p.value_classic":128,"p.value_elim":0.13096,"p.value_classic":1.2e-09,"genes":"ASCL2,BANK1,BCL6,BTN2A2,CD274,CD300LF,CD74,CD80,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL31RA,IL4I1,IRF1,JAK3,LAG3,LYN,MERTK,PARP3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,TYRO3,ZC3H12A"} {"GO.ID":"GO:0071692","Term":"protein localization to extracellular region","Annotated":283,"Significant":22,"Expected":17.09,"Rank in p.value_classic":1554,"p.value_elim":0.13182,"p.value_classic":0.13426,"genes":"ADAM8,ATP13A2,C1QTNF5,CCL5,CD38,COMP,GHRL,GSDMD,HCAR2,HLA-DRB1,IL12A,IL1RN,JAK2,LRP5,P2RX7,PLEK,RSAD2,SIDT2,SRI,STX1A,SUCNR1,VEGFC"} {"GO.ID":"GO:0010611","Term":"regulation of cardiac muscle hypertrophy","Annotated":45,"Significant":5,"Expected":2.72,"Rank in p.value_classic":1549,"p.value_elim":0.13226,"p.value_classic":0.13329,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0032413","Term":"negative regulation of ion transmembrane transporter activity","Annotated":45,"Significant":5,"Expected":2.72,"Rank in p.value_classic":1550,"p.value_elim":0.13226,"p.value_classic":0.13329,"genes":"CAMK2D,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0098660","Term":"inorganic ion transmembrane transport","Annotated":615,"Significant":44,"Expected":37.14,"Rank in p.value_classic":1559,"p.value_elim":0.13238,"p.value_classic":0.136,"genes":"ANK2,ANKH,ANO4,APOL1,ASIC1,ATP1B2,ATP6V0D2,CACNA2D3,CAMK2D,CLIC5,CTNS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,GABRA3,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MCOLN2,OCA2,P2RX4,P2RX7,PDE4B,PKD1L3,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC37A1,SLC4A7,SLC6A12,SRI,TESC,TPCN1,TRDN"} {"GO.ID":"GO:0000281","Term":"mitotic cytokinesis","Annotated":84,"Significant":8,"Expected":5.07,"Rank in p.value_classic":1552,"p.value_elim":0.13254,"p.value_classic":0.13391,"genes":"ANLN,AURKB,BIRC5,CHMP4C,IQGAP3,KIF23,NUSAP1,STMN1"} {"GO.ID":"GO:1901992","Term":"positive regulation of mitotic cell cycle phase transition","Annotated":84,"Significant":8,"Expected":5.07,"Rank in p.value_classic":1553,"p.value_elim":0.13254,"p.value_classic":0.13391,"genes":"CCNE2,CDC25A,CDC6,CDCA5,CDK1,CYP1A1,DTL,RRM2"} {"GO.ID":"GO:0006575","Term":"cellular modified amino acid metabolic process","Annotated":139,"Significant":12,"Expected":8.39,"Rank in p.value_classic":1555,"p.value_elim":0.13284,"p.value_classic":0.13458,"genes":"CHAC1,CTNS,DHFR,GCH1,GGT5,GSTK1,MTHFD2,PLA1A,PLSCR1,SERINC5,SLC16A10,TYMS"} {"GO.ID":"GO:0023052","Term":"signaling","Annotated":4712,"Significant":377,"Expected":284.58,"Rank in p.value_classic":78,"p.value_elim":0.13327,"p.value_classic":2.4e-12,"genes":"ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,ANK2,APOL3,APPL2,ARAP2,ASB2,ASIC1,ATF3,AURKB,BANK1,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C3,CADPS2,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC45,CDC6,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CHAC1,CHMP4C,CHRD,CIBAR1,CISH,CLEC6A,CLSPN,COLEC12,COLQ,COMP,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DNM1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,ECEL1,EDA,EDN1,EGR2,EME1,EPAS1,EPHB3,ERC2,EXOC3L1,F2RL3,FAM107A,FAM13A,FAS,FBXO6,FCN1,FGD5,FLT3LG,FSTL4,FYB1,G0S2,GABRA3,GADD45B,GAL3ST4,GAREM1,GBP1,GBP2,GBP5,GBP7,GFRA2,GHRL,GJD3,GLDN,GLIPR2,GNG2,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GTPBP1,GTSE1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,HORMAD1,HRH2,HSH2D,HTRA1,ICAM1,IFI27,IFI35,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAD2L1,MAML3,MCF2L,MCOLN2,MCTP2,MEFV,MERTK,MIR503,MMP9,MRAS,MTSS1,MUC1,MVP,MYOF,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRGN,NRK,NRP1,NUCB1,NUF2,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,ONECUT2,OPTN,OR2I1P,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PROK2,PRRT2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RIPK2,RNF213,RSAD2,RSU1,RXFP1,S100A13,S1PR1,SCIMP,SCN4B,SECTM1,SEMA6B,SEPTIN4,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLC12A3,SLC16A10,SLC20A1,SOCS1,SOX17,SPC24,SPC25,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYT1,SYT6,TAGAP,TANK,TGM2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TPCN1,TRABD2A,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYRO3,UBD,VCAM1,VEGFC,VRK2,WDR76,WWP1,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0051347","Term":"positive regulation of transferase activity","Annotated":328,"Significant":25,"Expected":19.81,"Rank in p.value_classic":1564,"p.value_elim":0.1338,"p.value_classic":0.13646,"genes":"AGT,AURKB,CCL5,CD40,CD74,CHTF18,CLSPN,CSF1,DSCC1,EDN1,HLA-DRB1,JAK2,KLF4,LRRK2,MERTK,MMD,NCF1,PKIB,PLAAT4,RALB,RAPGEF2,SERINC5,SLC11A1,TNFRSF11A,TYRO3"} {"GO.ID":"GO:0018958","Term":"phenol-containing compound metabolic process","Annotated":71,"Significant":7,"Expected":4.29,"Rank in p.value_classic":1557,"p.value_elim":0.13453,"p.value_classic":0.13581,"genes":"CTNS,EPAS1,GCH1,NPR1,OCA2,RAPGEF2,SLC16A10"} {"GO.ID":"GO:0002200","Term":"somatic diversification of immune receptors","Annotated":71,"Significant":7,"Expected":4.29,"Rank in p.value_classic":1558,"p.value_elim":0.13453,"p.value_classic":0.13581,"genes":"BCL6,CD28,EXO1,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:0051353","Term":"positive regulation of oxidoreductase activity","Annotated":33,"Significant":4,"Expected":1.99,"Rank in p.value_classic":1556,"p.value_elim":0.13469,"p.value_classic":0.1356,"genes":"AGT,DHFR,EDN1,GCH1"} {"GO.ID":"GO:0010660","Term":"regulation of muscle cell apoptotic process","Annotated":58,"Significant":6,"Expected":3.5,"Rank in p.value_classic":1560,"p.value_elim":0.13487,"p.value_classic":0.13604,"genes":"CAMK2D,EDN1,GCH1,IL12A,JAK2,ZC3H12A"} {"GO.ID":"GO:0042310","Term":"vasoconstriction","Annotated":58,"Significant":6,"Expected":3.5,"Rank in p.value_classic":1561,"p.value_elim":0.13487,"p.value_classic":0.13604,"genes":"AGT,CD38,COMP,CYSLTR1,EDN1,HRH2"} {"GO.ID":"GO:0061180","Term":"mammary gland epithelium development","Annotated":58,"Significant":6,"Expected":3.5,"Rank in p.value_classic":1562,"p.value_elim":0.13487,"p.value_classic":0.13604,"genes":"CSF1,IQGAP3,JAK2,LBH,LRP5,PML"} {"GO.ID":"GO:0062208","Term":"positive regulation of pattern recognition receptor signaling pathway","Annotated":58,"Significant":6,"Expected":3.5,"Rank in p.value_classic":1563,"p.value_elim":0.13487,"p.value_classic":0.13604,"genes":"DDX60,GBP2,GBP5,IFI35,RSAD2,TICAM2"} {"GO.ID":"GO:0006638","Term":"neutral lipid metabolic process","Annotated":98,"Significant":9,"Expected":5.92,"Rank in p.value_classic":1565,"p.value_elim":0.1356,"p.value_classic":0.13709,"genes":"ACSL1,C3,DGAT2,G6PC1,GK,LPL,PLAAT3,PLB1,PNPLA3"} {"GO.ID":"GO:0098656","Term":"monoatomic anion transmembrane transport","Annotated":98,"Significant":9,"Expected":5.92,"Rank in p.value_classic":1566,"p.value_elim":0.1356,"p.value_classic":0.13709,"genes":"ABCB1,ABCC11,ANO4,APOL1,CLIC5,GABRA3,OCA2,SLC12A3,SLC4A7"} {"GO.ID":"GO:0042509","Term":"regulation of tyrosine phosphorylation of STAT protein","Annotated":54,"Significant":13,"Expected":3.26,"Rank in p.value_classic":300,"p.value_elim":0.13664,"p.value_classic":0.00001,"genes":"CCL5,CD40,IL12A,IL15,IL22RA2,IL31RA,JAK2,LYN,OSM,PARP14,PARP9,SOCS1,TNFSF18"} {"GO.ID":"GO:0050714","Term":"positive regulation of protein secretion","Annotated":112,"Significant":10,"Expected":6.76,"Rank in p.value_classic":1568,"p.value_elim":0.13725,"p.value_classic":0.13886,"genes":"ADAM8,ATP13A2,CD38,GHRL,HCAR2,HLA-DRB1,JAK2,P2RX7,SRI,VEGFC"} {"GO.ID":"GO:0032412","Term":"regulation of monoatomic ion transmembrane transporter activity","Annotated":154,"Significant":13,"Expected":9.3,"Rank in p.value_classic":1569,"p.value_elim":0.13726,"p.value_classic":0.13912,"genes":"ABCB1,ANK2,ATP1B2,CAMK2D,CRHBP,CTSS,EDN1,KCNE5,MMP9,SCN4B,SRI,TESC,TRDN"} {"GO.ID":"GO:0019220","Term":"regulation of phosphate metabolic process","Annotated":964,"Significant":82,"Expected":58.22,"Rank in p.value_classic":483,"p.value_elim":0.13799,"p.value_classic":0.00089,"genes":"AGT,BANK1,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PDK4,PID1,PKIB,PKMYT1,PLEK,PPM1E,RALB,RAPGEF2,RIPK2,SLAMF8,SLC11A1,SLC2A6,SOCS1,SPTBN4,STAP1,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0001783","Term":"B cell apoptotic process","Annotated":25,"Significant":6,"Expected":1.51,"Rank in p.value_classic":600,"p.value_elim":0.13816,"p.value_classic":0.00313,"genes":"AURKB,BCL6,CD74,LYN,PDCD1,TNFRSF21"} {"GO.ID":"GO:0090075","Term":"relaxation of muscle","Annotated":25,"Significant":6,"Expected":1.51,"Rank in p.value_classic":601,"p.value_elim":0.13816,"p.value_classic":0.00313,"genes":"CAMK2D,KCNJ2,P2RX4,PDE4B,SRI,TIFAB"} {"GO.ID":"GO:0046642","Term":"negative regulation of alpha-beta T cell proliferation","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1570,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CD274,TNFRSF14"} {"GO.ID":"GO:0001973","Term":"G protein-coupled adenosine receptor signaling pathway","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1571,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"ADORA3,NECAB2"} {"GO.ID":"GO:0009159","Term":"deoxyribonucleoside monophosphate catabolic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1572,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"DPYS,TYMP"} {"GO.ID":"GO:0051987","Term":"positive regulation of attachment of spindle microtubules to kinetochore","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1573,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"AURKB,BIRC5"} {"GO.ID":"GO:0032060","Term":"bleb assembly","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1574,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"ANLN,P2RX7"} {"GO.ID":"GO:0075509","Term":"endocytosis involved in viral entry into host cell","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1575,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CTSL,TPCN1"} {"GO.ID":"GO:0046940","Term":"nucleoside monophosphate phosphorylation","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1576,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"AK1,CMPK2"} {"GO.ID":"GO:0045956","Term":"positive regulation of calcium ion-dependent exocytosis","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1577,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"STX1A,SYT1"} {"GO.ID":"GO:0070294","Term":"renal sodium ion absorption","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1578,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"EDN1,SLC12A3"} {"GO.ID":"GO:0010819","Term":"regulation of T cell chemotaxis","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1579,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CCL5,CXCL10"} {"GO.ID":"GO:2000035","Term":"regulation of stem cell division","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1580,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"LBH,SOX17"} {"GO.ID":"GO:1905522","Term":"negative regulation of macrophage migration","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1581,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"SLAMF8,STAP1"} {"GO.ID":"GO:0010561","Term":"negative regulation of glycoprotein biosynthetic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1582,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"HBEGF,JAK3"} {"GO.ID":"GO:0034145","Term":"positive regulation of toll-like receptor 4 signaling pathway","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1583,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"IFI35,TICAM2"} {"GO.ID":"GO:0051000","Term":"positive regulation of nitric-oxide synthase activity","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1584,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0032490","Term":"detection of molecule of bacterial origin","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1585,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"C4B,NOD2"} {"GO.ID":"GO:0032494","Term":"response to peptidoglycan","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1586,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"NOD2,RIPK2"} {"GO.ID":"GO:0033189","Term":"response to vitamin A","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1587,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CYP1A1,TYMS"} {"GO.ID":"GO:0141086","Term":"negative regulation of inflammasome-mediated signaling pathway","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1588,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"MEFV,TRIM31"} {"GO.ID":"GO:0097067","Term":"cellular response to thyroid hormone stimulus","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1589,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CTSL,CTSS"} {"GO.ID":"GO:0097048","Term":"dendritic cell apoptotic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1590,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"LYN,RAPGEF2"} {"GO.ID":"GO:0070586","Term":"cell-cell adhesion involved in gastrulation","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1591,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"IL1RN,KLF4"} {"GO.ID":"GO:0042117","Term":"monocyte activation","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1592,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CSF1,DYSF"} {"GO.ID":"GO:0048302","Term":"regulation of isotype switching to IgG isotypes","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1593,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CD28,TBX21"} {"GO.ID":"GO:0070601","Term":"centromeric sister chromatid cohesion","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1594,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"BUB1B,MEIKIN"} {"GO.ID":"GO:0010944","Term":"negative regulation of transcription by competitive promoter binding","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1595,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"BHLHE41,MUC1"} {"GO.ID":"GO:0042753","Term":"positive regulation of circadian rhythm","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1596,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"BMAL2,GHRL"} {"GO.ID":"GO:0032725","Term":"positive regulation of granulocyte macrophage colony-stimulating factor production","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1597,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CD80,LILRA2"} {"GO.ID":"GO:0046325","Term":"negative regulation of glucose import","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1598,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"APPL2,PID1"} {"GO.ID":"GO:2000774","Term":"positive regulation of cellular senescence","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1599,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"B2M,HLA-G"} {"GO.ID":"GO:0033690","Term":"positive regulation of osteoblast proliferation","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1600,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"LRP5,TMEM119"} {"GO.ID":"GO:0051280","Term":"negative regulation of release of sequestered calcium ion into cytosol","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1601,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"SRI,TRDN"} {"GO.ID":"GO:0016114","Term":"terpenoid biosynthetic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1602,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CYP1A1,DHRS9"} {"GO.ID":"GO:0033629","Term":"negative regulation of cell adhesion mediated by integrin","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1603,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"MUC1,PDE3B"} {"GO.ID":"GO:0042541","Term":"hemoglobin biosynthetic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1604,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"ALAS1,KLF4"} {"GO.ID":"GO:0042532","Term":"negative regulation of tyrosine phosphorylation of STAT protein","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1605,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"PARP14,SOCS1"} {"GO.ID":"GO:0021511","Term":"spinal cord patterning","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1606,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CHRD,IFT122"} {"GO.ID":"GO:2000668","Term":"regulation of dendritic cell apoptotic process","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1607,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"LYN,RAPGEF2"} {"GO.ID":"GO:0051549","Term":"positive regulation of keratinocyte migration","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1608,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"HBEGF,MMP9"} {"GO.ID":"GO:0071696","Term":"ectodermal placode development","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1609,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"EDA,NRP1"} {"GO.ID":"GO:0035865","Term":"cellular response to potassium ion","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1610,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CRHBP,KCNJ10"} {"GO.ID":"GO:0051608","Term":"histamine transport","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1611,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"EDN1,LYN"} {"GO.ID":"GO:0035810","Term":"positive regulation of urine volume","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1612,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"EDN1,NPR1"} {"GO.ID":"GO:1902514","Term":"regulation of calcium ion transmembrane transport via high voltage-gated calcium channel","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1613,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"CAMK2D,PDE4B"} {"GO.ID":"GO:0045836","Term":"positive regulation of meiotic nuclear division","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1614,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"DAZL,NPM2"} {"GO.ID":"GO:0035588","Term":"G protein-coupled purinergic receptor signaling pathway","Annotated":11,"Significant":2,"Expected":0.66,"Rank in p.value_classic":1615,"p.value_elim":0.13908,"p.value_classic":0.13966,"genes":"ADORA3,NECAB2"} {"GO.ID":"GO:0031644","Term":"regulation of nervous system process","Annotated":85,"Significant":8,"Expected":5.13,"Rank in p.value_classic":1616,"p.value_elim":0.13911,"p.value_classic":0.14053,"genes":"DLGAP3,EGR2,GHRL,LRRK2,STX1A,SYNE1,TNFRSF21,TYMP"} {"GO.ID":"GO:0051174","Term":"regulation of phosphorus metabolic process","Annotated":965,"Significant":82,"Expected":58.28,"Rank in p.value_classic":486,"p.value_elim":0.14002,"p.value_classic":0.00092,"genes":"AGT,BANK1,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PDK4,PID1,PKIB,PKMYT1,PLEK,PPM1E,RALB,RAPGEF2,RIPK2,SLAMF8,SLC11A1,SLC2A6,SOCS1,SPTBN4,STAP1,STAT2,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0090132","Term":"epithelium migration","Annotated":271,"Significant":21,"Expected":16.37,"Rank in p.value_classic":1624,"p.value_elim":0.14149,"p.value_classic":0.14399,"genes":"AGT,AMOT,ANLN,CD40,CDH5,CEACAM1,EDN1,ENPP2,GLIPR2,GLUL,HBEGF,KITLG,KLF4,MIR503,MMP9,NRP1,P2RX4,PRKX,PXN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0010631","Term":"epithelial cell migration","Annotated":271,"Significant":21,"Expected":16.37,"Rank in p.value_classic":1625,"p.value_elim":0.14149,"p.value_classic":0.14399,"genes":"AGT,AMOT,ANLN,CD40,CDH5,CEACAM1,EDN1,ENPP2,GLIPR2,GLUL,HBEGF,KITLG,KLF4,MIR503,MMP9,NRP1,P2RX4,PRKX,PXN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0035987","Term":"endodermal cell differentiation","Annotated":46,"Significant":5,"Expected":2.78,"Rank in p.value_classic":1619,"p.value_elim":0.14152,"p.value_classic":0.1426,"genes":"ITGA7,ITGB5,LAMB3,MMP9,SOX17"} {"GO.ID":"GO:0014743","Term":"regulation of muscle hypertrophy","Annotated":46,"Significant":5,"Expected":2.78,"Rank in p.value_classic":1620,"p.value_elim":0.14152,"p.value_classic":0.1426,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0022617","Term":"extracellular matrix disassembly","Annotated":46,"Significant":5,"Expected":2.78,"Rank in p.value_classic":1621,"p.value_elim":0.14152,"p.value_classic":0.1426,"genes":"ADAM8,ADAMTS15,CTSS,FSCN1,MMP9"} {"GO.ID":"GO:0045446","Term":"endothelial cell differentiation","Annotated":99,"Significant":9,"Expected":5.98,"Rank in p.value_classic":1623,"p.value_elim":0.14172,"p.value_classic":0.14327,"genes":"CDH5,CEACAM1,DLL1,ICAM1,MARVELD2,NRP1,RAPGEF2,S1PR1,SOX17"} {"GO.ID":"GO:0034308","Term":"primary alcohol metabolic process","Annotated":72,"Significant":7,"Expected":4.35,"Rank in p.value_classic":1622,"p.value_elim":0.14179,"p.value_classic":0.14312,"genes":"CYP1A1,DAB2,DGAT2,DHRS3,DHRS9,NAAA,PLB1"} {"GO.ID":"GO:0006820","Term":"monoatomic anion transport","Annotated":113,"Significant":10,"Expected":6.82,"Rank in p.value_classic":1639,"p.value_elim":0.143,"p.value_classic":0.14465,"genes":"ABCB1,ABCC11,ANO4,APOL1,ATP8B1,CLIC5,GABRA3,OCA2,SLC12A3,SLC4A7"} {"GO.ID":"GO:0070059","Term":"intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress","Annotated":59,"Significant":6,"Expected":3.56,"Rank in p.value_classic":1626,"p.value_elim":0.14301,"p.value_classic":0.14423,"genes":"BCL2L11,CASP4,CHAC1,LRRK2,PMAIP1,PML"} {"GO.ID":"GO:0051048","Term":"negative regulation of secretion","Annotated":127,"Significant":11,"Expected":7.67,"Rank in p.value_classic":1640,"p.value_elim":0.14332,"p.value_classic":0.14508,"genes":"ASIC1,CD74,CEACAM1,CRHBP,EDN1,GHRL,HLA-F,IL12A,OSM,RSAD2,TIFAB"} {"GO.ID":"GO:0048639","Term":"positive regulation of developmental growth","Annotated":127,"Significant":11,"Expected":7.67,"Rank in p.value_classic":1641,"p.value_elim":0.14332,"p.value_classic":0.14508,"genes":"AGR2,CDK1,CSF1,DLL1,EDN1,GHRL,IL7,NRP1,PIM1,SPTBN4,SYT1"} {"GO.ID":"GO:0044058","Term":"regulation of digestive system process","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1627,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"GHRL,TIFAB,TYMP"} {"GO.ID":"GO:1900017","Term":"positive regulation of cytokine production involved in inflammatory response","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1628,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"GBP5,NOD2,TICAM2"} {"GO.ID":"GO:0045624","Term":"positive regulation of T-helper cell differentiation","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1629,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"CD80,IL12RB1,RIPK2"} {"GO.ID":"GO:0060314","Term":"regulation of ryanodine-sensitive calcium-release channel activity","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1630,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0060339","Term":"negative regulation of type I interferon-mediated signaling pathway","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1631,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"NLRC5,OAS3,STAT2"} {"GO.ID":"GO:0035929","Term":"steroid hormone secretion","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1632,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"AGT,DAB2,GHRL"} {"GO.ID":"GO:0030878","Term":"thyroid gland development","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1633,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"CTNS,EDN1,HESX1"} {"GO.ID":"GO:0038096","Term":"Fc-gamma receptor signaling pathway involved in phagocytosis","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1634,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"APPL2,LYN,PLPP4"} {"GO.ID":"GO:0070233","Term":"negative regulation of T cell apoptotic process","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1635,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"CCL5,IDO1,JAK3"} {"GO.ID":"GO:0002433","Term":"immune response-regulating cell surface receptor signaling pathway involved in phagocytosis","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1636,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"APPL2,LYN,PLPP4"} {"GO.ID":"GO:0032753","Term":"positive regulation of interleukin-4 production","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1637,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"CD28,HLA-E,IRF4"} {"GO.ID":"GO:1903524","Term":"positive regulation of blood circulation","Annotated":22,"Significant":3,"Expected":1.33,"Rank in p.value_classic":1638,"p.value_elim":0.14355,"p.value_classic":0.14434,"genes":"EDN1,GCH1,GHRL"} {"GO.ID":"GO:0048732","Term":"gland development","Annotated":361,"Significant":27,"Expected":21.8,"Rank in p.value_classic":1643,"p.value_elim":0.14375,"p.value_classic":0.14667,"genes":"BCL2L11,CEACAM1,CSF1,CTNS,CYP1A1,DNAAF1,E2F8,EDA,EDN1,EPHB3,FGL1,HESX1,HGF,IGF2R,IQGAP3,JAK2,LBH,LRP5,NRP1,OAS2,ONECUT2,PML,POLB,RXFP1,TGM2,TNFRSF11A,TYMS"} {"GO.ID":"GO:0010720","Term":"positive regulation of cell development","Annotated":381,"Significant":36,"Expected":23.01,"Rank in p.value_classic":657,"p.value_elim":0.14526,"p.value_classic":0.00509,"genes":"ADAM8,BCL6,BTN2A2,CD101,CD74,CD80,CD83,CDH5,CSF1,CX3CR1,CYLD,CYSLTR1,EGR2,HAPLN3,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL4I1,IL7,KITLG,LTA,LYN,NRP1,PLXNA2,RIPK2,SOCS1,TESC,TGM2,TNFRSF11A,VCAN,VEGFC,WDR62,XRCC2"} {"GO.ID":"GO:0002444","Term":"myeloid leukocyte mediated immunity","Annotated":86,"Significant":8,"Expected":5.19,"Rank in p.value_classic":1648,"p.value_elim":0.14583,"p.value_classic":0.1473,"genes":"C3,CX3CR1,HLA-E,LYN,NR4A3,S100A13,STAP1,TICAM2"} {"GO.ID":"GO:0008016","Term":"regulation of heart contraction","Annotated":148,"Significant":20,"Expected":8.94,"Rank in p.value_classic":456,"p.value_elim":0.14583,"p.value_classic":0.00058,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CXADR,EDN1,EPAS1,GCH1,GJD3,HBEGF,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SPTBN4,SRI,TRDN,ZC3H12A"} {"GO.ID":"GO:0050819","Term":"negative regulation of coagulation","Annotated":34,"Significant":4,"Expected":2.05,"Rank in p.value_classic":1644,"p.value_elim":0.14584,"p.value_classic":0.1468,"genes":"CEACAM1,EDN1,SERPING1,THBD"} {"GO.ID":"GO:0048483","Term":"autonomic nervous system development","Annotated":34,"Significant":4,"Expected":2.05,"Rank in p.value_classic":1645,"p.value_elim":0.14584,"p.value_classic":0.1468,"genes":"EGR2,KIF26A,NRP1,VCAM1"} {"GO.ID":"GO:0045191","Term":"regulation of isotype switching","Annotated":34,"Significant":4,"Expected":2.05,"Rank in p.value_classic":1646,"p.value_elim":0.14584,"p.value_classic":0.1468,"genes":"BCL6,CD28,PARP3,TBX21"} {"GO.ID":"GO:0002691","Term":"regulation of cellular extravasation","Annotated":34,"Significant":4,"Expected":2.05,"Rank in p.value_classic":1647,"p.value_elim":0.14584,"p.value_classic":0.1468,"genes":"ADAM8,ICAM1,LYVE1,PTGER4"} {"GO.ID":"GO:0016477","Term":"cell migration","Annotated":1240,"Significant":107,"Expected":74.89,"Rank in p.value_classic":353,"p.value_elim":0.14601,"p.value_classic":0.00008,"genes":"ADAM8,ADORA3,AGT,AMOT,ANLN,APPL2,ASB2,ASCL2,ATP1B2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD274,CD300H,CD40,CD74,CDH5,CDK1,CEACAM1,CELSR1,CHRD,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,DAB1,DAB2,EDN1,ENPP2,EPHB3,FAM107A,FMNL2,FSCN1,GLIPR2,GLUL,GPR183,HBEGF,HGF,HSD3B7,ICAM1,IFITM1,IL12A,ITGA7,ITGB5,JAK2,KIF26A,KITLG,KLF4,KLRK1,LRP5,LRRK2,LYN,LYVE1,MCOLN2,MDGA1,MERTK,MIR503,MMP9,MTUS1,NLRP12,NOD2,NR4A3,NRCAM,NRP1,ONECUT2,P2RX4,PADI2,PARP9,PDE4B,PLXNA2,PML,PRKX,PTGER4,PTPRU,PXN,RAPGEF2,S1PR1,SDC2,SDC3,SELL,SEMA6B,SEPTIN4,SGPL1,SLAMF1,SLAMF8,SOX17,STAP1,STMN1,TBX21,TMSB10,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VCAM1,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:1905952","Term":"regulation of lipid localization","Annotated":125,"Significant":14,"Expected":7.55,"Rank in p.value_classic":851,"p.value_elim":0.14604,"p.value_classic":0.01855,"genes":"ACSL1,AGT,C3,DAB2,EDN1,EEPD1,GHRL,LPL,OSBPL6,P2RX4,P2RX7,TNFRSF11A,TTC39B,ZC3H12A"} {"GO.ID":"GO:0045859","Term":"regulation of protein kinase activity","Annotated":407,"Significant":30,"Expected":24.58,"Rank in p.value_classic":1650,"p.value_elim":0.14628,"p.value_classic":0.14942,"genes":"AGT,CCL5,CCNA2,CCNE2,CCNF,CD40,CDC25A,CDC6,CDKN2C,CEACAM1,CLSPN,CSF1,DEPTOR,DTNBP1,EDN1,JAK2,LRP5,LRRK2,LYN,MMD,MVP,NCF1,PKIB,PKMYT1,PPM1E,RALB,RAPGEF2,SLC11A1,TNFRSF11A,WARS1"} {"GO.ID":"GO:0051051","Term":"negative regulation of transport","Annotated":332,"Significant":25,"Expected":20.05,"Rank in p.value_classic":1651,"p.value_elim":0.14692,"p.value_classic":0.14977,"genes":"APPL2,ASIC1,CAMK2D,CD300LF,CD74,CEACAM1,CRHBP,DERL3,DYSF,EDN1,GHRL,HLA-F,IL12A,KCNE5,LRRK2,MMP9,NECAB2,OSM,PID1,PLSCR1,PRRT2,RSAD2,SRI,TIFAB,TRDN"} {"GO.ID":"GO:1905954","Term":"positive regulation of lipid localization","Annotated":84,"Significant":11,"Expected":5.07,"Rank in p.value_classic":782,"p.value_elim":0.14694,"p.value_classic":0.01197,"genes":"ACSL1,C3,DAB2,EDN1,EEPD1,GHRL,LPL,P2RX4,P2RX7,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0070887","Term":"cellular response to chemical stimulus","Annotated":2140,"Significant":207,"Expected":129.25,"Rank in p.value_classic":71,"p.value_elim":0.14779,"p.value_classic":2.6e-13,"genes":"ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,AGR2,AGT,AIFM2,AIM2,APPL2,ATF3,ATP13A2,B2M,BCL2L11,BRCA1,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CBR3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD274,CD300H,CD300LF,CD40,CD69,CD74,CD80,CDC6,CDK1,CEACAM1,CMPK2,COLEC12,CRHBP,CSF1,CSF2RB,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB2,DERL3,DGAT2,DHFR,DTNBP1,E2F1,EDN1,EGR2,EPAS1,EPHX1,FAM107A,FAS,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GHRL,GNG2,GPR183,GRAMD1B,GSTK1,HBEGF,HELLS,HESX1,HGF,HLA-DPA1,HLA-DRB1,HSD3B7,ICAM1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IQGAP3,IRF1,IRF7,JAK2,JAK3,KCNJ10,KLF4,KLRK1,LBH,LILRA1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTC4S,LYN,MCM2,MCM7,MMP9,MRAS,MT2A,MTUS1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,NRP1,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLSCR4,PMAIP1,PML,PNPLA3,PPM1E,PTGER4,PXN,PYHIN1,RAB20,RALB,RAPGEF2,RELB,RIPK2,RUFY4,RXFP1,S1PR1,SBNO2,SCIMP,SESN3,SIDT2,SLAMF1,SLAMF8,SLC11A1,SLC12A3,SLC2A5,SNX10,SOCS1,SOX17,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,SYT1,SYT6,TANK,TBX21,TESC,TGM2,TICAM2,TIFA,TIFAB,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,VEGFC,VRK2,XRN1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0002275","Term":"myeloid cell activation involved in immune response","Annotated":77,"Significant":12,"Expected":4.65,"Rank in p.value_classic":556,"p.value_elim":0.1482,"p.value_classic":0.00211,"genes":"CX3CR1,DYSF,IFI35,KARS1,LILRA2,LYN,NMI,NR4A3,S100A13,SBNO2,SLAMF1,SUCNR1"} {"GO.ID":"GO:0000280","Term":"nuclear division","Annotated":373,"Significant":44,"Expected":22.53,"Rank in p.value_classic":304,"p.value_elim":0.14842,"p.value_classic":0.00002,"genes":"ANLN,AURKB,BCL2L11,BIRC5,BUB1B,CCNE2,CD28,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,DAZL,DMC1,EDN1,EME1,EML4,HORMAD1,KIF11,KIF18B,KIF23,LRP5,MAD2L1,MEIKIN,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,PKMYT1,PRC1,RAD54B,RAD54L,SPC24,SPC25,TDRD9,TOP2A,UHRF1,ZWINT"} {"GO.ID":"GO:0006937","Term":"regulation of muscle contraction","Annotated":114,"Significant":10,"Expected":6.89,"Rank in p.value_classic":1653,"p.value_elim":0.14887,"p.value_classic":0.15057,"genes":"ANK2,CAMK2D,EDN1,GHRL,KCNJ2,P2RX4,PDE4B,PROK2,SRI,ZC3H12A"} {"GO.ID":"GO:0030879","Term":"mammary gland development","Annotated":114,"Significant":10,"Expected":6.89,"Rank in p.value_classic":1654,"p.value_elim":0.14887,"p.value_classic":0.15057,"genes":"BCL2L11,CSF1,IQGAP3,JAK2,LBH,LRP5,OAS2,PML,RXFP1,TNFRSF11A"} {"GO.ID":"GO:0032101","Term":"regulation of response to external stimulus","Annotated":899,"Significant":123,"Expected":54.3,"Rank in p.value_classic":25,"p.value_elim":0.14895,"p.value_classic":1.6e-18,"genes":"ACOD1,ADAM8,AGT,AIM2,APOBEC3G,APPL2,AURKB,BCL6,C3,CARD16,CASP4,CCL5,CCL7,CD274,CD28,CD300LF,CD74,CDH5,CEACAM1,CFH,CLEC6A,COLEC12,CSF1,CTSS,CX3CR1,CXCL10,CYLD,DDX60,DTX3L,EDN1,ENPP4,FCN1,FGL2,GBP2,GBP5,GHRL,GPR183,GPR31,GRAMD4,GRIN3A,GSDMD,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL22RA2,IL27,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,KLRK1,KREMEN1,LAG3,LILRA2,LPL,LRRK2,LTA,LYN,MEFV,MMP9,MTUS1,NCF1,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,OPTN,OSM,P2RX4,PADI2,PARP14,PARP9,PLSCR1,PTGER4,PYHIN1,RIPK2,RSAD2,RTN4RL1,S1PR1,SBNO2,SCARF1,SCIMP,SEMA6B,SERPING1,SLAMF1,SLAMF6,SLAMF8,STAP1,STAT1,STAT2,SUCNR1,THBD,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:1904029","Term":"regulation of cyclin-dependent protein kinase activity","Annotated":73,"Significant":7,"Expected":4.41,"Rank in p.value_classic":1655,"p.value_elim":0.14924,"p.value_classic":0.15062,"genes":"CCNA2,CCNE2,CCNF,CDC25A,CDC6,CDKN2C,PKMYT1"} {"GO.ID":"GO:0030072","Term":"peptide hormone secretion","Annotated":171,"Significant":14,"Expected":10.33,"Rank in p.value_classic":1656,"p.value_elim":0.15034,"p.value_classic":0.15242,"genes":"CCL5,CD38,CRHBP,EDN1,EXOC3L1,GHRL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SLC16A10,SRI,STX1A"} {"GO.ID":"GO:0050708","Term":"regulation of protein secretion","Annotated":200,"Significant":16,"Expected":12.08,"Rank in p.value_classic":1658,"p.value_elim":0.15064,"p.value_classic":0.15289,"genes":"ADAM8,ATP13A2,CCL5,CD38,GHRL,HCAR2,HLA-DRB1,IL12A,JAK2,LRP5,P2RX7,RSAD2,SIDT2,SRI,STX1A,VEGFC"} {"GO.ID":"GO:0007405","Term":"neuroblast proliferation","Annotated":60,"Significant":6,"Expected":3.62,"Rank in p.value_classic":1657,"p.value_elim":0.15136,"p.value_classic":0.15263,"genes":"CX3CR1,HAPLN3,LRRK2,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0001909","Term":"leukocyte mediated cytotoxicity","Annotated":104,"Significant":24,"Expected":6.28,"Rank in p.value_classic":148,"p.value_elim":0.15159,"p.value_classic":9e-09,"genes":"B2M,CD1A,CD1C,CEACAM1,CX3CR1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,RNF19B,SLAMF6,SLAMF7,STAP1,TAP2"} {"GO.ID":"GO:0017157","Term":"regulation of exocytosis","Annotated":157,"Significant":13,"Expected":9.48,"Rank in p.value_classic":1659,"p.value_elim":0.15207,"p.value_classic":0.15408,"genes":"ATP13A2,CADPS2,CEACAM1,DTNBP1,HLA-F,LRRK2,LYN,S100A10,SEPTIN4,STX1A,SV2B,SYT1,SYT6"} {"GO.ID":"GO:1904659","Term":"glucose transmembrane transport","Annotated":87,"Significant":8,"Expected":5.25,"Rank in p.value_classic":1660,"p.value_elim":0.15271,"p.value_classic":0.15423,"genes":"APPL2,C3,CTNS,EDN1,NR4A3,PID1,SLC2A5,SLC2A6"} {"GO.ID":"GO:0010721","Term":"negative regulation of cell development","Annotated":227,"Significant":26,"Expected":13.71,"Rank in p.value_classic":511,"p.value_elim":0.15273,"p.value_classic":0.00125,"genes":"APPL2,ASCL2,B2M,BCL6,CD74,CEACAM1,CTLA4,DAB1,DYNLT1,FGL2,FSTL4,HLA-G,IRF1,JAK3,LAG3,LILRB3,LYN,NRP1,RAPGEF2,SEMA6B,SOCS1,TBX21,TMEM176A,TMEM176B,TNFAIP6,ZC3H12A"} {"GO.ID":"GO:0098742","Term":"cell-cell adhesion via plasma-membrane adhesion molecules","Annotated":186,"Significant":15,"Expected":11.23,"Rank in p.value_classic":1661,"p.value_elim":0.15299,"p.value_classic":0.15518,"genes":"CDH5,CEACAM1,CELSR1,CXADR,DAB1,ICAM1,IL1RN,KLF4,MDGA1,MPZL2,PCDH12,PCDHGC3,SCARF1,SELL,VCAM1"} {"GO.ID":"GO:0045787","Term":"positive regulation of cell cycle","Annotated":279,"Significant":28,"Expected":16.85,"Rank in p.value_classic":669,"p.value_elim":0.15347,"p.value_classic":0.00571,"genes":"AURKB,BCL2L11,BIRC5,CCNE2,CD28,CDC25A,CDC6,CDCA5,CDK1,CYP1A1,DAZL,DTL,E2F8,EDN1,FEN1,KIF23,LRP5,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUSAP1,OVOL1,PLSCR1,RRM2,TAL1"} {"GO.ID":"GO:0051017","Term":"actin filament bundle assembly","Annotated":143,"Significant":12,"Expected":8.64,"Rank in p.value_classic":1662,"p.value_elim":0.15349,"p.value_classic":0.15543,"genes":"FAM107A,FSCN1,ITGB5,MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0045766","Term":"positive regulation of angiogenesis","Annotated":143,"Significant":12,"Expected":8.64,"Rank in p.value_classic":1663,"p.value_elim":0.15349,"p.value_classic":0.15543,"genes":"BRCA1,C3,CD40,CDH5,CX3CR1,CYSLTR1,DLL1,GHRL,KLF4,NRP1,VEGFC,ZC3H12A"} {"GO.ID":"GO:0008217","Term":"regulation of blood pressure","Annotated":129,"Significant":11,"Expected":7.79,"Rank in p.value_classic":1664,"p.value_elim":0.15447,"p.value_classic":0.15632,"genes":"AGT,DLL1,EDN1,ERAP2,GCH1,LRP5,NPR1,P2RX4,SLC2A5,SUCNR1,VEGFC"} {"GO.ID":"GO:0043277","Term":"apoptotic cell clearance","Annotated":45,"Significant":10,"Expected":2.72,"Rank in p.value_classic":410,"p.value_elim":0.15458,"p.value_classic":0.00028,"genes":"C2,C3,C4A,C4B,CD300LF,FCN1,MERTK,TGM2,TYRO3,XKR6"} {"GO.ID":"GO:0070665","Term":"positive regulation of leukocyte proliferation","Annotated":133,"Significant":27,"Expected":8.03,"Rank in p.value_classic":157,"p.value_elim":0.15472,"p.value_classic":2e-08,"genes":"BCL6,CCL5,CD274,CD28,CD38,CD74,CD80,CSF1,CSF2RB,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-E,IL12A,IL12RB1,IL15,IL7,JAK2,KITLG,LYN,PDCD1LG2,RIPK2,SLAMF1,TNFSF13B,VCAM1"} {"GO.ID":"GO:0048585","Term":"negative regulation of response to stimulus","Annotated":1398,"Significant":122,"Expected":84.43,"Rank in p.value_classic":297,"p.value_elim":0.15569,"p.value_classic":0.00001,"genes":"ACOD1,AGT,AIM2,AMER1,APPL2,ASCL2,ATF3,AURKB,BANK1,BCL6,BRCA1,BTN2A2,CARD16,CASTOR1,CCL5,CD300LF,CD74,CD80,CDH5,CEACAM1,CHAC1,CHRD,CISH,CR1L,CRHBP,CX3CR1,CYLD,DAB1,DAB2,DEPTOR,DHRS3,DKK2,DLL1,EDN1,FGL2,FSTL4,GBP1,GBP7,GHRL,GPR31,GRAMD4,GRIN3A,HELLS,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,HTRA1,ICAM1,IFI35,IFT122,IL12A,IL1RN,IL22RA2,IL4I1,IL7,IRF4,JAK3,KIF26A,KLF4,KLRK1,KREMEN1,LBH,LILRA2,LITAF,LRRK2,LYN,MEFV,MIR503,MMP9,MUC1,MVP,MYOZ2,NECAB2,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,ONECUT2,OPTN,P2RX7,PADI2,PARP14,PARP3,PDCD1,PDE3B,PDE4B,PID1,PLEK,PTGER4,PTPRU,RGS18,RMI2,RNF213,RTN4RL1,SEMA6B,SERPING1,SESN3,SLAMF1,SLAMF8,SOCS1,SOX17,STAP1,STAT1,STAT2,STMN1,TANK,TBX21,THBD,TNFAIP6,TNFRSF14,TRABD2A,TRAFD1,TRIM31,TSPAN15,TYRO3,ZC3H12A"} {"GO.ID":"GO:0090130","Term":"tissue migration","Annotated":275,"Significant":21,"Expected":16.61,"Rank in p.value_classic":1677,"p.value_elim":0.15652,"p.value_classic":0.15921,"genes":"AGT,AMOT,ANLN,CD40,CDH5,CEACAM1,EDN1,ENPP2,GLIPR2,GLUL,HBEGF,KITLG,KLF4,MIR503,MMP9,NRP1,P2RX4,PRKX,PXN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0009967","Term":"positive regulation of signal transduction","Annotated":1315,"Significant":112,"Expected":79.42,"Rank in p.value_classic":358,"p.value_elim":0.15677,"p.value_classic":0.00009,"genes":"ADAM8,AGR2,AGT,AMER1,APOL3,APPL2,ATF3,AURKB,BANK1,BCL2L11,BIRC5,C3,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD40,CD74,CD80,CDH5,CIBAR1,CLEC6A,CSF1,CTNS,CTSL,CTSS,CX3CR1,CYLD,DAB2,DDX60,DKK2,DLL1,EDA,EDN1,F2RL3,FAS,G0S2,GADD45B,GAREM1,GBP2,GBP5,GHRL,GLIPR2,GPR183,HBEGF,HGF,HLA-DRB1,ICAM1,IFI35,IFIT5,IL7,IQGAP3,IRF7,JAK2,KITLG,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MMP9,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OSM,P2RX4,P2RX7,PARP14,PARP9,PIM1,PMAIP1,PML,PYHIN1,RALB,RAPGEF2,RASGRF1,RIPK2,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SLAMF1,SLC20A1,STAMBPL1,STAP1,STX1A,TGM2,TICAM2,TIFA,TLR7,TNFAIP8L3,TNFRSF11A,TNFSF10,TRIM22,UBD,ZBP1,ZC3H12A"} {"GO.ID":"GO:0019748","Term":"secondary metabolic process","Annotated":35,"Significant":4,"Expected":2.11,"Rank in p.value_classic":1665,"p.value_elim":0.15732,"p.value_classic":0.15834,"genes":"CTNS,CYP1A1,OCA2,RAPGEF2"} {"GO.ID":"GO:0010656","Term":"negative regulation of muscle cell apoptotic process","Annotated":35,"Significant":4,"Expected":2.11,"Rank in p.value_classic":1666,"p.value_elim":0.15732,"p.value_classic":0.15834,"genes":"EDN1,GCH1,JAK2,ZC3H12A"} {"GO.ID":"GO:0032467","Term":"positive regulation of cytokinesis","Annotated":35,"Significant":4,"Expected":2.11,"Rank in p.value_classic":1667,"p.value_elim":0.15732,"p.value_classic":0.15834,"genes":"AURKB,BIRC5,CDC6,KIF23"} {"GO.ID":"GO:0141084","Term":"inflammasome-mediated signaling pathway","Annotated":35,"Significant":4,"Expected":2.11,"Rank in p.value_classic":1668,"p.value_elim":0.15732,"p.value_classic":0.15834,"genes":"GBP2,GBP5,MEFV,TRIM31"} {"GO.ID":"GO:0045746","Term":"negative regulation of Notch signaling pathway","Annotated":35,"Significant":4,"Expected":2.11,"Rank in p.value_classic":1669,"p.value_elim":0.15732,"p.value_classic":0.15834,"genes":"BCL6,CHAC1,DLL1,TSPAN15"} {"GO.ID":"GO:0097305","Term":"response to alcohol","Annotated":187,"Significant":15,"Expected":11.29,"Rank in p.value_classic":1678,"p.value_elim":0.15769,"p.value_classic":0.15993,"genes":"BRCA1,CCL7,CDK1,CRHBP,GNG2,GRAMD1B,GRIN3A,KLF4,POLB,PTGER4,SLC12A3,TNFRSF11A,TYMS,VCAM1,XRN1"} {"GO.ID":"GO:0002573","Term":"myeloid leukocyte differentiation","Annotated":205,"Significant":26,"Expected":12.38,"Rank in p.value_classic":403,"p.value_elim":0.15803,"p.value_classic":0.00026,"genes":"BATF2,BATF3,CD101,CD74,CEACAM1,CSF1,GPR183,HLA-DRB1,IL15,IL31RA,IRF4,IRF7,KITLG,LILRB3,LYN,MMP9,RELB,SBNO2,SH3PXD2A,SNX10,SOCS1,TAL1,TESC,TNFAIP6,TNFRSF11A,UBD"} {"GO.ID":"GO:0001990","Term":"regulation of systemic arterial blood pressure by hormone","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1670,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"AGT,EDN1,SUCNR1"} {"GO.ID":"GO:0043032","Term":"positive regulation of macrophage activation","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1671,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"KARS1,LRRK2,STAP1"} {"GO.ID":"GO:0044346","Term":"fibroblast apoptotic process","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1672,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"BCL2L11,CASP7,XRCC2"} {"GO.ID":"GO:0034694","Term":"response to prostaglandin","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1673,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"EDN1,GNG2,PTGER4"} {"GO.ID":"GO:0007187","Term":"G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1674,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"AGT,HRH2,SSTR2"} {"GO.ID":"GO:0036296","Term":"response to increased oxygen levels","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1675,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"CYP1A1,FAS,POLB"} {"GO.ID":"GO:0098810","Term":"neurotransmitter reuptake","Annotated":23,"Significant":3,"Expected":1.39,"Rank in p.value_classic":1676,"p.value_elim":0.15813,"p.value_classic":0.15898,"genes":"KCNJ10,SLC18A1,SLC6A12"} {"GO.ID":"GO:0045063","Term":"T-helper 1 cell differentiation","Annotated":23,"Significant":7,"Expected":1.39,"Rank in p.value_classic":413,"p.value_elim":0.15911,"p.value_classic":0.0003,"genes":"ASCL2,CD80,IL27,JAK3,RELB,RIPK2,TBX21"} {"GO.ID":"GO:0046394","Term":"carboxylic acid biosynthetic process","Annotated":246,"Significant":19,"Expected":14.86,"Rank in p.value_classic":1722,"p.value_elim":0.15915,"p.value_classic":0.16172,"genes":"ACOT4,BRCA1,CD74,CEACAM1,CYP1A1,DHFR,DHRS9,DSE,EDN1,GGT5,GLUL,HSD3B7,IDO1,LPL,LTC4S,OSBPL6,PDK4,SERINC5,SLC45A3"} {"GO.ID":"GO:0043368","Term":"positive T cell selection","Annotated":34,"Significant":7,"Expected":2.05,"Rank in p.value_classic":623,"p.value_elim":0.15933,"p.value_classic":0.00366,"genes":"CD74,CTSL,CYLD,IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0032102","Term":"negative regulation of response to external stimulus","Annotated":332,"Significant":44,"Expected":20.05,"Rank in p.value_classic":218,"p.value_elim":0.15959,"p.value_classic":6.9e-07,"genes":"ACOD1,AURKB,CARD16,CDH5,CEACAM1,CYLD,EDN1,FGL2,GHRL,GPR31,GRIN3A,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL22RA2,KLF4,KLRK1,KREMEN1,LILRA2,LYN,MEFV,NLRC5,NLRP12,NMI,NOD2,NRP1,OAS3,PADI2,PARP14,PTGER4,RTN4RL1,SEMA6B,SERPING1,SLAMF8,STAP1,STAT2,THBD,TNFAIP6,TRAFD1,TYRO3"} {"GO.ID":"GO:1900182","Term":"positive regulation of protein localization to nucleus","Annotated":88,"Significant":8,"Expected":5.31,"Rank in p.value_classic":1720,"p.value_elim":0.15974,"p.value_classic":0.16132,"genes":"CDK1,DTX3L,EDN1,JAK2,LIMK2,PARP9,PYHIN1,ZC3H12A"} {"GO.ID":"GO:0051702","Term":"biological process involved in interaction with symbiont","Annotated":88,"Significant":8,"Expected":5.31,"Rank in p.value_classic":1721,"p.value_elim":0.15974,"p.value_classic":0.16132,"genes":"APOL1,CCL5,CCL8,CX3CR1,IFI27,IGF2R,NOD2,ZC3H12A"} {"GO.ID":"GO:0043087","Term":"regulation of GTPase activity","Annotated":261,"Significant":20,"Expected":15.76,"Rank in p.value_classic":1725,"p.value_elim":0.15989,"p.value_classic":0.16255,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,EPHB3,FGD5,KLRK1,LRRK2,PLXNA2,RAPGEF2,RASGEF1C,RASGRF1,RSU1,S100A10,STMN1,TGM2,USP6NL"} {"GO.ID":"GO:0045765","Term":"regulation of angiogenesis","Annotated":243,"Significant":25,"Expected":14.68,"Rank in p.value_classic":695,"p.value_elim":0.1602,"p.value_classic":0.00641,"genes":"AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CYSLTR1,DLL1,E2F2,GHRL,GLUL,HLA-G,KLF4,MIR503,NPR1,NRP1,PDE3B,PML,STAT1,THBS2,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0034614","Term":"cellular response to reactive oxygen species","Annotated":130,"Significant":11,"Expected":7.85,"Rank in p.value_classic":1724,"p.value_elim":0.16021,"p.value_classic":0.16211,"genes":"CDK1,DHFR,EDN1,GCH1,HGF,IL18BP,KLF4,LRRK2,MMP9,NCF1,PXN"} {"GO.ID":"GO:0046606","Term":"negative regulation of centrosome cycle","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1680,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"BRCA1,CCNF"} {"GO.ID":"GO:0045628","Term":"regulation of T-helper 2 cell differentiation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1681,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"ASCL2,BCL6"} {"GO.ID":"GO:0009133","Term":"nucleoside diphosphate biosynthetic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1682,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"AK1,CMPK2"} {"GO.ID":"GO:0070365","Term":"hepatocyte differentiation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1683,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CYP1A1,E2F8"} {"GO.ID":"GO:0003096","Term":"renal sodium ion transport","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1684,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"EDN1,SLC12A3"} {"GO.ID":"GO:1902946","Term":"protein localization to early endosome","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1685,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"DTX3L,NRP1"} {"GO.ID":"GO:0010826","Term":"negative regulation of centrosome duplication","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1686,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"BRCA1,CCNF"} {"GO.ID":"GO:0060259","Term":"regulation of feeding behavior","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1687,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"GHRL,NR4A3"} {"GO.ID":"GO:0043301","Term":"negative regulation of leukocyte degranulation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1688,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CEACAM1,HLA-F"} {"GO.ID":"GO:0034112","Term":"positive regulation of homotypic cell-cell adhesion","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1689,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CCL5,JAK2"} {"GO.ID":"GO:0050884","Term":"neuromuscular process controlling posture","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1690,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"GCH1,PRRT2"} {"GO.ID":"GO:0016024","Term":"CDP-diacylglycerol biosynthetic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1691,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CDS1,LCLAT1"} {"GO.ID":"GO:0042481","Term":"regulation of odontogenesis","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1692,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CSF1,EDN1"} {"GO.ID":"GO:0033147","Term":"negative regulation of intracellular estrogen receptor signaling pathway","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1693,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"BRCA1,LBH"} {"GO.ID":"GO:0036006","Term":"cellular response to macrophage colony-stimulating factor stimulus","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1694,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CSF1,STAP1"} {"GO.ID":"GO:0002467","Term":"germinal center formation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1695,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"BCL6,TNFSF13B"} {"GO.ID":"GO:0033262","Term":"regulation of nuclear cell cycle DNA replication","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1696,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"BCL6,CDT1"} {"GO.ID":"GO:2000402","Term":"negative regulation of lymphocyte migration","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1697,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"KLRK1,PADI2"} {"GO.ID":"GO:0016322","Term":"neuron remodeling","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1698,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"C3,SCARF1"} {"GO.ID":"GO:0002227","Term":"innate immune response in mucosa","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1699,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"H2BC21,NOD2"} {"GO.ID":"GO:0036363","Term":"transforming growth factor beta activation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1700,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0046341","Term":"CDP-diacylglycerol metabolic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1701,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CDS1,LCLAT1"} {"GO.ID":"GO:0048291","Term":"isotype switching to IgG isotypes","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1702,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CD28,TBX21"} {"GO.ID":"GO:0034638","Term":"phosphatidylcholine catabolic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1703,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"ENPP2,PLB1"} {"GO.ID":"GO:0045348","Term":"positive regulation of MHC class II biosynthetic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1704,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CIITA,JAK2"} {"GO.ID":"GO:0002864","Term":"regulation of acute inflammatory response to antigenic stimulus","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1705,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"C3,HLA-E"} {"GO.ID":"GO:0051284","Term":"positive regulation of sequestering of calcium ion","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1706,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"SRI,TRDN"} {"GO.ID":"GO:0036158","Term":"outer dynein arm assembly","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1707,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"DNAAF1,LRRC61"} {"GO.ID":"GO:0071233","Term":"cellular response to leucine","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1708,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"SESN3,STAMBPL1"} {"GO.ID":"GO:0032645","Term":"regulation of granulocyte macrophage colony-stimulating factor production","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1709,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CD80,LILRA2"} {"GO.ID":"GO:0032604","Term":"granulocyte macrophage colony-stimulating factor production","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1710,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CD80,LILRA2"} {"GO.ID":"GO:0045176","Term":"apical protein localization","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1711,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"ATP8B1,CELSR1"} {"GO.ID":"GO:0020027","Term":"hemoglobin metabolic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1712,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"ALAS1,KLF4"} {"GO.ID":"GO:0006285","Term":"base-excision repair, AP site formation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1713,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"NEIL3,UNG"} {"GO.ID":"GO:0046598","Term":"positive regulation of viral entry into host cell","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1714,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CD74,HLA-DRB1"} {"GO.ID":"GO:0075294","Term":"positive regulation by symbiont of entry into host","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1715,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CD74,HLA-DRB1"} {"GO.ID":"GO:0097531","Term":"mast cell migration","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1716,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"KITLG,VEGFC"} {"GO.ID":"GO:0002921","Term":"negative regulation of humoral immune response","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1717,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CR1L,SERPING1"} {"GO.ID":"GO:0140042","Term":"lipid droplet formation","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1718,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"CDS1,RNF213"} {"GO.ID":"GO:0046655","Term":"folic acid metabolic process","Annotated":12,"Significant":2,"Expected":0.72,"Rank in p.value_classic":1719,"p.value_elim":0.16053,"p.value_classic":0.16118,"genes":"DHFR,MTHFD2"} {"GO.ID":"GO:0006911","Term":"phagocytosis, engulfment","Annotated":48,"Significant":5,"Expected":2.9,"Rank in p.value_classic":1723,"p.value_elim":0.16082,"p.value_classic":0.16202,"genes":"APPL2,C3,HAVCR1,STAP1,XKR6"} {"GO.ID":"GO:0006633","Term":"fatty acid biosynthetic process","Annotated":116,"Significant":10,"Expected":7.01,"Rank in p.value_classic":1726,"p.value_elim":0.16096,"p.value_classic":0.16277,"genes":"ACOT4,BRCA1,CD74,CEACAM1,CYP1A1,EDN1,LPL,LTC4S,PDK4,SLC45A3"} {"GO.ID":"GO:0044774","Term":"mitotic DNA integrity checkpoint signaling","Annotated":85,"Significant":11,"Expected":5.13,"Rank in p.value_classic":797,"p.value_elim":0.16215,"p.value_classic":0.01302,"genes":"BRCA1,CDC6,CDK1,CLSPN,DTL,EME1,GTSE1,MUC1,ORC1,PML,TICRR"} {"GO.ID":"GO:0030071","Term":"regulation of mitotic metaphase/anaphase transition","Annotated":87,"Significant":11,"Expected":5.25,"Rank in p.value_classic":820,"p.value_elim":0.16224,"p.value_classic":0.01534,"genes":"AURKB,BIRC5,BUB1B,CDC6,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0050851","Term":"antigen receptor-mediated signaling pathway","Annotated":147,"Significant":23,"Expected":8.88,"Rank in p.value_classic":315,"p.value_elim":0.16248,"p.value_classic":0.00002,"genes":"BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,CD28,CD38,CEACAM1,CTLA4,CYLD,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,ITK,LYN,PDE4B,RIPK2,STAP1,TNFRSF21,ZC3H12A"} {"GO.ID":"GO:0016053","Term":"organic acid biosynthetic process","Annotated":247,"Significant":19,"Expected":14.92,"Rank in p.value_classic":1727,"p.value_elim":0.16331,"p.value_classic":0.16594,"genes":"ACOT4,BRCA1,CD74,CEACAM1,CYP1A1,DHFR,DHRS9,DSE,EDN1,GGT5,GLUL,HSD3B7,IDO1,LPL,LTC4S,OSBPL6,PDK4,SERINC5,SLC45A3"} {"GO.ID":"GO:0048872","Term":"homeostasis of number of cells","Annotated":272,"Significant":30,"Expected":16.43,"Rank in p.value_classic":493,"p.value_elim":0.16373,"p.value_classic":0.00102,"genes":"AIM2,ALAS1,B2M,BCL2L11,BCL6,CD74,CSF1,CX3CR1,CYLD,EPAS1,FAS,GPR183,HCAR2,IL7,JAK2,JAK3,KITLG,LYN,MERTK,NCAPG2,NOD2,P2RX7,PDE4B,PMAIP1,POLB,SEPTIN4,SIT1,STAT1,TAL1,TNFSF13B"} {"GO.ID":"GO:0051090","Term":"regulation of DNA-binding transcription factor activity","Annotated":307,"Significant":23,"Expected":18.54,"Rank in p.value_classic":1731,"p.value_elim":0.16463,"p.value_classic":0.16757,"genes":"ACOD1,ADORA3,AGT,AIM2,CARD16,CD40,CYLD,EDA,EDN1,KLF4,NLRC5,NLRP12,NOD2,PARP10,PIM1,RHEBL1,RIPK2,TICAM2,TNFRSF11A,TNFSF18,TRIM22,TRIM31,ZC3H12A"} {"GO.ID":"GO:0051453","Term":"regulation of intracellular pH","Annotated":75,"Significant":7,"Expected":4.53,"Rank in p.value_classic":1729,"p.value_elim":0.16467,"p.value_classic":0.16616,"genes":"ATP6V0D2,LRRK2,OCA2,RAB20,SLAMF8,SLC11A1,SLC4A7"} {"GO.ID":"GO:0051851","Term":"modulation by host of symbiont process","Annotated":75,"Significant":7,"Expected":4.53,"Rank in p.value_classic":1730,"p.value_elim":0.16467,"p.value_classic":0.16616,"genes":"CCL5,CCL8,CX3CR1,IFI27,IGF2R,NOD2,ZC3H12A"} {"GO.ID":"GO:0030183","Term":"B cell differentiation","Annotated":117,"Significant":10,"Expected":7.07,"Rank in p.value_classic":1732,"p.value_elim":0.16719,"p.value_classic":0.16904,"genes":"BCL6,CYLD,DLL1,GPR183,IL4I1,IL7,JAK3,SLAMF8,TNFSF13B,VCAM1"} {"GO.ID":"GO:0043433","Term":"negative regulation of DNA-binding transcription factor activity","Annotated":117,"Significant":10,"Expected":7.07,"Rank in p.value_classic":1733,"p.value_elim":0.16719,"p.value_classic":0.16904,"genes":"ACOD1,ADORA3,AIM2,CYLD,KLF4,NLRC5,NLRP12,PARP10,PIM1,ZC3H12A"} {"GO.ID":"GO:2000514","Term":"regulation of CD4-positive, alpha-beta T cell activation","Annotated":66,"Significant":16,"Expected":3.99,"Rank in p.value_classic":234,"p.value_elim":0.16836,"p.value_classic":1.3e-06,"genes":"ASCL2,BCL6,CD274,CD28,CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,RIPK2,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:1901184","Term":"regulation of ERBB signaling pathway","Annotated":62,"Significant":6,"Expected":3.74,"Rank in p.value_classic":1734,"p.value_elim":0.16869,"p.value_classic":0.17007,"genes":"AGR2,AGT,CEACAM1,MMP9,MVP,RALB"} {"GO.ID":"GO:0001937","Term":"negative regulation of endothelial cell proliferation","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1735,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"GHRL,IL12A,MIR503,STAT1"} {"GO.ID":"GO:0070302","Term":"regulation of stress-activated protein kinase signaling cascade","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1736,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"FAS,LYN,NOD2,SCIMP"} {"GO.ID":"GO:0090102","Term":"cochlea development","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1737,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"CCNA2,MCM2,SOBP,TIFAB"} {"GO.ID":"GO:0030851","Term":"granulocyte differentiation","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1738,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"CEACAM1,LYN,TAL1,TESC"} {"GO.ID":"GO:0030574","Term":"collagen catabolic process","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1739,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"CTSL,CTSS,MMP25,MMP9"} {"GO.ID":"GO:0009620","Term":"response to fungus","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1740,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"CLEC6A,CX3CR1,SCIMP,ZBP1"} {"GO.ID":"GO:1904707","Term":"positive regulation of vascular associated smooth muscle cell proliferation","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1741,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"EDN1,JAK2,MMP9,NR4A3"} {"GO.ID":"GO:0040001","Term":"establishment of mitotic spindle localization","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1742,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"DYNLT1,MAD2L1,NDC80,NUSAP1"} {"GO.ID":"GO:0045840","Term":"positive regulation of mitotic nuclear division","Annotated":36,"Significant":4,"Expected":2.17,"Rank in p.value_classic":1743,"p.value_elim":0.16913,"p.value_classic":0.17021,"genes":"CD28,EDN1,LRP5,NUSAP1"} {"GO.ID":"GO:0043369","Term":"CD4-positive or CD8-positive, alpha-beta T cell lineage commitment","Annotated":25,"Significant":6,"Expected":1.51,"Rank in p.value_classic":602,"p.value_elim":0.16933,"p.value_classic":0.00313,"genes":"CTSL,CYLD,IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0051231","Term":"spindle elongation","Annotated":13,"Significant":5,"Expected":0.79,"Rank in p.value_classic":468,"p.value_elim":0.16938,"p.value_classic":0.00068,"genes":"AURKB,BIRC5,KIF11,KIF23,PRC1"} {"GO.ID":"GO:0098543","Term":"detection of other organism","Annotated":16,"Significant":5,"Expected":0.97,"Rank in p.value_classic":550,"p.value_elim":0.16942,"p.value_classic":0.00198,"genes":"CLEC6A,HLA-A,HLA-B,HLA-DRB1,NOD2"} {"GO.ID":"GO:0051767","Term":"nitric-oxide synthase biosynthetic process","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":581,"p.value_elim":0.16943,"p.value_classic":0.00267,"genes":"EDN1,JAK2,LRRK2,NOD2,STAT1"} {"GO.ID":"GO:0051769","Term":"regulation of nitric-oxide synthase biosynthetic process","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":582,"p.value_elim":0.16943,"p.value_classic":0.00267,"genes":"EDN1,JAK2,LRRK2,NOD2,STAT1"} {"GO.ID":"GO:1904018","Term":"positive regulation of vasculature development","Annotated":146,"Significant":12,"Expected":8.82,"Rank in p.value_classic":1744,"p.value_elim":0.17001,"p.value_classic":0.17209,"genes":"BRCA1,C3,CD40,CDH5,CX3CR1,CYSLTR1,DLL1,GHRL,KLF4,NRP1,VEGFC,ZC3H12A"} {"GO.ID":"GO:0061572","Term":"actin filament bundle organization","Annotated":146,"Significant":12,"Expected":8.82,"Rank in p.value_classic":1745,"p.value_elim":0.17001,"p.value_classic":0.17209,"genes":"FAM107A,FSCN1,ITGB5,MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:1902099","Term":"regulation of metaphase/anaphase transition of cell cycle","Annotated":88,"Significant":11,"Expected":5.31,"Rank in p.value_classic":826,"p.value_elim":0.17013,"p.value_classic":0.01661,"genes":"AURKB,BIRC5,BUB1B,CDC6,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0006935","Term":"chemotaxis","Annotated":373,"Significant":47,"Expected":22.53,"Rank in p.value_classic":232,"p.value_elim":0.17049,"p.value_classic":1.2e-06,"genes":"ADAM8,AMOT,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYSLTR1,EDN1,ENPP2,GPR183,HBEGF,HGF,HSD3B7,IL12A,KLRK1,LYN,MTUS1,NOD2,NRP1,P2RX4,PADI2,PDE4B,PROK2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,SUCNR1,TNFAIP6,TNFRSF11A,TYMP,VCAM1,VEGFC"} {"GO.ID":"GO:0042330","Term":"taxis","Annotated":373,"Significant":47,"Expected":22.53,"Rank in p.value_classic":233,"p.value_elim":0.17049,"p.value_classic":1.2e-06,"genes":"ADAM8,AMOT,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYSLTR1,EDN1,ENPP2,GPR183,HBEGF,HGF,HSD3B7,IL12A,KLRK1,LYN,MTUS1,NOD2,NRP1,P2RX4,PADI2,PDE4B,PROK2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,SUCNR1,TNFAIP6,TNFRSF11A,TYMP,VCAM1,VEGFC"} {"GO.ID":"GO:0030193","Term":"regulation of blood coagulation","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1746,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"CEACAM1,EDN1,ENPP4,SERPING1,THBD"} {"GO.ID":"GO:0030219","Term":"megakaryocyte differentiation","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1747,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"FAXDC2,MAF,SCIN,TAL1,TESC"} {"GO.ID":"GO:0000768","Term":"syncytium formation by plasma membrane fusion","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1748,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"ADAMTS15,CXCL10,CXCL9,SBNO2,SH3PXD2A"} {"GO.ID":"GO:0140253","Term":"cell-cell fusion","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1749,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"ADAMTS15,CXCL10,CXCL9,SBNO2,SH3PXD2A"} {"GO.ID":"GO:0071384","Term":"cellular response to corticosteroid stimulus","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1750,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"BCL2L11,EDN1,FAM107A,JAK2,SSTR2"} {"GO.ID":"GO:0001523","Term":"retinoid metabolic process","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1751,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"GO.ID":"GO:0035773","Term":"insulin secretion involved in cellular response to glucose stimulus","Annotated":49,"Significant":5,"Expected":2.96,"Rank in p.value_classic":1752,"p.value_elim":0.17086,"p.value_classic":0.17211,"genes":"GHRL,HLA-DRB1,LRP5,SIDT2,SRI"} {"GO.ID":"GO:0052372","Term":"modulation by symbiont of entry into host","Annotated":43,"Significant":9,"Expected":2.6,"Rank in p.value_classic":484,"p.value_elim":0.17092,"p.value_classic":0.0009,"genes":"CD74,CIITA,FCN1,HLA-DRB1,IFITM1,IFITM2,IFITM3,TRIM22,TRIM31"} {"GO.ID":"GO:0045165","Term":"cell fate commitment","Annotated":198,"Significant":19,"Expected":11.96,"Rank in p.value_classic":976,"p.value_elim":0.17121,"p.value_classic":0.03072,"genes":"CTSL,CYLD,DLL1,EDN1,EPAS1,EPOP,IL12RB1,IL7,IRF4,KLF4,NRP1,OLIG1,ONECUT2,PML,SLAMF6,SLAMF8,SOX17,TAL1,TBX21"} {"GO.ID":"GO:0001568","Term":"blood vessel development","Annotated":610,"Significant":49,"Expected":36.84,"Rank in p.value_classic":911,"p.value_elim":0.17143,"p.value_classic":0.02459,"genes":"ADAM8,AMOT,ANTXR1,BRCA1,C3,CD40,CDH5,CEACAM1,COMP,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,EGR2,EPAS1,EPHB3,GHRL,GLUL,HLA-G,IL12A,KLF4,LRP5,MIR503,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PML,PRKX,PROK2,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,STAT1,TAL1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0019058","Term":"viral life cycle","Annotated":282,"Significant":44,"Expected":17.03,"Rank in p.value_classic":142,"p.value_elim":0.17208,"p.value_classic":5.4e-09,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CCL8,CD28,CD74,CD80,CDK1,CHMP4C,CIITA,CTSL,CXADR,DYNLT1,FCN1,GBP7,HAVCR1,HLA-DRB1,ICAM1,IFI27,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,ITGB5,LAMP3,NRP1,OAS2,OAS3,PLSCR1,RSAD2,SLAMF1,TNFRSF14,TOP2A,TPCN1,TRIM22,TRIM31,TYRO3,USP6NL,WWP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0016239","Term":"positive regulation of macroautophagy","Annotated":76,"Significant":7,"Expected":4.59,"Rank in p.value_classic":1762,"p.value_elim":0.17264,"p.value_classic":0.17418,"genes":"CALCOCO2,NOD2,OPTN,RALB,RIPK2,RUFY4,SESN3"} {"GO.ID":"GO:0098901","Term":"regulation of cardiac muscle cell action potential","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1753,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"ANK2,CAMK2D,CXADR"} {"GO.ID":"GO:0080111","Term":"DNA demethylation","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1754,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0150146","Term":"cell junction disassembly","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1755,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"C1QB,C3,CX3CR1"} {"GO.ID":"GO:0002313","Term":"mature B cell differentiation involved in immune response","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1756,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"BCL6,DLL1,GPR183"} {"GO.ID":"GO:0043171","Term":"peptide catabolic process","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1757,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"CHAC1,ERAP2,GGT5"} {"GO.ID":"GO:0044827","Term":"modulation by host of viral genome replication","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1758,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"CCL8,IFI27,ZC3H12A"} {"GO.ID":"GO:0010955","Term":"negative regulation of protein processing","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1759,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"CARD16,CHAC1,LRRK2"} {"GO.ID":"GO:1903318","Term":"negative regulation of protein maturation","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1760,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"CARD16,CHAC1,LRRK2"} {"GO.ID":"GO:0001556","Term":"oocyte maturation","Annotated":24,"Significant":3,"Expected":1.45,"Rank in p.value_classic":1761,"p.value_elim":0.17313,"p.value_classic":0.17405,"genes":"DAZL,DMC1,EDN1"} {"GO.ID":"GO:0002244","Term":"hematopoietic progenitor cell differentiation","Annotated":118,"Significant":10,"Expected":7.13,"Rank in p.value_classic":1763,"p.value_elim":0.17352,"p.value_classic":0.17543,"genes":"ANLN,ESCO2,KITLG,LYN,OSM,PLEK,SSBP3,TAL1,TIFAB,TOP2A"} {"GO.ID":"GO:0030316","Term":"osteoclast differentiation","Annotated":90,"Significant":8,"Expected":5.44,"Rank in p.value_classic":1764,"p.value_elim":0.17425,"p.value_classic":0.17593,"genes":"CSF1,GPR183,LILRB3,SBNO2,SH3PXD2A,SNX10,TNFAIP6,TNFRSF11A"} {"GO.ID":"GO:1901653","Term":"cellular response to peptide","Annotated":301,"Significant":26,"Expected":18.18,"Rank in p.value_classic":1073,"p.value_elim":0.17506,"p.value_classic":0.04184,"genes":"AGT,APPL2,CASP4,CCNA2,CDC6,CEACAM1,CRHBP,EDN1,GHRL,ICAM1,JAK2,JAK3,KLF4,LYN,NOD2,NR4A3,PDE3B,PDK4,PID1,PNPLA3,PXN,RIPK2,SESN3,SOCS1,STAT1,VCAM1"} {"GO.ID":"GO:0050767","Term":"regulation of neurogenesis","Annotated":325,"Significant":24,"Expected":19.63,"Rank in p.value_classic":1766,"p.value_elim":0.17579,"p.value_classic":0.17894,"genes":"APPL2,ASCL2,B2M,BHLHE41,CX3CR1,CYSLTR1,DAB1,DLL1,DYNLT1,EGR2,FSTL4,HAPLN3,LTA,LYN,NRP1,PLXNA2,RAPGEF2,S100A10,SEMA6B,TGM2,VCAN,VEGFC,WDR62,XRCC2"} {"GO.ID":"GO:0040008","Term":"regulation of growth","Annotated":493,"Significant":35,"Expected":29.77,"Rank in p.value_classic":1767,"p.value_elim":0.17602,"p.value_classic":0.1799,"genes":"AGR2,AGT,BCL2L11,BCL6,BRCA1,CAMK2D,CD38,CDK1,CDKN2C,CEACAM1,CISH,COLQ,CSF1,DAB2,DLL1,EDN1,FAM107A,FSTL4,GHRL,HBEGF,IL7,JADE2,KIF26A,MT2A,NPR1,NRCAM,NRP1,PIM1,PML,SELENOP,SEMA6B,SGPL1,SOX17,SPTBN4,SYT1"} {"GO.ID":"GO:0016310","Term":"phosphorylation","Annotated":1305,"Significant":102,"Expected":78.82,"Rank in p.value_classic":621,"p.value_elim":0.17741,"p.value_classic":0.00354,"genes":"AATK,AGT,AK1,ATP13A2,AURKB,BANK1,BIRC5,BUB1B,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CIITA,CLEC6A,CLSPN,CMPK2,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,EDN1,ENPP2,EPHB3,FAM20A,FAS,FAXDC2,GK,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JAK2,JAK3,KITLG,LIMK2,LMTK2,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,NOD2,NRK,NRP1,OSM,P2RX7,PARP14,PARP9,PDK4,PID1,PIM1,PKIB,PKMYT1,PPM1E,PRKX,RALB,RAPGEF2,RIPK2,SLAMF8,SLC11A1,SOCS1,SPTBN4,STAP1,STAT2,TK1,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC,VRK2,WARS1,WEE1,ZC3H12A"} {"GO.ID":"GO:0006508","Term":"proteolysis","Annotated":1295,"Significant":86,"Expected":78.21,"Rank in p.value_classic":1823,"p.value_elim":0.17791,"p.value_classic":0.18443,"genes":"ADAM8,ADAMTS15,ADGB,AIM2,ASB2,ATP13A2,C1R,C1RL,C1S,C2,CARD16,CASP4,CASP7,CCNF,CFB,CFH,CHAC1,CHMP4C,CNDP2,COMP,CTRL,CTSL,CTSO,CTSS,CYLD,DAB2,DERL3,DNPEP,DTL,DTX3L,ECEL1,ERAP2,FAM111B,FAS,FBXO6,FCN1,FEM1C,GGT5,GRAMD4,GSAP,HTRA1,IFI27,JAK2,KLF4,LACTB,LAMP3,LAP3,LRRK2,LYN,MEFV,MMP25,MMP9,NLRP12,NUB1,OTUD1,P2RX7,PGA3,PGA4,PGA5,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RIPK2,RNF19B,RNF213,S100A10,SERPING1,STAMBPL1,TANK,TBX21,TGM2,THBD,TNFSF10,TRABD2A,TRIM31,TSPAN15,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0007169","Term":"transmembrane receptor protein tyrosine kinase signaling pathway","Annotated":516,"Significant":40,"Expected":31.16,"Rank in p.value_classic":1192,"p.value_elim":0.17792,"p.value_classic":0.06185,"genes":"AGR2,AGT,CD7,CEACAM1,CSF1,DLL1,EPHB3,FSTL4,GAREM1,GFRA2,GHRL,HBEGF,HGF,IGF2R,IL12A,IL31RA,JAK2,JAK3,LYN,MERTK,MIR503,MMP9,MTSS1,MVP,NR4A3,NRP1,PDK4,PID1,PXN,RALB,RAPGEF2,REPS2,SESN3,SGPL1,SHCBP1,SOCS1,STAP1,STMN1,TYRO3,VEGFC"} {"GO.ID":"GO:0035295","Term":"tube development","Annotated":911,"Significant":68,"Expected":55.02,"Rank in p.value_classic":1048,"p.value_elim":0.17811,"p.value_classic":0.03895,"genes":"ADAM8,AGR2,AGT,AMOT,ASB2,BCL2L11,BRCA1,C3,CD40,CDH5,CEACAM1,CELSR1,CHRD,COMP,CSF1,CTNS,CX3CR1,CXCL10,CXCR3,CYP1A1,CYSLTR1,DLL1,DNAAF1,E2F2,E2F8,EDA,EDN1,EPAS1,EPHB3,GHRL,GLUL,HESX1,HLA-G,HSD11B1,IFT122,IL12A,KLF4,LRP5,MICAL2,MIR503,MTSS1,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PLXNA2,PML,PRKX,PROK2,RAPGEF2,RNF213,RXFP1,S1PR1,SAT1,SGPL1,SOX17,SSBP3,STAT1,TAL1,TGM2,THBS2,TNFAIP2,TYMP,TYMS,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0042180","Term":"cellular ketone metabolic process","Annotated":162,"Significant":13,"Expected":9.78,"Rank in p.value_classic":1768,"p.value_elim":0.17854,"p.value_classic":0.1808,"genes":"AIFM2,APPL2,BRCA1,CBR3,CD74,CEACAM1,DAB2,DHRS9,IDO1,IDO2,NR4A3,PDK4,SLC45A3"} {"GO.ID":"GO:0051250","Term":"negative regulation of lymphocyte activation","Annotated":129,"Significant":29,"Expected":7.79,"Rank in p.value_classic":119,"p.value_elim":0.17889,"p.value_classic":5e-10,"genes":"ASCL2,BANK1,BCL6,BTN2A2,CD274,CD74,CD80,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,IRF1,JAK3,LAG3,LYN,MERTK,PARP3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,TYRO3,ZC3H12A"} {"GO.ID":"GO:0009791","Term":"post-embryonic development","Annotated":77,"Significant":7,"Expected":4.65,"Rank in p.value_classic":1773,"p.value_elim":0.18078,"p.value_classic":0.18237,"genes":"ATF5,BCL2L11,IGF2R,JAK2,KLF4,SELENOP,SGPL1"} {"GO.ID":"GO:0120162","Term":"positive regulation of cold-induced thermogenesis","Annotated":77,"Significant":7,"Expected":4.65,"Rank in p.value_classic":1774,"p.value_elim":0.18078,"p.value_classic":0.18237,"genes":"ACSL1,APPL2,EPAS1,G0S2,GHRL,IRF4,JAK2"} {"GO.ID":"GO:0099565","Term":"chemical synaptic transmission, postsynaptic","Annotated":77,"Significant":7,"Expected":4.65,"Rank in p.value_classic":1775,"p.value_elim":0.18078,"p.value_classic":0.18237,"genes":"GHRL,INSYN2A,LRRK2,P2RX4,P2RX7,STX1A,SYNE1"} {"GO.ID":"GO:0001947","Term":"heart looping","Annotated":50,"Significant":5,"Expected":3.02,"Rank in p.value_classic":1776,"p.value_elim":0.18113,"p.value_classic":0.18243,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0043124","Term":"negative regulation of canonical NF-kappaB signal transduction","Annotated":50,"Significant":5,"Expected":3.02,"Rank in p.value_classic":1777,"p.value_elim":0.18113,"p.value_classic":0.18243,"genes":"NLRP12,OPTN,STAT1,TANK,ZC3H12A"} {"GO.ID":"GO:0051452","Term":"intracellular pH reduction","Annotated":50,"Significant":5,"Expected":3.02,"Rank in p.value_classic":1778,"p.value_elim":0.18113,"p.value_classic":0.18243,"genes":"ATP6V0D2,RAB20,SLAMF8,SLC11A1,SLC4A7"} {"GO.ID":"GO:0014075","Term":"response to amine","Annotated":37,"Significant":4,"Expected":2.23,"Rank in p.value_classic":1769,"p.value_elim":0.18123,"p.value_classic":0.18237,"genes":"ASIC1,CDK1,EDN1,JAK2"} {"GO.ID":"GO:0060443","Term":"mammary gland morphogenesis","Annotated":37,"Significant":4,"Expected":2.23,"Rank in p.value_classic":1770,"p.value_elim":0.18123,"p.value_classic":0.18237,"genes":"CSF1,LRP5,PML,RXFP1"} {"GO.ID":"GO:0072528","Term":"pyrimidine-containing compound biosynthetic process","Annotated":37,"Significant":4,"Expected":2.23,"Rank in p.value_classic":1771,"p.value_elim":0.18123,"p.value_classic":0.18237,"genes":"CMPK2,SLC4A7,TK1,TYMS"} {"GO.ID":"GO:0046622","Term":"positive regulation of organ growth","Annotated":37,"Significant":4,"Expected":2.23,"Rank in p.value_classic":1772,"p.value_elim":0.18123,"p.value_classic":0.18237,"genes":"CDK1,EDN1,IL7,PIM1"} {"GO.ID":"GO:0060048","Term":"cardiac muscle contraction","Annotated":105,"Significant":9,"Expected":6.34,"Rank in p.value_classic":1779,"p.value_elim":0.1813,"p.value_classic":0.18314,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SRI,ZC3H12A"} {"GO.ID":"GO:1902105","Term":"regulation of leukocyte differentiation","Annotated":275,"Significant":44,"Expected":16.61,"Rank in p.value_classic":134,"p.value_elim":0.18165,"p.value_classic":2.5e-09,"genes":"ADAM8,ASCL2,BCL6,BTN2A2,CD101,CD28,CD74,CD80,CD83,CEACAM1,CSF1,CTLA4,CYLD,FGL2,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,IRF7,JAK3,KITLG,LAG3,LILRB3,LYN,RIPK2,SLAMF8,SOCS1,TAL1,TBX21,TESC,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0002377","Term":"immunoglobulin production","Annotated":91,"Significant":8,"Expected":5.5,"Rank in p.value_classic":1821,"p.value_elim":0.18172,"p.value_classic":0.18345,"genes":"BCL6,CD28,EXO1,HLA-E,PARP3,POLB,TBX21,UNG"} {"GO.ID":"GO:0110020","Term":"regulation of actomyosin structure organization","Annotated":91,"Significant":8,"Expected":5.5,"Rank in p.value_classic":1822,"p.value_elim":0.18172,"p.value_classic":0.18345,"genes":"EDN1,NRP1,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0014048","Term":"regulation of glutamate secretion","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1780,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"DTNBP1,P2RX7"} {"GO.ID":"GO:2001212","Term":"regulation of vasculogenesis","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1781,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CEACAM1,RAPGEF2"} {"GO.ID":"GO:0044070","Term":"regulation of monoatomic anion transport","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1782,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ABCB1,ATP8B1"} {"GO.ID":"GO:0070341","Term":"fat cell proliferation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1783,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"E2F1,PID1"} {"GO.ID":"GO:0120305","Term":"regulation of pigmentation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1784,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"BCL2L11,KITLG"} {"GO.ID":"GO:0090235","Term":"regulation of metaphase plate congression","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1785,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"AURKB,BIRC5"} {"GO.ID":"GO:0060263","Term":"regulation of respiratory burst","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1786,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"NCF1,SLAMF8"} {"GO.ID":"GO:0030852","Term":"regulation of granulocyte differentiation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1787,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CEACAM1,TESC"} {"GO.ID":"GO:0000712","Term":"resolution of meiotic recombination intermediates","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1788,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"EME1,TOP2A"} {"GO.ID":"GO:0070243","Term":"regulation of thymocyte apoptotic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1789,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ADAM8,JAK3"} {"GO.ID":"GO:0072074","Term":"kidney mesenchyme development","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1790,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"AMER1,STAT1"} {"GO.ID":"GO:0048070","Term":"regulation of developmental pigmentation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1791,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"BCL2L11,KITLG"} {"GO.ID":"GO:0032352","Term":"positive regulation of hormone metabolic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1792,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CTNS,DAB2"} {"GO.ID":"GO:1903019","Term":"negative regulation of glycoprotein metabolic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1793,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"HBEGF,JAK3"} {"GO.ID":"GO:1900103","Term":"positive regulation of endoplasmic reticulum unfolded protein response","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1794,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"AGR2,BCL2L11"} {"GO.ID":"GO:1900272","Term":"negative regulation of long-term synaptic potentiation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1795,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CX3CR1,FAM107A"} {"GO.ID":"GO:0044793","Term":"negative regulation by host of viral process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1796,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CCL8,ZC3H12A"} {"GO.ID":"GO:0006071","Term":"glycerol metabolic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1797,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"DGAT2,GK"} {"GO.ID":"GO:2000479","Term":"regulation of cAMP-dependent protein kinase activity","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1798,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"PKIB,RAPGEF2"} {"GO.ID":"GO:1901018","Term":"positive regulation of potassium ion transmembrane transporter activity","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1799,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ANK2,ATP1B2"} {"GO.ID":"GO:0031115","Term":"negative regulation of microtubule polymerization","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1800,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CDH5,STMN1"} {"GO.ID":"GO:0071371","Term":"cellular response to gonadotropin stimulus","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1801,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CCNA2,EDN1"} {"GO.ID":"GO:0072160","Term":"nephron tubule epithelial cell differentiation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1802,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"MTSS1,STAT1"} {"GO.ID":"GO:0032736","Term":"positive regulation of interleukin-13 production","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1803,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"HLA-E,IRF4"} {"GO.ID":"GO:0038203","Term":"TORC2 signaling","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1804,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"DEPTOR,SESN3"} {"GO.ID":"GO:0007190","Term":"activation of adenylate cyclase activity","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1805,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0033623","Term":"regulation of integrin activation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1806,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"PLEK,PTGER4"} {"GO.ID":"GO:0043649","Term":"dicarboxylic acid catabolic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1807,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ACOT4,GLUL"} {"GO.ID":"GO:0016264","Term":"gap junction assembly","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1808,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"AGT,GJD3"} {"GO.ID":"GO:0061760","Term":"antifungal innate immune response","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1809,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CLEC6A,CX3CR1"} {"GO.ID":"GO:0032688","Term":"negative regulation of interferon-beta production","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1810,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"NMI,RELB"} {"GO.ID":"GO:0021516","Term":"dorsal spinal cord development","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1811,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"MDGA1,TAL1"} {"GO.ID":"GO:0048520","Term":"positive regulation of behavior","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1812,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"GHRL,NR4A3"} {"GO.ID":"GO:0061577","Term":"calcium ion transmembrane transport via high voltage-gated calcium channel","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1813,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CAMK2D,PDE4B"} {"GO.ID":"GO:0051547","Term":"regulation of keratinocyte migration","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1814,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"HBEGF,MMP9"} {"GO.ID":"GO:0019370","Term":"leukotriene biosynthetic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1815,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"GGT5,LTC4S"} {"GO.ID":"GO:0035864","Term":"response to potassium ion","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1816,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CRHBP,KCNJ10"} {"GO.ID":"GO:0042983","Term":"amyloid precursor protein biosynthetic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1817,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"NECAB2,SOAT1"} {"GO.ID":"GO:0042984","Term":"regulation of amyloid precursor protein biosynthetic process","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1818,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"NECAB2,SOAT1"} {"GO.ID":"GO:0032908","Term":"regulation of transforming growth factor beta1 production","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1819,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0006590","Term":"thyroid hormone generation","Annotated":13,"Significant":2,"Expected":0.79,"Rank in p.value_classic":1820,"p.value_elim":0.18252,"p.value_classic":0.18324,"genes":"CTNS,SLC16A10"} {"GO.ID":"GO:0071675","Term":"regulation of mononuclear cell migration","Annotated":103,"Significant":14,"Expected":6.22,"Rank in p.value_classic":611,"p.value_elim":0.18261,"p.value_classic":0.00351,"genes":"ADAM8,ASCL2,CCL5,CCL7,CSF1,CX3CR1,CXCL10,IL12A,KLRK1,LYN,PADI2,SLAMF1,SLAMF8,TNFRSF14"} {"GO.ID":"GO:0051129","Term":"negative regulation of cellular component organization","Annotated":650,"Significant":48,"Expected":39.26,"Rank in p.value_classic":1306,"p.value_elim":0.18456,"p.value_classic":0.08473,"genes":"ANTXR1,AURKB,B2M,BIRC5,BRCA1,BUB1B,CCNF,CD300LF,CD38,CDH5,CENPF,CXCL10,DAB1,DAB2,DTNBP1,DYSF,FAM107A,FSTL4,HGF,HORMAD1,IL15RA,KREMEN1,LIMK2,LRRK2,MAD2L1,MEFV,NDC80,NECAB2,NRP1,NUF2,PLSCR1,PRRT2,PTGER4,RAPGEF2,RTN4RL1,S1PR1,SCIN,SEMA6B,SPC24,SPC25,SPTBN4,STAP1,STMN1,TMSB10,TOP2A,TRIM31,XRN1,ZWINT"} {"GO.ID":"GO:0065009","Term":"regulation of molecular function","Annotated":1652,"Significant":126,"Expected":99.77,"Rank in p.value_classic":587,"p.value_elim":0.18473,"p.value_classic":0.00284,"genes":"ABCB1,ACOD1,ADORA3,AGT,AIM2,ANK2,AOC3,ATP13A2,ATP1B2,AURKB,B2M,CAMK2D,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CD40,CD74,CDC25A,CDC6,CDKN2C,CDT1,CEACAM1,CHTF18,CLSPN,CRHBP,CSF1,CTSL,CTSS,CYLD,DAB2,DEPTOR,DHFR,DLGAP3,DSCC1,DTNBP1,DTX3L,E2F1,EDA,EDN1,EPHB3,FAS,FGD5,GCH1,GRAMD4,HJURP,HLA-DRB1,IFIT2,ITK,JAK2,KCNE5,KLF4,KLRK1,LAMP3,LRP5,LRRK2,LYN,MAD2L1,MEFV,MERTK,MMD,MMP9,MVP,NCF1,NLRC5,NLRP12,NOD2,NRP1,OAS2,OAS3,PARP10,PARP3,PARP9,PIM1,PKIB,PKMYT1,PLAAT4,PLEK,PLSCR1,PLXNA2,PMAIP1,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RHEBL1,RIPK2,RSU1,RXFP1,S100A10,SCN4B,SERINC5,SERPING1,SLAMF8,SLC11A1,SRI,STMN1,SYNGR3,TANK,TESC,TGM2,TICAM2,TNFRSF11A,TNFSF10,TNFSF18,TRDN,TRIM22,TRIM31,TYRO3,UHRF1,USP6NL,WARS1,XIRP1,ZC3H12A"} {"GO.ID":"GO:0001667","Term":"ameboidal-type cell migration","Annotated":373,"Significant":27,"Expected":22.53,"Rank in p.value_classic":1829,"p.value_elim":0.18492,"p.value_classic":0.18839,"genes":"AGT,AMOT,ANLN,APPL2,CD40,CDH5,CEACAM1,EDN1,ENPP2,GLIPR2,GLUL,HBEGF,KITLG,KLF4,LRP5,MIR503,MMP9,NRP1,P2RX4,PML,PRKX,PXN,SEMA6B,SGPL1,SOX17,VEGFC,ZC3H12A"} {"GO.ID":"GO:0002764","Term":"immune response-regulating signaling pathway","Annotated":417,"Significant":64,"Expected":25.18,"Rank in p.value_classic":81,"p.value_elim":0.18594,"p.value_classic":3.4e-12,"genes":"ACOD1,AIM2,APPL2,AURKB,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CD274,CD28,CD300LF,CD38,CD40,CEACAM1,CLEC6A,COLEC12,CTLA4,CTSS,CYLD,DDX60,FCN1,FYB1,GBP1,GBP2,GBP5,GRAMD4,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,IFI35,IFIH1,IRF1,IRF4,IRF7,ITK,KLRK1,LILRA2,LYN,MEFV,NMI,NOD2,NR4A3,OAS3,PDE4B,PLPP4,PLSCR1,RIPK2,RSAD2,SCIMP,STAP1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF21,TRIM31,TYRO3,ZC3H12A"} {"GO.ID":"GO:0051057","Term":"positive regulation of small GTPase mediated signal transduction","Annotated":64,"Significant":6,"Expected":3.87,"Rank in p.value_classic":1825,"p.value_elim":0.1868,"p.value_classic":0.18829,"genes":"CSF1,F2RL3,KITLG,MCF2L,RASGRF1,TGM2"} {"GO.ID":"GO:0010657","Term":"muscle cell apoptotic process","Annotated":64,"Significant":6,"Expected":3.87,"Rank in p.value_classic":1826,"p.value_elim":0.1868,"p.value_classic":0.18829,"genes":"CAMK2D,EDN1,GCH1,IL12A,JAK2,ZC3H12A"} {"GO.ID":"GO:0086001","Term":"cardiac muscle cell action potential","Annotated":64,"Significant":6,"Expected":3.87,"Rank in p.value_classic":1827,"p.value_elim":0.1868,"p.value_classic":0.18829,"genes":"ANK2,CAMK2D,CXADR,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0010324","Term":"membrane invagination","Annotated":64,"Significant":6,"Expected":3.87,"Rank in p.value_classic":1828,"p.value_elim":0.1868,"p.value_classic":0.18829,"genes":"APPL2,AURKB,C3,HAVCR1,STAP1,XKR6"} {"GO.ID":"GO:1901342","Term":"regulation of vasculature development","Annotated":248,"Significant":25,"Expected":14.98,"Rank in p.value_classic":725,"p.value_elim":0.18709,"p.value_classic":0.00824,"genes":"AMOT,BRCA1,C3,CD40,CDH5,CEACAM1,CX3CR1,CXCL10,CYSLTR1,DLL1,E2F2,GHRL,GLUL,HLA-G,KLF4,MIR503,NPR1,NRP1,PDE3B,PML,STAT1,THBS2,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0009267","Term":"cellular response to starvation","Annotated":149,"Significant":12,"Expected":9,"Rank in p.value_classic":1842,"p.value_elim":0.18736,"p.value_classic":0.18959,"genes":"ATF3,CASTOR1,FAS,GLUL,LRRK2,MAP1LC3C,PDK4,PMAIP1,RALB,SESN3,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0071417","Term":"cellular response to organonitrogen compound","Annotated":488,"Significant":38,"Expected":29.47,"Rank in p.value_classic":1205,"p.value_elim":0.1874,"p.value_classic":0.06393,"genes":"AGT,APPL2,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CDC6,CEACAM1,CRHBP,DTNBP1,EDN1,GHRL,GNG2,ICAM1,JAK2,JAK3,KLF4,LRRK2,LYN,NOD2,NR4A3,P2RX4,P2RX7,PDE3B,PDK4,PID1,PNPLA3,PXN,RAPGEF2,RIPK2,SESN3,SOCS1,STAMBPL1,STAT1,TGM2,VCAM1,XRN1"} {"GO.ID":"GO:1903305","Term":"regulation of regulated secretory pathway","Annotated":106,"Significant":9,"Expected":6.4,"Rank in p.value_classic":1843,"p.value_elim":0.18833,"p.value_classic":0.19023,"genes":"CEACAM1,DTNBP1,HLA-F,LRRK2,LYN,STX1A,SV2B,SYT1,SYT6"} {"GO.ID":"GO:0009264","Term":"deoxyribonucleotide catabolic process","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1832,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"DPYS,TYMP,UNG"} {"GO.ID":"GO:0010737","Term":"protein kinase A signaling","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1833,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"AKAP7,EDN1,LRRK2"} {"GO.ID":"GO:0006929","Term":"substrate-dependent cell migration","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1834,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"ADAM8,NRP1,VEGFC"} {"GO.ID":"GO:1903077","Term":"negative regulation of protein localization to plasma membrane","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1835,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"DAB2,GBP1,PID1"} {"GO.ID":"GO:0032469","Term":"endoplasmic reticulum calcium ion homeostasis","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1836,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"CAMK2D,PML,TGM2"} {"GO.ID":"GO:1902042","Term":"negative regulation of extrinsic apoptotic signaling pathway via death domain receptors","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1837,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"BRCA1,HGF,ICAM1"} {"GO.ID":"GO:0060603","Term":"mammary gland duct morphogenesis","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1838,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"CSF1,LRP5,PML"} {"GO.ID":"GO:0055023","Term":"positive regulation of cardiac muscle tissue growth","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1839,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"CDK1,EDN1,PIM1"} {"GO.ID":"GO:0046386","Term":"deoxyribose phosphate catabolic process","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1840,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"DPYS,TYMP,UNG"} {"GO.ID":"GO:0002862","Term":"negative regulation of inflammatory response to antigenic stimulus","Annotated":25,"Significant":3,"Expected":1.51,"Rank in p.value_classic":1841,"p.value_elim":0.18852,"p.value_classic":0.18949,"genes":"HLA-DRB1,LYN,NOD2"} {"GO.ID":"GO:0043122","Term":"regulation of canonical NF-kappaB signal transduction","Annotated":258,"Significant":27,"Expected":15.58,"Rank in p.value_classic":625,"p.value_elim":0.18886,"p.value_classic":0.00375,"genes":"APOL3,CARD16,CD40,CD74,CLEC6A,CX3CR1,EDA,EDN1,GBP7,HLA-DRB1,IFIT5,LITAF,NLRP12,NOD2,OPTN,RIPK2,S100A13,SECTM1,SLC20A1,STAT1,TANK,TICAM2,TIFA,TNFSF10,TRIM22,UBD,ZC3H12A"} {"GO.ID":"GO:0032465","Term":"regulation of cytokinesis","Annotated":78,"Significant":7,"Expected":4.71,"Rank in p.value_classic":1844,"p.value_elim":0.18907,"p.value_classic":0.19071,"genes":"AURKB,BIRC5,CDC6,CHMP4C,E2F8,KIF23,PRC1"} {"GO.ID":"GO:0030641","Term":"regulation of cellular pH","Annotated":78,"Significant":7,"Expected":4.71,"Rank in p.value_classic":1845,"p.value_elim":0.18907,"p.value_classic":0.19071,"genes":"ATP6V0D2,LRRK2,OCA2,RAB20,SLAMF8,SLC11A1,SLC4A7"} {"GO.ID":"GO:0000041","Term":"transition metal ion transport","Annotated":78,"Significant":7,"Expected":4.71,"Rank in p.value_classic":1846,"p.value_elim":0.18907,"p.value_classic":0.19071,"genes":"B2M,FLVCR2,LMTK2,SLC11A1,SLC25A28,SLC31A2,STEAP4"} {"GO.ID":"GO:0010038","Term":"response to metal ion","Annotated":283,"Significant":21,"Expected":17.09,"Rank in p.value_classic":1849,"p.value_elim":0.1891,"p.value_classic":0.19217,"genes":"ATP13A2,B2M,CAMK2D,CDK1,CRHBP,CYP1A1,EDN1,HESX1,KCNJ10,LRRK2,MMP9,MT2A,NCF1,P2RX4,P2RX7,PLSCR1,SLC11A1,SUCNR1,SYT1,SYT6,VCAM1"} {"GO.ID":"GO:0002694","Term":"regulation of leukocyte activation","Annotated":480,"Significant":77,"Expected":28.99,"Rank in p.value_classic":45,"p.value_elim":0.18924,"p.value_classic":1.6e-15,"genes":"ADAM8,ASCL2,B2M,BANK1,BCL6,BTN2A2,CCL5,CD274,CD28,CD300LF,CD38,CD74,CD80,CD83,CTLA4,CYLD,FGL1,FGL2,GPR183,HAVCR1,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LRRK2,LYN,MERTK,NOD2,NR4A3,PARP3,PDCD1LG2,PLSCR1,RIPK2,SIT1,SLAMF1,SLAMF8,SOCS1,STAP1,TBX21,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,VCAM1,ZC3H12A"} {"GO.ID":"GO:0097237","Term":"cellular response to toxic substance","Annotated":92,"Significant":8,"Expected":5.56,"Rank in p.value_classic":1847,"p.value_elim":0.18933,"p.value_classic":0.19111,"genes":"ABCG2,AIFM2,DHFR,GCH1,GSTK1,LTC4S,PIM1,SLC11A1"} {"GO.ID":"GO:0038066","Term":"p38MAPK cascade","Annotated":51,"Significant":5,"Expected":3.08,"Rank in p.value_classic":1850,"p.value_elim":0.19162,"p.value_classic":0.19298,"genes":"CYLD,GADD45B,HGF,NCF1,ZC3H12A"} {"GO.ID":"GO:0061371","Term":"determination of heart left/right asymmetry","Annotated":51,"Significant":5,"Expected":3.08,"Rank in p.value_classic":1851,"p.value_elim":0.19162,"p.value_classic":0.19298,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0048856","Term":"anatomical structure development","Annotated":4482,"Significant":316,"Expected":270.69,"Rank in p.value_classic":414,"p.value_elim":0.19332,"p.value_classic":0.0003,"genes":"AATK,ACOD1,ADAM8,ADAMTS15,ADGB,AGR2,AGT,AIM2,ALAS1,AMER1,AMOT,ANK2,ANKH,ANLN,ANTXR1,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP1B2,ATP8B1,AURKB,B2M,BATF2,BATF3,BCL2L11,BCL6,BHLHE41,BRCA1,BTN2A2,C1QTNF5,C21orf91,C3,C3orf70,CASP7,CASZ1,CCL13,CCL7,CCNA2,CCNF,CD101,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CDKN2C,CEACAM1,CELSR1,CENPF,CENPU,CHAC1,CHMP4C,CHRD,CIBAR1,COL9A2,COLQ,COMP,CSF1,CTLA4,CTNS,CTSL,CX3CR1,CXADR,CXCL10,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DNAAF1,DTNBP1,DYNLT1,E2F1,E2F2,E2F8,EDA,EDN1,EGR2,ENPP2,EPAS1,EPHB3,EPOP,ESCO2,ETV7,EXO1,FAM20A,FAXDC2,FGD5,FGL1,FGL2,FLT3LG,FMNL2,FSTL4,GABRA3,GCNT3,GFRA2,GHRL,GINS1,GLDN,GLIPR2,GLUL,GPR183,GRIN3A,GSTK1,HAPLN3,HBEGF,HELLS,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-E,HLA-G,HORMAD1,HSD11B1,HTRA1,ICAM1,IDO1,IFT122,IGF2R,IL12A,IL12RB1,IL15,IL15RA,IL1RN,IL27,IL31RA,IL4I1,IL7,INA,IQGAP3,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KREMEN1,LAG3,LAMB3,LBH,LGI2,LILRB3,LIMK2,LPL,LRATD1,LRP5,LRRK2,LTA,LYN,LYVE1,MAF,MAFF,MARCKSL1,MARVELD2,MCM2,MDGA1,MERTK,MICAL2,MIR503,MMD,MMP25,MMP9,MPZL2,MTSS1,MYO7B,MYOZ2,NCAPG2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRN1,NRP1,NYAP2,OAS2,OCA2,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PADI2,PAQR5,PAQR8,PARP3,PCDH12,PCDHGC3,PDCD1,PDE3B,PID1,PIM1,PKD1L3,PLAAT3,PLAAT4,PLCD3,PLEK,PLPP4,PLXNA2,PML,POLB,PRKX,PROK2,PSMB10,PTGER4,PTPRU,RAPGEF2,RASGRF1,RELB,RHOBTB3,RIPK2,RNF213,RRM2,RSAD2,RTN4RL1,RXFP1,S100A10,S1PR1,SAT1,SBNO2,SCARF1,SCIN,SCO2,SDC2,SECTM1,SELENOP,SEMA6B,SEPTIN4,SERINC5,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC20A1,SLC45A3,SLC4A7,SNX10,SOBP,SOCS1,SOX17,SPTBN4,SRI,SSBP3,SSTR2,STAP1,STAT1,STAT2,STMN1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TBX21,TESC,TGM2,THBS2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TNFSF8,TOP2A,TRABD2A,TYMP,TYMS,TYRO3,UBD,UNG,VAMP5,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,WWP1,XKR6,XRCC2,XYLT1,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0000731","Term":"DNA synthesis involved in DNA repair","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1853,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"DTL,PARP10,PCLAF,POLE2"} {"GO.ID":"GO:0050856","Term":"regulation of T cell receptor signaling pathway","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1854,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"BTN2A2,CEACAM1,CYLD,GBP1"} {"GO.ID":"GO:0050829","Term":"defense response to Gram-negative bacterium","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1855,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"GSDMD,OPTN,SLC11A1,TNFRSF14"} {"GO.ID":"GO:1903351","Term":"cellular response to dopamine","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1856,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"DTNBP1,GNG2,LRRK2,TGM2"} {"GO.ID":"GO:0046456","Term":"icosanoid biosynthetic process","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1857,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"CD74,EDN1,GGT5,LTC4S"} {"GO.ID":"GO:0010463","Term":"mesenchymal cell proliferation","Annotated":38,"Significant":4,"Expected":2.3,"Rank in p.value_classic":1858,"p.value_elim":0.19361,"p.value_classic":0.19481,"genes":"CHRD,LRP5,STAT1,SYNE1"} {"GO.ID":"GO:1903532","Term":"positive regulation of secretion by cell","Annotated":221,"Significant":20,"Expected":13.35,"Rank in p.value_classic":1082,"p.value_elim":0.19405,"p.value_classic":0.04596,"genes":"ADAM8,ATP13A2,CADPS2,CD38,DAB2,DTNBP1,EDN1,GHRL,HCAR2,HLA-DRB1,HLA-F,JAK2,P2RX4,P2RX7,S100A10,SRI,STX1A,SYT1,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0007091","Term":"metaphase/anaphase transition of mitotic cell cycle","Annotated":91,"Significant":11,"Expected":5.5,"Rank in p.value_classic":886,"p.value_elim":0.19475,"p.value_classic":0.02088,"genes":"AURKB,BIRC5,BUB1B,CDC6,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0045921","Term":"positive regulation of exocytosis","Annotated":65,"Significant":6,"Expected":3.93,"Rank in p.value_classic":1860,"p.value_elim":0.19613,"p.value_classic":0.19767,"genes":"ATP13A2,CADPS2,HLA-F,S100A10,STX1A,SYT1"} {"GO.ID":"GO:0060429","Term":"epithelium development","Annotated":891,"Significant":60,"Expected":53.81,"Rank in p.value_classic":1863,"p.value_elim":0.19635,"p.value_classic":0.202,"genes":"AGR2,AGT,ASB2,C3,CDH5,CDK1,CEACAM1,CELSR1,CHRD,CSF1,CTNS,CXCL10,CYP1A1,DAB2,DHRS9,DLL1,DNAAF1,E2F8,EDA,EDN1,EPAS1,GSTK1,HBEGF,HESX1,HGF,ICAM1,IFT122,IL31RA,IQGAP3,ITGB5,JAK2,KLF4,LBH,LRP5,MAF,MAFF,MARVELD2,MICAL2,MMP9,MTSS1,NRP1,ONECUT2,OVOL1,PLAAT3,PLAAT4,PLXNA2,PML,PRKX,RAPGEF2,S1PR1,SIDT2,SLC4A7,SOX17,SSBP3,STAT1,STMN1,TGM2,TYMS,VEGFC,XRCC2"} {"GO.ID":"GO:0046634","Term":"regulation of alpha-beta T cell activation","Annotated":95,"Significant":22,"Expected":5.74,"Rank in p.value_classic":164,"p.value_elim":0.19654,"p.value_classic":3.5e-08,"genes":"ASCL2,BCL6,CD274,CD28,CD80,CD83,HLA-A,HLA-DRA,HLA-DRB1,HLA-E,IL12A,IL12RB1,IL27,IRF1,IRF4,JAK2,JAK3,RIPK2,SOCS1,TBX21,TNFRSF14,ZC3H12A"} {"GO.ID":"GO:0009607","Term":"response to biotic stimulus","Annotated":1175,"Significant":189,"Expected":70.96,"Rank in p.value_classic":5,"p.value_elim":0.19677,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,B2M,BANK1,BATF2,BATF3,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD40,CD74,CD80,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,CMPK2,COLEC12,CSF1,CSF2RB,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,DDX60,DTX3L,EDN1,EME1,FAM20A,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GRAMD4,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL18BP,IL27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLF4,KLRK1,LAG3,LILRA2,LITAF,LPL,LTA,LYN,MCOLN2,MEFV,MMP9,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,P2RX7,PARP14,PARP9,PDCD1LG2,PDE4B,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PML,PPM1E,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SBNO2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,STAT1,STAT2,STMN1,TANK,TAP2,TBX21,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM255A,TNFRSF11A,TNFRSF14,TNFSF8,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,VCAM1,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0051384","Term":"response to glucocorticoid","Annotated":93,"Significant":8,"Expected":5.62,"Rank in p.value_classic":1861,"p.value_elim":0.19707,"p.value_classic":0.1989,"genes":"BCL2L11,EDN1,FAM107A,IL1RN,JAK2,PTPRU,SSTR2,TYMS"} {"GO.ID":"GO:0002711","Term":"positive regulation of T cell mediated immunity","Annotated":59,"Significant":18,"Expected":3.56,"Rank in p.value_classic":143,"p.value_elim":0.19751,"p.value_classic":5.8e-09,"genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,P2RX7,RSAD2,SLAMF1,TAP2,TBX21"} {"GO.ID":"GO:0010035","Term":"response to inorganic substance","Annotated":423,"Significant":30,"Expected":25.55,"Rank in p.value_classic":1864,"p.value_elim":0.19943,"p.value_classic":0.2033,"genes":"ANKH,ATP13A2,B2M,CAMK2D,CCNA2,CDK1,CRHBP,CYP1A1,DHFR,EDN1,GCH1,HESX1,IL18BP,KCNJ10,KLF4,LRRK2,MMP9,MT2A,NCF1,P2RX4,P2RX7,PLSCR1,SLC11A1,SLC12A3,STAT1,SUCNR1,SYT1,SYT6,VCAM1,ZC3H12A"} {"GO.ID":"GO:0006869","Term":"lipid transport","Annotated":316,"Significant":29,"Expected":19.08,"Rank in p.value_classic":823,"p.value_elim":0.20081,"p.value_classic":0.01615,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,AGT,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,ATP8B1,CEACAM1,DAB2,EDN1,EEPD1,GHRL,GRAMD1B,OSBPL6,P2RX4,P2RX7,PLSCR1,PLSCR4,RBP7,SOAT1,TNFAIP8L3,TNFRSF11A,TTC39B,XKR6"} {"GO.ID":"GO:0044786","Term":"cell cycle DNA replication","Annotated":43,"Significant":10,"Expected":2.6,"Rank in p.value_classic":389,"p.value_elim":0.20114,"p.value_classic":0.00019,"genes":"BCL6,CDC45,CDT1,E2F8,FEN1,GINS1,MCM2,MCM4,MCM6,TK1"} {"GO.ID":"GO:0034097","Term":"response to cytokine","Annotated":781,"Significant":118,"Expected":47.17,"Rank in p.value_classic":19,"p.value_elim":0.20125,"p.value_classic":2.7e-21,"genes":"ACOD1,ACSL1,AIM2,APPL2,BRCA1,CALCOCO2,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD274,CD300LF,CD38,CD40,CD74,CEACAM1,CIITA,CRHBP,CSF1,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,EDN1,FAS,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,HELLS,HLA-DPA1,ICAM1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IRF1,IRF7,JAK2,JAK3,KLF4,LAMP3,LILRA1,LILRA2,LYN,MCM2,MEFV,MRAS,MT2A,MYBL2,NLRC5,NLRP12,NUB1,OAS2,OAS3,OSM,PADI2,PARP14,PARP9,PID1,PLSCR1,PML,PYHIN1,RAB20,RELB,RIPK2,RUFY4,SBNO2,SELL,SLC11A1,SNX10,SOCS1,SOX17,STAP1,STAT1,STAT2,TANK,TICAM2,TIFA,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TYMS,UBD,VCAM1,VEGFC,VRK2,XAF1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0007165","Term":"signal transduction","Annotated":4354,"Significant":352,"Expected":262.96,"Rank in p.value_classic":87,"p.value_elim":0.20164,"p.value_classic":7.2e-12,"genes":"ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,ANK2,APOL3,APPL2,ARAP2,ASB2,ATF3,AURKB,BANK1,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C3,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD101,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC45,CDC6,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CHAC1,CHMP4C,CHRD,CIBAR1,CISH,CLEC6A,CLSPN,COLEC12,COMP,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DDX60,DEPDC7,DEPTOR,DERL3,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DTL,DTNBP1,DTX3L,DYNLT1,E2F1,E2F2,ECEL1,EDA,EDN1,EME1,EPAS1,EPHB3,F2RL3,FAM13A,FAS,FBXO6,FCN1,FGD5,FLT3LG,FSTL4,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GBP7,GFRA2,GHRL,GLDN,GLIPR2,GNG2,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GTPBP1,GTSE1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,HORMAD1,HRH2,HSH2D,HTRA1,ICAM1,IFI27,IFI35,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL7,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JAK2,JAK3,KARS1,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAD2L1,MAML3,MCF2L,MCOLN2,MCTP2,MEFV,MERTK,MIR503,MMP9,MRAS,MTSS1,MUC1,MVP,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRGN,NRK,NRP1,NUCB1,NUF2,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,ONECUT2,OPTN,OR2I1P,ORC1,OSM,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PROK2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RIPK2,RNF213,RSAD2,RSU1,RXFP1,S100A13,S1PR1,SCIMP,SECTM1,SEMA6B,SEPTIN4,SESN3,SGPL1,SHCBP1,SIT1,SLAMF1,SLC12A3,SLC20A1,SOCS1,SOX17,SPC24,SPC25,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SUCNR1,SYNE1,TAGAP,TANK,TGM2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TPCN1,TRABD2A,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYRO3,UBD,VCAM1,VEGFC,VRK2,WDR76,WWP1,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:1901699","Term":"cellular response to nitrogen compound","Annotated":539,"Significant":41,"Expected":32.55,"Rank in p.value_classic":1261,"p.value_elim":0.20166,"p.value_classic":0.07456,"genes":"AGT,APPL2,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CDC6,CEACAM1,COLEC12,CRHBP,DTNBP1,EDN1,GHRL,GNG2,ICAM1,IFIH1,JAK2,JAK3,KLF4,LRRK2,LYN,NOD2,NR4A3,P2RX4,P2RX7,PDE3B,PDK4,PID1,PNPLA3,PXN,RALB,RAPGEF2,RIPK2,SESN3,SOCS1,STAMBPL1,STAT1,TGM2,VCAM1,XRN1"} {"GO.ID":"GO:0002861","Term":"regulation of inflammatory response to antigenic stimulus","Annotated":38,"Significant":8,"Expected":2.3,"Rank in p.value_classic":534,"p.value_elim":0.20202,"p.value_classic":0.00165,"genes":"C3,CD28,HLA-DRB1,HLA-E,KARS1,LTA,LYN,NOD2"} {"GO.ID":"GO:0046605","Term":"regulation of centrosome cycle","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1865,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"ATF5,BRCA1,CCNF,CHMP4C,WDR62"} {"GO.ID":"GO:0045600","Term":"positive regulation of fat cell differentiation","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1866,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"CDS1,LPL,LRP5,PIM1,ZC3H12A"} {"GO.ID":"GO:0050818","Term":"regulation of coagulation","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1867,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"CEACAM1,EDN1,ENPP4,SERPING1,THBD"} {"GO.ID":"GO:0032410","Term":"negative regulation of transporter activity","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1868,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"CAMK2D,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0070613","Term":"regulation of protein processing","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1869,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"ADAM8,CARD16,CHAC1,LRRK2,S100A10"} {"GO.ID":"GO:0017156","Term":"calcium-ion regulated exocytosis","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1870,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"CADPS2,SCIN,STX1A,SYT1,SYT6"} {"GO.ID":"GO:1903556","Term":"negative regulation of tumor necrosis factor superfamily cytokine production","Annotated":52,"Significant":5,"Expected":3.14,"Rank in p.value_classic":1871,"p.value_elim":0.20232,"p.value_classic":0.20373,"genes":"CD274,GHRL,NOD2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:1901652","Term":"response to peptide","Annotated":415,"Significant":33,"Expected":25.06,"Rank in p.value_classic":1206,"p.value_elim":0.20271,"p.value_classic":0.06396,"genes":"AGT,APPL2,CASP4,CCNA2,CD40,CDC6,CEACAM1,CRHBP,EDN1,EGR2,GHRL,ICAM1,JAK2,JAK3,KLF4,LRP5,LYN,MMP9,NOD2,NR4A3,PDE3B,PDK4,PID1,PNPLA3,PXN,RIPK2,SESN3,SOCS1,STAT1,STAT2,TNFRSF11A,TNFSF10,VCAM1"} {"GO.ID":"GO:0010634","Term":"positive regulation of epithelial cell migration","Annotated":137,"Significant":11,"Expected":8.27,"Rank in p.value_classic":1886,"p.value_elim":0.20319,"p.value_classic":0.20544,"genes":"AGT,CD40,EDN1,ENPP2,GLIPR2,HBEGF,MMP9,NRP1,P2RX4,VEGFC,ZC3H12A"} {"GO.ID":"GO:0044784","Term":"metaphase/anaphase transition of cell cycle","Annotated":92,"Significant":11,"Expected":5.56,"Rank in p.value_classic":895,"p.value_elim":0.20325,"p.value_classic":0.02248,"genes":"AURKB,BIRC5,BUB1B,CDC6,CENPF,MAD2L1,NDC80,NUF2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0045652","Term":"regulation of megakaryocyte differentiation","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1874,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"FAXDC2,SCIN,TESC"} {"GO.ID":"GO:0034311","Term":"diol metabolic process","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1875,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"DHFR,GCH1,NAAA"} {"GO.ID":"GO:0070293","Term":"renal absorption","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1876,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"CTNS,EDN1,SLC12A3"} {"GO.ID":"GO:0045922","Term":"negative regulation of fatty acid metabolic process","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1877,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"APPL2,BRCA1,CEACAM1"} {"GO.ID":"GO:0050858","Term":"negative regulation of antigen receptor-mediated signaling pathway","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1878,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"BTN2A2,CEACAM1,GBP1"} {"GO.ID":"GO:0050832","Term":"defense response to fungus","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1879,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"CLEC6A,CX3CR1,ZBP1"} {"GO.ID":"GO:1900745","Term":"positive regulation of p38MAPK cascade","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1880,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"GADD45B,NCF1,ZC3H12A"} {"GO.ID":"GO:0071354","Term":"cellular response to interleukin-6","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1881,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"JAK2,PID1,SBNO2"} {"GO.ID":"GO:0046320","Term":"regulation of fatty acid oxidation","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1882,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"APPL2,NR4A3,PDK4"} {"GO.ID":"GO:0046461","Term":"neutral lipid catabolic process","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1883,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"LPL,PLB1,PNPLA3"} {"GO.ID":"GO:0046464","Term":"acylglycerol catabolic process","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1884,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"LPL,PLB1,PNPLA3"} {"GO.ID":"GO:0050901","Term":"leukocyte tethering or rolling","Annotated":26,"Significant":3,"Expected":1.57,"Rank in p.value_classic":1885,"p.value_elim":0.20424,"p.value_classic":0.20527,"genes":"CX3CR1,SELL,VCAM1"} {"GO.ID":"GO:0150078","Term":"positive regulation of neuroinflammatory response","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1887,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"LRRK2,STAP1"} {"GO.ID":"GO:0043031","Term":"negative regulation of macrophage activation","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1888,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"IL31RA,ZC3H12A"} {"GO.ID":"GO:1900376","Term":"regulation of secondary metabolite biosynthetic process","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1889,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CTNS,RAPGEF2"} {"GO.ID":"GO:0048021","Term":"regulation of melanin biosynthetic process","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1890,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CTNS,RAPGEF2"} {"GO.ID":"GO:0043455","Term":"regulation of secondary metabolic process","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1891,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CTNS,RAPGEF2"} {"GO.ID":"GO:0036005","Term":"response to macrophage colony-stimulating factor","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1892,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CSF1,STAP1"} {"GO.ID":"GO:0043201","Term":"response to leucine","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1893,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"SESN3,STAMBPL1"} {"GO.ID":"GO:0071380","Term":"cellular response to prostaglandin E stimulus","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1894,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"GNG2,PTGER4"} {"GO.ID":"GO:2000105","Term":"positive regulation of DNA-templated DNA replication","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1895,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CDT1,E2F8"} {"GO.ID":"GO:0051444","Term":"negative regulation of ubiquitin-protein transferase activity","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1896,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"DTX3L,MAD2L1"} {"GO.ID":"GO:0085020","Term":"protein K6-linked ubiquitination","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1897,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"BRCA1,UBE2T"} {"GO.ID":"GO:0042559","Term":"pteridine-containing compound biosynthetic process","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1898,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0002524","Term":"hypersensitivity","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1899,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"C3,HLA-E"} {"GO.ID":"GO:0001833","Term":"inner cell mass cell proliferation","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1900,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"GINS1,NCAPG2"} {"GO.ID":"GO:0002679","Term":"respiratory burst involved in defense response","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1901,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"NCF1,SLAMF8"} {"GO.ID":"GO:0006287","Term":"base-excision repair, gap-filling","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1902,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"FEN1,POLB"} {"GO.ID":"GO:1903894","Term":"regulation of IRE1-mediated unfolded protein response","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1903,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"AGR2,BCL2L11"} {"GO.ID":"GO:0071880","Term":"adenylate cyclase-activating adrenergic receptor signaling pathway","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1904,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"PDE4B,RAPGEF2"} {"GO.ID":"GO:0048681","Term":"negative regulation of axon regeneration","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1905,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"KREMEN1,RTN4RL1"} {"GO.ID":"GO:0045723","Term":"positive regulation of fatty acid biosynthetic process","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1906,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"CD74,SLC45A3"} {"GO.ID":"GO:0019430","Term":"removal of superoxide radicals","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1907,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0097501","Term":"stress response to metal ion","Annotated":14,"Significant":2,"Expected":0.85,"Rank in p.value_classic":1908,"p.value_elim":0.20491,"p.value_classic":0.2057,"genes":"MT2A,SLC11A1"} {"GO.ID":"GO:0097194","Term":"execution phase of apoptosis","Annotated":66,"Significant":6,"Expected":3.99,"Rank in p.value_classic":1909,"p.value_elim":0.20563,"p.value_classic":0.20723,"genes":"CASP4,CASP7,PLSCR1,TOP2A,XKR6,ZC3H12A"} {"GO.ID":"GO:2001259","Term":"positive regulation of cation channel activity","Annotated":39,"Significant":4,"Expected":2.36,"Rank in p.value_classic":1910,"p.value_elim":0.20625,"p.value_classic":0.2075,"genes":"ANK2,CTSS,EDN1,TRDN"} {"GO.ID":"GO:2000300","Term":"regulation of synaptic vesicle exocytosis","Annotated":39,"Significant":4,"Expected":2.36,"Rank in p.value_classic":1911,"p.value_elim":0.20625,"p.value_classic":0.2075,"genes":"DTNBP1,LRRK2,SV2B,SYT1"} {"GO.ID":"GO:0036230","Term":"granulocyte activation","Annotated":39,"Significant":4,"Expected":2.36,"Rank in p.value_classic":1912,"p.value_elim":0.20625,"p.value_classic":0.2075,"genes":"CCL5,IL15,KARS1,LILRA2"} {"GO.ID":"GO:0090257","Term":"regulation of muscle system process","Annotated":167,"Significant":13,"Expected":10.09,"Rank in p.value_classic":1913,"p.value_elim":0.20709,"p.value_classic":0.20958,"genes":"AGT,ANK2,CAMK2D,EDN1,GHRL,KCNJ2,NR4A3,P2RX4,PDE4B,PROK2,SRI,TIFAB,ZC3H12A"} {"GO.ID":"GO:0043410","Term":"positive regulation of MAPK cascade","Annotated":371,"Significant":36,"Expected":22.41,"Rank in p.value_classic":606,"p.value_elim":0.20937,"p.value_classic":0.00331,"genes":"ADAM8,BANK1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,EDN1,GADD45B,GAREM1,GHRL,GLIPR2,GPR183,HGF,HLA-DRB1,ICAM1,IQGAP3,JAK2,LRRK2,NCF1,NECAB2,NOD2,NRK,NRP1,OSM,P2RX7,RAPGEF2,RIPK2,SCIMP,SLAMF1,TNFAIP8L3,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0007265","Term":"Ras protein signal transduction","Annotated":109,"Significant":9,"Expected":6.58,"Rank in p.value_classic":1914,"p.value_elim":0.21014,"p.value_classic":0.21218,"genes":"CCNA2,CSF1,IQGAP3,KITLG,MRAS,RALB,RAPGEF2,RASGEF1C,RASGRF1"} {"GO.ID":"GO:0061640","Term":"cytoskeleton-dependent cytokinesis","Annotated":109,"Significant":9,"Expected":6.58,"Rank in p.value_classic":1915,"p.value_elim":0.21014,"p.value_classic":0.21218,"genes":"ANLN,AURKB,BIRC5,CHMP4C,IQGAP3,KIF23,NUSAP1,SEPTIN4,STMN1"} {"GO.ID":"GO:0044772","Term":"mitotic cell cycle phase transition","Annotated":401,"Significant":43,"Expected":24.22,"Rank in p.value_classic":385,"p.value_elim":0.21039,"p.value_classic":0.00017,"genes":"ABCB1,ANLN,APPL2,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CDC25A,CDC6,CDCA5,CDK1,CDKN2C,CENPF,CHMP4C,CLSPN,CYP1A1,DTL,E2F1,FAM107A,GTSE1,IQGAP3,KLF4,MAD2L1,MUC1,NDC80,NPM2,NUF2,ORC1,PKMYT1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TICRR,UBD,WEE1,ZWINT"} {"GO.ID":"GO:0060284","Term":"regulation of cell development","Annotated":702,"Significant":71,"Expected":42.4,"Rank in p.value_classic":288,"p.value_elim":0.21256,"p.value_classic":0.00001,"genes":"ADAM8,APPL2,ASCL2,B2M,BCL6,BHLHE41,BTN2A2,CD101,CD28,CD74,CD80,CD83,CDH5,CEACAM1,CSF1,CTLA4,CX3CR1,CYLD,CYSLTR1,DAB1,DLL1,DYNLT1,EGR2,FAXDC2,FGL2,FSTL4,HAPLN3,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,IRF7,JAK3,KITLG,LAG3,LILRB3,LRRK2,LTA,LYN,NRP1,PLXNA2,RAPGEF2,RIPK2,S100A10,SCIN,SEMA6B,SLAMF8,SOCS1,STAT1,TAL1,TBX21,TESC,TGM2,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,VCAN,VEGFC,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0003013","Term":"circulatory system process","Annotated":457,"Significant":40,"Expected":27.6,"Rank in p.value_classic":778,"p.value_elim":0.21271,"p.value_classic":0.01152,"genes":"ABCB1,ABCG2,ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CD38,CDH5,CEACAM1,COMP,CXADR,CXCL10,CYSLTR1,DLL1,EDN1,EPAS1,ERAP2,GCH1,GHRL,GJD3,HBEGF,HRH2,KCNE5,KCNJ2,LRP5,MYOF,NPR1,P2RX4,PDE4B,SCN4B,SERPING1,SLC2A5,SPTBN4,SRI,STAT1,SUCNR1,TRDN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0006949","Term":"syncytium formation","Annotated":53,"Significant":5,"Expected":3.2,"Rank in p.value_classic":1917,"p.value_elim":0.21321,"p.value_classic":0.21468,"genes":"ADAMTS15,CXCL10,CXCL9,SBNO2,SH3PXD2A"} {"GO.ID":"GO:0019674","Term":"NAD metabolic process","Annotated":53,"Significant":5,"Expected":3.2,"Rank in p.value_classic":1918,"p.value_elim":0.21321,"p.value_classic":0.21468,"genes":"CD38,IDO1,IDO2,PARP10,PARP9"} {"GO.ID":"GO:0016101","Term":"diterpenoid metabolic process","Annotated":53,"Significant":5,"Expected":3.2,"Rank in p.value_classic":1919,"p.value_elim":0.21321,"p.value_classic":0.21468,"genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"GO.ID":"GO:0061008","Term":"hepaticobiliary system development","Annotated":124,"Significant":10,"Expected":7.49,"Rank in p.value_classic":1920,"p.value_elim":0.21379,"p.value_classic":0.21599,"genes":"CEACAM1,CYP1A1,DNAAF1,E2F8,FGL1,HGF,IGF2R,ONECUT2,SOX17,TYMS"} {"GO.ID":"GO:0045444","Term":"fat cell differentiation","Annotated":198,"Significant":15,"Expected":11.96,"Rank in p.value_classic":1924,"p.value_elim":0.21418,"p.value_classic":0.21694,"genes":"ATF5,CDS1,E2F1,EGR2,KLF4,LAMB3,LPL,LRP5,NR4A3,PIM1,PNPLA3,PSMB8,SOCS1,STEAP4,ZC3H12A"} {"GO.ID":"GO:0070231","Term":"T cell apoptotic process","Annotated":52,"Significant":11,"Expected":3.14,"Rank in p.value_classic":395,"p.value_elim":0.21503,"p.value_classic":0.00022,"genes":"ADAM8,BCL2L11,CCL5,CD274,EBF4,FAS,GIMAP8,IDO1,JAK3,P2RX7,PDCD1"} {"GO.ID":"GO:0072091","Term":"regulation of stem cell proliferation","Annotated":67,"Significant":6,"Expected":4.05,"Rank in p.value_classic":1921,"p.value_elim":0.2153,"p.value_classic":0.21694,"genes":"CDKN2C,KITLG,OVOL1,PIM1,SOX17,VEGFC"} {"GO.ID":"GO:0009593","Term":"detection of chemical stimulus","Annotated":67,"Significant":6,"Expected":4.05,"Rank in p.value_classic":1922,"p.value_elim":0.2153,"p.value_classic":0.21694,"genes":"C4B,NOD2,OR2I1P,PKD1L3,RTP4,SYT1"} {"GO.ID":"GO:1902476","Term":"chloride transmembrane transport","Annotated":67,"Significant":6,"Expected":4.05,"Rank in p.value_classic":1923,"p.value_elim":0.2153,"p.value_classic":0.21694,"genes":"ANO4,APOL1,CLIC5,GABRA3,OCA2,SLC12A3"} {"GO.ID":"GO:0072676","Term":"lymphocyte migration","Annotated":101,"Significant":18,"Expected":6.1,"Rank in p.value_classic":322,"p.value_elim":0.21659,"p.value_classic":0.00003,"genes":"ADAM8,ASCL2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CXCL10,CXCL11,GPR183,HSD3B7,ICAM1,KLRK1,PADI2,S1PR1,TBX21,TNFRSF14"} {"GO.ID":"GO:0045807","Term":"positive regulation of endocytosis","Annotated":123,"Significant":19,"Expected":7.43,"Rank in p.value_classic":373,"p.value_elim":0.21693,"p.value_classic":0.00014,"genes":"APPL2,B2M,C2,C3,C4A,C4B,CD300LF,DAB2,DLL1,DTNBP1,FCN1,IL15,IL15RA,LRRK2,MERTK,NOD2,SLC11A1,STAP1,SYNE1"} {"GO.ID":"GO:0002820","Term":"negative regulation of adaptive immune response","Annotated":50,"Significant":15,"Expected":3.02,"Rank in p.value_classic":190,"p.value_elim":0.21722,"p.value_classic":1.4e-07,"genes":"ASCL2,BCL6,CD80,CEACAM1,CR1L,HLA-F,HLA-G,IL4I1,JAK3,NOD2,PARP3,SLAMF1,TBX21,TNFRSF14,ZC3H12A"} {"GO.ID":"GO:0043903","Term":"regulation of biological process involved in symbiotic interaction","Annotated":46,"Significant":9,"Expected":2.78,"Rank in p.value_classic":523,"p.value_elim":0.21758,"p.value_classic":0.00149,"genes":"CD74,CIITA,FCN1,HLA-DRB1,IFITM1,IFITM2,IFITM3,TRIM22,TRIM31"} {"GO.ID":"GO:0031960","Term":"response to corticosteroid","Annotated":110,"Significant":9,"Expected":6.64,"Rank in p.value_classic":1925,"p.value_elim":0.21762,"p.value_classic":0.21972,"genes":"BCL2L11,EDN1,FAM107A,IL1RN,JAK2,PTPRU,SLC12A3,SSTR2,TYMS"} {"GO.ID":"GO:0034142","Term":"toll-like receptor 4 signaling pathway","Annotated":53,"Significant":9,"Expected":3.2,"Rank in p.value_classic":636,"p.value_elim":0.21781,"p.value_classic":0.00411,"genes":"ACOD1,APPL2,IFI35,LILRA2,LYN,NMI,RIPK2,SCIMP,TICAM2"} {"GO.ID":"GO:0060761","Term":"negative regulation of response to cytokine stimulus","Annotated":72,"Significant":12,"Expected":4.35,"Rank in p.value_classic":503,"p.value_elim":0.21832,"p.value_classic":0.00117,"genes":"CARD16,CCL5,CYLD,IL1RN,KLF4,NLRC5,OAS3,PADI2,PARP14,STAP1,STAT2,TANK"} {"GO.ID":"GO:0002418","Term":"immune response to tumor cell","Annotated":21,"Significant":6,"Expected":1.27,"Rank in p.value_classic":508,"p.value_elim":0.21907,"p.value_classic":0.00118,"genes":"CD274,CEACAM1,HLA-A,HLA-DRB1,IL12A,IL4I1"} {"GO.ID":"GO:0070192","Term":"chromosome organization involved in meiotic cell cycle","Annotated":40,"Significant":4,"Expected":2.42,"Rank in p.value_classic":1927,"p.value_elim":0.21911,"p.value_classic":0.22042,"genes":"CCNE2,DMC1,HORMAD1,NCAPH"} {"GO.ID":"GO:1903350","Term":"response to dopamine","Annotated":40,"Significant":4,"Expected":2.42,"Rank in p.value_classic":1928,"p.value_elim":0.21911,"p.value_classic":0.22042,"genes":"DTNBP1,GNG2,LRRK2,TGM2"} {"GO.ID":"GO:0043542","Term":"endothelial cell migration","Annotated":199,"Significant":15,"Expected":12.02,"Rank in p.value_classic":1939,"p.value_elim":0.21972,"p.value_classic":0.22253,"genes":"AGT,AMOT,CD40,CDH5,CEACAM1,EDN1,GLUL,KLF4,MIR503,NRP1,P2RX4,PRKX,PXN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0010165","Term":"response to X-ray","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1929,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"KARS1,THBD,XRCC2"} {"GO.ID":"GO:0010765","Term":"positive regulation of sodium ion transport","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1930,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"ATP1B2,SCN4B,TESC"} {"GO.ID":"GO:0045923","Term":"positive regulation of fatty acid metabolic process","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1931,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"CD74,NR4A3,SLC45A3"} {"GO.ID":"GO:0070741","Term":"response to interleukin-6","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1932,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"JAK2,PID1,SBNO2"} {"GO.ID":"GO:1904376","Term":"negative regulation of protein localization to cell periphery","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1933,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"DAB2,GBP1,PID1"} {"GO.ID":"GO:0010971","Term":"positive regulation of G2/M transition of mitotic cell cycle","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1934,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"CDC25A,CDK1,DTL"} {"GO.ID":"GO:0001709","Term":"cell fate determination","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1935,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"DLL1,KLF4,SOX17"} {"GO.ID":"GO:0006221","Term":"pyrimidine nucleotide biosynthetic process","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1936,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"CMPK2,SLC4A7,TYMS"} {"GO.ID":"GO:0035872","Term":"nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","Annotated":27,"Significant":3,"Expected":1.63,"Rank in p.value_classic":1937,"p.value_elim":0.22024,"p.value_classic":0.22134,"genes":"CYLD,NOD2,RIPK2"} {"GO.ID":"GO:0007162","Term":"negative regulation of cell adhesion","Annotated":243,"Significant":35,"Expected":14.68,"Rank in p.value_classic":235,"p.value_elim":0.22062,"p.value_classic":1.4e-06,"genes":"ASCL2,BCL6,BTN2A2,CD274,CD74,CD80,CEACAM1,CTLA4,DAB1,FAM107A,FGL1,FGL2,GBP1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL1RN,IL4I1,IRF1,JAK2,JAK3,KLF4,LAG3,MIR503,MUC1,PDCD1LG2,PDE3B,PLXNA2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,ZC3H12A"} {"GO.ID":"GO:1903706","Term":"regulation of hemopoiesis","Annotated":356,"Significant":49,"Expected":21.5,"Rank in p.value_classic":171,"p.value_elim":0.22133,"p.value_classic":4.8e-08,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CD101,CD28,CD74,CD80,CD83,CEACAM1,CSF1,CTLA4,CYLD,DLL1,FAXDC2,FGL2,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,IRF7,JAK3,KITLG,LAG3,LILRB3,LYN,RIPK2,SCIN,SLAMF8,SOCS1,STAT1,TAL1,TBX21,TESC,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0097529","Term":"myeloid leukocyte migration","Annotated":190,"Significant":31,"Expected":11.48,"Rank in p.value_classic":209,"p.value_elim":0.2215,"p.value_classic":3.7e-07,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,KITLG,LYN,MCOLN2,MTUS1,NOD2,P2RX4,PDE4B,PTGER4,SLAMF1,SLAMF8,STAP1,TNFAIP6,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0002456","Term":"T cell mediated immunity","Annotated":108,"Significant":26,"Expected":6.52,"Rank in p.value_classic":121,"p.value_elim":0.22164,"p.value_classic":8.2e-10,"genes":"B2M,BTN3A2,BTN3A3,CD1A,CD1C,CD80,CEACAM1,CR1L,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL4I1,NOD2,P2RX7,RSAD2,SLAMF1,TAP2,TBX21"} {"GO.ID":"GO:0051707","Term":"response to other organism","Annotated":1142,"Significant":186,"Expected":68.97,"Rank in p.value_classic":3,"p.value_elim":0.22206,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,B2M,BANK1,BATF2,BATF3,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD40,CD74,CD80,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,CMPK2,COLEC12,CSF1,CSF2RB,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,DDX60,DTX3L,EDN1,FAM20A,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GRAMD4,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL18BP,IL27,IL31RA,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LITAF,LPL,LTA,LYN,MCOLN2,MEFV,MMP9,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,P2RX7,PARP14,PARP9,PDCD1LG2,PDE4B,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PML,PPM1E,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SBNO2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,STAT1,STAT2,STMN1,TANK,TAP2,TBX21,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM255A,TNFRSF11A,TNFRSF14,TNFSF8,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,VCAM1,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0007166","Term":"cell surface receptor signaling pathway","Annotated":2196,"Significant":203,"Expected":132.63,"Rank in p.value_classic":99,"p.value_elim":0.22275,"p.value_classic":3.9e-11,"genes":"ACOD1,ACSL1,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIM2,AMER1,APPL2,ATF3,BANK1,BCL2A1,BCL2L11,BCL2L14,BCL6,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD101,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CDH5,CEACAM1,CELSR1,CHAC1,CHRD,CIBAR1,CLEC6A,COMP,CSF1,CSF2RB,CTLA4,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYSLTR1,DAB1,DAB2,DEPTOR,DKK2,DLL1,DTX3L,EDA,EDN1,EPHB3,FAS,FCN1,FSTL4,FYB1,G0S2,GAREM1,GBP1,GBP7,GFRA2,GHRL,GRIN3A,GRM8,HBEGF,HESX1,HGF,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,HTRA1,ICAM1,IFI27,IFI35,IFIH1,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INSYN2A,IRF1,IRF7,ITGA7,ITGB5,ITK,JAK2,JAK3,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LILRA1,LILRA2,LILRB3,LRP5,LRRK2,LYN,MAML3,MERTK,MIR503,MMP9,MTSS1,MVP,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRP1,OAS2,OAS3,ONECUT2,OSM,P2RX4,P2RX7,P2RY14,PADI2,PARP14,PARP9,PDCD1LG2,PDE4B,PDK4,PID1,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,PTPRU,PXN,RALB,RAPGEF2,REPS2,RIPK2,RNF213,SCIMP,SEMA6B,SESN3,SGPL1,SHCBP1,SLAMF1,SOCS1,SOX17,STAP1,STAT1,STAT2,STMN1,STX1A,SYNE1,TANK,TICAM2,TIFA,TIFAB,TLR5,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TRABD2A,TSPAN15,TSPAN32,TYRO3,VEGFC,VRK2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0002791","Term":"regulation of peptide secretion","Annotated":140,"Significant":11,"Expected":8.46,"Rank in p.value_classic":1941,"p.value_elim":0.22301,"p.value_classic":0.22539,"genes":"CCL5,CD38,CD74,CRHBP,GHRL,HLA-DRB1,JAK2,LRP5,SIDT2,SRI,STX1A"} {"GO.ID":"GO:0051897","Term":"positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction","Annotated":140,"Significant":11,"Expected":8.46,"Rank in p.value_classic":1942,"p.value_elim":0.22301,"p.value_classic":0.22539,"genes":"ADAM8,AGT,CCL5,CD28,CX3CR1,HBEGF,HGF,JAK2,NCF1,OSM,P2RX4"} {"GO.ID":"GO:0002067","Term":"glandular epithelial cell differentiation","Annotated":54,"Significant":5,"Expected":3.26,"Rank in p.value_classic":1944,"p.value_elim":0.22428,"p.value_classic":0.2258,"genes":"AGR2,DLL1,IL31RA,KLF4,SIDT2"} {"GO.ID":"GO:0001570","Term":"vasculogenesis","Annotated":68,"Significant":6,"Expected":4.11,"Rank in p.value_classic":1945,"p.value_elim":0.22511,"p.value_classic":0.2268,"genes":"AMOT,CEACAM1,NRP1,RAPGEF2,SGPL1,SOX17"} {"GO.ID":"GO:0000302","Term":"response to reactive oxygen species","Annotated":170,"Significant":13,"Expected":10.27,"Rank in p.value_classic":1949,"p.value_elim":0.22513,"p.value_classic":0.22776,"genes":"CDK1,DHFR,EDN1,GCH1,HGF,IL18BP,KLF4,LRRK2,MMP9,NCF1,PXN,SESN3,STAT1"} {"GO.ID":"GO:0038127","Term":"ERBB signaling pathway","Annotated":111,"Significant":9,"Expected":6.7,"Rank in p.value_classic":1946,"p.value_elim":0.22521,"p.value_classic":0.22735,"genes":"AGR2,AGT,CEACAM1,GAREM1,HBEGF,MMP9,MVP,RALB,REPS2"} {"GO.ID":"GO:2001056","Term":"positive regulation of cysteine-type endopeptidase activity","Annotated":111,"Significant":9,"Expected":6.7,"Rank in p.value_classic":1947,"p.value_elim":0.22521,"p.value_classic":0.22735,"genes":"AIM2,FAS,GRAMD4,JAK2,MEFV,NLRP12,PMAIP1,RIPK2,TNFSF10"} {"GO.ID":"GO:0006865","Term":"amino acid transport","Annotated":111,"Significant":9,"Expected":6.7,"Rank in p.value_classic":1948,"p.value_elim":0.22521,"p.value_classic":0.22735,"genes":"CTNS,DTNBP1,KCNJ10,LRP5,P2RX7,SERINC5,SLC11A1,SLC16A10,SLC6A12"} {"GO.ID":"GO:0046486","Term":"glycerolipid metabolic process","Annotated":322,"Significant":23,"Expected":19.45,"Rank in p.value_classic":1979,"p.value_elim":0.22631,"p.value_classic":0.22993,"genes":"ACSL1,C3,CDS1,CISH,DGAT2,ENPP2,G6PC1,GK,LCLAT1,LPL,NAAA,PCYT1A,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLSCR1,PNPLA3,SERINC5,SOCS1,TMEM150A,TNFAIP8L3"} {"GO.ID":"GO:0010646","Term":"regulation of cell communication","Annotated":2848,"Significant":214,"Expected":172.01,"Rank in p.value_classic":378,"p.value_elim":0.22645,"p.value_classic":0.00015,"genes":"ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,ANK2,APOL3,APPL2,ASIC1,ATF3,AURKB,BANK1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,C3,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CEACAM1,CHAC1,CHRD,CIBAR1,CISH,CLEC6A,CRHBP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXADR,CYLD,DAB1,DAB2,DDX60,DEPTOR,DHRS3,DKK2,DLGAP3,DLL1,DNM1,DTNBP1,DYNLT1,DYSF,EDA,EDN1,EGR2,ERC2,F2RL3,FAM107A,FAM13A,FAS,FGD5,FSTL4,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GBP7,GHRL,GLIPR2,GPR183,GRAMD4,GRIN3A,GRM8,HBEGF,HCAR2,HELLS,HGF,HLA-DRB1,HLA-G,HTRA1,ICAM1,IFI35,IFIT5,IFT122,IL12A,IL1RN,IL7,INA,IQGAP3,IRF1,IRF4,IRF7,ITSN1,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KREMEN1,LBH,LILRA2,LITAF,LRP5,LRRK2,LYN,MAD2L1,MCF2L,MCTP2,MEFV,MIR503,MMP9,MUC1,MVP,MYOF,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP9,PDE3B,PDE4B,PID1,PIM1,PLEK,PLSCR1,PMAIP1,PML,PRRT2,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RGS18,RIPK2,RNF213,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SESN3,SIDT2,SLAMF1,SLC20A1,SOCS1,SOX17,SRI,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SV2B,SYNE1,SYT1,TAGAP,TANK,TGM2,TICAM2,TIFA,TIFAB,TLR7,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFSF10,TRABD2A,TRDN,TRIM22,TRIM31,TSPAN15,TYMP,TYRO3,UBD,VEGFC,VRK2,WDR76,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0048285","Term":"organelle fission","Annotated":418,"Significant":46,"Expected":25.25,"Rank in p.value_classic":343,"p.value_elim":0.22654,"p.value_classic":0.00006,"genes":"ANLN,AURKB,BCL2L11,BIRC5,BUB1B,CCNE2,CD28,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,DAZL,DMC1,EDN1,EME1,EML4,HORMAD1,KIF11,KIF18B,KIF23,LRP5,LRRK2,MAD2L1,MEIKIN,MKI67,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,PKMYT1,PRC1,RAD54B,RAD54L,SPC24,SPC25,STAT2,TDRD9,TOP2A,UHRF1,ZWINT"} {"GO.ID":"GO:0009125","Term":"nucleoside monophosphate catabolic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1950,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"DPYS,TYMP"} {"GO.ID":"GO:0023035","Term":"CD40 signaling pathway","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1951,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CD40,SLAMF1"} {"GO.ID":"GO:0010738","Term":"regulation of protein kinase A signaling","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1952,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"AKAP7,LRRK2"} {"GO.ID":"GO:0010881","Term":"regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1953,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"ANK2,CAMK2D"} {"GO.ID":"GO:0140131","Term":"positive regulation of lymphocyte chemotaxis","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1954,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CCL5,CCL7"} {"GO.ID":"GO:0010544","Term":"negative regulation of platelet activation","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1955,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CEACAM1,THBD"} {"GO.ID":"GO:0034162","Term":"toll-like receptor 9 signaling pathway","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1956,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"GRAMD4,RSAD2"} {"GO.ID":"GO:1903083","Term":"protein localization to condensed chromosome","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1957,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"AURKB,CDK1"} {"GO.ID":"GO:2000353","Term":"positive regulation of endothelial cell apoptotic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1958,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CD40,HLA-G"} {"GO.ID":"GO:0042403","Term":"thyroid hormone metabolic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1959,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CTNS,SLC16A10"} {"GO.ID":"GO:1902033","Term":"regulation of hematopoietic stem cell proliferation","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1960,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"KITLG,PIM1"} {"GO.ID":"GO:0070571","Term":"negative regulation of neuron projection regeneration","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1961,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"KREMEN1,RTN4RL1"} {"GO.ID":"GO:0014841","Term":"skeletal muscle satellite cell proliferation","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1962,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"JAK2,NDC80"} {"GO.ID":"GO:0047484","Term":"regulation of response to osmotic stress","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1963,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"ABCB1,TIFAB"} {"GO.ID":"GO:0034501","Term":"protein localization to kinetochore","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1964,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"AURKB,CDK1"} {"GO.ID":"GO:0042730","Term":"fibrinolysis","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1965,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"SERPING1,THBD"} {"GO.ID":"GO:0032897","Term":"negative regulation of viral transcription","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1966,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"IFITM3,TRIM31"} {"GO.ID":"GO:0021783","Term":"preganglionic parasympathetic fiber development","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1967,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"EGR2,NRP1"} {"GO.ID":"GO:0045346","Term":"regulation of MHC class II biosynthetic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1968,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CIITA,JAK2"} {"GO.ID":"GO:0042573","Term":"retinoic acid metabolic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1969,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CYP1A1,DHRS9"} {"GO.ID":"GO:1902166","Term":"negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1970,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CD74,MUC1"} {"GO.ID":"GO:0007252","Term":"I-kappaB phosphorylation","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1971,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CX3CR1,TLR7"} {"GO.ID":"GO:0010042","Term":"response to manganese ion","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1972,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"ATP13A2,LRRK2"} {"GO.ID":"GO:0006750","Term":"glutathione biosynthetic process","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1973,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CHAC1,GGT5"} {"GO.ID":"GO:1903587","Term":"regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1974,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"IL12A,MIR503"} {"GO.ID":"GO:0016540","Term":"protein autoprocessing","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1975,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"CASP4,CTSL"} {"GO.ID":"GO:0006825","Term":"copper ion transport","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1976,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"SLC31A2,STEAP4"} {"GO.ID":"GO:0032905","Term":"transforming growth factor beta1 production","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1977,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0035809","Term":"regulation of urine volume","Annotated":15,"Significant":2,"Expected":0.91,"Rank in p.value_classic":1978,"p.value_elim":0.22757,"p.value_classic":0.22843,"genes":"EDN1,NPR1"} {"GO.ID":"GO:0039531","Term":"regulation of cytoplasmic pattern recognition receptor signaling pathway","Annotated":97,"Significant":8,"Expected":5.86,"Rank in p.value_classic":1980,"p.value_elim":0.22924,"p.value_classic":0.23126,"genes":"AURKB,DDX60,GBP2,GBP5,GRAMD4,MEFV,RSAD2,TRIM31"} {"GO.ID":"GO:0008637","Term":"apoptotic mitochondrial changes","Annotated":97,"Significant":8,"Expected":5.86,"Rank in p.value_classic":1981,"p.value_elim":0.22924,"p.value_classic":0.23126,"genes":"AIFM2,BCL2A1,BCL2L11,HGF,IFIT2,MMP9,PMAIP1,TNFSF10"} {"GO.ID":"GO:0006898","Term":"receptor-mediated endocytosis","Annotated":216,"Significant":16,"Expected":13.05,"Rank in p.value_classic":1983,"p.value_elim":0.23038,"p.value_classic":0.23338,"genes":"B2M,C3,CEACAM1,CLEC9A,CTSL,DAB2,DLL1,DNM1,DTNBP1,IGF2R,ITSN1,LYVE1,NECAB2,RALB,SCARF1,SYNE1"} {"GO.ID":"GO:0031099","Term":"regeneration","Annotated":156,"Significant":12,"Expected":9.42,"Rank in p.value_classic":1982,"p.value_elim":0.23082,"p.value_classic":0.23337,"genes":"CCNA2,CDK1,DHFR,IGF2R,JAK2,KLF4,KREMEN1,NR4A3,PTPRU,RTN4RL1,SCARF1,TYMS"} {"GO.ID":"GO:0051651","Term":"maintenance of location in cell","Annotated":186,"Significant":14,"Expected":11.23,"Rank in p.value_classic":1992,"p.value_elim":0.2313,"p.value_classic":0.23409,"genes":"ANK2,CAMK2D,CXCL10,CXCL11,CXCL9,F2RL3,LYN,P2RX7,PML,SCIN,SRI,SYNE1,TMSB10,TRDN"} {"GO.ID":"GO:0009314","Term":"response to radiation","Annotated":354,"Significant":25,"Expected":21.38,"Rank in p.value_classic":1996,"p.value_elim":0.23141,"p.value_classic":0.23526,"genes":"AURKB,BRCA1,CASP7,CCL7,CDC25A,CDS1,CTNS,CXCL10,DTL,FEN1,IL12A,KARS1,MMP9,PCLAF,PML,POLB,RAD54B,RAD54L,SYNE1,TANK,THBD,TICRR,TMEM109,VCAM1,XRCC2"} {"GO.ID":"GO:0043207","Term":"response to external biotic stimulus","Annotated":1143,"Significant":186,"Expected":69.03,"Rank in p.value_classic":4,"p.value_elim":0.23142,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,B2M,BANK1,BATF2,BATF3,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD40,CD74,CD80,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,CMPK2,COLEC12,CSF1,CSF2RB,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,DDX60,DTX3L,EDN1,FAM20A,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GRAMD4,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL18BP,IL27,IL31RA,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LITAF,LPL,LTA,LYN,MCOLN2,MEFV,MMP9,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,P2RX7,PARP14,PARP9,PDCD1LG2,PDE4B,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PML,PPM1E,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SBNO2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,STAT1,STAT2,STMN1,TANK,TAP2,TBX21,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM255A,TNFRSF11A,TNFRSF14,TNFSF8,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,VCAM1,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0030162","Term":"regulation of proteolysis","Annotated":494,"Significant":34,"Expected":29.84,"Rank in p.value_classic":1997,"p.value_elim":0.23158,"p.value_classic":0.23614,"genes":"ADAM8,AIM2,ATP13A2,CARD16,CHAC1,CTSL,CTSS,DAB2,FAS,GRAMD4,GSAP,JAK2,KLF4,LAMP3,LRRK2,LYN,MEFV,MMP9,NLRP12,NUB1,PMAIP1,PML,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RIPK2,S100A10,SERPING1,TANK,TNFSF10,TSPAN15"} {"GO.ID":"GO:0070228","Term":"regulation of lymphocyte apoptotic process","Annotated":53,"Significant":13,"Expected":3.2,"Rank in p.value_classic":289,"p.value_elim":0.23159,"p.value_classic":0.00001,"genes":"ADAM8,AURKB,BCL2L11,BCL6,CCL5,CD274,CD74,GIMAP8,IDO1,JAK3,LYN,P2RX7,PDCD1"} {"GO.ID":"GO:0045646","Term":"regulation of erythrocyte differentiation","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1984,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"B2M,LYN,STAT1,TAL1"} {"GO.ID":"GO:0030866","Term":"cortical actin cytoskeleton organization","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1985,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"ANLN,FMNL2,IQGAP3,PLEK"} {"GO.ID":"GO:2000351","Term":"regulation of endothelial cell apoptotic process","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1986,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"CD40,CDH5,HLA-G,ICAM1"} {"GO.ID":"GO:0002762","Term":"negative regulation of myeloid leukocyte differentiation","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1987,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"CEACAM1,LILRB3,LYN,TNFAIP6"} {"GO.ID":"GO:0001774","Term":"microglial cell activation","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1988,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"CX3CR1,JAK2,LRRK2,STAP1"} {"GO.ID":"GO:0061756","Term":"leukocyte adhesion to vascular endothelial cell","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1989,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"CX3CR1,KLF4,SELL,VCAM1"} {"GO.ID":"GO:0048662","Term":"negative regulation of smooth muscle cell proliferation","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1990,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"IL12A,KLF4,MIR503,NPR1"} {"GO.ID":"GO:0006749","Term":"glutathione metabolic process","Annotated":41,"Significant":4,"Expected":2.48,"Rank in p.value_classic":1991,"p.value_elim":0.23219,"p.value_classic":0.23355,"genes":"CHAC1,CTNS,GGT5,GSTK1"} {"GO.ID":"GO:0051492","Term":"regulation of stress fiber assembly","Annotated":83,"Significant":7,"Expected":5.01,"Rank in p.value_classic":1993,"p.value_elim":0.23268,"p.value_classic":0.23457,"genes":"NRP1,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0097306","Term":"cellular response to alcohol","Annotated":83,"Significant":7,"Expected":5.01,"Rank in p.value_classic":1994,"p.value_elim":0.23268,"p.value_classic":0.23457,"genes":"BRCA1,CCL7,GNG2,GRAMD1B,KLF4,PTGER4,XRN1"} {"GO.ID":"GO:0021700","Term":"developmental maturation","Annotated":247,"Significant":18,"Expected":14.92,"Rank in p.value_classic":2000,"p.value_elim":0.2337,"p.value_classic":0.23693,"genes":"C3,CDH5,CX3CR1,DAZL,DMC1,EDN1,EPAS1,GLDN,IL15,LRRK2,NRCAM,S1PR1,SCARF1,SNX10,SPTBN4,TAL1,TYMS,XYLT1"} {"GO.ID":"GO:0016032","Term":"viral process","Annotated":383,"Significant":50,"Expected":23.13,"Rank in p.value_classic":194,"p.value_elim":0.23375,"p.value_classic":1.9e-07,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CALCOCO2,CCL5,CCL8,CD28,CD74,CD80,CDK1,CHMP4C,CIITA,CTSL,CXADR,DYNLT1,FCN1,GBP7,HAVCR1,HLA-DRB1,ICAM1,IFI27,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,IGF2R,IRF7,ISG20,ITGB5,LAMP3,NRP1,OAS2,OAS3,PARP10,PARP9,PLSCR1,RSAD2,SLAMF1,STAT1,TNFRSF14,TOP2A,TPCN1,TRIM22,TRIM31,TYRO3,USP6NL,WWP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0002260","Term":"lymphocyte homeostasis","Annotated":67,"Significant":10,"Expected":4.05,"Rank in p.value_classic":699,"p.value_elim":0.2338,"p.value_classic":0.00661,"genes":"AIM2,BCL2L11,CD74,FAS,JAK3,LYN,P2RX7,PMAIP1,SIT1,TNFSF13B"} {"GO.ID":"GO:0010647","Term":"positive regulation of cell communication","Annotated":1464,"Significant":119,"Expected":88.42,"Rank in p.value_classic":427,"p.value_elim":0.23402,"p.value_classic":0.00037,"genes":"ADAM8,AGR2,AGT,AMER1,APOL3,APPL2,ATF3,AURKB,BANK1,BCL2L11,BIRC5,C3,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CIBAR1,CLEC6A,CSF1,CTNS,CTSL,CTSS,CX3CR1,CYLD,DAB2,DDX60,DKK2,DLL1,DTNBP1,EDA,EDN1,F2RL3,FAM107A,FAS,G0S2,GADD45B,GAREM1,GBP2,GBP5,GHRL,GLIPR2,GPR183,HBEGF,HCAR2,HGF,HLA-DRB1,ICAM1,IFI35,IFIT5,IL7,IQGAP3,IRF7,JAK2,KITLG,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MMP9,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OSM,P2RX4,P2RX7,PARP14,PARP9,PIM1,PMAIP1,PML,PYHIN1,RALB,RAPGEF2,RASGRF1,RIPK2,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SLAMF1,SLC20A1,SRI,STAMBPL1,STAP1,STX1A,SYT1,TGM2,TICAM2,TIFA,TLR7,TNFAIP8L3,TNFRSF11A,TNFSF10,TRDN,TRIM22,UBD,ZBP1,ZC3H12A"} {"GO.ID":"GO:0019079","Term":"viral genome replication","Annotated":122,"Significant":21,"Expected":7.37,"Rank in p.value_classic":291,"p.value_elim":0.23456,"p.value_classic":0.00001,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CCL8,CD28,GBP7,IFI27,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,OAS2,OAS3,PLSCR1,RSAD2,TOP2A,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0140353","Term":"lipid export from cell","Annotated":39,"Significant":7,"Expected":2.36,"Rank in p.value_classic":712,"p.value_elim":0.23456,"p.value_classic":0.00805,"genes":"AGT,DAB2,EDN1,GHRL,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0071900","Term":"regulation of protein serine/threonine kinase activity","Annotated":232,"Significant":17,"Expected":14.01,"Rank in p.value_classic":2009,"p.value_elim":0.23488,"p.value_classic":0.23801,"genes":"AGT,CCNA2,CCNE2,CCNF,CD40,CDC25A,CDC6,CDKN2C,EDN1,LRP5,LRRK2,LYN,PKIB,PKMYT1,RALB,RAPGEF2,TNFRSF11A"} {"GO.ID":"GO:0048511","Term":"rhythmic process","Annotated":232,"Significant":17,"Expected":14.01,"Rank in p.value_classic":2010,"p.value_elim":0.23488,"p.value_classic":0.23801,"genes":"ATF5,BHLHE41,BMAL2,C3orf70,CDK1,DTL,GHRL,GRIN3A,PML,PROK2,RELB,SGPL1,TNFAIP6,TNFRSF11A,TOP2A,TYMS,TYRO3"} {"GO.ID":"GO:0009123","Term":"nucleoside monophosphate metabolic process","Annotated":69,"Significant":6,"Expected":4.17,"Rank in p.value_classic":1998,"p.value_elim":0.23506,"p.value_classic":0.23681,"genes":"AK1,CMPK2,DPYS,TK1,TYMP,TYMS"} {"GO.ID":"GO:0060079","Term":"excitatory postsynaptic potential","Annotated":69,"Significant":6,"Expected":4.17,"Rank in p.value_classic":1999,"p.value_elim":0.23506,"p.value_classic":0.23681,"genes":"GHRL,LRRK2,P2RX4,P2RX7,STX1A,SYNE1"} {"GO.ID":"GO:0030855","Term":"epithelial cell differentiation","Annotated":495,"Significant":34,"Expected":29.9,"Rank in p.value_classic":2012,"p.value_elim":0.23522,"p.value_classic":0.23982,"genes":"AGR2,CDH5,CDK1,CEACAM1,CYP1A1,DAB2,DHRS9,DLL1,E2F8,EDN1,EPAS1,GSTK1,ICAM1,IL31RA,KLF4,LBH,MAF,MAFF,MARVELD2,MMP9,MTSS1,NRP1,ONECUT2,OVOL1,PLAAT3,PLAAT4,PRKX,RAPGEF2,S1PR1,SIDT2,SLC4A7,SOX17,STAT1,TYMS"} {"GO.ID":"GO:0003143","Term":"embryonic heart tube morphogenesis","Annotated":55,"Significant":5,"Expected":3.32,"Rank in p.value_classic":2001,"p.value_elim":0.23553,"p.value_classic":0.2371,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0001706","Term":"endoderm formation","Annotated":55,"Significant":5,"Expected":3.32,"Rank in p.value_classic":2002,"p.value_elim":0.23553,"p.value_classic":0.2371,"genes":"ITGA7,ITGB5,LAMB3,MMP9,SOX17"} {"GO.ID":"GO:0070498","Term":"interleukin-1-mediated signaling pathway","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2003,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"IL1RN,VRK2,ZBP1"} {"GO.ID":"GO:0038094","Term":"Fc-gamma receptor signaling pathway","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2004,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"APPL2,LYN,PLPP4"} {"GO.ID":"GO:1904037","Term":"positive regulation of epithelial cell apoptotic process","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2005,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"CD40,HLA-G,JAK2"} {"GO.ID":"GO:0044819","Term":"mitotic G1/S transition checkpoint signaling","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2006,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"GTSE1,MUC1,PML"} {"GO.ID":"GO:0031571","Term":"mitotic G1 DNA damage checkpoint signaling","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2007,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"GTSE1,MUC1,PML"} {"GO.ID":"GO:0006775","Term":"fat-soluble vitamin metabolic process","Annotated":28,"Significant":3,"Expected":1.69,"Rank in p.value_classic":2008,"p.value_elim":0.23648,"p.value_classic":0.23764,"genes":"AIFM2,CBR3,CYP1A1"} {"GO.ID":"GO:0090087","Term":"regulation of peptide transport","Annotated":142,"Significant":11,"Expected":8.58,"Rank in p.value_classic":2011,"p.value_elim":0.23664,"p.value_classic":0.23911,"genes":"CCL5,CD38,CD74,CRHBP,GHRL,HLA-DRB1,JAK2,LRP5,SIDT2,SRI,STX1A"} {"GO.ID":"GO:1903131","Term":"mononuclear cell differentiation","Annotated":401,"Significant":55,"Expected":24.22,"Rank in p.value_classic":147,"p.value_elim":0.2373,"p.value_classic":8.1e-09,"genes":"ADAM8,ASCL2,B2M,BATF2,BATF3,BCL6,BTN2A2,CD28,CD74,CD80,CD83,CSF1,CTLA4,CTSL,CYLD,DLL1,FGL2,GPR183,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK3,LAG3,LYN,MERTK,PTGER4,RELB,RIPK2,RSAD2,SLAMF1,SLAMF6,SLAMF8,SOCS1,TBX21,TMEM176A,TMEM176B,TNFSF13B,TNFSF8,TYRO3,UBD,VCAM1,ZC3H12A"} {"GO.ID":"GO:0001775","Term":"cell activation","Annotated":907,"Significant":119,"Expected":54.78,"Rank in p.value_classic":40,"p.value_elim":0.24014,"p.value_classic":1.7e-16,"genes":"ADAM8,ASCL2,B2M,BANK1,BATF2,BATF3,BCL6,BTN2A2,BTN3A1,CCL5,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CD93,CEACAM1,COMP,CSF1,CTLA4,CTSL,CX3CR1,CXADR,CXCL10,CYLD,DLL1,DYSF,EDN1,EXO1,F2RL3,FGL1,FGL2,GPR183,HAVCR1,HELLS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LRRK2,LYN,MERTK,NMI,NOD2,NR4A3,P2RX4,P2RX7,PARP3,PDCD1LG2,PLEK,PLSCR1,PSMB10,PTGER4,RELB,RIPK2,RSAD2,S100A13,SBNO2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,STAP1,SUCNR1,TBX21,THBD,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,UBD,UNG,VCAM1,ZC3H12A"} {"GO.ID":"GO:0050680","Term":"negative regulation of epithelial cell proliferation","Annotated":113,"Significant":9,"Expected":6.82,"Rank in p.value_classic":2013,"p.value_elim":0.24067,"p.value_classic":0.24291,"genes":"B2M,CEACAM1,DAB2,GHRL,IL12A,MIR503,MTSS1,OVOL1,STAT1"} {"GO.ID":"GO:1903531","Term":"negative regulation of secretion by cell","Annotated":113,"Significant":9,"Expected":6.82,"Rank in p.value_classic":2014,"p.value_elim":0.24067,"p.value_classic":0.24291,"genes":"ASIC1,CEACAM1,CRHBP,EDN1,GHRL,HLA-F,IL12A,OSM,RSAD2"} {"GO.ID":"GO:0015718","Term":"monocarboxylic acid transport","Annotated":110,"Significant":12,"Expected":6.64,"Rank in p.value_classic":1008,"p.value_elim":0.24246,"p.value_classic":0.03341,"genes":"ABCC11,ABCG2,ACSL1,ATP8B1,CEACAM1,EDN1,P2RX4,P2RX7,RBP7,SLC16A10,SLC6A12,TNFRSF11A"} {"GO.ID":"GO:0051101","Term":"regulation of DNA binding","Annotated":70,"Significant":6,"Expected":4.23,"Rank in p.value_classic":2024,"p.value_elim":0.24515,"p.value_classic":0.24695,"genes":"CDT1,E2F1,HJURP,JAK2,MMP9,PYHIN1"} {"GO.ID":"GO:0001676","Term":"long-chain fatty acid metabolic process","Annotated":70,"Significant":6,"Expected":4.23,"Rank in p.value_classic":2025,"p.value_elim":0.24515,"p.value_classic":0.24695,"genes":"ACOT4,ACSL1,CYP1A1,EPHX1,LTC4S,PNPLA3"} {"GO.ID":"GO:1900087","Term":"positive regulation of G1/S transition of mitotic cell cycle","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2017,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"CCNE2,CDC6,CYP1A1,RRM2"} {"GO.ID":"GO:0051972","Term":"regulation of telomerase activity","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2018,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"AURKB,KLF4,PARP3,PKIB"} {"GO.ID":"GO:0010883","Term":"regulation of lipid storage","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2019,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"C3,LPL,TTC39B,ZC3H12A"} {"GO.ID":"GO:0043154","Term":"negative regulation of cysteine-type endopeptidase activity involved in apoptotic process","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2020,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"CARD16,KLF4,LAMP3,MMP9"} {"GO.ID":"GO:1902305","Term":"regulation of sodium ion transmembrane transport","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2021,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"ATP1B2,CAMK2D,SCN4B,TESC"} {"GO.ID":"GO:2000772","Term":"regulation of cellular senescence","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2022,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"B2M,BCL6,GCH1,HLA-G"} {"GO.ID":"GO:0032506","Term":"cytokinetic process","Annotated":42,"Significant":4,"Expected":2.54,"Rank in p.value_classic":2023,"p.value_elim":0.24544,"p.value_classic":0.24685,"genes":"ANLN,AURKB,CHMP4C,IQGAP3"} {"GO.ID":"GO:0045069","Term":"regulation of viral genome replication","Annotated":81,"Significant":18,"Expected":4.89,"Rank in p.value_classic":230,"p.value_elim":0.24574,"p.value_classic":1.2e-06,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CD28,GBP7,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,OAS2,OAS3,PLSCR1,RSAD2,TOP2A,ZNFX1"} {"GO.ID":"GO:1901989","Term":"positive regulation of cell cycle phase transition","Annotated":99,"Significant":8,"Expected":5.98,"Rank in p.value_classic":2026,"p.value_elim":0.24599,"p.value_classic":0.2481,"genes":"CCNE2,CDC25A,CDC6,CDCA5,CDK1,CYP1A1,DTL,RRM2"} {"GO.ID":"GO:0035019","Term":"somatic stem cell population maintenance","Annotated":56,"Significant":5,"Expected":3.38,"Rank in p.value_classic":2027,"p.value_elim":0.24692,"p.value_classic":0.24854,"genes":"ASCL2,KLF4,LBH,LRP5,TAL1"} {"GO.ID":"GO:1903317","Term":"regulation of protein maturation","Annotated":56,"Significant":5,"Expected":3.38,"Rank in p.value_classic":2028,"p.value_elim":0.24692,"p.value_classic":0.24854,"genes":"ADAM8,CARD16,CHAC1,LRRK2,S100A10"} {"GO.ID":"GO:2000243","Term":"positive regulation of reproductive process","Annotated":56,"Significant":5,"Expected":3.38,"Rank in p.value_classic":2029,"p.value_elim":0.24692,"p.value_classic":0.24854,"genes":"CDC25A,DAZL,NPM2,OVOL1,PLB1"} {"GO.ID":"GO:1904705","Term":"regulation of vascular associated smooth muscle cell proliferation","Annotated":56,"Significant":5,"Expected":3.38,"Rank in p.value_classic":2030,"p.value_elim":0.24692,"p.value_classic":0.24854,"genes":"EDN1,JAK2,MIR503,MMP9,NR4A3"} {"GO.ID":"GO:0050688","Term":"regulation of defense response to virus","Annotated":58,"Significant":12,"Expected":3.5,"Rank in p.value_classic":375,"p.value_elim":0.24854,"p.value_classic":0.00015,"genes":"AIM2,APOBEC3G,DTX3L,FGL2,IL12RB1,IL15,IL27,PARP9,STAT1,TRIM22,TSPAN32,ZC3H12A"} {"GO.ID":"GO:0045862","Term":"positive regulation of proteolysis","Annotated":296,"Significant":21,"Expected":17.88,"Rank in p.value_classic":2062,"p.value_elim":0.24858,"p.value_classic":0.25223,"genes":"ADAM8,AIM2,CTSL,CTSS,DAB2,FAS,GRAMD4,JAK2,LRRK2,LYN,MEFV,NLRP12,NUB1,PMAIP1,PSME1,PSME2,PYHIN1,RIPK2,S100A10,TANK,TNFSF10"} {"GO.ID":"GO:0007159","Term":"leukocyte cell-cell adhesion","Annotated":342,"Significant":60,"Expected":20.66,"Rank in p.value_classic":61,"p.value_elim":0.24916,"p.value_classic":4.4e-14,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CTLA4,CX3CR1,CYLD,FGL1,FGL2,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,ICAM1,IDO1,IL12A,IL12RB1,IL15,IL4I1,IL7,IRF1,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LYN,NOD2,NR4A3,PDCD1LG2,RIPK2,SELL,SLAMF1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:0009148","Term":"pyrimidine nucleoside triphosphate biosynthetic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2031,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"CMPK2,TYMS"} {"GO.ID":"GO:0051957","Term":"positive regulation of amino acid transport","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2032,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DTNBP1,P2RX7"} {"GO.ID":"GO:1903978","Term":"regulation of microglial cell activation","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2033,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"LRRK2,STAP1"} {"GO.ID":"GO:0034349","Term":"glial cell apoptotic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2034,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DLL1,TNFRSF21"} {"GO.ID":"GO:0010885","Term":"regulation of cholesterol storage","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2035,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"LPL,TTC39B"} {"GO.ID":"GO:0010829","Term":"negative regulation of glucose transmembrane transport","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2036,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"APPL2,PID1"} {"GO.ID":"GO:0034114","Term":"regulation of heterotypic cell-cell adhesion","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2037,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"IL1RN,KLF4"} {"GO.ID":"GO:0033194","Term":"response to hydroperoxide","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2038,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"CD38,JAK2"} {"GO.ID":"GO:0034755","Term":"iron ion transmembrane transport","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2039,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"SLC11A1,SLC25A28"} {"GO.ID":"GO:1904355","Term":"positive regulation of telomere capping","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2040,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"AURKB,PKIB"} {"GO.ID":"GO:0071379","Term":"cellular response to prostaglandin stimulus","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2041,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"GNG2,PTGER4"} {"GO.ID":"GO:0048486","Term":"parasympathetic nervous system development","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2042,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"EGR2,NRP1"} {"GO.ID":"GO:0071318","Term":"cellular response to ATP","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2043,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"P2RX4,P2RX7"} {"GO.ID":"GO:0086066","Term":"atrial cardiac muscle cell to AV node cell communication","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2044,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"ANK2,KCNE5"} {"GO.ID":"GO:0086026","Term":"atrial cardiac muscle cell to AV node cell signaling","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2045,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"ANK2,KCNE5"} {"GO.ID":"GO:0086014","Term":"atrial cardiac muscle cell action potential","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2046,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"ANK2,KCNE5"} {"GO.ID":"GO:0071450","Term":"cellular response to oxygen radical","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2047,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0042759","Term":"long-chain fatty acid biosynthetic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2048,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"CYP1A1,LTC4S"} {"GO.ID":"GO:0071451","Term":"cellular response to superoxide","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2049,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0048268","Term":"clathrin coat assembly","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2050,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DAB2,DNM1"} {"GO.ID":"GO:0043517","Term":"positive regulation of DNA damage response, signal transduction by p53 class mediator","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2051,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"PMAIP1,PYHIN1"} {"GO.ID":"GO:0009070","Term":"serine family amino acid biosynthetic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2052,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DHFR,SERINC5"} {"GO.ID":"GO:0006266","Term":"DNA ligation","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2053,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"PARP3,TOP2A"} {"GO.ID":"GO:0090051","Term":"negative regulation of cell migration involved in sprouting angiogenesis","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2054,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"KLF4,MIR503"} {"GO.ID":"GO:0043949","Term":"regulation of cAMP-mediated signaling","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2055,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"PDE3B,RAPGEF2"} {"GO.ID":"GO:0045717","Term":"negative regulation of fatty acid biosynthetic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2056,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"BRCA1,CEACAM1"} {"GO.ID":"GO:0015874","Term":"norepinephrine transport","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2057,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"ADORA3,STX1A"} {"GO.ID":"GO:0061687","Term":"detoxification of inorganic compound","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2058,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"MT2A,SLC11A1"} {"GO.ID":"GO:0015812","Term":"gamma-aminobutyric acid transport","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2059,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"P2RX7,SLC6A12"} {"GO.ID":"GO:0019400","Term":"alditol metabolic process","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2060,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"DGAT2,GK"} {"GO.ID":"GO:0010460","Term":"positive regulation of heart rate","Annotated":16,"Significant":2,"Expected":0.97,"Rank in p.value_classic":2061,"p.value_elim":0.25039,"p.value_classic":0.25132,"genes":"EDN1,GCH1"} {"GO.ID":"GO:0070252","Term":"actin-mediated cell contraction","Annotated":85,"Significant":7,"Expected":5.13,"Rank in p.value_classic":2063,"p.value_elim":0.25099,"p.value_classic":0.25298,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,PDE4B,SCN4B,SRI"} {"GO.ID":"GO:0006304","Term":"DNA modification","Annotated":85,"Significant":7,"Expected":5.13,"Rank in p.value_classic":2064,"p.value_elim":0.25099,"p.value_classic":0.25298,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,HELLS,NEIL3,PARP3,UNG"} {"GO.ID":"GO:0045619","Term":"regulation of lymphocyte differentiation","Annotated":184,"Significant":30,"Expected":11.11,"Rank in p.value_classic":215,"p.value_elim":0.25271,"p.value_classic":5.7e-07,"genes":"ADAM8,ASCL2,BCL6,BTN2A2,CD28,CD74,CD80,CD83,CTLA4,CYLD,FGL2,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,JAK3,LAG3,RIPK2,SLAMF8,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:1902624","Term":"positive regulation of neutrophil migration","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2065,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"ADAM8,CD74,EDN1"} {"GO.ID":"GO:0060421","Term":"positive regulation of heart growth","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2066,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"CDK1,EDN1,PIM1"} {"GO.ID":"GO:0045933","Term":"positive regulation of muscle contraction","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2067,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"EDN1,GHRL,PROK2"} {"GO.ID":"GO:0070536","Term":"protein K63-linked deubiquitination","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2068,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"CYLD,OTUD1,STAMBPL1"} {"GO.ID":"GO:0030947","Term":"regulation of vascular endothelial growth factor receptor signaling pathway","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2069,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"DLL1,NRP1,VEGFC"} {"GO.ID":"GO:0051154","Term":"negative regulation of striated muscle cell differentiation","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2070,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"BHLHE41,DLL1,TMEM119"} {"GO.ID":"GO:0007129","Term":"homologous chromosome pairing at meiosis","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2071,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"CCNE2,DMC1,HORMAD1"} {"GO.ID":"GO:0048873","Term":"homeostasis of number of cells within a tissue","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2072,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"CSF1,IL7,P2RX7"} {"GO.ID":"GO:1902235","Term":"regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2073,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"BCL2L11,LRRK2,PMAIP1"} {"GO.ID":"GO:1901798","Term":"positive regulation of signal transduction by p53 class mediator","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2074,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"PMAIP1,PML,PYHIN1"} {"GO.ID":"GO:0035510","Term":"DNA dealkylation","Annotated":29,"Significant":3,"Expected":1.75,"Rank in p.value_classic":2075,"p.value_elim":0.25293,"p.value_classic":0.25414,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0044403","Term":"biological process involved in symbiotic interaction","Annotated":246,"Significant":33,"Expected":14.86,"Rank in p.value_classic":295,"p.value_elim":0.25314,"p.value_classic":0.00001,"genes":"APOL1,CCL5,CCL8,CD74,CD80,CDK1,CHMP4C,CIITA,CTSL,CX3CR1,CXADR,DYNLT1,FCN1,HAVCR1,HLA-DRB1,ICAM1,IFI27,IFITM1,IFITM2,IFITM3,IGF2R,ITGB5,NOD2,NRP1,PLSCR1,SLAMF1,TNFRSF14,TPCN1,TRIM22,TRIM31,TYRO3,WWP1,ZC3H12A"} {"GO.ID":"GO:0001944","Term":"vasculature development","Annotated":635,"Significant":49,"Expected":38.35,"Rank in p.value_classic":1080,"p.value_elim":0.25315,"p.value_classic":0.04517,"genes":"ADAM8,AMOT,ANTXR1,BRCA1,C3,CD40,CDH5,CEACAM1,COMP,CX3CR1,CXCL10,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDN1,EGR2,EPAS1,EPHB3,GHRL,GLUL,HLA-G,IL12A,KLF4,LRP5,MIR503,NPR1,NRCAM,NRP1,PDE3B,PLCD3,PML,PRKX,PROK2,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,STAT1,TAL1,THBS2,TNFAIP2,TYMP,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0033554","Term":"cellular response to stress","Annotated":1661,"Significant":112,"Expected":100.32,"Rank in p.value_classic":1440,"p.value_elim":0.25391,"p.value_classic":0.10992,"genes":"ADAM8,AGR2,AIFM2,AIM2,ARMT1,ATF3,ATP13A2,B2M,BACH1,BATF2,BATF3,BCL2A1,BCL2L11,BCL6,BRCA1,CASP4,CASTOR1,CCNA2,CD74,CDC45,CDCA5,CDK1,CHAC1,CHAF1B,CLSPN,COMP,CRHBP,CTLA4,CXCL10,CYSLTR1,DERL3,DHFR,DMC1,DTL,DTX3L,E2F1,EDN1,EEPD1,EME1,EPAS1,ESCO2,EXO1,FANCE,FAS,FBXO6,FEN1,GCH1,GINS2,GLUL,GTSE1,HGF,HLA-G,HSBP1L1,IL18BP,IRF7,JAK2,KLF4,KREMEN1,LRRK2,LYN,MAF,MAP1LC3C,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MMP9,MTSS1,MUC1,NCF1,NEIL3,NOD2,OPTN,PARP10,PARP3,PARP9,PCLAF,PDK4,PMAIP1,PML,POLB,POLE2,PXN,PYHIN1,RAD54B,RAD54L,RALB,RASGRF1,RECQL4,RELB,RMI2,RTN4RL1,SCARF1,SCIMP,SESN3,TANK,TFEC,TICRR,TIFAB,TMEM109,TNFRSF11A,TONSL,TOP2A,UBE2T,UHRF1,UNG,VRK2,WDR76,XRCC2,ZC3H12A"} {"GO.ID":"GO:0010632","Term":"regulation of epithelial cell migration","Annotated":205,"Significant":15,"Expected":12.38,"Rank in p.value_classic":2085,"p.value_elim":0.2542,"p.value_classic":0.25727,"genes":"AGT,CD40,CEACAM1,EDN1,ENPP2,GLIPR2,GLUL,HBEGF,KLF4,MIR503,MMP9,NRP1,P2RX4,VEGFC,ZC3H12A"} {"GO.ID":"GO:0010565","Term":"regulation of cellular ketone metabolic process","Annotated":100,"Significant":8,"Expected":6.04,"Rank in p.value_classic":2078,"p.value_elim":0.25451,"p.value_classic":0.25667,"genes":"APPL2,BRCA1,CD74,CEACAM1,DAB2,NR4A3,PDK4,SLC45A3"} {"GO.ID":"GO:0043149","Term":"stress fiber assembly","Annotated":100,"Significant":8,"Expected":6.04,"Rank in p.value_classic":2079,"p.value_elim":0.25451,"p.value_classic":0.25667,"genes":"ITGB5,NRP1,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0030038","Term":"contractile actin filament bundle assembly","Annotated":100,"Significant":8,"Expected":6.04,"Rank in p.value_classic":2080,"p.value_elim":0.25451,"p.value_classic":0.25667,"genes":"ITGB5,NRP1,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0046887","Term":"positive regulation of hormone secretion","Annotated":100,"Significant":8,"Expected":6.04,"Rank in p.value_classic":2081,"p.value_elim":0.25451,"p.value_classic":0.25667,"genes":"CD38,DAB2,EDN1,GHRL,HCAR2,HLA-DRB1,JAK2,SRI"} {"GO.ID":"GO:0046683","Term":"response to organophosphorus","Annotated":100,"Significant":8,"Expected":6.04,"Rank in p.value_classic":2082,"p.value_elim":0.25451,"p.value_classic":0.25667,"genes":"CRHBP,P2RX4,P2RX7,RAPGEF2,STAT1,THBD,TLR7,TYMS"} {"GO.ID":"GO:1903035","Term":"negative regulation of response to wounding","Annotated":71,"Significant":6,"Expected":4.29,"Rank in p.value_classic":2083,"p.value_elim":0.25537,"p.value_classic":0.25721,"genes":"CEACAM1,EDN1,KREMEN1,RTN4RL1,SERPING1,THBD"} {"GO.ID":"GO:0030218","Term":"erythrocyte differentiation","Annotated":115,"Significant":9,"Expected":6.95,"Rank in p.value_classic":2086,"p.value_elim":0.2565,"p.value_classic":0.25882,"genes":"ALAS1,B2M,BCL6,EPAS1,JAK2,LYN,NCAPG2,STAT1,TAL1"} {"GO.ID":"GO:0045931","Term":"positive regulation of mitotic cell cycle","Annotated":115,"Significant":9,"Expected":6.95,"Rank in p.value_classic":2087,"p.value_elim":0.2565,"p.value_classic":0.25882,"genes":"CCNE2,CDC25A,CDC6,CDCA5,CDK1,CYP1A1,DTL,RRM2,TAL1"} {"GO.ID":"GO:0043583","Term":"ear development","Annotated":160,"Significant":12,"Expected":9.66,"Rank in p.value_classic":2088,"p.value_elim":0.2573,"p.value_classic":0.26003,"genes":"ATP8B1,BCL2L11,C1QTNF5,CCNA2,DLL1,EDN1,HESX1,MAF,MCM2,SLC4A7,SOBP,TIFAB"} {"GO.ID":"GO:0007623","Term":"circadian rhythm","Annotated":160,"Significant":12,"Expected":9.66,"Rank in p.value_classic":2089,"p.value_elim":0.2573,"p.value_classic":0.26003,"genes":"ATF5,BHLHE41,BMAL2,C3orf70,CDK1,GHRL,PML,PROK2,RELB,TNFRSF11A,TOP2A,TYMS"} {"GO.ID":"GO:0045621","Term":"positive regulation of lymphocyte differentiation","Annotated":118,"Significant":17,"Expected":7.13,"Rank in p.value_classic":474,"p.value_elim":0.25794,"p.value_classic":0.00071,"genes":"ADAM8,BCL6,BTN2A2,CD74,CD80,CD83,CYLD,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL4I1,IL7,RIPK2,SOCS1"} {"GO.ID":"GO:0034762","Term":"regulation of transmembrane transport","Annotated":339,"Significant":32,"Expected":20.47,"Rank in p.value_classic":713,"p.value_elim":0.25808,"p.value_classic":0.00808,"genes":"ABCB1,ACSL1,ANK2,APPL2,ATP1B2,C3,CAMK2D,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MMP9,NR4A3,P2RX4,P2RX7,PDE4B,PID1,PIM1,PML,SCN4B,SLC31A2,SRI,TESC,TRDN"} {"GO.ID":"GO:0008202","Term":"steroid metabolic process","Annotated":221,"Significant":16,"Expected":13.35,"Rank in p.value_classic":2098,"p.value_elim":0.25844,"p.value_classic":0.26165,"genes":"APOL1,APOL2,ATP8B1,CYP1A1,DAB2,DHRS9,FAXDC2,G6PC1,HSD11B1,HSD3B7,LRP5,OSBPL6,SCARF1,SGPL1,SOAT1,TTC39B"} {"GO.ID":"GO:0043525","Term":"positive regulation of neuron apoptotic process","Annotated":57,"Significant":5,"Expected":3.44,"Rank in p.value_classic":2090,"p.value_elim":0.25846,"p.value_classic":0.26012,"genes":"BCL2L11,CASP4,CASP7,GCH1,MYBL2"} {"GO.ID":"GO:0009605","Term":"response to external stimulus","Annotated":2047,"Significant":245,"Expected":123.63,"Rank in p.value_classic":15,"p.value_elim":0.25848,"p.value_classic":3.4e-29,"genes":"ACOD1,ACSL1,ADAM8,AGT,AIM2,AMOT,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,ATF3,AURKB,B2M,BANK1,BATF2,BATF3,BCL6,BMAL2,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD274,CD28,CD300H,CD300LF,CD40,CD74,CD80,CDH5,CDS1,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,CMPK2,COLEC12,CSF1,CSF2RB,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DDX60,DTX3L,EDN1,ENPP2,ENPP4,FAM107A,FAM20A,FAS,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GHRL,GLUL,GPR183,GPR31,GRAMD4,GRIN3A,GSDMA,GSDMD,H2BC21,HBEGF,HGF,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSD3B7,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL22RA2,IL27,IL31RA,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KARS1,KCNJ2,KIF26A,KLF4,KLRK1,KREMEN1,LAG3,LILRA2,LITAF,LPL,LRRK2,LTA,LYN,MAP1LC3C,MCOLN2,MEFV,MMP9,MSRB1,MTUS1,NCF1,NLRC5,NLRP12,NMI,NOD2,NRP1,NUB1,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP9,PDCD1LG2,PDE4B,PDK4,PIM1,PKD1L3,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PML,PPM1E,PROK2,PTGER4,PYHIN1,RAB20,RALB,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTN4RL1,RTP4,S1PR1,SBNO2,SCARF1,SCIMP,SEMA6B,SERINC5,SERPING1,SESN3,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SSTR2,STAP1,STAT1,STAT2,STMN1,SUCNR1,TANK,TAP2,TBX21,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM255A,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF8,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN32,TYMP,TYMS,TYRO3,UBD,UBE2L6,USP53,VCAM1,VEGFC,VWCE,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0038084","Term":"vascular endothelial growth factor signaling pathway","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2091,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"DLL1,IL12A,NRP1,VEGFC"} {"GO.ID":"GO:0061028","Term":"establishment of endothelial barrier","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2092,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"CDH5,ICAM1,MARVELD2,RAPGEF2"} {"GO.ID":"GO:0002269","Term":"leukocyte activation involved in inflammatory response","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2093,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"CX3CR1,JAK2,LRRK2,STAP1"} {"GO.ID":"GO:0042771","Term":"intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2094,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"CD74,MUC1,PML,TMEM109"} {"GO.ID":"GO:0071526","Term":"semaphorin-plexin signaling pathway","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2095,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"EDN1,NRP1,PLXNA2,SEMA6B"} {"GO.ID":"GO:1904645","Term":"response to amyloid-beta","Annotated":43,"Significant":4,"Expected":2.6,"Rank in p.value_classic":2096,"p.value_elim":0.25886,"p.value_classic":0.26032,"genes":"CASP4,ICAM1,MMP9,VCAM1"} {"GO.ID":"GO:0050863","Term":"regulation of T cell activation","Annotated":319,"Significant":60,"Expected":19.27,"Rank in p.value_classic":46,"p.value_elim":0.25977,"p.value_classic":1.7e-15,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CTLA4,CYLD,FGL1,FGL2,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,IRF4,JAK2,JAK3,KITLG,KLRK1,LAG3,LYN,NOD2,PDCD1LG2,RIPK2,SIT1,SLAMF1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:1901655","Term":"cellular response to ketone","Annotated":86,"Significant":7,"Expected":5.19,"Rank in p.value_classic":2099,"p.value_elim":0.26031,"p.value_classic":0.26235,"genes":"ACOD1,GNG2,JAK2,KLF4,NCF1,PTGER4,XRN1"} {"GO.ID":"GO:0048534","Term":"hematopoietic or lymphoid organ development","Annotated":86,"Significant":7,"Expected":5.19,"Rank in p.value_classic":2100,"p.value_elim":0.26031,"p.value_classic":0.26235,"genes":"BCL2L11,EPHB3,IL15,LRP5,LTA,POLB,TNFRSF11A"} {"GO.ID":"GO:0051054","Term":"positive regulation of DNA metabolic process","Annotated":283,"Significant":20,"Expected":17.09,"Rank in p.value_classic":2101,"p.value_elim":0.26076,"p.value_classic":0.2644,"genes":"AURKB,BAZ1A,BRCA1,CCNA2,CD28,CDC25A,CDK1,CDT1,CHTF18,DSCC1,E2F8,GCH1,HGF,KLF4,NPM2,PARP3,PKIB,PML,TBX21,WEE1"} {"GO.ID":"GO:0044703","Term":"multi-organism reproductive process","Annotated":143,"Significant":14,"Expected":8.64,"Rank in p.value_classic":1118,"p.value_elim":0.26089,"p.value_classic":0.05035,"genes":"ACOD1,APOL2,CD38,CLIC5,CRHBP,CYP1A1,EDN1,GHRL,IDO1,MAFF,MMP9,PZP,RXFP1,THBD"} {"GO.ID":"GO:0048646","Term":"anatomical structure formation involved in morphogenesis","Annotated":958,"Significant":69,"Expected":57.86,"Rank in p.value_classic":1247,"p.value_elim":0.26096,"p.value_classic":0.06952,"genes":"ADAM8,ADAMTS15,AMOT,ANK2,ATP8B1,BCL2L11,BCL6,BRCA1,C3,CD40,CDH5,CEACAM1,CELSR1,CX3CR1,CXCL10,CXCL9,CXCR3,CYSLTR1,DLL1,E2F2,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,FAM20A,GHRL,GLUL,HESX1,HLA-G,IFT122,IL12A,ITGA7,ITGB5,KLF4,LAMB3,MIR503,MMP9,MYOZ2,NPR1,NRCAM,NRP1,PDE3B,PIM1,PLCD3,PLXNA2,PML,PRKX,PROK2,RNF213,S1PR1,SAT1,SBNO2,SH3PXD2A,SOX17,SSBP3,STAT1,TAL1,TGM2,THBS2,TIFAB,TNFAIP2,TNFSF13B,TYMP,VEGFC,WARS1,XRCC2,ZC3H12A"} {"GO.ID":"GO:2000026","Term":"regulation of multicellular organismal development","Annotated":1164,"Significant":104,"Expected":70.3,"Rank in p.value_classic":317,"p.value_elim":0.26136,"p.value_classic":0.00002,"genes":"ADAM8,AMOT,ANKH,APPL2,ASCL2,B2M,BCL6,BHLHE41,BRCA1,BTN2A2,C3,CD101,CD28,CD40,CD74,CD80,CD83,CDH5,CDK1,CEACAM1,COMP,CSF1,CTLA4,CX3CR1,CXCL10,CYLD,CYSLTR1,DAB1,DLL1,DYNLT1,E2F2,EDN1,EGR2,EPHB3,FAXDC2,FGL2,FSTL4,GHRL,GLUL,HAPLN3,HESX1,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,IRF7,JAK3,KITLG,KLF4,LAG3,LILRB3,LTA,LYN,MAF,MAFF,MIR503,MMP9,NPR1,NRP1,OAS2,P2RX7,PDE3B,PIM1,PLAAT4,PLXNA2,PML,PRKX,RAPGEF2,RIPK2,S100A10,S1PR1,SCIN,SEMA6B,SLAMF8,SOCS1,SOX17,STAT1,TAL1,TBX21,TESC,TGM2,THBS2,TMEM119,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF21,TYMP,VCAN,VEGFC,WARS1,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0030029","Term":"actin filament-based process","Annotated":693,"Significant":46,"Expected":41.85,"Rank in p.value_classic":2108,"p.value_elim":0.26474,"p.value_classic":0.27054,"genes":"AMOT,ANK2,ANLN,ANTXR1,ASB2,BCL6,CAMK2D,CELSR1,CXADR,DTNBP1,EDN1,FAM107A,FGD5,FMNL2,FRMD3,FSCN1,GHRL,IQGAP3,ITGB5,JAK2,KCNE5,KCNJ2,LIMK2,MARCKSL1,MICAL2,MRAS,MSRB1,MTSS1,MYO7B,MYOZ2,NRP1,PDE4B,PLEK,PPM1E,PSTPIP2,PTGER4,PXN,S100A10,S1PR1,SCIN,SCN4B,SPTBN4,SRI,STMN1,TMSB10,XIRP1"} {"GO.ID":"GO:0032647","Term":"regulation of interferon-alpha production","Annotated":27,"Significant":7,"Expected":1.63,"Rank in p.value_classic":479,"p.value_elim":0.26568,"p.value_classic":0.00087,"genes":"IFIH1,IRF7,NMI,RIPK2,STAT1,TLR7,TLR8"} {"GO.ID":"GO:0032607","Term":"interferon-alpha production","Annotated":27,"Significant":7,"Expected":1.63,"Rank in p.value_classic":480,"p.value_elim":0.26568,"p.value_classic":0.00087,"genes":"IFIH1,IRF7,NMI,RIPK2,STAT1,TLR7,TLR8"} {"GO.ID":"GO:0050848","Term":"regulation of calcium-mediated signaling","Annotated":72,"Significant":6,"Expected":4.35,"Rank in p.value_classic":2102,"p.value_elim":0.26569,"p.value_classic":0.26758,"genes":"EDN1,GBP1,LRRK2,MYOZ2,P2RX4,PLEK"} {"GO.ID":"GO:0021675","Term":"nerve development","Annotated":72,"Significant":6,"Expected":4.35,"Rank in p.value_classic":2103,"p.value_elim":0.26569,"p.value_classic":0.26758,"genes":"ATP8B1,EDN1,EGR2,NRP1,TIFAB,VCAM1"} {"GO.ID":"GO:0030330","Term":"DNA damage response, signal transduction by p53 class mediator","Annotated":72,"Significant":6,"Expected":4.35,"Rank in p.value_classic":2104,"p.value_elim":0.26569,"p.value_classic":0.26758,"genes":"CD74,GTSE1,MUC1,PMAIP1,PML,PYHIN1"} {"GO.ID":"GO:0090713","Term":"immunological memory process","Annotated":15,"Significant":6,"Expected":0.91,"Rank in p.value_classic":376,"p.value_elim":0.26577,"p.value_classic":0.00015,"genes":"BCL6,FGL2,HLA-DRA,HLA-DRB1,IL12RB1,TNFRSF14"} {"GO.ID":"GO:0031669","Term":"cellular response to nutrient levels","Annotated":207,"Significant":15,"Expected":12.5,"Rank in p.value_classic":2105,"p.value_elim":0.26613,"p.value_classic":0.26928,"genes":"ATF3,CASTOR1,FAM107A,FAS,GLUL,LPL,LRRK2,MAP1LC3C,PDK4,PIM1,PMAIP1,RALB,SESN3,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0002902","Term":"regulation of B cell apoptotic process","Annotated":19,"Significant":5,"Expected":1.15,"Rank in p.value_classic":647,"p.value_elim":0.26614,"p.value_classic":0.00453,"genes":"AURKB,BCL6,CD74,LYN,PDCD1"} {"GO.ID":"GO:1901976","Term":"regulation of cell cycle checkpoint","Annotated":42,"Significant":7,"Expected":2.54,"Rank in p.value_classic":784,"p.value_elim":0.26746,"p.value_classic":0.01208,"genes":"AURKB,BIRC5,BRCA1,MAD2L1,NDC80,WDR76,ZWINT"} {"GO.ID":"GO:0042113","Term":"B cell activation","Annotated":228,"Significant":23,"Expected":13.77,"Rank in p.value_classic":763,"p.value_elim":0.26772,"p.value_classic":0.01088,"genes":"BANK1,BCL6,CD28,CD38,CD40,CD74,CTLA4,CYLD,DLL1,EXO1,GPR183,IL4I1,IL7,JAK3,LYN,NOD2,PARP3,SLAMF8,TBX21,TNFRSF21,TNFSF13B,UNG,VCAM1"} {"GO.ID":"GO:0051402","Term":"neuron apoptotic process","Annotated":238,"Significant":17,"Expected":14.37,"Rank in p.value_classic":2119,"p.value_elim":0.26776,"p.value_classic":0.27115,"genes":"ADAM8,ATP13A2,BCL2L11,CASP4,CASP7,CX3CR1,FAS,GCH1,JAK2,MYBL2,NRP1,PCDHGC3,POLB,TNFRSF21,TYRO3,USP53,XRCC2"} {"GO.ID":"GO:0002688","Term":"regulation of leukocyte chemotaxis","Annotated":101,"Significant":18,"Expected":6.1,"Rank in p.value_classic":323,"p.value_elim":0.26785,"p.value_classic":0.00003,"genes":"CCL5,CCL7,CD74,CSF1,CX3CR1,CXCL10,EDN1,IL12A,KLRK1,LYN,MTUS1,NOD2,PADI2,SLAMF1,SLAMF8,STAP1,TNFAIP6,VEGFC"} {"GO.ID":"GO:0050920","Term":"regulation of chemotaxis","Annotated":187,"Significant":24,"Expected":11.29,"Rank in p.value_classic":428,"p.value_elim":0.26805,"p.value_classic":0.00038,"genes":"CCL5,CCL7,CD74,CSF1,CX3CR1,CXCL10,EDN1,GPR183,IL12A,KLRK1,LYN,MTUS1,NOD2,NRP1,P2RX4,PADI2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,SUCNR1,TNFAIP6,VEGFC"} {"GO.ID":"GO:0001822","Term":"kidney development","Annotated":269,"Significant":19,"Expected":16.25,"Rank in p.value_classic":2126,"p.value_elim":0.26839,"p.value_classic":0.272,"genes":"AGT,AMER1,BCL2L11,CENPF,CTNS,DLL1,EDN1,GCNT3,HELLS,LRRK2,MMP9,MTSS1,NRP1,OVOL1,PKD1L3,PRKX,SGPL1,SOX17,STAT1"} {"GO.ID":"GO:0150077","Term":"regulation of neuroinflammatory response","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2109,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"LRRK2,MMP9,STAP1"} {"GO.ID":"GO:0009112","Term":"nucleobase metabolic process","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2110,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"DPYS,TYMP,TYMS"} {"GO.ID":"GO:0034389","Term":"lipid droplet organization","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2111,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"CDS1,PNPLA3,RNF213"} {"GO.ID":"GO:1900225","Term":"regulation of NLRP3 inflammasome complex assembly","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2112,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"GBP5,MEFV,TRIM31"} {"GO.ID":"GO:0008340","Term":"determination of adult lifespan","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2113,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"LRRK2,RAD54B,RAD54L"} {"GO.ID":"GO:0071459","Term":"protein localization to chromosome, centromeric region","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2114,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"AURKB,BUB1B,CDK1"} {"GO.ID":"GO:0017158","Term":"regulation of calcium ion-dependent exocytosis","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2115,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"STX1A,SYT1,SYT6"} {"GO.ID":"GO:0007212","Term":"dopamine receptor signaling pathway","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2116,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"DTNBP1,GNG2,LRRK2"} {"GO.ID":"GO:1902751","Term":"positive regulation of cell cycle G2/M phase transition","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2117,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"CDC25A,CDK1,DTL"} {"GO.ID":"GO:0046688","Term":"response to copper ion","Annotated":30,"Significant":3,"Expected":1.81,"Rank in p.value_classic":2118,"p.value_elim":0.26952,"p.value_classic":0.27079,"genes":"CDK1,CYP1A1,MT2A"} {"GO.ID":"GO:0022406","Term":"membrane docking","Annotated":87,"Significant":7,"Expected":5.25,"Rank in p.value_classic":2120,"p.value_elim":0.26973,"p.value_classic":0.27181,"genes":"ICAM1,PLEK,RALB,STX11,STX1A,SYT1,VCAM1"} {"GO.ID":"GO:0038034","Term":"signal transduction in absence of ligand","Annotated":58,"Significant":5,"Expected":3.5,"Rank in p.value_classic":2121,"p.value_elim":0.27011,"p.value_classic":0.27183,"genes":"BCL2A1,BCL2L11,FAS,IL7,KITLG"} {"GO.ID":"GO:1990874","Term":"vascular associated smooth muscle cell proliferation","Annotated":58,"Significant":5,"Expected":3.5,"Rank in p.value_classic":2122,"p.value_elim":0.27011,"p.value_classic":0.27183,"genes":"EDN1,JAK2,MIR503,MMP9,NR4A3"} {"GO.ID":"GO:0097192","Term":"extrinsic apoptotic signaling pathway in absence of ligand","Annotated":58,"Significant":5,"Expected":3.5,"Rank in p.value_classic":2123,"p.value_elim":0.27011,"p.value_classic":0.27183,"genes":"BCL2A1,BCL2L11,FAS,IL7,KITLG"} {"GO.ID":"GO:0006879","Term":"intracellular iron ion homeostasis","Annotated":58,"Significant":5,"Expected":3.5,"Rank in p.value_classic":2124,"p.value_elim":0.27011,"p.value_classic":0.27183,"genes":"ATP13A2,B2M,SLC11A1,SRI,STEAP4"} {"GO.ID":"GO:0002931","Term":"response to ischemia","Annotated":58,"Significant":5,"Expected":3.5,"Rank in p.value_classic":2125,"p.value_elim":0.27011,"p.value_classic":0.27183,"genes":"CSF1,CX3CR1,GPR31,P2RX4,P2RX7"} {"GO.ID":"GO:0032648","Term":"regulation of interferon-beta production","Annotated":56,"Significant":10,"Expected":3.38,"Rank in p.value_classic":537,"p.value_elim":0.27048,"p.value_classic":0.00172,"genes":"IFIH1,IRF1,IRF7,NMI,OAS2,OAS3,RELB,RIPK2,TLR7,TLR8"} {"GO.ID":"GO:0032608","Term":"interferon-beta production","Annotated":56,"Significant":10,"Expected":3.38,"Rank in p.value_classic":538,"p.value_elim":0.27048,"p.value_classic":0.00172,"genes":"IFIH1,IRF1,IRF7,NMI,OAS2,OAS3,RELB,RIPK2,TLR7,TLR8"} {"GO.ID":"GO:0071310","Term":"cellular response to organic substance","Annotated":1589,"Significant":169,"Expected":95.97,"Rank in p.value_classic":58,"p.value_elim":0.27107,"p.value_classic":2.5e-14,"genes":"ACOD1,ACSL1,AGR2,AGT,AIM2,APPL2,ATF3,BCL2L11,BRCA1,CARD16,CASP4,CASP7,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD274,CD300LF,CD40,CD74,CD80,CDC6,CDK1,CEACAM1,CMPK2,COLEC12,CRHBP,CSF1,CSF2RB,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,DAB2,DERL3,DGAT2,DTNBP1,EDN1,EGR2,FAM107A,FAS,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GHRL,GNG2,GRAMD1B,HELLS,HLA-DPA1,HLA-DRB1,ICAM1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IQGAP3,IRF1,IRF7,JAK2,JAK3,KLF4,KLRK1,LBH,LILRA1,LILRA2,LITAF,LPL,LRP5,LRRK2,LYN,MCM2,MMP9,MRAS,MT2A,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLSCR4,PML,PNPLA3,PPM1E,PTGER4,PXN,PYHIN1,RAB20,RALB,RAPGEF2,RIPK2,RUFY4,RXFP1,SBNO2,SCIMP,SESN3,SIDT2,SLC2A5,SNX10,SOCS1,SOX17,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,TANK,TBX21,TESC,TGM2,TICAM2,TIFA,TIFAB,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,VEGFC,VRK2,XRN1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0009595","Term":"detection of biotic stimulus","Annotated":30,"Significant":6,"Expected":1.81,"Rank in p.value_classic":715,"p.value_elim":0.27168,"p.value_classic":0.00812,"genes":"C4B,CLEC6A,HLA-A,HLA-B,HLA-DRB1,NOD2"} {"GO.ID":"GO:0001824","Term":"blastocyst development","Annotated":102,"Significant":8,"Expected":6.16,"Rank in p.value_classic":2133,"p.value_elim":0.27182,"p.value_classic":0.27407,"genes":"GINS1,HORMAD1,KLF4,NCAPG2,NPM2,PLPP4,RRM2,SOX17"} {"GO.ID":"GO:0045668","Term":"negative regulation of osteoblast differentiation","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2127,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"CHRD,LRP5,TNFAIP6,VEGFC"} {"GO.ID":"GO:0098900","Term":"regulation of action potential","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2128,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"ANK2,CAMK2D,CXADR,KCNJ2"} {"GO.ID":"GO:0044788","Term":"modulation by host of viral process","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2129,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"CCL8,IFI27,IGF2R,ZC3H12A"} {"GO.ID":"GO:0009994","Term":"oocyte differentiation","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2130,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"DAZL,DMC1,EDN1,NPM2"} {"GO.ID":"GO:0086002","Term":"cardiac muscle cell action potential involved in contraction","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2131,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"ANK2,KCNE5,KCNJ2,SCN4B"} {"GO.ID":"GO:0006284","Term":"base-excision repair","Annotated":44,"Significant":4,"Expected":2.66,"Rank in p.value_classic":2132,"p.value_elim":0.27242,"p.value_classic":0.27393,"genes":"FEN1,NEIL3,POLB,UNG"} {"GO.ID":"GO:0043269","Term":"regulation of monoatomic ion transport","Annotated":326,"Significant":31,"Expected":19.69,"Rank in p.value_classic":724,"p.value_elim":0.27242,"p.value_classic":0.00817,"genes":"ABCB1,ANK2,ATP1B2,ATP8B1,B2M,CAMK2D,CCL5,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PLPP4,PML,SCN4B,SLC31A2,SPTBN4,SRI,TESC,TRDN"} {"GO.ID":"GO:0007098","Term":"centrosome cycle","Annotated":132,"Significant":10,"Expected":7.97,"Rank in p.value_classic":2159,"p.value_elim":0.27262,"p.value_classic":0.27517,"genes":"ATF5,BRCA1,CCNF,CDK1,CHMP4C,KIF11,NDC80,PCLAF,WDR62,XRCC2"} {"GO.ID":"GO:0061351","Term":"neural precursor cell proliferation","Annotated":132,"Significant":10,"Expected":7.97,"Rank in p.value_classic":2160,"p.value_elim":0.27262,"p.value_classic":0.27517,"genes":"APPL2,ATF5,CX3CR1,HAPLN3,LRRK2,LYN,SHCBP1,VCAN,VEGFC,WDR62"} {"GO.ID":"GO:0007565","Term":"female pregnancy","Annotated":132,"Significant":10,"Expected":7.97,"Rank in p.value_classic":2161,"p.value_elim":0.27262,"p.value_classic":0.27517,"genes":"ACOD1,APOL2,CD38,CLIC5,CRHBP,GHRL,IDO1,MMP9,PZP,THBD"} {"GO.ID":"GO:2001224","Term":"positive regulation of neuron migration","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2134,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"RAPGEF2,WDR62"} {"GO.ID":"GO:0051900","Term":"regulation of mitochondrial depolarization","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2135,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"LRRK2,P2RX7"} {"GO.ID":"GO:0003081","Term":"regulation of systemic arterial blood pressure by renin-angiotensin","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2136,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"AGT,SUCNR1"} {"GO.ID":"GO:0003071","Term":"renal system process involved in regulation of systemic arterial blood pressure","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2137,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"AGT,SUCNR1"} {"GO.ID":"GO:0070431","Term":"nucleotide-binding oligomerization domain containing 2 signaling pathway","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2138,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"NOD2,RIPK2"} {"GO.ID":"GO:1901970","Term":"positive regulation of mitotic sister chromatid separation","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2139,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"AURKB,BIRC5"} {"GO.ID":"GO:0030540","Term":"female genitalia development","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2140,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"MERTK,TYRO3"} {"GO.ID":"GO:0016082","Term":"synaptic vesicle priming","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2141,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ERC2,STX1A"} {"GO.ID":"GO:0042178","Term":"xenobiotic catabolic process","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2142,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ACSL1,CYP1A1"} {"GO.ID":"GO:0051382","Term":"kinetochore assembly","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2143,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"CENPF,CENPK"} {"GO.ID":"GO:0042219","Term":"cellular modified amino acid catabolic process","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2144,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"CHAC1,GGT5"} {"GO.ID":"GO:0086013","Term":"membrane repolarization during cardiac muscle cell action potential","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2145,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"KCNE5,KCNJ2"} {"GO.ID":"GO:0071467","Term":"cellular response to pH","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2146,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ASIC1,PKD1L3"} {"GO.ID":"GO:2000269","Term":"regulation of fibroblast apoptotic process","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2147,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"BCL2L11,XRCC2"} {"GO.ID":"GO:0061436","Term":"establishment of skin barrier","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2148,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"KLF4,STMN1"} {"GO.ID":"GO:0032874","Term":"positive regulation of stress-activated MAPK cascade","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2149,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"NOD2,SCIMP"} {"GO.ID":"GO:1902307","Term":"positive regulation of sodium ion transmembrane transport","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2150,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ATP1B2,TESC"} {"GO.ID":"GO:0050999","Term":"regulation of nitric-oxide synthase activity","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2151,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"DHFR,GCH1"} {"GO.ID":"GO:1902165","Term":"regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2152,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"CD74,MUC1"} {"GO.ID":"GO:0046128","Term":"purine ribonucleoside metabolic process","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2153,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ENPP4,PRTFDC1"} {"GO.ID":"GO:1904862","Term":"inhibitory synapse assembly","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2154,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"GABRA3,LGI2"} {"GO.ID":"GO:0051546","Term":"keratinocyte migration","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2155,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"HBEGF,MMP9"} {"GO.ID":"GO:0045780","Term":"positive regulation of bone resorption","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2156,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"ADAM8,TNFRSF11A"} {"GO.ID":"GO:1901739","Term":"regulation of myoblast fusion","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2157,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"CXCL10,CXCL9"} {"GO.ID":"GO:0019184","Term":"nonribosomal peptide biosynthetic process","Annotated":17,"Significant":2,"Expected":1.03,"Rank in p.value_classic":2158,"p.value_elim":0.27327,"p.value_classic":0.27426,"genes":"CHAC1,GGT5"} {"GO.ID":"GO:0007276","Term":"gamete generation","Annotated":521,"Significant":35,"Expected":31.47,"Rank in p.value_classic":2164,"p.value_elim":0.2737,"p.value_classic":0.27879,"genes":"ADGB,BCL2L11,BCL6,CXADR,DAZL,DMC1,EDN1,HORMAD1,IGF2R,LIMK2,LRRK2,MEIKIN,MERTK,NCAPH,NDC80,NPM2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PROK2,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TMEM119,TNFAIP6,TOP2A,TYRO3,ZMYND15"} {"GO.ID":"GO:0006690","Term":"icosanoid metabolic process","Annotated":73,"Significant":6,"Expected":4.41,"Rank in p.value_classic":2162,"p.value_elim":0.27612,"p.value_classic":0.27805,"genes":"CD74,CYP1A1,EDN1,EPHX1,GGT5,LTC4S"} {"GO.ID":"GO:0007492","Term":"endoderm development","Annotated":73,"Significant":6,"Expected":4.41,"Rank in p.value_classic":2163,"p.value_elim":0.27612,"p.value_classic":0.27805,"genes":"ITGA7,ITGB5,LAMB3,MMP9,SOX17,SSBP3"} {"GO.ID":"GO:0097193","Term":"intrinsic apoptotic signaling pathway","Annotated":286,"Significant":20,"Expected":17.27,"Rank in p.value_classic":2166,"p.value_elim":0.27617,"p.value_classic":0.27994,"genes":"BCL2A1,BCL2L11,BRCA1,CASP4,CD74,CHAC1,CYLD,E2F1,E2F2,HELLS,JAK2,LRRK2,MMP9,MUC1,PMAIP1,PML,POLB,SEPTIN4,TIFAB,TMEM109"} {"GO.ID":"GO:0032501","Term":"multicellular organismal process","Annotated":5376,"Significant":409,"Expected":324.69,"Rank in p.value_classic":114,"p.value_elim":0.27668,"p.value_classic":2.9e-10,"genes":"AATK,ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,ADGB,ADORA3,AGR2,AGT,AIM2,ALAS1,AMER1,AMOT,ANK2,ANKH,ANLN,ANTXR1,APOL2,APPL2,ASB2,ASCL2,ASIC1,ATF5,ATP1B2,ATP8B1,AURKB,B2M,BANK1,BATF2,BATF3,BCL2L11,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C21orf91,C3,C3orf70,CAMK2D,CARD16,CASP7,CASZ1,CBR3,CCL5,CD101,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CD93,CDH5,CDK1,CDKN2C,CEACAM1,CELSR1,CENPF,CENPU,CHAC1,CHMP4C,CHRD,CIBAR1,CLEC6A,CLEC9A,CLIC5,COL9A2,COLQ,COMP,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CX3CR1,CXADR,CXCL10,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DGAT2,DHFR,DHRS3,DLGAP3,DLL1,DMC1,DNAAF1,DTNBP1,DYNLT1,DYSF,E2F1,E2F2,E2F8,ECEL1,EDA,EDN1,EGR2,ENPP2,ENPP4,EPAS1,EPHB3,EPOP,ERAP2,EXO1,F2RL3,FAM107A,FAS,FAXDC2,FCN1,FEN1,FGL1,FGL2,FLT3LG,FSTL4,G0S2,G6PC1,GABRA3,GBP1,GBP5,GBP7,GCH1,GCNT3,GFRA2,GHRL,GINS1,GJD3,GLDN,GLIPR2,GLUL,GPR183,GRIN3A,GRM8,GSDMD,HAPLN3,HAVCR1,HBEGF,HCAR2,HELLS,HESX1,HGF,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSD11B1,ICAM1,IDO1,IFI35,IFIH1,IFITM1,IFT122,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL27,IL31RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRF1,IRF4,IRF7,ITGA7,ITGB5,ITK,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ2,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMB3,LBH,LGI2,LILRA2,LILRB3,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MARCKSL1,MARVELD2,MCOLN2,MDGA1,MEFV,MEIKIN,MERTK,MICAL2,MIR503,MMD,MMP9,MTSS1,MYO7B,MYOF,MYOZ2,NCAPG2,NCAPH,NCF1,NDC80,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRN1,NRP1,NYAP2,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OR2I1P,OSM,OVOL1,P2RX4,P2RX7,PADI2,PAQR5,PAQR8,PARP3,PCDH12,PCDHGC3,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PGA3,PGA4,PGA5,PIM1,PIWIL4,PKD1L3,PLAAT3,PLAAT4,PLCD3,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PRKX,PROK2,PRRT2,PSMB10,PTGER4,PXN,PZP,RAD54B,RAD54L,RAPGEF2,RASGRF1,RELB,RHOBTB3,RIPK2,RNF213,RRM2,RSAD2,RTN4RL1,RTP4,RXFP1,S100A10,S100A13,S1PR1,SAT1,SBNO2,SCARF1,SCIMP,SCIN,SCN4B,SCO2,SDC2,SELENOP,SEMA6B,SEPTIN4,SERINC5,SERPING1,SGPL1,SH3PXD2A,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SLC2A5,SLC45A3,SLC4A7,SNX10,SOAT1,SOBP,SOCS1,SOX17,SPATA9,SPTBN4,SRI,SSBP3,SSPN,SSTR2,STAP1,STAT1,STMN1,STX1A,SUCNR1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TANK,TBATA,TBX21,TDRD9,TESC,TGM2,THBD,THBS2,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TRDN,TSPAN32,TYMP,TYMS,TYRO3,UBD,UNG,USP53,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,WWP1,XAF1,XRCC2,XYLT1,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0002757","Term":"immune response-activating signaling pathway","Annotated":396,"Significant":62,"Expected":23.92,"Rank in p.value_classic":80,"p.value_elim":0.27717,"p.value_classic":3.1e-12,"genes":"ACOD1,AIM2,APPL2,AURKB,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CD274,CD28,CD300LF,CD38,CEACAM1,CLEC6A,COLEC12,CTLA4,CTSS,CYLD,DDX60,FCN1,FYB1,GBP1,GBP2,GBP5,GRAMD4,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,IFI35,IFIH1,IRF1,IRF4,IRF7,ITK,KLRK1,LILRA2,LYN,MEFV,NMI,NOD2,NR4A3,OAS3,PDE4B,PLPP4,PLSCR1,RIPK2,RSAD2,SCIMP,STAP1,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF21,TRIM31,TYRO3,ZC3H12A"} {"GO.ID":"GO:0050793","Term":"regulation of developmental process","Annotated":1994,"Significant":153,"Expected":120.43,"Rank in p.value_classic":475,"p.value_elim":0.27721,"p.value_classic":0.00072,"genes":"ADAM8,AGR2,AGT,AMOT,ANKH,APPL2,ASCL2,B2M,BCL2L11,BCL6,BHLHE41,BRCA1,BTN2A2,C21orf91,C3,CASZ1,CCL13,CCL7,CD101,CD28,CD40,CD74,CD80,CD83,CDH5,CDK1,CDS1,CEACAM1,CENPF,CHRD,COLQ,COMP,CSF1,CTLA4,CX3CR1,CXCL10,CXCL9,CYLD,CYSLTR1,DAB1,DAB2,DLL1,DTNBP1,DYNLT1,E2F1,E2F2,EDN1,EGR2,ENPP2,EPHB3,FAXDC2,FGD5,FGL2,FMNL2,FSTL4,GHRL,GLIPR2,GLUL,GRIN3A,HAPLN3,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IFITM1,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITGA7,JAK2,JAK3,KITLG,KLF4,KREMEN1,LAG3,LBH,LILRB3,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MIR503,MMD,MMP9,NPR1,NRCAM,NRP1,OAS2,OSM,P2RX7,PARP3,PDCD1,PDE3B,PID1,PIM1,PLAAT3,PLAAT4,PLXNA2,PML,PRKX,RAPGEF2,RIPK2,RTN4RL1,S100A10,S1PR1,SCARF1,SCIN,SDC2,SEMA6B,SGPL1,SLAMF8,SLC45A3,SOCS1,SOX17,SPTBN4,SSBP3,STAT1,STAT2,SYNE1,SYT1,TAL1,TBX21,TESC,TGM2,THBS2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF13B,TYMP,VCAN,VEGFC,WARS1,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0030217","Term":"T cell differentiation","Annotated":267,"Significant":37,"Expected":16.13,"Rank in p.value_classic":243,"p.value_elim":0.27757,"p.value_classic":1.8e-06,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CD28,CD74,CD80,CD83,CTLA4,CTSL,CYLD,FGL2,GPR183,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,IRF4,ITK,JAK3,LAG3,PTGER4,RELB,RIPK2,RSAD2,SLAMF6,SOCS1,TBX21,TNFSF8,ZC3H12A"} {"GO.ID":"GO:0002285","Term":"lymphocyte activation involved in immune response","Annotated":176,"Significant":30,"Expected":10.63,"Rank in p.value_classic":198,"p.value_elim":0.27916,"p.value_classic":2.1e-07,"genes":"ASCL2,BCL6,CD1C,CD28,CD74,CD80,CEACAM1,DLL1,EXO1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-F,ICAM1,IL12RB1,IL27,IRF4,JAK3,PARP3,PTGER4,RELB,RIPK2,SLAMF6,SLC11A1,TBX21,TNFSF18,UNG,ZC3H12A"} {"GO.ID":"GO:0006974","Term":"DNA damage response","Annotated":843,"Significant":61,"Expected":50.91,"Rank in p.value_classic":1271,"p.value_elim":0.27947,"p.value_classic":0.07853,"genes":"AIM2,ARMT1,BACH1,BCL2A1,BCL2L11,BCL6,BRCA1,CD74,CDC45,CDCA5,CDK1,CHAF1B,CLSPN,CTLA4,DMC1,DTL,DTX3L,E2F1,EEPD1,EME1,ESCO2,EXO1,FANCE,FBXO6,FEN1,GINS2,GTSE1,IRF7,LYN,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MUC1,NEIL3,PARP10,PARP3,PARP9,PCLAF,PMAIP1,PML,POLB,POLE2,PYHIN1,RAD54B,RAD54L,RECQL4,RMI2,TANK,TICRR,TMEM109,TONSL,TOP2A,UBE2T,UHRF1,UNG,WDR76,XRCC2,ZC3H12A"} {"GO.ID":"GO:0045580","Term":"regulation of T cell differentiation","Annotated":157,"Significant":28,"Expected":9.48,"Rank in p.value_classic":197,"p.value_elim":0.28005,"p.value_classic":2e-07,"genes":"ADAM8,ASCL2,BCL6,BTN2A2,CD28,CD74,CD80,CD83,CTLA4,CYLD,FGL2,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,IRF4,JAK3,LAG3,RIPK2,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:1900180","Term":"regulation of protein localization to nucleus","Annotated":133,"Significant":10,"Expected":8.03,"Rank in p.value_classic":2167,"p.value_elim":0.28031,"p.value_classic":0.2829,"genes":"ATP13A2,CDK1,DTX3L,EDN1,GLUL,JAK2,LIMK2,PARP9,PYHIN1,ZC3H12A"} {"GO.ID":"GO:0030101","Term":"natural killer cell activation","Annotated":68,"Significant":12,"Expected":4.11,"Rank in p.value_classic":472,"p.value_elim":0.28178,"p.value_classic":0.00069,"genes":"HLA-E,HLA-F,IL12A,IL15,IL15RA,JAK2,KLRK1,MERTK,SLAMF1,SLAMF7,TICAM2,TYRO3"} {"GO.ID":"GO:0051050","Term":"positive regulation of transport","Annotated":665,"Significant":62,"Expected":40.16,"Rank in p.value_classic":432,"p.value_elim":0.28221,"p.value_classic":0.0004,"genes":"ABCB1,ACSL1,ADAM8,ANK2,APPL2,ATP13A2,ATP1B2,B2M,C2,C3,C4A,C4B,CADPS2,CCL5,CD300LF,CD38,CDK1,CTSS,CXCL10,CXCL11,CXCL9,DAB2,DLL1,DTNBP1,EDN1,EEPD1,ERC2,F2RL3,FCN1,GHRL,HCAR2,HLA-DRB1,HLA-F,IL15,IL15RA,JAK2,KCNE5,KCNJ2,LILRA2,LRRK2,MERTK,NOD2,NPR1,NR4A3,P2RX4,P2RX7,PRRT2,S100A10,SCIN,SCN4B,SLC11A1,SRI,STAP1,STX1A,SYNE1,SYNGR3,SYT1,TESC,TNFRSF11A,TRDN,VEGFC,ZC3H12A"} {"GO.ID":"GO:0002703","Term":"regulation of leukocyte mediated immunity","Annotated":201,"Significant":38,"Expected":12.14,"Rank in p.value_classic":113,"p.value_elim":0.28273,"p.value_classic":2.4e-10,"genes":"B2M,BCL6,C3,CD1A,CD1C,CD28,CD80,CEACAM1,CR1L,CX3CR1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IL12A,IL12RB1,IL4I1,JAK3,KLRK1,LAG3,LTA,LYN,NOD2,P2RX7,PARP3,RSAD2,SCIMP,SLAMF1,SLAMF6,STAP1,TAP2,TBX21,TICAM2"} {"GO.ID":"GO:0042594","Term":"response to starvation","Annotated":179,"Significant":13,"Expected":10.81,"Rank in p.value_classic":2168,"p.value_elim":0.28275,"p.value_classic":0.28577,"genes":"ATF3,CASTOR1,FAS,GLUL,LRRK2,MAP1LC3C,PDK4,PMAIP1,RALB,SESN3,SSTR2,TNFRSF11A,ZC3H12A"} {"GO.ID":"GO:0002822","Term":"regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains","Annotated":169,"Significant":38,"Expected":10.21,"Rank in p.value_classic":75,"p.value_elim":0.28467,"p.value_classic":9.9e-13,"genes":"ASCL2,B2M,BCL6,C3,CD1A,CD1C,CD274,CD28,CD80,CEACAM1,CLEC6A,CR1L,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,IL27,IL4I1,JAK2,JAK3,LTA,NOD2,P2RX7,PARP3,RIPK2,RSAD2,SLAMF1,SLC11A1,TAP2,TBX21,TNFSF13B,ZC3H12A"} {"GO.ID":"GO:0140467","Term":"integrated stress response signaling","Annotated":45,"Significant":4,"Expected":2.72,"Rank in p.value_classic":2182,"p.value_elim":0.28609,"p.value_classic":0.28765,"genes":"AGR2,BATF2,BATF3,MAF"} {"GO.ID":"GO:0001755","Term":"neural crest cell migration","Annotated":45,"Significant":4,"Expected":2.72,"Rank in p.value_classic":2183,"p.value_elim":0.28609,"p.value_classic":0.28765,"genes":"EDN1,KITLG,NRP1,SEMA6B"} {"GO.ID":"GO:0021545","Term":"cranial nerve development","Annotated":45,"Significant":4,"Expected":2.72,"Rank in p.value_classic":2184,"p.value_elim":0.28609,"p.value_classic":0.28765,"genes":"ATP8B1,EGR2,NRP1,TIFAB"} {"GO.ID":"GO:0051973","Term":"positive regulation of telomerase activity","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2169,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"AURKB,KLF4,PKIB"} {"GO.ID":"GO:0000132","Term":"establishment of mitotic spindle orientation","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2170,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"DYNLT1,MAD2L1,NDC80"} {"GO.ID":"GO:0031018","Term":"endocrine pancreas development","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2171,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"DLL1,ONECUT2,SIDT2"} {"GO.ID":"GO:0010665","Term":"regulation of cardiac muscle cell apoptotic process","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2172,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"CAMK2D,GCH1,JAK2"} {"GO.ID":"GO:0007064","Term":"mitotic sister chromatid cohesion","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2173,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"CDCA5,DSCC1,ESCO2"} {"GO.ID":"GO:0033144","Term":"negative regulation of intracellular steroid hormone receptor signaling pathway","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2174,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"BRCA1,DAB2,LBH"} {"GO.ID":"GO:0035094","Term":"response to nicotine","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2175,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"B2M,EDN1,VCAM1"} {"GO.ID":"GO:0071392","Term":"cellular response to estradiol stimulus","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2176,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"CCNA2,CRHBP,SSTR2"} {"GO.ID":"GO:0021879","Term":"forebrain neuron differentiation","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2177,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"B2M,NRP1,RAPGEF2"} {"GO.ID":"GO:0021591","Term":"ventricular system development","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2178,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"ATP1B2,CENPF,RAPGEF2"} {"GO.ID":"GO:1902742","Term":"apoptotic process involved in development","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2179,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"BCL2L11,LRP5,XKR6"} {"GO.ID":"GO:0007622","Term":"rhythmic behavior","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2180,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"C3orf70,EGR2,GHRL"} {"GO.ID":"GO:0010458","Term":"exit from mitosis","Annotated":31,"Significant":3,"Expected":1.87,"Rank in p.value_classic":2181,"p.value_elim":0.28624,"p.value_classic":0.28755,"genes":"ANLN,CDCA5,NPM2"} {"GO.ID":"GO:0014013","Term":"regulation of gliogenesis","Annotated":89,"Significant":7,"Expected":5.38,"Rank in p.value_classic":2186,"p.value_elim":0.28882,"p.value_classic":0.29098,"genes":"ASCL2,CYSLTR1,DAB1,EGR2,LTA,LYN,VEGFC"} {"GO.ID":"GO:0050796","Term":"regulation of insulin secretion","Annotated":119,"Significant":9,"Expected":7.19,"Rank in p.value_classic":2187,"p.value_elim":0.28908,"p.value_classic":0.29158,"genes":"CCL5,CD38,GHRL,HLA-DRB1,JAK2,LRP5,SIDT2,SRI,STX1A"} {"GO.ID":"GO:2000377","Term":"regulation of reactive oxygen species metabolic process","Annotated":119,"Significant":9,"Expected":7.19,"Rank in p.value_classic":2188,"p.value_elim":0.28908,"p.value_classic":0.29158,"genes":"ACOD1,AGT,BRCA1,CTNS,DHFR,GCH1,LRRK2,PID1,ZC3H12A"} {"GO.ID":"GO:0071322","Term":"cellular response to carbohydrate stimulus","Annotated":119,"Significant":9,"Expected":7.19,"Rank in p.value_classic":2189,"p.value_elim":0.28908,"p.value_classic":0.29158,"genes":"COLEC12,GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0023056","Term":"positive regulation of signaling","Annotated":1469,"Significant":118,"Expected":88.72,"Rank in p.value_classic":461,"p.value_elim":0.29007,"p.value_classic":0.00062,"genes":"ADAM8,AGR2,AGT,AMER1,APOL3,APPL2,ATF3,AURKB,BANK1,BCL2L11,BIRC5,C3,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CIBAR1,CLEC6A,CSF1,CTNS,CTSL,CTSS,CX3CR1,CYLD,DAB2,DDX60,DKK2,DLL1,DTNBP1,EDA,EDN1,F2RL3,FAM107A,FAS,G0S2,GADD45B,GAREM1,GBP2,GBP5,GHRL,GLIPR2,GPR183,HBEGF,HCAR2,HGF,HLA-DRB1,ICAM1,IFI35,IFIT5,IL7,IQGAP3,IRF7,JAK2,KITLG,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MMP9,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OSM,P2RX4,P2RX7,PARP14,PARP9,PIM1,PMAIP1,PML,PYHIN1,RALB,RAPGEF2,RASGRF1,RIPK2,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SLAMF1,SLC20A1,SRI,STAMBPL1,STAP1,STX1A,SYT1,TGM2,TICAM2,TIFA,TLR7,TNFAIP8L3,TNFRSF11A,TNFSF10,TRIM22,UBD,ZBP1,ZC3H12A"} {"GO.ID":"GO:0043547","Term":"positive regulation of GTPase activity","Annotated":196,"Significant":14,"Expected":11.84,"Rank in p.value_classic":2194,"p.value_elim":0.29338,"p.value_classic":0.29659,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,RAPGEF2,RASGEF1C,RASGRF1,RSU1,S100A10,TGM2,USP6NL"} {"GO.ID":"GO:0007009","Term":"plasma membrane organization","Annotated":123,"Significant":13,"Expected":7.43,"Rank in p.value_classic":1014,"p.value_elim":0.29372,"p.value_classic":0.03453,"genes":"ANK2,ANO4,ATP8B1,CASP7,CHMP4C,COLEC12,MTSS1,MYOF,P2RX7,PLSCR1,PLSCR4,S100A10,XKR6"} {"GO.ID":"GO:0032024","Term":"positive regulation of insulin secretion","Annotated":60,"Significant":5,"Expected":3.62,"Rank in p.value_classic":2190,"p.value_elim":0.29375,"p.value_classic":0.29556,"genes":"CD38,GHRL,HLA-DRB1,JAK2,SRI"} {"GO.ID":"GO:1904063","Term":"negative regulation of cation transmembrane transport","Annotated":60,"Significant":5,"Expected":3.62,"Rank in p.value_classic":2191,"p.value_elim":0.29375,"p.value_classic":0.29556,"genes":"CAMK2D,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0048278","Term":"vesicle docking","Annotated":60,"Significant":5,"Expected":3.62,"Rank in p.value_classic":2192,"p.value_elim":0.29375,"p.value_classic":0.29556,"genes":"PLEK,RALB,STX11,STX1A,SYT1"} {"GO.ID":"GO:0006721","Term":"terpenoid metabolic process","Annotated":60,"Significant":5,"Expected":3.62,"Rank in p.value_classic":2193,"p.value_elim":0.29375,"p.value_classic":0.29556,"genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"GO.ID":"GO:0098662","Term":"inorganic cation transmembrane transport","Annotated":558,"Significant":37,"Expected":33.7,"Rank in p.value_classic":2213,"p.value_elim":0.29388,"p.value_classic":0.29932,"genes":"ANK2,ASIC1,ATP1B2,ATP6V0D2,CACNA2D3,CAMK2D,CTNS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MCOLN2,P2RX4,P2RX7,PDE4B,PKD1L3,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SRI,TESC,TPCN1,TRDN"} {"GO.ID":"GO:0009746","Term":"response to hexose","Annotated":150,"Significant":11,"Expected":9.06,"Rank in p.value_classic":2195,"p.value_elim":0.29396,"p.value_classic":0.29677,"genes":"GHRL,GJD3,GLUL,HLA-DRB1,ICAM1,LPL,LRP5,NCF1,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0002292","Term":"T cell differentiation involved in immune response","Annotated":76,"Significant":17,"Expected":4.59,"Rank in p.value_classic":250,"p.value_elim":0.29528,"p.value_classic":2.1e-06,"genes":"ASCL2,BCL6,CD80,FGL2,GPR183,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,PTGER4,RELB,RIPK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0030206","Term":"chondroitin sulfate biosynthetic process","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2196,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"DSE,XYLT1"} {"GO.ID":"GO:0034368","Term":"protein-lipid complex remodeling","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2197,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"AGT,LPL"} {"GO.ID":"GO:0034369","Term":"plasma lipoprotein particle remodeling","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2198,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"AGT,LPL"} {"GO.ID":"GO:0034383","Term":"low-density lipoprotein particle clearance","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2199,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"DGAT2,SOAT1"} {"GO.ID":"GO:0045932","Term":"negative regulation of muscle contraction","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2200,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"SRI,ZC3H12A"} {"GO.ID":"GO:0050855","Term":"regulation of B cell receptor signaling pathway","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2201,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"LYN,STAP1"} {"GO.ID":"GO:0050849","Term":"negative regulation of calcium-mediated signaling","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2202,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"MYOZ2,PLEK"} {"GO.ID":"GO:0045061","Term":"thymic T cell selection","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2203,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"CD28,CD74"} {"GO.ID":"GO:0045064","Term":"T-helper 2 cell differentiation","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2204,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"ASCL2,BCL6"} {"GO.ID":"GO:0010954","Term":"positive regulation of protein processing","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2205,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"ADAM8,S100A10"} {"GO.ID":"GO:0007350","Term":"blastoderm segmentation","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2206,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"NRP1,TIFAB"} {"GO.ID":"GO:0061298","Term":"retina vasculature development in camera-type eye","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2207,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"LRP5,NRP1"} {"GO.ID":"GO:0021884","Term":"forebrain neuron development","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2208,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"NRP1,RAPGEF2"} {"GO.ID":"GO:0007141","Term":"male meiosis I","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2209,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"DMC1,TDRD9"} {"GO.ID":"GO:0001845","Term":"phagolysosome assembly","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2210,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"P2RX7,RAB20"} {"GO.ID":"GO:0045762","Term":"positive regulation of adenylate cyclase activity","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2211,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0048634","Term":"regulation of muscle organ development","Annotated":18,"Significant":2,"Expected":1.09,"Rank in p.value_classic":2212,"p.value_elim":0.29612,"p.value_classic":0.29716,"genes":"CENPF,TIFAB"} {"GO.ID":"GO:1903046","Term":"meiotic cell cycle process","Annotated":155,"Significant":20,"Expected":9.36,"Rank in p.value_classic":494,"p.value_elim":0.29703,"p.value_classic":0.00105,"genes":"BCL2L11,CCNE2,CDC25A,DAZL,DMC1,EDN1,EME1,HORMAD1,MEIKIN,NCAPH,NDC80,NPM2,NUF2,OVOL1,PKMYT1,RAD54B,RAD54L,TDRD9,TOP2A,ZWINT"} {"GO.ID":"GO:0035150","Term":"regulation of tube size","Annotated":105,"Significant":8,"Expected":6.34,"Rank in p.value_classic":2215,"p.value_elim":0.29836,"p.value_classic":0.30074,"genes":"AGT,CD38,COMP,CYSLTR1,EDN1,GCH1,HRH2,NPR1"} {"GO.ID":"GO:0035296","Term":"regulation of tube diameter","Annotated":105,"Significant":8,"Expected":6.34,"Rank in p.value_classic":2216,"p.value_elim":0.29836,"p.value_classic":0.30074,"genes":"AGT,CD38,COMP,CYSLTR1,EDN1,GCH1,HRH2,NPR1"} {"GO.ID":"GO:0097746","Term":"blood vessel diameter maintenance","Annotated":105,"Significant":8,"Expected":6.34,"Rank in p.value_classic":2217,"p.value_elim":0.29836,"p.value_classic":0.30074,"genes":"AGT,CD38,COMP,CYSLTR1,EDN1,GCH1,HRH2,NPR1"} {"GO.ID":"GO:0007605","Term":"sensory perception of sound","Annotated":105,"Significant":8,"Expected":6.34,"Rank in p.value_classic":2218,"p.value_elim":0.29836,"p.value_classic":0.30074,"genes":"ATP8B1,BIRC5,CLIC5,MARVELD2,MYO7B,SOBP,SPTBN4,USP53"} {"GO.ID":"GO:0031507","Term":"heterochromatin formation","Annotated":90,"Significant":7,"Expected":5.44,"Rank in p.value_classic":2214,"p.value_elim":0.29848,"p.value_classic":0.30069,"genes":"BAZ1A,BCL6,BRCA1,HELLS,TDRD9,UHRF1,ZNFX1"} {"GO.ID":"GO:0044706","Term":"multi-multicellular organism process","Annotated":148,"Significant":14,"Expected":8.94,"Rank in p.value_classic":1202,"p.value_elim":0.29929,"p.value_classic":0.06355,"genes":"ACOD1,APOL2,CD38,CLIC5,CRHBP,CYP1A1,EDN1,GHRL,IDO1,MAFF,MMP9,PZP,RXFP1,THBD"} {"GO.ID":"GO:0042110","Term":"T cell activation","Annotated":471,"Significant":77,"Expected":28.45,"Rank in p.value_classic":43,"p.value_elim":0.2993,"p.value_classic":5.4e-16,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,BTN3A1,CCL5,CD1C,CD274,CD28,CD7,CD74,CD80,CD83,CEACAM1,CTLA4,CTSL,CXADR,CYLD,FGL1,FGL2,GPR183,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,ICAM1,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,IRF4,ITK,JAK2,JAK3,KITLG,KLRK1,LAG3,LYN,NOD2,P2RX7,PDCD1LG2,PSMB10,PTGER4,RELB,RIPK2,RSAD2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLC11A1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:0039532","Term":"negative regulation of cytoplasmic pattern recognition receptor signaling pathway","Annotated":46,"Significant":4,"Expected":2.78,"Rank in p.value_classic":2219,"p.value_elim":0.29986,"p.value_classic":0.30146,"genes":"AURKB,GRAMD4,MEFV,TRIM31"} {"GO.ID":"GO:0072583","Term":"clathrin-dependent endocytosis","Annotated":46,"Significant":4,"Expected":2.78,"Rank in p.value_classic":2220,"p.value_elim":0.29986,"p.value_classic":0.30146,"genes":"DAB2,DLL1,DNM1,ITSN1"} {"GO.ID":"GO:0072577","Term":"endothelial cell apoptotic process","Annotated":46,"Significant":4,"Expected":2.78,"Rank in p.value_classic":2221,"p.value_elim":0.29986,"p.value_classic":0.30146,"genes":"CD40,CDH5,HLA-G,ICAM1"} {"GO.ID":"GO:0007417","Term":"central nervous system development","Annotated":800,"Significant":52,"Expected":48.32,"Rank in p.value_classic":2235,"p.value_elim":0.30101,"p.value_classic":0.30764,"genes":"AATK,AIM2,ATF5,ATP1B2,B2M,C21orf91,C3,CDKN2C,CELSR1,CENPF,CHRD,CTNS,CX3CR1,DAB1,DLL1,E2F1,EGR2,EPHB3,HAPLN3,HESX1,IFT122,INA,KCNJ10,KIF26A,LRP5,LRRK2,LYN,MARCKSL1,MDGA1,NRCAM,NRP1,OLIG1,PADI2,PLXNA2,RAPGEF2,RTN4RL1,S1PR1,SCIN,SELENOP,SEMA6B,SLC45A3,SPTBN4,SSBP3,SSTR2,SYNGR3,TACC2,TAL1,TNFRSF21,TYRO3,VCAN,WDR62,WWP1"} {"GO.ID":"GO:0042445","Term":"hormone metabolic process","Annotated":151,"Significant":11,"Expected":9.12,"Rank in p.value_classic":2222,"p.value_elim":0.30139,"p.value_classic":0.30424,"genes":"CTNS,CTSL,CYP1A1,DAB2,DGAT2,DHRS3,DHRS9,IL4I1,PLB1,SGPL1,SLC16A10"} {"GO.ID":"GO:0051276","Term":"chromosome organization","Annotated":554,"Significant":57,"Expected":33.46,"Rank in p.value_classic":338,"p.value_elim":0.30175,"p.value_classic":0.00005,"genes":"AURKB,BIRC5,BUB1B,CCNE2,CDC45,CDC6,CDCA5,CDK1,CDT1,CENPF,CENPK,CHMP4C,CHTF18,DMC1,DSCC1,EML4,ESCO2,EXO1,FEN1,GCH1,GINS1,GINS2,HJURP,HORMAD1,KIF11,KIF18B,KIF23,MAD2L1,MCM2,MCM4,MCM5,MCM6,MCM7,MEIKIN,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,NUSAP1,OIP5,PARP3,PKIB,PML,PRC1,RAD54B,RAD54L,RECQL4,RMI2,SPC24,SPC25,TAL1,TOP2A,UHRF1,XRN1,ZWINT"} {"GO.ID":"GO:0051130","Term":"positive regulation of cellular component organization","Annotated":963,"Significant":71,"Expected":58.16,"Rank in p.value_classic":1078,"p.value_elim":0.30193,"p.value_classic":0.04433,"genes":"AGT,ANLN,APPL2,ATP1B2,AURKB,B2M,BCL2L11,C2,C3,C4A,C4B,CALCOCO2,CASP7,CD28,CD300LF,CDH5,CDK1,CXCL9,DAB2,DAZL,DLL1,DTNBP1,EDN1,ENPP2,EPHB3,ERC2,FCN1,FEN1,FSCN1,GBP2,GBP5,GCH1,GHRL,IL15,IL15RA,LRP5,LRRK2,LYN,MERTK,MMP9,MTSS1,NCAPG,NCAPG2,NCAPH,NOD2,NPM2,NRP1,NUSAP1,P2RX7,PKIB,PLEK,PLXNA2,PMAIP1,PML,PPM1E,PRRT2,PXN,RALB,RAPGEF2,S100A10,SCARF1,SCIN,SLC11A1,STAP1,SYNE1,SYT1,TAL1,THBS2,TNFSF10,TRABD2A,WARS1"} {"GO.ID":"GO:0043069","Term":"negative regulation of programmed cell death","Annotated":746,"Significant":56,"Expected":45.06,"Rank in p.value_classic":1134,"p.value_elim":0.30197,"p.value_classic":0.05245,"genes":"ADAM8,AIFM2,ATF5,AURKB,BCL2A1,BCL6,BIRC5,BRCA1,CARD16,CCL5,CD28,CD38,CD74,CDH5,CDK1,COMP,CTNS,CX3CR1,DAB2,DLL1,EDN1,FAS,GCH1,GHRL,HELLS,HGF,ICAM1,IDO1,IFIT3,IL31RA,IL7,IRF7,JAK2,JAK3,KITLG,KLF4,LAMP3,LRRK2,MAD2L1,MERTK,MMP9,MUC1,NOD2,NRP1,PCDHGC3,PDCD1,PDK4,PIM1,PROK2,SYNE1,TMEM109,TNFSF18,TYRO3,UNG,XRCC2,ZC3H12A"} {"GO.ID":"GO:0032870","Term":"cellular response to hormone stimulus","Annotated":471,"Significant":35,"Expected":28.45,"Rank in p.value_classic":1475,"p.value_elim":0.3024,"p.value_classic":0.11832,"genes":"ACOD1,ACSL1,AGT,APPL2,BCL2L11,BRCA1,CCNA2,CDC6,CEACAM1,CRHBP,CTSL,CTSS,DAB2,EDN1,FAM107A,GHRL,GNG2,JAK2,JAK3,LBH,LYN,NR4A3,PADI2,PAQR8,PDE3B,PDK4,PID1,PNPLA3,PTGER4,PXN,RXFP1,SESN3,SOCS1,SSTR2,STAT1"} {"GO.ID":"GO:0010662","Term":"regulation of striated muscle cell apoptotic process","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2223,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"CAMK2D,GCH1,JAK2"} {"GO.ID":"GO:0044546","Term":"NLRP3 inflammasome complex assembly","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2224,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"GBP5,MEFV,TRIM31"} {"GO.ID":"GO:0007140","Term":"male meiotic nuclear division","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2225,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"DMC1,MEIKIN,TDRD9"} {"GO.ID":"GO:0007215","Term":"glutamate receptor signaling pathway","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2226,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"GRIN3A,GRM8,NECAB2"} {"GO.ID":"GO:0071827","Term":"plasma lipoprotein particle organization","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2227,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"AGT,LPL,SOAT1"} {"GO.ID":"GO:0015865","Term":"purine nucleotide transport","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2228,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"ABCC11,ANKH,P2RX7"} {"GO.ID":"GO:0010453","Term":"regulation of cell fate commitment","Annotated":32,"Significant":3,"Expected":1.93,"Rank in p.value_classic":2229,"p.value_elim":0.30303,"p.value_classic":0.30439,"genes":"IL12RB1,SOX17,TBX21"} {"GO.ID":"GO:0042981","Term":"regulation of apoptotic process","Annotated":1208,"Significant":101,"Expected":72.96,"Rank in p.value_classic":438,"p.value_elim":0.30331,"p.value_classic":0.00041,"genes":"ADAM8,AGT,AIFM2,ATF3,ATF5,ATP13A2,AURKB,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,C3orf38,CAMK2D,CARD16,CASP4,CASP7,CCL5,CD274,CD28,CD38,CD40,CD74,CDH5,CDK1,COMP,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DEPTOR,DLL1,E2F1,EDN1,FAS,G0S2,GADD45B,GCH1,GHRL,GIMAP8,HCAR2,HELLS,HGF,HLA-G,HTRA1,ICAM1,IDO1,IFIT2,IFIT3,IGF2R,IL12A,IL31RA,IL7,IRF7,JAK2,JAK3,KITLG,KLF4,LAMP3,LRP5,LRRK2,LTA,LYN,MAD2L1,MERTK,MMP9,MUC1,MYBL2,NOD2,NRP1,P2RX7,PCDHGC3,PDCD1,PDK4,PIM1,PMAIP1,PML,PROK2,RAPGEF2,RIPK2,SCIN,SEPTIN4,STAT1,SYNE1,TGM2,TIFAB,TNFAIP8L3,TNFSF10,TNFSF18,TOP2A,TYRO3,UBD,UNG,XRCC2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0001934","Term":"positive regulation of protein phosphorylation","Annotated":473,"Significant":48,"Expected":28.57,"Rank in p.value_classic":408,"p.value_elim":0.30338,"p.value_classic":0.00028,"genes":"AGT,BANK1,C3,CCL5,CD40,CD74,CD80,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRRK2,LYN,MMD,MMP9,NCF1,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,RALB,RAPGEF2,RIPK2,SLC11A1,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,VEGFC"} {"GO.ID":"GO:1903034","Term":"regulation of response to wounding","Annotated":136,"Significant":10,"Expected":8.21,"Rank in p.value_classic":2230,"p.value_elim":0.30373,"p.value_classic":0.30645,"genes":"CEACAM1,EDN1,ENPP4,HBEGF,KLF4,KREMEN1,RTN4RL1,SCARF1,SERPING1,THBD"} {"GO.ID":"GO:1901615","Term":"organic hydroxy compound metabolic process","Annotated":402,"Significant":27,"Expected":24.28,"Rank in p.value_classic":2242,"p.value_elim":0.30566,"p.value_classic":0.31034,"genes":"APOL1,APOL2,ATP8B1,CTNS,CYP1A1,DAB2,DGAT2,DHFR,DHRS3,DHRS9,EPAS1,FAXDC2,GCH1,GK,HSD3B7,LRP5,NAAA,NPR1,OCA2,OSBPL6,PLB1,PLEK,RAPGEF2,SCARF1,SLC16A10,SOAT1,TTC39B"} {"GO.ID":"GO:0014015","Term":"positive regulation of gliogenesis","Annotated":61,"Significant":5,"Expected":3.68,"Rank in p.value_classic":2231,"p.value_elim":0.3057,"p.value_classic":0.30755,"genes":"CYSLTR1,EGR2,LTA,LYN,VEGFC"} {"GO.ID":"GO:0035924","Term":"cellular response to vascular endothelial growth factor stimulus","Annotated":61,"Significant":5,"Expected":3.68,"Rank in p.value_classic":2232,"p.value_elim":0.3057,"p.value_classic":0.30755,"genes":"DLL1,IL12A,NRP1,VCAM1,VEGFC"} {"GO.ID":"GO:0010827","Term":"regulation of glucose transmembrane transport","Annotated":61,"Significant":5,"Expected":3.68,"Rank in p.value_classic":2233,"p.value_elim":0.3057,"p.value_classic":0.30755,"genes":"APPL2,C3,EDN1,NR4A3,PID1"} {"GO.ID":"GO:0002637","Term":"regulation of immunoglobulin production","Annotated":61,"Significant":5,"Expected":3.68,"Rank in p.value_classic":2234,"p.value_elim":0.3057,"p.value_classic":0.30755,"genes":"BCL6,CD28,HLA-E,PARP3,TBX21"} {"GO.ID":"GO:0001889","Term":"liver development","Annotated":121,"Significant":9,"Expected":7.31,"Rank in p.value_classic":2236,"p.value_elim":0.30577,"p.value_classic":0.30834,"genes":"CEACAM1,CYP1A1,DNAAF1,E2F8,FGL1,HGF,IGF2R,ONECUT2,TYMS"} {"GO.ID":"GO:0035264","Term":"multicellular organism growth","Annotated":121,"Significant":9,"Expected":7.31,"Rank in p.value_classic":2237,"p.value_elim":0.30577,"p.value_classic":0.30834,"genes":"ATF5,COMP,CSF1,G6PC1,GHRL,HESX1,SGPL1,SPTBN4,XRCC2"} {"GO.ID":"GO:0000910","Term":"cytokinesis","Annotated":167,"Significant":12,"Expected":10.09,"Rank in p.value_classic":2238,"p.value_elim":0.30595,"p.value_classic":0.30896,"genes":"ANLN,AURKB,BIRC5,CDC6,CHMP4C,E2F8,IQGAP3,KIF23,NUSAP1,PRC1,SEPTIN4,STMN1"} {"GO.ID":"GO:0001912","Term":"positive regulation of leukocyte mediated cytotoxicity","Annotated":52,"Significant":19,"Expected":3.14,"Rank in p.value_classic":102,"p.value_elim":0.3061,"p.value_classic":6.4e-11,"genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,SLAMF6,STAP1,TAP2"} {"GO.ID":"GO:0051091","Term":"positive regulation of DNA-binding transcription factor activity","Annotated":198,"Significant":14,"Expected":11.96,"Rank in p.value_classic":2239,"p.value_elim":0.30638,"p.value_classic":0.30966,"genes":"AGT,AIM2,CARD16,CD40,EDA,EDN1,NOD2,RHEBL1,RIPK2,TICAM2,TNFRSF11A,TNFSF18,TRIM22,TRIM31"} {"GO.ID":"GO:0048871","Term":"multicellular organismal-level homeostasis","Annotated":634,"Significant":55,"Expected":38.29,"Rank in p.value_classic":633,"p.value_elim":0.30734,"p.value_classic":0.0041,"genes":"ACSL1,ADAM8,AIM2,ALAS1,ANKH,APPL2,ATP1B2,B2M,BCL2L11,BCL6,CD38,CD74,CDH5,COMP,CSF1,CTNS,CX3CR1,CXADR,CYLD,DLL1,EPAS1,FAS,G0S2,GHRL,GPR183,HCAR2,IL15,IL7,IRF4,JAK2,JAK3,KITLG,LYN,MERTK,NCAPG2,NOD2,NR4A3,P2RX4,P2RX7,PDE4B,PDK4,PIWIL4,PMAIP1,POLB,S1PR1,SEPTIN4,SIT1,SLC11A1,SLC12A3,SNX10,STAT1,TAL1,TMEM119,TNFRSF11A,TNFSF13B"} {"GO.ID":"GO:0035023","Term":"regulation of Rho protein signal transduction","Annotated":76,"Significant":6,"Expected":4.59,"Rank in p.value_classic":2240,"p.value_elim":0.30793,"p.value_classic":0.30999,"genes":"BCL6,F2RL3,MCF2L,NRP1,STMN1,TAGAP"} {"GO.ID":"GO:0010469","Term":"regulation of signaling receptor activity","Annotated":76,"Significant":6,"Expected":4.59,"Rank in p.value_classic":2241,"p.value_elim":0.30793,"p.value_classic":0.30999,"genes":"CRHBP,DLGAP3,EDN1,JAK2,NCF1,NRP1"} {"GO.ID":"GO:0060760","Term":"positive regulation of response to cytokine stimulus","Annotated":60,"Significant":14,"Expected":3.62,"Rank in p.value_classic":286,"p.value_elim":0.30796,"p.value_classic":9.8e-06,"genes":"CASP4,CD300LF,CD74,CSF1,EDN1,IFIH1,IL7,IRF7,NLRC5,PARP14,PARP9,RIPK2,TICAM2,ZBP1"} {"GO.ID":"GO:0048878","Term":"chemical homeostasis","Annotated":764,"Significant":63,"Expected":46.14,"Rank in p.value_classic":702,"p.value_elim":0.30817,"p.value_classic":0.00688,"genes":"AGT,ANK2,ANKH,APPL2,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CTNS,CXCL10,CXCL11,CXCL9,DGAT2,EDN1,EPAS1,ERC2,F2RL3,FAM20A,G6PC1,GHRL,GRAMD1B,HLA-DRB1,ICAM1,KCNJ10,KCNJ2,LPL,LRP5,LRRK2,LYN,MT2A,NCF1,NPR1,OCA2,P2RX7,PDK4,PML,PNPLA3,RAB20,SCO2,SESN3,SIDT2,SLAMF8,SLC11A1,SLC12A3,SLC31A2,SLC4A7,SNX10,SOAT1,SRI,STEAP4,SUCNR1,SV2B,TGM2,TRDN,TTC39B"} {"GO.ID":"GO:2000516","Term":"positive regulation of CD4-positive, alpha-beta T cell activation","Annotated":38,"Significant":8,"Expected":2.3,"Rank in p.value_classic":535,"p.value_elim":0.30954,"p.value_classic":0.00165,"genes":"CD28,CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,RIPK2,SOCS1"} {"GO.ID":"GO:0001911","Term":"negative regulation of leukocyte mediated cytotoxicity","Annotated":24,"Significant":7,"Expected":1.45,"Rank in p.value_classic":433,"p.value_elim":0.30959,"p.value_classic":0.0004,"genes":"CEACAM1,CX3CR1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G"} {"GO.ID":"GO:0031032","Term":"actomyosin structure organization","Annotated":183,"Significant":13,"Expected":11.05,"Rank in p.value_classic":2243,"p.value_elim":0.30974,"p.value_classic":0.31291,"genes":"ANLN,EDN1,FRMD3,IQGAP3,ITGB5,MYOZ2,NRP1,PPM1E,PTGER4,PXN,S100A10,S1PR1,STMN1"} {"GO.ID":"GO:0042221","Term":"response to chemical","Annotated":2839,"Significant":257,"Expected":171.46,"Rank in p.value_classic":70,"p.value_elim":0.3098,"p.value_classic":2.3e-13,"genes":"ABCB1,ABCG2,ACOD1,ACSL1,ADAM8,AGR2,AGT,AIFM2,AIM2,ALAS1,AMOT,ANK2,ANKH,AOC3,APPL2,ASIC1,ATF3,ATP13A2,B2M,BCL2L11,BRCA1,C2,C4B,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CBR3,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD274,CD300H,CD300LF,CD38,CD40,CD69,CD74,CD80,CD83,CDC6,CDK1,CDT1,CEACAM1,CENPF,CHAC1,CIITA,CMPK2,COLEC12,COMP,CRHBP,CSF1,CSF2RB,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB2,DERL3,DGAT2,DHFR,DTNBP1,E2F1,EDN1,EGR2,ENPP2,EPAS1,EPHX1,FAM107A,FAS,FBXO6,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GHRL,GJD3,GLUL,GNG2,GPR183,GPR31,GRAMD1B,GRIN3A,GSTK1,HBEGF,HELLS,HESX1,HGF,HLA-DPA1,HLA-DRB1,HSD3B7,ICAM1,IDO1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IQGAP3,IRF1,IRF7,JAK2,JAK3,KCNJ10,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MCM2,MCM7,MEFV,MMP9,MRAS,MT2A,MTUS1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,NRP1,NUB1,OAS2,OAS3,OPTN,OR2I1P,OSM,P2RX4,P2RX7,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PKD1L3,PLSCR1,PLSCR4,PMAIP1,PML,PNPLA3,POLB,PPM1E,PROK2,PTGER4,PTPRU,PXN,PYHIN1,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RELB,RIPK2,RTP4,RUFY4,RXFP1,S1PR1,SBNO2,SCIMP,SELL,SEMA6B,SESN3,SIDT2,SLAMF1,SLAMF8,SLC11A1,SLC12A3,SLC2A5,SNX10,SOCS1,SOX17,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,SUCNR1,SYT1,SYT6,TANK,TAP2,TBX21,TESC,TGM2,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR7,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TYMP,TYMS,UBD,VCAM1,VEGFC,VRK2,XAF1,XRN1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0036037","Term":"CD8-positive, alpha-beta T cell activation","Annotated":23,"Significant":6,"Expected":1.39,"Rank in p.value_classic":548,"p.value_elim":0.30991,"p.value_classic":0.00198,"genes":"CD274,HLA-A,HLA-E,IRF1,SOCS1,TNFSF8"} {"GO.ID":"GO:0033674","Term":"positive regulation of kinase activity","Annotated":261,"Significant":18,"Expected":15.76,"Rank in p.value_classic":2244,"p.value_elim":0.31008,"p.value_classic":0.31386,"genes":"AGT,CCL5,CD40,CD74,CLSPN,CSF1,EDN1,HLA-DRB1,JAK2,LRRK2,MERTK,MMD,NCF1,RALB,RAPGEF2,SLC11A1,TNFRSF11A,TYRO3"} {"GO.ID":"GO:2000193","Term":"positive regulation of fatty acid transport","Annotated":17,"Significant":5,"Expected":1.03,"Rank in p.value_classic":583,"p.value_elim":0.31013,"p.value_classic":0.00267,"genes":"ACSL1,EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0090276","Term":"regulation of peptide hormone secretion","Annotated":137,"Significant":10,"Expected":8.27,"Rank in p.value_classic":2245,"p.value_elim":0.31165,"p.value_classic":0.3144,"genes":"CCL5,CD38,CRHBP,GHRL,HLA-DRB1,JAK2,LRP5,SIDT2,SRI,STX1A"} {"GO.ID":"GO:0042326","Term":"negative regulation of phosphorylation","Annotated":277,"Significant":19,"Expected":16.73,"Rank in p.value_classic":2251,"p.value_elim":0.31183,"p.value_classic":0.31573,"genes":"AGT,CDKN2C,CEACAM1,DEPTOR,DTNBP1,HGF,LRP5,LRRK2,LYN,MVP,NLRP12,PARP14,PID1,PKIB,PPM1E,SOCS1,STAP1,WARS1,ZC3H12A"} {"GO.ID":"GO:0090497","Term":"mesenchymal cell migration","Annotated":47,"Significant":4,"Expected":2.84,"Rank in p.value_classic":2246,"p.value_elim":0.3137,"p.value_classic":0.31535,"genes":"EDN1,KITLG,NRP1,SEMA6B"} {"GO.ID":"GO:0051496","Term":"positive regulation of stress fiber assembly","Annotated":47,"Significant":4,"Expected":2.84,"Rank in p.value_classic":2247,"p.value_elim":0.3137,"p.value_classic":0.31535,"genes":"NRP1,PPM1E,PXN,S100A10"} {"GO.ID":"GO:0046148","Term":"pigment biosynthetic process","Annotated":47,"Significant":4,"Expected":2.84,"Rank in p.value_classic":2248,"p.value_elim":0.3137,"p.value_classic":0.31535,"genes":"ALAS1,CTNS,OCA2,RAPGEF2"} {"GO.ID":"GO:0051898","Term":"negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction","Annotated":47,"Significant":4,"Expected":2.84,"Rank in p.value_classic":2249,"p.value_elim":0.3137,"p.value_classic":0.31535,"genes":"AIM2,BANK1,BTN2A2,HLA-G"} {"GO.ID":"GO:0046503","Term":"glycerolipid catabolic process","Annotated":47,"Significant":4,"Expected":2.84,"Rank in p.value_classic":2250,"p.value_elim":0.3137,"p.value_classic":0.31535,"genes":"ENPP2,LPL,PLB1,PNPLA3"} {"GO.ID":"GO:0032642","Term":"regulation of chemokine production","Annotated":80,"Significant":10,"Expected":4.83,"Rank in p.value_classic":892,"p.value_elim":0.31402,"p.value_classic":0.0218,"genes":"CD74,IL7,KLF4,LPL,MCOLN2,MEFV,NOD2,OAS3,RIPK2,TLR7"} {"GO.ID":"GO:0032368","Term":"regulation of lipid transport","Annotated":103,"Significant":11,"Expected":6.22,"Rank in p.value_classic":1085,"p.value_elim":0.31419,"p.value_classic":0.04623,"genes":"ACSL1,AGT,DAB2,EDN1,EEPD1,GHRL,OSBPL6,P2RX4,P2RX7,TNFRSF11A,TTC39B"} {"GO.ID":"GO:0050768","Term":"negative regulation of neurogenesis","Annotated":122,"Significant":9,"Expected":7.37,"Rank in p.value_classic":2252,"p.value_elim":0.3142,"p.value_classic":0.31681,"genes":"APPL2,ASCL2,B2M,DAB1,DYNLT1,FSTL4,NRP1,RAPGEF2,SEMA6B"} {"GO.ID":"GO:0050954","Term":"sensory perception of mechanical stimulus","Annotated":122,"Significant":9,"Expected":7.37,"Rank in p.value_classic":2253,"p.value_elim":0.3142,"p.value_classic":0.31681,"genes":"ATP8B1,BIRC5,CLIC5,MARVELD2,MYO7B,P2RX4,SOBP,SPTBN4,USP53"} {"GO.ID":"GO:0034765","Term":"regulation of monoatomic ion transmembrane transport","Annotated":239,"Significant":25,"Expected":14.43,"Rank in p.value_classic":663,"p.value_elim":0.31491,"p.value_classic":0.0052,"genes":"ABCB1,ANK2,ATP1B2,CAMK2D,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PML,SCN4B,SLC31A2,SRI,TESC,TRDN"} {"GO.ID":"GO:0050877","Term":"nervous system process","Annotated":724,"Significant":47,"Expected":43.73,"Rank in p.value_classic":2295,"p.value_elim":0.31567,"p.value_classic":0.32209,"genes":"ASIC1,ATP8B1,B2M,BIRC5,CBR3,CLIC5,COMP,CRHBP,CTNS,CX3CR1,DHRS3,DLGAP3,EGR2,EPAS1,FAM107A,FEN1,GABRA3,GCH1,GHRL,GRIN3A,GRM8,HLA-DRA,INSYN2A,KCNJ10,KCNJ2,LRRK2,MARVELD2,MYO7B,NRCAM,OR2I1P,P2RX4,P2RX7,PKD1L3,PROK2,PRRT2,RASGRF1,RTP4,S1PR1,SCN4B,SOBP,SPTBN4,STX1A,SYNE1,TIFAB,TNFRSF21,TYMP,USP53"} {"GO.ID":"GO:0006310","Term":"DNA recombination","Annotated":291,"Significant":26,"Expected":17.58,"Rank in p.value_classic":965,"p.value_elim":0.31602,"p.value_classic":0.02938,"genes":"BCL6,BRCA1,CD28,CDC45,DMC1,EME1,EXO1,FEN1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,PARP3,POLB,RAD54B,RAD54L,RECQL4,RMI2,TBX21,TONSL,TOP2A,UHRF1,UNG,XRCC2"} {"GO.ID":"GO:0045453","Term":"bone resorption","Annotated":54,"Significant":9,"Expected":3.26,"Rank in p.value_classic":651,"p.value_elim":0.31617,"p.value_classic":0.00468,"genes":"ADAM8,CD38,IL7,P2RX7,PDK4,S1PR1,SNX10,TMEM119,TNFRSF11A"} {"GO.ID":"GO:1904019","Term":"epithelial cell apoptotic process","Annotated":107,"Significant":8,"Expected":6.46,"Rank in p.value_classic":2255,"p.value_elim":0.31639,"p.value_classic":0.31884,"genes":"CD40,CDH5,E2F1,E2F2,HLA-G,ICAM1,JAK2,USP53"} {"GO.ID":"GO:0071331","Term":"cellular response to hexose stimulus","Annotated":107,"Significant":8,"Expected":6.46,"Rank in p.value_classic":2256,"p.value_elim":0.31639,"p.value_classic":0.31884,"genes":"GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0002347","Term":"response to tumor cell","Annotated":36,"Significant":7,"Expected":2.17,"Rank in p.value_classic":658,"p.value_elim":0.31667,"p.value_classic":0.00511,"genes":"CD274,CEACAM1,HLA-A,HLA-DRB1,IL12A,IL4I1,KLF4"} {"GO.ID":"GO:0050776","Term":"regulation of immune response","Annotated":726,"Significant":131,"Expected":43.85,"Rank in p.value_classic":10,"p.value_elim":0.31698,"genes":"ACOD1,ADAM8,AIM2,APPL2,ASCL2,AURKB,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CTLA4,CTSS,CYLD,DDX60,FCN1,FGL1,FGL2,FYB1,GBP1,GBP2,GBP5,GPR31,GRAMD4,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL27,IL4I1,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KARS1,KLRK1,LAG3,LILRA2,LTA,LYN,MEFV,NCF1,NLRC5,NMI,NOD2,NR4A3,OAS3,P2RX7,PARP14,PARP3,PARP9,PDCD1,PDE4B,PLPP4,PLSCR1,PYHIN1,RIPK2,RSAD2,SCIMP,SERPING1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,STAP1,STAT2,TAP2,TBX21,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF14,TNFRSF21,TNFSF13B,TRAFD1,TRIM31,TYRO3,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0072001","Term":"renal system development","Annotated":278,"Significant":19,"Expected":16.79,"Rank in p.value_classic":2294,"p.value_elim":0.3174,"p.value_classic":0.32134,"genes":"AGT,AMER1,BCL2L11,CENPF,CTNS,DLL1,EDN1,GCNT3,HELLS,LRRK2,MMP9,MTSS1,NRP1,OVOL1,PKD1L3,PRKX,SGPL1,SOX17,STAT1"} {"GO.ID":"GO:0045685","Term":"regulation of glial cell differentiation","Annotated":62,"Significant":5,"Expected":3.74,"Rank in p.value_classic":2257,"p.value_elim":0.31772,"p.value_classic":0.31961,"genes":"CDK1,DAB1,EGR2,SLC45A3,TNFRSF21"} {"GO.ID":"GO:0043299","Term":"leukocyte degranulation","Annotated":62,"Significant":5,"Expected":3.74,"Rank in p.value_classic":2258,"p.value_elim":0.31772,"p.value_classic":0.31961,"genes":"CEACAM1,HLA-F,LYN,NR4A3,S100A13"} {"GO.ID":"GO:0043502","Term":"regulation of muscle adaptation","Annotated":62,"Significant":5,"Expected":3.74,"Rank in p.value_classic":2259,"p.value_elim":0.31772,"p.value_classic":0.31961,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0031399","Term":"regulation of protein modification process","Annotated":1066,"Significant":84,"Expected":64.38,"Rank in p.value_classic":697,"p.value_elim":0.31811,"p.value_classic":0.0065,"genes":"AGT,AMER1,BANK1,C3,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DEPTOR,DTNBP1,DTX3L,EDN1,ENPP2,EPAS1,FAM107A,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,KITLG,LIMK2,LRP5,LRRK2,LYN,MAD2L1,MMD,MMP9,MVP,NCF1,NLRP12,NMI,NOD2,NRP1,OSM,P2RX7,PARP10,PARP14,PARP9,PID1,PKIB,PKMYT1,PML,PPM1E,RALB,RAPGEF2,RIPK2,SEPTIN4,SLC11A1,SOCS1,SPTBN4,STAT2,TANK,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TRABD2A,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0035282","Term":"segmentation","Annotated":77,"Significant":6,"Expected":4.65,"Rank in p.value_classic":2287,"p.value_elim":0.31867,"p.value_classic":0.32077,"genes":"DLL1,EGR2,NRP1,PLXNA2,TIFAB,XRCC2"} {"GO.ID":"GO:1901890","Term":"positive regulation of cell junction assembly","Annotated":77,"Significant":6,"Expected":4.65,"Rank in p.value_classic":2288,"p.value_elim":0.31867,"p.value_classic":0.32077,"genes":"AGT,EPHB3,GHRL,NRP1,S100A10,THBS2"} {"GO.ID":"GO:0006691","Term":"leukotriene metabolic process","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2260,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"GGT5,LTC4S"} {"GO.ID":"GO:0014047","Term":"glutamate secretion","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2261,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"DTNBP1,P2RX7"} {"GO.ID":"GO:0000303","Term":"response to superoxide","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2262,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0009163","Term":"nucleoside biosynthetic process","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2263,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"PRTFDC1,TK1"} {"GO.ID":"GO:0045662","Term":"negative regulation of myoblast differentiation","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2264,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"CXCL10,DLL1"} {"GO.ID":"GO:0042044","Term":"fluid transport","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2265,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"CTNS,EDN1"} {"GO.ID":"GO:0046931","Term":"pore complex assembly","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2266,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"GSDMD,P2RX7"} {"GO.ID":"GO:0002070","Term":"epithelial cell maturation","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2267,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"EPAS1,TYMS"} {"GO.ID":"GO:0034312","Term":"diol biosynthetic process","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2268,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0010882","Term":"regulation of cardiac muscle contraction by calcium ion signaling","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2269,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"ANK2,CAMK2D"} {"GO.ID":"GO:0070286","Term":"axonemal dynein complex assembly","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2270,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"DNAAF1,LRRC61"} {"GO.ID":"GO:0034404","Term":"nucleobase-containing small molecule biosynthetic process","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2271,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"PRTFDC1,TK1"} {"GO.ID":"GO:0003323","Term":"type B pancreatic cell development","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2272,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"DLL1,SIDT2"} {"GO.ID":"GO:0034260","Term":"negative regulation of GTPase activity","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2273,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"KLRK1,LRRK2"} {"GO.ID":"GO:0002385","Term":"mucosal immune response","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2274,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"H2BC21,NOD2"} {"GO.ID":"GO:1901020","Term":"negative regulation of calcium ion transmembrane transporter activity","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2275,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"SRI,TRDN"} {"GO.ID":"GO:0071498","Term":"cellular response to fluid shear stress","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2276,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"KLF4,MTSS1"} {"GO.ID":"GO:0034505","Term":"tooth mineralization","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2277,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"ANKH,FAM20A"} {"GO.ID":"GO:0034695","Term":"response to prostaglandin E","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2278,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"GNG2,PTGER4"} {"GO.ID":"GO:0036498","Term":"IRE1-mediated unfolded protein response","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2279,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"AGR2,BCL2L11"} {"GO.ID":"GO:0046782","Term":"regulation of viral transcription","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2280,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"IFITM3,TRIM31"} {"GO.ID":"GO:0071800","Term":"podosome assembly","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2281,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"ASB2,FSCN1"} {"GO.ID":"GO:0043931","Term":"ossification involved in bone maturation","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2282,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"SNX10,XYLT1"} {"GO.ID":"GO:0006706","Term":"steroid catabolic process","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2283,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"HSD11B1,SCARF1"} {"GO.ID":"GO:0060037","Term":"pharyngeal system development","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2284,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"EDN1,PLXNA2"} {"GO.ID":"GO:0071636","Term":"positive regulation of transforming growth factor beta production","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2285,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0030318","Term":"melanocyte differentiation","Annotated":19,"Significant":2,"Expected":1.15,"Rank in p.value_classic":2286,"p.value_elim":0.31885,"p.value_classic":0.31995,"genes":"KITLG,OCA2"} {"GO.ID":"GO:0048771","Term":"tissue remodeling","Annotated":143,"Significant":15,"Expected":8.64,"Rank in p.value_classic":949,"p.value_elim":0.31938,"p.value_classic":0.02591,"genes":"ADAM8,AGT,CD38,CEACAM1,CYP1A1,EPAS1,IL15,IL7,LRP5,P2RX7,PDK4,S1PR1,SNX10,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0051241","Term":"negative regulation of multicellular organismal process","Annotated":884,"Significant":94,"Expected":53.39,"Rank in p.value_classic":165,"p.value_elim":0.3195,"p.value_classic":3.5e-08,"genes":"ACOD1,AMOT,APPL2,ASCL2,B2M,BANK1,BCL6,BTN2A2,CARD16,CD274,CD300LF,CD38,CD74,CD80,CD83,CEACAM1,CRHBP,CTLA4,CX3CR1,CXCL10,CYLD,DAB1,DLL1,DYNLT1,E2F2,EDN1,FGL1,FGL2,FSTL4,GBP1,GBP7,GHRL,GJD3,HGF,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IL12A,IL15,IL31RA,IL4I1,IRF1,JAK3,KLF4,KREMEN1,LAG3,LILRB3,LYN,MEFV,MERTK,MIR503,NLRP12,NMI,NOD2,NPR1,NRP1,OAS3,P2RX4,P2RX7,PARP3,PDCD1,PDCD1LG2,PDE3B,PDE4B,PML,PTGER4,RAPGEF2,RELB,SEMA6B,SERPING1,SLAMF1,SLAMF8,SLC11A1,SOCS1,SPTBN4,SRI,STAT1,TBX21,THBD,THBS2,TIFAB,TLR8,TMEM119,TMEM176A,TMEM176B,TNFAIP6,TNFRSF14,TNFRSF21,TSPAN32,TYRO3,XAF1,ZC3H12A"} {"GO.ID":"GO:0043409","Term":"negative regulation of MAPK cascade","Annotated":138,"Significant":10,"Expected":8.33,"Rank in p.value_classic":2296,"p.value_elim":0.31961,"p.value_classic":0.3224,"genes":"AGT,ATF3,BTN2A2,CYLD,DAB2,GBP1,LYN,MIR503,NLRP12,P2RX7"} {"GO.ID":"GO:0140632","Term":"canonical inflammasome complex assembly","Annotated":33,"Significant":3,"Expected":1.99,"Rank in p.value_classic":2289,"p.value_elim":0.31986,"p.value_classic":0.32127,"genes":"GBP5,MEFV,TRIM31"} {"GO.ID":"GO:0032872","Term":"regulation of stress-activated MAPK cascade","Annotated":33,"Significant":3,"Expected":1.99,"Rank in p.value_classic":2290,"p.value_elim":0.31986,"p.value_classic":0.32127,"genes":"FAS,NOD2,SCIMP"} {"GO.ID":"GO:1902253","Term":"regulation of intrinsic apoptotic signaling pathway by p53 class mediator","Annotated":33,"Significant":3,"Expected":1.99,"Rank in p.value_classic":2291,"p.value_elim":0.31986,"p.value_classic":0.32127,"genes":"CD74,MUC1,TIFAB"} {"GO.ID":"GO:2000649","Term":"regulation of sodium ion transmembrane transporter activity","Annotated":33,"Significant":3,"Expected":1.99,"Rank in p.value_classic":2292,"p.value_elim":0.31986,"p.value_classic":0.32127,"genes":"CAMK2D,SCN4B,TESC"} {"GO.ID":"GO:1905476","Term":"negative regulation of protein localization to membrane","Annotated":33,"Significant":3,"Expected":1.99,"Rank in p.value_classic":2293,"p.value_elim":0.31986,"p.value_classic":0.32127,"genes":"DAB2,GBP1,PID1"} {"GO.ID":"GO:0140352","Term":"export from cell","Annotated":686,"Significant":66,"Expected":41.43,"Rank in p.value_classic":363,"p.value_elim":0.32009,"p.value_classic":0.0001,"genes":"ABCB1,ABCG2,ADAM8,ADORA3,AGT,ASIC1,ATP13A2,ATP1B2,C1QTNF5,CADPS2,CCL5,CCL8,CD38,CEACAM1,COMP,CRHBP,DAB2,DTNBP1,DYSF,EDN1,ERC2,EXOC3L1,EXOC3L4,GHRL,GSDMD,HCAR2,HLA-DRB1,HLA-F,IL12A,IL1RN,ITSN1,JAK2,KCNE5,LRP5,LRRK2,LYN,MCTP2,MERTK,MYOF,NR4A3,OSM,P2RX4,P2RX7,PLEK,PRRT2,RALB,RSAD2,S100A10,S100A13,SCIN,SEPTIN4,SIDT2,SLC16A10,SRI,STX11,STX1A,SUCNR1,SV2B,SYNGR3,SYT1,SYT6,TGM2,TNFAIP2,TNFRSF11A,TYRO3,VEGFC"} {"GO.ID":"GO:0009628","Term":"response to abiotic stimulus","Annotated":935,"Significant":60,"Expected":56.47,"Rank in p.value_classic":2301,"p.value_elim":0.32035,"p.value_classic":0.32774,"genes":"ABCB1,ADAM8,APPL2,ASCL2,ASIC1,AURKB,BRCA1,CASP7,CCL7,CCNA2,CD38,CD40,CDC25A,CDS1,CTNS,CTSS,CXCL10,CYP1A1,CYSLTR1,DTL,EDN1,EPAS1,FAS,FEN1,GHRL,GPR31,HSBP1L1,IL12A,IRF1,KARS1,KCNJ2,LTA,LYN,MMP9,P2RX7,PCLAF,PKD1L3,PMAIP1,PML,POLB,PTGER4,RAD54B,RAD54L,RELB,STAT1,SYNE1,TANK,TFEC,THBD,TICRR,TIFAB,TLR5,TLR7,TLR8,TMEM109,TNFRSF11A,USP53,VCAM1,VEGFC,XRCC2"} {"GO.ID":"GO:0034101","Term":"erythrocyte homeostasis","Annotated":123,"Significant":9,"Expected":7.43,"Rank in p.value_classic":2297,"p.value_elim":0.32268,"p.value_classic":0.32532,"genes":"ALAS1,B2M,BCL6,EPAS1,JAK2,LYN,NCAPG2,STAT1,TAL1"} {"GO.ID":"GO:0055088","Term":"lipid homeostasis","Annotated":123,"Significant":9,"Expected":7.43,"Rank in p.value_classic":2298,"p.value_elim":0.32268,"p.value_classic":0.32532,"genes":"ATP13A2,DGAT2,G6PC1,GRAMD1B,LPL,LRP5,PNPLA3,SOAT1,TTC39B"} {"GO.ID":"GO:0048232","Term":"male gamete generation","Annotated":390,"Significant":26,"Expected":23.55,"Rank in p.value_classic":2303,"p.value_elim":0.32373,"p.value_classic":0.32843,"genes":"ADGB,BCL2L11,BCL6,DAZL,DMC1,HORMAD1,IGF2R,LIMK2,LRRK2,MEIKIN,MERTK,OCA2,OVOL1,PIWIL4,PROK2,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TMEM119,TYRO3,ZMYND15"} {"GO.ID":"GO:0010594","Term":"regulation of endothelial cell migration","Annotated":154,"Significant":11,"Expected":9.3,"Rank in p.value_classic":2299,"p.value_elim":0.32397,"p.value_classic":0.32693,"genes":"AGT,CD40,CEACAM1,EDN1,GLUL,KLF4,MIR503,NRP1,P2RX4,VEGFC,ZC3H12A"} {"GO.ID":"GO:0034284","Term":"response to monosaccharide","Annotated":154,"Significant":11,"Expected":9.3,"Rank in p.value_classic":2300,"p.value_elim":0.32397,"p.value_classic":0.32693,"genes":"GHRL,GJD3,GLUL,HLA-DRB1,ICAM1,LPL,LRP5,NCF1,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0071326","Term":"cellular response to monosaccharide stimulus","Annotated":108,"Significant":8,"Expected":6.52,"Rank in p.value_classic":2302,"p.value_elim":0.32548,"p.value_classic":0.32797,"genes":"GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,SIDT2,SLC2A5,SRI"} {"GO.ID":"GO:0016079","Term":"synaptic vesicle exocytosis","Annotated":81,"Significant":10,"Expected":4.89,"Rank in p.value_classic":899,"p.value_elim":0.32601,"p.value_classic":0.02358,"genes":"CADPS2,DTNBP1,ERC2,LRRK2,P2RX7,PRRT2,STX11,STX1A,SV2B,SYT1"} {"GO.ID":"GO:0032602","Term":"chemokine production","Annotated":81,"Significant":10,"Expected":4.89,"Rank in p.value_classic":900,"p.value_elim":0.32601,"p.value_classic":0.02358,"genes":"CD74,IL7,KLF4,LPL,MCOLN2,MEFV,NOD2,OAS3,RIPK2,TLR7"} {"GO.ID":"GO:0071383","Term":"cellular response to steroid hormone stimulus","Annotated":170,"Significant":12,"Expected":10.27,"Rank in p.value_classic":2309,"p.value_elim":0.32751,"p.value_classic":0.33063,"genes":"ACOD1,BCL2L11,BRCA1,DAB2,EDN1,FAM107A,JAK2,LBH,NR4A3,PADI2,PAQR8,SSTR2"} {"GO.ID":"GO:0038093","Term":"Fc receptor signaling pathway","Annotated":48,"Significant":4,"Expected":2.9,"Rank in p.value_classic":2304,"p.value_elim":0.3276,"p.value_classic":0.32929,"genes":"APPL2,LYN,NR4A3,PLPP4"} {"GO.ID":"GO:2000117","Term":"negative regulation of cysteine-type endopeptidase activity","Annotated":48,"Significant":4,"Expected":2.9,"Rank in p.value_classic":2305,"p.value_elim":0.3276,"p.value_classic":0.32929,"genes":"CARD16,KLF4,LAMP3,MMP9"} {"GO.ID":"GO:0040014","Term":"regulation of multicellular organism growth","Annotated":48,"Significant":4,"Expected":2.9,"Rank in p.value_classic":2306,"p.value_elim":0.3276,"p.value_classic":0.32929,"genes":"CSF1,GHRL,SGPL1,SPTBN4"} {"GO.ID":"GO:0043281","Term":"regulation of cysteine-type endopeptidase activity involved in apoptotic process","Annotated":139,"Significant":10,"Expected":8.39,"Rank in p.value_classic":2308,"p.value_elim":0.32762,"p.value_classic":0.33045,"genes":"CARD16,FAS,GRAMD4,JAK2,KLF4,LAMP3,MMP9,NLRP12,PMAIP1,TNFSF10"} {"GO.ID":"GO:0042476","Term":"odontogenesis","Annotated":93,"Significant":7,"Expected":5.62,"Rank in p.value_classic":2307,"p.value_elim":0.32784,"p.value_classic":0.33017,"genes":"ANKH,BCL2L11,CSF1,EDA,EDN1,FAM20A,SNX10"} {"GO.ID":"GO:0055085","Term":"transmembrane transport","Annotated":1065,"Significant":76,"Expected":64.32,"Rank in p.value_classic":1245,"p.value_elim":0.32888,"p.value_classic":0.06922,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ANK2,ANKH,ANO4,APOL1,APPL2,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,BCL2A1,C3,CACNA2D3,CALHM6,CAMK2D,CLIC5,CRHBP,CTNS,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,FLVCR2,GABRA3,GJD3,GRIN3A,GSDMA,GSDMD,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MCOLN2,MMP9,NR4A3,OCA2,P2RX4,P2RX7,PDE4B,PID1,PIM1,PKD1L3,PML,SCN4B,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SRI,SV2B,TAP1,TAP2,TESC,TMEM109,TMEM144,TPCN1,TRDN,WWP1"} {"GO.ID":"GO:0002521","Term":"leukocyte differentiation","Annotated":522,"Significant":67,"Expected":31.53,"Rank in p.value_classic":135,"p.value_elim":0.32912,"p.value_classic":3e-09,"genes":"ADAM8,ASCL2,B2M,BATF2,BATF3,BCL6,BTN2A2,CD101,CD28,CD74,CD80,CD83,CEACAM1,CSF1,CTLA4,CTSL,CYLD,DLL1,FGL2,GPR183,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK3,KITLG,LAG3,LILRB3,LYN,MERTK,MMP9,PTGER4,RELB,RIPK2,RSAD2,SBNO2,SH3PXD2A,SLAMF1,SLAMF6,SLAMF8,SNX10,SOCS1,TAL1,TBX21,TESC,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFSF13B,TNFSF8,TYRO3,UBD,VCAM1,ZC3H12A"} {"GO.ID":"GO:0019935","Term":"cyclic-nucleotide-mediated signaling","Annotated":63,"Significant":5,"Expected":3.8,"Rank in p.value_classic":2310,"p.value_elim":0.32979,"p.value_classic":0.33172,"genes":"IRAG1,NPR1,PDE3B,PDE4B,RAPGEF2"} {"GO.ID":"GO:0014855","Term":"striated muscle cell proliferation","Annotated":63,"Significant":5,"Expected":3.8,"Rank in p.value_classic":2311,"p.value_elim":0.32979,"p.value_classic":0.33172,"genes":"CDK1,HGF,JAK2,NDC80,PIM1"} {"GO.ID":"GO:0048488","Term":"synaptic vesicle endocytosis","Annotated":63,"Significant":5,"Expected":3.8,"Rank in p.value_classic":2312,"p.value_elim":0.32979,"p.value_classic":0.33172,"genes":"DNM1,ITSN1,LRRK2,STX1A,SYT1"} {"GO.ID":"GO:0007200","Term":"phospholipase C-activating G protein-coupled receptor signaling pathway","Annotated":63,"Significant":5,"Expected":3.8,"Rank in p.value_classic":2313,"p.value_elim":0.32979,"p.value_classic":0.33172,"genes":"AGT,CX3CR1,EDN1,S1PR1,TGM2"} {"GO.ID":"GO:0141124","Term":"intracellular signaling cassette","Annotated":1577,"Significant":124,"Expected":95.24,"Rank in p.value_classic":492,"p.value_elim":0.33038,"p.value_classic":0.00102,"genes":"ADAM8,AGT,AIM2,AMOT,ANK2,APOL3,ATF3,BANK1,BCL6,BTN2A2,CAMK2D,CARD16,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD28,CD40,CD74,CDK1,CEACAM1,CELSR1,CLEC6A,CSF1,CX3CR1,CXCR3,CYLD,DAB1,DAB2,EDA,EDN1,F2RL3,FAM13A,FAS,FGD5,GADD45B,GAREM1,GBP1,GBP7,GHRL,GLIPR2,GPR183,HBEGF,HESX1,HGF,HLA-DRB1,HLA-G,ICAM1,IFI35,IFIT5,IL31RA,IQGAP3,IRAG1,ITSN1,JAK2,KARS1,KITLG,LBH,LITAF,LRRK2,LYN,MCF2L,MCOLN2,MCTP2,MERTK,MIR503,MRAS,MYOZ2,NCF1,NECAB2,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,NUCB1,NYAP2,OPTN,OSM,P2RX4,P2RX7,PDE3B,PDE4B,PLEK,PML,PTGER4,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,RHEBL1,RIPK2,S100A13,SCIMP,SECTM1,SESN3,SLAMF1,SLC20A1,STAT1,STMN1,TAGAP,TANK,TGM2,TICAM2,TIFA,TIFAB,TLR7,TLR8,TNFAIP8L3,TNFRSF11A,TNFSF10,TPCN1,TRIM22,TYRO3,UBD,VCAM1,VRK2,ZC3H12A"} {"GO.ID":"GO:0051348","Term":"negative regulation of transferase activity","Annotated":186,"Significant":13,"Expected":11.23,"Rank in p.value_classic":2314,"p.value_elim":0.33042,"p.value_classic":0.33369,"genes":"AGT,CEACAM1,DEPTOR,DTNBP1,DTX3L,LRP5,LYN,MAD2L1,MVP,PARP3,PKIB,PPM1E,WARS1"} {"GO.ID":"GO:0022402","Term":"cell cycle process","Annotated":1117,"Significant":104,"Expected":67.46,"Rank in p.value_classic":267,"p.value_elim":0.33117,"p.value_classic":4.2e-06,"genes":"ABCB1,ANLN,APPL2,ATF5,AURKB,BCL2L11,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CENPK,CENPM,CENPU,CHMP4C,CLSPN,CYP1A1,DAZL,DMC1,DSCC1,DTL,DTX3L,DYNLT1,E2F1,E2F8,EDN1,EME1,EML4,ESCO2,FAM107A,FBXO6,FEN1,GINS1,GTSE1,HJURP,HLA-G,HORMAD1,IQGAP3,KIF11,KIF18B,KIF23,KLF4,LIMK2,LRP5,MAD2L1,MCM2,MCM4,MCM6,MEIKIN,MIR503,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,OIP5,ORC1,OVOL1,PARP3,PARP9,PCLAF,PKMYT1,PLSCR1,PML,PRC1,PSME1,PSME2,RAD54B,RAD54L,RMI2,RRM2,SEPTIN4,SPC24,SPC25,STMN1,TACC2,TDRD9,TICRR,TK1,TOP2A,UBD,UHRF1,WDR62,WDR76,WEE1,XRCC2,ZWINT"} {"GO.ID":"GO:0032652","Term":"regulation of interleukin-1 production","Annotated":95,"Significant":19,"Expected":5.74,"Rank in p.value_classic":257,"p.value_elim":0.33422,"p.value_classic":3.2e-06,"genes":"AIM2,CARD16,CEACAM1,CX3CR1,GBP5,GHRL,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,PML,RIPK2,S100A13,TLR8,ZC3H12A"} {"GO.ID":"GO:0032612","Term":"interleukin-1 production","Annotated":95,"Significant":19,"Expected":5.74,"Rank in p.value_classic":258,"p.value_elim":0.33422,"p.value_classic":3.2e-06,"genes":"AIM2,CARD16,CEACAM1,CX3CR1,GBP5,GHRL,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,PML,RIPK2,S100A13,TLR8,ZC3H12A"} {"GO.ID":"GO:0030048","Term":"actin filament-based movement","Annotated":109,"Significant":8,"Expected":6.58,"Rank in p.value_classic":2315,"p.value_elim":0.33461,"p.value_classic":0.33714,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,MYO7B,PDE4B,SCN4B,SRI"} {"GO.ID":"GO:0044770","Term":"cell cycle phase transition","Annotated":495,"Significant":54,"Expected":29.9,"Rank in p.value_classic":307,"p.value_elim":0.33479,"p.value_classic":0.00002,"genes":"ABCB1,ANLN,APPL2,ATF5,AURKB,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKN2C,CDT1,CENPF,CHMP4C,CLSPN,CYP1A1,DTL,DTX3L,E2F1,EME1,FAM107A,FBXO6,GTSE1,HORMAD1,IQGAP3,KLF4,MAD2L1,MIR503,MUC1,NDC80,NPM2,NUF2,ORC1,OVOL1,PARP9,PKMYT1,PML,PSME1,PSME2,RRM2,SPC24,SPC25,TICRR,UBD,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0042327","Term":"positive regulation of phosphorylation","Annotated":512,"Significant":50,"Expected":30.92,"Rank in p.value_classic":452,"p.value_elim":0.33519,"p.value_classic":0.00051,"genes":"AGT,BANK1,C3,CCL5,CD40,CD74,CD80,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRRK2,LYN,MERTK,MMD,MMP9,NCF1,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,RALB,RAPGEF2,RIPK2,SLC11A1,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC"} {"GO.ID":"GO:0010821","Term":"regulation of mitochondrion organization","Annotated":140,"Significant":10,"Expected":8.46,"Rank in p.value_classic":2326,"p.value_elim":0.33567,"p.value_classic":0.33853,"genes":"ATP13A2,BCL2L11,HGF,LRRK2,MMP9,NOD2,PID1,PMAIP1,STAT2,TNFSF10"} {"GO.ID":"GO:0048839","Term":"inner ear development","Annotated":140,"Significant":10,"Expected":8.46,"Rank in p.value_classic":2327,"p.value_elim":0.33567,"p.value_classic":0.33853,"genes":"ATP8B1,C1QTNF5,CCNA2,DLL1,HESX1,MAF,MCM2,SLC4A7,SOBP,TIFAB"} {"GO.ID":"GO:0043066","Term":"negative regulation of apoptotic process","Annotated":723,"Significant":54,"Expected":43.67,"Rank in p.value_classic":1182,"p.value_elim":0.33581,"p.value_classic":0.06035,"genes":"ADAM8,ATF5,AURKB,BCL2A1,BCL6,BIRC5,BRCA1,CARD16,CCL5,CD28,CD38,CD74,CDH5,CDK1,COMP,CTNS,CX3CR1,DAB2,DLL1,EDN1,FAS,GCH1,GHRL,HELLS,HGF,ICAM1,IDO1,IFIT3,IL31RA,IL7,IRF7,JAK2,JAK3,KITLG,KLF4,LAMP3,LRRK2,MAD2L1,MERTK,MMP9,MUC1,NOD2,NRP1,PCDHGC3,PDCD1,PDK4,PIM1,PROK2,SYNE1,TNFSF18,TYRO3,UNG,XRCC2,ZC3H12A"} {"GO.ID":"GO:1900077","Term":"negative regulation of cellular response to insulin stimulus","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2316,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"APPL2,PID1,SOCS1"} {"GO.ID":"GO:0010659","Term":"cardiac muscle cell apoptotic process","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2317,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"CAMK2D,GCH1,JAK2"} {"GO.ID":"GO:0042119","Term":"neutrophil activation","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2318,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"CCL5,IL15,LILRA2"} {"GO.ID":"GO:0032212","Term":"positive regulation of telomere maintenance via telomerase","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2319,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"AURKB,GCH1,PKIB"} {"GO.ID":"GO:0002792","Term":"negative regulation of peptide secretion","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2320,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"CD74,CRHBP,GHRL"} {"GO.ID":"GO:0008206","Term":"bile acid metabolic process","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2321,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"ATP8B1,HSD3B7,OSBPL6"} {"GO.ID":"GO:0048821","Term":"erythrocyte development","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2322,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"ALAS1,BCL6,TAL1"} {"GO.ID":"GO:1902275","Term":"regulation of chromatin organization","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2323,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"BAZ1A,MKI67,TAL1"} {"GO.ID":"GO:0071825","Term":"protein-lipid complex organization","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2324,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"AGT,LPL,SOAT1"} {"GO.ID":"GO:0046677","Term":"response to antibiotic","Annotated":34,"Significant":3,"Expected":2.05,"Rank in p.value_classic":2325,"p.value_elim":0.3367,"p.value_classic":0.33816,"genes":"AOC3,CIITA,JAK2"} {"GO.ID":"GO:0072089","Term":"stem cell proliferation","Annotated":94,"Significant":7,"Expected":5.68,"Rank in p.value_classic":2328,"p.value_elim":0.33773,"p.value_classic":0.34009,"genes":"ABCB1,CDKN2C,KITLG,OVOL1,PIM1,SOX17,VEGFC"} {"GO.ID":"GO:0007283","Term":"spermatogenesis","Annotated":377,"Significant":25,"Expected":22.77,"Rank in p.value_classic":2350,"p.value_elim":0.33786,"p.value_classic":0.34256,"genes":"ADGB,BCL2L11,BCL6,DAZL,DMC1,HORMAD1,IGF2R,LIMK2,LRRK2,MERTK,OCA2,OVOL1,PIWIL4,PROK2,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TMEM119,TYRO3,ZMYND15"} {"GO.ID":"GO:0048870","Term":"cell motility","Annotated":1352,"Significant":109,"Expected":81.65,"Rank in p.value_classic":485,"p.value_elim":0.33829,"p.value_classic":0.0009,"genes":"ADAM8,ADORA3,AGT,AMOT,ANLN,APPL2,ASB2,ASCL2,ATP1B2,BCL6,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD274,CD300H,CD40,CD74,CDH5,CDK1,CEACAM1,CELSR1,CHRD,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,DAB1,DAB2,EDN1,ENPP2,EPHB3,FAM107A,FMNL2,FSCN1,GLIPR2,GLUL,GPR183,HBEGF,HGF,HSD3B7,ICAM1,IFITM1,IL12A,ITGA7,ITGB5,JAK2,KIF26A,KITLG,KLF4,KLRK1,LRATD1,LRP5,LRRK2,LYN,LYVE1,MCOLN2,MDGA1,MERTK,MIR503,MMP9,MTUS1,NLRP12,NOD2,NR4A3,NRCAM,NRP1,ONECUT2,P2RX4,PADI2,PARP9,PDE4B,PLXNA2,PML,PRKX,PTGER4,PTPRU,PXN,RAPGEF2,S1PR1,SDC2,SDC3,SELL,SEMA6B,SEPTIN4,SGPL1,SLAMF1,SLAMF8,SOX17,STAP1,STMN1,TBX21,TMSB10,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VCAM1,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0009611","Term":"response to wounding","Annotated":454,"Significant":35,"Expected":27.42,"Rank in p.value_classic":1295,"p.value_elim":0.33917,"p.value_classic":0.08134,"genes":"ADORA3,CASP7,CD40,CDK1,CEACAM1,CHMP4C,COMP,CX3CR1,DHFR,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,HBEGF,ITGB5,JAK2,KLF4,KREMEN1,LYN,LYVE1,MERTK,MYOF,NRP1,P2RX4,PLEK,PLSCR1,RTN4RL1,S100A10,SCARF1,SERPING1,SLC11A1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0032892","Term":"positive regulation of organic acid transport","Annotated":31,"Significant":6,"Expected":1.87,"Rank in p.value_classic":743,"p.value_elim":0.33949,"p.value_classic":0.00956,"genes":"ACSL1,DTNBP1,EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:1903322","Term":"positive regulation of protein modification by small protein conjugation or removal","Annotated":125,"Significant":9,"Expected":7.55,"Rank in p.value_classic":2329,"p.value_elim":0.33976,"p.value_classic":0.34247,"genes":"AMER1,FAM107A,LRRK2,NMI,NOD2,RIPK2,SEPTIN4,TANK,ZC3H12A"} {"GO.ID":"GO:0043500","Term":"muscle adaptation","Annotated":79,"Significant":6,"Expected":4.77,"Rank in p.value_classic":2330,"p.value_elim":0.34032,"p.value_classic":0.34249,"genes":"AGT,CAMK2D,EDN1,MYOZ2,NR4A3,P2RX4"} {"GO.ID":"GO:0000305","Term":"response to oxygen radical","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2331,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0099170","Term":"postsynaptic modulation of chemical synaptic transmission","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2332,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"GHRL,INA"} {"GO.ID":"GO:0010560","Term":"positive regulation of glycoprotein biosynthetic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2333,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"IL15,SOAT1"} {"GO.ID":"GO:0010667","Term":"negative regulation of cardiac muscle cell apoptotic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2334,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"GCH1,JAK2"} {"GO.ID":"GO:0003309","Term":"type B pancreatic cell differentiation","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2335,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"DLL1,SIDT2"} {"GO.ID":"GO:0141087","Term":"positive regulation of inflammasome-mediated signaling pathway","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2336,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"GBP2,GBP5"} {"GO.ID":"GO:0060561","Term":"apoptotic process involved in morphogenesis","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2337,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"BCL2L11,LRP5"} {"GO.ID":"GO:0035024","Term":"negative regulation of Rho protein signal transduction","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2338,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"BCL6,STMN1"} {"GO.ID":"GO:1903319","Term":"positive regulation of protein maturation","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2339,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"ADAM8,S100A10"} {"GO.ID":"GO:0050995","Term":"negative regulation of lipid catabolic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2340,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"HCAR2,PDE3B"} {"GO.ID":"GO:0048265","Term":"response to pain","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2341,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"GCH1,P2RX4"} {"GO.ID":"GO:0035336","Term":"long-chain fatty-acyl-CoA metabolic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2342,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"ACSL1,DGAT2"} {"GO.ID":"GO:0071280","Term":"cellular response to copper ion","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2343,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"CYP1A1,MT2A"} {"GO.ID":"GO:0042537","Term":"benzene-containing compound metabolic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2344,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"IDO1,IDO2"} {"GO.ID":"GO:0008209","Term":"androgen metabolic process","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2345,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"DHRS9,SGPL1"} {"GO.ID":"GO:0001832","Term":"blastocyst growth","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2346,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"GINS1,NCAPG2"} {"GO.ID":"GO:0071875","Term":"adrenergic receptor signaling pathway","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2347,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"PDE4B,RAPGEF2"} {"GO.ID":"GO:2000647","Term":"negative regulation of stem cell proliferation","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2348,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"CDKN2C,OVOL1"} {"GO.ID":"GO:1901201","Term":"regulation of extracellular matrix assembly","Annotated":20,"Significant":2,"Expected":1.21,"Rank in p.value_classic":2349,"p.value_elim":0.3414,"p.value_classic":0.34255,"genes":"AGT,ANTXR1"} {"GO.ID":"GO:0061900","Term":"glial cell activation","Annotated":49,"Significant":4,"Expected":2.96,"Rank in p.value_classic":2351,"p.value_elim":0.34153,"p.value_classic":0.34326,"genes":"CX3CR1,JAK2,LRRK2,STAP1"} {"GO.ID":"GO:0030865","Term":"cortical cytoskeleton organization","Annotated":49,"Significant":4,"Expected":2.96,"Rank in p.value_classic":2352,"p.value_elim":0.34153,"p.value_classic":0.34326,"genes":"ANLN,FMNL2,IQGAP3,PLEK"} {"GO.ID":"GO:0140962","Term":"multicellular organismal-level chemical homeostasis","Annotated":49,"Significant":4,"Expected":2.96,"Rank in p.value_classic":2353,"p.value_elim":0.34153,"p.value_classic":0.34326,"genes":"B2M,CTNS,EPAS1,SLC11A1"} {"GO.ID":"GO:0046888","Term":"negative regulation of hormone secretion","Annotated":49,"Significant":4,"Expected":2.96,"Rank in p.value_classic":2354,"p.value_elim":0.34153,"p.value_classic":0.34326,"genes":"CRHBP,EDN1,GHRL,OSM"} {"GO.ID":"GO:0140238","Term":"presynaptic endocytosis","Annotated":64,"Significant":5,"Expected":3.87,"Rank in p.value_classic":2355,"p.value_elim":0.34191,"p.value_classic":0.34388,"genes":"DNM1,ITSN1,LRRK2,STX1A,SYT1"} {"GO.ID":"GO:0031023","Term":"microtubule organizing center organization","Annotated":141,"Significant":10,"Expected":8.52,"Rank in p.value_classic":2358,"p.value_elim":0.34375,"p.value_classic":0.34664,"genes":"ATF5,BRCA1,CCNF,CDK1,CHMP4C,KIF11,NDC80,PCLAF,WDR62,XRCC2"} {"GO.ID":"GO:0014074","Term":"response to purine-containing compound","Annotated":110,"Significant":8,"Expected":6.64,"Rank in p.value_classic":2356,"p.value_elim":0.34379,"p.value_classic":0.34635,"genes":"CRHBP,P2RX4,P2RX7,RAPGEF2,STAT1,THBD,TLR7,XRN1"} {"GO.ID":"GO:0043534","Term":"blood vessel endothelial cell migration","Annotated":110,"Significant":8,"Expected":6.64,"Rank in p.value_classic":2357,"p.value_elim":0.34379,"p.value_classic":0.34635,"genes":"AMOT,CD40,CDH5,KLF4,MIR503,NRP1,P2RX4,VEGFC"} {"GO.ID":"GO:0120254","Term":"olefinic compound metabolic process","Annotated":95,"Significant":7,"Expected":5.74,"Rank in p.value_classic":2359,"p.value_elim":0.34766,"p.value_classic":0.35005,"genes":"CYP1A1,DAB2,DGAT2,DHRS3,DHRS9,EPHX1,PLB1"} {"GO.ID":"GO:0051961","Term":"negative regulation of nervous system development","Annotated":126,"Significant":9,"Expected":7.61,"Rank in p.value_classic":2360,"p.value_elim":0.34835,"p.value_classic":0.3511,"genes":"APPL2,ASCL2,B2M,DAB1,DYNLT1,FSTL4,NRP1,RAPGEF2,SEMA6B"} {"GO.ID":"GO:1901875","Term":"positive regulation of post-translational protein modification","Annotated":126,"Significant":9,"Expected":7.61,"Rank in p.value_classic":2361,"p.value_elim":0.34835,"p.value_classic":0.3511,"genes":"AMER1,FAM107A,LRRK2,NMI,NOD2,RIPK2,SEPTIN4,TANK,ZC3H12A"} {"GO.ID":"GO:0051962","Term":"positive regulation of nervous system development","Annotated":236,"Significant":16,"Expected":14.25,"Rank in p.value_classic":2362,"p.value_elim":0.34898,"p.value_classic":0.35274,"genes":"CX3CR1,CYSLTR1,EGR2,EPHB3,GHRL,HAPLN3,LTA,LYN,NRP1,PLXNA2,TGM2,THBS2,VCAN,VEGFC,WDR62,XRCC2"} {"GO.ID":"GO:0002768","Term":"immune response-regulating cell surface receptor signaling pathway","Annotated":266,"Significant":41,"Expected":16.07,"Rank in p.value_classic":160,"p.value_elim":0.349,"p.value_classic":2.6e-08,"genes":"ACOD1,APPL2,BANK1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CD28,CD38,CD40,CEACAM1,CLEC6A,CTLA4,CYLD,FCN1,FYB1,GBP1,HLA-A,HLA-DPB1,HLA-DQB1,HLA-DRB1,HLA-G,IFI35,ITK,KLRK1,LILRA2,LYN,NMI,NOD2,NR4A3,PDE4B,PLPP4,PLSCR1,RIPK2,SCIMP,STAP1,TICAM2,TLR5,TNFRSF21,ZC3H12A"} {"GO.ID":"GO:0040017","Term":"positive regulation of locomotion","Annotated":496,"Significant":43,"Expected":29.96,"Rank in p.value_classic":756,"p.value_elim":0.35087,"p.value_classic":0.01057,"genes":"ADAM8,AGT,ASCL2,BCL6,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CSF1,CX3CR1,CXCL10,DAB2,EDN1,ENPP2,FAM107A,GLIPR2,HBEGF,HGF,ICAM1,IL12A,JAK2,KITLG,LYN,LYVE1,MMP9,NR4A3,NRP1,ONECUT2,P2RX4,RAPGEF2,S1PR1,SEMA6B,SLAMF1,SUCNR1,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0002701","Term":"negative regulation of production of molecular mediator of immune response","Annotated":34,"Significant":7,"Expected":2.05,"Rank in p.value_classic":624,"p.value_elim":0.35115,"p.value_classic":0.00366,"genes":"BCL6,HLA-F,JAK3,NOD2,PARP3,SLAMF1,TBX21"} {"GO.ID":"GO:0046639","Term":"negative regulation of alpha-beta T cell differentiation","Annotated":22,"Significant":6,"Expected":1.33,"Rank in p.value_classic":530,"p.value_elim":0.35125,"p.value_classic":0.00154,"genes":"ASCL2,BCL6,JAK3,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:1901701","Term":"cellular response to oxygen-containing compound","Annotated":949,"Significant":86,"Expected":57.32,"Rank in p.value_classic":354,"p.value_elim":0.35245,"p.value_classic":0.00008,"genes":"ACOD1,AGT,APPL2,BRCA1,CARD16,CASP4,CASP7,CASTOR1,CCL7,CCNA2,CD274,CD40,CD80,CDC6,CDK1,CEACAM1,CMPK2,COLEC12,CRHBP,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,DGAT2,DHFR,DTNBP1,EDN1,GBP2,GBP3,GBP5,GCH1,GHRL,GNG2,GRAMD1B,HGF,HLA-DRB1,ICAM1,IL18BP,JAK2,JAK3,KLF4,KLRK1,LILRA2,LITAF,LPL,LRP5,LRRK2,LYN,MMP9,NCF1,NOD2,NR4A3,P2RX4,P2RX7,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLSCR4,PNPLA3,PPM1E,PTGER4,PXN,RAPGEF2,RIPK2,SBNO2,SCIMP,SESN3,SIDT2,SLC2A5,SOCS1,SRI,SSTR2,STAMBPL1,STAP1,STAT1,TESC,TGM2,TICAM2,TIFAB,VCAM1,XRN1,ZC3H12A"} {"GO.ID":"GO:0010658","Term":"striated muscle cell apoptotic process","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2366,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"CAMK2D,GCH1,JAK2"} {"GO.ID":"GO:1901016","Term":"regulation of potassium ion transmembrane transporter activity","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2367,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"ANK2,ATP1B2,KCNE5"} {"GO.ID":"GO:0042220","Term":"response to cocaine","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2368,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"CCNA2,CRHBP,TGM2"} {"GO.ID":"GO:0032781","Term":"positive regulation of ATP-dependent activity","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2369,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"ATP1B2,PLSCR1,UHRF1"} {"GO.ID":"GO:0046427","Term":"positive regulation of receptor signaling pathway via JAK-STAT","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2370,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"AGT,CCL5,JAK2"} {"GO.ID":"GO:0032570","Term":"response to progesterone","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2371,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"ACOD1,CD38,TYMS"} {"GO.ID":"GO:0048806","Term":"genitalia development","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2372,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"MERTK,TIFAB,TYRO3"} {"GO.ID":"GO:1904646","Term":"cellular response to amyloid-beta","Annotated":35,"Significant":3,"Expected":2.11,"Rank in p.value_classic":2373,"p.value_elim":0.35352,"p.value_classic":0.35501,"genes":"CASP4,ICAM1,VCAM1"} {"GO.ID":"GO:0015807","Term":"L-amino acid transport","Annotated":65,"Significant":5,"Expected":3.93,"Rank in p.value_classic":2374,"p.value_elim":0.35406,"p.value_classic":0.35606,"genes":"CTNS,DTNBP1,KCNJ10,SERINC5,SLC11A1"} {"GO.ID":"GO:0007606","Term":"sensory perception of chemical stimulus","Annotated":65,"Significant":5,"Expected":3.93,"Rank in p.value_classic":2375,"p.value_elim":0.35406,"p.value_classic":0.35606,"genes":"ASIC1,B2M,OR2I1P,PKD1L3,RTP4"} {"GO.ID":"GO:0034599","Term":"cellular response to oxidative stress","Annotated":221,"Significant":15,"Expected":13.35,"Rank in p.value_classic":2381,"p.value_elim":0.35426,"p.value_classic":0.35791,"genes":"AIFM2,ATP13A2,CDK1,DHFR,EDN1,GCH1,HGF,IL18BP,KLF4,LRRK2,MMP9,NCF1,PXN,VRK2,ZC3H12A"} {"GO.ID":"GO:0034198","Term":"cellular response to amino acid starvation","Annotated":50,"Significant":4,"Expected":3.02,"Rank in p.value_classic":2376,"p.value_elim":0.35548,"p.value_classic":0.35725,"genes":"ATF3,CASTOR1,FAS,SESN3"} {"GO.ID":"GO:0051293","Term":"establishment of spindle localization","Annotated":50,"Significant":4,"Expected":3.02,"Rank in p.value_classic":2377,"p.value_elim":0.35548,"p.value_classic":0.35725,"genes":"DYNLT1,MAD2L1,NDC80,NUSAP1"} {"GO.ID":"GO:0007193","Term":"adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway","Annotated":50,"Significant":4,"Expected":3.02,"Rank in p.value_classic":2378,"p.value_elim":0.35548,"p.value_classic":0.35725,"genes":"EDN1,GRM8,S1PR1,SSTR2"} {"GO.ID":"GO:0021885","Term":"forebrain cell migration","Annotated":50,"Significant":4,"Expected":3.02,"Rank in p.value_classic":2379,"p.value_elim":0.35548,"p.value_classic":0.35725,"genes":"DAB1,LRRK2,MDGA1,TYRO3"} {"GO.ID":"GO:0031529","Term":"ruffle organization","Annotated":50,"Significant":4,"Expected":3.02,"Rank in p.value_classic":2380,"p.value_elim":0.35548,"p.value_classic":0.35725,"genes":"ICAM1,PLEK,SNX10,STAP1"} {"GO.ID":"GO:0031333","Term":"negative regulation of protein-containing complex assembly","Annotated":127,"Significant":9,"Expected":7.67,"Rank in p.value_classic":2382,"p.value_elim":0.35698,"p.value_classic":0.35976,"genes":"CDH5,MEFV,PRRT2,PTGER4,SCIN,SPTBN4,STMN1,TMSB10,TRIM31"} {"GO.ID":"GO:0034763","Term":"negative regulation of transmembrane transport","Annotated":96,"Significant":7,"Expected":5.8,"Rank in p.value_classic":2384,"p.value_elim":0.35762,"p.value_classic":0.36005,"genes":"APPL2,CAMK2D,KCNE5,MMP9,PID1,SRI,TRDN"} {"GO.ID":"GO:0033028","Term":"myeloid cell apoptotic process","Annotated":33,"Significant":6,"Expected":1.99,"Rank in p.value_classic":796,"p.value_elim":0.36177,"p.value_classic":0.01299,"genes":"CCL5,CTSL,HCAR2,IRF7,KITLG,NOD2"} {"GO.ID":"GO:0140013","Term":"meiotic nuclear division","Annotated":138,"Significant":16,"Expected":8.33,"Rank in p.value_classic":738,"p.value_elim":0.36329,"p.value_classic":0.00904,"genes":"BCL2L11,CCNE2,DAZL,DMC1,EME1,HORMAD1,MEIKIN,NCAPH,NDC80,NPM2,NUF2,RAD54B,RAD54L,TDRD9,TOP2A,ZWINT"} {"GO.ID":"GO:0019228","Term":"neuronal action potential","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2385,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"P2RX4,SCN4B"} {"GO.ID":"GO:0030194","Term":"positive regulation of blood coagulation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2386,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"ENPP4,THBD"} {"GO.ID":"GO:1900048","Term":"positive regulation of hemostasis","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2387,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"ENPP4,THBD"} {"GO.ID":"GO:0009147","Term":"pyrimidine nucleoside triphosphate metabolic process","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2388,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CMPK2,TYMS"} {"GO.ID":"GO:0051988","Term":"regulation of attachment of spindle microtubules to kinetochore","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2389,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"AURKB,BIRC5"} {"GO.ID":"GO:1905207","Term":"regulation of cardiocyte differentiation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2390,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"DLL1,SOX17"} {"GO.ID":"GO:0032094","Term":"response to food","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2391,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CYP1A1,GHRL"} {"GO.ID":"GO:0032069","Term":"regulation of nuclease activity","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2392,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"OAS2,OAS3"} {"GO.ID":"GO:0034367","Term":"protein-containing complex remodeling","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2393,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"AGT,LPL"} {"GO.ID":"GO:2000001","Term":"regulation of DNA damage checkpoint","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2394,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"BRCA1,WDR76"} {"GO.ID":"GO:0010804","Term":"negative regulation of tumor necrosis factor-mediated signaling pathway","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2395,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CARD16,TANK"} {"GO.ID":"GO:0099558","Term":"maintenance of synapse structure","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2396,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CBLN3,ERC2"} {"GO.ID":"GO:0010664","Term":"negative regulation of striated muscle cell apoptotic process","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2397,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"GCH1,JAK2"} {"GO.ID":"GO:0008045","Term":"motor neuron axon guidance","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2398,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"EGR2,NRP1"} {"GO.ID":"GO:0032495","Term":"response to muramyl dipeptide","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2399,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"NOD2,RIPK2"} {"GO.ID":"GO:0042104","Term":"positive regulation of activated T cell proliferation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2400,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"IL12RB1,SLAMF1"} {"GO.ID":"GO:0042278","Term":"purine nucleoside metabolic process","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2401,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"ENPP4,PRTFDC1"} {"GO.ID":"GO:0086011","Term":"membrane repolarization during action potential","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2402,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"KCNE5,KCNJ2"} {"GO.ID":"GO:0032770","Term":"positive regulation of monooxygenase activity","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2403,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0034698","Term":"response to gonadotropin","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2404,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CCNA2,EDN1"} {"GO.ID":"GO:0046457","Term":"prostanoid biosynthetic process","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2405,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CD74,EDN1"} {"GO.ID":"GO:2000773","Term":"negative regulation of cellular senescence","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2406,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"BCL6,GCH1"} {"GO.ID":"GO:0070977","Term":"bone maturation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2407,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"SNX10,XYLT1"} {"GO.ID":"GO:0033622","Term":"integrin activation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2408,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"PLEK,PTGER4"} {"GO.ID":"GO:0001702","Term":"gastrulation with mouth forming second","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2409,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"AMOT,LRP5"} {"GO.ID":"GO:0007205","Term":"protein kinase C-activating G protein-coupled receptor signaling pathway","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2410,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CISH,EDN1"} {"GO.ID":"GO:0001516","Term":"prostaglandin biosynthetic process","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2411,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CD74,EDN1"} {"GO.ID":"GO:0072574","Term":"hepatocyte proliferation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2412,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CEACAM1,FGL1"} {"GO.ID":"GO:0072575","Term":"epithelial cell proliferation involved in liver morphogenesis","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2413,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CEACAM1,FGL1"} {"GO.ID":"GO:1902774","Term":"late endosome to lysosome transport","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2414,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CHMP4C,LRRK2"} {"GO.ID":"GO:0090023","Term":"positive regulation of neutrophil chemotaxis","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2415,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CD74,EDN1"} {"GO.ID":"GO:0060045","Term":"positive regulation of cardiac muscle cell proliferation","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2416,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CDK1,PIM1"} {"GO.ID":"GO:0071624","Term":"positive regulation of granulocyte chemotaxis","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2417,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"CD74,EDN1"} {"GO.ID":"GO:0045823","Term":"positive regulation of heart contraction","Annotated":21,"Significant":2,"Expected":1.27,"Rank in p.value_classic":2418,"p.value_elim":0.36371,"p.value_classic":0.3649,"genes":"EDN1,GCH1"} {"GO.ID":"GO:0030168","Term":"platelet activation","Annotated":109,"Significant":13,"Expected":6.58,"Rank in p.value_classic":811,"p.value_elim":0.36444,"p.value_classic":0.01411,"genes":"CD40,CEACAM1,COMP,F2RL3,FGL1,JAK2,LYN,MERTK,PLEK,PLSCR1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0043067","Term":"regulation of programmed cell death","Annotated":1245,"Significant":106,"Expected":75.19,"Rank in p.value_classic":374,"p.value_elim":0.36586,"p.value_classic":0.00015,"genes":"ADAM8,AGT,AIFM2,ATF3,ATF5,ATP13A2,AURKB,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,C3orf38,CAMK2D,CARD16,CASP4,CASP7,CCL5,CD274,CD28,CD38,CD40,CD74,CDH5,CDK1,COMP,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DEPTOR,DLL1,E2F1,EDN1,FAS,G0S2,GADD45B,GBP1,GBP2,GBP3,GBP5,GCH1,GHRL,GIMAP8,HCAR2,HELLS,HGF,HLA-G,HTRA1,ICAM1,IDO1,IFIT2,IFIT3,IGF2R,IL12A,IL31RA,IL7,IRF7,JAK2,JAK3,KITLG,KLF4,LAMP3,LRP5,LRRK2,LTA,LYN,MAD2L1,MERTK,MMP9,MUC1,MYBL2,NOD2,NRP1,P2RX7,PCDHGC3,PDCD1,PDK4,PIM1,PMAIP1,PML,PROK2,RAPGEF2,RIPK2,SCIN,SEPTIN4,STAT1,SYNE1,TGM2,TIFAB,TMEM109,TNFAIP8L3,TNFSF10,TNFSF18,TOP2A,TYRO3,UBD,UNG,XRCC2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0010639","Term":"negative regulation of organelle organization","Annotated":332,"Significant":25,"Expected":20.05,"Rank in p.value_classic":1652,"p.value_elim":0.36681,"p.value_classic":0.14977,"genes":"AURKB,BIRC5,BRCA1,BUB1B,CCNF,CDH5,CENPF,HGF,HORMAD1,LIMK2,LRRK2,MAD2L1,NDC80,NUF2,PRRT2,S1PR1,SCIN,SPC24,SPC25,SPTBN4,STMN1,TMSB10,TOP2A,XRN1,ZWINT"} {"GO.ID":"GO:0030073","Term":"insulin secretion","Annotated":144,"Significant":10,"Expected":8.7,"Rank in p.value_classic":2419,"p.value_elim":0.36818,"p.value_classic":0.37116,"genes":"CCL5,CD38,GHRL,HLA-DRB1,IL1RN,JAK2,LRP5,SIDT2,SRI,STX1A"} {"GO.ID":"GO:0140115","Term":"export across plasma membrane","Annotated":51,"Significant":4,"Expected":3.08,"Rank in p.value_classic":2420,"p.value_elim":0.36943,"p.value_classic":0.37123,"genes":"ABCB1,ABCG2,ATP1B2,KCNE5"} {"GO.ID":"GO:0061045","Term":"negative regulation of wound healing","Annotated":51,"Significant":4,"Expected":3.08,"Rank in p.value_classic":2421,"p.value_elim":0.36943,"p.value_classic":0.37123,"genes":"CEACAM1,EDN1,SERPING1,THBD"} {"GO.ID":"GO:0032720","Term":"negative regulation of tumor necrosis factor production","Annotated":51,"Significant":4,"Expected":3.08,"Rank in p.value_classic":2422,"p.value_elim":0.36943,"p.value_classic":0.37123,"genes":"GHRL,NOD2,SLAMF1,ZC3H12A"} {"GO.ID":"GO:1904263","Term":"positive regulation of TORC1 signaling","Annotated":51,"Significant":4,"Expected":3.08,"Rank in p.value_classic":2423,"p.value_elim":0.36943,"p.value_classic":0.37123,"genes":"CASTOR1,CTNS,PIM1,STAMBPL1"} {"GO.ID":"GO:0070050","Term":"neuron cellular homeostasis","Annotated":51,"Significant":4,"Expected":3.08,"Rank in p.value_classic":2424,"p.value_elim":0.36943,"p.value_classic":0.37123,"genes":"AIM2,ERC2,SV2B,TYRO3"} {"GO.ID":"GO:0014003","Term":"oligodendrocyte development","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2425,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"KCNJ10,LYN,OLIG1"} {"GO.ID":"GO:1905898","Term":"positive regulation of response to endoplasmic reticulum stress","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2426,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"AGR2,BCL2L11,PMAIP1"} {"GO.ID":"GO:0009712","Term":"catechol-containing compound metabolic process","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2427,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"EPAS1,GCH1,NPR1"} {"GO.ID":"GO:1903307","Term":"positive regulation of regulated secretory pathway","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2428,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"HLA-F,STX1A,SYT1"} {"GO.ID":"GO:0022616","Term":"DNA strand elongation","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2429,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"GINS1,MCM4,MCM7"} {"GO.ID":"GO:0031952","Term":"regulation of protein autophosphorylation","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2430,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"MVP,NLRP12,VEGFC"} {"GO.ID":"GO:0006584","Term":"catecholamine metabolic process","Annotated":36,"Significant":3,"Expected":2.17,"Rank in p.value_classic":2431,"p.value_elim":0.37029,"p.value_classic":0.37181,"genes":"EPAS1,GCH1,NPR1"} {"GO.ID":"GO:0045944","Term":"positive regulation of transcription by RNA polymerase II","Annotated":1016,"Significant":64,"Expected":61.36,"Rank in p.value_classic":2434,"p.value_elim":0.37067,"p.value_classic":0.3788,"genes":"ABLIM3,ASCL2,ATF3,ATF5,BACH1,BMAL2,BRCA1,CASZ1,CD28,CD40,CIITA,CXCL10,DAB2,DLL1,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,HGF,IL4I1,IRF1,IRF4,IRF7,JAK2,KLF4,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,PID1,PLSCR1,RELB,RIPK2,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SSBP3,STAT1,STAT2,TAL1,TBX21,TFEC,TLR7,TNFSF8,TOP2A,TOX2,UHRF1,ZC3H12A,ZNF395"} {"GO.ID":"GO:2000147","Term":"positive regulation of cell motility","Annotated":484,"Significant":42,"Expected":29.23,"Rank in p.value_classic":777,"p.value_elim":0.37253,"p.value_classic":0.01125,"genes":"ADAM8,AGT,ASCL2,BCL6,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CSF1,CX3CR1,CXCL10,DAB2,EDN1,ENPP2,FAM107A,GLIPR2,HBEGF,HGF,ICAM1,IL12A,JAK2,KITLG,LYN,LYVE1,MMP9,NR4A3,NRP1,ONECUT2,P2RX4,RAPGEF2,S1PR1,SEMA6B,SLAMF1,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0060993","Term":"kidney morphogenesis","Annotated":82,"Significant":6,"Expected":4.95,"Rank in p.value_classic":2432,"p.value_elim":0.37304,"p.value_classic":0.37531,"genes":"AGT,CTNS,GCNT3,LRRK2,PRKX,STAT1"} {"GO.ID":"GO:0046942","Term":"carboxylic acid transport","Annotated":236,"Significant":19,"Expected":14.25,"Rank in p.value_classic":1514,"p.value_elim":0.37421,"p.value_classic":0.1229,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ATP8B1,CEACAM1,CTNS,DTNBP1,EDN1,KCNJ10,LRP5,P2RX4,P2RX7,RBP7,SERINC5,SLC11A1,SLC16A10,SLC6A12,TNFRSF11A"} {"GO.ID":"GO:0048638","Term":"regulation of developmental growth","Annotated":256,"Significant":17,"Expected":15.46,"Rank in p.value_classic":2433,"p.value_elim":0.37444,"p.value_classic":0.37844,"genes":"AGR2,BCL2L11,CDK1,COLQ,CSF1,DLL1,EDN1,FSTL4,GHRL,IL7,NRCAM,NRP1,PIM1,SEMA6B,SGPL1,SPTBN4,SYT1"} {"GO.ID":"GO:0051249","Term":"regulation of lymphocyte activation","Annotated":425,"Significant":69,"Expected":25.67,"Rank in p.value_classic":59,"p.value_elim":0.37496,"p.value_classic":2.8e-14,"genes":"ADAM8,ASCL2,B2M,BANK1,BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CD83,CTLA4,CYLD,FGL1,FGL2,GPR183,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,JAK2,JAK3,KITLG,KLRK1,LAG3,LYN,MERTK,NOD2,PARP3,PDCD1LG2,RIPK2,SIT1,SLAMF1,SLAMF8,SOCS1,TBX21,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,VCAM1,ZC3H12A"} {"GO.ID":"GO:0060759","Term":"regulation of response to cytokine stimulus","Annotated":153,"Significant":25,"Expected":9.24,"Rank in p.value_classic":269,"p.value_elim":0.3751,"p.value_classic":4.8e-06,"genes":"CARD16,CASP4,CCL5,CD300LF,CD74,CSF1,CYLD,EDN1,IFIH1,IL1RN,IL7,IRF7,KLF4,NLRC5,OAS3,PADI2,PARP14,PARP9,RIPK2,STAP1,STAT2,TANK,TICAM2,VRK2,ZBP1"} {"GO.ID":"GO:0009749","Term":"response to glucose","Annotated":145,"Significant":10,"Expected":8.76,"Rank in p.value_classic":2435,"p.value_elim":0.37636,"p.value_classic":0.37937,"genes":"GHRL,GJD3,GLUL,HLA-DRB1,ICAM1,LPL,LRP5,NCF1,SIDT2,SRI"} {"GO.ID":"GO:0001764","Term":"neuron migration","Annotated":145,"Significant":10,"Expected":8.76,"Rank in p.value_classic":2436,"p.value_elim":0.37636,"p.value_classic":0.37937,"genes":"CELSR1,DAB1,KIF26A,MDGA1,NRCAM,NRP1,RAPGEF2,SEPTIN4,TYRO3,WDR62"} {"GO.ID":"GO:0045595","Term":"regulation of cell differentiation","Annotated":1267,"Significant":102,"Expected":76.52,"Rank in p.value_classic":518,"p.value_elim":0.37793,"p.value_classic":0.0014,"genes":"ADAM8,AGT,APPL2,ASCL2,B2M,BCL6,BHLHE41,BTN2A2,CASZ1,CD101,CD28,CD74,CD80,CD83,CDH5,CDK1,CDS1,CEACAM1,CHRD,CSF1,CTLA4,CX3CR1,CXCL10,CXCL9,CYLD,CYSLTR1,DAB1,DAB2,DLL1,DYNLT1,E2F1,EDN1,EGR2,FAXDC2,FGL2,FSTL4,GLIPR2,HAPLN3,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IFITM1,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,IRF7,JAK2,JAK3,KITLG,KLF4,LAG3,LBH,LILRB3,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MMD,MMP9,NRCAM,NRP1,OSM,PIM1,PLAAT4,PLXNA2,PRKX,RAPGEF2,RIPK2,S100A10,SCIN,SEMA6B,SLAMF8,SLC45A3,SOCS1,SOX17,STAT1,TAL1,TBX21,TESC,TGM2,TMEM119,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF21,VCAN,VEGFC,WDR62,XRCC2,ZC3H12A"} {"GO.ID":"GO:0003300","Term":"cardiac muscle hypertrophy","Annotated":67,"Significant":5,"Expected":4.05,"Rank in p.value_classic":2437,"p.value_elim":0.3784,"p.value_classic":0.38046,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0034766","Term":"negative regulation of monoatomic ion transmembrane transport","Annotated":67,"Significant":5,"Expected":4.05,"Rank in p.value_classic":2438,"p.value_elim":0.3784,"p.value_classic":0.38046,"genes":"CAMK2D,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0050764","Term":"regulation of phagocytosis","Annotated":79,"Significant":16,"Expected":4.77,"Rank in p.value_classic":305,"p.value_elim":0.37921,"p.value_classic":0.00002,"genes":"APPL2,C2,C3,C4A,C4B,CD300LF,DYSF,FCN1,IL15,IL15RA,MERTK,NOD2,PLSCR1,SLC11A1,STAP1,TGM2"} {"GO.ID":"GO:0071375","Term":"cellular response to peptide hormone stimulus","Annotated":246,"Significant":20,"Expected":14.86,"Rank in p.value_classic":1435,"p.value_elim":0.3799,"p.value_classic":0.10794,"genes":"AGT,APPL2,CCNA2,CDC6,CEACAM1,CRHBP,EDN1,GHRL,JAK2,JAK3,LYN,NR4A3,PDE3B,PDK4,PID1,PNPLA3,PXN,SESN3,SOCS1,STAT1"} {"GO.ID":"GO:0048545","Term":"response to steroid hormone","Annotated":257,"Significant":17,"Expected":15.52,"Rank in p.value_classic":2440,"p.value_elim":0.3806,"p.value_classic":0.38462,"genes":"ACOD1,BCL2L11,BRCA1,CD38,DAB2,EDN1,FAM107A,IL1RN,JAK2,LBH,NR4A3,PADI2,PAQR8,PTPRU,SLC12A3,SSTR2,TYMS"} {"GO.ID":"GO:0007051","Term":"spindle organization","Annotated":188,"Significant":16,"Expected":11.35,"Rank in p.value_classic":1420,"p.value_elim":0.38067,"p.value_classic":0.10429,"genes":"AURKB,BIRC5,CHMP4C,KIF11,KIF23,LIMK2,MYBL2,NDC80,NUF2,PARP3,PRC1,SPC25,STMN1,TACC2,UHRF1,WDR62"} {"GO.ID":"GO:0015849","Term":"organic acid transport","Annotated":237,"Significant":19,"Expected":14.31,"Rank in p.value_classic":1527,"p.value_elim":0.38077,"p.value_classic":0.12651,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ATP8B1,CEACAM1,CTNS,DTNBP1,EDN1,KCNJ10,LRP5,P2RX4,P2RX7,RBP7,SERINC5,SLC11A1,SLC16A10,SLC6A12,TNFRSF11A"} {"GO.ID":"GO:0042267","Term":"natural killer cell mediated cytotoxicity","Annotated":55,"Significant":12,"Expected":3.32,"Rank in p.value_classic":356,"p.value_elim":0.38079,"p.value_classic":0.00008,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL12A,KLRK1,LAG3,RNF19B,SLAMF6,SLAMF7"} {"GO.ID":"GO:0002228","Term":"natural killer cell mediated immunity","Annotated":55,"Significant":12,"Expected":3.32,"Rank in p.value_classic":357,"p.value_elim":0.38079,"p.value_classic":0.00008,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL12A,KLRK1,LAG3,RNF19B,SLAMF6,SLAMF7"} {"GO.ID":"GO:0033260","Term":"nuclear DNA replication","Annotated":39,"Significant":9,"Expected":2.36,"Rank in p.value_classic":441,"p.value_elim":0.38205,"p.value_classic":0.00042,"genes":"BCL6,CDC45,CDT1,FEN1,GINS1,MCM2,MCM4,MCM6,TK1"} {"GO.ID":"GO:0046849","Term":"bone remodeling","Annotated":72,"Significant":10,"Expected":4.35,"Rank in p.value_classic":765,"p.value_elim":0.38313,"p.value_classic":0.01091,"genes":"ADAM8,CD38,IL7,LRP5,P2RX7,PDK4,S1PR1,SNX10,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0097006","Term":"regulation of plasma lipoprotein particle levels","Annotated":52,"Significant":4,"Expected":3.14,"Rank in p.value_classic":2441,"p.value_elim":0.38335,"p.value_classic":0.38519,"genes":"AGT,DGAT2,LPL,SOAT1"} {"GO.ID":"GO:2000242","Term":"negative regulation of reproductive process","Annotated":52,"Significant":4,"Expected":3.14,"Rank in p.value_classic":2442,"p.value_elim":0.38335,"p.value_classic":0.38519,"genes":"HORMAD1,OVOL1,PKMYT1,ZWINT"} {"GO.ID":"GO:0043536","Term":"positive regulation of blood vessel endothelial cell migration","Annotated":52,"Significant":4,"Expected":3.14,"Rank in p.value_classic":2443,"p.value_elim":0.38335,"p.value_classic":0.38519,"genes":"CD40,NRP1,P2RX4,VEGFC"} {"GO.ID":"GO:0030154","Term":"cell differentiation","Annotated":3271,"Significant":230,"Expected":197.55,"Rank in p.value_classic":627,"p.value_elim":0.38457,"p.value_classic":0.00378,"genes":"ADAM8,ADAMTS15,ADGB,AGR2,AGT,ALAS1,AMER1,AMOT,ANK2,ANLN,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP1B2,ATP8B1,B2M,BATF2,BATF3,BCL6,BHLHE41,BTN2A2,C21orf91,C3,CASP7,CASZ1,CD101,CD28,CD38,CD74,CD80,CD83,CDH5,CDK1,CDKN2C,CDS1,CEACAM1,CELSR1,CENPF,CHAC1,CHRD,COMP,CSF1,CTLA4,CTSL,CX3CR1,CXADR,CXCL10,CXCL9,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DHFR,DHRS9,DLL1,DMC1,DTNBP1,DYNLT1,E2F1,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,EPOP,ESCO2,ETV7,FAXDC2,FGL2,FLT3LG,FSTL4,GADD45B,GHRL,GLDN,GLIPR2,GPR183,GRIN3A,GSTK1,HAPLN3,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,HORMAD1,HTRA1,ICAM1,IFITM1,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,INA,IRF1,IRF4,IRF7,ITGA7,ITGB5,ITK,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMB3,LBH,LILRB3,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MARVELD2,MDGA1,MERTK,MMD,MMP9,MTSS1,MYO7B,MYOZ2,NCAPG2,NPM2,NR4A3,NRCAM,NRN1,NRP1,NYAP2,OCA2,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,PAQR5,PAQR8,PCDH12,PIM1,PIWIL4,PLAAT3,PLAAT4,PLEK,PLXNA2,PML,PNPLA3,PRKX,PSMB8,PTGER4,PTPRU,RAPGEF2,RASGRF1,RELB,RIPK2,RSAD2,RTN4RL1,RXFP1,S100A10,S1PR1,SBNO2,SCARF1,SCIN,SDC2,SEMA6B,SEPTIN4,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC45A3,SLC4A7,SNX10,SOAT1,SOCS1,SOX17,SPATA9,SPTBN4,SSBP3,STAP1,STAT1,STEAP4,STMN1,SYNE1,SYT1,TAL1,TBATA,TBX21,TDRD9,TESC,TGM2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF8,TOP2A,TYMP,TYMS,TYRO3,UBD,VAMP5,VCAM1,VCAN,VEGFC,WDR62,WEE1,XRCC2,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0009725","Term":"response to hormone","Annotated":669,"Significant":46,"Expected":40.4,"Rank in p.value_classic":1859,"p.value_elim":0.38572,"p.value_classic":0.19617,"genes":"ACOD1,ACSL1,AGT,APPL2,BCL2L11,BRCA1,C2,CCNA2,CD38,CDC6,CEACAM1,CRHBP,CTSL,CTSS,DAB2,EDN1,EGR2,FAM107A,GHRL,GNG2,IL1RN,JAK2,JAK3,LBH,LRP5,LYN,NR4A3,PADI2,PAQR8,PDE3B,PDK4,PID1,PNPLA3,PTGER4,PTPRU,PXN,RXFP1,SESN3,SLC12A3,SOCS1,SSTR2,STAT1,STAT2,TNFRSF11A,TNFSF10,TYMS"} {"GO.ID":"GO:1902993","Term":"positive regulation of amyloid precursor protein catabolic process","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2445,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"GSAP,LYN"} {"GO.ID":"GO:0002043","Term":"blood vessel endothelial cell proliferation involved in sprouting angiogenesis","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2446,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"IL12A,MIR503"} {"GO.ID":"GO:1905562","Term":"regulation of vascular endothelial cell proliferation","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2447,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"GHRL,MIR503"} {"GO.ID":"GO:1903020","Term":"positive regulation of glycoprotein metabolic process","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2448,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"IL15,SOAT1"} {"GO.ID":"GO:0101023","Term":"vascular endothelial cell proliferation","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2449,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"GHRL,MIR503"} {"GO.ID":"GO:0019934","Term":"cGMP-mediated signaling","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2450,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"IRAG1,NPR1"} {"GO.ID":"GO:0051457","Term":"maintenance of protein location in nucleus","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2451,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"PML,SYNE1"} {"GO.ID":"GO:0002251","Term":"organ or tissue specific immune response","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2452,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"H2BC21,NOD2"} {"GO.ID":"GO:0007340","Term":"acrosome reaction","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2453,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"PLB1,SYT6"} {"GO.ID":"GO:0046339","Term":"diacylglycerol metabolic process","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2454,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"DGAT2,PLB1"} {"GO.ID":"GO:0051291","Term":"protein heterooligomerization","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2455,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"RRM2,SYT1"} {"GO.ID":"GO:0031579","Term":"membrane raft organization","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2456,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"COLEC12,S100A10"} {"GO.ID":"GO:1902254","Term":"negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2457,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"CD74,MUC1"} {"GO.ID":"GO:0051882","Term":"mitochondrial depolarization","Annotated":22,"Significant":2,"Expected":1.33,"Rank in p.value_classic":2458,"p.value_elim":0.38573,"p.value_classic":0.38696,"genes":"LRRK2,P2RX7"} {"GO.ID":"GO:0051321","Term":"meiotic cell cycle","Annotated":210,"Significant":23,"Expected":12.68,"Rank in p.value_classic":634,"p.value_elim":0.38652,"p.value_classic":0.00411,"genes":"BCL2L11,CCNE2,CDC25A,DAZL,DMC1,EDN1,EME1,EXO1,HORMAD1,MEIKIN,NCAPH,NDC80,NPM2,NUF2,OVOL1,PIWIL4,PKMYT1,RAD54B,RAD54L,TDRD9,TOP2A,XRCC2,ZWINT"} {"GO.ID":"GO:0048869","Term":"cellular developmental process","Annotated":3272,"Significant":230,"Expected":197.61,"Rank in p.value_classic":628,"p.value_elim":0.38653,"p.value_classic":0.00384,"genes":"ADAM8,ADAMTS15,ADGB,AGR2,AGT,ALAS1,AMER1,AMOT,ANK2,ANLN,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP1B2,ATP8B1,B2M,BATF2,BATF3,BCL6,BHLHE41,BTN2A2,C21orf91,C3,CASP7,CASZ1,CD101,CD28,CD38,CD74,CD80,CD83,CDH5,CDK1,CDKN2C,CDS1,CEACAM1,CELSR1,CENPF,CHAC1,CHRD,COMP,CSF1,CTLA4,CTSL,CX3CR1,CXADR,CXCL10,CXCL9,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DHFR,DHRS9,DLL1,DMC1,DTNBP1,DYNLT1,E2F1,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,EPOP,ESCO2,ETV7,FAXDC2,FGL2,FLT3LG,FSTL4,GADD45B,GHRL,GLDN,GLIPR2,GPR183,GRIN3A,GSTK1,HAPLN3,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,HORMAD1,HTRA1,ICAM1,IFITM1,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,INA,IRF1,IRF4,IRF7,ITGA7,ITGB5,ITK,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMB3,LBH,LILRB3,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MARVELD2,MDGA1,MERTK,MMD,MMP9,MTSS1,MYO7B,MYOZ2,NCAPG2,NPM2,NR4A3,NRCAM,NRN1,NRP1,NYAP2,OCA2,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,PAQR5,PAQR8,PCDH12,PIM1,PIWIL4,PLAAT3,PLAAT4,PLEK,PLXNA2,PML,PNPLA3,PRKX,PSMB8,PTGER4,PTPRU,RAPGEF2,RASGRF1,RELB,RIPK2,RSAD2,RTN4RL1,RXFP1,S100A10,S1PR1,SBNO2,SCARF1,SCIN,SDC2,SEMA6B,SEPTIN4,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC45A3,SLC4A7,SNX10,SOAT1,SOCS1,SOX17,SPATA9,SPTBN4,SSBP3,STAP1,STAT1,STEAP4,STMN1,SYNE1,SYT1,TAL1,TBATA,TBX21,TDRD9,TESC,TGM2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF8,TOP2A,TYMP,TYMS,TYRO3,UBD,VAMP5,VCAM1,VCAN,VEGFC,WDR62,WEE1,XRCC2,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0006950","Term":"response to stress","Annotated":3170,"Significant":302,"Expected":191.45,"Rank in p.value_classic":22,"p.value_elim":0.38694,"p.value_classic":1.2e-19,"genes":"ABCB1,ACOD1,ADAM8,ADGRE5,ADORA3,AGR2,AGT,AIFM2,AIM2,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APPL2,ARMT1,ASCL2,ASIC1,ATF3,ATP13A2,AURKB,B2M,BACH1,BATF2,BATF3,BCL2A1,BCL2L11,BCL6,BRCA1,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD163,CD274,CD28,CD300LF,CD38,CD40,CD74,CD83,CDC45,CDCA5,CDH5,CDK1,CEACAM1,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CIITA,CLEC10A,CLEC6A,CLSPN,COLEC12,COMP,CRHBP,CSF1,CTLA4,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DDX60,DERL3,DHFR,DMC1,DTL,DTNBP1,DTX3L,E2F1,EDN1,EEPD1,EME1,ENPP4,EPAS1,ESCO2,EXO1,F2RL3,FANCE,FAS,FBXO6,FCN1,FEN1,FGL1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GGT5,GHRL,GINS2,GLUL,GPR31,GRAMD4,GSDMA,GSDMD,GTSE1,H2BC21,HBEGF,HGF,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IRF1,IRF4,IRF7,ISG20,ITGB5,ITK,JAK2,JAK3,KARS1,KLF4,KLRK1,KREMEN1,LAG3,LGALS3BP,LILRA1,LILRA2,LILRB3,LPL,LRRK2,LTA,LY75,LYN,LYVE1,MAF,MAP1LC3C,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MMP25,MMP9,MSRB1,MT2A,MTSS1,MUC1,MYOF,NCF1,NEIL3,NLRC5,NLRP12,NMI,NOD2,NRP1,NUB1,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PLEK,PLSCR1,PMAIP1,PML,POLB,POLE2,PROK2,PTGER4,PXN,PYHIN1,RAB20,RAD54B,RAD54L,RALB,RASGRF1,RECQL4,RELB,RIPK2,RMI2,RNF19B,RNF213,RSAD2,RTN4RL1,RTP4,S100A10,SBNO2,SCARF1,SCIMP,SELENOP,SERINC5,SERPING1,SESN3,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SP140,SSTR2,STAP1,STAT1,STAT2,SUCNR1,TANK,TAP1,TFEC,THBD,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF8,TONSL,TOP2A,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VRK2,WDR76,XRCC2,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:1990868","Term":"response to chemokine","Annotated":73,"Significant":17,"Expected":4.41,"Rank in p.value_classic":228,"p.value_elim":0.38695,"p.value_classic":1.1e-06,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,LYN,PADI2,ZC3H12A"} {"GO.ID":"GO:1990869","Term":"cellular response to chemokine","Annotated":73,"Significant":17,"Expected":4.41,"Rank in p.value_classic":229,"p.value_elim":0.38695,"p.value_classic":1.1e-06,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,EDN1,LYN,PADI2,ZC3H12A"} {"GO.ID":"GO:1900026","Term":"positive regulation of substrate adhesion-dependent cell spreading","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2459,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"DAB2,NRP1,S100A10"} {"GO.ID":"GO:0034331","Term":"cell junction maintenance","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2460,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"CBLN3,ERC2,MTSS1"} {"GO.ID":"GO:0030857","Term":"negative regulation of epithelial cell differentiation","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2461,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"DLL1,MMP9,STAT1"} {"GO.ID":"GO:0042307","Term":"positive regulation of protein import into nucleus","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2462,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"CDK1,JAK2,ZC3H12A"} {"GO.ID":"GO:1904358","Term":"positive regulation of telomere maintenance via telomere lengthening","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2463,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"AURKB,GCH1,PKIB"} {"GO.ID":"GO:0003254","Term":"regulation of membrane depolarization","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2464,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"CAMK2D,LRRK2,P2RX7"} {"GO.ID":"GO:0033574","Term":"response to testosterone","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2465,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"EDN1,NCF1,XRN1"} {"GO.ID":"GO:0051294","Term":"establishment of spindle orientation","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2466,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"DYNLT1,MAD2L1,NDC80"} {"GO.ID":"GO:0048546","Term":"digestive tract morphogenesis","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2467,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"AGR2,EPHB3,SOX17"} {"GO.ID":"GO:0007520","Term":"myoblast fusion","Annotated":37,"Significant":3,"Expected":2.23,"Rank in p.value_classic":2468,"p.value_elim":0.38697,"p.value_classic":0.38853,"genes":"ADAMTS15,CXCL10,CXCL9"} {"GO.ID":"GO:0010595","Term":"positive regulation of endothelial cell migration","Annotated":99,"Significant":7,"Expected":5.98,"Rank in p.value_classic":2469,"p.value_elim":0.38763,"p.value_classic":0.39014,"genes":"AGT,CD40,EDN1,NRP1,P2RX4,VEGFC,ZC3H12A"} {"GO.ID":"GO:0032732","Term":"positive regulation of interleukin-1 production","Annotated":62,"Significant":13,"Expected":3.74,"Rank in p.value_classic":348,"p.value_elim":0.38829,"p.value_classic":0.00007,"genes":"AIM2,GBP5,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,RIPK2,S100A13,TLR8"} {"GO.ID":"GO:0006811","Term":"monoatomic ion transport","Annotated":853,"Significant":62,"Expected":51.52,"Rank in p.value_classic":1253,"p.value_elim":0.38897,"p.value_classic":0.07165,"genes":"ABCB1,ABCC11,ANK2,ANO4,APOL1,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,B2M,CACNA2D3,CALHM6,CAMK2D,CCL5,CCL8,CLIC5,CTNS,CTSS,CXCL10,CXCL11,CXCL9,CYSLTR1,EDN1,F2RL3,FLVCR2,GABRA3,GJD3,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LMTK2,LYN,MCOLN2,MMP9,OCA2,P2RX4,P2RX7,PDE4B,PKD1L3,PLPP4,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SPTBN4,SRI,STEAP4,TESC,TMEM109,TPCN1,TRDN,WWP1"} {"GO.ID":"GO:0048609","Term":"multicellular organismal reproductive process","Annotated":598,"Significant":38,"Expected":36.12,"Rank in p.value_classic":2475,"p.value_elim":0.38927,"p.value_classic":0.39549,"genes":"ADGB,APOL2,BCL2L11,BCL6,CXADR,CYP1A1,DAZL,DMC1,EDN1,GHRL,HORMAD1,IGF2R,LIMK2,LRRK2,MEIKIN,MERTK,NCAPH,NDC80,NPM2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PROK2,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TMEM119,TNFAIP6,TOP2A,TYRO3,ZMYND15"} {"GO.ID":"GO:0031342","Term":"negative regulation of cell killing","Annotated":26,"Significant":7,"Expected":1.57,"Rank in p.value_classic":471,"p.value_elim":0.38982,"p.value_classic":0.00068,"genes":"CEACAM1,CX3CR1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G"} {"GO.ID":"GO:0090231","Term":"regulation of spindle checkpoint","Annotated":20,"Significant":5,"Expected":1.21,"Rank in p.value_classic":672,"p.value_elim":0.39047,"p.value_classic":0.00575,"genes":"AURKB,BIRC5,MAD2L1,NDC80,ZWINT"} {"GO.ID":"GO:0006925","Term":"inflammatory cell apoptotic process","Annotated":20,"Significant":5,"Expected":1.21,"Rank in p.value_classic":673,"p.value_elim":0.39047,"p.value_classic":0.00575,"genes":"CCL5,CTSL,HCAR2,IRF7,NOD2"} {"GO.ID":"GO:0150076","Term":"neuroinflammatory response","Annotated":68,"Significant":5,"Expected":4.11,"Rank in p.value_classic":2470,"p.value_elim":0.39056,"p.value_classic":0.39266,"genes":"CX3CR1,JAK2,LRRK2,MMP9,STAP1"} {"GO.ID":"GO:0010822","Term":"positive regulation of mitochondrion organization","Annotated":68,"Significant":5,"Expected":4.11,"Rank in p.value_classic":2471,"p.value_elim":0.39056,"p.value_classic":0.39266,"genes":"BCL2L11,MMP9,NOD2,PMAIP1,TNFSF10"} {"GO.ID":"GO:0030500","Term":"regulation of bone mineralization","Annotated":68,"Significant":5,"Expected":4.11,"Rank in p.value_classic":2472,"p.value_elim":0.39056,"p.value_classic":0.39266,"genes":"ANKH,COMP,P2RX7,S1PR1,TMEM119"} {"GO.ID":"GO:0014897","Term":"striated muscle hypertrophy","Annotated":68,"Significant":5,"Expected":4.11,"Rank in p.value_classic":2473,"p.value_elim":0.39056,"p.value_classic":0.39266,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0051881","Term":"regulation of mitochondrial membrane potential","Annotated":68,"Significant":5,"Expected":4.11,"Rank in p.value_classic":2474,"p.value_elim":0.39056,"p.value_classic":0.39266,"genes":"CTNS,LRRK2,P2RX7,PID1,PMAIP1"} {"GO.ID":"GO:0007167","Term":"enzyme-linked receptor protein signaling pathway","Annotated":785,"Significant":53,"Expected":47.41,"Rank in p.value_classic":1916,"p.value_elim":0.39138,"p.value_classic":0.21353,"genes":"AGR2,AGT,APPL2,CD7,CDH5,CEACAM1,CHRD,COMP,CSF1,DAB2,DLL1,EPHB3,FSTL4,GAREM1,GFRA2,GHRL,HBEGF,HESX1,HGF,HTRA1,IGF2R,IL12A,IL31RA,ITGB5,JAK2,JAK3,LYN,MERTK,MIR503,MMP9,MTSS1,MVP,NPR1,NR4A3,NRP1,ONECUT2,PDK4,PID1,PML,PTPRU,PXN,RALB,RAPGEF2,REPS2,SESN3,SGPL1,SHCBP1,SOCS1,STAP1,STMN1,TNFAIP6,TYRO3,VEGFC"} {"GO.ID":"GO:0007596","Term":"blood coagulation","Annotated":174,"Significant":17,"Expected":10.51,"Rank in p.value_classic":1013,"p.value_elim":0.39181,"p.value_classic":0.03406,"genes":"CD40,CEACAM1,COMP,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,JAK2,LYN,MERTK,PLEK,PLSCR1,SERPING1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0046330","Term":"positive regulation of JNK cascade","Annotated":84,"Significant":6,"Expected":5.07,"Rank in p.value_classic":2477,"p.value_elim":0.39491,"p.value_classic":0.39724,"genes":"GADD45B,NCF1,NOD2,NRK,RIPK2,SLAMF1"} {"GO.ID":"GO:0045937","Term":"positive regulation of phosphate metabolic process","Annotated":574,"Significant":53,"Expected":34.67,"Rank in p.value_classic":512,"p.value_elim":0.39536,"p.value_classic":0.00128,"genes":"AGT,BANK1,C3,CCL5,CD40,CD74,CD80,CDH5,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRRK2,LYN,MERTK,MMD,MMP9,NCF1,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PID1,PLEK,RALB,RAPGEF2,RIPK2,SLC11A1,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC"} {"GO.ID":"GO:0010562","Term":"positive regulation of phosphorus metabolic process","Annotated":574,"Significant":53,"Expected":34.67,"Rank in p.value_classic":513,"p.value_elim":0.39536,"p.value_classic":0.00128,"genes":"AGT,BANK1,C3,CCL5,CD40,CD74,CD80,CDH5,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DTNBP1,EDN1,ENPP2,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRRK2,LYN,MERTK,MMD,MMP9,NCF1,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PID1,PLEK,RALB,RAPGEF2,RIPK2,SLC11A1,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TYRO3,VEGFC"} {"GO.ID":"GO:0051966","Term":"regulation of synaptic transmission, glutamatergic","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2478,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"DTNBP1,GRM8,LRRK2,SYT1"} {"GO.ID":"GO:0010803","Term":"regulation of tumor necrosis factor-mediated signaling pathway","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2479,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"CARD16,CASP4,CYLD,TANK"} {"GO.ID":"GO:0048008","Term":"platelet-derived growth factor receptor signaling pathway","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2480,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"JAK2,NR4A3,NRP1,SGPL1"} {"GO.ID":"GO:1901019","Term":"regulation of calcium ion transmembrane transporter activity","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2481,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"ANK2,CAMK2D,SRI,TRDN"} {"GO.ID":"GO:0030042","Term":"actin filament depolymerization","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2482,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"MICAL2,PLEK,SCIN,SPTBN4"} {"GO.ID":"GO:1990928","Term":"response to amino acid starvation","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2483,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"ATF3,CASTOR1,FAS,SESN3"} {"GO.ID":"GO:1902808","Term":"positive regulation of cell cycle G1/S phase transition","Annotated":53,"Significant":4,"Expected":3.2,"Rank in p.value_classic":2484,"p.value_elim":0.39724,"p.value_classic":0.39911,"genes":"CCNE2,CDC6,CYP1A1,RRM2"} {"GO.ID":"GO:0022412","Term":"cellular process involved in reproduction in multicellular organism","Annotated":292,"Significant":19,"Expected":17.64,"Rank in p.value_classic":2486,"p.value_elim":0.39778,"p.value_classic":0.40211,"genes":"ADGB,CXADR,DAZL,DMC1,EDN1,HORMAD1,MEIKIN,NCAPH,NDC80,NPM2,OCA2,PAQR5,PAQR8,SEPTIN4,TDRD9,TMEM119,TNFAIP6,TOP2A,ZMYND15"} {"GO.ID":"GO:0001933","Term":"negative regulation of protein phosphorylation","Annotated":260,"Significant":17,"Expected":15.7,"Rank in p.value_classic":2487,"p.value_elim":0.39916,"p.value_classic":0.40325,"genes":"AGT,CEACAM1,DEPTOR,DTNBP1,HGF,LRP5,LRRK2,LYN,MVP,NLRP12,PARP14,PID1,PKIB,PPM1E,SOCS1,WARS1,ZC3H12A"} {"GO.ID":"GO:0030856","Term":"regulation of epithelial cell differentiation","Annotated":116,"Significant":8,"Expected":7.01,"Rank in p.value_classic":2485,"p.value_elim":0.39937,"p.value_classic":0.4021,"genes":"CDH5,CEACAM1,DLL1,MAFF,MMP9,PLAAT4,PRKX,STAT1"} {"GO.ID":"GO:0030335","Term":"positive regulation of cell migration","Annotated":473,"Significant":41,"Expected":28.57,"Rank in p.value_classic":789,"p.value_elim":0.40071,"p.value_classic":0.01238,"genes":"ADAM8,AGT,ASCL2,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CSF1,CX3CR1,CXCL10,DAB2,EDN1,ENPP2,FAM107A,GLIPR2,HBEGF,HGF,ICAM1,IL12A,JAK2,KITLG,LYN,LYVE1,MMP9,NR4A3,NRP1,ONECUT2,P2RX4,RAPGEF2,S1PR1,SEMA6B,SLAMF1,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0001659","Term":"temperature homeostasis","Annotated":148,"Significant":10,"Expected":8.94,"Rank in p.value_classic":2488,"p.value_elim":0.40101,"p.value_classic":0.4041,"genes":"ACSL1,APPL2,EPAS1,G0S2,GHRL,IL15,IRF4,JAK2,NOD2,TNFRSF11A"} {"GO.ID":"GO:0007626","Term":"locomotory behavior","Annotated":148,"Significant":10,"Expected":8.94,"Rank in p.value_classic":2489,"p.value_elim":0.40101,"p.value_classic":0.4041,"genes":"ANKH,CTNS,DAB1,IDO1,KCNJ10,LRRK2,SELENOP,SOBP,SPTBN4,TAL1"} {"GO.ID":"GO:0050817","Term":"coagulation","Annotated":175,"Significant":17,"Expected":10.57,"Rank in p.value_classic":1032,"p.value_elim":0.40104,"p.value_classic":0.0357,"genes":"CD40,CEACAM1,COMP,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,JAK2,LYN,MERTK,PLEK,PLSCR1,SERPING1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0045927","Term":"positive regulation of growth","Annotated":196,"Significant":13,"Expected":11.84,"Rank in p.value_classic":2491,"p.value_elim":0.40108,"p.value_classic":0.40463,"genes":"AGR2,CD38,CDK1,CSF1,DLL1,EDN1,GHRL,HBEGF,IL7,NRP1,PIM1,SPTBN4,SYT1"} {"GO.ID":"GO:0043523","Term":"regulation of neuron apoptotic process","Annotated":196,"Significant":13,"Expected":11.84,"Rank in p.value_classic":2492,"p.value_elim":0.40108,"p.value_classic":0.40463,"genes":"ADAM8,ATP13A2,BCL2L11,CASP4,CASP7,CX3CR1,GCH1,JAK2,MYBL2,NRP1,PCDHGC3,TYRO3,XRCC2"} {"GO.ID":"GO:0007369","Term":"gastrulation","Annotated":164,"Significant":11,"Expected":9.9,"Rank in p.value_classic":2490,"p.value_elim":0.40126,"p.value_classic":0.40451,"genes":"AMOT,IL1RN,ITGA7,ITGB5,KLF4,LAMB3,LRP5,MMP9,NR4A3,SOX17,TAL1"} {"GO.ID":"GO:0014896","Term":"muscle hypertrophy","Annotated":69,"Significant":5,"Expected":4.17,"Rank in p.value_classic":2493,"p.value_elim":0.40271,"p.value_classic":0.40484,"genes":"AGT,CAMK2D,EDN1,NR4A3,P2RX4"} {"GO.ID":"GO:0071277","Term":"cellular response to calcium ion","Annotated":69,"Significant":5,"Expected":4.17,"Rank in p.value_classic":2494,"p.value_elim":0.40271,"p.value_classic":0.40484,"genes":"CAMK2D,CRHBP,EDN1,SYT1,SYT6"} {"GO.ID":"GO:0032481","Term":"positive regulation of type I interferon production","Annotated":69,"Significant":11,"Expected":4.17,"Rank in p.value_classic":575,"p.value_elim":0.40345,"p.value_classic":0.00266,"genes":"IFIH1,IRF1,IRF7,OAS2,OAS3,RIPK2,STAT1,TANK,TICAM2,TLR7,TLR8"} {"GO.ID":"GO:0044319","Term":"wound healing, spreading of cells","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2495,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"CEACAM1,HBEGF,ITGB5"} {"GO.ID":"GO:0048066","Term":"developmental pigmentation","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2496,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"BCL2L11,KITLG,OCA2"} {"GO.ID":"GO:0043303","Term":"mast cell degranulation","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2497,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"LYN,NR4A3,S100A13"} {"GO.ID":"GO:0090505","Term":"epiboly involved in wound healing","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2498,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"CEACAM1,HBEGF,ITGB5"} {"GO.ID":"GO:0043516","Term":"regulation of DNA damage response, signal transduction by p53 class mediator","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2499,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"CD74,PMAIP1,PYHIN1"} {"GO.ID":"GO:0021872","Term":"forebrain generation of neurons","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2500,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"B2M,NRP1,RAPGEF2"} {"GO.ID":"GO:0098815","Term":"modulation of excitatory postsynaptic potential","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2501,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"LRRK2,STX1A,SYNE1"} {"GO.ID":"GO:0090049","Term":"regulation of cell migration involved in sprouting angiogenesis","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2502,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"KLF4,MIR503,NRP1"} {"GO.ID":"GO:0006862","Term":"nucleotide transport","Annotated":38,"Significant":3,"Expected":2.3,"Rank in p.value_classic":2503,"p.value_elim":0.40354,"p.value_classic":0.40514,"genes":"ABCC11,ANKH,P2RX7"} {"GO.ID":"GO:0006631","Term":"fatty acid metabolic process","Annotated":293,"Significant":19,"Expected":17.7,"Rank in p.value_classic":2504,"p.value_elim":0.40363,"p.value_classic":0.40798,"genes":"ACOT4,ACSL1,APPL2,BRCA1,C3,CD74,CEACAM1,CYP1A1,EDN1,EPHX1,GGT5,LPL,LTC4S,NAAA,NR4A3,PDK4,PNPLA3,SGPL1,SLC45A3"} {"GO.ID":"GO:0032508","Term":"DNA duplex unwinding","Annotated":75,"Significant":13,"Expected":4.53,"Rank in p.value_classic":451,"p.value_elim":0.40374,"p.value_classic":0.0005,"genes":"CDC45,CHTF18,DSCC1,GINS1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RAD54B,RECQL4,TOP2A"} {"GO.ID":"GO:0030036","Term":"actin cytoskeleton organization","Annotated":618,"Significant":39,"Expected":37.32,"Rank in p.value_classic":2524,"p.value_elim":0.40448,"p.value_classic":0.41087,"genes":"AMOT,ANLN,ANTXR1,ASB2,BCL6,CELSR1,CXADR,DTNBP1,EDN1,FAM107A,FGD5,FMNL2,FRMD3,FSCN1,GHRL,IQGAP3,ITGB5,JAK2,LIMK2,MARCKSL1,MICAL2,MRAS,MSRB1,MTSS1,MYO7B,MYOZ2,NRP1,PLEK,PPM1E,PSTPIP2,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10,XIRP1"} {"GO.ID":"GO:0046649","Term":"lymphocyte activation","Annotated":661,"Significant":91,"Expected":39.92,"Rank in p.value_classic":62,"p.value_elim":0.40473,"p.value_classic":5.5e-14,"genes":"ADAM8,ASCL2,B2M,BANK1,BCL6,BTN2A2,BTN3A1,CCL5,CD1C,CD274,CD28,CD38,CD40,CD7,CD74,CD80,CD83,CEACAM1,CTLA4,CTSL,CXADR,CYLD,DLL1,EXO1,FGL1,FGL2,GPR183,HELLS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,ITK,JAK2,JAK3,KITLG,KLRK1,LAG3,LYN,MERTK,NOD2,P2RX7,PARP3,PDCD1LG2,PSMB10,PTGER4,RELB,RIPK2,RSAD2,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SOCS1,TBX21,TICAM2,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,TYRO3,UNG,VCAM1,ZC3H12A"} {"GO.ID":"GO:0023051","Term":"regulation of signaling","Annotated":2851,"Significant":209,"Expected":172.19,"Rank in p.value_classic":478,"p.value_elim":0.40504,"p.value_classic":0.00077,"genes":"ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,APOL3,APPL2,ASIC1,ATF3,AURKB,BANK1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,C3,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CEACAM1,CHAC1,CHRD,CIBAR1,CISH,CLEC6A,CRHBP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CYLD,DAB1,DAB2,DDX60,DEPTOR,DHRS3,DKK2,DLGAP3,DLL1,DNM1,DTNBP1,DYNLT1,DYSF,EDA,EDN1,EGR2,ERC2,F2RL3,FAM107A,FAM13A,FAS,FGD5,FSTL4,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GBP7,GHRL,GLIPR2,GPR183,GRAMD4,GRIN3A,GRM8,HBEGF,HCAR2,HELLS,HGF,HLA-DRB1,HLA-G,HTRA1,ICAM1,IFI35,IFIT5,IFT122,IL12A,IL1RN,IL7,INA,IQGAP3,IRF1,IRF4,IRF7,ITSN1,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KREMEN1,LBH,LILRA2,LITAF,LRP5,LRRK2,LYN,MAD2L1,MCF2L,MCTP2,MEFV,MIR503,MMP9,MUC1,MVP,MYOF,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP9,PDE3B,PDE4B,PID1,PIM1,PLEK,PLSCR1,PMAIP1,PML,PRRT2,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RGS18,RIPK2,RNF213,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SESN3,SIDT2,SLAMF1,SLC20A1,SOCS1,SOX17,SRI,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SV2B,SYNE1,SYT1,TAGAP,TANK,TGM2,TICAM2,TIFA,TIFAB,TLR7,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFSF10,TRABD2A,TRIM22,TRIM31,TSPAN15,TYRO3,UBD,VEGFC,VRK2,WDR76,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0048709","Term":"oligodendrocyte differentiation","Annotated":85,"Significant":6,"Expected":5.13,"Rank in p.value_classic":2505,"p.value_elim":0.40584,"p.value_classic":0.4082,"genes":"CDKN2C,KCNJ10,LYN,OLIG1,SLC45A3,TNFRSF21"} {"GO.ID":"GO:0010033","Term":"response to organic substance","Annotated":2130,"Significant":213,"Expected":128.64,"Rank in p.value_classic":52,"p.value_elim":0.40662,"p.value_classic":2.8e-15,"genes":"ACOD1,ACSL1,AGR2,AGT,AIM2,ALAS1,ANK2,APPL2,ASIC1,ATF3,B2M,BCL2L11,BRCA1,C2,C4B,CALCOCO2,CARD16,CASP4,CASP7,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD274,CD300LF,CD38,CD40,CD74,CD80,CD83,CDC6,CDK1,CDT1,CEACAM1,CHAC1,CIITA,CMPK2,COLEC12,COMP,CRHBP,CSF1,CSF2RB,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,DAB2,DERL3,DGAT2,DHFR,DTNBP1,EDN1,EGR2,EPHX1,FAM107A,FAS,FBXO6,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GHRL,GJD3,GLUL,GNG2,GPR31,GRAMD1B,GRIN3A,HELLS,HLA-DPA1,HLA-DRB1,ICAM1,IDO1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IQGAP3,IRF1,IRF7,JAK2,JAK3,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MCM2,MEFV,MMP9,MRAS,MT2A,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,NUB1,OAS2,OAS3,OPTN,OSM,P2RX4,P2RX7,PADI2,PAQR8,PARP14,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLSCR1,PLSCR4,PMAIP1,PML,PNPLA3,POLB,PPM1E,PTGER4,PTPRU,PXN,PYHIN1,RAB20,RALB,RAPGEF2,RELB,RIPK2,RUFY4,RXFP1,SBNO2,SCIMP,SELL,SESN3,SIDT2,SLC11A1,SLC12A3,SLC2A5,SNX10,SOCS1,SOX17,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,TANK,TAP2,TBX21,TESC,TGM2,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR7,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TYMS,UBD,VCAM1,VEGFC,VRK2,XAF1,XRN1,ZBP1,ZC3H12A"} {"GO.ID":"GO:0022408","Term":"negative regulation of cell-cell adhesion","Annotated":156,"Significant":28,"Expected":9.42,"Rank in p.value_classic":193,"p.value_elim":0.40731,"p.value_classic":1.8e-07,"genes":"ASCL2,BCL6,BTN2A2,CD274,CD74,CD80,CEACAM1,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL1RN,IL4I1,IRF1,JAK2,JAK3,KLF4,LAG3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,ZC3H12A"} {"GO.ID":"GO:0018904","Term":"ether metabolic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2506,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"EPHX1,PLAAT3"} {"GO.ID":"GO:0030204","Term":"chondroitin sulfate metabolic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2507,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"DSE,XYLT1"} {"GO.ID":"GO:0034391","Term":"regulation of smooth muscle cell apoptotic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2508,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"EDN1,IL12A"} {"GO.ID":"GO:0045948","Term":"positive regulation of translational initiation","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2509,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CCL5,DAZL"} {"GO.ID":"GO:0038095","Term":"Fc-epsilon receptor signaling pathway","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2510,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"LYN,NR4A3"} {"GO.ID":"GO:0061098","Term":"positive regulation of protein tyrosine kinase activity","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2511,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"AGT,NCF1"} {"GO.ID":"GO:0010661","Term":"positive regulation of muscle cell apoptotic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2512,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CAMK2D,IL12A"} {"GO.ID":"GO:0050857","Term":"positive regulation of antigen receptor-mediated signaling pathway","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2513,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CYLD,STAP1"} {"GO.ID":"GO:0050820","Term":"positive regulation of coagulation","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2514,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"ENPP4,THBD"} {"GO.ID":"GO:0050650","Term":"chondroitin sulfate proteoglycan biosynthetic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2515,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"DSE,XYLT1"} {"GO.ID":"GO:1900746","Term":"regulation of vascular endothelial growth factor signaling pathway","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2516,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"DLL1,IL12A"} {"GO.ID":"GO:1903306","Term":"negative regulation of regulated secretory pathway","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2517,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CEACAM1,HLA-F"} {"GO.ID":"GO:0050927","Term":"positive regulation of positive chemotaxis","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2518,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"S1PR1,VEGFC"} {"GO.ID":"GO:0008299","Term":"isoprenoid biosynthetic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2519,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CYP1A1,DHRS9"} {"GO.ID":"GO:0008207","Term":"C21-steroid hormone metabolic process","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2520,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"DAB2,DHRS9"} {"GO.ID":"GO:0072576","Term":"liver morphogenesis","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2521,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"CEACAM1,FGL1"} {"GO.ID":"GO:0035767","Term":"endothelial cell chemotaxis","Annotated":23,"Significant":2,"Expected":1.39,"Rank in p.value_classic":2522,"p.value_elim":0.40741,"p.value_classic":0.40867,"genes":"NRP1,P2RX4"} {"GO.ID":"GO:0007229","Term":"integrin-mediated signaling pathway","Annotated":101,"Significant":7,"Expected":6.1,"Rank in p.value_classic":2523,"p.value_elim":0.40766,"p.value_classic":0.41023,"genes":"CEACAM1,FYB1,ITGA7,ITGB5,NRP1,PLEK,TSPAN32"} {"GO.ID":"GO:0051239","Term":"regulation of multicellular organismal process","Annotated":2358,"Significant":230,"Expected":142.41,"Rank in p.value_classic":50,"p.value_elim":0.40775,"p.value_classic":2.3e-15,"genes":"ACOD1,ACSL1,ADAM8,ADORA3,AGT,AIM2,AMOT,ANK2,ANKH,APPL2,ASCL2,ATP1B2,B2M,BANK1,BCL2L11,BCL6,BHLHE41,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CCL5,CD101,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CEACAM1,CLEC6A,CLEC9A,COMP,CRHBP,CSF1,CTLA4,CX3CR1,CXADR,CXCL10,CYLD,CYSLTR1,DAB1,DAB2,DHRS3,DLGAP3,DLL1,DYNLT1,E2F2,EDN1,EGR2,ENPP2,ENPP4,EPAS1,EPHB3,FAXDC2,FCN1,FGL1,FGL2,FSTL4,G0S2,GBP1,GBP5,GBP7,GCH1,GHRL,GJD3,GLIPR2,GLUL,GPR183,GSDMD,HAPLN3,HAVCR1,HBEGF,HCAR2,HESX1,HGF,HLA-A,HLA-B,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KARS1,KCNE5,KCNJ2,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LILRA2,LILRB3,LITAF,LPL,LRRK2,LTA,LYN,MAF,MAFF,MCOLN2,MEFV,MERTK,MIR503,MMP9,NCF1,NLRP12,NMI,NOD2,NPR1,NR4A3,NRP1,OAS2,OAS3,OSM,P2RX4,P2RX7,PARP3,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PIM1,PLAAT4,PLEK,PLSCR1,PLXNA2,PML,PRKX,PROK2,PTGER4,RAPGEF2,RELB,RIPK2,RSAD2,S100A10,S100A13,S1PR1,SCIMP,SCIN,SCN4B,SEMA6B,SERPING1,SGPL1,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SOCS1,SOX17,SPTBN4,SRI,STAP1,STAT1,STX1A,SYNE1,TAL1,TANK,TBX21,TESC,TGM2,THBD,THBS2,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TRDN,TSPAN32,TYMP,TYRO3,VCAM1,VCAN,VEGFC,WARS1,WDR62,XAF1,XRCC2,ZC3H12A"} {"GO.ID":"GO:0030098","Term":"lymphocyte differentiation","Annotated":356,"Significant":45,"Expected":21.5,"Rank in p.value_classic":245,"p.value_elim":0.40778,"p.value_classic":1.9e-06,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CD28,CD74,CD80,CD83,CTLA4,CTSL,CYLD,DLL1,FGL2,GPR183,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL15,IL15RA,IL27,IL4I1,IL7,IRF1,IRF4,ITK,JAK3,LAG3,MERTK,PTGER4,RELB,RIPK2,RSAD2,SLAMF1,SLAMF6,SLAMF8,SOCS1,TBX21,TNFSF13B,TNFSF8,TYRO3,VCAM1,ZC3H12A"} {"GO.ID":"GO:0034220","Term":"monoatomic ion transmembrane transport","Annotated":693,"Significant":52,"Expected":41.85,"Rank in p.value_classic":1181,"p.value_elim":0.40782,"p.value_classic":0.06031,"genes":"ABCB1,ABCC11,ANK2,ANO4,APOL1,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,CACNA2D3,CALHM6,CAMK2D,CLIC5,CTNS,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,GABRA3,GJD3,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MCOLN2,MMP9,OCA2,P2RX4,P2RX7,PDE4B,PKD1L3,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SRI,TESC,TMEM109,TPCN1,TRDN,WWP1"} {"GO.ID":"GO:0050730","Term":"regulation of peptidyl-tyrosine phosphorylation","Annotated":182,"Significant":29,"Expected":10.99,"Rank in p.value_classic":238,"p.value_elim":0.40799,"p.value_classic":1.4e-06,"genes":"AGT,BANK1,CCL5,CD40,CD74,CD80,CLEC6A,ENPP2,HBEGF,HGF,IL12A,IL15,IL22RA2,IL31RA,IL7,JAK2,KITLG,LYN,MVP,NCF1,NOD2,NRP1,OSM,PARP14,PARP9,RIPK2,SOCS1,TNFRSF14,TNFSF18"} {"GO.ID":"GO:0033993","Term":"response to lipid","Annotated":720,"Significant":79,"Expected":43.48,"Rank in p.value_classic":189,"p.value_elim":0.4091,"p.value_classic":1.3e-07,"genes":"ACOD1,ACSL1,ALAS1,BCL2L11,BRCA1,C2,CARD16,CASP7,CCNA2,CD274,CD38,CD40,CD80,CMPK2,CRHBP,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,DAB2,DGAT2,EDN1,FAM107A,GBP2,GBP3,GBP5,GCH1,GNG2,GRAMD1B,IDO1,IGF2R,IL12A,IL12RB2,IL18BP,IL1RN,JAK2,KLF4,KLRK1,LBH,LILRA2,LITAF,LPL,LTA,LYN,MMP9,NCF1,NOD2,NR4A3,P2RX7,PADI2,PAQR8,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PLSCR4,PPM1E,PTGER4,PTPRU,RIPK2,SBNO2,SCIMP,SLC11A1,SLC12A3,SSTR2,STAP1,TESC,THBD,TICAM2,TIFAB,TNFRSF11A,TYMS,VCAM1,XRN1,ZC3H12A"} {"GO.ID":"GO:0006469","Term":"negative regulation of protein kinase activity","Annotated":149,"Significant":10,"Expected":9,"Rank in p.value_classic":2525,"p.value_elim":0.40924,"p.value_classic":0.41235,"genes":"AGT,CEACAM1,DEPTOR,DTNBP1,LRP5,LYN,MVP,PKIB,PPM1E,WARS1"} {"GO.ID":"GO:0098916","Term":"anterograde trans-synaptic signaling","Annotated":542,"Significant":38,"Expected":32.73,"Rank in p.value_classic":1830,"p.value_elim":0.40948,"p.value_classic":0.18839,"genes":"ADORA3,AKAP7,ASIC1,CADPS2,CD38,COLQ,CRHBP,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GABRA3,GHRL,GRIN3A,GRM8,HRH2,INA,INSYN2A,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,P2RX4,P2RX7,PRRT2,RAPGEF2,RASGRF1,STX11,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0007268","Term":"chemical synaptic transmission","Annotated":542,"Significant":38,"Expected":32.73,"Rank in p.value_classic":1831,"p.value_elim":0.40948,"p.value_classic":0.18839,"genes":"ADORA3,AKAP7,ASIC1,CADPS2,CD38,COLQ,CRHBP,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GABRA3,GHRL,GRIN3A,GRM8,HRH2,INA,INSYN2A,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,P2RX4,P2RX7,PRRT2,RAPGEF2,RASGRF1,STX11,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0070663","Term":"regulation of leukocyte proliferation","Annotated":215,"Significant":41,"Expected":12.99,"Rank in p.value_classic":97,"p.value_elim":0.41051,"p.value_classic":3.5e-11,"genes":"BCL6,BTN2A2,CCL5,CCL8,CD274,CD28,CD38,CD74,CD80,CSF1,CSF2RB,CTLA4,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,PDCD1LG2,RIPK2,SLAMF1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0010718","Term":"positive regulation of epithelial to mesenchymal transition","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2526,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"ADAM8,AGT,DAB2,GLIPR2"} {"GO.ID":"GO:0031016","Term":"pancreas development","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2527,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"DLL1,DNAAF1,ONECUT2,SIDT2"} {"GO.ID":"GO:0010812","Term":"negative regulation of cell-substrate adhesion","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2528,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"BCL6,FAM107A,GBP1,MIR503"} {"GO.ID":"GO:0014823","Term":"response to activity","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2529,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"AGT,CDK1,EDN1,SCO2"} {"GO.ID":"GO:0032210","Term":"regulation of telomere maintenance via telomerase","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2530,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"AURKB,GCH1,PKIB,XRN1"} {"GO.ID":"GO:1901379","Term":"regulation of potassium ion transmembrane transport","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2531,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"ANK2,ATP1B2,KCNE5,KCNJ2"} {"GO.ID":"GO:0051653","Term":"spindle localization","Annotated":54,"Significant":4,"Expected":3.26,"Rank in p.value_classic":2532,"p.value_elim":0.41108,"p.value_classic":0.41297,"genes":"DYNLT1,MAD2L1,NDC80,NUSAP1"} {"GO.ID":"GO:0006650","Term":"glycerophospholipid metabolic process","Annotated":262,"Significant":17,"Expected":15.82,"Rank in p.value_classic":2533,"p.value_elim":0.41158,"p.value_classic":0.41571,"genes":"CDS1,CISH,ENPP2,LCLAT1,NAAA,PCYT1A,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLSCR1,PNPLA3,SERINC5,SOCS1,TMEM150A,TNFAIP8L3"} {"GO.ID":"GO:0035556","Term":"intracellular signal transduction","Annotated":2292,"Significant":180,"Expected":138.43,"Rank in p.value_classic":344,"p.value_elim":0.41246,"p.value_classic":0.00006,"genes":"ADAM8,AGT,AIM2,AKAP7,AMOT,ANK2,APOL3,ASB2,ATF3,AURKB,BANK1,BCL2A1,BCL2L11,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCRL2,CD28,CD40,CD74,CD80,CDC45,CDC6,CDK1,CDT1,CEACAM1,CELSR1,CENPF,CHAC1,CHMP4C,CISH,CLEC6A,CLSPN,CSF1,CTNS,CX3CR1,CXCR3,CYLD,DAB1,DAB2,DEPDC7,DEPTOR,DTL,DTX3L,E2F1,E2F2,EDA,EDN1,EME1,F2RL3,FAM13A,FAS,FBXO6,FGD5,GADD45B,GAREM1,GBP1,GBP7,GHRL,GLIPR2,GPR183,GTSE1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-G,HORMAD1,ICAM1,IFI35,IFIT5,IL31RA,IQGAP3,IRAG1,ITK,ITSN1,JAK2,JAK3,KARS1,KITLG,LBH,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MCOLN2,MCTP2,MERTK,MIR503,MMP9,MRAS,MUC1,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRK,NRP1,NUCB1,NUF2,NYAP2,OPTN,ORC1,OSM,P2RX4,P2RX7,PARP9,PDE3B,PDE4B,PIM1,PLCD3,PLEK,PMAIP1,PML,POLB,PTGER4,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,RHEBL1,RIPK2,S100A13,SCIMP,SECTM1,SEPTIN4,SESN3,SLAMF1,SLC20A1,SOCS1,SPC24,SPC25,STAMBPL1,STAT1,STMN1,TAGAP,TANK,TGM2,TICAM2,TICRR,TIFA,TIFAB,TLR7,TLR8,TMEM109,TNFAIP8L3,TNFRSF11A,TNFSF10,TPCN1,TRIM22,TYRO3,UBD,VCAM1,VRK2,WDR76,ZC3H12A,ZWINT"} {"GO.ID":"GO:0032147","Term":"activation of protein kinase activity","Annotated":70,"Significant":5,"Expected":4.23,"Rank in p.value_classic":2534,"p.value_elim":0.41483,"p.value_classic":0.41698,"genes":"AGT,CCL5,CLSPN,JAK2,SLC11A1"} {"GO.ID":"GO:0032272","Term":"negative regulation of protein polymerization","Annotated":70,"Significant":5,"Expected":4.23,"Rank in p.value_classic":2535,"p.value_elim":0.41483,"p.value_classic":0.41698,"genes":"CDH5,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0007589","Term":"body fluid secretion","Annotated":70,"Significant":5,"Expected":4.23,"Rank in p.value_classic":2536,"p.value_elim":0.41483,"p.value_classic":0.41698,"genes":"AGR2,EDN1,NPR1,OAS2,TIFAB"} {"GO.ID":"GO:0043270","Term":"positive regulation of monoatomic ion transport","Annotated":155,"Significant":19,"Expected":9.36,"Rank in p.value_classic":568,"p.value_elim":0.41616,"p.value_classic":0.00253,"genes":"ABCB1,ANK2,ATP1B2,CCL5,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ2,LILRA2,P2RX4,P2RX7,SCN4B,SRI,TESC,TRDN"} {"GO.ID":"GO:0060249","Term":"anatomical structure homeostasis","Annotated":202,"Significant":18,"Expected":12.2,"Rank in p.value_classic":1197,"p.value_elim":0.41661,"p.value_classic":0.0633,"genes":"ADAM8,ANKH,ATP1B2,CD38,CDH5,COMP,CSF1,CXADR,IL7,NOD2,P2RX4,P2RX7,PDK4,PIWIL4,S1PR1,SNX10,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0001894","Term":"tissue homeostasis","Annotated":202,"Significant":18,"Expected":12.2,"Rank in p.value_classic":1198,"p.value_elim":0.41661,"p.value_classic":0.0633,"genes":"ADAM8,ANKH,ATP1B2,CD38,CDH5,COMP,CSF1,CXADR,IL7,NOD2,P2RX4,P2RX7,PDK4,PIWIL4,S1PR1,SNX10,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0019751","Term":"polyol metabolic process","Annotated":86,"Significant":6,"Expected":5.19,"Rank in p.value_classic":2537,"p.value_elim":0.41676,"p.value_classic":0.41914,"genes":"DGAT2,DHFR,GCH1,GK,NAAA,PLEK"} {"GO.ID":"GO:0090288","Term":"negative regulation of cellular response to growth factor stimulus","Annotated":86,"Significant":6,"Expected":5.19,"Rank in p.value_classic":2538,"p.value_elim":0.41676,"p.value_classic":0.41914,"genes":"AGT,CHRD,HTRA1,IL12A,MIR503,TNFAIP6"} {"GO.ID":"GO:0043535","Term":"regulation of blood vessel endothelial cell migration","Annotated":86,"Significant":6,"Expected":5.19,"Rank in p.value_classic":2539,"p.value_elim":0.41676,"p.value_classic":0.41914,"genes":"CD40,KLF4,MIR503,NRP1,P2RX4,VEGFC"} {"GO.ID":"GO:0032963","Term":"collagen metabolic process","Annotated":86,"Significant":6,"Expected":5.19,"Rank in p.value_classic":2540,"p.value_elim":0.41676,"p.value_classic":0.41914,"genes":"CIITA,CTSL,CTSS,MMP25,MMP9,P2RX7"} {"GO.ID":"GO:1903038","Term":"negative regulation of leukocyte cell-cell adhesion","Annotated":109,"Significant":25,"Expected":6.58,"Rank in p.value_classic":140,"p.value_elim":0.417,"p.value_classic":5.1e-09,"genes":"ASCL2,BCL6,BTN2A2,CD274,CD74,CD80,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,IRF1,JAK3,KLF4,LAG3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,ZC3H12A"} {"GO.ID":"GO:0043200","Term":"response to amino acid","Annotated":102,"Significant":7,"Expected":6.16,"Rank in p.value_classic":2541,"p.value_elim":0.41767,"p.value_classic":0.42026,"genes":"CASTOR1,EDN1,LYN,PNPLA3,SESN3,SOCS1,STAMBPL1"} {"GO.ID":"GO:0048002","Term":"antigen processing and presentation of peptide antigen","Annotated":63,"Significant":28,"Expected":3.8,"Rank in p.value_classic":30,"p.value_elim":0.41839,"p.value_classic":3.9e-18,"genes":"B2M,CD74,CTSL,CTSS,ERAP2,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,SLC11A1,TAP1,TAP2,TAPBP,TAPBPL"} {"GO.ID":"GO:0071219","Term":"cellular response to molecule of bacterial origin","Annotated":191,"Significant":34,"Expected":11.54,"Rank in p.value_classic":150,"p.value_elim":0.41903,"p.value_classic":1.1e-08,"genes":"ACOD1,CARD16,CASP7,CD274,CD40,CD80,CMPK2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,GBP2,GBP3,GBP5,JAK2,KLRK1,LILRA2,LITAF,LYN,MMP9,NOD2,PDCD1LG2,PDE4B,PLSCR4,PPM1E,RIPK2,SBNO2,SCIMP,STAP1,TICAM2,TIFAB,TLR10,ZC3H12A"} {"GO.ID":"GO:2001222","Term":"regulation of neuron migration","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2542,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"KIF26A,RAPGEF2,WDR62"} {"GO.ID":"GO:0001974","Term":"blood vessel remodeling","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2543,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"AGT,CEACAM1,EPAS1"} {"GO.ID":"GO:0045604","Term":"regulation of epidermal cell differentiation","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2544,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"DLL1,MAFF,PLAAT4"} {"GO.ID":"GO:0045910","Term":"negative regulation of DNA recombination","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2545,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"BCL6,PARP3,RMI2"} {"GO.ID":"GO:0090504","Term":"epiboly","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2546,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"CEACAM1,HBEGF,ITGB5"} {"GO.ID":"GO:0048489","Term":"synaptic vesicle transport","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2547,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"DNM1,DTNBP1,LRRK2"} {"GO.ID":"GO:0070988","Term":"demethylation","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2548,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0097178","Term":"ruffle assembly","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2549,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"ICAM1,SNX10,STAP1"} {"GO.ID":"GO:1904894","Term":"positive regulation of receptor signaling pathway via STAT","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2550,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"AGT,CCL5,JAK2"} {"GO.ID":"GO:0014911","Term":"positive regulation of smooth muscle cell migration","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2551,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"CCL5,NR4A3,NRP1"} {"GO.ID":"GO:0031641","Term":"regulation of myelination","Annotated":39,"Significant":3,"Expected":2.36,"Rank in p.value_classic":2552,"p.value_elim":0.41998,"p.value_classic":0.42161,"genes":"EGR2,TNFRSF21,TYMP"} {"GO.ID":"GO:0006915","Term":"apoptotic process","Annotated":1596,"Significant":125,"Expected":96.39,"Rank in p.value_classic":500,"p.value_elim":0.4201,"p.value_classic":0.00113,"genes":"ADAM8,AGT,AIFM2,ATF3,ATF5,ATP13A2,AURKB,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BUB1B,C3orf38,CAMK2D,CARD16,CASP4,CASP7,CCL5,CD274,CD28,CD38,CD40,CD74,CDCA7,CDH5,CDK1,CHAC1,COMP,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCR3,CYLD,DAB2,DEPTOR,DLL1,DRAM1,E2F1,E2F2,EBF4,EDN1,FAS,G0S2,GADD45B,GCH1,GHRL,GIMAP8,GRAMD4,HCAR2,HELLS,HGF,HLA-G,HTRA1,ICAM1,IDO1,IFI27,IFIT2,IFIT3,IGF2R,IL12A,IL31RA,IL7,IRF1,IRF7,JAK2,JAK3,KITLG,KLF4,KREMEN1,LAMP3,LRP5,LRRK2,LTA,LYN,MAD2L1,MCM2,MERTK,MMP9,MUC1,MYBL2,NLRP12,NOD2,NRP1,P2RX4,P2RX7,PCDHGC3,PDCD1,PDK4,PIM1,PLSCR1,PMAIP1,PML,POLB,PROK2,RALB,RAPGEF2,RIPK2,SCIN,SEPTIN4,SGPL1,STAT1,SYNE1,TGM2,TIFAB,TMEM109,TNFAIP8L3,TNFRSF21,TNFSF10,TNFSF18,TOP2A,TRIM69,TYRO3,UBD,UNG,USP53,XAF1,XKR6,XRCC2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0031401","Term":"positive regulation of protein modification process","Annotated":646,"Significant":57,"Expected":39.02,"Rank in p.value_classic":562,"p.value_elim":0.42015,"p.value_classic":0.00243,"genes":"AGT,AMER1,BANK1,C3,CCL5,CD40,CD74,CD80,CDH5,CLEC6A,CLSPN,CSF1,CX3CR1,DAB2,DTNBP1,EDN1,ENPP2,FAM107A,FAM20A,FAS,FAXDC2,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,LIMK2,LRRK2,LYN,MMD,MMP9,NCF1,NMI,NOD2,NRP1,OSM,P2RX7,PARP14,PARP9,PML,RALB,RAPGEF2,RIPK2,SEPTIN4,SLC11A1,TANK,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TRABD2A,VEGFC,ZC3H12A"} {"GO.ID":"GO:0031343","Term":"positive regulation of cell killing","Annotated":55,"Significant":19,"Expected":3.32,"Rank in p.value_classic":112,"p.value_elim":0.42202,"p.value_classic":2e-10,"genes":"B2M,CD1A,CD1C,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,KLRK1,LAG3,P2RX7,SLAMF6,STAP1,TAP2"} {"GO.ID":"GO:0062197","Term":"cellular response to chemical stress","Annotated":280,"Significant":18,"Expected":16.91,"Rank in p.value_classic":2557,"p.value_elim":0.42263,"p.value_classic":0.42692,"genes":"AIFM2,ATP13A2,CDK1,DHFR,EDN1,FAS,GCH1,HGF,IL18BP,KLF4,LRRK2,MMP9,NCF1,PXN,RELB,TIFAB,VRK2,ZC3H12A"} {"GO.ID":"GO:0002718","Term":"regulation of cytokine production involved in immune response","Annotated":105,"Significant":20,"Expected":6.34,"Rank in p.value_classic":266,"p.value_elim":0.42285,"p.value_classic":3.9e-06,"genes":"B2M,BCL6,CD74,HLA-A,HLA-E,HLA-F,HLA-G,JAK3,LITAF,NOD2,NR4A3,P2RX7,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:0043370","Term":"regulation of CD4-positive, alpha-beta T cell differentiation","Annotated":51,"Significant":14,"Expected":3.08,"Rank in p.value_classic":231,"p.value_elim":0.42403,"p.value_classic":1.2e-06,"genes":"ASCL2,BCL6,CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,RIPK2,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:0048468","Term":"cell development","Annotated":2205,"Significant":164,"Expected":133.17,"Rank in p.value_classic":542,"p.value_elim":0.42461,"p.value_classic":0.00183,"genes":"ADAM8,ADGB,ALAS1,ANK2,ANLN,APPL2,ASB2,ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BATF2,BATF3,BCL6,BHLHE41,BTN2A2,C21orf91,C3,CD101,CD28,CD38,CD74,CD80,CD83,CDH5,CDK1,CEACAM1,COMP,CSF1,CTLA4,CTSL,CX3CR1,CXADR,CYLD,CYSLTR1,DAB1,DAB2,DAZL,DHFR,DLL1,DMC1,DTNBP1,DYNLT1,EDN1,EGR2,EPAS1,EPHB3,ESCO2,FAXDC2,FGL2,FLT3LG,FSTL4,GHRL,GLDN,GPR183,GRIN3A,HAPLN3,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-G,HORMAD1,ICAM1,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KREMEN1,LAG3,LILRB3,LRP5,LRRK2,LTA,LYN,MAF,MARVELD2,MERTK,MMP9,MYOZ2,NCAPG2,NPM2,NRCAM,NRN1,NRP1,NYAP2,OCA2,OLIG1,ONECUT2,OSM,PAQR5,PAQR8,PCDH12,PIM1,PLEK,PLXNA2,PML,PRKX,PTGER4,RAPGEF2,RASGRF1,RELB,RIPK2,RSAD2,RTN4RL1,S100A10,SBNO2,SCARF1,SCIN,SDC2,SEMA6B,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC4A7,SNX10,SOCS1,SPTBN4,SSBP3,STAT1,STMN1,SYNE1,SYT1,TAL1,TBX21,TESC,TGM2,TIFAB,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF13B,TNFSF8,TOP2A,TYMS,TYRO3,UBD,VCAM1,VCAN,VEGFC,WDR62,WEE1,XRCC2,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0070232","Term":"regulation of T cell apoptotic process","Annotated":36,"Significant":9,"Expected":2.17,"Rank in p.value_classic":393,"p.value_elim":0.42463,"p.value_classic":0.00022,"genes":"ADAM8,BCL2L11,CCL5,CD274,GIMAP8,IDO1,JAK3,P2RX7,PDCD1"} {"GO.ID":"GO:1901654","Term":"response to ketone","Annotated":167,"Significant":11,"Expected":10.09,"Rank in p.value_classic":2558,"p.value_elim":0.42473,"p.value_classic":0.42804,"genes":"ACOD1,CD38,EDN1,GNG2,JAK2,KLF4,NCF1,PTGER4,SLC12A3,TYMS,XRN1"} {"GO.ID":"GO:0072331","Term":"signal transduction by p53 class mediator","Annotated":167,"Significant":11,"Expected":10.09,"Rank in p.value_classic":2559,"p.value_elim":0.42473,"p.value_classic":0.42804,"genes":"AURKB,CD74,E2F1,E2F2,GTSE1,MUC1,PMAIP1,PML,PYHIN1,TIFAB,TMEM109"} {"GO.ID":"GO:1900024","Term":"regulation of substrate adhesion-dependent cell spreading","Annotated":55,"Significant":4,"Expected":3.32,"Rank in p.value_classic":2554,"p.value_elim":0.42485,"p.value_classic":0.42677,"genes":"DAB2,GBP1,NRP1,S100A10"} {"GO.ID":"GO:0031098","Term":"stress-activated protein kinase signaling cascade","Annotated":55,"Significant":4,"Expected":3.32,"Rank in p.value_classic":2555,"p.value_elim":0.42485,"p.value_classic":0.42677,"genes":"FAS,LYN,NOD2,SCIMP"} {"GO.ID":"GO:0060998","Term":"regulation of dendritic spine development","Annotated":55,"Significant":4,"Expected":3.32,"Rank in p.value_classic":2556,"p.value_elim":0.42485,"p.value_classic":0.42677,"genes":"C21orf91,DTNBP1,FSTL4,GRIN3A"} {"GO.ID":"GO:0071396","Term":"cellular response to lipid","Annotated":493,"Significant":56,"Expected":29.77,"Rank in p.value_classic":260,"p.value_elim":0.42492,"p.value_classic":3.4e-06,"genes":"ACOD1,BCL2L11,BRCA1,CARD16,CASP7,CCNA2,CD274,CD40,CD80,CMPK2,CRHBP,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,DAB2,DGAT2,EDN1,FAM107A,GBP2,GBP3,GBP5,GNG2,GRAMD1B,JAK2,KLF4,KLRK1,LBH,LILRA2,LITAF,LPL,LYN,MMP9,NCF1,NOD2,NR4A3,PADI2,PAQR8,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PLSCR4,PPM1E,PTGER4,RIPK2,SBNO2,SCIMP,SSTR2,STAP1,TESC,TICAM2,TIFAB,ZC3H12A"} {"GO.ID":"GO:0045332","Term":"phospholipid translocation","Annotated":42,"Significant":7,"Expected":2.54,"Rank in p.value_classic":785,"p.value_elim":0.42616,"p.value_classic":0.01208,"genes":"ABCB1,ANO4,ATP8B1,P2RX7,PLSCR1,PLSCR4,XKR6"} {"GO.ID":"GO:0006941","Term":"striated muscle contraction","Annotated":135,"Significant":9,"Expected":8.15,"Rank in p.value_classic":2562,"p.value_elim":0.42657,"p.value_classic":0.42955,"genes":"ANK2,CAMK2D,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SRI,ZC3H12A"} {"GO.ID":"GO:0051298","Term":"centrosome duplication","Annotated":71,"Significant":5,"Expected":4.29,"Rank in p.value_classic":2560,"p.value_elim":0.42691,"p.value_classic":0.42908,"genes":"BRCA1,CCNF,CHMP4C,NDC80,WDR62"} {"GO.ID":"GO:0021510","Term":"spinal cord development","Annotated":71,"Significant":5,"Expected":4.29,"Rank in p.value_classic":2561,"p.value_elim":0.42691,"p.value_classic":0.42908,"genes":"CHRD,DLL1,IFT122,MDGA1,TAL1"} {"GO.ID":"GO:0031398","Term":"positive regulation of protein ubiquitination","Annotated":103,"Significant":7,"Expected":6.22,"Rank in p.value_classic":2588,"p.value_elim":0.42767,"p.value_classic":0.43028,"genes":"AMER1,FAM107A,LRRK2,NMI,NOD2,RIPK2,SEPTIN4"} {"GO.ID":"GO:0090322","Term":"regulation of superoxide metabolic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2563,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DHFR,GCH1"} {"GO.ID":"GO:0045672","Term":"positive regulation of osteoclast differentiation","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2564,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"CSF1,TNFRSF11A"} {"GO.ID":"GO:0070328","Term":"triglyceride homeostasis","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2565,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DGAT2,LPL"} {"GO.ID":"GO:0022038","Term":"corpus callosum development","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2566,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"EPHB3,RTN4RL1"} {"GO.ID":"GO:0034390","Term":"smooth muscle cell apoptotic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2567,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"EDN1,IL12A"} {"GO.ID":"GO:0060155","Term":"platelet dense granule organization","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2568,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DTNBP1,F2RL3"} {"GO.ID":"GO:0060142","Term":"regulation of syncytium formation by plasma membrane fusion","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2569,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"CXCL10,CXCL9"} {"GO.ID":"GO:0002021","Term":"response to dietary excess","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2570,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"APPL2,SLC12A3"} {"GO.ID":"GO:2000050","Term":"regulation of non-canonical Wnt signaling pathway","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2571,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DAB2,RNF213"} {"GO.ID":"GO:1900371","Term":"regulation of purine nucleotide biosynthetic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2572,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"PDK4,PID1"} {"GO.ID":"GO:0030808","Term":"regulation of nucleotide biosynthetic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2573,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"PDK4,PID1"} {"GO.ID":"GO:0050892","Term":"intestinal absorption","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2574,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"GCNT3,SLC2A5"} {"GO.ID":"GO:0048384","Term":"retinoic acid receptor signaling pathway","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2575,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DHRS3,PML"} {"GO.ID":"GO:0055090","Term":"acylglycerol homeostasis","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2576,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DGAT2,LPL"} {"GO.ID":"GO:0021772","Term":"olfactory bulb development","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2577,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"ATF5,LRRK2"} {"GO.ID":"GO:0006312","Term":"mitotic recombination","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2578,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DMC1,RAD54B"} {"GO.ID":"GO:0035313","Term":"wound healing, spreading of epidermal cells","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2579,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"HBEGF,ITGB5"} {"GO.ID":"GO:0050926","Term":"regulation of positive chemotaxis","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2580,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"S1PR1,VEGFC"} {"GO.ID":"GO:0048799","Term":"animal organ maturation","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2581,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"SNX10,XYLT1"} {"GO.ID":"GO:0008210","Term":"estrogen metabolic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2582,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"CYP1A1,SGPL1"} {"GO.ID":"GO:0046164","Term":"alcohol catabolic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2583,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"GK,SCARF1"} {"GO.ID":"GO:0051894","Term":"positive regulation of focal adhesion assembly","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2584,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"NRP1,S100A10"} {"GO.ID":"GO:0010039","Term":"response to iron ion","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2585,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"B2M,CYP1A1"} {"GO.ID":"GO:1903580","Term":"positive regulation of ATP metabolic process","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2586,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"P2RX7,PID1"} {"GO.ID":"GO:0035883","Term":"enteroendocrine cell differentiation","Annotated":24,"Significant":2,"Expected":1.45,"Rank in p.value_classic":2587,"p.value_elim":0.42871,"p.value_classic":0.43,"genes":"DLL1,SIDT2"} {"GO.ID":"GO:0007599","Term":"hemostasis","Annotated":178,"Significant":17,"Expected":10.75,"Rank in p.value_classic":1069,"p.value_elim":0.42873,"p.value_classic":0.04095,"genes":"CD40,CEACAM1,COMP,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,JAK2,LYN,MERTK,PLEK,PLSCR1,SERPING1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0099537","Term":"trans-synaptic signaling","Annotated":547,"Significant":38,"Expected":33.04,"Rank in p.value_classic":1872,"p.value_elim":0.43159,"p.value_classic":0.20415,"genes":"ADORA3,AKAP7,ASIC1,CADPS2,CD38,COLQ,CRHBP,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GABRA3,GHRL,GRIN3A,GRM8,HRH2,INA,INSYN2A,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,P2RX4,P2RX7,PRRT2,RAPGEF2,RASGRF1,STX11,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:2000401","Term":"regulation of lymphocyte migration","Annotated":60,"Significant":8,"Expected":3.62,"Rank in p.value_classic":957,"p.value_elim":0.43313,"p.value_classic":0.02704,"genes":"ADAM8,ASCL2,CCL5,CCL7,CXCL10,KLRK1,PADI2,TNFRSF14"} {"GO.ID":"GO:0019216","Term":"regulation of lipid metabolic process","Annotated":233,"Significant":15,"Expected":14.07,"Rank in p.value_classic":2592,"p.value_elim":0.4335,"p.value_classic":0.43743,"genes":"APPL2,BRCA1,C3,CD74,CEACAM1,DAB2,GOLM1,HCAR2,LACTB,NR4A3,PDE3B,PDK4,RNF213,SLC45A3,TTC39B"} {"GO.ID":"GO:0006936","Term":"muscle contraction","Annotated":247,"Significant":19,"Expected":14.92,"Rank in p.value_classic":1728,"p.value_elim":0.4338,"p.value_classic":0.16594,"genes":"ANK2,CAMK2D,CD38,COMP,EDN1,GHRL,KCNE5,KCNJ2,MYOF,P2RX4,PDE4B,PROK2,SCN4B,SRI,SSPN,SSTR2,TIFAB,TRDN,ZC3H12A"} {"GO.ID":"GO:0000723","Term":"telomere maintenance","Annotated":152,"Significant":10,"Expected":9.18,"Rank in p.value_classic":2590,"p.value_elim":0.43394,"p.value_classic":0.43711,"genes":"AURKB,CCNE2,EXO1,FEN1,GCH1,PARP3,PKIB,PML,RECQL4,XRN1"} {"GO.ID":"GO:0032370","Term":"positive regulation of lipid transport","Annotated":67,"Significant":8,"Expected":4.05,"Rank in p.value_classic":1106,"p.value_elim":0.43529,"p.value_classic":0.04789,"genes":"ACSL1,DAB2,EDN1,EEPD1,GHRL,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0002066","Term":"columnar/cuboidal epithelial cell development","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2593,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"DLL1,SIDT2,TYMS"} {"GO.ID":"GO:0070266","Term":"necroptotic process","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2594,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"CYLD,FAS,ZBP1"} {"GO.ID":"GO:0043300","Term":"regulation of leukocyte degranulation","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2595,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"CEACAM1,HLA-F,LYN"} {"GO.ID":"GO:0002279","Term":"mast cell activation involved in immune response","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2596,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"LYN,NR4A3,S100A13"} {"GO.ID":"GO:0021762","Term":"substantia nigra development","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2597,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"INA,PADI2,SYNGR3"} {"GO.ID":"GO:1903409","Term":"reactive oxygen species biosynthetic process","Annotated":40,"Significant":3,"Expected":2.42,"Rank in p.value_classic":2598,"p.value_elim":0.43627,"p.value_classic":0.43792,"genes":"CTNS,CYP1A1,NCF1"} {"GO.ID":"GO:0071333","Term":"cellular response to glucose stimulus","Annotated":104,"Significant":7,"Expected":6.28,"Rank in p.value_classic":2599,"p.value_elim":0.43764,"p.value_classic":0.44027,"genes":"GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,SIDT2,SRI"} {"GO.ID":"GO:0032502","Term":"developmental process","Annotated":4867,"Significant":329,"Expected":293.94,"Rank in p.value_classic":649,"p.value_elim":0.4383,"p.value_classic":0.00455,"genes":"AATK,ACOD1,ADAM8,ADAMTS15,ADGB,AGR2,AGT,AIM2,ALAS1,AMER1,AMOT,ANK2,ANKH,ANLN,ANTXR1,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP1B2,ATP8B1,AURKB,B2M,BATF2,BATF3,BCL2L11,BCL6,BHLHE41,BRCA1,BTN2A2,C1QTNF5,C21orf91,C3,C3orf70,CASP7,CASZ1,CCL13,CCL7,CCNA2,CCNF,CD101,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CDKN2C,CDS1,CEACAM1,CELSR1,CENPF,CENPU,CHAC1,CHMP4C,CHRD,CIBAR1,COL9A2,COLQ,COMP,CSF1,CTLA4,CTNS,CTSL,CX3CR1,CXADR,CXCL10,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DNAAF1,DTNBP1,DYNLT1,E2F1,E2F2,E2F8,EDA,EDN1,EGR2,ENPP2,EPAS1,EPHB3,EPOP,ESCO2,ETV7,EXO1,FAM20A,FAXDC2,FGD5,FGL1,FGL2,FLT3LG,FMNL2,FSTL4,G6PC1,GABRA3,GADD45B,GCNT3,GFRA2,GHRL,GINS1,GLDN,GLIPR2,GLUL,GPR183,GRIN3A,GSTK1,HAPLN3,HBEGF,HELLS,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-E,HLA-G,HORMAD1,HSD11B1,HTRA1,ICAM1,IDO1,IFITM1,IFT122,IGF2R,IL12A,IL12RB1,IL15,IL15RA,IL1RN,IL27,IL31RA,IL4I1,IL7,INA,IQGAP3,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMB3,LBH,LGI2,LILRB3,LIMK2,LPL,LRATD1,LRP5,LRRK2,LTA,LYN,LYVE1,MAF,MAFF,MARCKSL1,MARVELD2,MCM2,MDGA1,MERTK,MICAL2,MIR503,MMD,MMP25,MMP9,MPZL2,MTSS1,MYO7B,MYOZ2,NCAPG2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRN1,NRP1,NYAP2,OAS2,OCA2,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PADI2,PAQR5,PAQR8,PARP3,PCDH12,PCDHGC3,PDCD1,PDE3B,PID1,PIM1,PIWIL4,PKD1L3,PLAAT3,PLAAT4,PLCD3,PLEK,PLPP4,PLXNA2,PML,PNPLA3,POLB,PRKX,PROK2,PSMB10,PSMB8,PTGER4,PTPRU,RAPGEF2,RASGRF1,RELB,RHOBTB3,RIPK2,RNF213,RRM2,RSAD2,RTN4RL1,RXFP1,S100A10,S1PR1,SAT1,SBNO2,SCARF1,SCIN,SCO2,SDC2,SECTM1,SELENOP,SEMA6B,SEPTIN4,SERINC5,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC20A1,SLC45A3,SLC4A7,SNX10,SOAT1,SOBP,SOCS1,SOX17,SPATA9,SPTBN4,SRI,SSBP3,SSTR2,STAP1,STAT1,STAT2,STEAP4,STMN1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TBATA,TBX21,TDRD9,TESC,TGM2,THBS2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TNFSF8,TOP2A,TRABD2A,TYMP,TYMS,TYRO3,UBD,UNG,VAMP5,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,WWP1,XKR6,XRCC2,XYLT1,ZC3H12A,ZMYND15"} {"GO.ID":"GO:0018108","Term":"peptidyl-tyrosine phosphorylation","Annotated":217,"Significant":31,"Expected":13.11,"Rank in p.value_classic":274,"p.value_elim":0.4385,"p.value_classic":6.6e-06,"genes":"AATK,AGT,BANK1,CCL5,CD40,CD74,CD80,CLEC6A,ENPP2,HBEGF,HGF,IL12A,IL15,IL22RA2,IL31RA,IL7,JAK2,JAK3,KITLG,LYN,MVP,NCF1,NOD2,NRP1,OSM,PARP14,PARP9,RIPK2,SOCS1,TNFRSF14,TNFSF18"} {"GO.ID":"GO:0001885","Term":"endothelial cell development","Annotated":56,"Significant":4,"Expected":3.38,"Rank in p.value_classic":2600,"p.value_elim":0.43853,"p.value_classic":0.44047,"genes":"CDH5,ICAM1,MARVELD2,RAPGEF2"} {"GO.ID":"GO:0007585","Term":"respiratory gaseous exchange by respiratory system","Annotated":56,"Significant":4,"Expected":3.38,"Rank in p.value_classic":2601,"p.value_elim":0.43853,"p.value_classic":0.44047,"genes":"CSF2RB,CYSLTR1,ECEL1,EDN1"} {"GO.ID":"GO:0009888","Term":"tissue development","Annotated":1515,"Significant":93,"Expected":91.5,"Rank in p.value_classic":2609,"p.value_elim":0.43875,"p.value_classic":0.44927,"genes":"ADAM8,AGR2,AGT,AMER1,ANKH,ASB2,ASCL2,ATF3,C3,CDH5,CDK1,CEACAM1,CELSR1,CENPF,CHRD,COMP,CSF1,CTNS,CXADR,CXCL10,CYP1A1,DAB2,DGAT2,DHRS9,DLL1,DNAAF1,E2F8,EDA,EDN1,EGR2,EPAS1,FAM20A,GCNT3,GHRL,GLIPR2,GSTK1,HBEGF,HESX1,HGF,HLA-DRB1,ICAM1,IFT122,IL31RA,IQGAP3,ITGA7,ITGB5,JAK2,KITLG,KLF4,LAMB3,LBH,LPL,LRP5,MAF,MAFF,MARVELD2,MICAL2,MMP9,MTSS1,MYOZ2,NRP1,ONECUT2,OVOL1,P2RX7,PIM1,PLAAT3,PLAAT4,PLXNA2,PML,PRKX,RAPGEF2,RXFP1,S1PR1,SBNO2,SCIN,SECTM1,SEMA6B,SIDT2,SLC20A1,SLC4A7,SNX10,SOX17,SSBP3,STAT1,STMN1,SYNE1,TAL1,TGM2,TMEM119,TYMS,VAMP5,VEGFC,XRCC2"} {"GO.ID":"GO:0045638","Term":"negative regulation of myeloid cell differentiation","Annotated":72,"Significant":5,"Expected":4.35,"Rank in p.value_classic":2602,"p.value_elim":0.43894,"p.value_classic":0.44114,"genes":"CEACAM1,DLL1,LILRB3,LYN,TNFAIP6"} {"GO.ID":"GO:0033273","Term":"response to vitamin","Annotated":72,"Significant":5,"Expected":4.35,"Rank in p.value_classic":2603,"p.value_elim":0.43894,"p.value_classic":0.44114,"genes":"CD40,CXCL10,CYP1A1,PIM1,TYMS"} {"GO.ID":"GO:0036465","Term":"synaptic vesicle recycling","Annotated":72,"Significant":5,"Expected":4.35,"Rank in p.value_classic":2604,"p.value_elim":0.43894,"p.value_classic":0.44114,"genes":"DNM1,ITSN1,LRRK2,STX1A,SYT1"} {"GO.ID":"GO:0006805","Term":"xenobiotic metabolic process","Annotated":72,"Significant":5,"Expected":4.35,"Rank in p.value_classic":2605,"p.value_elim":0.43894,"p.value_classic":0.44114,"genes":"ABCB1,ACSL1,CBR3,CYP1A1,EPHX1"} {"GO.ID":"GO:0046620","Term":"regulation of organ growth","Annotated":72,"Significant":5,"Expected":4.35,"Rank in p.value_classic":2606,"p.value_elim":0.43894,"p.value_classic":0.44114,"genes":"BCL2L11,CDK1,EDN1,IL7,PIM1"} {"GO.ID":"GO:0050673","Term":"epithelial cell proliferation","Annotated":348,"Significant":22,"Expected":21.02,"Rank in p.value_classic":2607,"p.value_elim":0.43899,"p.value_classic":0.44381,"genes":"B2M,CCL5,CEACAM1,DAB2,FGL1,GHRL,HGF,IL12A,IQGAP3,MIR503,MTSS1,NOD2,NR4A3,NRP1,OVOL1,PRKX,PROK2,RASGRF1,SIDT2,STAT1,UHRF1,VEGFC"} {"GO.ID":"GO:0001558","Term":"regulation of cell growth","Annotated":348,"Significant":22,"Expected":21.02,"Rank in p.value_classic":2608,"p.value_elim":0.43899,"p.value_classic":0.44381,"genes":"AGT,BCL6,BRCA1,CAMK2D,CD38,CDKN2C,CEACAM1,CISH,DAB2,EDN1,FAM107A,FSTL4,HBEGF,JADE2,KIF26A,NPR1,NRCAM,NRP1,PML,SEMA6B,SOX17,SYT1"} {"GO.ID":"GO:0006302","Term":"double-strand break repair","Annotated":296,"Significant":25,"Expected":17.88,"Rank in p.value_classic":1154,"p.value_elim":0.43901,"p.value_classic":0.05627,"genes":"BRCA1,CDC45,CDCA5,DMC1,DTX3L,EME1,ESCO2,FEN1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,PARP3,PARP9,PML,POLB,RAD54B,RAD54L,RECQL4,RMI2,TONSL,UHRF1,XRCC2"} {"GO.ID":"GO:0060627","Term":"regulation of vesicle-mediated transport","Annotated":443,"Significant":38,"Expected":26.76,"Rank in p.value_classic":848,"p.value_elim":0.43962,"p.value_classic":0.01818,"genes":"APPL2,ATP13A2,B2M,C2,C3,C4A,C4B,CADPS2,CD300LF,CEACAM1,DAB2,DLL1,DTNBP1,DYSF,ERC2,FCN1,HLA-F,IL15,IL15RA,LRRK2,LYN,MERTK,NECAB2,NOD2,NRP1,PLSCR1,PRRT2,S100A10,SEPTIN4,SLAMF1,SLC11A1,STAP1,STX1A,SV2B,SYNE1,SYT1,SYT6,TGM2"} {"GO.ID":"GO:0080134","Term":"regulation of response to stress","Annotated":1178,"Significant":127,"Expected":71.15,"Rank in p.value_classic":95,"p.value_elim":0.44022,"p.value_classic":3.5e-11,"genes":"ABCB1,ACOD1,ADAM8,AGR2,AGT,AIFM2,AIM2,APOBEC3G,APPL2,AURKB,BCL2L11,BCL6,BRCA1,C3,CARD16,CASP4,CCL5,CD274,CD28,CD300LF,CD74,CDH5,CEACAM1,CFH,CLEC6A,COLEC12,CRHBP,CTSS,CYLD,DDX60,DHFR,DTX3L,EDN1,ENPP4,FAS,FCN1,FGL2,GBP2,GBP5,GCH1,GHRL,GPR31,GRAMD4,GSDMD,HBEGF,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL22RA2,IL27,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,KLRK1,KREMEN1,LAG3,LILRA2,LPL,LRRK2,LTA,LYN,MEFV,MMP9,MUC1,NCF1,NLRC5,NLRP12,NMI,NOD2,OAS3,OPTN,OSM,PARP14,PARP3,PARP9,PLSCR1,PMAIP1,PML,PTGER4,PYHIN1,RIPK2,RMI2,RSAD2,RTN4RL1,SBNO2,SCARF1,SCIMP,SERPING1,SESN3,SLAMF6,SLAMF8,STAP1,STAT1,STAT2,SUCNR1,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFRSF11A,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,WDR76,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0015748","Term":"organophosphate ester transport","Annotated":123,"Significant":12,"Expected":7.43,"Rank in p.value_classic":1219,"p.value_elim":0.4424,"p.value_classic":0.06794,"genes":"ABCB1,ABCC11,ANKH,ANO4,ATP8B1,G6PC1,P2RX7,PLSCR1,PLSCR4,SLC37A1,TNFAIP8L3,XKR6"} {"GO.ID":"GO:0002440","Term":"production of molecular mediator of immune response","Annotated":186,"Significant":25,"Expected":11.23,"Rank in p.value_classic":372,"p.value_elim":0.4437,"p.value_classic":0.00014,"genes":"B2M,BCL6,CD28,CD74,EXO1,HLA-A,HLA-E,HLA-F,HLA-G,JAK3,LITAF,NOD2,NR4A3,P2RX7,PARP3,POLB,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14,UNG"} {"GO.ID":"GO:0042063","Term":"gliogenesis","Annotated":289,"Significant":23,"Expected":17.45,"Rank in p.value_classic":1427,"p.value_elim":0.44497,"p.value_classic":0.10681,"genes":"ASCL2,ATP1B2,CDK1,CDKN2C,CSF1,CX3CR1,CYSLTR1,DAB1,DLL1,EGR2,GPR183,HAPLN3,KCNJ10,LTA,LYN,OLIG1,P2RX4,SLC45A3,STAP1,TAL1,TNFRSF21,VCAN,VEGFC"} {"GO.ID":"GO:0032970","Term":"regulation of actin filament-based process","Annotated":333,"Significant":21,"Expected":20.11,"Rank in p.value_classic":2631,"p.value_elim":0.44645,"p.value_classic":0.45117,"genes":"ANK2,CAMK2D,CELSR1,EDN1,FAM107A,FSCN1,KCNJ2,MTSS1,NRP1,PDE4B,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,SRI,STMN1,TMSB10"} {"GO.ID":"GO:1901796","Term":"regulation of signal transduction by p53 class mediator","Annotated":105,"Significant":7,"Expected":6.34,"Rank in p.value_classic":2610,"p.value_elim":0.44759,"p.value_classic":0.45024,"genes":"AURKB,CD74,MUC1,PMAIP1,PML,PYHIN1,TIFAB"} {"GO.ID":"GO:1902531","Term":"regulation of intracellular signal transduction","Annotated":1534,"Significant":116,"Expected":92.65,"Rank in p.value_classic":665,"p.value_elim":0.44933,"p.value_classic":0.00554,"genes":"ADAM8,AGT,AIM2,AKAP7,AMOT,APOL3,ATF3,AURKB,BANK1,BCL2L11,BCL6,BIRC5,BRCA1,BTN2A2,CARD16,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD40,CD74,CEACAM1,CLEC6A,CSF1,CTNS,CX3CR1,CYLD,DAB2,DEPTOR,EDA,EDN1,F2RL3,FAM13A,FAS,FGD5,GADD45B,GAREM1,GBP1,GBP7,GHRL,GLIPR2,GPR183,HBEGF,HELLS,HGF,HLA-DRB1,HLA-G,ICAM1,IFI35,IFIT5,IQGAP3,ITSN1,JAK2,KITLG,LBH,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MIR503,MMP9,MUC1,MYOZ2,NCF1,NDC80,NECAB2,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OPTN,OSM,P2RX4,P2RX7,PDE3B,PIM1,PLEK,PMAIP1,PML,PYHIN1,RAPGEF2,RASGRF1,RIPK2,S100A13,SCIMP,SECTM1,SEPTIN4,SESN3,SLAMF1,SLC20A1,STAMBPL1,STAT1,STMN1,TAGAP,TANK,TGM2,TICAM2,TIFA,TIFAB,TLR7,TNFAIP8L3,TNFRSF11A,TNFSF10,TRIM22,UBD,VRK2,WDR76,ZC3H12A,ZWINT"} {"GO.ID":"GO:0048259","Term":"regulation of receptor-mediated endocytosis","Annotated":89,"Significant":6,"Expected":5.38,"Rank in p.value_classic":2632,"p.value_elim":0.44933,"p.value_classic":0.45177,"genes":"B2M,C3,DAB2,DTNBP1,NECAB2,SYNE1"} {"GO.ID":"GO:0001975","Term":"response to amphetamine","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2611,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ASIC1,EDN1"} {"GO.ID":"GO:0006656","Term":"phosphatidylcholine biosynthetic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2612,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"CDS1,PCYT1A"} {"GO.ID":"GO:1901659","Term":"glycosyl compound biosynthetic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2613,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"PRTFDC1,TK1"} {"GO.ID":"GO:0039529","Term":"RIG-I signaling pathway","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2614,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"DDX60,OAS3"} {"GO.ID":"GO:0051043","Term":"regulation of membrane protein ectodomain proteolysis","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2615,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ADAM8,TSPAN15"} {"GO.ID":"GO:2000352","Term":"negative regulation of endothelial cell apoptotic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2616,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"CDH5,ICAM1"} {"GO.ID":"GO:0042417","Term":"dopamine metabolic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2617,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"GCH1,NPR1"} {"GO.ID":"GO:1904353","Term":"regulation of telomere capping","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2618,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"AURKB,PKIB"} {"GO.ID":"GO:0051349","Term":"positive regulation of lyase activity","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2619,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0051491","Term":"positive regulation of filopodium assembly","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2620,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"FSCN1,NRP1"} {"GO.ID":"GO:0051497","Term":"negative regulation of stress fiber assembly","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2621,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"S1PR1,STMN1"} {"GO.ID":"GO:0031281","Term":"positive regulation of cyclase activity","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2622,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0046471","Term":"phosphatidylglycerol metabolic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2623,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"LCLAT1,PLB1"} {"GO.ID":"GO:0046475","Term":"glycerophospholipid catabolic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2624,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ENPP2,PLB1"} {"GO.ID":"GO:0033688","Term":"regulation of osteoblast proliferation","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2625,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"LRP5,TMEM119"} {"GO.ID":"GO:0021532","Term":"neural tube patterning","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2626,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"SOX17,SSBP3"} {"GO.ID":"GO:0048843","Term":"negative regulation of axon extension involved in axon guidance","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2627,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"NRP1,SEMA6B"} {"GO.ID":"GO:0000038","Term":"very long-chain fatty acid metabolic process","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2628,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ACOT4,ACSL1"} {"GO.ID":"GO:1902547","Term":"regulation of cellular response to vascular endothelial growth factor stimulus","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2629,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"DLL1,IL12A"} {"GO.ID":"GO:0021988","Term":"olfactory lobe development","Annotated":25,"Significant":2,"Expected":1.51,"Rank in p.value_classic":2630,"p.value_elim":0.44959,"p.value_classic":0.45091,"genes":"ATF5,LRRK2"} {"GO.ID":"GO:0007254","Term":"JNK cascade","Annotated":154,"Significant":10,"Expected":9.3,"Rank in p.value_classic":2635,"p.value_elim":0.45037,"p.value_classic":0.45357,"genes":"CYLD,GADD45B,LRRK2,NCF1,NOD2,NRK,PTGER4,RIPK2,SLAMF1,TLR7"} {"GO.ID":"GO:1903037","Term":"regulation of leukocyte cell-cell adhesion","Annotated":311,"Significant":57,"Expected":18.78,"Rank in p.value_classic":60,"p.value_elim":0.4505,"p.value_classic":2.8e-14,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CTLA4,CYLD,FGL1,FGL2,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL4I1,IL7,IRF1,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LYN,NOD2,NR4A3,PDCD1LG2,RIPK2,SLAMF1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:0090277","Term":"positive regulation of peptide hormone secretion","Annotated":73,"Significant":5,"Expected":4.41,"Rank in p.value_classic":2633,"p.value_elim":0.45091,"p.value_classic":0.45313,"genes":"CD38,GHRL,HLA-DRB1,JAK2,SRI"} {"GO.ID":"GO:0001892","Term":"embryonic placenta development","Annotated":73,"Significant":5,"Expected":4.41,"Rank in p.value_classic":2634,"p.value_elim":0.45091,"p.value_classic":0.45313,"genes":"ASCL2,E2F8,EPAS1,PCDH12,PLCD3"} {"GO.ID":"GO:0098542","Term":"defense response to other organism","Annotated":895,"Significant":149,"Expected":54.05,"Rank in p.value_classic":9,"p.value_elim":0.4512,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,BATF2,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD74,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CSF1,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,DDX60,DTX3L,EDN1,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GRAMD4,GSDMA,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-E,HLA-F,HLA-G,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL27,IL31RA,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LTA,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,P2RX7,PARP14,PARP9,PLSCR1,PMAIP1,PML,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAT1,STAT2,TANK,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF14,TNFSF8,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0050670","Term":"regulation of lymphocyte proliferation","Annotated":193,"Significant":38,"Expected":11.66,"Rank in p.value_classic":103,"p.value_elim":0.45128,"p.value_classic":7e-11,"genes":"BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CTLA4,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,PDCD1LG2,RIPK2,SLAMF1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0045670","Term":"regulation of osteoclast differentiation","Annotated":57,"Significant":4,"Expected":3.44,"Rank in p.value_classic":2640,"p.value_elim":0.45212,"p.value_classic":0.45409,"genes":"CSF1,LILRB3,TNFAIP6,TNFRSF11A"} {"GO.ID":"GO:0035914","Term":"skeletal muscle cell differentiation","Annotated":57,"Significant":4,"Expected":3.44,"Rank in p.value_classic":2641,"p.value_elim":0.45212,"p.value_classic":0.45409,"genes":"ASB2,ATF3,EGR2,MAFF"} {"GO.ID":"GO:2000379","Term":"positive regulation of reactive oxygen species metabolic process","Annotated":57,"Significant":4,"Expected":3.44,"Rank in p.value_classic":2642,"p.value_elim":0.45212,"p.value_classic":0.45409,"genes":"ACOD1,AGT,PID1,ZC3H12A"} {"GO.ID":"GO:0006940","Term":"regulation of smooth muscle contraction","Annotated":41,"Significant":3,"Expected":2.48,"Rank in p.value_classic":2636,"p.value_elim":0.45238,"p.value_classic":0.45405,"genes":"EDN1,GHRL,PROK2"} {"GO.ID":"GO:0033344","Term":"cholesterol efflux","Annotated":41,"Significant":3,"Expected":2.48,"Rank in p.value_classic":2637,"p.value_elim":0.45238,"p.value_classic":0.45405,"genes":"EEPD1,SOAT1,TTC39B"} {"GO.ID":"GO:0002448","Term":"mast cell mediated immunity","Annotated":41,"Significant":3,"Expected":2.48,"Rank in p.value_classic":2638,"p.value_elim":0.45238,"p.value_classic":0.45405,"genes":"LYN,NR4A3,S100A13"} {"GO.ID":"GO:0050907","Term":"detection of chemical stimulus involved in sensory perception","Annotated":41,"Significant":3,"Expected":2.48,"Rank in p.value_classic":2639,"p.value_elim":0.45238,"p.value_classic":0.45405,"genes":"OR2I1P,PKD1L3,RTP4"} {"GO.ID":"GO:0031214","Term":"biomineral tissue development","Annotated":138,"Significant":9,"Expected":8.33,"Rank in p.value_classic":2643,"p.value_elim":0.45265,"p.value_classic":0.45568,"genes":"ANKH,COMP,FAM20A,P2RX7,S1PR1,SBNO2,SLC20A1,SNX10,TMEM119"} {"GO.ID":"GO:0042593","Term":"glucose homeostasis","Annotated":187,"Significant":12,"Expected":11.29,"Rank in p.value_classic":2644,"p.value_elim":0.45352,"p.value_classic":0.45705,"genes":"APPL2,G6PC1,GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,PDK4,SESN3,SIDT2,SRI,SUCNR1"} {"GO.ID":"GO:0033044","Term":"regulation of chromosome organization","Annotated":241,"Significant":23,"Expected":14.56,"Rank in p.value_classic":878,"p.value_elim":0.45432,"p.value_classic":0.01993,"genes":"AURKB,BIRC5,BUB1B,CDC6,CDK1,CENPF,FEN1,GCH1,MAD2L1,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,PKIB,PML,RMI2,SPC24,SPC25,TAL1,TOP2A,XRN1,ZWINT"} {"GO.ID":"GO:0045637","Term":"regulation of myeloid cell differentiation","Annotated":176,"Significant":18,"Expected":10.63,"Rank in p.value_classic":877,"p.value_elim":0.45509,"p.value_classic":0.01985,"genes":"B2M,CD101,CD74,CEACAM1,CSF1,DLL1,FAXDC2,HLA-DRB1,IRF7,KITLG,LILRB3,LYN,SCIN,STAT1,TAL1,TESC,TNFAIP6,TNFRSF11A"} {"GO.ID":"GO:0043086","Term":"negative regulation of catalytic activity","Annotated":351,"Significant":22,"Expected":21.2,"Rank in p.value_classic":2646,"p.value_elim":0.45537,"p.value_classic":0.46023,"genes":"AGT,AOC3,CARD16,CEACAM1,DEPTOR,DTNBP1,DTX3L,KLF4,KLRK1,LAMP3,LRP5,LRRK2,LYN,MAD2L1,MMP9,MVP,PARP3,PARP9,PKIB,PPM1E,SERPING1,WARS1"} {"GO.ID":"GO:0032787","Term":"monocarboxylic acid metabolic process","Annotated":466,"Significant":29,"Expected":28.14,"Rank in p.value_classic":2647,"p.value_elim":0.45563,"p.value_classic":0.46124,"genes":"ACOT4,ACSL1,APPL2,ATP8B1,BRCA1,C3,CD74,CEACAM1,CYP1A1,DHRS9,DSE,EDN1,EPHX1,GGT5,HSD3B7,HYI,IDO1,IL4I1,LPL,LTC4S,NAAA,NR4A3,OSBPL6,P2RX7,PDK4,PNPLA3,SGPL1,SLC2A6,SLC45A3"} {"GO.ID":"GO:0034764","Term":"positive regulation of transmembrane transport","Annotated":158,"Significant":19,"Expected":9.54,"Rank in p.value_classic":603,"p.value_elim":0.45662,"p.value_classic":0.00314,"genes":"ABCB1,ACSL1,ANK2,ATP1B2,C3,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ2,NR4A3,P2RX4,P2RX7,SRI,TESC,TRDN"} {"GO.ID":"GO:0043434","Term":"response to peptide hormone","Annotated":340,"Significant":25,"Expected":20.53,"Rank in p.value_classic":1765,"p.value_elim":0.45687,"p.value_classic":0.17853,"genes":"AGT,APPL2,CCNA2,CDC6,CEACAM1,CRHBP,EDN1,EGR2,GHRL,JAK2,JAK3,LRP5,LYN,NR4A3,PDE3B,PDK4,PID1,PNPLA3,PXN,SESN3,SOCS1,STAT1,STAT2,TNFRSF11A,TNFSF10"} {"GO.ID":"GO:0002367","Term":"cytokine production involved in immune response","Annotated":106,"Significant":20,"Expected":6.4,"Rank in p.value_classic":268,"p.value_elim":0.45705,"p.value_classic":4.6e-06,"genes":"B2M,BCL6,CD74,HLA-A,HLA-E,HLA-F,HLA-G,JAK3,LITAF,NOD2,NR4A3,P2RX7,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:0001914","Term":"regulation of T cell mediated cytotoxicity","Annotated":43,"Significant":16,"Expected":2.6,"Rank in p.value_classic":130,"p.value_elim":0.45717,"p.value_classic":1.5e-09,"genes":"B2M,CD1A,CD1C,CEACAM1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,P2RX7,TAP2"} {"GO.ID":"GO:0045582","Term":"positive regulation of T cell differentiation","Annotated":104,"Significant":15,"Expected":6.28,"Rank in p.value_classic":519,"p.value_elim":0.45741,"p.value_classic":0.00141,"genes":"ADAM8,BCL6,BTN2A2,CD74,CD80,CD83,CYLD,HLA-DRA,HLA-DRB1,HLA-G,IL12RB1,IL4I1,IL7,RIPK2,SOCS1"} {"GO.ID":"GO:0062013","Term":"positive regulation of small molecule metabolic process","Annotated":106,"Significant":7,"Expected":6.4,"Rank in p.value_classic":2645,"p.value_elim":0.45751,"p.value_classic":0.46017,"genes":"CD74,DAB2,NR4A3,P2RX7,PID1,PMAIP1,SLC45A3"} {"GO.ID":"GO:0015711","Term":"organic anion transport","Annotated":298,"Significant":22,"Expected":18,"Rank in p.value_classic":1848,"p.value_elim":0.45761,"p.value_classic":0.19181,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ANKH,ATP8B1,CEACAM1,CTNS,DTNBP1,EDN1,KCNJ10,LRP5,P2RX4,P2RX7,RBP7,SERINC5,SLC11A1,SLC16A10,SLC2A6,SLC4A7,SLC6A12,TNFRSF11A"} {"GO.ID":"GO:0010243","Term":"response to organonitrogen compound","Annotated":820,"Significant":54,"Expected":49.52,"Rank in p.value_classic":2106,"p.value_elim":0.45924,"p.value_classic":0.26951,"genes":"AGT,APPL2,ASIC1,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CD40,CDC6,CDK1,CEACAM1,CRHBP,DERL3,DHFR,DTNBP1,EDN1,EGR2,FBXO6,GHRL,GNG2,ICAM1,JAK2,JAK3,KLF4,LPL,LRP5,LRRK2,LYN,MMP9,NOD2,NR4A3,P2RX4,P2RX7,PDE3B,PDK4,PID1,PNPLA3,PXN,RAPGEF2,RIPK2,SESN3,SOCS1,STAMBPL1,STAT1,STAT2,TGM2,THBD,TLR7,TNFRSF11A,TNFSF10,TYMS,VCAM1,XRN1"} {"GO.ID":"GO:0018212","Term":"peptidyl-tyrosine modification","Annotated":219,"Significant":31,"Expected":13.23,"Rank in p.value_classic":279,"p.value_elim":0.4596,"p.value_classic":8e-06,"genes":"AATK,AGT,BANK1,CCL5,CD40,CD74,CD80,CLEC6A,ENPP2,HBEGF,HGF,IL12A,IL15,IL22RA2,IL31RA,IL7,JAK2,JAK3,KITLG,LYN,MVP,NCF1,NOD2,NRP1,OSM,PARP14,PARP9,RIPK2,SOCS1,TNFRSF14,TNFSF18"} {"GO.ID":"GO:0097028","Term":"dendritic cell differentiation","Annotated":40,"Significant":10,"Expected":2.42,"Rank in p.value_classic":361,"p.value_elim":0.45974,"p.value_classic":0.0001,"genes":"BATF2,BATF3,HLA-B,HLA-G,IRF4,LYN,RELB,TMEM176A,TMEM176B,UBD"} {"GO.ID":"GO:1903432","Term":"regulation of TORC1 signaling","Annotated":90,"Significant":6,"Expected":5.44,"Rank in p.value_classic":2648,"p.value_elim":0.46011,"p.value_classic":0.46256,"genes":"CASTOR1,CTNS,DEPTOR,PIM1,SESN3,STAMBPL1"} {"GO.ID":"GO:0006629","Term":"lipid metabolic process","Annotated":1044,"Significant":64,"Expected":63.05,"Rank in p.value_classic":2732,"p.value_elim":0.46064,"p.value_classic":0.46924,"genes":"ACOT4,ACSL1,APOL1,APOL2,APOL4,APPL2,ATP8B1,BRCA1,C3,CD74,CDS1,CEACAM1,CISH,CYP1A1,DAB2,DGAT2,DHRS3,DHRS9,EDN1,ENPP2,EPHX1,FAXDC2,G6PC1,GAL3ST4,GGT5,GK,GOLM1,GPR31,HCAR2,HSD11B1,HSD3B7,IL1RN,LACTB,LCLAT1,LPL,LRP5,LTC4S,NAAA,NR4A3,OSBPL6,P2RX7,PCYT1A,PDE3B,PDK4,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PNPLA3,RNF213,SCARF1,SERINC5,SGPL1,SLC45A3,SOAT1,SOCS1,TMEM150A,TNFAIP8L3,TTC39B"} {"GO.ID":"GO:0033500","Term":"carbohydrate homeostasis","Annotated":188,"Significant":12,"Expected":11.35,"Rank in p.value_classic":2723,"p.value_elim":0.46096,"p.value_classic":0.46451,"genes":"APPL2,G6PC1,GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,PDK4,SESN3,SIDT2,SRI,SUCNR1"} {"GO.ID":"GO:0030178","Term":"negative regulation of Wnt signaling pathway","Annotated":139,"Significant":9,"Expected":8.39,"Rank in p.value_classic":2722,"p.value_elim":0.4613,"p.value_classic":0.46435,"genes":"AMER1,CYLD,DAB2,DKK2,KREMEN1,PTPRU,RNF213,SOX17,TRABD2A"} {"GO.ID":"GO:0033077","Term":"T cell differentiation in thymus","Annotated":74,"Significant":5,"Expected":4.47,"Rank in p.value_classic":2724,"p.value_elim":0.46282,"p.value_classic":0.46505,"genes":"ADAM8,B2M,CD28,CD74,RIPK2"} {"GO.ID":"GO:0071230","Term":"cellular response to amino acid stimulus","Annotated":74,"Significant":5,"Expected":4.47,"Rank in p.value_classic":2725,"p.value_elim":0.46282,"p.value_classic":0.46505,"genes":"CASTOR1,PNPLA3,SESN3,SOCS1,STAMBPL1"} {"GO.ID":"GO:0005513","Term":"detection of calcium ion","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2650,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SYT1"} {"GO.ID":"GO:0009120","Term":"deoxyribonucleoside metabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2651,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TK1"} {"GO.ID":"GO:1901678","Term":"iron coordination entity transport","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2652,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"FLVCR2"} {"GO.ID":"GO:0051917","Term":"regulation of fibrinolysis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2653,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"THBD"} {"GO.ID":"GO:1905208","Term":"negative regulation of cardiocyte differentiation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2654,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DLL1"} {"GO.ID":"GO:0098915","Term":"membrane repolarization during ventricular cardiac muscle cell action potential","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2655,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"KCNE5"} {"GO.ID":"GO:0010273","Term":"detoxification of copper ion","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2656,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"MT2A"} {"GO.ID":"GO:0061909","Term":"autophagosome-lysosome fusion","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2657,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ATP13A2"} {"GO.ID":"GO:1903911","Term":"positive regulation of receptor clustering","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2658,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TNFAIP6"} {"GO.ID":"GO:0006995","Term":"cellular response to nitrogen starvation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2659,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"MAP1LC3C"} {"GO.ID":"GO:0034351","Term":"negative regulation of glial cell apoptotic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2660,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DLL1"} {"GO.ID":"GO:0044314","Term":"protein K27-linked ubiquitination","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2661,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"UBE2T"} {"GO.ID":"GO:0010887","Term":"negative regulation of cholesterol storage","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2662,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TTC39B"} {"GO.ID":"GO:0010820","Term":"positive regulation of T cell chemotaxis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2663,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"CCL5"} {"GO.ID":"GO:0060788","Term":"ectodermal placode formation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2664,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDA"} {"GO.ID":"GO:0008063","Term":"Toll signaling pathway","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2665,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"NLRP12"} {"GO.ID":"GO:1990169","Term":"stress response to copper ion","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2666,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"MT2A"} {"GO.ID":"GO:0071028","Term":"nuclear mRNA surveillance","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2667,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"XRN1"} {"GO.ID":"GO:0070862","Term":"negative regulation of protein exit from endoplasmic reticulum","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2668,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DERL3"} {"GO.ID":"GO:0140719","Term":"constitutive heterochromatin formation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2669,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"HELLS"} {"GO.ID":"GO:0050802","Term":"circadian sleep/wake cycle, sleep","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2670,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"GHRL"} {"GO.ID":"GO:2000392","Term":"regulation of lamellipodium morphogenesis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2671,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ENPP2"} {"GO.ID":"GO:0022410","Term":"circadian sleep/wake cycle process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2672,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"GHRL"} {"GO.ID":"GO:1990253","Term":"cellular response to leucine starvation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2673,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SESN3"} {"GO.ID":"GO:0042448","Term":"progesterone metabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2674,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DHRS9"} {"GO.ID":"GO:0003157","Term":"endocardium development","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2675,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SOX17"} {"GO.ID":"GO:0006086","Term":"acetyl-CoA biosynthetic process from pyruvate","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2676,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"PDK4"} {"GO.ID":"GO:0072376","Term":"protein activation cascade","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2677,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"THBD"} {"GO.ID":"GO:0014842","Term":"regulation of skeletal muscle satellite cell proliferation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2678,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"JAK2"} {"GO.ID":"GO:0060628","Term":"regulation of ER to Golgi vesicle-mediated transport","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2679,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"LRRK2"} {"GO.ID":"GO:0051386","Term":"regulation of neurotrophin TRK receptor signaling pathway","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2680,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"AGT"} {"GO.ID":"GO:0071389","Term":"cellular response to mineralocorticoid stimulus","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2681,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDN1"} {"GO.ID":"GO:0010919","Term":"regulation of inositol phosphate biosynthetic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2682,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"PLEK"} {"GO.ID":"GO:0061309","Term":"cardiac neural crest cell development involved in outflow tract morphogenesis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2683,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDN1"} {"GO.ID":"GO:0030953","Term":"astral microtubule organization","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2684,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"LIMK2"} {"GO.ID":"GO:0071468","Term":"cellular response to acidic pH","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2685,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"PKD1L3"} {"GO.ID":"GO:0007379","Term":"segment specification","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2686,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DLL1"} {"GO.ID":"GO:0055012","Term":"ventricular cardiac muscle cell differentiation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2687,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"CDK1"} {"GO.ID":"GO:0042749","Term":"regulation of circadian sleep/wake cycle","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2688,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"GHRL"} {"GO.ID":"GO:0046322","Term":"negative regulation of fatty acid oxidation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2689,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"APPL2"} {"GO.ID":"GO:1990504","Term":"dense core granule exocytosis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2690,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"CADPS2"} {"GO.ID":"GO:0043562","Term":"cellular response to nitrogen levels","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2691,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"MAP1LC3C"} {"GO.ID":"GO:0036462","Term":"TRAIL-activated apoptotic signaling pathway","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2692,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ATF3"} {"GO.ID":"GO:2000756","Term":"regulation of peptidyl-lysine acetylation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2693,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"PML"} {"GO.ID":"GO:0036446","Term":"myofibroblast differentiation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2694,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"RXFP1"} {"GO.ID":"GO:0001765","Term":"membrane raft assembly","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2695,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"S100A10"} {"GO.ID":"GO:0016185","Term":"synaptic vesicle budding from presynaptic endocytic zone membrane","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2696,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DNM1"} {"GO.ID":"GO:0002887","Term":"negative regulation of myeloid leukocyte mediated immunity","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2697,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"CX3CR1"} {"GO.ID":"GO:0046160","Term":"heme a metabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2698,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ALAS1"} {"GO.ID":"GO:0098779","Term":"positive regulation of mitophagy in response to mitochondrial depolarization","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2699,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"OPTN"} {"GO.ID":"GO:0006104","Term":"succinyl-CoA metabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2700,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ACOT4"} {"GO.ID":"GO:0001553","Term":"luteinization","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2701,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SGPL1"} {"GO.ID":"GO:0031666","Term":"positive regulation of lipopolysaccharide-mediated signaling pathway","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2702,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SCIMP"} {"GO.ID":"GO:0031650","Term":"regulation of heat generation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2703,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TNFRSF11A"} {"GO.ID":"GO:0031645","Term":"negative regulation of nervous system process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2704,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TNFRSF21"} {"GO.ID":"GO:1901298","Term":"regulation of hydrogen peroxide-mediated programmed cell death","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2705,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"HGF"} {"GO.ID":"GO:0051593","Term":"response to folic acid","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2706,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TYMS"} {"GO.ID":"GO:2000644","Term":"regulation of receptor catabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2707,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"DTX3L"} {"GO.ID":"GO:0001660","Term":"fever generation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2708,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"TNFRSF11A"} {"GO.ID":"GO:0086100","Term":"endothelin receptor signaling pathway","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2709,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDN1"} {"GO.ID":"GO:0043951","Term":"negative regulation of cAMP-mediated signaling","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2710,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"PDE3B"} {"GO.ID":"GO:0006784","Term":"heme A biosynthetic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2711,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ALAS1"} {"GO.ID":"GO:0045793","Term":"positive regulation of cell size","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2712,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDN1"} {"GO.ID":"GO:0048671","Term":"negative regulation of collateral sprouting","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2713,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"FSTL4"} {"GO.ID":"GO:0071697","Term":"ectodermal placode morphogenesis","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2714,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"EDA"} {"GO.ID":"GO:0060049","Term":"regulation of protein glycosylation","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2715,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"IL15"} {"GO.ID":"GO:0051610","Term":"serotonin uptake","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2716,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SLC18A1"} {"GO.ID":"GO:0015838","Term":"amino-acid betaine transport","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2717,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"SLC6A12"} {"GO.ID":"GO:0140059","Term":"dendrite arborization","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2718,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"NRP1"} {"GO.ID":"GO:0045838","Term":"positive regulation of membrane potential","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2719,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"CTNS"} {"GO.ID":"GO:0046501","Term":"protoporphyrinogen IX metabolic process","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2720,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"ALAS1"} {"GO.ID":"GO:0014051","Term":"gamma-aminobutyric acid secretion","Annotated":10,"Significant":1,"Expected":0.6,"Rank in p.value_classic":2721,"p.value_elim":0.46289,"p.value_classic":0.46377,"genes":"P2RX7"} {"GO.ID":"GO:0032504","Term":"multicellular organism reproduction","Annotated":616,"Significant":38,"Expected":37.2,"Rank in p.value_classic":2737,"p.value_elim":0.46387,"p.value_classic":0.47037,"genes":"ADGB,APOL2,BCL2L11,BCL6,CXADR,CYP1A1,DAZL,DMC1,EDN1,GHRL,HORMAD1,IGF2R,LIMK2,LRRK2,MEIKIN,MERTK,NCAPH,NDC80,NPM2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PROK2,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TMEM119,TNFAIP6,TOP2A,TYRO3,ZMYND15"} {"GO.ID":"GO:0001890","Term":"placenta development","Annotated":123,"Significant":8,"Expected":7.43,"Rank in p.value_classic":2726,"p.value_elim":0.46423,"p.value_classic":0.4671,"genes":"ASCL2,CCNF,E2F8,EPAS1,GHRL,HTRA1,PCDH12,PLCD3"} {"GO.ID":"GO:0021953","Term":"central nervous system neuron differentiation","Annotated":123,"Significant":8,"Expected":7.43,"Rank in p.value_classic":2727,"p.value_elim":0.46423,"p.value_classic":0.4671,"genes":"B2M,C21orf91,EPHB3,MDGA1,NRP1,RAPGEF2,SPTBN4,TAL1"} {"GO.ID":"GO:0000724","Term":"double-strand break repair via homologous recombination","Annotated":168,"Significant":17,"Expected":10.15,"Rank in p.value_classic":945,"p.value_elim":0.46459,"p.value_classic":0.02537,"genes":"BRCA1,CDC45,DMC1,FEN1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RAD54B,RAD54L,RECQL4,RMI2,TONSL,UHRF1,XRCC2"} {"GO.ID":"GO:0044818","Term":"mitotic G2/M transition checkpoint","Annotated":52,"Significant":7,"Expected":3.14,"Rank in p.value_classic":1033,"p.value_elim":0.46541,"p.value_classic":0.03573,"genes":"BRCA1,CDC6,CDK1,CLSPN,DTL,ORC1,TICRR"} {"GO.ID":"GO:0007160","Term":"cell-matrix adhesion","Annotated":205,"Significant":13,"Expected":12.38,"Rank in p.value_classic":2731,"p.value_elim":0.46546,"p.value_classic":0.46916,"genes":"BCL2L11,BCL6,CSF1,EDA,FAM107A,FGL1,ITGA7,ITGB5,LYVE1,NRP1,ONECUT2,S100A10,VCAM1"} {"GO.ID":"GO:0097009","Term":"energy homeostasis","Annotated":58,"Significant":4,"Expected":3.5,"Rank in p.value_classic":2728,"p.value_elim":0.46561,"p.value_classic":0.46759,"genes":"APPL2,DLL1,NR4A3,SLC12A3"} {"GO.ID":"GO:0034605","Term":"cellular response to heat","Annotated":58,"Significant":4,"Expected":3.5,"Rank in p.value_classic":2729,"p.value_elim":0.46561,"p.value_classic":0.46759,"genes":"CXCL10,HSBP1L1,LYN,TFEC"} {"GO.ID":"GO:0032507","Term":"maintenance of protein location in cell","Annotated":58,"Significant":4,"Expected":3.5,"Rank in p.value_classic":2730,"p.value_elim":0.46561,"p.value_classic":0.46759,"genes":"PML,SCIN,SYNE1,TMSB10"} {"GO.ID":"GO:0034103","Term":"regulation of tissue remodeling","Annotated":61,"Significant":9,"Expected":3.68,"Rank in p.value_classic":750,"p.value_elim":0.46673,"p.value_classic":0.01049,"genes":"ADAM8,CD38,CEACAM1,IL15,P2RX7,PDK4,S1PR1,TMEM119,TNFRSF11A"} {"GO.ID":"GO:0030282","Term":"bone mineralization","Annotated":107,"Significant":7,"Expected":6.46,"Rank in p.value_classic":2735,"p.value_elim":0.46739,"p.value_classic":0.47006,"genes":"ANKH,COMP,P2RX7,S1PR1,SBNO2,SNX10,TMEM119"} {"GO.ID":"GO:0010811","Term":"positive regulation of cell-substrate adhesion","Annotated":107,"Significant":7,"Expected":6.46,"Rank in p.value_classic":2736,"p.value_elim":0.46739,"p.value_classic":0.47006,"genes":"AGR2,CSF1,DAB2,JAK2,NRP1,RSU1,S100A10"} {"GO.ID":"GO:0009116","Term":"nucleoside metabolic process","Annotated":45,"Significant":7,"Expected":2.72,"Rank in p.value_classic":839,"p.value_elim":0.46743,"p.value_classic":0.01739,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4,PRTFDC1,TK1,TYMP"} {"GO.ID":"GO:0040007","Term":"growth","Annotated":749,"Significant":46,"Expected":45.24,"Rank in p.value_classic":2755,"p.value_elim":0.468,"p.value_classic":0.47522,"genes":"AGR2,AGT,ATF5,BCL2L11,BCL6,BRCA1,CAMK2D,CD38,CDK1,CDKN2C,CEACAM1,CISH,COLQ,COMP,CSF1,DAB2,DLL1,EDN1,FAM107A,FSTL4,G6PC1,GHRL,GINS1,HBEGF,HESX1,IL7,JADE2,KIF26A,MT2A,NCAPG2,NPR1,NRCAM,NRN1,NRP1,PIM1,PML,S1PR1,SELENOP,SEMA6B,SGPL1,SOX17,SPTBN4,SYT1,TNFAIP6,TYMS,XRCC2"} {"GO.ID":"GO:0007275","Term":"multicellular organism development","Annotated":3662,"Significant":251,"Expected":221.17,"Rank in p.value_classic":732,"p.value_elim":0.46821,"p.value_classic":0.0088,"genes":"AATK,ACOD1,ADAM8,AGR2,AGT,AIM2,AMER1,AMOT,ANK2,ANKH,ANTXR1,APPL2,ASB2,ASCL2,ATF5,ATP1B2,ATP8B1,AURKB,B2M,BCL2L11,BCL6,BHLHE41,BRCA1,BTN2A2,C21orf91,C3,C3orf70,CASP7,CASZ1,CD101,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CDKN2C,CEACAM1,CELSR1,CENPF,CENPU,CHAC1,CHMP4C,CHRD,CIBAR1,COL9A2,COLQ,COMP,CSF1,CTLA4,CTNS,CX3CR1,CXADR,CXCL10,CXCR3,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DHFR,DHRS3,DLL1,DMC1,DNAAF1,DTNBP1,DYNLT1,E2F1,E2F2,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,EPOP,EXO1,FAXDC2,FGL1,FGL2,FLT3LG,FSTL4,GABRA3,GCNT3,GFRA2,GHRL,GINS1,GLDN,GLUL,GPR183,GRIN3A,HAPLN3,HELLS,HESX1,HGF,HLA-B,HLA-DOA,HLA-DRA,HLA-DRB1,HLA-E,HLA-G,HORMAD1,HSD11B1,IDO1,IFT122,IGF2R,IL12A,IL12RB1,IL15,IL15RA,IL1RN,IL27,IL4I1,IL7,INA,IRF1,IRF4,IRF7,ITGA7,ITGB5,JAK2,JAK3,KCNJ10,KIF26A,KITLG,KLF4,KREMEN1,LAG3,LAMB3,LGI2,LILRB3,LIMK2,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MARCKSL1,MDGA1,MERTK,MICAL2,MIR503,MMD,MMP9,MTSS1,NCAPG2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRN1,NRP1,NYAP2,OAS2,OLIG1,ONECUT2,OVOL1,P2RX4,P2RX7,PADI2,PARP3,PCDH12,PCDHGC3,PDCD1,PDE3B,PIM1,PKD1L3,PLAAT3,PLAAT4,PLCD3,PLPP4,PLXNA2,PML,POLB,PRKX,PROK2,PTGER4,RAPGEF2,RASGRF1,RHOBTB3,RIPK2,RNF213,RRM2,RTN4RL1,RXFP1,S100A10,S1PR1,SAT1,SCARF1,SCIN,SCO2,SDC2,SELENOP,SEMA6B,SEPTIN4,SERINC5,SGPL1,SH3PXD2A,SIDT2,SLAMF8,SLC45A3,SLC4A7,SNX10,SOBP,SOCS1,SOX17,SPTBN4,SRI,SSBP3,SSTR2,STAP1,STAT1,STMN1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TBX21,TESC,TGM2,THBS2,TIFAB,TMEM119,TMEM176A,TMEM176B,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF10,TOP2A,TYMP,TYMS,TYRO3,UNG,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,WWP1,XRCC2,XYLT1,ZC3H12A"} {"GO.ID":"GO:0051965","Term":"positive regulation of synapse assembly","Annotated":42,"Significant":3,"Expected":2.54,"Rank in p.value_classic":2733,"p.value_elim":0.4683,"p.value_classic":0.46999,"genes":"EPHB3,GHRL,THBS2"} {"GO.ID":"GO:0050732","Term":"negative regulation of peptidyl-tyrosine phosphorylation","Annotated":42,"Significant":3,"Expected":2.54,"Rank in p.value_classic":2734,"p.value_elim":0.4683,"p.value_classic":0.46999,"genes":"MVP,PARP14,SOCS1"} {"GO.ID":"GO:0006979","Term":"response to oxidative stress","Annotated":337,"Significant":21,"Expected":20.35,"Rank in p.value_classic":2754,"p.value_elim":0.4688,"p.value_classic":0.47357,"genes":"AIFM2,ATP13A2,CD38,CDK1,DHFR,EDN1,EPAS1,GCH1,HGF,IL18BP,JAK2,KLF4,LRRK2,MMP9,NCF1,PXN,SELENOP,SESN3,STAT1,VRK2,ZC3H12A"} {"GO.ID":"GO:0045860","Term":"positive regulation of protein kinase activity","Annotated":222,"Significant":14,"Expected":13.41,"Rank in p.value_classic":2753,"p.value_elim":0.46955,"p.value_classic":0.4734,"genes":"AGT,CCL5,CD40,CLSPN,CSF1,EDN1,JAK2,LRRK2,MMD,NCF1,RALB,RAPGEF2,SLC11A1,TNFRSF11A"} {"GO.ID":"GO:0006699","Term":"bile acid biosynthetic process","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2738,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"HSD3B7,OSBPL6"} {"GO.ID":"GO:0045671","Term":"negative regulation of osteoclast differentiation","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2739,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"LILRB3,TNFAIP6"} {"GO.ID":"GO:0030212","Term":"hyaluronan metabolic process","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2740,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"LYVE1,TNFAIP6"} {"GO.ID":"GO:0060795","Term":"cell fate commitment involved in formation of primary germ layer","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2741,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"KLF4,SOX17"} {"GO.ID":"GO:0010575","Term":"positive regulation of vascular endothelial growth factor production","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2742,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"BRCA1,C3"} {"GO.ID":"GO:0034138","Term":"toll-like receptor 3 signaling pathway","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2743,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"COLEC12,SCIMP"} {"GO.ID":"GO:0009649","Term":"entrainment of circadian clock","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2744,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"BMAL2,PML"} {"GO.ID":"GO:0033198","Term":"response to ATP","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2745,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"P2RX4,P2RX7"} {"GO.ID":"GO:0042401","Term":"biogenic amine biosynthetic process","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2746,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"GCH1,SAT1"} {"GO.ID":"GO:0048333","Term":"mesodermal cell differentiation","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2747,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"KLF4,TAL1"} {"GO.ID":"GO:0086005","Term":"ventricular cardiac muscle cell action potential","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2748,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"ANK2,KCNE5"} {"GO.ID":"GO:1902410","Term":"mitotic cytokinetic process","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2749,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"CHMP4C,IQGAP3"} {"GO.ID":"GO:1904752","Term":"regulation of vascular associated smooth muscle cell migration","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2750,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"MIR503,NR4A3"} {"GO.ID":"GO:0045830","Term":"positive regulation of isotype switching","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2751,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"CD28,TBX21"} {"GO.ID":"GO:0021952","Term":"central nervous system projection neuron axonogenesis","Annotated":26,"Significant":2,"Expected":1.57,"Rank in p.value_classic":2752,"p.value_elim":0.47004,"p.value_classic":0.47138,"genes":"EPHB3,SPTBN4"} {"GO.ID":"GO:0060047","Term":"heart contraction","Annotated":180,"Significant":20,"Expected":10.87,"Rank in p.value_classic":691,"p.value_elim":0.47058,"p.value_classic":0.00611,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CXADR,EDN1,EPAS1,GCH1,GJD3,HBEGF,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SPTBN4,SRI,TRDN,ZC3H12A"} {"GO.ID":"GO:0050769","Term":"positive regulation of neurogenesis","Annotated":206,"Significant":13,"Expected":12.44,"Rank in p.value_classic":2757,"p.value_elim":0.47258,"p.value_classic":0.47629,"genes":"CX3CR1,CYSLTR1,EGR2,HAPLN3,LTA,LYN,NRP1,PLXNA2,TGM2,VCAN,VEGFC,WDR62,XRCC2"} {"GO.ID":"GO:0120161","Term":"regulation of cold-induced thermogenesis","Annotated":124,"Significant":8,"Expected":7.49,"Rank in p.value_classic":2756,"p.value_elim":0.4734,"p.value_classic":0.47629,"genes":"ACSL1,APPL2,EPAS1,G0S2,GHRL,IL15,IRF4,JAK2"} {"GO.ID":"GO:0099587","Term":"inorganic ion import across plasma membrane","Annotated":75,"Significant":5,"Expected":4.53,"Rank in p.value_classic":2758,"p.value_elim":0.47465,"p.value_classic":0.47689,"genes":"ATP1B2,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"GO.ID":"GO:0002793","Term":"positive regulation of peptide secretion","Annotated":75,"Significant":5,"Expected":4.53,"Rank in p.value_classic":2759,"p.value_elim":0.47465,"p.value_classic":0.47689,"genes":"CD38,GHRL,HLA-DRB1,JAK2,SRI"} {"GO.ID":"GO:0008625","Term":"extrinsic apoptotic signaling pathway via death domain receptors","Annotated":75,"Significant":5,"Expected":4.53,"Rank in p.value_classic":2760,"p.value_elim":0.47465,"p.value_classic":0.47689,"genes":"ATF3,BRCA1,HGF,ICAM1,PMAIP1"} {"GO.ID":"GO:0098659","Term":"inorganic cation import across plasma membrane","Annotated":75,"Significant":5,"Expected":4.53,"Rank in p.value_classic":2761,"p.value_elim":0.47465,"p.value_classic":0.47689,"genes":"ATP1B2,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"GO.ID":"GO:0051726","Term":"regulation of cell cycle","Annotated":968,"Significant":81,"Expected":58.46,"Rank in p.value_classic":527,"p.value_elim":0.47522,"p.value_classic":0.00153,"genes":"ANLN,APPL2,ATF5,AURKB,BCL2L11,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDKL1,CDKN2C,CDT1,CENPF,CHMP4C,CLSPN,CYLD,CYP1A1,DAZL,DTL,DTX3L,E2F1,E2F2,E2F8,EDN1,EME1,FAM107A,FBXO6,FEN1,GADD45B,GTSE1,HLA-G,HORMAD1,IRF1,JADE2,KIF11,KIF23,KLF4,LRP5,MAD2L1,MIR503,MKI67,MUC1,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,ORC1,OVOL1,PARP3,PARP9,PCLAF,PKMYT1,PLSCR1,PML,PRC1,PSME1,PSME2,RMI2,RRM2,SPC24,SPC25,TAL1,TICRR,UBD,WDR62,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0051247","Term":"positive regulation of protein metabolic process","Annotated":1064,"Significant":81,"Expected":64.26,"Rank in p.value_classic":834,"p.value_elim":0.47522,"p.value_classic":0.01678,"genes":"ADAM8,AGT,AIM2,AMER1,BANK1,C3,CCL5,CD28,CD40,CD74,CD80,CDH5,CLEC6A,CLSPN,CSF1,CTSL,CTSS,CX3CR1,DAB2,DAZL,DTL,DTNBP1,EDN1,ENPP2,FAM107A,FAM20A,FAS,FAXDC2,GRAMD4,GSAP,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IQGAP3,JAK2,KITLG,KLF4,LILRA2,LIMK2,LRRK2,LYN,MEFV,MMD,MMP9,NCF1,NLRP12,NMI,NOD2,NRP1,NUB1,OSM,P2RX7,PARP14,PARP9,PMAIP1,PML,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RIPK2,S100A10,SAMD4A,SEPTIN4,SLC11A1,SOAT1,SOX17,TANK,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TRABD2A,UHRF1,VEGFC,ZC3H12A"} {"GO.ID":"GO:0008219","Term":"cell death","Annotated":1654,"Significant":134,"Expected":99.89,"Rank in p.value_classic":384,"p.value_elim":0.47577,"p.value_classic":0.00017,"genes":"ADAM8,AGT,AIFM2,AIM2,ATF3,ATF5,ATP13A2,AURKB,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BUB1B,C3orf38,CAMK2D,CARD16,CASP4,CASP7,CCL5,CD274,CD28,CD38,CD40,CD74,CDCA7,CDH5,CDK1,CHAC1,COMP,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCR3,CYLD,DAB2,DEPTOR,DLL1,DRAM1,E2F1,E2F2,EBF4,EDN1,FAS,G0S2,GADD45B,GBP1,GBP2,GBP3,GBP5,GCH1,GHRL,GIMAP8,GRAMD4,GSDMA,GSDMD,HCAR2,HELLS,HGF,HLA-G,HTRA1,ICAM1,IDO1,IFI27,IFIT2,IFIT3,IGF2R,IL12A,IL31RA,IL7,IRF1,IRF7,JAK2,JAK3,KITLG,KLF4,KREMEN1,LAMP3,LRP5,LRRK2,LTA,LYN,MAD2L1,MCM2,MEFV,MERTK,MMP9,MUC1,MYBL2,NLRP12,NOD2,NRP1,OPTN,P2RX4,P2RX7,PCDHGC3,PDCD1,PDK4,PIM1,PLSCR1,PMAIP1,PML,POLB,PROK2,RALB,RAPGEF2,RIPK2,SCIN,SEPTIN4,SGPL1,STAT1,SYNE1,TGM2,TIFAB,TMEM109,TNFAIP8L3,TNFRSF21,TNFSF10,TNFSF18,TOP2A,TRIM69,TYRO3,UBD,UNG,USP53,XAF1,XKR6,XRCC2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0002009","Term":"morphogenesis of an epithelium","Annotated":421,"Significant":26,"Expected":25.43,"Rank in p.value_classic":2763,"p.value_elim":0.47714,"p.value_classic":0.48249,"genes":"AGT,ASB2,CEACAM1,CELSR1,CSF1,CTNS,CXCL10,DLL1,DNAAF1,EDN1,HBEGF,HESX1,HGF,IFT122,ITGB5,KLF4,LRP5,MICAL2,MTSS1,NRP1,PML,PRKX,SOX17,STAT1,TGM2,VEGFC"} {"GO.ID":"GO:0007423","Term":"sensory organ development","Annotated":421,"Significant":26,"Expected":25.43,"Rank in p.value_classic":2764,"p.value_elim":0.47714,"p.value_classic":0.48249,"genes":"ASCL2,ATP8B1,BCL2L11,C1QTNF5,CCNA2,CTNS,CYP1A1,DLL1,DTNBP1,EDN1,HESX1,IFT122,KLF4,LIMK2,LRP5,MAF,MCM2,MERTK,MYO7B,NRP1,OLIG1,PLAAT3,SCO2,SLC4A7,SOBP,TIFAB"} {"GO.ID":"GO:0001817","Term":"regulation of cytokine production","Annotated":647,"Significant":99,"Expected":39.08,"Rank in p.value_classic":27,"p.value_elim":0.4776,"p.value_classic":2.7e-18,"genes":"ACOD1,ADAM8,AGT,AIM2,APPL2,B2M,BANK1,BCL6,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CARD16,CD274,CD28,CD74,CD80,CD83,CEACAM1,CLEC6A,CLEC9A,CX3CR1,CYLD,DLL1,FCN1,GBP1,GBP5,GBP7,GHRL,GSDMD,HGF,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL7,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KLF4,KLRK1,LAG3,LILRA2,LITAF,LPL,LRRK2,LTA,LYN,MCOLN2,MEFV,MERTK,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OSM,P2RX7,PDCD1LG2,PDE4B,PML,PTGER4,RELB,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,STAT1,TANK,TBX21,TICAM2,TLR5,TLR7,TLR8,TNFRSF14,TNFRSF21,XAF1,ZC3H12A"} {"GO.ID":"GO:0050771","Term":"negative regulation of axonogenesis","Annotated":59,"Significant":4,"Expected":3.56,"Rank in p.value_classic":2762,"p.value_elim":0.47897,"p.value_classic":0.48096,"genes":"DAB1,FSTL4,NRP1,SEMA6B"} {"GO.ID":"GO:0065004","Term":"protein-DNA complex assembly","Annotated":174,"Significant":11,"Expected":10.51,"Rank in p.value_classic":2765,"p.value_elim":0.47927,"p.value_classic":0.48268,"genes":"BAZ1A,CDC45,CDT1,CENPF,CENPK,CHAF1B,DMC1,H2BC21,HJURP,MCM2,OIP5"} {"GO.ID":"GO:0016358","Term":"dendrite development","Annotated":207,"Significant":13,"Expected":12.5,"Rank in p.value_classic":2766,"p.value_elim":0.47968,"p.value_classic":0.48341,"genes":"C21orf91,DAB1,DTNBP1,EPHB3,FSTL4,GHRL,GRIN3A,LRRK2,NRP1,RAPGEF2,SCARF1,SDC2,SYNE1"} {"GO.ID":"GO:0002065","Term":"columnar/cuboidal epithelial cell differentiation","Annotated":92,"Significant":6,"Expected":5.56,"Rank in p.value_classic":2767,"p.value_elim":0.48149,"p.value_classic":0.48398,"genes":"AGR2,DLL1,IL31RA,KLF4,SIDT2,TYMS"} {"GO.ID":"GO:0060996","Term":"dendritic spine development","Annotated":92,"Significant":6,"Expected":5.56,"Rank in p.value_classic":2768,"p.value_elim":0.48149,"p.value_classic":0.48398,"genes":"C21orf91,DTNBP1,EPHB3,FSTL4,GRIN3A,LRRK2"} {"GO.ID":"GO:0046660","Term":"female sex differentiation","Annotated":92,"Significant":6,"Expected":5.56,"Rank in p.value_classic":2769,"p.value_elim":0.48149,"p.value_classic":0.48398,"genes":"DMC1,KITLG,MERTK,SGPL1,TNFAIP6,TYRO3"} {"GO.ID":"GO:0035051","Term":"cardiocyte differentiation","Annotated":125,"Significant":8,"Expected":7.55,"Rank in p.value_classic":2770,"p.value_elim":0.48254,"p.value_classic":0.48544,"genes":"ASB2,CDK1,CXADR,DLL1,EDN1,SOX17,SYNE1,VCAM1"} {"GO.ID":"GO:0106106","Term":"cold-induced thermogenesis","Annotated":125,"Significant":8,"Expected":7.55,"Rank in p.value_classic":2771,"p.value_elim":0.48254,"p.value_classic":0.48544,"genes":"ACSL1,APPL2,EPAS1,G0S2,GHRL,IL15,IRF4,JAK2"} {"GO.ID":"GO:0033673","Term":"negative regulation of kinase activity","Annotated":158,"Significant":10,"Expected":9.54,"Rank in p.value_classic":2777,"p.value_elim":0.48302,"p.value_classic":0.48627,"genes":"AGT,CEACAM1,DEPTOR,DTNBP1,LRP5,LYN,MVP,PKIB,PPM1E,WARS1"} {"GO.ID":"GO:0030308","Term":"negative regulation of cell growth","Annotated":158,"Significant":10,"Expected":9.54,"Rank in p.value_classic":2778,"p.value_elim":0.48302,"p.value_classic":0.48627,"genes":"BCL6,BRCA1,CDKN2C,DAB2,FSTL4,NPR1,NRP1,PML,SEMA6B,SOX17"} {"GO.ID":"GO:0104004","Term":"cellular response to environmental stimulus","Annotated":290,"Significant":18,"Expected":17.51,"Rank in p.value_classic":2779,"p.value_elim":0.48302,"p.value_classic":0.48743,"genes":"ASIC1,AURKB,BRCA1,CD40,CDC25A,FAS,IRF1,KCNJ2,MMP9,PKD1L3,PTGER4,RELB,TANK,TIFAB,TLR5,TLR7,TLR8,TMEM109"} {"GO.ID":"GO:0060562","Term":"epithelial tube morphogenesis","Annotated":290,"Significant":18,"Expected":17.51,"Rank in p.value_classic":2780,"p.value_elim":0.48302,"p.value_classic":0.48743,"genes":"AGT,ASB2,CELSR1,CSF1,CTNS,CXCL10,DLL1,DNAAF1,EDN1,HESX1,IFT122,LRP5,MICAL2,MTSS1,NRP1,PML,PRKX,SOX17"} {"GO.ID":"GO:0071214","Term":"cellular response to abiotic stimulus","Annotated":290,"Significant":18,"Expected":17.51,"Rank in p.value_classic":2781,"p.value_elim":0.48302,"p.value_classic":0.48743,"genes":"ASIC1,AURKB,BRCA1,CD40,CDC25A,FAS,IRF1,KCNJ2,MMP9,PKD1L3,PTGER4,RELB,TANK,TIFAB,TLR5,TLR7,TLR8,TMEM109"} {"GO.ID":"GO:0043114","Term":"regulation of vascular permeability","Annotated":43,"Significant":3,"Expected":2.6,"Rank in p.value_classic":2772,"p.value_elim":0.484,"p.value_classic":0.48572,"genes":"CDH5,CEACAM1,NPR1"} {"GO.ID":"GO:0048599","Term":"oocyte development","Annotated":43,"Significant":3,"Expected":2.6,"Rank in p.value_classic":2773,"p.value_elim":0.484,"p.value_classic":0.48572,"genes":"DAZL,DMC1,EDN1"} {"GO.ID":"GO:0001541","Term":"ovarian follicle development","Annotated":43,"Significant":3,"Expected":2.6,"Rank in p.value_classic":2774,"p.value_elim":0.484,"p.value_classic":0.48572,"genes":"DMC1,KITLG,TNFAIP6"} {"GO.ID":"GO:0048663","Term":"neuron fate commitment","Annotated":43,"Significant":3,"Expected":2.6,"Rank in p.value_classic":2775,"p.value_elim":0.484,"p.value_classic":0.48572,"genes":"DLL1,EPOP,OLIG1"} {"GO.ID":"GO:0015695","Term":"organic cation transport","Annotated":43,"Significant":3,"Expected":2.6,"Rank in p.value_classic":2776,"p.value_elim":0.484,"p.value_classic":0.48572,"genes":"ADORA3,SLC6A12,STX1A"} {"GO.ID":"GO:0032392","Term":"DNA geometric change","Annotated":81,"Significant":13,"Expected":4.89,"Rank in p.value_classic":495,"p.value_elim":0.48438,"p.value_classic":0.00106,"genes":"CDC45,CHTF18,DSCC1,GINS1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RAD54B,RECQL4,TOP2A"} {"GO.ID":"GO:0035249","Term":"synaptic transmission, glutamatergic","Annotated":76,"Significant":5,"Expected":4.59,"Rank in p.value_classic":2782,"p.value_elim":0.48639,"p.value_classic":0.48865,"genes":"DTNBP1,GRIN3A,GRM8,LRRK2,SYT1"} {"GO.ID":"GO:0045833","Term":"negative regulation of lipid metabolic process","Annotated":76,"Significant":5,"Expected":4.59,"Rank in p.value_classic":2783,"p.value_elim":0.48639,"p.value_classic":0.48865,"genes":"APPL2,BRCA1,CEACAM1,HCAR2,PDE3B"} {"GO.ID":"GO:0070828","Term":"heterochromatin organization","Annotated":109,"Significant":7,"Expected":6.58,"Rank in p.value_classic":2784,"p.value_elim":0.48701,"p.value_classic":0.48971,"genes":"BAZ1A,BCL6,BRCA1,HELLS,TDRD9,UHRF1,ZNFX1"} {"GO.ID":"GO:0034204","Term":"lipid translocation","Annotated":45,"Significant":7,"Expected":2.72,"Rank in p.value_classic":840,"p.value_elim":0.48734,"p.value_classic":0.01739,"genes":"ABCB1,ANO4,ATP8B1,P2RX7,PLSCR1,PLSCR4,XKR6"} {"GO.ID":"GO:1901222","Term":"regulation of non-canonical NF-kappaB signal transduction","Annotated":81,"Significant":10,"Expected":4.89,"Rank in p.value_classic":901,"p.value_elim":0.48742,"p.value_classic":0.02358,"genes":"CYLD,EDA,EDN1,IFI35,LITAF,NLRP12,NMI,NOD2,TLR7,ZC3H12A"} {"GO.ID":"GO:0090307","Term":"mitotic spindle assembly","Annotated":70,"Significant":8,"Expected":4.23,"Rank in p.value_classic":1178,"p.value_elim":0.48877,"p.value_classic":0.05935,"genes":"AURKB,BIRC5,CHMP4C,KIF11,KIF23,MYBL2,PRC1,UHRF1"} {"GO.ID":"GO:0040011","Term":"locomotion","Annotated":1008,"Significant":86,"Expected":60.88,"Rank in p.value_classic":459,"p.value_elim":0.48883,"p.value_classic":0.0006,"genes":"ADAM8,ADORA3,AGT,AMOT,APPL2,ASCL2,ATP1B2,BCL6,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD274,CD300H,CD40,CD74,CDH5,CEACAM1,CHRD,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYSLTR1,DAB2,EDN1,ENPP2,FAM107A,GHRL,GLIPR2,GLUL,GPR183,HBEGF,HGF,HSD3B7,ICAM1,IFITM1,IL12A,JAK2,KIF26A,KITLG,KLF4,KLRK1,LRRK2,LYN,LYVE1,MIR503,MMP9,MTUS1,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,PADI2,PDE4B,PLXNA2,PRKX,PROK2,PTGER4,PTPRU,RAPGEF2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,STMN1,SUCNR1,TMSB10,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF18,TYMP,VCAM1,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0051983","Term":"regulation of chromosome segregation","Annotated":122,"Significant":19,"Expected":7.37,"Rank in p.value_classic":369,"p.value_elim":0.48963,"p.value_classic":0.00013,"genes":"AURKB,BIRC5,BUB1B,CDC6,CDK1,CENPF,HORMAD1,MAD2L1,MKI67,NCAPG,NCAPG2,NCAPH,NDC80,NUF2,PLSCR1,RMI2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:1900027","Term":"regulation of ruffle assembly","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2785,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"ICAM1,STAP1"} {"GO.ID":"GO:0043392","Term":"negative regulation of DNA binding","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2786,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"E2F1,JAK2"} {"GO.ID":"GO:0099563","Term":"modification of synaptic structure","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2787,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"CTTNBP2,DLGAP3"} {"GO.ID":"GO:0036010","Term":"protein localization to endosome","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2788,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"DTX3L,NRP1"} {"GO.ID":"GO:0051385","Term":"response to mineralocorticoid","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2789,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"EDN1,SLC12A3"} {"GO.ID":"GO:0017145","Term":"stem cell division","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2790,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"LBH,SOX17"} {"GO.ID":"GO:0043507","Term":"positive regulation of JUN kinase activity","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2791,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"EDN1,TNFRSF11A"} {"GO.ID":"GO:0060914","Term":"heart formation","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2792,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"PIM1,SOX17"} {"GO.ID":"GO:0006882","Term":"intracellular zinc ion homeostasis","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2793,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"ATP13A2,MT2A"} {"GO.ID":"GO:0009309","Term":"amine biosynthetic process","Annotated":27,"Significant":2,"Expected":1.63,"Rank in p.value_classic":2794,"p.value_elim":0.49002,"p.value_classic":0.49139,"genes":"GCH1,SAT1"} {"GO.ID":"GO:0010810","Term":"regulation of cell-substrate adhesion","Annotated":192,"Significant":12,"Expected":11.6,"Rank in p.value_classic":2795,"p.value_elim":0.49058,"p.value_classic":0.49416,"genes":"AGR2,BCL6,CSF1,DAB2,FAM107A,GBP1,JAK2,MIR503,NRP1,ONECUT2,RSU1,S100A10"} {"GO.ID":"GO:0098609","Term":"cell-cell adhesion","Annotated":747,"Significant":85,"Expected":45.12,"Rank in p.value_classic":146,"p.value_elim":0.49069,"p.value_classic":7.8e-09,"genes":"ADAM8,ASCL2,ATP1B2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CD93,CDH5,CEACAM1,CELSR1,COMP,CTLA4,CX3CR1,CXADR,CYLD,DAB1,EPHB3,F2RL3,FGL1,FGL2,GLDN,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,ICAM1,ICAM2,IDO1,IL12A,IL12RB1,IL15,IL1RN,IL4I1,IL7,IRF1,ITGA7,ITGB5,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LRP5,LYN,MDGA1,MPZL2,NOD2,NR4A3,NRCAM,PCDH12,PCDHGC3,PDCD1LG2,PLEK,PTPRU,RIPK2,SCARF1,SELL,SLAMF1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TSPAN32,TYRO3,VCAM1,ZC3H12A"} {"GO.ID":"GO:0006986","Term":"response to unfolded protein","Annotated":126,"Significant":8,"Expected":7.61,"Rank in p.value_classic":2798,"p.value_elim":0.49164,"p.value_classic":0.49454,"genes":"AGR2,ATF3,BCL2L11,CHAC1,COMP,DERL3,FBXO6,OPTN"} {"GO.ID":"GO:0050691","Term":"regulation of defense response to virus by host","Annotated":40,"Significant":10,"Expected":2.42,"Rank in p.value_classic":362,"p.value_elim":0.49198,"p.value_classic":0.0001,"genes":"AIM2,APOBEC3G,DTX3L,IL12RB1,IL15,IL27,PARP9,STAT1,TRIM22,ZC3H12A"} {"GO.ID":"GO:0042440","Term":"pigment metabolic process","Annotated":60,"Significant":4,"Expected":3.62,"Rank in p.value_classic":2796,"p.value_elim":0.4922,"p.value_classic":0.49421,"genes":"ALAS1,CTNS,OCA2,RAPGEF2"} {"GO.ID":"GO:0008344","Term":"adult locomotory behavior","Annotated":60,"Significant":4,"Expected":3.62,"Rank in p.value_classic":2797,"p.value_elim":0.4922,"p.value_classic":0.49421,"genes":"CTNS,DAB1,KCNJ10,SPTBN4"} {"GO.ID":"GO:0007010","Term":"cytoskeleton organization","Annotated":1252,"Significant":79,"Expected":75.62,"Rank in p.value_classic":2364,"p.value_elim":0.49399,"p.value_classic":0.35469,"genes":"ABLIM3,AMOT,ANK2,ANLN,ANTXR1,ASB2,ATF5,AURKB,BCL6,BIRC5,BRCA1,CCDC170,CCL13,CCL7,CCNF,CDH5,CDK1,CELSR1,CHMP4C,CXADR,CYLD,DNAAF1,DTNBP1,DYNLT1,EDN1,EML4,FAM107A,FGD5,FMNL2,FRMD3,FSCN1,GHRL,HLA-DRB1,INA,IQGAP3,ITGB5,JAK2,KIF11,KIF18B,KIF23,LIMK2,LRRC61,MAD2L1,MARCKSL1,MICAL2,MRAS,MSRB1,MTSS1,MYBL2,MYO7B,MYOZ2,NDC80,NRP1,NUF2,NUSAP1,P2RX7,PARP3,PCLAF,PLEK,PPM1E,PRC1,PSTPIP2,PTGER4,PXN,S100A10,S1PR1,SCIN,SPC25,SPTBN4,STMN1,TACC2,TMSB10,TRDN,TSPAN32,UHRF1,WDR62,WEE1,XIRP1,XRCC2"} {"GO.ID":"GO:0046643","Term":"regulation of gamma-delta T cell activation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2799,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NOD2"} {"GO.ID":"GO:1905165","Term":"regulation of lysosomal protein catabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2800,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ATP13A2"} {"GO.ID":"GO:0090306","Term":"meiotic spindle assembly","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2801,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NDC80"} {"GO.ID":"GO:0035627","Term":"ceramide transport","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2802,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ABCB1"} {"GO.ID":"GO:0010172","Term":"embryonic body morphogenesis","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2803,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"IFT122"} {"GO.ID":"GO:0048934","Term":"peripheral nervous system neuron differentiation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2804,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ONECUT2"} {"GO.ID":"GO:0048935","Term":"peripheral nervous system neuron development","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2805,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ONECUT2"} {"GO.ID":"GO:0160049","Term":"negative regulation of cGAS/STING signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2806,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"AURKB"} {"GO.ID":"GO:0009214","Term":"cyclic nucleotide catabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2807,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PDE4B"} {"GO.ID":"GO:0090161","Term":"Golgi ribbon formation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2808,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"OPTN"} {"GO.ID":"GO:0070486","Term":"leukocyte aggregation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2809,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NR4A3"} {"GO.ID":"GO:0034392","Term":"negative regulation of smooth muscle cell apoptotic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2810,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"EDN1"} {"GO.ID":"GO:0034350","Term":"regulation of glial cell apoptotic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2811,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DLL1"} {"GO.ID":"GO:0034375","Term":"high-density lipoprotein particle remodeling","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2812,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"LPL"} {"GO.ID":"GO:0070142","Term":"synaptic vesicle budding","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2813,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DNM1"} {"GO.ID":"GO:0034309","Term":"primary alcohol biosynthetic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2814,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DAB2"} {"GO.ID":"GO:0070254","Term":"mucus secretion","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2815,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"AGR2"} {"GO.ID":"GO:0072075","Term":"metanephric mesenchyme development","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2816,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"STAT1"} {"GO.ID":"GO:0003356","Term":"regulation of cilium beat frequency","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2817,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DNAAF1"} {"GO.ID":"GO:0032354","Term":"response to follicle-stimulating hormone","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2818,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"EDN1"} {"GO.ID":"GO:0034111","Term":"negative regulation of homotypic cell-cell adhesion","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2819,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CEACAM1"} {"GO.ID":"GO:0010663","Term":"positive regulation of striated muscle cell apoptotic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2820,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CAMK2D"} {"GO.ID":"GO:0010666","Term":"positive regulation of cardiac muscle cell apoptotic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2821,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CAMK2D"} {"GO.ID":"GO:1990166","Term":"protein localization to site of double-strand break","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2822,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PARP3"} {"GO.ID":"GO:1900119","Term":"positive regulation of execution phase of apoptosis","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2823,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ZC3H12A"} {"GO.ID":"GO:0071044","Term":"histone mRNA catabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2824,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"XRN1"} {"GO.ID":"GO:0090557","Term":"establishment of endothelial intestinal barrier","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2825,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"RAPGEF2"} {"GO.ID":"GO:0002357","Term":"defense response to tumor cell","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2826,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"KLF4"} {"GO.ID":"GO:0042451","Term":"purine nucleoside biosynthetic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2827,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PRTFDC1"} {"GO.ID":"GO:0042455","Term":"ribonucleoside biosynthetic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2828,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PRTFDC1"} {"GO.ID":"GO:0097084","Term":"vascular associated smooth muscle cell development","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2829,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"COMP"} {"GO.ID":"GO:0046068","Term":"cGMP metabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2830,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NPR1"} {"GO.ID":"GO:0042415","Term":"norepinephrine metabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2831,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"EPAS1"} {"GO.ID":"GO:0070561","Term":"vitamin D receptor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2832,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PIM1"} {"GO.ID":"GO:0090657","Term":"telomeric loop disassembly","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2833,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"RECQL4"} {"GO.ID":"GO:1902047","Term":"polyamine transmembrane transport","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2834,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ATP13A2"} {"GO.ID":"GO:0070572","Term":"positive regulation of neuron projection regeneration","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2835,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"SCARF1"} {"GO.ID":"GO:0042182","Term":"ketone catabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2836,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CBR3"} {"GO.ID":"GO:0002430","Term":"complement receptor mediated signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2837,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"C3"} {"GO.ID":"GO:0048385","Term":"regulation of retinoic acid receptor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2838,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DHRS3"} {"GO.ID":"GO:1900747","Term":"negative regulation of vascular endothelial growth factor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2839,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"IL12A"} {"GO.ID":"GO:0014819","Term":"regulation of skeletal muscle contraction","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2840,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"KCNJ2"} {"GO.ID":"GO:0051354","Term":"negative regulation of oxidoreductase activity","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2841,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"AOC3"} {"GO.ID":"GO:0071361","Term":"cellular response to ethanol","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2842,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CCL7"} {"GO.ID":"GO:0010917","Term":"negative regulation of mitochondrial membrane potential","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2843,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PMAIP1"} {"GO.ID":"GO:0010936","Term":"negative regulation of macrophage cytokine production","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2844,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NOD2"} {"GO.ID":"GO:0051469","Term":"vesicle fusion with vacuole","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2845,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CHMP4C"} {"GO.ID":"GO:0061469","Term":"regulation of type B pancreatic cell proliferation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2846,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NR4A3"} {"GO.ID":"GO:0038180","Term":"nerve growth factor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2847,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"RAPGEF2"} {"GO.ID":"GO:0072182","Term":"regulation of nephron tubule epithelial cell differentiation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2848,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"STAT1"} {"GO.ID":"GO:0042745","Term":"circadian sleep/wake cycle","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2849,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"GHRL"} {"GO.ID":"GO:0106070","Term":"regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2850,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PDE4B"} {"GO.ID":"GO:0072283","Term":"metanephric renal vesicle morphogenesis","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2851,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"STAT1"} {"GO.ID":"GO:0046462","Term":"monoacylglycerol metabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2852,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DGAT2"} {"GO.ID":"GO:0097152","Term":"mesenchymal cell apoptotic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2853,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"SYNE1"} {"GO.ID":"GO:0048755","Term":"branching morphogenesis of a nerve","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2854,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"LRRK2"} {"GO.ID":"GO:0007144","Term":"female meiosis I","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2855,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"NDC80"} {"GO.ID":"GO:1904753","Term":"negative regulation of vascular associated smooth muscle cell migration","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2856,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"MIR503"} {"GO.ID":"GO:0048712","Term":"negative regulation of astrocyte differentiation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2857,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DAB1"} {"GO.ID":"GO:0046129","Term":"purine ribonucleoside biosynthetic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2858,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PRTFDC1"} {"GO.ID":"GO:0061763","Term":"multivesicular body-lysosome fusion","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2859,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CHMP4C"} {"GO.ID":"GO:0036295","Term":"cellular response to increased oxygen levels","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2860,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"FAS"} {"GO.ID":"GO:1902259","Term":"regulation of delayed rectifier potassium channel activity","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2861,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"KCNE5"} {"GO.ID":"GO:1901142","Term":"insulin metabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2862,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CEACAM1"} {"GO.ID":"GO:0098885","Term":"modification of postsynaptic actin cytoskeleton","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2863,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CTTNBP2"} {"GO.ID":"GO:1903897","Term":"regulation of PERK-mediated unfolded protein response","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2864,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"AGR2"} {"GO.ID":"GO:0071871","Term":"response to epinephrine","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2865,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PDE4B"} {"GO.ID":"GO:0035235","Term":"ionotropic glutamate receptor signaling pathway","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2866,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"GRIN3A"} {"GO.ID":"GO:0051561","Term":"positive regulation of mitochondrial calcium ion concentration","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2867,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"TGM2"} {"GO.ID":"GO:0072672","Term":"neutrophil extravasation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2868,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ADAM8"} {"GO.ID":"GO:0061517","Term":"macrophage proliferation","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2869,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CSF1"} {"GO.ID":"GO:0048680","Term":"positive regulation of axon regeneration","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2870,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"SCARF1"} {"GO.ID":"GO:0006833","Term":"water transport","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2871,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"CTNS"} {"GO.ID":"GO:0045837","Term":"negative regulation of membrane potential","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2872,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"PMAIP1"} {"GO.ID":"GO:0006544","Term":"glycine metabolic process","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2873,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"DHFR"} {"GO.ID":"GO:0046618","Term":"xenobiotic export from cell","Annotated":11,"Significant":1,"Expected":0.66,"Rank in p.value_classic":2874,"p.value_elim":0.49527,"p.value_classic":0.49618,"genes":"ABCB1"} {"GO.ID":"GO:0045664","Term":"regulation of neuron differentiation","Annotated":143,"Significant":9,"Expected":8.64,"Rank in p.value_classic":2875,"p.value_elim":0.49565,"p.value_classic":0.49874,"genes":"B2M,BCL6,CASZ1,DAB1,DLL1,LRRK2,MMD,NRCAM,WDR62"} {"GO.ID":"GO:0022407","Term":"regulation of cell-cell adhesion","Annotated":401,"Significant":62,"Expected":24.22,"Rank in p.value_classic":85,"p.value_elim":0.49593,"p.value_classic":5.5e-12,"genes":"ADAM8,ASCL2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CEACAM1,CTLA4,CYLD,EPHB3,FGL1,FGL2,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL1RN,IL4I1,IL7,IRF1,JAK2,JAK3,KITLG,KLF4,KLRK1,LAG3,LYN,MDGA1,NOD2,NR4A3,PDCD1LG2,PTPRU,RIPK2,SLAMF1,SOCS1,TBX21,TNFRSF14,TNFRSF21,TNFSF13B,TSPAN32,VCAM1,ZC3H12A"} {"GO.ID":"GO:0006281","Term":"DNA repair","Annotated":573,"Significant":41,"Expected":34.61,"Rank in p.value_classic":1642,"p.value_elim":0.49634,"p.value_classic":0.14568,"genes":"BACH1,BRCA1,CDC45,CDCA5,CDK1,CHAF1B,CLSPN,DMC1,DTL,DTX3L,EEPD1,EME1,ESCO2,EXO1,FANCE,FBXO6,FEN1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,NEIL3,PARP10,PARP3,PARP9,PCLAF,PML,POLB,POLE2,RAD54B,RAD54L,RECQL4,RMI2,TICRR,TONSL,UBE2T,UHRF1,UNG,XRCC2"} {"GO.ID":"GO:0001704","Term":"formation of primary germ layer","Annotated":110,"Significant":7,"Expected":6.64,"Rank in p.value_classic":2876,"p.value_elim":0.49674,"p.value_classic":0.49945,"genes":"ITGA7,ITGB5,KLF4,LAMB3,MMP9,SOX17,TAL1"} {"GO.ID":"GO:0140056","Term":"organelle localization by membrane tethering","Annotated":77,"Significant":5,"Expected":4.65,"Rank in p.value_classic":2877,"p.value_elim":0.49803,"p.value_classic":0.5003,"genes":"PLEK,RALB,STX11,STX1A,SYT1"} {"GO.ID":"GO:0006509","Term":"membrane protein ectodomain proteolysis","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2878,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"ADAM8,P2RX7,TSPAN15"} {"GO.ID":"GO:0045682","Term":"regulation of epidermis development","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2879,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"DLL1,MAFF,PLAAT4"} {"GO.ID":"GO:0061097","Term":"regulation of protein tyrosine kinase activity","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2880,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"AGT,MVP,NCF1"} {"GO.ID":"GO:0042149","Term":"cellular response to glucose starvation","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2881,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"PMAIP1,SESN3,ZC3H12A"} {"GO.ID":"GO:0002639","Term":"positive regulation of immunoglobulin production","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2882,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"CD28,HLA-E,TBX21"} {"GO.ID":"GO:0046578","Term":"regulation of Ras protein signal transduction","Annotated":44,"Significant":3,"Expected":2.66,"Rank in p.value_classic":2883,"p.value_elim":0.49949,"p.value_classic":0.50121,"genes":"CSF1,KITLG,RASGRF1"} {"GO.ID":"GO:0007266","Term":"Rho protein signal transduction","Annotated":127,"Significant":8,"Expected":7.67,"Rank in p.value_classic":2884,"p.value_elim":0.50069,"p.value_classic":0.5036,"genes":"BCL6,CELSR1,F2RL3,LRRK2,MCF2L,NRP1,STMN1,TAGAP"} {"GO.ID":"GO:0090398","Term":"cellular senescence","Annotated":94,"Significant":6,"Expected":5.68,"Rank in p.value_classic":2885,"p.value_elim":0.50261,"p.value_classic":0.50512,"genes":"B2M,BCL6,COMP,GCH1,HLA-G,PML"} {"GO.ID":"GO:0000725","Term":"recombinational repair","Annotated":173,"Significant":17,"Expected":10.45,"Rank in p.value_classic":1002,"p.value_elim":0.50478,"p.value_classic":0.03248,"genes":"BRCA1,CDC45,DMC1,FEN1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RAD54B,RAD54L,RECQL4,RMI2,TONSL,UHRF1,XRCC2"} {"GO.ID":"GO:0009719","Term":"response to endogenous stimulus","Annotated":1333,"Significant":84,"Expected":80.51,"Rank in p.value_classic":2363,"p.value_elim":0.50491,"p.value_classic":0.35372,"genes":"ACOD1,ACSL1,AGT,APPL2,BCL2L11,BRCA1,C2,CASP4,CASP7,CASTOR1,CCL5,CCNA2,CD38,CDC6,CDH5,CEACAM1,CHRD,COMP,CRHBP,CTSL,CTSS,CX3CR1,DAB2,DLL1,DTNBP1,EDN1,EGR2,EME1,FAM107A,FSTL4,GAREM1,GHRL,GNG2,HGF,HTRA1,ICAM1,IL12A,IL1RN,ITGB5,JAK2,JAK3,KLF4,LBH,LPL,LRP5,LRRK2,LYN,MIR503,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,P2RX7,PADI2,PAQR8,PDE3B,PDK4,PID1,PML,PNPLA3,PTGER4,PTPRU,PXN,RAPGEF2,RIPK2,RXFP1,SESN3,SHCBP1,SLC12A3,SLC4A7,SOCS1,SSTR2,STAMBPL1,STAT1,STAT2,TGM2,TNFAIP6,TNFRSF11A,TNFSF10,TYMS,VCAM1,VEGFC,XRN1"} {"GO.ID":"GO:0045669","Term":"positive regulation of osteoblast differentiation","Annotated":61,"Significant":4,"Expected":3.68,"Rank in p.value_classic":2886,"p.value_elim":0.50529,"p.value_classic":0.50731,"genes":"HGF,IFITM1,LRP5,TMEM119"} {"GO.ID":"GO:1903036","Term":"positive regulation of response to wounding","Annotated":61,"Significant":4,"Expected":3.68,"Rank in p.value_classic":2887,"p.value_elim":0.50529,"p.value_classic":0.50731,"genes":"ENPP4,HBEGF,SCARF1,THBD"} {"GO.ID":"GO:0043266","Term":"regulation of potassium ion transport","Annotated":61,"Significant":4,"Expected":3.68,"Rank in p.value_classic":2888,"p.value_elim":0.50529,"p.value_classic":0.50731,"genes":"ANK2,ATP1B2,KCNE5,KCNJ2"} {"GO.ID":"GO:0032922","Term":"circadian regulation of gene expression","Annotated":61,"Significant":4,"Expected":3.68,"Rank in p.value_classic":2889,"p.value_elim":0.50529,"p.value_classic":0.50731,"genes":"BHLHE41,BMAL2,PML,RELB"} {"GO.ID":"GO:0045806","Term":"negative regulation of endocytosis","Annotated":61,"Significant":4,"Expected":3.68,"Rank in p.value_classic":2890,"p.value_elim":0.50529,"p.value_classic":0.50731,"genes":"CD300LF,DYSF,NECAB2,PLSCR1"} {"GO.ID":"GO:0016125","Term":"sterol metabolic process","Annotated":111,"Significant":7,"Expected":6.7,"Rank in p.value_classic":2891,"p.value_elim":0.50642,"p.value_classic":0.50914,"genes":"APOL1,APOL2,FAXDC2,LRP5,SCARF1,SOAT1,TTC39B"} {"GO.ID":"GO:0006812","Term":"monoatomic cation transport","Annotated":717,"Significant":52,"Expected":43.3,"Rank in p.value_classic":1375,"p.value_elim":0.50768,"p.value_classic":0.09545,"genes":"ANK2,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,B2M,CACNA2D3,CALHM6,CAMK2D,CCL5,CCL8,CTNS,CTSS,CXCL10,CXCL11,CXCL9,CYSLTR1,EDN1,F2RL3,FLVCR2,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LMTK2,LYN,MCOLN2,MMP9,P2RX4,P2RX7,PDE4B,PKD1L3,PLPP4,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SPTBN4,SRI,STEAP4,TESC,TMEM109,TPCN1,TRDN"} {"GO.ID":"GO:0003018","Term":"vascular process in circulatory system","Annotated":211,"Significant":13,"Expected":12.74,"Rank in p.value_classic":2907,"p.value_elim":0.50792,"p.value_classic":0.51167,"genes":"ABCB1,ABCG2,AGT,ATP1B2,CD38,CDH5,CEACAM1,COMP,CYSLTR1,EDN1,GCH1,HRH2,NPR1"} {"GO.ID":"GO:1901293","Term":"nucleoside phosphate biosynthetic process","Annotated":261,"Significant":16,"Expected":15.76,"Rank in p.value_classic":2908,"p.value_elim":0.50855,"p.value_classic":0.51273,"genes":"ACSL1,AK1,CMPK2,IDO1,IDO2,KARS1,NPR1,PARP10,PARP9,PDK4,PID1,RRM2,SLC4A7,TK1,TYMS,VPS9D1"} {"GO.ID":"GO:0034067","Term":"protein localization to Golgi apparatus","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2892,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"GBP5,OPTN"} {"GO.ID":"GO:0006654","Term":"phosphatidic acid biosynthetic process","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2893,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"LCLAT1,PNPLA3"} {"GO.ID":"GO:0099171","Term":"presynaptic modulation of chemical synaptic transmission","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2894,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"ADORA3,GRIN3A"} {"GO.ID":"GO:0002068","Term":"glandular epithelial cell development","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2895,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"DLL1,SIDT2"} {"GO.ID":"GO:0034381","Term":"plasma lipoprotein particle clearance","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2896,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"DGAT2,SOAT1"} {"GO.ID":"GO:0010830","Term":"regulation of myotube differentiation","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2897,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"BHLHE41,TMEM119"} {"GO.ID":"GO:0060544","Term":"regulation of necroptotic process","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2898,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"CYLD,ZBP1"} {"GO.ID":"GO:0015012","Term":"heparan sulfate proteoglycan biosynthetic process","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2899,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"DSE,XYLT1"} {"GO.ID":"GO:0050654","Term":"chondroitin sulfate proteoglycan metabolic process","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2900,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"DSE,XYLT1"} {"GO.ID":"GO:1901021","Term":"positive regulation of calcium ion transmembrane transporter activity","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2901,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"ANK2,TRDN"} {"GO.ID":"GO:0032232","Term":"negative regulation of actin filament bundle assembly","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2902,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"S1PR1,STMN1"} {"GO.ID":"GO:0019076","Term":"viral release from host cell","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2903,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"CHMP4C,TRIM31"} {"GO.ID":"GO:1904738","Term":"vascular associated smooth muscle cell migration","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2904,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"MIR503,NR4A3"} {"GO.ID":"GO:0045761","Term":"regulation of adenylate cyclase activity","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2905,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0035891","Term":"exit from host cell","Annotated":28,"Significant":2,"Expected":1.69,"Rank in p.value_classic":2906,"p.value_elim":0.50952,"p.value_classic":0.51091,"genes":"CHMP4C,TRIM31"} {"GO.ID":"GO:0048731","Term":"system development","Annotated":3110,"Significant":201,"Expected":187.83,"Rank in p.value_classic":1567,"p.value_elim":0.50957,"p.value_classic":0.13764,"genes":"AATK,ACOD1,ADAM8,AGR2,AGT,AIM2,AMER1,AMOT,ANK2,ANKH,ANTXR1,APPL2,ASB2,ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BCL2L11,BCL6,BHLHE41,BRCA1,C21orf91,C3,C3orf70,CASP7,CASZ1,CD274,CD28,CD38,CD40,CDH5,CDK1,CDKN2C,CEACAM1,CELSR1,CENPF,CHAC1,CHRD,COL9A2,COLQ,COMP,CSF1,CTNS,CX3CR1,CXADR,CXCL10,CXCR3,CYP1A1,CYSLTR1,DAB1,DAB2,DHFR,DHRS3,DLL1,DMC1,DNAAF1,DTNBP1,DYNLT1,E2F1,E2F2,E2F8,EDA,EDN1,EGR2,EPAS1,EPHB3,EPOP,EXO1,FGL1,FSTL4,GABRA3,GCNT3,GFRA2,GHRL,GLDN,GLUL,GPR183,GRIN3A,HAPLN3,HELLS,HESX1,HGF,HLA-B,HLA-E,HLA-G,HSD11B1,IDO1,IFT122,IGF2R,IL12A,IL15,IL15RA,INA,JAK2,KCNJ10,KIF26A,KITLG,KLF4,KREMEN1,LGI2,LIMK2,LRP5,LRRK2,LTA,LYN,MAF,MARCKSL1,MDGA1,MERTK,MICAL2,MIR503,MMD,MMP9,MTSS1,NPR1,NRCAM,NRGN,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,OVOL1,P2RX4,P2RX7,PADI2,PARP3,PCDH12,PCDHGC3,PDCD1,PDE3B,PIM1,PKD1L3,PLAAT3,PLCD3,PLXNA2,PML,POLB,PRKX,PROK2,PTGER4,RAPGEF2,RASGRF1,RHOBTB3,RNF213,RTN4RL1,RXFP1,S100A10,S1PR1,SAT1,SCARF1,SCIN,SCO2,SDC2,SELENOP,SEMA6B,SEPTIN4,SERINC5,SGPL1,SIDT2,SLC45A3,SLC4A7,SNX10,SOX17,SPTBN4,SRI,SSBP3,SSTR2,STAP1,STAT1,STMN1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TBX21,TGM2,THBS2,TIFAB,TMEM119,TNFAIP2,TNFAIP6,TNFRSF11A,TNFRSF21,TNFSF10,TYMP,TYMS,TYRO3,UNG,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,WWP1,XRCC2,XYLT1,ZC3H12A"} {"GO.ID":"GO:0060348","Term":"bone development","Annotated":178,"Significant":11,"Expected":10.75,"Rank in p.value_classic":2909,"p.value_elim":0.51,"p.value_classic":0.51345,"genes":"AMER1,COMP,DHRS3,GHRL,LRP5,PTGER4,SNX10,TGM2,TIFAB,TMEM119,XYLT1"} {"GO.ID":"GO:0035270","Term":"endocrine system development","Annotated":95,"Significant":6,"Expected":5.74,"Rank in p.value_classic":2910,"p.value_elim":0.51306,"p.value_classic":0.51557,"genes":"CTNS,DLL1,EDN1,HESX1,ONECUT2,SIDT2"} {"GO.ID":"GO:1904062","Term":"regulation of monoatomic cation transmembrane transport","Annotated":213,"Significant":22,"Expected":12.86,"Rank in p.value_classic":745,"p.value_elim":0.51316,"p.value_classic":0.0097,"genes":"ANK2,ATP1B2,CAMK2D,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ2,LYN,MMP9,P2RX4,P2RX7,PDE4B,PML,SCN4B,SLC31A2,SRI,TESC,TRDN"} {"GO.ID":"GO:0030595","Term":"leukocyte chemotaxis","Annotated":192,"Significant":33,"Expected":11.6,"Rank in p.value_classic":168,"p.value_elim":0.51341,"p.value_classic":4.3e-08,"genes":"ADAM8,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CSF1,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,GPR183,HSD3B7,IL12A,KLRK1,LYN,MTUS1,NOD2,PADI2,PDE4B,S1PR1,SLAMF1,SLAMF8,STAP1,TNFAIP6,TNFRSF11A,VEGFC"} {"GO.ID":"GO:0010171","Term":"body morphogenesis","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2911,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"IFT122,SGPL1,SSBP3"} {"GO.ID":"GO:0010824","Term":"regulation of centrosome duplication","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2912,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"BRCA1,CCNF,CHMP4C"} {"GO.ID":"GO:0048013","Term":"ephrin receptor signaling pathway","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2913,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"EPHB3,LYN,MMP9"} {"GO.ID":"GO:0030520","Term":"intracellular estrogen receptor signaling pathway","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2914,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"BRCA1,LBH,PADI2"} {"GO.ID":"GO:0032371","Term":"regulation of sterol transport","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2915,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"EEPD1,OSBPL6,TTC39B"} {"GO.ID":"GO:0032374","Term":"regulation of cholesterol transport","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2916,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"EEPD1,OSBPL6,TTC39B"} {"GO.ID":"GO:0019933","Term":"cAMP-mediated signaling","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2917,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"PDE3B,PDE4B,RAPGEF2"} {"GO.ID":"GO:0060688","Term":"regulation of morphogenesis of a branching structure","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2918,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"AGT,HGF,LRRK2"} {"GO.ID":"GO:0055021","Term":"regulation of cardiac muscle tissue growth","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2919,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"CDK1,EDN1,PIM1"} {"GO.ID":"GO:1904262","Term":"negative regulation of TORC1 signaling","Annotated":45,"Significant":3,"Expected":2.72,"Rank in p.value_classic":2920,"p.value_elim":0.51473,"p.value_classic":0.51647,"genes":"CASTOR1,DEPTOR,SESN3"} {"GO.ID":"GO:0071345","Term":"cellular response to cytokine stimulus","Annotated":704,"Significant":103,"Expected":42.52,"Rank in p.value_classic":33,"p.value_elim":0.51496,"p.value_classic":1.3e-17,"genes":"ACOD1,ACSL1,AIM2,APPL2,BRCA1,CARD16,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCRL2,CD300LF,CD40,CD74,CEACAM1,CRHBP,CSF1,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,EDN1,FAS,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,HELLS,HLA-DPA1,ICAM1,IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL31RA,IL3RA,IL7,INA,IRF1,IRF7,JAK2,JAK3,KLF4,LILRA1,LILRA2,LYN,MCM2,MRAS,MT2A,MYBL2,NLRC5,NLRP12,OAS2,OAS3,OSM,PADI2,PARP14,PARP9,PID1,PML,PYHIN1,RAB20,RIPK2,RUFY4,SBNO2,SNX10,SOCS1,SOX17,STAP1,STAT1,STAT2,TANK,TICAM2,TIFA,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,VCAM1,VEGFC,VRK2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0099536","Term":"synaptic signaling","Annotated":566,"Significant":38,"Expected":34.18,"Rank in p.value_classic":2107,"p.value_elim":0.51572,"p.value_classic":0.26972,"genes":"ADORA3,AKAP7,ASIC1,CADPS2,CD38,COLQ,CRHBP,CX3CR1,DLGAP3,DNM1,DTNBP1,DYSF,EDN1,EGR2,ERC2,FAM107A,GABRA3,GHRL,GRIN3A,GRM8,HRH2,INA,INSYN2A,JAK2,KCNJ10,LRRK2,MCTP2,MYOF,P2RX4,P2RX7,PRRT2,RAPGEF2,RASGRF1,STX11,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0001101","Term":"response to acid chemical","Annotated":112,"Significant":7,"Expected":6.76,"Rank in p.value_classic":2921,"p.value_elim":0.51603,"p.value_classic":0.51875,"genes":"CASTOR1,EDN1,LYN,PNPLA3,SESN3,SOCS1,STAMBPL1"} {"GO.ID":"GO:0051592","Term":"response to calcium ion","Annotated":112,"Significant":7,"Expected":6.76,"Rank in p.value_classic":2922,"p.value_elim":0.51603,"p.value_classic":0.51875,"genes":"CAMK2D,CRHBP,EDN1,P2RX7,SUCNR1,SYT1,SYT6"} {"GO.ID":"GO:0045936","Term":"negative regulation of phosphate metabolic process","Annotated":329,"Significant":20,"Expected":19.87,"Rank in p.value_classic":2925,"p.value_elim":0.51686,"p.value_classic":0.52155,"genes":"AGT,CDKN2C,CEACAM1,DEPTOR,DTNBP1,HGF,LRP5,LRRK2,LYN,MVP,NLRP12,PARP14,PID1,PKIB,PLEK,PPM1E,SOCS1,STAP1,WARS1,ZC3H12A"} {"GO.ID":"GO:0070301","Term":"cellular response to hydrogen peroxide","Annotated":62,"Significant":4,"Expected":3.74,"Rank in p.value_classic":2923,"p.value_elim":0.51822,"p.value_classic":0.52025,"genes":"CDK1,EDN1,IL18BP,KLF4"} {"GO.ID":"GO:1904356","Term":"regulation of telomere maintenance via telomere lengthening","Annotated":62,"Significant":4,"Expected":3.74,"Rank in p.value_classic":2924,"p.value_elim":0.51822,"p.value_classic":0.52025,"genes":"AURKB,GCH1,PKIB,XRN1"} {"GO.ID":"GO:0016042","Term":"lipid catabolic process","Annotated":246,"Significant":15,"Expected":14.86,"Rank in p.value_classic":2926,"p.value_elim":0.51919,"p.value_classic":0.52324,"genes":"ENPP2,HCAR2,HSD11B1,LPL,NAAA,PDE3B,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PNPLA3,SCARF1,SGPL1"} {"GO.ID":"GO:0012501","Term":"programmed cell death","Annotated":1650,"Significant":133,"Expected":99.65,"Rank in p.value_classic":396,"p.value_elim":0.51944,"p.value_classic":0.00023,"genes":"ADAM8,AGT,AIFM2,AIM2,ATF3,ATF5,ATP13A2,AURKB,BCL2A1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BUB1B,C3orf38,CAMK2D,CARD16,CASP4,CASP7,CCL5,CD274,CD28,CD38,CD40,CD74,CDCA7,CDH5,CDK1,CHAC1,COMP,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCR3,CYLD,DAB2,DEPTOR,DLL1,DRAM1,E2F1,E2F2,EBF4,EDN1,FAS,G0S2,GADD45B,GBP1,GBP2,GBP3,GBP5,GCH1,GHRL,GIMAP8,GRAMD4,GSDMA,GSDMD,HCAR2,HELLS,HGF,HLA-G,HTRA1,ICAM1,IDO1,IFI27,IFIT2,IFIT3,IGF2R,IL12A,IL31RA,IL7,IRF1,IRF7,JAK2,JAK3,KITLG,KLF4,KREMEN1,LAMP3,LRP5,LRRK2,LTA,LYN,MAD2L1,MCM2,MEFV,MERTK,MMP9,MUC1,MYBL2,NLRP12,NOD2,NRP1,P2RX4,P2RX7,PCDHGC3,PDCD1,PDK4,PIM1,PLSCR1,PMAIP1,PML,POLB,PROK2,RALB,RAPGEF2,RIPK2,SCIN,SEPTIN4,SGPL1,STAT1,SYNE1,TGM2,TIFAB,TMEM109,TNFAIP8L3,TNFRSF21,TNFSF10,TNFSF18,TOP2A,TRIM69,TYRO3,UBD,UNG,USP53,XAF1,XKR6,XRCC2,ZBP1,ZC3H12A"} {"GO.ID":"GO:0009411","Term":"response to UV","Annotated":146,"Significant":9,"Expected":8.82,"Rank in p.value_classic":2930,"p.value_elim":0.52101,"p.value_classic":0.52412,"genes":"AURKB,CASP7,CDC25A,DTL,FEN1,IL12A,MMP9,PCLAF,PML"} {"GO.ID":"GO:0062014","Term":"negative regulation of small molecule metabolic process","Annotated":79,"Significant":5,"Expected":4.77,"Rank in p.value_classic":2927,"p.value_elim":0.52101,"p.value_classic":0.5233,"genes":"APPL2,BRCA1,CEACAM1,PID1,PLEK"} {"GO.ID":"GO:1904035","Term":"regulation of epithelial cell apoptotic process","Annotated":79,"Significant":5,"Expected":4.77,"Rank in p.value_classic":2928,"p.value_elim":0.52101,"p.value_classic":0.5233,"genes":"CD40,CDH5,HLA-G,ICAM1,JAK2"} {"GO.ID":"GO:0010951","Term":"negative regulation of endopeptidase activity","Annotated":79,"Significant":5,"Expected":4.77,"Rank in p.value_classic":2929,"p.value_elim":0.52101,"p.value_classic":0.5233,"genes":"CARD16,KLF4,LAMP3,MMP9,SERPING1"} {"GO.ID":"GO:0010563","Term":"negative regulation of phosphorus metabolic process","Annotated":330,"Significant":20,"Expected":19.93,"Rank in p.value_classic":2992,"p.value_elim":0.52248,"p.value_classic":0.52718,"genes":"AGT,CDKN2C,CEACAM1,DEPTOR,DTNBP1,HGF,LRP5,LRRK2,LYN,MVP,NLRP12,PARP14,PID1,PKIB,PLEK,PPM1E,SOCS1,STAP1,WARS1,ZC3H12A"} {"GO.ID":"GO:0043687","Term":"post-translational protein modification","Annotated":880,"Significant":53,"Expected":53.15,"Rank in p.value_classic":3017,"p.value_elim":0.52263,"p.value_classic":0.53046,"genes":"AMER1,ASB2,AURKB,BRCA1,CCNA2,CCNF,CDCA3,CISH,CYLD,DSCC1,DTL,DTX3L,EGR2,EPAS1,ESCO2,FAM107A,FBXO6,FEM1C,IFI27,IFIH1,JADE2,JAK2,LRRK2,MAD2L1,MEFV,NMI,NOD2,NUB1,OTUD1,PARP10,PARP12,PARP14,PARP3,PML,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SOCS1,STAMBPL1,STX1A,TANK,TRIM17,TRIM22,TRIM31,TRIM69,UBD,UBE2L6,UBE2T,UHRF1,WWP1,ZC3H12A"} {"GO.ID":"GO:0038202","Term":"TORC1 signaling","Annotated":96,"Significant":6,"Expected":5.8,"Rank in p.value_classic":2931,"p.value_elim":0.52342,"p.value_classic":0.52594,"genes":"CASTOR1,CTNS,DEPTOR,PIM1,SESN3,STAMBPL1"} {"GO.ID":"GO:0010934","Term":"macrophage cytokine production","Annotated":36,"Significant":7,"Expected":2.17,"Rank in p.value_classic":659,"p.value_elim":0.52359,"p.value_classic":0.00511,"genes":"CD74,HLA-G,LITAF,NOD2,P2RX7,RIPK2,TLR7"} {"GO.ID":"GO:0010935","Term":"regulation of macrophage cytokine production","Annotated":36,"Significant":7,"Expected":2.17,"Rank in p.value_classic":660,"p.value_elim":0.52359,"p.value_classic":0.00511,"genes":"CD74,HLA-G,LITAF,NOD2,P2RX7,RIPK2,TLR7"} {"GO.ID":"GO:2000515","Term":"negative regulation of CD4-positive, alpha-beta T cell activation","Annotated":27,"Significant":6,"Expected":1.63,"Rank in p.value_classic":655,"p.value_elim":0.52381,"p.value_classic":0.00472,"genes":"ASCL2,BCL6,CD274,JAK3,TBX21,ZC3H12A"} {"GO.ID":"GO:0042592","Term":"homeostatic process","Annotated":1318,"Significant":106,"Expected":79.6,"Rank in p.value_classic":502,"p.value_elim":0.52556,"p.value_classic":0.00116,"genes":"ACSL1,ADAM8,AGT,AIM2,ALAS1,ANK2,ANKH,APPL2,ATP13A2,ATP1B2,ATP6V0D2,B2M,BCL2L11,BCL6,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD38,CD40,CD74,CDH5,COMP,CSF1,CTNS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL9,CYLD,DGAT2,DLL1,EDN1,EPAS1,ERC2,F2RL3,FAM20A,FAS,G0S2,G6PC1,GHRL,GPR183,GRAMD1B,HCAR2,HLA-DRB1,ICAM1,IL15,IL31RA,IL7,IRF4,JAK2,JAK3,KCNJ10,KCNJ2,KITLG,LPL,LRP5,LRRK2,LYN,MERTK,MT2A,NCAPG2,NCF1,NOD2,NPR1,NR4A3,OCA2,P2RX4,P2RX7,PDE4B,PDK4,PIWIL4,PMAIP1,PML,PNPLA3,POLB,RAB20,S1PR1,SCO2,SEPTIN4,SESN3,SIDT2,SIT1,SLAMF8,SLC11A1,SLC12A3,SLC31A2,SLC4A7,SNX10,SOAT1,SRI,STAT1,STEAP4,SUCNR1,SV2B,TAL1,TGM2,TMEM119,TNFRSF11A,TNFSF13B,TRDN,TTC39B,TYRO3"} {"GO.ID":"GO:0043401","Term":"steroid hormone mediated signaling pathway","Annotated":113,"Significant":7,"Expected":6.82,"Rank in p.value_classic":2993,"p.value_elim":0.52557,"p.value_classic":0.5283,"genes":"BRCA1,DAB2,JAK2,LBH,NR4A3,PADI2,PAQR8"} {"GO.ID":"GO:0015697","Term":"quaternary ammonium group transport","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2932,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SLC6A12"} {"GO.ID":"GO:0001991","Term":"regulation of systemic arterial blood pressure by circulatory renin-angiotensin","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2933,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SUCNR1"} {"GO.ID":"GO:1901526","Term":"positive regulation of mitophagy","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2934,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"NOD2"} {"GO.ID":"GO:0030431","Term":"sleep","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2935,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"GHRL"} {"GO.ID":"GO:0090336","Term":"positive regulation of brown fat cell differentiation","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2936,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PIM1"} {"GO.ID":"GO:0009158","Term":"ribonucleoside monophosphate catabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2937,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DPYS"} {"GO.ID":"GO:0099188","Term":"postsynaptic cytoskeleton organization","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2938,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"INA"} {"GO.ID":"GO:0030277","Term":"maintenance of gastrointestinal epithelium","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2939,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"NOD2"} {"GO.ID":"GO:0030214","Term":"hyaluronan catabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2940,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"LYVE1"} {"GO.ID":"GO:0090136","Term":"epithelial cell-cell adhesion","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2941,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"ITGB5"} {"GO.ID":"GO:0010766","Term":"negative regulation of sodium ion transport","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2942,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"CAMK2D"} {"GO.ID":"GO:0034393","Term":"positive regulation of smooth muscle cell apoptotic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2943,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"IL12A"} {"GO.ID":"GO:0002076","Term":"osteoblast development","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2944,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"LRP5"} {"GO.ID":"GO:0070141","Term":"response to UV-A","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2945,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"MMP9"} {"GO.ID":"GO:1900373","Term":"positive regulation of purine nucleotide biosynthetic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2946,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PID1"} {"GO.ID":"GO:0010889","Term":"regulation of sequestering of triglyceride","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2947,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"LPL"} {"GO.ID":"GO:0030810","Term":"positive regulation of nucleotide biosynthetic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2948,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PID1"} {"GO.ID":"GO:0030836","Term":"positive regulation of actin filament depolymerization","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2949,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PLEK"} {"GO.ID":"GO:0038083","Term":"peptidyl-tyrosine autophosphorylation","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2950,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"AATK"} {"GO.ID":"GO:0060766","Term":"negative regulation of androgen receptor signaling pathway","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2951,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DAB2"} {"GO.ID":"GO:1905668","Term":"positive regulation of protein localization to endosome","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2952,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DTX3L"} {"GO.ID":"GO:0003376","Term":"sphingosine-1-phosphate receptor signaling pathway","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2953,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"S1PR1"} {"GO.ID":"GO:0009650","Term":"UV protection","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2954,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"FEN1"} {"GO.ID":"GO:0060856","Term":"establishment of blood-brain barrier","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2955,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"LRP5"} {"GO.ID":"GO:0010635","Term":"regulation of mitochondrial fusion","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2956,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PID1"} {"GO.ID":"GO:0043174","Term":"nucleoside salvage","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2957,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PRTFDC1"} {"GO.ID":"GO:0043129","Term":"surfactant homeostasis","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2958,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"EPAS1"} {"GO.ID":"GO:0140896","Term":"cGAS/STING signaling pathway","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2959,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"AURKB"} {"GO.ID":"GO:0060576","Term":"intestinal epithelial cell development","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2960,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"TYMS"} {"GO.ID":"GO:0050655","Term":"dermatan sulfate proteoglycan metabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2961,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DSE"} {"GO.ID":"GO:0014857","Term":"regulation of skeletal muscle cell proliferation","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2962,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"JAK2"} {"GO.ID":"GO:0071394","Term":"cellular response to testosterone stimulus","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2963,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"NCF1"} {"GO.ID":"GO:0042276","Term":"error-prone translesion synthesis","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2964,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"POLE2"} {"GO.ID":"GO:0071340","Term":"skeletal muscle acetylcholine-gated channel clustering","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2965,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"COLQ"} {"GO.ID":"GO:0018158","Term":"protein oxidation","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2966,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"TRABD2A"} {"GO.ID":"GO:0140627","Term":"ubiquitin-dependent protein catabolic process via the C-end degron rule pathway","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2967,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"FEM1C"} {"GO.ID":"GO:0042762","Term":"regulation of sulfur metabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2968,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PDK4"} {"GO.ID":"GO:0061430","Term":"bone trabecula morphogenesis","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2969,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SBNO2"} {"GO.ID":"GO:0032700","Term":"negative regulation of interleukin-17 production","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2970,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"IL12A"} {"GO.ID":"GO:0046321","Term":"positive regulation of fatty acid oxidation","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2971,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"NR4A3"} {"GO.ID":"GO:1903427","Term":"negative regulation of reactive oxygen species biosynthetic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2972,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"CTNS"} {"GO.ID":"GO:0106049","Term":"regulation of cellular response to osmotic stress","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2973,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"TIFAB"} {"GO.ID":"GO:0051290","Term":"protein heterotetramerization","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2974,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"RRM2"} {"GO.ID":"GO:0007130","Term":"synaptonemal complex assembly","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2975,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"HORMAD1"} {"GO.ID":"GO:0045472","Term":"response to ether","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2976,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"ZC3H12A"} {"GO.ID":"GO:0097202","Term":"activation of cysteine-type endopeptidase activity","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2977,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"RIPK2"} {"GO.ID":"GO:0021670","Term":"lateral ventricle development","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2978,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"ATP1B2"} {"GO.ID":"GO:0098814","Term":"spontaneous synaptic transmission","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2979,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SYT1"} {"GO.ID":"GO:0048548","Term":"regulation of pinocytosis","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2980,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"APPL2"} {"GO.ID":"GO:1903826","Term":"L-arginine transmembrane transport","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2981,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SLC11A1"} {"GO.ID":"GO:0071801","Term":"regulation of podosome assembly","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2982,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"FSCN1"} {"GO.ID":"GO:0090030","Term":"regulation of steroid hormone biosynthetic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2983,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DAB2"} {"GO.ID":"GO:0048643","Term":"positive regulation of skeletal muscle tissue development","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2984,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"DLL1"} {"GO.ID":"GO:0006883","Term":"intracellular sodium ion homeostasis","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2985,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"ATP1B2"} {"GO.ID":"GO:0071679","Term":"commissural neuron axon guidance","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2986,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"NRP1"} {"GO.ID":"GO:0097576","Term":"vacuole fusion","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2987,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"CHMP4C"} {"GO.ID":"GO:0030397","Term":"membrane disassembly","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2988,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"PLAAT3"} {"GO.ID":"GO:0010310","Term":"regulation of hydrogen peroxide metabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2989,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"CTNS"} {"GO.ID":"GO:0006563","Term":"L-serine metabolic process","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2990,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"SERINC5"} {"GO.ID":"GO:0035589","Term":"G protein-coupled purinergic nucleotide receptor signaling pathway","Annotated":12,"Significant":1,"Expected":0.72,"Rank in p.value_classic":2991,"p.value_elim":0.52571,"p.value_classic":0.52663,"genes":"P2RY14"} {"GO.ID":"GO:0045648","Term":"positive regulation of erythrocyte differentiation","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":2995,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"STAT1,TAL1"} {"GO.ID":"GO:0051955","Term":"regulation of amino acid transport","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":2996,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"DTNBP1,P2RX7"} {"GO.ID":"GO:0051938","Term":"L-glutamate import","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":2997,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"DTNBP1,KCNJ10"} {"GO.ID":"GO:0070306","Term":"lens fiber cell differentiation","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":2998,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"MAF,PLAAT3"} {"GO.ID":"GO:0090183","Term":"regulation of kidney development","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":2999,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"AGT,STAT1"} {"GO.ID":"GO:0090140","Term":"regulation of mitochondrial fission","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3000,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"LRRK2,STAT2"} {"GO.ID":"GO:0010874","Term":"regulation of cholesterol efflux","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3001,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"EEPD1,TTC39B"} {"GO.ID":"GO:0045981","Term":"positive regulation of nucleotide metabolic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3002,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"P2RX7,PID1"} {"GO.ID":"GO:0010574","Term":"regulation of vascular endothelial growth factor production","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3003,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"BRCA1,C3"} {"GO.ID":"GO:1903055","Term":"positive regulation of extracellular matrix organization","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3004,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"AGT,FSCN1"} {"GO.ID":"GO:0150117","Term":"positive regulation of cell-substrate junction organization","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3005,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"NRP1,S100A10"} {"GO.ID":"GO:1900101","Term":"regulation of endoplasmic reticulum unfolded protein response","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3006,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"AGR2,BCL2L11"} {"GO.ID":"GO:0070528","Term":"protein kinase C signaling","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3007,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"CD40,PLEK"} {"GO.ID":"GO:0032768","Term":"regulation of monooxygenase activity","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3008,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"DHFR,GCH1"} {"GO.ID":"GO:2000279","Term":"negative regulation of DNA biosynthetic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3009,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"PARP3,XRN1"} {"GO.ID":"GO:0042743","Term":"hydrogen peroxide metabolic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3010,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"CTNS,CYP1A1"} {"GO.ID":"GO:1900544","Term":"positive regulation of purine nucleotide metabolic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3011,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"P2RX7,PID1"} {"GO.ID":"GO:0046473","Term":"phosphatidic acid metabolic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3012,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"LCLAT1,PNPLA3"} {"GO.ID":"GO:0050931","Term":"pigment cell differentiation","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3013,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"KITLG,OCA2"} {"GO.ID":"GO:0001569","Term":"branching involved in blood vessel morphogenesis","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3014,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"EDN1,NRP1"} {"GO.ID":"GO:0048512","Term":"circadian behavior","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3015,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"C3orf70,GHRL"} {"GO.ID":"GO:0052652","Term":"cyclic purine nucleotide metabolic process","Annotated":29,"Significant":2,"Expected":1.75,"Rank in p.value_classic":3016,"p.value_elim":0.52853,"p.value_classic":0.52993,"genes":"NPR1,PDE4B"} {"GO.ID":"GO:0170038","Term":"proteinogenic amino acid biosynthetic process","Annotated":46,"Significant":3,"Expected":2.78,"Rank in p.value_classic":3018,"p.value_elim":0.52972,"p.value_classic":0.53147,"genes":"DHFR,GLUL,SERINC5"} {"GO.ID":"GO:0030514","Term":"negative regulation of BMP signaling pathway","Annotated":46,"Significant":3,"Expected":2.78,"Rank in p.value_classic":3019,"p.value_elim":0.52972,"p.value_classic":0.53147,"genes":"CHRD,HTRA1,TNFAIP6"} {"GO.ID":"GO:1902116","Term":"negative regulation of organelle assembly","Annotated":46,"Significant":3,"Expected":2.78,"Rank in p.value_classic":3020,"p.value_elim":0.52972,"p.value_classic":0.53147,"genes":"BRCA1,LIMK2,LRRK2"} {"GO.ID":"GO:0015800","Term":"acidic amino acid transport","Annotated":46,"Significant":3,"Expected":2.78,"Rank in p.value_classic":3021,"p.value_elim":0.52972,"p.value_classic":0.53147,"genes":"DTNBP1,KCNJ10,P2RX7"} {"GO.ID":"GO:0042475","Term":"odontogenesis of dentin-containing tooth","Annotated":63,"Significant":4,"Expected":3.8,"Rank in p.value_classic":3022,"p.value_elim":0.531,"p.value_classic":0.53303,"genes":"BCL2L11,CSF1,EDA,FAM20A"} {"GO.ID":"GO:0033555","Term":"multicellular organismal response to stress","Annotated":63,"Significant":4,"Expected":3.8,"Rank in p.value_classic":3023,"p.value_elim":0.531,"p.value_classic":0.53303,"genes":"ASIC1,GCH1,IDO1,P2RX4"} {"GO.ID":"GO:0050878","Term":"regulation of body fluid levels","Annotated":274,"Significant":22,"Expected":16.55,"Rank in p.value_classic":1421,"p.value_elim":0.53219,"p.value_classic":0.10533,"genes":"AGR2,CD40,CEACAM1,COMP,CTNS,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,JAK2,LYN,MERTK,NPR1,OAS2,PLEK,PLSCR1,SERPING1,THBD,TIFAB,TSPAN32,TYRO3"} {"GO.ID":"GO:0060349","Term":"bone morphogenesis","Annotated":80,"Significant":5,"Expected":4.83,"Rank in p.value_classic":3024,"p.value_elim":0.53234,"p.value_classic":0.53463,"genes":"COMP,DHRS3,LRP5,TIFAB,TMEM119"} {"GO.ID":"GO:0070167","Term":"regulation of biomineral tissue development","Annotated":80,"Significant":5,"Expected":4.83,"Rank in p.value_classic":3025,"p.value_elim":0.53234,"p.value_classic":0.53463,"genes":"ANKH,COMP,P2RX7,S1PR1,TMEM119"} {"GO.ID":"GO:0071229","Term":"cellular response to acid chemical","Annotated":80,"Significant":5,"Expected":4.83,"Rank in p.value_classic":3026,"p.value_elim":0.53234,"p.value_classic":0.53463,"genes":"CASTOR1,PNPLA3,SESN3,SOCS1,STAMBPL1"} {"GO.ID":"GO:0060322","Term":"head development","Annotated":616,"Significant":37,"Expected":37.2,"Rank in p.value_classic":3028,"p.value_elim":0.533,"p.value_classic":0.53946,"genes":"AATK,AIM2,ATF5,ATP1B2,B2M,C21orf91,CENPF,CTNS,CX3CR1,DAB1,DLL1,E2F1,EGR2,EPHB3,HESX1,INA,KIF26A,LIMK2,LRRK2,MDGA1,NRCAM,NRP1,PADI2,PLXNA2,RAPGEF2,RTN4RL1,S1PR1,SELENOP,SEMA6B,SGPL1,SSBP3,SSTR2,SYNGR3,TACC2,TRABD2A,TYRO3,WDR62"} {"GO.ID":"GO:0006066","Term":"alcohol metabolic process","Annotated":282,"Significant":17,"Expected":17.03,"Rank in p.value_classic":3027,"p.value_elim":0.53513,"p.value_classic":0.53945,"genes":"APOL1,APOL2,CYP1A1,DAB2,DGAT2,DHFR,DHRS3,DHRS9,GCH1,GK,LRP5,NAAA,PLB1,PLEK,SCARF1,SOAT1,TTC39B"} {"GO.ID":"GO:0045930","Term":"negative regulation of mitotic cell cycle","Annotated":215,"Significant":29,"Expected":12.99,"Rank in p.value_classic":333,"p.value_elim":0.53564,"p.value_classic":0.00004,"genes":"AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CDC6,CDK1,CENPF,CHMP4C,CLSPN,DTL,EME1,FAM107A,GTSE1,KLF4,MAD2L1,MUC1,NDC80,NUF2,ORC1,OVOL1,PKMYT1,PML,SPC24,SPC25,TICRR,WEE1,ZWINT"} {"GO.ID":"GO:0032868","Term":"response to insulin","Annotated":215,"Significant":13,"Expected":12.99,"Rank in p.value_classic":3029,"p.value_elim":0.53575,"p.value_classic":0.53951,"genes":"APPL2,CEACAM1,EGR2,LYN,PDE3B,PDK4,PID1,PNPLA3,SESN3,SOCS1,STAT1,TNFRSF11A,TNFSF10"} {"GO.ID":"GO:0010001","Term":"glial cell differentiation","Annotated":215,"Significant":13,"Expected":12.99,"Rank in p.value_classic":3030,"p.value_elim":0.53575,"p.value_classic":0.53951,"genes":"CDK1,CDKN2C,DAB1,DLL1,EGR2,HAPLN3,KCNJ10,LYN,OLIG1,SLC45A3,TAL1,TNFRSF21,VCAN"} {"GO.ID":"GO:0040012","Term":"regulation of locomotion","Annotated":863,"Significant":70,"Expected":52.12,"Rank in p.value_classic":698,"p.value_elim":0.53666,"p.value_classic":0.0066,"genes":"ADAM8,ADORA3,AGT,AMOT,APPL2,ASCL2,ATP1B2,BCL6,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CEACAM1,CHRD,CSF1,CX3CR1,CXCL10,CXCR3,DAB2,EDN1,ENPP2,FAM107A,GHRL,GLIPR2,GLUL,GPR183,HBEGF,HGF,ICAM1,IFITM1,IL12A,JAK2,KIF26A,KITLG,KLF4,KLRK1,LRRK2,LYN,LYVE1,MIR503,MMP9,MTUS1,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,PADI2,PLXNA2,PRKX,PTGER4,PTPRU,RAPGEF2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,STMN1,SUCNR1,TMSB10,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0009966","Term":"regulation of signal transduction","Annotated":2540,"Significant":188,"Expected":153.4,"Rank in p.value_classic":491,"p.value_elim":0.53705,"p.value_classic":0.00098,"genes":"ACOD1,ADAM8,AGR2,AGT,AIM2,AKAP7,AMER1,AMOT,APOL3,APPL2,ATF3,AURKB,BANK1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,C3,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD28,CD300LF,CD40,CD74,CD80,CDH5,CEACAM1,CHAC1,CHRD,CIBAR1,CISH,CLEC6A,CRHBP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CYLD,DAB1,DAB2,DDX60,DEPTOR,DHRS3,DKK2,DLGAP3,DLL1,DTNBP1,DYNLT1,EDA,EDN1,F2RL3,FAM13A,FAS,FGD5,FSTL4,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GBP7,GHRL,GLIPR2,GPR183,GRAMD4,HBEGF,HELLS,HGF,HLA-DRB1,HLA-G,HTRA1,ICAM1,IFI35,IFIT5,IFT122,IL12A,IL1RN,IL7,IQGAP3,IRF1,IRF4,IRF7,ITSN1,JAK2,JAK3,KIF26A,KITLG,KREMEN1,LBH,LILRA2,LITAF,LRRK2,LYN,MAD2L1,MCF2L,MEFV,MIR503,MMP9,MUC1,MVP,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NRK,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP9,PDE3B,PDE4B,PID1,PIM1,PLEK,PLSCR1,PMAIP1,PML,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RGS18,RIPK2,RNF213,RSAD2,S100A13,SCIMP,SECTM1,SEPTIN4,SESN3,SLAMF1,SLC20A1,SOCS1,SOX17,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SYNE1,TAGAP,TANK,TGM2,TICAM2,TIFA,TIFAB,TLR7,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFSF10,TRABD2A,TRIM22,TRIM31,TSPAN15,TYRO3,UBD,VEGFC,VRK2,WDR76,ZBP1,ZC3H12A,ZWINT"} {"GO.ID":"GO:0007600","Term":"sensory perception","Annotated":333,"Significant":20,"Expected":20.11,"Rank in p.value_classic":3031,"p.value_elim":0.53925,"p.value_classic":0.54395,"genes":"ASIC1,ATP8B1,B2M,BIRC5,CLIC5,DHRS3,EPAS1,GRM8,KCNJ10,MARVELD2,MYO7B,OR2I1P,P2RX4,P2RX7,PKD1L3,PROK2,RTP4,SOBP,SPTBN4,USP53"} {"GO.ID":"GO:0072080","Term":"nephron tubule development","Annotated":81,"Significant":5,"Expected":4.89,"Rank in p.value_classic":3037,"p.value_elim":0.54353,"p.value_classic":0.54583,"genes":"AGT,CTNS,DLL1,MTSS1,STAT1"} {"GO.ID":"GO:0016925","Term":"protein sumoylation","Annotated":64,"Significant":4,"Expected":3.87,"Rank in p.value_classic":3032,"p.value_elim":0.5436,"p.value_classic":0.54564,"genes":"EGR2,IFIH1,PML,STX1A"} {"GO.ID":"GO:0003151","Term":"outflow tract morphogenesis","Annotated":64,"Significant":4,"Expected":3.87,"Rank in p.value_classic":3033,"p.value_elim":0.5436,"p.value_classic":0.54564,"genes":"DHRS3,EDN1,NRP1,SOX17"} {"GO.ID":"GO:0055013","Term":"cardiac muscle cell development","Annotated":64,"Significant":4,"Expected":3.87,"Rank in p.value_classic":3034,"p.value_elim":0.5436,"p.value_classic":0.54564,"genes":"ASB2,CDK1,CXADR,EDN1"} {"GO.ID":"GO:0014910","Term":"regulation of smooth muscle cell migration","Annotated":64,"Significant":4,"Expected":3.87,"Rank in p.value_classic":3035,"p.value_elim":0.5436,"p.value_classic":0.54564,"genes":"CCL5,MIR503,NR4A3,NRP1"} {"GO.ID":"GO:0051591","Term":"response to cAMP","Annotated":64,"Significant":4,"Expected":3.87,"Rank in p.value_classic":3036,"p.value_elim":0.5436,"p.value_classic":0.54564,"genes":"CRHBP,RAPGEF2,STAT1,THBD"} {"GO.ID":"GO:0072009","Term":"nephron epithelium development","Annotated":98,"Significant":6,"Expected":5.92,"Rank in p.value_classic":3045,"p.value_elim":0.54387,"p.value_classic":0.5464,"genes":"AGT,CTNS,DLL1,EDN1,MTSS1,STAT1"} {"GO.ID":"GO:0043280","Term":"positive regulation of cysteine-type endopeptidase activity involved in apoptotic process","Annotated":98,"Significant":6,"Expected":5.92,"Rank in p.value_classic":3046,"p.value_elim":0.54387,"p.value_classic":0.5464,"genes":"FAS,GRAMD4,JAK2,NLRP12,PMAIP1,TNFSF10"} {"GO.ID":"GO:0048565","Term":"digestive tract development","Annotated":98,"Significant":6,"Expected":5.92,"Rank in p.value_classic":3047,"p.value_elim":0.54387,"p.value_classic":0.5464,"genes":"AGR2,CYP1A1,DNAAF1,EPHB3,SOX17,TYMS"} {"GO.ID":"GO:0045667","Term":"regulation of osteoblast differentiation","Annotated":115,"Significant":7,"Expected":6.95,"Rank in p.value_classic":3048,"p.value_elim":0.54444,"p.value_classic":0.54718,"genes":"CHRD,HGF,IFITM1,LRP5,TMEM119,TNFAIP6,VEGFC"} {"GO.ID":"GO:0050905","Term":"neuromuscular process","Annotated":115,"Significant":7,"Expected":6.95,"Rank in p.value_classic":3049,"p.value_elim":0.54444,"p.value_classic":0.54718,"genes":"COMP,GCH1,GRIN3A,KCNJ2,PRRT2,SPTBN4,TIFAB"} {"GO.ID":"GO:0090090","Term":"negative regulation of canonical Wnt signaling pathway","Annotated":115,"Significant":7,"Expected":6.95,"Rank in p.value_classic":3050,"p.value_elim":0.54444,"p.value_classic":0.54718,"genes":"AMER1,CYLD,DAB2,DKK2,KREMEN1,PTPRU,SOX17"} {"GO.ID":"GO:0170034","Term":"L-amino acid biosynthetic process","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3038,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"DHFR,GLUL,SERINC5"} {"GO.ID":"GO:0022029","Term":"telencephalon cell migration","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3039,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"DAB1,LRRK2,MDGA1"} {"GO.ID":"GO:0050795","Term":"regulation of behavior","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3040,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"AIM2,GHRL,NR4A3"} {"GO.ID":"GO:0031297","Term":"replication fork processing","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3041,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"BRCA1,EME1,TONSL"} {"GO.ID":"GO:0048168","Term":"regulation of neuronal synaptic plasticity","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3042,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"EGR2,KCNJ10,RASGRF1"} {"GO.ID":"GO:0051403","Term":"stress-activated MAPK cascade","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3043,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"FAS,NOD2,SCIMP"} {"GO.ID":"GO:0007528","Term":"neuromuscular junction development","Annotated":47,"Significant":3,"Expected":2.84,"Rank in p.value_classic":3044,"p.value_elim":0.54445,"p.value_classic":0.5462,"genes":"COLQ,LRRK2,SPTBN4"} {"GO.ID":"GO:0008361","Term":"regulation of cell size","Annotated":166,"Significant":10,"Expected":10.03,"Rank in p.value_classic":3068,"p.value_elim":0.54679,"p.value_classic":0.55007,"genes":"DEPTOR,EDN1,FSTL4,IQGAP3,NRCAM,NRP1,P2RX7,PLEK,SEMA6B,SLC12A3"} {"GO.ID":"GO:0032200","Term":"telomere organization","Annotated":166,"Significant":10,"Expected":10.03,"Rank in p.value_classic":3069,"p.value_elim":0.54679,"p.value_classic":0.55007,"genes":"AURKB,CCNE2,EXO1,FEN1,GCH1,PARP3,PKIB,PML,RECQL4,XRN1"} {"GO.ID":"GO:0060391","Term":"positive regulation of SMAD protein signal transduction","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3051,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"DAB2,JAK2"} {"GO.ID":"GO:0009187","Term":"cyclic nucleotide metabolic process","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3052,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"NPR1,PDE4B"} {"GO.ID":"GO:0030149","Term":"sphingolipid catabolic process","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3053,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"ENPP2,SGPL1"} {"GO.ID":"GO:0099601","Term":"regulation of neurotransmitter receptor activity","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3054,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"CRHBP,DLGAP3"} {"GO.ID":"GO:0033280","Term":"response to vitamin D","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3055,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"CXCL10,PIM1"} {"GO.ID":"GO:0018345","Term":"protein palmitoylation","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3056,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"GLUL,ZDHHC19"} {"GO.ID":"GO:0061440","Term":"kidney vasculature development","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3057,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"EDN1,NRP1"} {"GO.ID":"GO:0061437","Term":"renal system vasculature development","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3058,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"EDN1,NRP1"} {"GO.ID":"GO:0048147","Term":"negative regulation of fibroblast proliferation","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3059,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"LTA,PARP10"} {"GO.ID":"GO:0021799","Term":"cerebral cortex radially oriented cell migration","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3060,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"DAB1,MDGA1"} {"GO.ID":"GO:0033687","Term":"osteoblast proliferation","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3061,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"LRP5,TMEM119"} {"GO.ID":"GO:0009069","Term":"serine family amino acid metabolic process","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3062,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"DHFR,SERINC5"} {"GO.ID":"GO:0048841","Term":"regulation of axon extension involved in axon guidance","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3063,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"NRP1,SEMA6B"} {"GO.ID":"GO:1902230","Term":"negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3064,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"CD74,MUC1"} {"GO.ID":"GO:0061842","Term":"microtubule organizing center localization","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3065,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"MAD2L1,PLXNA2"} {"GO.ID":"GO:0019369","Term":"arachidonic acid metabolic process","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3066,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"CYP1A1,EPHX1"} {"GO.ID":"GO:0051642","Term":"centrosome localization","Annotated":30,"Significant":2,"Expected":1.81,"Rank in p.value_classic":3067,"p.value_elim":0.54703,"p.value_classic":0.54844,"genes":"MAD2L1,PLXNA2"} {"GO.ID":"GO:0030900","Term":"forebrain development","Annotated":318,"Significant":19,"Expected":19.21,"Rank in p.value_classic":3070,"p.value_elim":0.5493,"p.value_classic":0.55387,"genes":"ATF5,ATP1B2,B2M,C21orf91,DAB1,E2F1,EPHB3,HESX1,KIF26A,LRRK2,MDGA1,NRP1,RAPGEF2,RTN4RL1,SEMA6B,SSTR2,TACC2,TYRO3,WDR62"} {"GO.ID":"GO:0050672","Term":"negative regulation of lymphocyte proliferation","Annotated":67,"Significant":14,"Expected":4.05,"Rank in p.value_classic":331,"p.value_elim":0.54967,"p.value_classic":0.00004,"genes":"BTN2A2,CD274,CD80,CTLA4,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,LYN,PDCD1LG2,TNFRSF14,TNFRSF21,TSPAN32"} {"GO.ID":"GO:0032945","Term":"negative regulation of mononuclear cell proliferation","Annotated":67,"Significant":14,"Expected":4.05,"Rank in p.value_classic":332,"p.value_elim":0.54967,"p.value_classic":0.00004,"genes":"BTN2A2,CD274,CD80,CTLA4,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,LYN,PDCD1LG2,TNFRSF14,TNFRSF21,TSPAN32"} {"GO.ID":"GO:0001701","Term":"in utero embryonic development","Annotated":352,"Significant":21,"Expected":21.26,"Rank in p.value_classic":3136,"p.value_elim":0.55137,"p.value_classic":0.55617,"genes":"AMOT,ASCL2,BCL2L11,E2F8,EDN1,EPAS1,GINS1,HORMAD1,KLF4,MAFF,NCAPG2,NPM2,PCDH12,PLCD3,PLPP4,POLB,RRM2,SCO2,SH3PXD2A,SOX17,XRCC2"} {"GO.ID":"GO:0045786","Term":"negative regulation of cell cycle","Annotated":352,"Significant":42,"Expected":21.26,"Rank in p.value_classic":309,"p.value_elim":0.55163,"p.value_classic":0.00002,"genes":"ATF5,AURKB,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNF,CDC45,CDC6,CDK1,CDT1,CENPF,CHMP4C,CLSPN,DTL,DTX3L,E2F1,E2F8,EME1,FAM107A,FBXO6,GTSE1,HLA-G,HORMAD1,KLF4,MAD2L1,MIR503,MUC1,NDC80,NUF2,ORC1,OVOL1,PARP9,PKMYT1,PML,SPC24,SPC25,TICRR,WDR76,WEE1,ZWINT"} {"GO.ID":"GO:0055007","Term":"cardiac muscle cell differentiation","Annotated":99,"Significant":6,"Expected":5.98,"Rank in p.value_classic":3137,"p.value_elim":0.55395,"p.value_classic":0.55648,"genes":"ASB2,CDK1,CXADR,DLL1,EDN1,SYNE1"} {"GO.ID":"GO:0014029","Term":"neural crest formation","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3071,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"EDN1"} {"GO.ID":"GO:0090385","Term":"phagosome-lysosome fusion","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3072,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"RAB20"} {"GO.ID":"GO:0034086","Term":"maintenance of sister chromatid cohesion","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3073,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DSCC1"} {"GO.ID":"GO:0034088","Term":"maintenance of mitotic sister chromatid cohesion","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3074,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DSCC1"} {"GO.ID":"GO:0045651","Term":"positive regulation of macrophage differentiation","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3075,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CSF1"} {"GO.ID":"GO:1900025","Term":"negative regulation of substrate adhesion-dependent cell spreading","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3076,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"GBP1"} {"GO.ID":"GO:0009130","Term":"pyrimidine nucleoside monophosphate biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3077,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"TYMS"} {"GO.ID":"GO:1905244","Term":"regulation of modification of synaptic structure","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3078,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CTTNBP2"} {"GO.ID":"GO:0090158","Term":"endoplasmic reticulum membrane organization","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3079,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"TRDN"} {"GO.ID":"GO:0009713","Term":"catechol-containing compound biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3080,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"GCH1"} {"GO.ID":"GO:0070166","Term":"enamel mineralization","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3081,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"FAM20A"} {"GO.ID":"GO:1902931","Term":"negative regulation of alcohol biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3082,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"PLEK"} {"GO.ID":"GO:1902902","Term":"negative regulation of autophagosome assembly","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3083,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"LRRK2"} {"GO.ID":"GO:0002029","Term":"desensitization of G protein-coupled receptor signaling pathway","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3084,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"NECAB2"} {"GO.ID":"GO:1901985","Term":"positive regulation of protein acetylation","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3085,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"PML"} {"GO.ID":"GO:0038065","Term":"collagen-activated signaling pathway","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3086,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"JAK2"} {"GO.ID":"GO:0005980","Term":"glycogen catabolic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3087,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"G6PC1"} {"GO.ID":"GO:1900424","Term":"regulation of defense response to bacterium","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3088,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"NOD2"} {"GO.ID":"GO:1905666","Term":"regulation of protein localization to endosome","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3089,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DTX3L"} {"GO.ID":"GO:0030575","Term":"nuclear body organization","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3090,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"PML"} {"GO.ID":"GO:1903054","Term":"negative regulation of extracellular matrix organization","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3091,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ANTXR1"} {"GO.ID":"GO:0032486","Term":"Rap protein signal transduction","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3092,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"RAPGEF2"} {"GO.ID":"GO:0042423","Term":"catecholamine biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3093,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"GCH1"} {"GO.ID":"GO:0022401","Term":"negative adaptation of signaling pathway","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3094,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"NECAB2"} {"GO.ID":"GO:2000310","Term":"regulation of NMDA receptor activity","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3095,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CRHBP"} {"GO.ID":"GO:0046049","Term":"UMP metabolic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3096,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DPYS"} {"GO.ID":"GO:1904350","Term":"regulation of protein catabolic process in the vacuole","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3097,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ATP13A2"} {"GO.ID":"GO:0043248","Term":"proteasome assembly","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3098,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"POMP"} {"GO.ID":"GO:0045019","Term":"negative regulation of nitric oxide biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3099,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ZC3H12A"} {"GO.ID":"GO:0042249","Term":"establishment of planar polarity of embryonic epithelium","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3100,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CELSR1"} {"GO.ID":"GO:1990822","Term":"basic amino acid transmembrane transport","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3101,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"SLC11A1"} {"GO.ID":"GO:0061307","Term":"cardiac neural crest cell differentiation involved in heart development","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3102,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"EDN1"} {"GO.ID":"GO:0061308","Term":"cardiac neural crest cell development involved in heart development","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3103,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"EDN1"} {"GO.ID":"GO:1904406","Term":"negative regulation of nitric oxide metabolic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3104,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ZC3H12A"} {"GO.ID":"GO:0018149","Term":"peptide cross-linking","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3105,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"TGM2"} {"GO.ID":"GO:0055089","Term":"fatty acid homeostasis","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3106,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DGAT2"} {"GO.ID":"GO:1904152","Term":"regulation of retrograde protein transport, ER to cytosol","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3107,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DERL3"} {"GO.ID":"GO:0034616","Term":"response to laminar fluid shear stress","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3108,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"KLF4"} {"GO.ID":"GO:0097468","Term":"programmed cell death in response to reactive oxygen species","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3109,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"HGF"} {"GO.ID":"GO:0048266","Term":"behavioral response to pain","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3110,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"P2RX4"} {"GO.ID":"GO:0070986","Term":"left/right axis specification","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3111,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"DLL1"} {"GO.ID":"GO:0001710","Term":"mesodermal cell fate commitment","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3112,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"KLF4"} {"GO.ID":"GO:0001711","Term":"endodermal cell fate commitment","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3113,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"SOX17"} {"GO.ID":"GO:0036151","Term":"phosphatidylcholine acyl-chain remodeling","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3114,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"PLB1"} {"GO.ID":"GO:1903265","Term":"positive regulation of tumor necrosis factor-mediated signaling pathway","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3115,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CASP4"} {"GO.ID":"GO:0009084","Term":"glutamine family amino acid biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3116,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"GLUL"} {"GO.ID":"GO:0097212","Term":"lysosomal membrane organization","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3117,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CHMP4C"} {"GO.ID":"GO:0071732","Term":"cellular response to nitric oxide","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3118,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CCNA2"} {"GO.ID":"GO:0034982","Term":"mitochondrial protein processing","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3119,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"LRRK2"} {"GO.ID":"GO:0046761","Term":"viral budding from plasma membrane","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3120,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CHMP4C"} {"GO.ID":"GO:0031643","Term":"positive regulation of myelination","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3121,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"EGR2"} {"GO.ID":"GO:0035234","Term":"ectopic germ cell programmed cell death","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3122,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"KITLG"} {"GO.ID":"GO:0071599","Term":"otic vesicle development","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3123,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"HESX1"} {"GO.ID":"GO:0072683","Term":"T cell extravasation","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3124,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ICAM1"} {"GO.ID":"GO:0043922","Term":"negative regulation by host of viral transcription","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3125,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CCL5"} {"GO.ID":"GO:0060080","Term":"inhibitory postsynaptic potential","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3126,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"INSYN2A"} {"GO.ID":"GO:1901741","Term":"positive regulation of myoblast fusion","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3127,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"CXCL9"} {"GO.ID":"GO:0015846","Term":"polyamine transport","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3128,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"ATP13A2"} {"GO.ID":"GO:0061635","Term":"regulation of protein complex stability","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3129,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"TAPBP"} {"GO.ID":"GO:1903671","Term":"negative regulation of sprouting angiogenesis","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3130,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"E2F2"} {"GO.ID":"GO:0006596","Term":"polyamine biosynthetic process","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3131,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"SAT1"} {"GO.ID":"GO:1902548","Term":"negative regulation of cellular response to vascular endothelial growth factor stimulus","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3132,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"IL12A"} {"GO.ID":"GO:0031958","Term":"corticosteroid receptor signaling pathway","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3133,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"JAK2"} {"GO.ID":"GO:0097623","Term":"potassium ion export across plasma membrane","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3134,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"KCNE5"} {"GO.ID":"GO:0010421","Term":"hydrogen peroxide-mediated programmed cell death","Annotated":13,"Significant":1,"Expected":0.79,"Rank in p.value_classic":3135,"p.value_elim":0.55431,"p.value_classic":0.55525,"genes":"HGF"} {"GO.ID":"GO:2001242","Term":"regulation of intrinsic apoptotic signaling pathway","Annotated":167,"Significant":10,"Expected":10.09,"Rank in p.value_classic":3139,"p.value_elim":0.55456,"p.value_classic":0.55785,"genes":"BCL2L11,CD74,CYLD,HELLS,LRRK2,MMP9,MUC1,PMAIP1,SEPTIN4,TIFAB"} {"GO.ID":"GO:0016241","Term":"regulation of macroautophagy","Annotated":167,"Significant":10,"Expected":10.09,"Rank in p.value_classic":3140,"p.value_elim":0.55456,"p.value_classic":0.55785,"genes":"ATP13A2,ATP6V0D2,CALCOCO2,LRRK2,NOD2,OPTN,RALB,RIPK2,RUFY4,SESN3"} {"GO.ID":"GO:0070936","Term":"protein K48-linked ubiquitination","Annotated":82,"Significant":5,"Expected":4.95,"Rank in p.value_classic":3138,"p.value_elim":0.55461,"p.value_classic":0.5569,"genes":"DTX3L,IFI27,NMI,TRIM31,UBE2T"} {"GO.ID":"GO:0097190","Term":"apoptotic signaling pathway","Annotated":545,"Significant":42,"Expected":32.92,"Rank in p.value_classic":1188,"p.value_elim":0.55462,"p.value_classic":0.06118,"genes":"AGT,ATF3,BCL2A1,BCL2L11,BCL2L14,BRCA1,CASP4,CD28,CD38,CD74,CHAC1,CTSL,CTSS,CX3CR1,CYLD,DEPTOR,E2F1,E2F2,FAS,G0S2,HELLS,HGF,ICAM1,IFI27,IL12A,IL7,JAK2,KITLG,LRRK2,MMP9,MUC1,NRP1,P2RX4,P2RX7,PMAIP1,PML,POLB,SEPTIN4,SGPL1,TIFAB,TMEM109,TNFSF10"} {"GO.ID":"GO:0071495","Term":"cellular response to endogenous stimulus","Annotated":1149,"Significant":72,"Expected":69.39,"Rank in p.value_classic":2444,"p.value_elim":0.55566,"p.value_classic":0.38689,"genes":"ACOD1,ACSL1,AGT,APPL2,BCL2L11,BRCA1,CASP4,CASP7,CASTOR1,CCL5,CCNA2,CDC6,CDH5,CEACAM1,CHRD,COMP,CRHBP,CTSL,CTSS,CX3CR1,DAB2,DLL1,DTNBP1,EDN1,EME1,FAM107A,FSTL4,GAREM1,GHRL,GNG2,HGF,HTRA1,ICAM1,IL12A,ITGB5,JAK2,JAK3,KLF4,LBH,LRRK2,LYN,MIR503,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,P2RX7,PADI2,PAQR8,PDE3B,PDK4,PID1,PML,PNPLA3,PTGER4,PXN,RAPGEF2,RIPK2,RXFP1,SESN3,SHCBP1,SLC4A7,SOCS1,SSTR2,STAMBPL1,STAT1,TGM2,TNFAIP6,VCAM1,VEGFC,XRN1"} {"GO.ID":"GO:0044419","Term":"biological process involved in interspecies interaction between organisms","Annotated":1288,"Significant":198,"Expected":77.79,"Rank in p.value_classic":7,"p.value_elim":0.55597,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,B2M,BANK1,BATF2,BATF3,C15orf48,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CARD16,CASP4,CASP7,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD40,CD74,CD80,CDK1,CEACAM1,CFB,CFH,CHMP4C,CIITA,CLEC10A,CLEC6A,CMPK2,COLEC12,CSF1,CSF2RB,CTSL,CTSS,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,DDX60,DTX3L,DYNLT1,EDN1,FAM20A,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GPR31,GRAMD4,GSDMA,GSDMD,H2BC21,HAVCR1,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-DRB1,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL18BP,IL27,IL31RA,IRF1,IRF4,IRF7,ISG20,ITGB5,JAK2,JAK3,KLRK1,LAG3,LILRA2,LITAF,LPL,LTA,LYN,MCOLN2,MEFV,MMP9,MSRB1,NCF1,NLRC5,NMI,NOD2,NRP1,NUB1,OAS2,OAS3,OPTN,P2RX7,PARP14,PARP9,PDCD1LG2,PDE4B,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PML,PPM1E,PTGER4,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RNF213,RSAD2,RTP4,SBNO2,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAP1,STAT1,STAT2,STMN1,TANK,TAP2,TBX21,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM255A,TNFRSF11A,TNFRSF14,TNFSF8,TPCN1,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,VCAM1,VWCE,WWP1,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0045666","Term":"positive regulation of neuron differentiation","Annotated":65,"Significant":4,"Expected":3.93,"Rank in p.value_classic":3141,"p.value_elim":0.55603,"p.value_classic":0.55807,"genes":"BCL6,DAB1,MMD,NRCAM"} {"GO.ID":"GO:0055017","Term":"cardiac muscle tissue growth","Annotated":65,"Significant":4,"Expected":3.93,"Rank in p.value_classic":3142,"p.value_elim":0.55603,"p.value_classic":0.55807,"genes":"CDK1,EDN1,PIM1,S1PR1"} {"GO.ID":"GO:0051153","Term":"regulation of striated muscle cell differentiation","Annotated":65,"Significant":4,"Expected":3.93,"Rank in p.value_classic":3143,"p.value_elim":0.55603,"p.value_classic":0.55807,"genes":"BHLHE41,DLL1,EDN1,TMEM119"} {"GO.ID":"GO:0001503","Term":"ossification","Annotated":353,"Significant":21,"Expected":21.32,"Rank in p.value_classic":3146,"p.value_elim":0.55675,"p.value_classic":0.56155,"genes":"ANKH,CHRD,COMP,CSF1,DHRS3,EGR2,HGF,IFITM1,KREMEN1,LRP5,P2RX7,PTGER4,S1PR1,SBNO2,SNX10,TMEM119,TNFAIP6,TNFRSF11A,VCAN,VEGFC,XYLT1"} {"GO.ID":"GO:0060113","Term":"inner ear receptor cell differentiation","Annotated":48,"Significant":3,"Expected":2.9,"Rank in p.value_classic":3144,"p.value_elim":0.55891,"p.value_classic":0.56066,"genes":"ATP8B1,DLL1,SLC4A7"} {"GO.ID":"GO:0030834","Term":"regulation of actin filament depolymerization","Annotated":48,"Significant":3,"Expected":2.9,"Rank in p.value_classic":3145,"p.value_elim":0.55891,"p.value_classic":0.56066,"genes":"PLEK,SCIN,SPTBN4"} {"GO.ID":"GO:0007420","Term":"brain development","Annotated":572,"Significant":34,"Expected":34.55,"Rank in p.value_classic":3149,"p.value_elim":0.55913,"p.value_classic":0.56529,"genes":"AATK,AIM2,ATF5,ATP1B2,B2M,C21orf91,CENPF,CTNS,CX3CR1,DAB1,DLL1,E2F1,EGR2,EPHB3,HESX1,INA,KIF26A,LRRK2,MDGA1,NRCAM,NRP1,PADI2,PLXNA2,RAPGEF2,RTN4RL1,S1PR1,SELENOP,SEMA6B,SSBP3,SSTR2,SYNGR3,TACC2,TYRO3,WDR62"} {"GO.ID":"GO:0007015","Term":"actin filament organization","Annotated":404,"Significant":24,"Expected":24.4,"Rank in p.value_classic":3147,"p.value_elim":0.55937,"p.value_classic":0.56451,"genes":"FAM107A,FSCN1,GHRL,IQGAP3,ITGB5,JAK2,MARCKSL1,MICAL2,MSRB1,MTSS1,MYO7B,NRP1,PLEK,PPM1E,PSTPIP2,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10,XIRP1"} {"GO.ID":"GO:0022603","Term":"regulation of anatomical structure morphogenesis","Annotated":728,"Significant":50,"Expected":43.97,"Rank in p.value_classic":1824,"p.value_elim":0.55964,"p.value_classic":0.1866,"genes":"AGT,AMOT,BCL6,BRCA1,C3,CCL13,CCL7,CD40,CDH5,CEACAM1,CSF1,CX3CR1,CXCL10,CYSLTR1,DAB1,DLL1,DTNBP1,E2F2,EDN1,ENPP2,EPHB3,FGD5,FMNL2,FSTL4,GHRL,GLUL,HGF,HLA-G,ITGA7,KLF4,LRRK2,MIR503,NPR1,NRP1,PDE3B,PID1,PLXNA2,PML,RAPGEF2,SDC2,SEMA6B,STAT1,STAT2,SYNE1,SYT1,THBS2,TNFSF13B,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0006644","Term":"phospholipid metabolic process","Annotated":320,"Significant":19,"Expected":19.33,"Rank in p.value_classic":3148,"p.value_elim":0.5606,"p.value_classic":0.56516,"genes":"CDS1,CISH,ENPP2,LCLAT1,LPL,NAAA,PCYT1A,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PNPLA3,SERINC5,SOCS1,TMEM150A,TNFAIP8L3"} {"GO.ID":"GO:0030334","Term":"regulation of cell migration","Annotated":801,"Significant":66,"Expected":48.38,"Rank in p.value_classic":676,"p.value_elim":0.56273,"p.value_classic":0.00584,"genes":"ADAM8,ADORA3,AGT,AMOT,APPL2,ASCL2,ATP1B2,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CEACAM1,CHRD,CSF1,CX3CR1,CXCL10,CXCR3,DAB2,EDN1,ENPP2,FAM107A,GLIPR2,GLUL,GPR183,HBEGF,HGF,ICAM1,IFITM1,IL12A,JAK2,KIF26A,KITLG,KLF4,KLRK1,LYN,LYVE1,MIR503,MMP9,MTUS1,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,PADI2,PLXNA2,PRKX,PTGER4,PTPRU,RAPGEF2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,STMN1,TMSB10,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0030534","Term":"adult behavior","Annotated":100,"Significant":6,"Expected":6.04,"Rank in p.value_classic":3166,"p.value_elim":0.56393,"p.value_classic":0.56646,"genes":"CRHBP,CTNS,DAB1,GHRL,KCNJ10,SPTBN4"} {"GO.ID":"GO:0061041","Term":"regulation of wound healing","Annotated":100,"Significant":6,"Expected":6.04,"Rank in p.value_classic":3167,"p.value_elim":0.56393,"p.value_classic":0.56646,"genes":"CEACAM1,EDN1,ENPP4,HBEGF,SERPING1,THBD"} {"GO.ID":"GO:0045601","Term":"regulation of endothelial cell differentiation","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3150,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"CDH5,CEACAM1"} {"GO.ID":"GO:0110110","Term":"positive regulation of animal organ morphogenesis","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3151,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"CSF1,EDN1"} {"GO.ID":"GO:0033146","Term":"regulation of intracellular estrogen receptor signaling pathway","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3152,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"BRCA1,LBH"} {"GO.ID":"GO:0043276","Term":"anoikis","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3153,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"E2F1,PDK4"} {"GO.ID":"GO:0035025","Term":"positive regulation of Rho protein signal transduction","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3154,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"F2RL3,MCF2L"} {"GO.ID":"GO:1904385","Term":"cellular response to angiotensin","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3155,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"AGT,CDC6"} {"GO.ID":"GO:1903170","Term":"negative regulation of calcium ion transmembrane transport","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3156,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"SRI,TRDN"} {"GO.ID":"GO:0019082","Term":"viral protein processing","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3157,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"PARP10,PARP9"} {"GO.ID":"GO:0048536","Term":"spleen development","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3158,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"BCL2L11,POLB"} {"GO.ID":"GO:0035751","Term":"regulation of lysosomal lumen pH","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3159,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"LRRK2,OCA2"} {"GO.ID":"GO:0051503","Term":"adenine nucleotide transport","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3160,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"ANKH,P2RX7"} {"GO.ID":"GO:0060043","Term":"regulation of cardiac muscle cell proliferation","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3161,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"CDK1,PIM1"} {"GO.ID":"GO:0006884","Term":"cell volume homeostasis","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3162,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"P2RX7,SLC12A3"} {"GO.ID":"GO:0032941","Term":"secretion by tissue","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3163,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"AGR2,TIFAB"} {"GO.ID":"GO:0140058","Term":"neuron projection arborization","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3164,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"LRRK2,NRP1"} {"GO.ID":"GO:0046685","Term":"response to arsenic-containing substance","Annotated":31,"Significant":2,"Expected":1.87,"Rank in p.value_classic":3165,"p.value_elim":0.56502,"p.value_classic":0.56643,"genes":"CYP1A1,ZC3H12A"} {"GO.ID":"GO:0034620","Term":"cellular response to unfolded protein","Annotated":83,"Significant":5,"Expected":5.01,"Rank in p.value_classic":3168,"p.value_elim":0.56554,"p.value_classic":0.56784,"genes":"AGR2,ATF3,BCL2L11,DERL3,OPTN"} {"GO.ID":"GO:0008593","Term":"regulation of Notch signaling pathway","Annotated":83,"Significant":5,"Expected":5.01,"Rank in p.value_classic":3169,"p.value_elim":0.56554,"p.value_classic":0.56784,"genes":"BCL6,CHAC1,DLL1,NOD2,TSPAN15"} {"GO.ID":"GO:0003073","Term":"regulation of systemic arterial blood pressure","Annotated":66,"Significant":4,"Expected":3.99,"Rank in p.value_classic":3171,"p.value_elim":0.56828,"p.value_classic":0.57032,"genes":"AGT,EDN1,SLC2A5,SUCNR1"} {"GO.ID":"GO:0032008","Term":"positive regulation of TOR signaling","Annotated":66,"Significant":4,"Expected":3.99,"Rank in p.value_classic":3172,"p.value_elim":0.56828,"p.value_classic":0.57032,"genes":"CASTOR1,CTNS,PIM1,STAMBPL1"} {"GO.ID":"GO:0098869","Term":"cellular oxidant detoxification","Annotated":66,"Significant":4,"Expected":3.99,"Rank in p.value_classic":3173,"p.value_elim":0.56828,"p.value_classic":0.57032,"genes":"DHFR,GCH1,GSTK1,LTC4S"} {"GO.ID":"GO:0001935","Term":"endothelial cell proliferation","Annotated":135,"Significant":8,"Expected":8.15,"Rank in p.value_classic":3174,"p.value_elim":0.57105,"p.value_classic":0.57397,"genes":"GHRL,IL12A,MIR503,NRP1,PRKX,PROK2,STAT1,VEGFC"} {"GO.ID":"GO:0031348","Term":"negative regulation of defense response","Annotated":212,"Significant":32,"Expected":12.8,"Rank in p.value_classic":237,"p.value_elim":0.57186,"p.value_classic":1.4e-06,"genes":"ACOD1,AURKB,CDH5,CEACAM1,CYLD,FGL2,GHRL,GPR31,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL22RA2,KLF4,LYN,MEFV,NLRC5,NLRP12,NMI,NOD2,OAS3,PARP14,PTGER4,SERPING1,SLAMF8,STAT2,TNFAIP6,TRAFD1,TYRO3"} {"GO.ID":"GO:0045814","Term":"negative regulation of gene expression, epigenetic","Annotated":118,"Significant":7,"Expected":7.13,"Rank in p.value_classic":3180,"p.value_elim":0.57214,"p.value_classic":0.57487,"genes":"BAZ1A,BCL6,BRCA1,HELLS,TDRD9,UHRF1,ZNFX1"} {"GO.ID":"GO:0071103","Term":"DNA conformation change","Annotated":88,"Significant":13,"Expected":5.31,"Rank in p.value_classic":558,"p.value_elim":0.57237,"p.value_classic":0.0023,"genes":"CDC45,CHTF18,DSCC1,GINS1,GINS2,MCM2,MCM4,MCM5,MCM6,MCM7,RAD54B,RECQL4,TOP2A"} {"GO.ID":"GO:0003015","Term":"heart process","Annotated":190,"Significant":20,"Expected":11.48,"Rank in p.value_classic":764,"p.value_elim":0.57245,"p.value_classic":0.0109,"genes":"ADORA3,AGT,ANK2,ATP1B2,CAMK2D,CXADR,EDN1,EPAS1,GCH1,GJD3,HBEGF,KCNE5,KCNJ2,P2RX4,PDE4B,SCN4B,SPTBN4,SRI,TRDN,ZC3H12A"} {"GO.ID":"GO:0050868","Term":"negative regulation of T cell activation","Annotated":99,"Significant":24,"Expected":5.98,"Rank in p.value_classic":136,"p.value_elim":0.57252,"p.value_classic":3.1e-09,"genes":"ASCL2,BCL6,BTN2A2,CD274,CD74,CD80,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,IRF1,JAK3,LAG3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,ZC3H12A"} {"GO.ID":"GO:0001954","Term":"positive regulation of cell-matrix adhesion","Annotated":49,"Significant":3,"Expected":2.96,"Rank in p.value_classic":3175,"p.value_elim":0.57308,"p.value_classic":0.57484,"genes":"CSF1,NRP1,S100A10"} {"GO.ID":"GO:0090303","Term":"positive regulation of wound healing","Annotated":49,"Significant":3,"Expected":2.96,"Rank in p.value_classic":3176,"p.value_elim":0.57308,"p.value_classic":0.57484,"genes":"ENPP4,HBEGF,THBD"} {"GO.ID":"GO:0071300","Term":"cellular response to retinoic acid","Annotated":49,"Significant":3,"Expected":2.96,"Rank in p.value_classic":3177,"p.value_elim":0.57308,"p.value_classic":0.57484,"genes":"KLF4,LYN,TESC"} {"GO.ID":"GO:0097300","Term":"programmed necrotic cell death","Annotated":49,"Significant":3,"Expected":2.96,"Rank in p.value_classic":3178,"p.value_elim":0.57308,"p.value_classic":0.57484,"genes":"CYLD,FAS,ZBP1"} {"GO.ID":"GO:0046173","Term":"polyol biosynthetic process","Annotated":49,"Significant":3,"Expected":2.96,"Rank in p.value_classic":3179,"p.value_elim":0.57308,"p.value_classic":0.57484,"genes":"DHFR,GCH1,PLEK"} {"GO.ID":"GO:0045785","Term":"positive regulation of cell adhesion","Annotated":412,"Significant":54,"Expected":24.88,"Rank in p.value_classic":173,"p.value_elim":0.5735,"p.value_classic":5.3e-08,"genes":"ADAM8,AGR2,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CHRD,CSF1,CYLD,DAB2,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL4I1,IL7,JAK2,KITLG,KLRK1,LYN,NOD2,NR4A3,NRP1,PDCD1LG2,PTPRU,RIPK2,RSU1,S100A10,SLAMF1,SOCS1,TGM2,TNFRSF14,TNFSF13B,TNFSF18,VCAM1"} {"GO.ID":"GO:0008203","Term":"cholesterol metabolic process","Annotated":101,"Significant":6,"Expected":6.1,"Rank in p.value_classic":3181,"p.value_elim":0.5738,"p.value_classic":0.57632,"genes":"APOL1,APOL2,LRP5,SCARF1,SOAT1,TTC39B"} {"GO.ID":"GO:0048525","Term":"negative regulation of viral process","Annotated":82,"Significant":19,"Expected":4.95,"Rank in p.value_classic":205,"p.value_elim":0.57447,"p.value_classic":3e-07,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CCL5,CIITA,FCN1,IFIH1,IFIT5,IFITM1,IFITM2,IFITM3,ISG20,OAS2,OAS3,PLSCR1,RSAD2,STAT1,TRIM31,ZNFX1"} {"GO.ID":"GO:0051963","Term":"regulation of synapse assembly","Annotated":84,"Significant":5,"Expected":5.07,"Rank in p.value_classic":3182,"p.value_elim":0.57634,"p.value_classic":0.57864,"genes":"COLQ,EPHB3,GHRL,MDGA1,THBS2"} {"GO.ID":"GO:0061326","Term":"renal tubule development","Annotated":84,"Significant":5,"Expected":5.07,"Rank in p.value_classic":3183,"p.value_elim":0.57634,"p.value_classic":0.57864,"genes":"AGT,CTNS,DLL1,MTSS1,STAT1"} {"GO.ID":"GO:0032526","Term":"response to retinoic acid","Annotated":84,"Significant":5,"Expected":5.07,"Rank in p.value_classic":3184,"p.value_elim":0.57634,"p.value_classic":0.57864,"genes":"CD38,IGF2R,KLF4,LYN,TESC"} {"GO.ID":"GO:0010466","Term":"negative regulation of peptidase activity","Annotated":84,"Significant":5,"Expected":5.07,"Rank in p.value_classic":3185,"p.value_elim":0.57634,"p.value_classic":0.57864,"genes":"CARD16,KLF4,LAMP3,MMP9,SERPING1"} {"GO.ID":"GO:0002474","Term":"antigen processing and presentation of peptide antigen via MHC class I","Annotated":33,"Significant":12,"Expected":1.99,"Rank in p.value_classic":201,"p.value_elim":0.57645,"p.value_classic":2.4e-07,"genes":"B2M,ERAP2,HLA-A,HLA-B,HLA-C,HLA-E,HLA-F,HLA-G,TAP1,TAP2,TAPBP,TAPBPL"} {"GO.ID":"GO:0034767","Term":"positive regulation of monoatomic ion transmembrane transport","Annotated":114,"Significant":16,"Expected":6.89,"Rank in p.value_classic":514,"p.value_elim":0.57685,"p.value_classic":0.00133,"genes":"ABCB1,ANK2,ATP1B2,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,KCNE5,KCNJ2,P2RX4,P2RX7,SRI,TESC,TRDN"} {"GO.ID":"GO:0031331","Term":"positive regulation of cellular catabolic process","Annotated":306,"Significant":18,"Expected":18.48,"Rank in p.value_classic":3187,"p.value_elim":0.57706,"p.value_classic":0.58147,"genes":"ADAM8,CALCOCO2,DEPTOR,DTX3L,GTPBP1,LRRK2,MEFV,NOD2,OPTN,P2RX7,RALB,RIPK2,RUFY4,SAMD4A,SESN3,TPCN1,TRIM22,ZC3H12A"} {"GO.ID":"GO:0046635","Term":"positive regulation of alpha-beta T cell activation","Annotated":61,"Significant":12,"Expected":3.68,"Rank in p.value_classic":402,"p.value_elim":0.57726,"p.value_classic":0.00024,"genes":"CD28,CD80,CD83,HLA-A,HLA-DRA,HLA-DRB1,HLA-E,IL12A,IL12RB1,JAK2,RIPK2,SOCS1"} {"GO.ID":"GO:1901888","Term":"regulation of cell junction assembly","Annotated":170,"Significant":10,"Expected":10.27,"Rank in p.value_classic":3186,"p.value_elim":0.57756,"p.value_classic":0.58083,"genes":"AGT,COLQ,EPHB3,FAM107A,GHRL,MDGA1,NRP1,RAPGEF2,S100A10,THBS2"} {"GO.ID":"GO:0003008","Term":"system process","Annotated":1304,"Significant":91,"Expected":78.76,"Rank in p.value_classic":1270,"p.value_elim":0.57808,"p.value_classic":0.07712,"genes":"ABCB1,ABCG2,ADORA3,AGT,ANK2,ASIC1,ATP1B2,ATP8B1,B2M,BIRC5,CAMK2D,CBR3,CD38,CDH5,CEACAM1,CLIC5,COMP,CRHBP,CTNS,CX3CR1,CXADR,CXCL10,CYSLTR1,DAB2,DHRS3,DLGAP3,DLL1,ECEL1,EDN1,EGR2,EPAS1,ERAP2,FAM107A,FEN1,GABRA3,GCH1,GCNT3,GHRL,GJD3,GRIN3A,GRM8,HBEGF,HCAR2,HLA-DRA,HRH2,INSYN2A,KCNE5,KCNJ10,KCNJ2,LRP5,LRRK2,MARVELD2,MYO7B,MYOF,MYOZ2,NOD2,NPR1,NR4A3,NRCAM,OR2I1P,P2RX4,P2RX7,PDE4B,PKD1L3,PROK2,PRRT2,RASGRF1,RTP4,S1PR1,SCN4B,SCO2,SERPING1,SLC12A3,SLC2A5,SNX10,SOBP,SPTBN4,SRI,SSPN,SSTR2,STAT1,STX1A,SUCNR1,SYNE1,TIFAB,TNFRSF21,TRDN,TYMP,USP53,VEGFC,ZC3H12A"} {"GO.ID":"GO:2000191","Term":"regulation of fatty acid transport","Annotated":25,"Significant":5,"Expected":1.51,"Rank in p.value_classic":821,"p.value_elim":0.57959,"p.value_classic":0.01535,"genes":"ACSL1,EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0097035","Term":"regulation of membrane lipid distribution","Annotated":50,"Significant":7,"Expected":3.02,"Rank in p.value_classic":973,"p.value_elim":0.5797,"p.value_classic":0.02957,"genes":"ABCB1,ANO4,ATP8B1,P2RX7,PLSCR1,PLSCR4,XKR6"} {"GO.ID":"GO:0014032","Term":"neural crest cell development","Annotated":67,"Significant":4,"Expected":4.05,"Rank in p.value_classic":3250,"p.value_elim":0.58033,"p.value_classic":0.58238,"genes":"EDN1,KITLG,NRP1,SEMA6B"} {"GO.ID":"GO:1901606","Term":"alpha-amino acid catabolic process","Annotated":67,"Significant":4,"Expected":4.05,"Rank in p.value_classic":3251,"p.value_elim":0.58033,"p.value_classic":0.58238,"genes":"GLUL,IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0043279","Term":"response to alkaloid","Annotated":67,"Significant":4,"Expected":4.05,"Rank in p.value_classic":3252,"p.value_elim":0.58033,"p.value_classic":0.58238,"genes":"CASP7,CCNA2,CRHBP,TGM2"} {"GO.ID":"GO:0021954","Term":"central nervous system neuron development","Annotated":67,"Significant":4,"Expected":4.05,"Rank in p.value_classic":3253,"p.value_elim":0.58033,"p.value_classic":0.58238,"genes":"EPHB3,NRP1,RAPGEF2,SPTBN4"} {"GO.ID":"GO:0009190","Term":"cyclic nucleotide biosynthetic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3188,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"NPR1"} {"GO.ID":"GO:0009173","Term":"pyrimidine ribonucleoside monophosphate metabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3189,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"DPYS"} {"GO.ID":"GO:0035641","Term":"locomotory exploration behavior","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3190,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"LRRK2"} {"GO.ID":"GO:1904925","Term":"positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3191,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"OPTN"} {"GO.ID":"GO:1905269","Term":"positive regulation of chromatin organization","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3192,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TAL1"} {"GO.ID":"GO:0023058","Term":"adaptation of signaling pathway","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3193,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"NECAB2"} {"GO.ID":"GO:0099149","Term":"regulation of postsynaptic neurotransmitter receptor internalization","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3194,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"SYNE1"} {"GO.ID":"GO:0023019","Term":"signal transduction involved in regulation of gene expression","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3195,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"SOX17"} {"GO.ID":"GO:0009251","Term":"glucan catabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3196,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"G6PC1"} {"GO.ID":"GO:0003091","Term":"renal water homeostasis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3197,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CTNS"} {"GO.ID":"GO:0032048","Term":"cardiolipin metabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3198,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"LCLAT1"} {"GO.ID":"GO:0010715","Term":"regulation of extracellular matrix disassembly","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3199,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"FSCN1"} {"GO.ID":"GO:0002091","Term":"negative regulation of receptor internalization","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3200,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"NECAB2"} {"GO.ID":"GO:0035973","Term":"aggrephagy","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3201,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"MAP1LC3C"} {"GO.ID":"GO:0060253","Term":"negative regulation of glial cell proliferation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3202,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"ASCL2"} {"GO.ID":"GO:0060231","Term":"mesenchymal to epithelial transition","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3203,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"STAT1"} {"GO.ID":"GO:0072077","Term":"renal vesicle morphogenesis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3204,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"STAT1"} {"GO.ID":"GO:0061050","Term":"regulation of cell growth involved in cardiac muscle cell development","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3205,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"EDN1"} {"GO.ID":"GO:0042359","Term":"vitamin D metabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3206,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CYP1A1"} {"GO.ID":"GO:0071027","Term":"nuclear RNA surveillance","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3207,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"XRN1"} {"GO.ID":"GO:0070885","Term":"negative regulation of calcineurin-NFAT signaling cascade","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3208,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"MYOZ2"} {"GO.ID":"GO:0090520","Term":"sphingolipid mediated signaling pathway","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3209,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"S1PR1"} {"GO.ID":"GO:0032488","Term":"Cdc42 protein signal transduction","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3210,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"NRP1"} {"GO.ID":"GO:2000345","Term":"regulation of hepatocyte proliferation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3211,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CEACAM1"} {"GO.ID":"GO:0043101","Term":"purine-containing compound salvage","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3212,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"PRTFDC1"} {"GO.ID":"GO:0042402","Term":"cellular biogenic amine catabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3213,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"SAT1"} {"GO.ID":"GO:1901017","Term":"negative regulation of potassium ion transmembrane transporter activity","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3214,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"KCNE5"} {"GO.ID":"GO:0033762","Term":"response to glucagon","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3215,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CCNA2"} {"GO.ID":"GO:0061323","Term":"cell proliferation involved in heart morphogenesis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3216,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"PIM1"} {"GO.ID":"GO:2000136","Term":"regulation of cell proliferation involved in heart morphogenesis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3217,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"PIM1"} {"GO.ID":"GO:0097396","Term":"response to interleukin-17","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3218,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CXCL10"} {"GO.ID":"GO:0097398","Term":"cellular response to interleukin-17","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3219,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CXCL10"} {"GO.ID":"GO:0007351","Term":"tripartite regional subdivision","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3220,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TIFAB"} {"GO.ID":"GO:0033599","Term":"regulation of mammary gland epithelial cell proliferation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3221,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"IQGAP3"} {"GO.ID":"GO:0106057","Term":"negative regulation of calcineurin-mediated signaling","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3222,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"MYOZ2"} {"GO.ID":"GO:0051127","Term":"positive regulation of actin nucleation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3223,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"SCIN"} {"GO.ID":"GO:0043584","Term":"nose development","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3224,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"HESX1"} {"GO.ID":"GO:0046459","Term":"short-chain fatty acid metabolic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3225,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"ACOT4"} {"GO.ID":"GO:0043501","Term":"skeletal muscle adaptation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3226,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"MYOZ2"} {"GO.ID":"GO:0050930","Term":"induction of positive chemotaxis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3227,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"VEGFC"} {"GO.ID":"GO:2001028","Term":"positive regulation of endothelial cell chemotaxis","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3228,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"P2RX4"} {"GO.ID":"GO:0021859","Term":"pyramidal neuron differentiation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3229,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"BCL6"} {"GO.ID":"GO:0043652","Term":"engulfment of apoptotic cell","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3230,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"XKR6"} {"GO.ID":"GO:0033631","Term":"cell-cell adhesion mediated by integrin","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3231,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CCL5"} {"GO.ID":"GO:0046184","Term":"aldehyde biosynthetic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3232,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"DAB2"} {"GO.ID":"GO:0007100","Term":"mitotic centrosome separation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3233,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"KIF11"} {"GO.ID":"GO:0032674","Term":"regulation of interleukin-5 production","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3234,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TNFRSF21"} {"GO.ID":"GO:0032634","Term":"interleukin-5 production","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3235,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TNFRSF21"} {"GO.ID":"GO:2000651","Term":"positive regulation of sodium ion transmembrane transporter activity","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3236,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TESC"} {"GO.ID":"GO:0031649","Term":"heat generation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3237,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TNFRSF11A"} {"GO.ID":"GO:0046753","Term":"non-lytic viral release","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3238,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"CHMP4C"} {"GO.ID":"GO:0008595","Term":"anterior/posterior axis specification, embryo","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3239,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"TIFAB"} {"GO.ID":"GO:0051580","Term":"regulation of neurotransmitter uptake","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3240,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"SYNGR3"} {"GO.ID":"GO:1901203","Term":"positive regulation of extracellular matrix assembly","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3241,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"AGT"} {"GO.ID":"GO:0035721","Term":"intraciliary retrograde transport","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3242,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"IFT122"} {"GO.ID":"GO:0006700","Term":"C21-steroid hormone biosynthetic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3243,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"DAB2"} {"GO.ID":"GO:1903543","Term":"positive regulation of exosomal secretion","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3244,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"ATP13A2"} {"GO.ID":"GO:0015867","Term":"ATP transport","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3245,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"ANKH"} {"GO.ID":"GO:0051645","Term":"Golgi localization","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3246,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"DAB1"} {"GO.ID":"GO:2001169","Term":"regulation of ATP biosynthetic process","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3247,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"PID1"} {"GO.ID":"GO:0035542","Term":"regulation of SNARE complex assembly","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3248,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"PRRT2"} {"GO.ID":"GO:0045579","Term":"positive regulation of B cell differentiation","Annotated":14,"Significant":1,"Expected":0.85,"Rank in p.value_classic":3249,"p.value_elim":0.58118,"p.value_classic":0.58213,"genes":"IL7"} {"GO.ID":"GO:0001678","Term":"intracellular glucose homeostasis","Annotated":119,"Significant":7,"Expected":7.19,"Rank in p.value_classic":3267,"p.value_elim":0.58119,"p.value_classic":0.58392,"genes":"GHRL,HLA-DRB1,ICAM1,LRP5,NCF1,SIDT2,SRI"} {"GO.ID":"GO:0001953","Term":"negative regulation of cell-matrix adhesion","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3254,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"BCL6,FAM107A"} {"GO.ID":"GO:1901661","Term":"quinone metabolic process","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3255,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"AIFM2,CBR3"} {"GO.ID":"GO:0062098","Term":"regulation of programmed necrotic cell death","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3256,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"CYLD,ZBP1"} {"GO.ID":"GO:0032350","Term":"regulation of hormone metabolic process","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3257,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"CTNS,DAB2"} {"GO.ID":"GO:0008053","Term":"mitochondrial fusion","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3258,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"BCL2A1,PID1"} {"GO.ID":"GO:0042491","Term":"inner ear auditory receptor cell differentiation","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3259,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"DLL1,SLC4A7"} {"GO.ID":"GO:0072337","Term":"modified amino acid transport","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3260,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"CTNS,SLC6A12"} {"GO.ID":"GO:0010907","Term":"positive regulation of glucose metabolic process","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3261,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"PMAIP1,SLC45A3"} {"GO.ID":"GO:0019068","Term":"virion assembly","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3262,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"CHMP4C,USP6NL"} {"GO.ID":"GO:0021515","Term":"cell differentiation in spinal cord","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3263,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"MDGA1,TAL1"} {"GO.ID":"GO:0045776","Term":"negative regulation of blood pressure","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3264,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"GCH1,VEGFC"} {"GO.ID":"GO:0051602","Term":"response to electrical stimulus","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3265,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"GHRL,P2RX7"} {"GO.ID":"GO:0007616","Term":"long-term memory","Annotated":32,"Significant":2,"Expected":1.93,"Rank in p.value_classic":3266,"p.value_elim":0.58248,"p.value_classic":0.5839,"genes":"CTNS,RASGRF1"} {"GO.ID":"GO:0007498","Term":"mesoderm development","Annotated":102,"Significant":6,"Expected":6.16,"Rank in p.value_classic":3268,"p.value_elim":0.58356,"p.value_classic":0.58608,"genes":"JAK2,KLF4,OVOL1,SECTM1,SSBP3,TAL1"} {"GO.ID":"GO:0060972","Term":"left/right pattern formation","Annotated":102,"Significant":6,"Expected":6.16,"Rank in p.value_classic":3269,"p.value_elim":0.58356,"p.value_classic":0.58608,"genes":"ASB2,DLL1,DNAAF1,IFT122,MICAL2,SOX17"} {"GO.ID":"GO:0051222","Term":"positive regulation of protein transport","Annotated":205,"Significant":12,"Expected":12.38,"Rank in p.value_classic":3270,"p.value_elim":0.58359,"p.value_classic":0.58718,"genes":"ADAM8,ATP13A2,CD38,CDK1,GHRL,HCAR2,HLA-DRB1,JAK2,P2RX7,SRI,VEGFC,ZC3H12A"} {"GO.ID":"GO:0000003","Term":"reproduction","Annotated":1019,"Significant":72,"Expected":61.54,"Rank in p.value_classic":1327,"p.value_elim":0.586,"p.value_classic":0.08844,"genes":"ACOD1,ADGB,ANTXR1,APOL2,BCL2L11,BCL6,C3,CCNE2,CD38,CDC25A,CDK1,CLIC5,CRHBP,CSF1,CXADR,CYP1A1,DAZL,DMC1,E2F8,EDN1,EME1,EXO1,GHRL,HESX1,HORMAD1,IDO1,IGF2R,KITLG,LIMK2,LRRK2,MAFF,MEIKIN,MERTK,MMP9,NCAPH,NDC80,NPM2,NUF2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PKMYT1,PLB1,PROK2,PZP,RAD54B,RAD54L,RHOBTB3,RXFP1,SELENOP,SEPTIN4,SGPL1,SOX17,SPATA9,SPTBN4,SSTR2,SYNE1,SYT6,TBATA,TDRD9,THBD,TIFAB,TMEM119,TNFAIP6,TNFSF10,TOP2A,TYRO3,XRCC2,ZMYND15,ZWINT"} {"GO.ID":"GO:0019233","Term":"sensory perception of pain","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3272,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"P2RX4,P2RX7,PROK2"} {"GO.ID":"GO:0060420","Term":"regulation of heart growth","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3273,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"CDK1,EDN1,PIM1"} {"GO.ID":"GO:0009880","Term":"embryonic pattern specification","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3274,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"DLL1,NRP1,TIFAB"} {"GO.ID":"GO:0042490","Term":"mechanoreceptor differentiation","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3275,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"ATP8B1,DLL1,SLC4A7"} {"GO.ID":"GO:0001756","Term":"somitogenesis","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3276,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"DLL1,PLXNA2,XRCC2"} {"GO.ID":"GO:0019083","Term":"viral transcription","Annotated":50,"Significant":3,"Expected":3.02,"Rank in p.value_classic":3277,"p.value_elim":0.58697,"p.value_classic":0.58873,"genes":"CCL5,IFITM3,TRIM31"} {"GO.ID":"GO:2001237","Term":"negative regulation of extrinsic apoptotic signaling pathway","Annotated":85,"Significant":5,"Expected":5.13,"Rank in p.value_classic":3278,"p.value_elim":0.587,"p.value_classic":0.58929,"genes":"BRCA1,HGF,ICAM1,IL7,NRP1"} {"GO.ID":"GO:0045995","Term":"regulation of embryonic development","Annotated":85,"Significant":5,"Expected":5.13,"Rank in p.value_classic":3279,"p.value_elim":0.587,"p.value_classic":0.58929,"genes":"AMOT,CDK1,DLL1,HESX1,SOX17"} {"GO.ID":"GO:0018107","Term":"peptidyl-threonine phosphorylation","Annotated":85,"Significant":5,"Expected":5.13,"Rank in p.value_classic":3280,"p.value_elim":0.587,"p.value_classic":0.58929,"genes":"CAMK2D,CDK1,LMTK2,LRRK2,RIPK2"} {"GO.ID":"GO:0006766","Term":"vitamin metabolic process","Annotated":85,"Significant":5,"Expected":5.13,"Rank in p.value_classic":3281,"p.value_elim":0.587,"p.value_classic":0.58929,"genes":"AIFM2,CBR3,CYP1A1,DHFR,MTHFD2"} {"GO.ID":"GO:0016579","Term":"protein deubiquitination","Annotated":85,"Significant":5,"Expected":5.13,"Rank in p.value_classic":3282,"p.value_elim":0.587,"p.value_classic":0.58929,"genes":"CYLD,OTUD1,STAMBPL1,TANK,ZC3H12A"} {"GO.ID":"GO:0035265","Term":"organ growth","Annotated":137,"Significant":8,"Expected":8.27,"Rank in p.value_classic":3283,"p.value_elim":0.58794,"p.value_classic":0.59086,"genes":"BCL2L11,CDK1,COMP,DLL1,EDN1,IL7,PIM1,S1PR1"} {"GO.ID":"GO:0000165","Term":"MAPK cascade","Annotated":620,"Significant":55,"Expected":37.45,"Rank in p.value_classic":572,"p.value_elim":0.58882,"p.value_classic":0.00256,"genes":"ADAM8,AGT,ATF3,BANK1,BTN2A2,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD40,CD74,CDK1,CEACAM1,CYLD,DAB2,EDN1,FAS,GADD45B,GAREM1,GBP1,GHRL,GLIPR2,GPR183,HESX1,HGF,HLA-DRB1,ICAM1,IL31RA,IQGAP3,JAK2,KARS1,LBH,LRRK2,LYN,MIR503,NCF1,NECAB2,NLRP12,NOD2,NRK,NRP1,OSM,P2RX7,PTGER4,RAPGEF2,RIPK2,SCIMP,SLAMF1,TLR7,TNFAIP8L3,TNFRSF11A,VRK2,ZC3H12A"} {"GO.ID":"GO:0042157","Term":"lipoprotein metabolic process","Annotated":120,"Significant":7,"Expected":7.25,"Rank in p.value_classic":3285,"p.value_elim":0.59015,"p.value_classic":0.59287,"genes":"APOL1,APOL2,APOL3,APOL4,APOL6,GLUL,ZDHHC19"} {"GO.ID":"GO:0002682","Term":"regulation of immune system process","Annotated":1247,"Significant":176,"Expected":75.31,"Rank in p.value_classic":16,"p.value_elim":0.59016,"p.value_classic":1.7e-28,"genes":"ACOD1,ADAM8,AIM2,APPL2,ASCL2,AURKB,B2M,BANK1,BCL6,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CCL5,CCL7,CCL8,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CD83,CEACAM1,CFB,CFH,CLEC6A,COLEC12,CR1L,CSF1,CTLA4,CTSS,CX3CR1,CXCL10,CXCR3,CYLD,DDX60,DLL1,EDN1,FAXDC2,FCN1,FGL1,FGL2,FYB1,GBP1,GBP2,GBP5,GPR183,GPR31,GRAMD4,HAVCR1,HCAR2,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IFIH1,IL12A,IL12RB1,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KARS1,KITLG,KLRK1,LAG3,LILRA2,LILRB3,LITAF,LRRK2,LTA,LYN,LYVE1,MEFV,MERTK,MTUS1,NCF1,NLRC5,NMI,NOD2,NR4A3,OAS3,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDCD1,PDCD1LG2,PDE4B,PLPP4,PLSCR1,PTGER4,PYHIN1,RIPK2,RSAD2,SCIMP,SCIN,SERPING1,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SOCS1,STAP1,STAT1,STAT2,TAL1,TAP2,TAPBPL,TBX21,TESC,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TMEM176A,TMEM176B,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TRAFD1,TRIM31,TSPAN32,TYRO3,VCAM1,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:1902532","Term":"negative regulation of intracellular signal transduction","Annotated":485,"Significant":33,"Expected":29.29,"Rank in p.value_classic":2097,"p.value_elim":0.59103,"p.value_classic":0.26132,"genes":"AGT,AIM2,ATF3,BANK1,BCL6,BTN2A2,CASTOR1,CD74,CYLD,DAB2,DEPTOR,GBP1,HELLS,HLA-G,IFI35,LITAF,LRRK2,LYN,MIR503,MMP9,MUC1,MYOZ2,NLRP12,NMI,OPTN,P2RX7,PDE3B,PLEK,SESN3,STAT1,STMN1,TANK,ZC3H12A"} {"GO.ID":"GO:0007004","Term":"telomere maintenance via telomerase","Annotated":68,"Significant":4,"Expected":4.11,"Rank in p.value_classic":3286,"p.value_elim":0.59219,"p.value_classic":0.59423,"genes":"AURKB,GCH1,PKIB,XRN1"} {"GO.ID":"GO:1990845","Term":"adaptive thermogenesis","Annotated":138,"Significant":8,"Expected":8.33,"Rank in p.value_classic":3287,"p.value_elim":0.59627,"p.value_classic":0.59917,"genes":"ACSL1,APPL2,EPAS1,G0S2,GHRL,IL15,IRF4,JAK2"} {"GO.ID":"GO:0030510","Term":"regulation of BMP signaling pathway","Annotated":86,"Significant":5,"Expected":5.19,"Rank in p.value_classic":3288,"p.value_elim":0.59751,"p.value_classic":0.59979,"genes":"CDH5,CHRD,FSTL4,HTRA1,TNFAIP6"} {"GO.ID":"GO:0014014","Term":"negative regulation of gliogenesis","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3289,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"ASCL2,DAB1"} {"GO.ID":"GO:0060323","Term":"head morphogenesis","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3290,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"SGPL1,SSBP3"} {"GO.ID":"GO:0090278","Term":"negative regulation of peptide hormone secretion","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3291,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CRHBP,GHRL"} {"GO.ID":"GO:0010828","Term":"positive regulation of glucose transmembrane transport","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3292,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"C3,NR4A3"} {"GO.ID":"GO:0045920","Term":"negative regulation of exocytosis","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3293,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CEACAM1,HLA-F"} {"GO.ID":"GO:0060218","Term":"hematopoietic stem cell differentiation","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3294,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"OSM,TAL1"} {"GO.ID":"GO:0010573","Term":"vascular endothelial growth factor production","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3295,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"BRCA1,C3"} {"GO.ID":"GO:0010518","Term":"positive regulation of phospholipase activity","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3296,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CCL5,ITK"} {"GO.ID":"GO:0043243","Term":"positive regulation of protein-containing complex disassembly","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3297,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CALCOCO2,PLEK"} {"GO.ID":"GO:0043537","Term":"negative regulation of blood vessel endothelial cell migration","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3298,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"KLF4,MIR503"} {"GO.ID":"GO:1902745","Term":"positive regulation of lamellipodium organization","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3299,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"ENPP2,FSCN1"} {"GO.ID":"GO:1901797","Term":"negative regulation of signal transduction by p53 class mediator","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3300,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CD74,MUC1"} {"GO.ID":"GO:1901861","Term":"regulation of muscle tissue development","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3301,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CENPF,DLL1"} {"GO.ID":"GO:0021955","Term":"central nervous system neuron axonogenesis","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3302,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"EPHB3,SPTBN4"} {"GO.ID":"GO:0006516","Term":"glycoprotein catabolic process","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3303,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"CTSL,FBXO6"} {"GO.ID":"GO:0046627","Term":"negative regulation of insulin receptor signaling pathway","Annotated":33,"Significant":2,"Expected":1.99,"Rank in p.value_classic":3304,"p.value_elim":0.59943,"p.value_classic":0.60084,"genes":"PID1,SOCS1"} {"GO.ID":"GO:0002090","Term":"regulation of receptor internalization","Annotated":51,"Significant":3,"Expected":3.08,"Rank in p.value_classic":3305,"p.value_elim":0.60057,"p.value_classic":0.60232,"genes":"DTNBP1,NECAB2,SYNE1"} {"GO.ID":"GO:0097479","Term":"synaptic vesicle localization","Annotated":51,"Significant":3,"Expected":3.08,"Rank in p.value_classic":3306,"p.value_elim":0.60057,"p.value_classic":0.60232,"genes":"DNM1,DTNBP1,LRRK2"} {"GO.ID":"GO:0006334","Term":"nucleosome assembly","Annotated":69,"Significant":4,"Expected":4.17,"Rank in p.value_classic":3307,"p.value_elim":0.60385,"p.value_classic":0.60589,"genes":"BAZ1A,CHAF1B,H2BC21,MCM2"} {"GO.ID":"GO:0001816","Term":"cytokine production","Annotated":658,"Significant":99,"Expected":39.74,"Rank in p.value_classic":31,"p.value_elim":0.60387,"p.value_classic":8.9e-18,"genes":"ACOD1,ADAM8,AGT,AIM2,APPL2,B2M,BANK1,BCL6,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CARD16,CD274,CD28,CD74,CD80,CD83,CEACAM1,CLEC6A,CLEC9A,CX3CR1,CYLD,DLL1,FCN1,GBP1,GBP5,GBP7,GHRL,GSDMD,HGF,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL7,IRF1,IRF4,IRF7,ITK,JAK2,JAK3,KLF4,KLRK1,LAG3,LILRA2,LITAF,LPL,LRRK2,LTA,LYN,MCOLN2,MEFV,MERTK,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OSM,P2RX7,PDCD1LG2,PDE4B,PML,PTGER4,RELB,RIPK2,RSAD2,S100A13,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,STAT1,TANK,TBX21,TICAM2,TLR5,TLR7,TLR8,TNFRSF14,TNFRSF21,XAF1,ZC3H12A"} {"GO.ID":"GO:0035966","Term":"response to topologically incorrect protein","Annotated":139,"Significant":8,"Expected":8.39,"Rank in p.value_classic":3368,"p.value_elim":0.60451,"p.value_classic":0.60741,"genes":"AGR2,ATF3,BCL2L11,CHAC1,COMP,DERL3,FBXO6,OPTN"} {"GO.ID":"GO:2000241","Term":"regulation of reproductive process","Annotated":139,"Significant":8,"Expected":8.39,"Rank in p.value_classic":3369,"p.value_elim":0.60451,"p.value_classic":0.60741,"genes":"CDC25A,DAZL,HORMAD1,NPM2,OVOL1,PKMYT1,PLB1,ZWINT"} {"GO.ID":"GO:0051246","Term":"regulation of protein metabolic process","Annotated":1842,"Significant":124,"Expected":111.25,"Rank in p.value_classic":1392,"p.value_elim":0.60512,"p.value_classic":0.09926,"genes":"ADAM8,AGT,AIM2,AMER1,ATP13A2,BANK1,C3,CARD16,CCL5,CCNA2,CCNE2,CCNF,CD28,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDKN2C,CEACAM1,CHAC1,CLEC6A,CLSPN,CSF1,CTSL,CTSS,CX3CR1,DAB2,DAZL,DEPTOR,DHFR,DTL,DTNBP1,DTX3L,EDN1,ENPP2,EPAS1,FAM107A,FAM20A,FAS,FAXDC2,GRAMD4,GSAP,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,JAK2,JAK3,KITLG,KLF4,LAMP3,LILRA2,LIMK2,LRP5,LRRK2,LYN,MAD2L1,MEFV,MIR503,MMD,MMP9,MVP,NCF1,NECAB2,NLRP12,NMI,NOD2,NRP1,NUB1,OSM,P2RX7,PARP10,PARP14,PARP9,PID1,PIWIL4,PKIB,PKMYT1,PMAIP1,PML,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RHOBTB3,RIPK2,S100A10,SAMD4A,SEPTIN4,SERPING1,SLC11A1,SOAT1,SOCS1,SOX17,SPTBN4,STAT2,SUCNR1,TANK,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TRABD2A,TSPAN15,TYMS,UHRF1,VEGFC,WARS1,XRN1,ZC3H12A"} {"GO.ID":"GO:0001946","Term":"lymphangiogenesis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3309,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"VEGFC"} {"GO.ID":"GO:1904923","Term":"regulation of autophagy of mitochondrion in response to mitochondrial depolarization","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3310,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"OPTN"} {"GO.ID":"GO:0045618","Term":"positive regulation of keratinocyte differentiation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3311,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"PLAAT4"} {"GO.ID":"GO:1903909","Term":"regulation of receptor clustering","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3312,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"TNFAIP6"} {"GO.ID":"GO:0070193","Term":"synaptonemal complex organization","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3313,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"HORMAD1"} {"GO.ID":"GO:0000272","Term":"polysaccharide catabolic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3314,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"G6PC1"} {"GO.ID":"GO:0030730","Term":"sequestering of triglyceride","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3315,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"LPL"} {"GO.ID":"GO:2000095","Term":"regulation of Wnt signaling pathway, planar cell polarity pathway","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3316,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DAB2"} {"GO.ID":"GO:0006978","Term":"DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3317,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"PYHIN1"} {"GO.ID":"GO:2000052","Term":"positive regulation of non-canonical Wnt signaling pathway","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3318,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DAB2"} {"GO.ID":"GO:1905564","Term":"positive regulation of vascular endothelial cell proliferation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3319,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"GHRL"} {"GO.ID":"GO:0030813","Term":"positive regulation of nucleotide catabolic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3320,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"P2RX7"} {"GO.ID":"GO:0090737","Term":"telomere maintenance via telomere trimming","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3321,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"EXO1"} {"GO.ID":"GO:0072087","Term":"renal vesicle development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3322,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"STAT1"} {"GO.ID":"GO:0003352","Term":"regulation of cilium movement","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3323,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DNAAF1"} {"GO.ID":"GO:0051014","Term":"actin filament severing","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3324,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"SCIN"} {"GO.ID":"GO:0051044","Term":"positive regulation of membrane protein ectodomain proteolysis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3325,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"ADAM8"} {"GO.ID":"GO:0050862","Term":"positive regulation of T cell receptor signaling pathway","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3326,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CYLD"} {"GO.ID":"GO:0150118","Term":"negative regulation of cell-substrate junction organization","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3327,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"FAM107A"} {"GO.ID":"GO:0097094","Term":"craniofacial suture morphogenesis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3328,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"TIFAB"} {"GO.ID":"GO:0002323","Term":"natural killer cell activation involved in immune response","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3329,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"HLA-F"} {"GO.ID":"GO:0033123","Term":"positive regulation of purine nucleotide catabolic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3330,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"P2RX7"} {"GO.ID":"GO:2000369","Term":"regulation of clathrin-dependent endocytosis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3331,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DAB2"} {"GO.ID":"GO:0043116","Term":"negative regulation of vascular permeability","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3332,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CEACAM1"} {"GO.ID":"GO:0090656","Term":"t-circle formation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3333,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"EXO1"} {"GO.ID":"GO:0044790","Term":"suppression of viral release by host","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3334,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"PML"} {"GO.ID":"GO:0001325","Term":"formation of extrachromosomal circular DNA","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3335,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"EXO1"} {"GO.ID":"GO:0048313","Term":"Golgi inheritance","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3336,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CDK1"} {"GO.ID":"GO:0050687","Term":"negative regulation of defense response to virus","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3337,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"FGL2"} {"GO.ID":"GO:0048308","Term":"organelle inheritance","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3338,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CDK1"} {"GO.ID":"GO:0060644","Term":"mammary gland epithelial cell differentiation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3339,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"LBH"} {"GO.ID":"GO:0055064","Term":"chloride ion homeostasis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3340,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"SLC12A3"} {"GO.ID":"GO:0032717","Term":"negative regulation of interleukin-8 production","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3341,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"KLF4"} {"GO.ID":"GO:0043518","Term":"negative regulation of DNA damage response, signal transduction by p53 class mediator","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3342,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CD74"} {"GO.ID":"GO:2000725","Term":"regulation of cardiac muscle cell differentiation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3343,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DLL1"} {"GO.ID":"GO:0072234","Term":"metanephric nephron tubule development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3344,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"STAT1"} {"GO.ID":"GO:0051299","Term":"centrosome separation","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3345,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"KIF11"} {"GO.ID":"GO:0035338","Term":"long-chain fatty-acyl-CoA biosynthetic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3346,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"ACSL1"} {"GO.ID":"GO:1903140","Term":"regulation of establishment of endothelial barrier","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3347,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CDH5"} {"GO.ID":"GO:0021854","Term":"hypothalamus development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3348,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"NRP1"} {"GO.ID":"GO:2001034","Term":"positive regulation of double-strand break repair via nonhomologous end joining","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3349,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"PARP3"} {"GO.ID":"GO:1904754","Term":"positive regulation of vascular associated smooth muscle cell migration","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3350,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"NR4A3"} {"GO.ID":"GO:1902170","Term":"cellular response to reactive nitrogen species","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3351,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CCNA2"} {"GO.ID":"GO:0016202","Term":"regulation of striated muscle tissue development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3352,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CENPF"} {"GO.ID":"GO:0098712","Term":"L-glutamate import across plasma membrane","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3353,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"KCNJ10"} {"GO.ID":"GO:0051895","Term":"negative regulation of focal adhesion assembly","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3354,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"FAM107A"} {"GO.ID":"GO:0021692","Term":"cerebellar Purkinje cell layer morphogenesis","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3355,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"DLL1"} {"GO.ID":"GO:0009048","Term":"dosage compensation by inactivation of X chromosome","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3356,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"BRCA1"} {"GO.ID":"GO:0045217","Term":"cell-cell junction maintenance","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3357,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"MTSS1"} {"GO.ID":"GO:1903599","Term":"positive regulation of autophagy of mitochondrion","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3358,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"NOD2"} {"GO.ID":"GO:0061548","Term":"ganglion development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3359,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"NRP1"} {"GO.ID":"GO:0061684","Term":"chaperone-mediated autophagy","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3360,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"ATP13A2"} {"GO.ID":"GO:0006855","Term":"xenobiotic transmembrane transport","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3361,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"ATP8B1"} {"GO.ID":"GO:0071625","Term":"vocalization behavior","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3362,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"TIFAB"} {"GO.ID":"GO:0015802","Term":"basic amino acid transport","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3363,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"SLC11A1"} {"GO.ID":"GO:0006837","Term":"serotonin transport","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3364,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"SLC18A1"} {"GO.ID":"GO:0009310","Term":"amine catabolic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3365,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"SAT1"} {"GO.ID":"GO:0045821","Term":"positive regulation of glycolytic process","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3366,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"P2RX7"} {"GO.ID":"GO:1901550","Term":"regulation of endothelial cell development","Annotated":15,"Significant":1,"Expected":0.91,"Rank in p.value_classic":3367,"p.value_elim":0.60644,"p.value_classic":0.6074,"genes":"CDH5"} {"GO.ID":"GO:0009165","Term":"nucleotide biosynthetic process","Annotated":260,"Significant":15,"Expected":15.7,"Rank in p.value_classic":3370,"p.value_elim":0.60714,"p.value_classic":0.61111,"genes":"ACSL1,AK1,CMPK2,IDO1,IDO2,KARS1,NPR1,PARP10,PARP9,PDK4,PID1,RRM2,SLC4A7,TYMS,VPS9D1"} {"GO.ID":"GO:1901136","Term":"carbohydrate derivative catabolic process","Annotated":226,"Significant":13,"Expected":13.65,"Rank in p.value_classic":3371,"p.value_elim":0.60931,"p.value_classic":0.613,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CTSL,DPYS,ENPP4,FBXO6,LYVE1,P2RX7,PDE4B,SLC2A6,TYMP,UNG"} {"GO.ID":"GO:0140029","Term":"exocytic process","Annotated":70,"Significant":8,"Expected":4.23,"Rank in p.value_classic":1179,"p.value_elim":0.61042,"p.value_classic":0.05935,"genes":"ERC2,LYN,PLEK,PRRT2,RALB,STX11,STX1A,SYT1"} {"GO.ID":"GO:0003006","Term":"developmental process involved in reproduction","Annotated":669,"Significant":39,"Expected":40.4,"Rank in p.value_classic":3377,"p.value_elim":0.61043,"p.value_classic":0.6169,"genes":"ADGB,BCL2L11,BCL6,C3,CSF1,DAZL,DMC1,E2F8,EDN1,GHRL,HESX1,HORMAD1,IGF2R,KITLG,LIMK2,LRRK2,MERTK,NPM2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PROK2,RHOBTB3,SEPTIN4,SGPL1,SOX17,SPATA9,SSTR2,SYNE1,TBATA,TDRD9,TIFAB,TMEM119,TNFAIP6,TNFSF10,TYRO3,ZMYND15"} {"GO.ID":"GO:0031623","Term":"receptor internalization","Annotated":105,"Significant":6,"Expected":6.34,"Rank in p.value_classic":3372,"p.value_elim":0.61213,"p.value_classic":0.61462,"genes":"CEACAM1,DNM1,DTNBP1,NECAB2,RALB,SYNE1"} {"GO.ID":"GO:0038061","Term":"non-canonical NF-kappaB signal transduction","Annotated":109,"Significant":11,"Expected":6.58,"Rank in p.value_classic":1207,"p.value_elim":0.61266,"p.value_classic":0.0646,"genes":"CYLD,EDA,EDN1,IFI35,LITAF,NLRP12,NMI,NOD2,RELB,TLR7,ZC3H12A"} {"GO.ID":"GO:0022414","Term":"reproductive process","Annotated":1010,"Significant":71,"Expected":61,"Rank in p.value_classic":1380,"p.value_elim":0.61296,"p.value_classic":0.09757,"genes":"ACOD1,ADGB,ANTXR1,APOL2,BCL2L11,BCL6,C3,CCNE2,CD38,CDC25A,CDK1,CLIC5,CRHBP,CSF1,CXADR,CYP1A1,DAZL,DMC1,E2F8,EDN1,EME1,EXO1,GHRL,HESX1,HORMAD1,IDO1,IGF2R,KITLG,LIMK2,LRRK2,MAFF,MEIKIN,MERTK,MMP9,NCAPH,NDC80,NPM2,NUF2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PKMYT1,PLB1,PROK2,PZP,RAD54B,RAD54L,RHOBTB3,RXFP1,SEPTIN4,SGPL1,SOX17,SPATA9,SPTBN4,SSTR2,SYNE1,SYT6,TBATA,TDRD9,THBD,TIFAB,TMEM119,TNFAIP6,TNFSF10,TOP2A,TYRO3,XRCC2,ZMYND15,ZWINT"} {"GO.ID":"GO:0120035","Term":"regulation of plasma membrane bounded cell projection organization","Annotated":568,"Significant":33,"Expected":34.3,"Rank in p.value_classic":3395,"p.value_elim":0.61318,"p.value_classic":0.61911,"genes":"ANLN,ATP1B2,ATP8B1,B2M,CD38,CDKL1,CYLD,DAB1,DAB2,DTNBP1,ENPP2,EPHB3,FSCN1,FSTL4,ICAM1,IL15RA,KIF26A,KLF4,KREMEN1,LIMK2,LRRK2,LYN,NRCAM,NRP1,P2RX7,PLXNA2,RAPGEF2,RTN4RL1,SCARF1,SDC2,SEMA6B,STAP1,SYNE1"} {"GO.ID":"GO:0010975","Term":"regulation of neuron projection development","Annotated":398,"Significant":23,"Expected":24.04,"Rank in p.value_classic":3394,"p.value_elim":0.61369,"p.value_classic":0.61861,"genes":"ATP1B2,B2M,CD38,DAB1,DAB2,DTNBP1,EPHB3,FSTL4,IL15RA,KIF26A,KLF4,KREMEN1,LRRK2,LYN,NRCAM,NRP1,PLXNA2,RAPGEF2,RTN4RL1,SCARF1,SDC2,SEMA6B,SYNE1"} {"GO.ID":"GO:0010761","Term":"fibroblast migration","Annotated":52,"Significant":3,"Expected":3.14,"Rank in p.value_classic":3373,"p.value_elim":0.61387,"p.value_classic":0.61562,"genes":"APPL2,PML,SGPL1"} {"GO.ID":"GO:0002042","Term":"cell migration involved in sprouting angiogenesis","Annotated":52,"Significant":3,"Expected":3.14,"Rank in p.value_classic":3374,"p.value_elim":0.61387,"p.value_classic":0.61562,"genes":"KLF4,MIR503,NRP1"} {"GO.ID":"GO:0051148","Term":"negative regulation of muscle cell differentiation","Annotated":52,"Significant":3,"Expected":3.14,"Rank in p.value_classic":3375,"p.value_elim":0.61387,"p.value_classic":0.61562,"genes":"BHLHE41,DLL1,TMEM119"} {"GO.ID":"GO:0006473","Term":"protein acetylation","Annotated":52,"Significant":3,"Expected":3.14,"Rank in p.value_classic":3376,"p.value_elim":0.61387,"p.value_classic":0.61562,"genes":"DSCC1,ESCO2,PML"} {"GO.ID":"GO:0007049","Term":"cell cycle","Annotated":1569,"Significant":125,"Expected":94.76,"Rank in p.value_classic":457,"p.value_elim":0.61401,"p.value_classic":0.00059,"genes":"ABCB1,ANLN,APPL2,ATF5,AURKB,BCL2L11,BCL6,BIRC5,BRCA1,BTN2A2,BUB1B,CCNA2,CCNE2,CCNF,CD28,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDK1,CDKL1,CDKN2C,CDT1,CENPF,CENPK,CENPM,CENPU,CHAF1B,CHMP4C,CHTF18,CLSPN,CYLD,CYP1A1,DAZL,DMC1,DSCC1,DTL,DTX3L,DYNLT1,E2F1,E2F2,E2F8,EDN1,EME1,EML4,ERCC6L,ESCO2,EXO1,FAM107A,FBXO6,FEN1,GADD45B,GINS1,GTSE1,HELLS,HGF,HJURP,HLA-G,HORMAD1,IQGAP3,IRF1,JADE2,KIF11,KIF15,KIF18B,KIF23,KLF4,LIMK2,LRP5,MAD2L1,MCM2,MCM4,MCM5,MCM6,MCM7,MEIKIN,MIR503,MKI67,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NDC80,NPM2,NUF2,NUSAP1,OIP5,ORC1,OVOL1,PARP3,PARP9,PCLAF,PIM1,PIWIL4,PKMYT1,PLSCR1,PML,PRC1,PSME1,PSME2,PYHIN1,RAD54B,RAD54L,RALB,RMI2,RRM2,SEPTIN4,SPC24,SPC25,STMN1,TACC2,TAL1,TDRD9,TICRR,TK1,TOP2A,UBD,UHRF1,WDR62,WDR76,WEE1,XRCC2,ZWINT"} {"GO.ID":"GO:0008154","Term":"actin polymerization or depolymerization","Annotated":175,"Significant":10,"Expected":10.57,"Rank in p.value_classic":3393,"p.value_elim":0.61469,"p.value_classic":0.61792,"genes":"FAM107A,GHRL,JAK2,MICAL2,MSRB1,PLEK,PSTPIP2,SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0043406","Term":"positive regulation of MAP kinase activity","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3387,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"CD40,EDN1,LRRK2,TNFRSF11A"} {"GO.ID":"GO:0032206","Term":"positive regulation of telomere maintenance","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3388,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"AURKB,GCH1,PKIB,PML"} {"GO.ID":"GO:0055006","Term":"cardiac cell development","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3389,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"ASB2,CDK1,CXADR,EDN1"} {"GO.ID":"GO:0014909","Term":"smooth muscle cell migration","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3390,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"CCL5,MIR503,NR4A3,NRP1"} {"GO.ID":"GO:0006278","Term":"RNA-templated DNA biosynthetic process","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3391,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"AURKB,GCH1,PKIB,XRN1"} {"GO.ID":"GO:0042982","Term":"amyloid precursor protein metabolic process","Annotated":70,"Significant":4,"Expected":4.23,"Rank in p.value_classic":3392,"p.value_elim":0.61531,"p.value_classic":0.61734,"genes":"GSAP,LYN,NECAB2,SOAT1"} {"GO.ID":"GO:0071216","Term":"cellular response to biotic stimulus","Annotated":217,"Significant":35,"Expected":13.11,"Rank in p.value_classic":179,"p.value_elim":0.61575,"p.value_classic":8.7e-08,"genes":"ACOD1,CARD16,CASP7,CD274,CD40,CD80,CMPK2,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,EME1,GBP2,GBP3,GBP5,JAK2,KLRK1,LILRA2,LITAF,LYN,MMP9,NOD2,PDCD1LG2,PDE4B,PLSCR4,PPM1E,RIPK2,SBNO2,SCIMP,STAP1,TICAM2,TIFAB,TLR10,ZC3H12A"} {"GO.ID":"GO:1901616","Term":"organic hydroxy compound catabolic process","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3378,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"GK,SCARF1"} {"GO.ID":"GO:0070316","Term":"regulation of G0 to G1 transition","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3379,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"HLA-G,MIR503"} {"GO.ID":"GO:0043388","Term":"positive regulation of DNA binding","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3380,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"MMP9,PYHIN1"} {"GO.ID":"GO:0007035","Term":"vacuolar acidification","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3381,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"ATP6V0D2,SLC11A1"} {"GO.ID":"GO:0071425","Term":"hematopoietic stem cell proliferation","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3382,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"KITLG,PIM1"} {"GO.ID":"GO:0051180","Term":"vitamin transport","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3383,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"ABCG2,SLC2A6"} {"GO.ID":"GO:0046466","Term":"membrane lipid catabolic process","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3384,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"ENPP2,SGPL1"} {"GO.ID":"GO:0048846","Term":"axon extension involved in axon guidance","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3385,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"NRP1,SEMA6B"} {"GO.ID":"GO:1902284","Term":"neuron projection extension involved in neuron projection guidance","Annotated":34,"Significant":2,"Expected":2.05,"Rank in p.value_classic":3386,"p.value_elim":0.61585,"p.value_classic":0.61726,"genes":"NRP1,SEMA6B"} {"GO.ID":"GO:0046328","Term":"regulation of JNK cascade","Annotated":123,"Significant":7,"Expected":7.43,"Rank in p.value_classic":3396,"p.value_elim":0.61645,"p.value_classic":0.61914,"genes":"CYLD,GADD45B,NCF1,NOD2,NRK,RIPK2,SLAMF1"} {"GO.ID":"GO:0043271","Term":"negative regulation of monoatomic ion transport","Annotated":88,"Significant":5,"Expected":5.31,"Rank in p.value_classic":3397,"p.value_elim":0.61807,"p.value_classic":0.62034,"genes":"CAMK2D,KCNE5,MMP9,SRI,TRDN"} {"GO.ID":"GO:0051261","Term":"protein depolymerization","Annotated":106,"Significant":6,"Expected":6.4,"Rank in p.value_classic":3399,"p.value_elim":0.6214,"p.value_classic":0.62389,"genes":"KIF18B,MICAL2,PLEK,SCIN,SPTBN4,STMN1"} {"GO.ID":"GO:0048729","Term":"tissue morphogenesis","Annotated":502,"Significant":29,"Expected":30.32,"Rank in p.value_classic":3400,"p.value_elim":0.62165,"p.value_classic":0.62717,"genes":"AGT,ASB2,CEACAM1,CELSR1,CSF1,CTNS,CXCL10,DLL1,DNAAF1,EDN1,GCNT3,HBEGF,HESX1,HGF,IFT122,ITGB5,KLF4,LRP5,MICAL2,MTSS1,NRP1,PML,PRKX,S1PR1,SOX17,STAT1,TAL1,TGM2,VEGFC"} {"GO.ID":"GO:0006796","Term":"phosphate-containing compound metabolic process","Annotated":2155,"Significant":145,"Expected":130.15,"Rank in p.value_classic":1281,"p.value_elim":0.62171,"p.value_classic":0.07923,"genes":"AATK,ACOT4,ACSL1,AGT,AK1,ATP13A2,AURKB,BANK1,BIRC5,BUB1B,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CEACAM1,CIITA,CISH,CLEC6A,CLSPN,CMPK2,CSF1,CTNS,CX3CR1,DAB2,DAPP1,DEPTOR,DGAT2,DPYS,DTNBP1,EDN1,ENPP2,EPHB3,FAM20A,FAS,FAXDC2,G6PC1,GIMAP7,GK,GTPBP1,HBEGF,HGF,HLA-DRB1,IDO1,IDO2,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JAK2,JAK3,KARS1,KITLG,LCLAT1,LIMK2,LMTK2,LPL,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NAAA,NCF1,NLRC5,NLRP12,NOD2,NPR1,NRK,NRP1,OSM,P2RX7,PARP10,PARP14,PARP9,PCYT1A,PDE4B,PDK4,PID1,PIM1,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PNPLA3,PPA1,PPM1E,PRKX,PTPRU,RALB,RAPGEF2,RIPK2,RRM2,SERINC5,SLAMF8,SLC11A1,SLC20A1,SLC2A6,SLC4A7,SOCS1,SPTBN4,STAP1,STAT2,TK1,TLR7,TLR8,TMEM119,TMEM150A,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFSF18,TYMP,TYMS,TYRO3,UNG,VEGFC,VPS9D1,VRK2,WARS1,WEE1,ZC3H12A"} {"GO.ID":"GO:0001913","Term":"T cell mediated cytotoxicity","Annotated":49,"Significant":16,"Expected":2.96,"Rank in p.value_classic":153,"p.value_elim":0.62385,"p.value_classic":1.4e-08,"genes":"B2M,CD1A,CD1C,CEACAM1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,P2RX7,TAP2"} {"GO.ID":"GO:0030902","Term":"hindbrain development","Annotated":124,"Significant":7,"Expected":7.49,"Rank in p.value_classic":3401,"p.value_elim":0.625,"p.value_classic":0.62769,"genes":"ATF5,ATP1B2,DAB1,DLL1,EGR2,PLXNA2,SSTR2"} {"GO.ID":"GO:0030198","Term":"extracellular matrix organization","Annotated":263,"Significant":15,"Expected":15.88,"Rank in p.value_classic":3407,"p.value_elim":0.62504,"p.value_classic":0.62898,"genes":"ADAM8,ADAMTS15,AGT,ANTXR1,COL23A1,COL9A2,COLGALT2,COLQ,COMP,CTSS,FSCN1,MMP25,MMP9,OLFML2B,RXFP1"} {"GO.ID":"GO:1901700","Term":"response to oxygen-containing compound","Annotated":1303,"Significant":111,"Expected":78.7,"Rank in p.value_classic":360,"p.value_elim":0.62593,"p.value_classic":0.0001,"genes":"ACOD1,ACSL1,AGT,ALAS1,APPL2,BRCA1,C2,CARD16,CASP4,CASP7,CASTOR1,CCL7,CCNA2,CD274,CD38,CD40,CD80,CDC6,CDK1,CDT1,CEACAM1,CMPK2,COLEC12,CRHBP,CSF2RB,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYP1A1,DGAT2,DHFR,DTNBP1,EDN1,EGR2,GBP2,GBP3,GBP5,GCH1,GHRL,GJD3,GLUL,GNG2,GRAMD1B,GRIN3A,HGF,HLA-DRB1,ICAM1,IDO1,IGF2R,IL12A,IL12RB2,IL18BP,JAK2,JAK3,KLF4,KLRK1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MMP9,NCF1,NOD2,NR4A3,P2RX4,P2RX7,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PLSCR4,PNPLA3,POLB,PPM1E,PTGER4,PXN,RAPGEF2,RIPK2,SBNO2,SCIMP,SESN3,SIDT2,SLC11A1,SLC12A3,SLC2A5,SOCS1,SRI,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,TESC,TGM2,THBD,TICAM2,TIFAB,TLR7,TNFRSF11A,TNFSF10,TYMS,VCAM1,XRN1,ZC3H12A"} {"GO.ID":"GO:0051128","Term":"regulation of cellular component organization","Annotated":2115,"Significant":144,"Expected":127.74,"Rank in p.value_classic":1180,"p.value_elim":0.62635,"p.value_classic":0.05964,"genes":"AGT,ANLN,ANTXR1,APPL2,ATF5,ATP13A2,ATP1B2,ATP8B1,AURKB,B2M,BAZ1A,BCL2L11,BCL6,BIRC5,BRCA1,BUB1B,C2,C3,C4A,C4B,CALCOCO2,CAMK2D,CASP7,CCNF,CD28,CD300LF,CD38,CDC6,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CELSR1,CENPF,CHMP4C,CISH,COLQ,CTTNBP2,CXCL10,CXCL9,CYLD,DAB1,DAB2,DAZL,DLL1,DTNBP1,DYSF,EDN1,ENPP2,EPHB3,ERC2,FAM107A,FCN1,FEN1,FSCN1,FSTL4,GBP2,GBP5,GCH1,GHRL,HBEGF,HGF,HJURP,HORMAD1,ICAM1,IL15,IL15RA,JADE2,KIF26A,KLF4,KREMEN1,LIMK2,LRP5,LRRK2,LYN,MAD2L1,MDGA1,MEFV,MERTK,MKI67,MMP9,MTSS1,NCAPG,NCAPG2,NCAPH,NDC80,NECAB2,NOD2,NPM2,NPR1,NRCAM,NRP1,NUF2,NUSAP1,P2RX7,PARP3,PID1,PKIB,PKMYT1,PLEK,PLSCR1,PLXNA2,PMAIP1,PML,PPM1E,PRRT2,PTGER4,PXN,RALB,RAPGEF2,RMI2,RTN4RL1,S100A10,S1PR1,SCARF1,SCIN,SDC2,SEMA6B,SLAMF1,SLC11A1,SOX17,SPC24,SPC25,SPTBN4,STAP1,STAT2,STMN1,STX1A,SYNE1,SYT1,TAL1,TGM2,THBS2,TMSB10,TNFSF10,TOP2A,TRABD2A,TRIM31,USP6NL,WARS1,WDR62,XRN1,ZWINT"} {"GO.ID":"GO:0030968","Term":"endoplasmic reticulum unfolded protein response","Annotated":71,"Significant":4,"Expected":4.29,"Rank in p.value_classic":3402,"p.value_elim":0.62656,"p.value_classic":0.62858,"genes":"AGR2,ATF3,BCL2L11,DERL3"} {"GO.ID":"GO:0033559","Term":"unsaturated fatty acid metabolic process","Annotated":71,"Significant":4,"Expected":4.29,"Rank in p.value_classic":3403,"p.value_elim":0.62656,"p.value_classic":0.62858,"genes":"CD74,CYP1A1,EDN1,EPHX1"} {"GO.ID":"GO:0042306","Term":"regulation of protein import into nucleus","Annotated":53,"Significant":3,"Expected":3.2,"Rank in p.value_classic":3404,"p.value_elim":0.62686,"p.value_classic":0.62861,"genes":"CDK1,JAK2,ZC3H12A"} {"GO.ID":"GO:0042698","Term":"ovulation cycle","Annotated":53,"Significant":3,"Expected":3.2,"Rank in p.value_classic":3405,"p.value_elim":0.62686,"p.value_classic":0.62861,"genes":"SGPL1,TNFAIP6,TYRO3"} {"GO.ID":"GO:0048857","Term":"neural nucleus development","Annotated":53,"Significant":3,"Expected":3.2,"Rank in p.value_classic":3406,"p.value_elim":0.62686,"p.value_classic":0.62861,"genes":"INA,PADI2,SYNGR3"} {"GO.ID":"GO:2000145","Term":"regulation of cell motility","Annotated":835,"Significant":67,"Expected":50.43,"Rank in p.value_classic":746,"p.value_elim":0.62703,"p.value_classic":0.00985,"genes":"ADAM8,ADORA3,AGT,AMOT,APPL2,ASCL2,ATP1B2,BCL6,CCL5,CCL7,CCL8,CD274,CD40,CD74,CDH5,CEACAM1,CHRD,CSF1,CX3CR1,CXCL10,CXCR3,DAB2,EDN1,ENPP2,FAM107A,GLIPR2,GLUL,GPR183,HBEGF,HGF,ICAM1,IFITM1,IL12A,JAK2,KIF26A,KITLG,KLF4,KLRK1,LYN,LYVE1,MIR503,MMP9,MTUS1,NOD2,NR4A3,NRP1,ONECUT2,P2RX4,PADI2,PLXNA2,PRKX,PTGER4,PTPRU,RAPGEF2,S1PR1,SEMA6B,SLAMF1,SLAMF8,STAP1,STMN1,TMSB10,TNFAIP6,TNFRSF14,TNFSF18,VEGFC,WDR62,ZC3H12A"} {"GO.ID":"GO:0042542","Term":"response to hydrogen peroxide","Annotated":89,"Significant":5,"Expected":5.38,"Rank in p.value_classic":3408,"p.value_elim":0.62811,"p.value_classic":0.63037,"genes":"CDK1,EDN1,IL18BP,KLF4,STAT1"} {"GO.ID":"GO:0009394","Term":"2'-deoxyribonucleotide metabolic process","Annotated":38,"Significant":6,"Expected":2.3,"Rank in p.value_classic":927,"p.value_elim":0.6284,"p.value_classic":0.02511,"genes":"CMPK2,DPYS,RRM2,TYMP,TYMS,UNG"} {"GO.ID":"GO:1903320","Term":"regulation of protein modification by small protein conjugation or removal","Annotated":229,"Significant":13,"Expected":13.83,"Rank in p.value_classic":3446,"p.value_elim":0.62841,"p.value_classic":0.63207,"genes":"AMER1,DTX3L,EPAS1,FAM107A,LRRK2,MAD2L1,NMI,NOD2,PARP10,RIPK2,SEPTIN4,TANK,ZC3H12A"} {"GO.ID":"GO:0072359","Term":"circulatory system development","Annotated":951,"Significant":62,"Expected":57.44,"Rank in p.value_classic":2165,"p.value_elim":0.62846,"p.value_classic":0.27886,"genes":"ADAM8,AMOT,ANK2,ANTXR1,ASB2,BRCA1,C3,CASP7,CD40,CDH5,CDK1,CEACAM1,COMP,CX3CR1,CXADR,CXCL10,CXCR3,CYSLTR1,DHRS3,DLL1,DNAAF1,E2F2,E2F8,EDN1,EGR2,EPAS1,EPHB3,GHRL,GLUL,HLA-G,IFT122,IL12A,KLF4,LRP5,MICAL2,MIR503,NPR1,NRCAM,NRP1,PDE3B,PIM1,PLCD3,PML,PRKX,PROK2,RAPGEF2,RNF213,S1PR1,SAT1,SGPL1,SOX17,SRI,STAT1,SYNE1,TAL1,THBS2,TNFAIP2,TYMP,VCAM1,VEGFC,WARS1,ZC3H12A"} {"GO.ID":"GO:0051494","Term":"negative regulation of cytoskeleton organization","Annotated":142,"Significant":8,"Expected":8.58,"Rank in p.value_classic":3445,"p.value_elim":0.62871,"p.value_classic":0.63158,"genes":"BRCA1,CCNF,CDH5,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0050922","Term":"negative regulation of chemotaxis","Annotated":53,"Significant":7,"Expected":3.2,"Rank in p.value_classic":1051,"p.value_elim":0.62897,"p.value_classic":0.03911,"genes":"KLRK1,NRP1,PADI2,SEMA6B,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0001763","Term":"morphogenesis of a branching structure","Annotated":177,"Significant":10,"Expected":10.69,"Rank in p.value_classic":3447,"p.value_elim":0.62908,"p.value_classic":0.63228,"genes":"AGT,CELSR1,CSF1,EDN1,HGF,LRP5,LRRK2,NRP1,PML,TGM2"} {"GO.ID":"GO:0010155","Term":"regulation of proton transport","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3409,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"TESC"} {"GO.ID":"GO:0090190","Term":"positive regulation of branching involved in ureteric bud morphogenesis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3410,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"AGT"} {"GO.ID":"GO:0060438","Term":"trachea development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3411,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"EDA"} {"GO.ID":"GO:0010755","Term":"regulation of plasminogen activation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3412,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"S100A10"} {"GO.ID":"GO:0006991","Term":"response to sterol depletion","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3413,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"LYN"} {"GO.ID":"GO:0010893","Term":"positive regulation of steroid biosynthetic process","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3414,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"DAB2"} {"GO.ID":"GO:0035902","Term":"response to immobilization stress","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3415,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"CYP1A1"} {"GO.ID":"GO:1904044","Term":"response to aldosterone","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3416,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"SLC12A3"} {"GO.ID":"GO:0010623","Term":"programmed cell death involved in cell development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3417,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"KITLG"} {"GO.ID":"GO:0050872","Term":"white fat cell differentiation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3418,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"PNPLA3"} {"GO.ID":"GO:0033151","Term":"V(D)J recombination","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3419,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"POLB"} {"GO.ID":"GO:0003417","Term":"growth plate cartilage development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3420,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"COMP"} {"GO.ID":"GO:0003159","Term":"morphogenesis of an endothelium","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3421,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"CXCL10"} {"GO.ID":"GO:1902036","Term":"regulation of hematopoietic stem cell differentiation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3422,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"OSM"} {"GO.ID":"GO:1902001","Term":"fatty acid transmembrane transport","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3423,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"ACSL1"} {"GO.ID":"GO:1901096","Term":"regulation of autophagosome maturation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3424,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"CALCOCO2"} {"GO.ID":"GO:0048485","Term":"sympathetic nervous system development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3425,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"NRP1"} {"GO.ID":"GO:1903358","Term":"regulation of Golgi organization","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3426,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"USP6NL"} {"GO.ID":"GO:0002283","Term":"neutrophil activation involved in immune response","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3427,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"LILRA2"} {"GO.ID":"GO:0038166","Term":"angiotensin-activated signaling pathway","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3428,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"AGT"} {"GO.ID":"GO:0055081","Term":"monoatomic anion homeostasis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3429,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"SLC12A3"} {"GO.ID":"GO:0072189","Term":"ureter development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3430,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"SOX17"} {"GO.ID":"GO:0042772","Term":"DNA damage response, signal transduction resulting in transcription","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3431,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"PYHIN1"} {"GO.ID":"GO:0044539","Term":"long-chain fatty acid import into cell","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3432,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"ACSL1"} {"GO.ID":"GO:1903429","Term":"regulation of cell maturation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3433,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"LRRK2"} {"GO.ID":"GO:0061154","Term":"endothelial tube morphogenesis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3434,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"CXCL10"} {"GO.ID":"GO:0072243","Term":"metanephric nephron epithelium development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3435,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"STAT1"} {"GO.ID":"GO:2000738","Term":"positive regulation of stem cell differentiation","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3436,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"SOX17"} {"GO.ID":"GO:0060977","Term":"coronary vasculature morphogenesis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3437,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"NRP1"} {"GO.ID":"GO:0007176","Term":"regulation of epidermal growth factor-activated receptor activity","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3438,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"NCF1"} {"GO.ID":"GO:0097186","Term":"amelogenesis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3439,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"FAM20A"} {"GO.ID":"GO:2000811","Term":"negative regulation of anoikis","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3440,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"PDK4"} {"GO.ID":"GO:0031573","Term":"mitotic intra-S DNA damage checkpoint signaling","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3441,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"EME1"} {"GO.ID":"GO:0090036","Term":"regulation of protein kinase C signaling","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3442,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"CD40"} {"GO.ID":"GO:1903541","Term":"regulation of exosomal secretion","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3443,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"ATP13A2"} {"GO.ID":"GO:1901863","Term":"positive regulation of muscle tissue development","Annotated":16,"Significant":1,"Expected":0.97,"Rank in p.value_classic":3444,"p.value_elim":0.63018,"p.value_classic":0.63114,"genes":"DLL1"} {"GO.ID":"GO:0008150","Term":"biological_process","Annotated":13083,"Significant":789,"Expected":790.15,"Rank in p.value_classic":4674,"p.value_elim":0.63025,"p.value_classic":0.95152,"genes":"AATK,ABCB1,ABCC11,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AK1,AKAP7,ALAS1,AMER1,AMOT,ANK2,ANKH,ANLN,ANO4,ANTXR1,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARAP2,ARL4C,ARMT1,ASB2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL2A1,BCL2L11,BCL2L14,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C15orf48,C1QB,C1QTNF5,C1R,C1RL,C1S,C2,C21orf91,C3,C3orf38,C3orf70,C4A,C4B,CA11,CACNA2D3,CADPS2,CALCOCO2,CALHM6,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CBLN3,CBR3,CCDC170,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CCRL2,CD101,CD163,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD69,CD7,CD74,CD80,CD83,CD93,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CENPK,CENPM,CENPU,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHRD,CHTF18,CIBAR1,CIITA,CISH,CLEC10A,CLEC6A,CLEC9A,CLIC5,CLSPN,CMPK2,CNDP2,COL23A1,COL9A2,COLEC12,COLGALT2,COLQ,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTRL,CTSL,CTSO,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DAZL,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DMC1,DNAAF1,DNM1,DNPEP,DOP1A,DPYS,DRAM1,DSCC1,DSE,DTL,DTNBP1,DTX3L,DYNLT1,DYNLT5,DYSF,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,EML4,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ERC2,ERCC6L,ESCO2,ETV7,EXO1,EXOC3L1,EXOC3L4,F2RL3,FAM107A,FAM111B,FAM13A,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,FGD5,FGL1,FGL2,FLT3LG,FLVCR2,FMNL2,FRMD3,FSCN1,FSTL4,FYB1,G0S2,G6PC1,GABRA3,GADD45B,GAL3ST4,GALNT18,GAREM1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GCNT3,GFRA2,GGT5,GHRL,GIMAP7,GIMAP8,GINS1,GINS2,GJD3,GK,GLDN,GLIPR2,GLUL,GNG2,GOLM1,GPR183,GPR31,GRAMD1B,GRAMD4,GRIN3A,GRM8,GSAP,GSDMA,GSDMD,GSTK1,GTPBP1,GTSE1,H2BC21,HAPLN3,HAVCR1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HIVEP2,HJURP,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSD11B1,HSD3B7,HSH2D,HTRA1,HYI,ICAM1,ICAM2,IDO1,IDO2,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ISG20,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JADE2,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ15,KCNJ2,KCTD14,KIF11,KIF15,KIF18B,KIF23,KIF26A,KITLG,KLF4,KLRK1,KPNA5,KREMEN1,LACTB,LAG3,LAMB3,LAMP3,LAMP5,LAP3,LBH,LCLAT1,LGALS3BP,LGI2,LILRA1,LILRA2,LILRB3,LIMK2,LITAF,LMTK2,LPL,LRATD1,LRP5,LRRC61,LRRK2,LTA,LTC4S,LY75,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MAP1LC3C,MARCKSL1,MARVELD2,MCF2L,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MDGA1,MEFV,MEIKIN,MERTK,MGAM2,MICAL2,MIR503,MKI67,MMD,MMP25,MMP9,MPZL2,MRAS,MSRB1,MT2A,MTHFD2,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYO7B,MYOF,MYOZ2,NAAA,NCAPG,NCAPG2,NCAPH,NCF1,NCF1C,NDC80,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRN1,NRP1,NUB1,NUCB1,NUF2,NUSAP1,NXPH2,NYAP2,OAS2,OAS3,OCA2,OIP5,OLFML2B,OLIG1,ONECUT2,OPTN,OR2I1P,ORC1,OSBPL6,OSM,OTUD1,OVOL1,P2RX4,P2RX7,P2RY14,PADI2,PAQR5,PAQR8,PARP10,PARP12,PARP14,PARP3,PARP9,PCDH12,PCDHGC3,PCLAF,PCYT1A,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKD1L3,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POLB,POLE2,POMP,PPA1,PPM1E,PRC1,PRKX,PROK2,PRRG4,PRRT2,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PSTPIP2,PTGER4,PTPRU,PXN,PYHIN1,PYROXD2,PZP,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGEF1C,RASGRF1,RBP7,RECQL4,REEP1,RELB,REPS2,RGS18,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,RSAD2,RSU1,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCARF1,SCG3,SCIMP,SCIN,SCN4B,SCO2,SDC2,SDC3,SECTM1,SELENOP,SELL,SEMA6B,SEPTIN4,SERINC5,SERPING1,SESN3,SGPL1,SH3PXD2A,SHCBP1,SIDT1,SIDT2,SIGLEC12,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SMCO4,SNX10,SNX20,SOAT1,SOBP,SOCS1,SOX17,SP110,SP140,SPATA9,SPC24,SPC25,SPTBN4,SQOR,SRI,SSBP3,SSPN,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STEAP4,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNC,SYNE1,SYNGR3,SYT1,SYT6,TACC2,TAGAP,TAL1,TANK,TAP1,TAP2,TAPBP,TAPBPL,TBATA,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TICRR,TIFA,TIFAB,TK1,TLR10,TLR5,TLR7,TLR8,TMEM106C,TMEM109,TMEM119,TMEM144,TMEM150A,TMEM176A,TMEM176B,TMEM255A,TMSB10,TMT1B,TMTC1,TNFAIP2,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TPCN1,TRABD2A,TRAFD1,TRDN,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TSPAN32,TTC39B,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,USP53,USP6NL,VAMP5,VCAM1,VCAN,VEGFC,VPS9D1,VRK2,VWCE,WARS1,WDR62,WDR76,WEE1,WWP1,XAF1,XIRP1,XKR6,XRCC2,XRN1,XYLT1,ZBP1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1,ZWINT"} {"GO.ID":"GO:0033043","Term":"regulation of organelle organization","Annotated":1076,"Significant":74,"Expected":64.99,"Rank in p.value_classic":1532,"p.value_elim":0.6304,"p.value_classic":0.12856,"genes":"ATP13A2,AURKB,BCL2L11,BIRC5,BRCA1,BUB1B,CALCOCO2,CCNF,CD28,CDC6,CDH5,CDK1,CDKL1,CELSR1,CENPF,CHMP4C,CYLD,DAZL,EDN1,ERC2,FAM107A,FEN1,FSCN1,GCH1,HGF,HORMAD1,LIMK2,LRP5,LRRK2,MAD2L1,MKI67,MMP9,MTSS1,NCAPG,NCAPG2,NCAPH,NDC80,NOD2,NPM2,NRP1,NUF2,NUSAP1,P2RX7,PARP3,PID1,PKIB,PKMYT1,PLEK,PMAIP1,PML,PPM1E,PRRT2,PTGER4,PXN,RALB,RMI2,S100A10,S1PR1,SCIN,SLAMF1,SPC24,SPC25,SPTBN4,STAT2,STMN1,SYNE1,SYT1,TAL1,TMSB10,TNFSF10,TOP2A,USP6NL,XRN1,ZWINT"} {"GO.ID":"GO:0009566","Term":"fertilization","Annotated":107,"Significant":6,"Expected":6.46,"Rank in p.value_classic":3448,"p.value_elim":0.63055,"p.value_classic":0.63303,"genes":"CDK1,NPM2,PLB1,SPTBN4,SYT6,TDRD9"} {"GO.ID":"GO:0055123","Term":"digestive system development","Annotated":107,"Significant":6,"Expected":6.46,"Rank in p.value_classic":3449,"p.value_elim":0.63055,"p.value_classic":0.63303,"genes":"AGR2,CYP1A1,DNAAF1,EPHB3,SOX17,TYMS"} {"GO.ID":"GO:0043062","Term":"extracellular structure organization","Annotated":264,"Significant":15,"Expected":15.94,"Rank in p.value_classic":3458,"p.value_elim":0.63092,"p.value_classic":0.63484,"genes":"ADAM8,ADAMTS15,AGT,ANTXR1,COL23A1,COL9A2,COLGALT2,COLQ,COMP,CTSS,FSCN1,MMP25,MMP9,OLFML2B,RXFP1"} {"GO.ID":"GO:0045229","Term":"external encapsulating structure organization","Annotated":264,"Significant":15,"Expected":15.94,"Rank in p.value_classic":3459,"p.value_elim":0.63092,"p.value_classic":0.63484,"genes":"ADAM8,ADAMTS15,AGT,ANTXR1,COL23A1,COL9A2,COLGALT2,COLQ,COMP,CTSS,FSCN1,MMP25,MMP9,OLFML2B,RXFP1"} {"GO.ID":"GO:0006693","Term":"prostaglandin metabolic process","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3450,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"CD74,EDN1"} {"GO.ID":"GO:0044331","Term":"cell-cell adhesion mediated by cadherin","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3451,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"CDH5,PTPRU"} {"GO.ID":"GO:2000378","Term":"negative regulation of reactive oxygen species metabolic process","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3452,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"BRCA1,CTNS"} {"GO.ID":"GO:0051438","Term":"regulation of ubiquitin-protein transferase activity","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3453,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"DTX3L,MAD2L1"} {"GO.ID":"GO:0035337","Term":"fatty-acyl-CoA metabolic process","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3454,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"ACSL1,DGAT2"} {"GO.ID":"GO:0022602","Term":"ovulation cycle process","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3455,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"SGPL1,TNFAIP6"} {"GO.ID":"GO:0051693","Term":"actin filament capping","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3456,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"SCIN,SPTBN4"} {"GO.ID":"GO:0120033","Term":"negative regulation of plasma membrane bounded cell projection assembly","Annotated":35,"Significant":2,"Expected":2.11,"Rank in p.value_classic":3457,"p.value_elim":0.63175,"p.value_classic":0.63315,"genes":"LIMK2,STAP1"} {"GO.ID":"GO:0000209","Term":"protein polyubiquitination","Annotated":247,"Significant":14,"Expected":14.92,"Rank in p.value_classic":3461,"p.value_elim":0.63266,"p.value_classic":0.63644,"genes":"BRCA1,DTL,DTX3L,IFI27,NMI,NOD2,PARP10,RIPK2,RNF19B,RNF213,TRIM22,TRIM31,UBE2L6,UBE2T"} {"GO.ID":"GO:0071805","Term":"potassium ion transmembrane transport","Annotated":125,"Significant":7,"Expected":7.55,"Rank in p.value_classic":3460,"p.value_elim":0.63346,"p.value_classic":0.63613,"genes":"ANK2,ATP1B2,KCNE5,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"GO.ID":"GO:0048284","Term":"organelle fusion","Annotated":144,"Significant":12,"Expected":8.7,"Rank in p.value_classic":1679,"p.value_elim":0.63656,"p.value_classic":0.16089,"genes":"ATP13A2,BCL2A1,CDK1,CHMP4C,ERC2,PID1,PRRT2,RAB20,SLAMF1,STX11,STX1A,SYT1"} {"GO.ID":"GO:0006793","Term":"phosphorus metabolic process","Annotated":2179,"Significant":146,"Expected":131.6,"Rank in p.value_classic":1323,"p.value_elim":0.63708,"p.value_classic":0.08675,"genes":"AATK,ACOT4,ACSL1,AGT,AK1,ANKH,ATP13A2,AURKB,BANK1,BIRC5,BUB1B,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CEACAM1,CIITA,CISH,CLEC6A,CLSPN,CMPK2,CSF1,CTNS,CX3CR1,DAB2,DAPP1,DEPTOR,DGAT2,DPYS,DTNBP1,EDN1,ENPP2,EPHB3,FAM20A,FAS,FAXDC2,G6PC1,GIMAP7,GK,GTPBP1,HBEGF,HGF,HLA-DRB1,IDO1,IDO2,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JAK2,JAK3,KARS1,KITLG,LCLAT1,LIMK2,LMTK2,LPL,LRP5,LRRK2,LYN,MCM7,MERTK,MMD,MMP9,MVP,NAAA,NCF1,NLRC5,NLRP12,NOD2,NPR1,NRK,NRP1,OSM,P2RX7,PARP10,PARP14,PARP9,PCYT1A,PDE4B,PDK4,PID1,PIM1,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PNPLA3,PPA1,PPM1E,PRKX,PTPRU,RALB,RAPGEF2,RIPK2,RRM2,SERINC5,SLAMF8,SLC11A1,SLC20A1,SLC2A6,SLC4A7,SOCS1,SPTBN4,STAP1,STAT2,TK1,TLR7,TLR8,TMEM119,TMEM150A,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFSF18,TYMP,TYMS,TYRO3,UNG,VEGFC,VPS9D1,VRK2,WARS1,WEE1,ZC3H12A"} {"GO.ID":"GO:0060419","Term":"heart growth","Annotated":72,"Significant":4,"Expected":4.35,"Rank in p.value_classic":3462,"p.value_elim":0.63759,"p.value_classic":0.6396,"genes":"CDK1,EDN1,PIM1,S1PR1"} {"GO.ID":"GO:0003333","Term":"amino acid transmembrane transport","Annotated":72,"Significant":4,"Expected":4.35,"Rank in p.value_classic":3463,"p.value_elim":0.63759,"p.value_classic":0.6396,"genes":"KCNJ10,SLC11A1,SLC16A10,SLC6A12"} {"GO.ID":"GO:0001708","Term":"cell fate specification","Annotated":72,"Significant":4,"Expected":4.35,"Rank in p.value_classic":3464,"p.value_elim":0.63759,"p.value_classic":0.6396,"genes":"DLL1,NRP1,SOX17,TBX21"} {"GO.ID":"GO:0048864","Term":"stem cell development","Annotated":72,"Significant":4,"Expected":4.35,"Rank in p.value_classic":3465,"p.value_elim":0.63759,"p.value_classic":0.6396,"genes":"EDN1,KITLG,NRP1,SEMA6B"} {"GO.ID":"GO:0043543","Term":"protein acylation","Annotated":90,"Significant":5,"Expected":5.44,"Rank in p.value_classic":3466,"p.value_elim":0.63799,"p.value_classic":0.64024,"genes":"DSCC1,ESCO2,GLUL,PML,ZDHHC19"} {"GO.ID":"GO:0048010","Term":"vascular endothelial growth factor receptor signaling pathway","Annotated":54,"Significant":3,"Expected":3.26,"Rank in p.value_classic":3467,"p.value_elim":0.63956,"p.value_classic":0.64129,"genes":"DLL1,NRP1,VEGFC"} {"GO.ID":"GO:0050709","Term":"negative regulation of protein secretion","Annotated":54,"Significant":3,"Expected":3.26,"Rank in p.value_classic":3468,"p.value_elim":0.63956,"p.value_classic":0.64129,"genes":"GHRL,IL12A,RSAD2"} {"GO.ID":"GO:0043462","Term":"regulation of ATP-dependent activity","Annotated":54,"Significant":3,"Expected":3.26,"Rank in p.value_classic":3469,"p.value_elim":0.63956,"p.value_classic":0.64129,"genes":"ATP1B2,PLSCR1,UHRF1"} {"GO.ID":"GO:0060997","Term":"dendritic spine morphogenesis","Annotated":54,"Significant":3,"Expected":3.26,"Rank in p.value_classic":3470,"p.value_elim":0.63956,"p.value_classic":0.64129,"genes":"DTNBP1,EPHB3,LRRK2"} {"GO.ID":"GO:0007156","Term":"homophilic cell adhesion via plasma membrane adhesion molecules","Annotated":108,"Significant":6,"Expected":6.52,"Rank in p.value_classic":3471,"p.value_elim":0.63957,"p.value_classic":0.64204,"genes":"CDH5,CEACAM1,CELSR1,MPZL2,PCDH12,PCDHGC3"} {"GO.ID":"GO:0019953","Term":"sexual reproduction","Annotated":710,"Significant":50,"Expected":42.88,"Rank in p.value_classic":1618,"p.value_elim":0.63981,"p.value_classic":0.14231,"genes":"ADGB,BCL2L11,BCL6,CCNE2,CDC25A,CDK1,CXADR,DAZL,DMC1,EDN1,EME1,EXO1,HORMAD1,IGF2R,LIMK2,LRRK2,MEIKIN,MERTK,NCAPH,NDC80,NPM2,NUF2,OCA2,OVOL1,PAQR5,PAQR8,PIWIL4,PKMYT1,PLB1,PROK2,RAD54B,RAD54L,SELENOP,SEPTIN4,SGPL1,SOX17,SPATA9,SPTBN4,SSTR2,SYNE1,SYT6,TBATA,TDRD9,TMEM119,TNFAIP6,TOP2A,TYRO3,XRCC2,ZMYND15,ZWINT"} {"GO.ID":"GO:0098655","Term":"monoatomic cation transmembrane transport","Annotated":578,"Significant":42,"Expected":34.91,"Rank in p.value_classic":1509,"p.value_elim":0.64207,"p.value_classic":0.12108,"genes":"ANK2,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,CACNA2D3,CALHM6,CAMK2D,CTNS,CTSS,CXCL10,CXCL11,CXCL9,EDN1,F2RL3,GRIN3A,KCNE5,KCNJ10,KCNJ15,KCNJ2,LYN,MCOLN2,MMP9,P2RX4,P2RX7,PDE4B,PKD1L3,PML,SCN4B,SLC11A1,SLC12A3,SLC18A1,SLC20A1,SLC25A28,SLC31A2,SLC4A7,SLC6A12,SRI,TESC,TMEM109,TPCN1,TRDN"} {"GO.ID":"GO:0120032","Term":"regulation of plasma membrane bounded cell projection assembly","Annotated":179,"Significant":10,"Expected":10.81,"Rank in p.value_classic":3473,"p.value_elim":0.64319,"p.value_classic":0.64636,"genes":"ANLN,ATP8B1,CDKL1,CYLD,FSCN1,ICAM1,LIMK2,NRP1,P2RX7,STAP1"} {"GO.ID":"GO:1901570","Term":"fatty acid derivative biosynthetic process","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3475,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"ACSL1,GGT5"} {"GO.ID":"GO:0006692","Term":"prostanoid metabolic process","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3476,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"CD74,EDN1"} {"GO.ID":"GO:0006636","Term":"unsaturated fatty acid biosynthetic process","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3477,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"CD74,EDN1"} {"GO.ID":"GO:0060119","Term":"inner ear receptor cell development","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3478,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"ATP8B1,SLC4A7"} {"GO.ID":"GO:0060711","Term":"labyrinthine layer development","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3479,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"PCDH12,PLCD3"} {"GO.ID":"GO:0045023","Term":"G0 to G1 transition","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3480,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"HLA-G,MIR503"} {"GO.ID":"GO:0051480","Term":"regulation of cytosolic calcium ion concentration","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3481,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"ERC2,SV2B"} {"GO.ID":"GO:0031279","Term":"regulation of cyclase activity","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3482,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0038179","Term":"neurotrophin signaling pathway","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3483,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"AGT,RAPGEF2"} {"GO.ID":"GO:0048713","Term":"regulation of oligodendrocyte differentiation","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3484,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"SLC45A3,TNFRSF21"} {"GO.ID":"GO:0071539","Term":"protein localization to centrosome","Annotated":36,"Significant":2,"Expected":2.17,"Rank in p.value_classic":3485,"p.value_elim":0.64713,"p.value_classic":0.64853,"genes":"SNX10,TRIM69"} {"GO.ID":"GO:0048167","Term":"regulation of synaptic plasticity","Annotated":162,"Significant":9,"Expected":9.78,"Rank in p.value_classic":3486,"p.value_elim":0.6472,"p.value_classic":0.6502,"genes":"CD38,CX3CR1,EGR2,ERC2,FAM107A,KCNJ10,PRRT2,RAPGEF2,RASGRF1"} {"GO.ID":"GO:0061138","Term":"morphogenesis of a branching epithelium","Annotated":162,"Significant":9,"Expected":9.78,"Rank in p.value_classic":3487,"p.value_elim":0.6472,"p.value_classic":0.6502,"genes":"AGT,CELSR1,CSF1,EDN1,HGF,LRP5,NRP1,PML,TGM2"} {"GO.ID":"GO:0051251","Term":"positive regulation of lymphocyte activation","Annotated":285,"Significant":48,"Expected":17.21,"Rank in p.value_classic":104,"p.value_elim":0.64797,"p.value_classic":7.4e-11,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CD83,CYLD,GPR183,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL15RA,IL4I1,IL7,JAK2,KITLG,KLRK1,LYN,NOD2,PDCD1LG2,RIPK2,SLAMF1,SOCS1,TBX21,TICAM2,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:2000027","Term":"regulation of animal organ morphogenesis","Annotated":73,"Significant":4,"Expected":4.41,"Rank in p.value_classic":3488,"p.value_elim":0.64841,"p.value_classic":0.65041,"genes":"AGT,CSF1,EDN1,HGF"} {"GO.ID":"GO:0001952","Term":"regulation of cell-matrix adhesion","Annotated":109,"Significant":6,"Expected":6.58,"Rank in p.value_classic":3489,"p.value_elim":0.64846,"p.value_classic":0.65091,"genes":"BCL6,CSF1,FAM107A,NRP1,ONECUT2,S100A10"} {"GO.ID":"GO:0071902","Term":"positive regulation of protein serine/threonine kinase activity","Annotated":109,"Significant":6,"Expected":6.58,"Rank in p.value_classic":3490,"p.value_elim":0.64846,"p.value_classic":0.65091,"genes":"CD40,EDN1,LRRK2,RALB,RAPGEF2,TNFRSF11A"} {"GO.ID":"GO:0034502","Term":"protein localization to chromosome","Annotated":109,"Significant":6,"Expected":6.58,"Rank in p.value_classic":3491,"p.value_elim":0.64846,"p.value_classic":0.65091,"genes":"AURKB,BUB1B,CDK1,ESCO2,PARP3,TONSL"} {"GO.ID":"GO:0045598","Term":"regulation of fat cell differentiation","Annotated":109,"Significant":6,"Expected":6.58,"Rank in p.value_classic":3492,"p.value_elim":0.64846,"p.value_classic":0.65091,"genes":"CDS1,E2F1,LPL,LRP5,PIM1,ZC3H12A"} {"GO.ID":"GO:0043524","Term":"negative regulation of neuron apoptotic process","Annotated":127,"Significant":7,"Expected":7.67,"Rank in p.value_classic":3493,"p.value_elim":0.65003,"p.value_classic":0.65267,"genes":"ADAM8,CX3CR1,JAK2,NRP1,PCDHGC3,TYRO3,XRCC2"} {"GO.ID":"GO:0048813","Term":"dendrite morphogenesis","Annotated":127,"Significant":7,"Expected":7.67,"Rank in p.value_classic":3494,"p.value_elim":0.65003,"p.value_classic":0.65267,"genes":"DTNBP1,EPHB3,LRRK2,NRP1,RAPGEF2,SDC2,SYNE1"} {"GO.ID":"GO:0070542","Term":"response to fatty acid","Annotated":43,"Significant":7,"Expected":2.6,"Rank in p.value_classic":808,"p.value_elim":0.65034,"p.value_classic":0.0137,"genes":"ACSL1,DGAT2,EDN1,LPL,PDK4,PID1,ZC3H12A"} {"GO.ID":"GO:0009262","Term":"deoxyribonucleotide metabolic process","Annotated":39,"Significant":6,"Expected":2.36,"Rank in p.value_classic":962,"p.value_elim":0.65071,"p.value_classic":0.02821,"genes":"CMPK2,DPYS,RRM2,TYMP,TYMS,UNG"} {"GO.ID":"GO:0019692","Term":"deoxyribose phosphate metabolic process","Annotated":39,"Significant":6,"Expected":2.36,"Rank in p.value_classic":963,"p.value_elim":0.65071,"p.value_classic":0.02821,"genes":"CMPK2,DPYS,RRM2,TYMP,TYMS,UNG"} {"GO.ID":"GO:0045005","Term":"DNA-templated DNA replication maintenance of fidelity","Annotated":55,"Significant":3,"Expected":3.32,"Rank in p.value_classic":3535,"p.value_elim":0.65195,"p.value_classic":0.65367,"genes":"BRCA1,EME1,TONSL"} {"GO.ID":"GO:0048255","Term":"mRNA stabilization","Annotated":55,"Significant":3,"Expected":3.32,"Rank in p.value_classic":3536,"p.value_elim":0.65195,"p.value_classic":0.65367,"genes":"DAZL,E2F1,SLC11A1"} {"GO.ID":"GO:0008652","Term":"amino acid biosynthetic process","Annotated":55,"Significant":3,"Expected":3.32,"Rank in p.value_classic":3537,"p.value_elim":0.65195,"p.value_classic":0.65367,"genes":"DHFR,GLUL,SERINC5"} {"GO.ID":"GO:1901568","Term":"fatty acid derivative metabolic process","Annotated":55,"Significant":3,"Expected":3.32,"Rank in p.value_classic":3538,"p.value_elim":0.65195,"p.value_classic":0.65367,"genes":"ACSL1,DGAT2,GGT5"} {"GO.ID":"GO:0046626","Term":"regulation of insulin receptor signaling pathway","Annotated":55,"Significant":3,"Expected":3.32,"Rank in p.value_classic":3539,"p.value_elim":0.65195,"p.value_classic":0.65367,"genes":"PID1,SESN3,SOCS1"} {"GO.ID":"GO:0001963","Term":"synaptic transmission, dopaminergic","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3495,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CRHBP"} {"GO.ID":"GO:0001964","Term":"startle response","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3496,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"GRIN3A"} {"GO.ID":"GO:0061952","Term":"midbody abscission","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3497,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CHMP4C"} {"GO.ID":"GO:0090189","Term":"regulation of branching involved in ureteric bud morphogenesis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3498,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"AGT"} {"GO.ID":"GO:0000212","Term":"meiotic spindle organization","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3499,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"NDC80"} {"GO.ID":"GO:0002026","Term":"regulation of the force of heart contraction","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3500,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CAMK2D"} {"GO.ID":"GO:0035970","Term":"peptidyl-threonine dephosphorylation","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3501,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"PPM1E"} {"GO.ID":"GO:0070102","Term":"interleukin-6-mediated signaling pathway","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3502,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"JAK2"} {"GO.ID":"GO:2000047","Term":"regulation of cell-cell adhesion mediated by cadherin","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3503,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"PTPRU"} {"GO.ID":"GO:0010566","Term":"regulation of ketone biosynthetic process","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3504,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"DAB2"} {"GO.ID":"GO:0120255","Term":"olefinic compound biosynthetic process","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3505,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"DAB2"} {"GO.ID":"GO:0010587","Term":"miRNA catabolic process","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3506,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"ZC3H12A"} {"GO.ID":"GO:0060716","Term":"labyrinthine layer blood vessel development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3507,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"PLCD3"} {"GO.ID":"GO:0060749","Term":"mammary gland alveolus development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3508,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"TNFRSF11A"} {"GO.ID":"GO:0071025","Term":"RNA surveillance","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3509,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"XRN1"} {"GO.ID":"GO:1900117","Term":"regulation of execution phase of apoptosis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3510,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"ZC3H12A"} {"GO.ID":"GO:0007063","Term":"regulation of sister chromatid cohesion","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3511,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"FEN1"} {"GO.ID":"GO:0042474","Term":"middle ear morphogenesis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3512,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"EDN1"} {"GO.ID":"GO:1900242","Term":"regulation of synaptic vesicle endocytosis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3513,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"LRRK2"} {"GO.ID":"GO:1902004","Term":"positive regulation of amyloid-beta formation","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3514,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"GSAP"} {"GO.ID":"GO:0006085","Term":"acetyl-CoA biosynthetic process","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3515,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"PDK4"} {"GO.ID":"GO:0003283","Term":"atrial septum development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3516,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"ANK2"} {"GO.ID":"GO:0071391","Term":"cellular response to estrogen stimulus","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3517,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CRHBP"} {"GO.ID":"GO:0071397","Term":"cellular response to cholesterol","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3518,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"GRAMD1B"} {"GO.ID":"GO:0061377","Term":"mammary gland lobule development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3519,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"TNFRSF11A"} {"GO.ID":"GO:0072170","Term":"metanephric tubule development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3520,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"STAT1"} {"GO.ID":"GO:0021895","Term":"cerebral cortex neuron differentiation","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3521,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"C21orf91"} {"GO.ID":"GO:1901380","Term":"negative regulation of potassium ion transmembrane transport","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3522,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"KCNE5"} {"GO.ID":"GO:0072202","Term":"cell differentiation involved in metanephros development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3523,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"STAT1"} {"GO.ID":"GO:0060973","Term":"cell migration involved in heart development","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3524,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"EDN1"} {"GO.ID":"GO:2001026","Term":"regulation of endothelial cell chemotaxis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3525,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"P2RX4"} {"GO.ID":"GO:0032510","Term":"endosome to lysosome transport via multivesicular body sorting pathway","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3526,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CHMP4C"} {"GO.ID":"GO:0071731","Term":"response to nitric oxide","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3527,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"CCNA2"} {"GO.ID":"GO:0040037","Term":"negative regulation of fibroblast growth factor receptor signaling pathway","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3528,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"MIR503"} {"GO.ID":"GO:0072673","Term":"lamellipodium morphogenesis","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3529,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"ENPP2"} {"GO.ID":"GO:1904666","Term":"regulation of ubiquitin protein ligase activity","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3530,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"MAD2L1"} {"GO.ID":"GO:0006895","Term":"Golgi to endosome transport","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3531,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"DOP1A"} {"GO.ID":"GO:0007549","Term":"sex-chromosome dosage compensation","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3532,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"BRCA1"} {"GO.ID":"GO:1901881","Term":"positive regulation of protein depolymerization","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3533,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"PLEK"} {"GO.ID":"GO:1902570","Term":"protein localization to nucleolus","Annotated":17,"Significant":1,"Expected":1.03,"Rank in p.value_classic":3534,"p.value_elim":0.65248,"p.value_classic":0.65344,"genes":"GLUL"} {"GO.ID":"GO:0045893","Term":"positive regulation of DNA-templated transcription","Annotated":1410,"Significant":82,"Expected":85.16,"Rank in p.value_classic":3548,"p.value_elim":0.65409,"p.value_classic":0.66338,"genes":"ABLIM3,AGT,ASCL2,ATF3,ATF5,BACH1,BMAL2,BRCA1,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CIITA,CXCL10,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,HGF,HLA-DRB1,IL31RA,IL4I1,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,PARP9,PID1,PIM1,PLSCR1,PYHIN1,RELB,RIPK2,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TLR7,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0062012","Term":"regulation of small molecule metabolic process","Annotated":251,"Significant":14,"Expected":15.16,"Rank in p.value_classic":3542,"p.value_elim":0.65641,"p.value_classic":0.66013,"genes":"APPL2,BRCA1,CD74,CEACAM1,DAB2,NR4A3,P2RX7,PDK4,PID1,PLEK,PMAIP1,SLC2A6,SLC45A3,TTC39B"} {"GO.ID":"GO:0060491","Term":"regulation of cell projection assembly","Annotated":181,"Significant":10,"Expected":10.93,"Rank in p.value_classic":3543,"p.value_elim":0.65699,"p.value_classic":0.66013,"genes":"ANLN,ATP8B1,CDKL1,CYLD,FSCN1,ICAM1,LIMK2,NRP1,P2RX7,STAP1"} {"GO.ID":"GO:1902652","Term":"secondary alcohol metabolic process","Annotated":110,"Significant":6,"Expected":6.64,"Rank in p.value_classic":3541,"p.value_elim":0.65721,"p.value_classic":0.65965,"genes":"APOL1,APOL2,LRP5,SCARF1,SOAT1,TTC39B"} {"GO.ID":"GO:1900542","Term":"regulation of purine nucleotide metabolic process","Annotated":74,"Significant":4,"Expected":4.47,"Rank in p.value_classic":3544,"p.value_elim":0.65902,"p.value_classic":0.661,"genes":"P2RX7,PDK4,PID1,SLC2A6"} {"GO.ID":"GO:0043648","Term":"dicarboxylic acid metabolic process","Annotated":74,"Significant":4,"Expected":4.47,"Rank in p.value_classic":3545,"p.value_elim":0.65902,"p.value_classic":0.661,"genes":"ACOT4,DHFR,GLUL,MTHFD2"} {"GO.ID":"GO:0006140","Term":"regulation of nucleotide metabolic process","Annotated":74,"Significant":4,"Expected":4.47,"Rank in p.value_classic":3546,"p.value_elim":0.65902,"p.value_classic":0.661,"genes":"P2RX7,PDK4,PID1,SLC2A6"} {"GO.ID":"GO:1901873","Term":"regulation of post-translational protein modification","Annotated":234,"Significant":13,"Expected":14.13,"Rank in p.value_classic":3547,"p.value_elim":0.65919,"p.value_classic":0.66276,"genes":"AMER1,DTX3L,EPAS1,FAM107A,LRRK2,MAD2L1,NMI,NOD2,PARP10,RIPK2,SEPTIN4,TANK,ZC3H12A"} {"GO.ID":"GO:0051656","Term":"establishment of organelle localization","Annotated":425,"Significant":24,"Expected":25.67,"Rank in p.value_classic":3564,"p.value_elim":0.65999,"p.value_classic":0.66485,"genes":"ATP13A2,AURKB,BIRC5,CADPS2,CDCA5,CDT1,CENPF,CHMP4C,DNM1,DTNBP1,DYNLT1,EML4,LIMK2,LRRK2,LYN,MAD2L1,NDC80,NR4A3,NUF2,NUSAP1,S100A13,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0051223","Term":"regulation of protein transport","Annotated":356,"Significant":20,"Expected":21.5,"Rank in p.value_classic":3565,"p.value_elim":0.66048,"p.value_classic":0.66491,"genes":"ADAM8,ATP13A2,CCL5,CD38,CDK1,DERL3,GHRL,HCAR2,HLA-DRB1,IFI27,IL12A,JAK2,LRP5,P2RX7,RSAD2,SIDT2,SRI,STX1A,VEGFC,ZC3H12A"} {"GO.ID":"GO:0003002","Term":"regionalization","Annotated":304,"Significant":17,"Expected":18.36,"Rank in p.value_classic":3563,"p.value_elim":0.66067,"p.value_classic":0.66475,"genes":"ASB2,BHLHE41,C3,CHRD,DLL1,DNAAF1,EDN1,EGR2,IFT122,LRP5,MICAL2,NRP1,PLXNA2,SOX17,SSBP3,TIFAB,XRCC2"} {"GO.ID":"GO:1902680","Term":"positive regulation of RNA biosynthetic process","Annotated":1413,"Significant":82,"Expected":85.34,"Rank in p.value_classic":3574,"p.value_elim":0.6619,"p.value_classic":0.67111,"genes":"ABLIM3,AGT,ASCL2,ATF3,ATF5,BACH1,BMAL2,BRCA1,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CIITA,CXCL10,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,HGF,HLA-DRB1,IL31RA,IL4I1,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,PARP9,PID1,PIM1,PLSCR1,PYHIN1,RELB,RIPK2,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TLR7,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,ZC3H12A,ZNF395"} {"GO.ID":"GO:1901532","Term":"regulation of hematopoietic progenitor cell differentiation","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3549,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"KITLG,OSM"} {"GO.ID":"GO:0009124","Term":"nucleoside monophosphate biosynthetic process","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3550,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"TK1,TYMS"} {"GO.ID":"GO:0043001","Term":"Golgi to plasma membrane protein transport","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3551,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"OPTN,VAMP5"} {"GO.ID":"GO:1902930","Term":"regulation of alcohol biosynthetic process","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3552,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"DAB2,PLEK"} {"GO.ID":"GO:1905508","Term":"protein localization to microtubule organizing center","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3553,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"SNX10,TRIM69"} {"GO.ID":"GO:0044273","Term":"sulfur compound catabolic process","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3554,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"CHAC1,GGT5"} {"GO.ID":"GO:0061383","Term":"trabecula morphogenesis","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3555,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"S1PR1,SBNO2"} {"GO.ID":"GO:0031111","Term":"negative regulation of microtubule polymerization or depolymerization","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3556,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"CDH5,STMN1"} {"GO.ID":"GO:0035315","Term":"hair cell differentiation","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3557,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"DLL1,SLC4A7"} {"GO.ID":"GO:0043506","Term":"regulation of JUN kinase activity","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3558,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"EDN1,TNFRSF11A"} {"GO.ID":"GO:0016233","Term":"telomere capping","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3559,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"AURKB,PKIB"} {"GO.ID":"GO:2000648","Term":"positive regulation of stem cell proliferation","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3560,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"KITLG,VEGFC"} {"GO.ID":"GO:0071548","Term":"response to dexamethasone","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3561,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"EDN1,JAK2"} {"GO.ID":"GO:0071634","Term":"regulation of transforming growth factor beta production","Annotated":37,"Significant":2,"Expected":2.23,"Rank in p.value_classic":3562,"p.value_elim":0.66199,"p.value_classic":0.66338,"genes":"ADAM8,AGT"} {"GO.ID":"GO:2001244","Term":"positive regulation of intrinsic apoptotic signaling pathway","Annotated":56,"Significant":3,"Expected":3.38,"Rank in p.value_classic":3566,"p.value_elim":0.66403,"p.value_classic":0.66574,"genes":"BCL2L11,PMAIP1,SEPTIN4"} {"GO.ID":"GO:0030166","Term":"proteoglycan biosynthetic process","Annotated":56,"Significant":3,"Expected":3.38,"Rank in p.value_classic":3567,"p.value_elim":0.66403,"p.value_classic":0.66574,"genes":"DSE,GAL3ST4,XYLT1"} {"GO.ID":"GO:0030837","Term":"negative regulation of actin filament polymerization","Annotated":56,"Significant":3,"Expected":3.38,"Rank in p.value_classic":3568,"p.value_elim":0.66403,"p.value_classic":0.66574,"genes":"SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0048814","Term":"regulation of dendrite morphogenesis","Annotated":56,"Significant":3,"Expected":3.38,"Rank in p.value_classic":3569,"p.value_elim":0.66403,"p.value_classic":0.66574,"genes":"RAPGEF2,SDC2,SYNE1"} {"GO.ID":"GO:1905330","Term":"regulation of morphogenesis of an epithelium","Annotated":56,"Significant":3,"Expected":3.38,"Rank in p.value_classic":3570,"p.value_elim":0.66403,"p.value_classic":0.66574,"genes":"AGT,CXCL10,HGF"} {"GO.ID":"GO:0000226","Term":"microtubule cytoskeleton organization","Annotated":559,"Significant":35,"Expected":33.76,"Rank in p.value_classic":2591,"p.value_elim":0.66504,"p.value_classic":0.43725,"genes":"ATF5,AURKB,BIRC5,BRCA1,CCDC170,CCNF,CDH5,CDK1,CHMP4C,CYLD,DNAAF1,DYNLT1,EML4,FAM107A,KIF11,KIF18B,KIF23,LIMK2,LRRC61,MAD2L1,MYBL2,NDC80,NUF2,NUSAP1,PARP3,PCLAF,PRC1,SPC25,STMN1,TACC2,TRDN,UHRF1,WDR62,WEE1,XRCC2"} {"GO.ID":"GO:0042752","Term":"regulation of circadian rhythm","Annotated":93,"Significant":5,"Expected":5.62,"Rank in p.value_classic":3572,"p.value_elim":0.66665,"p.value_classic":0.66886,"genes":"BMAL2,CDK1,GHRL,PML,TOP2A"} {"GO.ID":"GO:0006720","Term":"isoprenoid metabolic process","Annotated":93,"Significant":5,"Expected":5.62,"Rank in p.value_classic":3573,"p.value_elim":0.66665,"p.value_classic":0.66886,"genes":"CYP1A1,DGAT2,DHRS3,DHRS9,PLB1"} {"GO.ID":"GO:0051495","Term":"positive regulation of cytoskeleton organization","Annotated":165,"Significant":9,"Expected":9.97,"Rank in p.value_classic":3577,"p.value_elim":0.66868,"p.value_classic":0.67163,"genes":"EDN1,MTSS1,NRP1,P2RX7,PLEK,PPM1E,PXN,S100A10,SCIN"} {"GO.ID":"GO:0060021","Term":"roof of mouth development","Annotated":75,"Significant":4,"Expected":4.53,"Rank in p.value_classic":3576,"p.value_elim":0.66941,"p.value_classic":0.67138,"genes":"DHRS3,EPHB3,MMP25,SGPL1"} {"GO.ID":"GO:1901617","Term":"organic hydroxy compound biosynthetic process","Annotated":183,"Significant":10,"Expected":11.05,"Rank in p.value_classic":3578,"p.value_elim":0.67049,"p.value_classic":0.6736,"genes":"CTNS,DAB2,DHFR,FAXDC2,GCH1,HSD3B7,OCA2,OSBPL6,PLEK,RAPGEF2"} {"GO.ID":"GO:0061448","Term":"connective tissue development","Annotated":236,"Significant":13,"Expected":14.25,"Rank in p.value_classic":3619,"p.value_elim":0.67111,"p.value_classic":0.67464,"genes":"AMER1,COMP,CSF1,DGAT2,EDN1,GHRL,LPL,LRP5,MAF,PLAAT3,RXFP1,SCIN,TYMS"} {"GO.ID":"GO:0045926","Term":"negative regulation of growth","Annotated":201,"Significant":11,"Expected":12.14,"Rank in p.value_classic":3620,"p.value_elim":0.67252,"p.value_classic":0.67577,"genes":"BCL6,BRCA1,CDKN2C,DAB2,FSTL4,MT2A,NPR1,NRP1,PML,SEMA6B,SOX17"} {"GO.ID":"GO:0090335","Term":"regulation of brown fat cell differentiation","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3579,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"PIM1"} {"GO.ID":"GO:0006670","Term":"sphingosine metabolic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3580,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"NAAA"} {"GO.ID":"GO:0006607","Term":"NLS-bearing protein import into nucleus","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3581,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"KPNA5"} {"GO.ID":"GO:0010288","Term":"response to lead ion","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3582,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"PLSCR1"} {"GO.ID":"GO:0010224","Term":"response to UV-B","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3583,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"IL12A"} {"GO.ID":"GO:0030220","Term":"platelet formation","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3584,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"TAL1"} {"GO.ID":"GO:0022010","Term":"central nervous system myelination","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3585,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"KCNJ10"} {"GO.ID":"GO:0090103","Term":"cochlea morphogenesis","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3586,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"TIFAB"} {"GO.ID":"GO:1902932","Term":"positive regulation of alcohol biosynthetic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3587,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DAB2"} {"GO.ID":"GO:0010866","Term":"regulation of triglyceride biosynthetic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3588,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"C3"} {"GO.ID":"GO:0039535","Term":"regulation of RIG-I signaling pathway","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3589,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DDX60"} {"GO.ID":"GO:0099514","Term":"synaptic vesicle cytoskeletal transport","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3590,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DTNBP1"} {"GO.ID":"GO:0099517","Term":"synaptic vesicle transport along microtubule","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3591,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DTNBP1"} {"GO.ID":"GO:0050891","Term":"multicellular organismal-level water homeostasis","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3592,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"CTNS"} {"GO.ID":"GO:0060706","Term":"cell differentiation involved in embryonic placenta development","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3593,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"E2F8"} {"GO.ID":"GO:0046058","Term":"cAMP metabolic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3594,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"PDE4B"} {"GO.ID":"GO:0043249","Term":"erythrocyte maturation","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3595,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"TAL1"} {"GO.ID":"GO:0014850","Term":"response to muscle activity","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3596,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"AGT"} {"GO.ID":"GO:0048311","Term":"mitochondrion distribution","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3597,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"LRRK2"} {"GO.ID":"GO:0032291","Term":"axon ensheathment in central nervous system","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3598,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"KCNJ10"} {"GO.ID":"GO:0032253","Term":"dense core granule localization","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3599,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"CADPS2"} {"GO.ID":"GO:0048490","Term":"anterograde synaptic vesicle transport","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3600,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DTNBP1"} {"GO.ID":"GO:1990806","Term":"ligand-gated ion channel signaling pathway","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3601,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"GRIN3A"} {"GO.ID":"GO:0033630","Term":"positive regulation of cell adhesion mediated by integrin","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3602,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"CCL5"} {"GO.ID":"GO:0071243","Term":"cellular response to arsenic-containing substance","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3603,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"ZC3H12A"} {"GO.ID":"GO:0007271","Term":"synaptic transmission, cholinergic","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3604,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"COLQ"} {"GO.ID":"GO:0007274","Term":"neuromuscular synaptic transmission","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3605,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"ERC2"} {"GO.ID":"GO:0007214","Term":"gamma-aminobutyric acid signaling pathway","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3606,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"GABRA3"} {"GO.ID":"GO:0009065","Term":"glutamine family amino acid catabolic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3607,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"GLUL"} {"GO.ID":"GO:1902236","Term":"negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3608,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"LRRK2"} {"GO.ID":"GO:0040019","Term":"positive regulation of embryonic development","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3609,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"AMOT"} {"GO.ID":"GO:0035269","Term":"protein O-linked mannosylation","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3610,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"TMTC1"} {"GO.ID":"GO:1903861","Term":"positive regulation of dendrite extension","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3611,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"SYT1"} {"GO.ID":"GO:0031639","Term":"plasminogen activation","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3612,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"S100A10"} {"GO.ID":"GO:0035720","Term":"intraciliary anterograde transport","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3613,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"IFT122"} {"GO.ID":"GO:0048641","Term":"regulation of skeletal muscle tissue development","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3614,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"DLL1"} {"GO.ID":"GO:0035855","Term":"megakaryocyte development","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3615,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"TAL1"} {"GO.ID":"GO:0006595","Term":"polyamine metabolic process","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3616,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"SAT1"} {"GO.ID":"GO:0035584","Term":"calcium-mediated signaling using intracellular calcium source","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3617,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"VCAM1"} {"GO.ID":"GO:0015693","Term":"magnesium ion transport","Annotated":18,"Significant":1,"Expected":1.09,"Rank in p.value_classic":3618,"p.value_elim":0.67344,"p.value_classic":0.6744,"genes":"KCNJ2"} {"GO.ID":"GO:0009887","Term":"animal organ morphogenesis","Annotated":772,"Significant":44,"Expected":46.63,"Rank in p.value_classic":3633,"p.value_elim":0.67472,"p.value_classic":0.68124,"genes":"AGT,ANKH,ASB2,BCL2L11,CEACAM1,CELSR1,COMP,CSF1,CTNS,DHRS3,DLL1,DNAAF1,EDA,EDN1,ETV7,FAM20A,FGL1,GCNT3,HESX1,HGF,IFT122,IL7,LRP5,LRRK2,MICAL2,NRP1,ONECUT2,P2RX7,PIM1,PML,POLB,PRKX,RXFP1,S1PR1,SGPL1,SNX10,SOBP,SOX17,STAT1,TGM2,TIFAB,TMEM119,TMEM176B,VEGFC"} {"GO.ID":"GO:0046903","Term":"secretion","Annotated":726,"Significant":69,"Expected":43.85,"Rank in p.value_classic":364,"p.value_elim":0.67515,"p.value_classic":0.00011,"genes":"ADAM8,ADORA3,AGR2,AGT,ASIC1,ATP13A2,C1QTNF5,CADPS2,CCL5,CCL8,CD38,CD74,CEACAM1,COMP,CRHBP,DAB2,DTNBP1,DYSF,EDN1,ERC2,EXOC3L1,EXOC3L4,GHRL,GSDMD,HCAR2,HLA-DRB1,HLA-F,HRH2,IL12A,IL1RN,ITSN1,JAK2,LRP5,LRRK2,LYN,MCTP2,MERTK,MYOF,NPR1,NR4A3,OAS2,OSM,P2RX4,P2RX7,PLEK,PRRT2,RALB,RSAD2,S100A10,S100A13,SCIN,SEPTIN4,SIDT2,SLC16A10,SNX10,SRI,STX11,STX1A,SUCNR1,SV2B,SYNGR3,SYT1,SYT6,TGM2,TIFAB,TNFAIP2,TNFRSF11A,TYRO3,VEGFC"} {"GO.ID":"GO:0045913","Term":"positive regulation of carbohydrate metabolic process","Annotated":57,"Significant":3,"Expected":3.44,"Rank in p.value_classic":3621,"p.value_elim":0.6758,"p.value_classic":0.67749,"genes":"P2RX7,PMAIP1,SLC45A3"} {"GO.ID":"GO:0033619","Term":"membrane protein proteolysis","Annotated":57,"Significant":3,"Expected":3.44,"Rank in p.value_classic":3622,"p.value_elim":0.6758,"p.value_classic":0.67749,"genes":"ADAM8,P2RX7,TSPAN15"} {"GO.ID":"GO:0043473","Term":"pigmentation","Annotated":94,"Significant":5,"Expected":5.68,"Rank in p.value_classic":3629,"p.value_elim":0.67587,"p.value_classic":0.67805,"genes":"BCL2L11,DTNBP1,EDA,KITLG,OCA2"} {"GO.ID":"GO:0018210","Term":"peptidyl-threonine modification","Annotated":94,"Significant":5,"Expected":5.68,"Rank in p.value_classic":3630,"p.value_elim":0.67587,"p.value_classic":0.67805,"genes":"CAMK2D,CDK1,LMTK2,LRRK2,RIPK2"} {"GO.ID":"GO:0060193","Term":"positive regulation of lipase activity","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3623,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"CCL5,ITK"} {"GO.ID":"GO:0050850","Term":"positive regulation of calcium-mediated signaling","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3624,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"EDN1,P2RX4"} {"GO.ID":"GO:1990776","Term":"response to angiotensin","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3625,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"AGT,CDC6"} {"GO.ID":"GO:0051339","Term":"regulation of lyase activity","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3626,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"ADORA3,RXFP1"} {"GO.ID":"GO:0021587","Term":"cerebellum morphogenesis","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3627,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"DAB1,DLL1"} {"GO.ID":"GO:1902229","Term":"regulation of intrinsic apoptotic signaling pathway in response to DNA damage","Annotated":38,"Significant":2,"Expected":2.3,"Rank in p.value_classic":3628,"p.value_elim":0.67635,"p.value_classic":0.67773,"genes":"CD74,MUC1"} {"GO.ID":"GO:0031344","Term":"regulation of cell projection organization","Annotated":584,"Significant":33,"Expected":35.27,"Rank in p.value_classic":3635,"p.value_elim":0.67671,"p.value_classic":0.68232,"genes":"ANLN,ATP1B2,ATP8B1,B2M,CD38,CDKL1,CYLD,DAB1,DAB2,DTNBP1,ENPP2,EPHB3,FSCN1,FSTL4,ICAM1,IL15RA,KIF26A,KLF4,KREMEN1,LIMK2,LRRK2,LYN,NRCAM,NRP1,P2RX7,PLXNA2,RAPGEF2,RTN4RL1,SCARF1,SDC2,SEMA6B,STAP1,SYNE1"} {"GO.ID":"GO:1903039","Term":"positive regulation of leukocyte cell-cell adhesion","Annotated":237,"Significant":44,"Expected":14.31,"Rank in p.value_classic":91,"p.value_elim":0.67843,"p.value_classic":1.7e-11,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CYLD,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL4I1,IL7,JAK2,KITLG,KLRK1,LYN,NOD2,NR4A3,PDCD1LG2,RIPK2,SLAMF1,SOCS1,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:0050678","Term":"regulation of epithelial cell proliferation","Annotated":290,"Significant":16,"Expected":17.51,"Rank in p.value_classic":3636,"p.value_elim":0.67888,"p.value_classic":0.68277,"genes":"B2M,CCL5,CEACAM1,DAB2,GHRL,IL12A,IQGAP3,MIR503,MTSS1,NOD2,NR4A3,NRP1,OVOL1,STAT1,UHRF1,VEGFC"} {"GO.ID":"GO:0034504","Term":"protein localization to nucleus","Annotated":290,"Significant":16,"Expected":17.51,"Rank in p.value_classic":3637,"p.value_elim":0.67888,"p.value_classic":0.68277,"genes":"APPL2,ATP13A2,CDK1,DTX3L,EDN1,GBP2,GLUL,JAK2,KPNA5,LIMK2,LRRK2,PARP9,PML,PYHIN1,SYNE1,ZC3H12A"} {"GO.ID":"GO:0045185","Term":"maintenance of protein location","Annotated":76,"Significant":4,"Expected":4.59,"Rank in p.value_classic":3634,"p.value_elim":0.67957,"p.value_classic":0.68153,"genes":"PML,SCIN,SYNE1,TMSB10"} {"GO.ID":"GO:0046890","Term":"regulation of lipid biosynthetic process","Annotated":131,"Significant":7,"Expected":7.91,"Rank in p.value_classic":3638,"p.value_elim":0.68181,"p.value_classic":0.68438,"genes":"BRCA1,C3,CD74,CEACAM1,DAB2,PDK4,SLC45A3"} {"GO.ID":"GO:0007519","Term":"skeletal muscle tissue development","Annotated":131,"Significant":7,"Expected":7.91,"Rank in p.value_classic":3639,"p.value_elim":0.68181,"p.value_classic":0.68438,"genes":"ASB2,ATF3,DLL1,EGR2,MAFF,MYOZ2,VAMP5"} {"GO.ID":"GO:0050890","Term":"cognition","Annotated":238,"Significant":13,"Expected":14.37,"Rank in p.value_classic":3640,"p.value_elim":0.68278,"p.value_classic":0.68627,"genes":"ASIC1,B2M,CBR3,CRHBP,CTNS,CX3CR1,EGR2,FAM107A,FEN1,HLA-DRA,RASGRF1,SOBP,TIFAB"} {"GO.ID":"GO:0016049","Term":"cell growth","Annotated":413,"Significant":23,"Expected":24.94,"Rank in p.value_classic":3643,"p.value_elim":0.68372,"p.value_classic":0.68835,"genes":"AGT,BCL6,BRCA1,CAMK2D,CD38,CDKN2C,CEACAM1,CISH,DAB2,EDN1,FAM107A,FSTL4,HBEGF,JADE2,KIF26A,NPR1,NRCAM,NRN1,NRP1,PML,SEMA6B,SOX17,SYT1"} {"GO.ID":"GO:0035967","Term":"cellular response to topologically incorrect protein","Annotated":95,"Significant":5,"Expected":5.74,"Rank in p.value_classic":3641,"p.value_elim":0.68491,"p.value_classic":0.68708,"genes":"AGR2,ATF3,BCL2L11,DERL3,OPTN"} {"GO.ID":"GO:0007613","Term":"memory","Annotated":95,"Significant":5,"Expected":5.74,"Rank in p.value_classic":3642,"p.value_elim":0.68491,"p.value_classic":0.68708,"genes":"ASIC1,CTNS,CX3CR1,FEN1,RASGRF1"} {"GO.ID":"GO:0002700","Term":"regulation of production of molecular mediator of immune response","Annotated":155,"Significant":22,"Expected":9.36,"Rank in p.value_classic":380,"p.value_elim":0.68718,"p.value_classic":0.00016,"genes":"B2M,BCL6,CD28,CD74,HLA-A,HLA-E,HLA-F,HLA-G,JAK3,LITAF,NOD2,NR4A3,P2RX7,PARP3,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:1900076","Term":"regulation of cellular response to insulin stimulus","Annotated":58,"Significant":3,"Expected":3.5,"Rank in p.value_classic":3644,"p.value_elim":0.68726,"p.value_classic":0.68894,"genes":"APPL2,PID1,SOCS1"} {"GO.ID":"GO:1901607","Term":"alpha-amino acid biosynthetic process","Annotated":58,"Significant":3,"Expected":3.5,"Rank in p.value_classic":3645,"p.value_elim":0.68726,"p.value_classic":0.68894,"genes":"DHFR,GLUL,SERINC5"} {"GO.ID":"GO:1903053","Term":"regulation of extracellular matrix organization","Annotated":58,"Significant":3,"Expected":3.5,"Rank in p.value_classic":3646,"p.value_elim":0.68726,"p.value_classic":0.68894,"genes":"AGT,ANTXR1,FSCN1"} {"GO.ID":"GO:0046824","Term":"positive regulation of nucleocytoplasmic transport","Annotated":58,"Significant":3,"Expected":3.5,"Rank in p.value_classic":3647,"p.value_elim":0.68726,"p.value_classic":0.68894,"genes":"CDK1,JAK2,ZC3H12A"} {"GO.ID":"GO:0044283","Term":"small molecule biosynthetic process","Annotated":466,"Significant":26,"Expected":28.14,"Rank in p.value_classic":3664,"p.value_elim":0.68786,"p.value_classic":0.69276,"genes":"ACOT4,ATF3,BRCA1,CD74,CEACAM1,CYP1A1,DAB2,DHFR,DHRS9,DSE,EDN1,G6PC1,GCH1,GGT5,GLUL,HSD3B7,IDO1,LPL,LTC4S,OSBPL6,PDK4,PLEK,PRTFDC1,SERINC5,SLC45A3,TK1"} {"GO.ID":"GO:0001501","Term":"skeletal system development","Annotated":414,"Significant":23,"Expected":25,"Rank in p.value_classic":3663,"p.value_elim":0.68814,"p.value_classic":0.69275,"genes":"AMER1,ANKH,CHRD,COL9A2,COMP,DHRS3,EDN1,GHRL,HAPLN3,LRP5,MAF,MMP9,P2RX7,PTGER4,SCIN,SGPL1,SNX10,TGM2,TIFAB,TMEM119,TYMS,VCAN,XYLT1"} {"GO.ID":"GO:0014033","Term":"neural crest cell differentiation","Annotated":77,"Significant":4,"Expected":4.65,"Rank in p.value_classic":3649,"p.value_elim":0.68952,"p.value_classic":0.69146,"genes":"EDN1,KITLG,NRP1,SEMA6B"} {"GO.ID":"GO:0000266","Term":"mitochondrial fission","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3650,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"LRRK2,STAT2"} {"GO.ID":"GO:0006904","Term":"vesicle docking involved in exocytosis","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3651,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"PLEK,RALB"} {"GO.ID":"GO:0030835","Term":"negative regulation of actin filament depolymerization","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3652,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"SCIN,SPTBN4"} {"GO.ID":"GO:0050873","Term":"brown fat cell differentiation","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3653,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"LAMB3,PIM1"} {"GO.ID":"GO:1900271","Term":"regulation of long-term synaptic potentiation","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3654,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"CX3CR1,FAM107A"} {"GO.ID":"GO:0071364","Term":"cellular response to epidermal growth factor stimulus","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3655,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"DAB2,GAREM1"} {"GO.ID":"GO:0071320","Term":"cellular response to cAMP","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3656,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"CRHBP,RAPGEF2"} {"GO.ID":"GO:0021795","Term":"cerebral cortex cell migration","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3657,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"DAB1,MDGA1"} {"GO.ID":"GO:1903146","Term":"regulation of autophagy of mitochondrion","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3658,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"ATP13A2,NOD2"} {"GO.ID":"GO:0072595","Term":"maintenance of protein localization in organelle","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3659,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"PML,SYNE1"} {"GO.ID":"GO:0045214","Term":"sarcomere organization","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3660,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"EDN1,MYOZ2"} {"GO.ID":"GO:0045747","Term":"positive regulation of Notch signaling pathway","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3661,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"DLL1,NOD2"} {"GO.ID":"GO:0071604","Term":"transforming growth factor beta production","Annotated":39,"Significant":2,"Expected":2.36,"Rank in p.value_classic":3662,"p.value_elim":0.69021,"p.value_classic":0.69157,"genes":"ADAM8,AGT"} {"GO.ID":"GO:0042100","Term":"B cell proliferation","Annotated":72,"Significant":10,"Expected":4.35,"Rank in p.value_classic":766,"p.value_elim":0.69037,"p.value_classic":0.01091,"genes":"BCL6,CD38,CD40,CD74,CTLA4,GPR183,IL7,LYN,TNFRSF21,TNFSF13B"} {"GO.ID":"GO:0099504","Term":"synaptic vesicle cycle","Annotated":169,"Significant":13,"Expected":10.21,"Rank in p.value_classic":1938,"p.value_elim":0.69083,"p.value_classic":0.22163,"genes":"CADPS2,DNM1,DTNBP1,ERC2,ITSN1,LRRK2,P2RX7,PRRT2,SLC18A1,STX11,STX1A,SV2B,SYT1"} {"GO.ID":"GO:0043405","Term":"regulation of MAP kinase activity","Annotated":114,"Significant":6,"Expected":6.89,"Rank in p.value_classic":3665,"p.value_elim":0.69085,"p.value_classic":0.69321,"genes":"AGT,CD40,EDN1,LRRK2,LYN,TNFRSF11A"} {"GO.ID":"GO:1905039","Term":"carboxylic acid transmembrane transport","Annotated":114,"Significant":6,"Expected":6.89,"Rank in p.value_classic":3666,"p.value_elim":0.69085,"p.value_classic":0.69321,"genes":"ABCB1,ACSL1,KCNJ10,SLC11A1,SLC16A10,SLC6A12"} {"GO.ID":"GO:0002685","Term":"regulation of leukocyte migration","Annotated":191,"Significant":29,"Expected":11.54,"Rank in p.value_classic":265,"p.value_elim":0.69111,"p.value_classic":3.9e-06,"genes":"ADAM8,ASCL2,CCL5,CCL7,CCL8,CD74,CSF1,CX3CR1,CXCL10,CXCR3,EDN1,ICAM1,IL12A,KITLG,KLRK1,LYN,LYVE1,MTUS1,NOD2,P2RX4,PADI2,PTGER4,SLAMF1,SLAMF8,STAP1,TNFAIP6,TNFRSF14,TNFSF18,VEGFC"} {"GO.ID":"GO:0006662","Term":"glycerol ether metabolic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3667,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"PLAAT3"} {"GO.ID":"GO:0045649","Term":"regulation of macrophage differentiation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3668,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"CSF1"} {"GO.ID":"GO:0045606","Term":"positive regulation of epidermal cell differentiation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3669,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"PLAAT4"} {"GO.ID":"GO:0140354","Term":"lipid import into cell","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3670,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"ACSL1"} {"GO.ID":"GO:0034377","Term":"plasma lipoprotein particle assembly","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3671,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"SOAT1"} {"GO.ID":"GO:0090201","Term":"negative regulation of release of cytochrome c from mitochondria","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3672,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"HGF"} {"GO.ID":"GO:0010888","Term":"negative regulation of lipid storage","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3673,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"TTC39B"} {"GO.ID":"GO:0060216","Term":"definitive hemopoiesis","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3674,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"TAL1"} {"GO.ID":"GO:0061099","Term":"negative regulation of protein tyrosine kinase activity","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3675,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"MVP"} {"GO.ID":"GO:1990182","Term":"exosomal secretion","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3676,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"ATP13A2"} {"GO.ID":"GO:0016075","Term":"rRNA catabolic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3677,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"XRN1"} {"GO.ID":"GO:1900227","Term":"positive regulation of NLRP3 inflammasome complex assembly","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3678,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"GBP5"} {"GO.ID":"GO:0097049","Term":"motor neuron apoptotic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3679,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"FAS"} {"GO.ID":"GO:0035089","Term":"establishment of apical/basal cell polarity","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3680,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"FSCN1"} {"GO.ID":"GO:0072311","Term":"glomerular epithelial cell differentiation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3681,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"EDN1"} {"GO.ID":"GO:2000434","Term":"regulation of protein neddylation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3682,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"EPAS1"} {"GO.ID":"GO:0061318","Term":"renal filtration cell differentiation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3683,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"EDN1"} {"GO.ID":"GO:2000178","Term":"negative regulation of neural precursor cell proliferation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3684,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"APPL2"} {"GO.ID":"GO:0071305","Term":"cellular response to vitamin D","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3685,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"PIM1"} {"GO.ID":"GO:0038128","Term":"ERBB2 signaling pathway","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3686,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"HBEGF"} {"GO.ID":"GO:0072111","Term":"cell proliferation involved in kidney development","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3687,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"STAT1"} {"GO.ID":"GO:0072112","Term":"podocyte differentiation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3688,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"EDN1"} {"GO.ID":"GO:0036499","Term":"PERK-mediated unfolded protein response","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3689,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"AGR2"} {"GO.ID":"GO:0061158","Term":"3'-UTR-mediated mRNA destabilization","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3690,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"ZC3H12A"} {"GO.ID":"GO:2000786","Term":"positive regulation of autophagosome assembly","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3691,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"RALB"} {"GO.ID":"GO:0046485","Term":"ether lipid metabolic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3692,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"PLAAT3"} {"GO.ID":"GO:1901385","Term":"regulation of voltage-gated calcium channel activity","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3693,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"SRI"} {"GO.ID":"GO:0072207","Term":"metanephric epithelium development","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3694,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"STAT1"} {"GO.ID":"GO:0048791","Term":"calcium ion-regulated exocytosis of neurotransmitter","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3695,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"SYT1"} {"GO.ID":"GO:0007202","Term":"activation of phospholipase C activity","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3696,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"ITK"} {"GO.ID":"GO:0021697","Term":"cerebellar cortex formation","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3697,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"DLL1"} {"GO.ID":"GO:2000641","Term":"regulation of early endosome to late endosome transport","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3698,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"DAB2"} {"GO.ID":"GO:0046716","Term":"muscle cell cellular homeostasis","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3699,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"ANKH"} {"GO.ID":"GO:0048670","Term":"regulation of collateral sprouting","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3700,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"FSTL4"} {"GO.ID":"GO:1903579","Term":"negative regulation of ATP metabolic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3701,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"PID1"} {"GO.ID":"GO:0046519","Term":"sphingoid metabolic process","Annotated":19,"Significant":1,"Expected":1.15,"Rank in p.value_classic":3702,"p.value_elim":0.69314,"p.value_classic":0.69409,"genes":"NAAA"} {"GO.ID":"GO:0015918","Term":"sterol transport","Annotated":96,"Significant":5,"Expected":5.8,"Rank in p.value_classic":3703,"p.value_elim":0.69378,"p.value_classic":0.69594,"genes":"EEPD1,GRAMD1B,OSBPL6,SOAT1,TTC39B"} {"GO.ID":"GO:0007368","Term":"determination of left/right symmetry","Annotated":96,"Significant":5,"Expected":5.8,"Rank in p.value_classic":3704,"p.value_elim":0.69378,"p.value_classic":0.69594,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0016192","Term":"vesicle-mediated transport","Annotated":1355,"Significant":91,"Expected":81.84,"Rank in p.value_classic":1649,"p.value_elim":0.69558,"p.value_classic":0.14856,"genes":"ANK2,APPL2,ARL4C,ATP13A2,B2M,C2,C3,C4A,C4B,CADPS2,CCL5,CCL8,CD163,CD300LF,CD93,CEACAM1,CHMP4C,CLEC10A,CLEC9A,COLEC12,CRHBP,CTSL,DAB2,DLL1,DNM1,DOP1A,DTNBP1,DTX3L,DYSF,ENPP2,ERC2,EXOC3L1,EXOC3L4,FCN1,HAVCR1,HLA-F,IGF2R,IL15,IL15RA,ITSN1,LGALS3BP,LMTK2,LRP5,LRRK2,LY75,LYN,LYVE1,MERTK,MYO7B,NECAB2,NOD2,NR4A3,NRP1,OPTN,P2RX7,PLEK,PLPP4,PLSCR1,PRRT2,RAB20,RALB,REPS2,RHOBTB3,S100A10,S100A13,SCARF1,SCIN,SEPTIN4,SLAMF1,SLC11A1,SLC18A1,SNX10,SPTBN4,STAP1,STX11,STX1A,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAPBP,TGM2,TICAM2,TNFAIP2,TPCN1,TYRO3,USP6NL,VAMP5,VPS9D1,XKR6"} {"GO.ID":"GO:0072659","Term":"protein localization to plasma membrane","Annotated":258,"Significant":14,"Expected":15.58,"Rank in p.value_classic":3708,"p.value_elim":0.69593,"p.value_classic":0.69949,"genes":"AGR2,ANK2,DAB2,FYB1,GBP1,OPTN,PID1,RAPGEF2,S100A10,SPTBN4,TESC,TMEM150A,TSPAN15,VAMP5"} {"GO.ID":"GO:0002064","Term":"epithelial cell development","Annotated":169,"Significant":9,"Expected":10.21,"Rank in p.value_classic":3706,"p.value_elim":0.69609,"p.value_classic":0.69896,"genes":"CDH5,DLL1,EPAS1,ICAM1,MARVELD2,ONECUT2,RAPGEF2,SIDT2,TYMS"} {"GO.ID":"GO:0032869","Term":"cellular response to insulin stimulus","Annotated":169,"Significant":9,"Expected":10.21,"Rank in p.value_classic":3707,"p.value_elim":0.69609,"p.value_classic":0.69896,"genes":"APPL2,CEACAM1,PDE3B,PDK4,PID1,PNPLA3,SESN3,SOCS1,STAT1"} {"GO.ID":"GO:0009952","Term":"anterior/posterior pattern specification","Annotated":151,"Significant":8,"Expected":9.12,"Rank in p.value_classic":3705,"p.value_elim":0.69617,"p.value_classic":0.69888,"genes":"BHLHE41,DLL1,LRP5,PLXNA2,SOX17,SSBP3,TIFAB,XRCC2"} {"GO.ID":"GO:0031396","Term":"regulation of protein ubiquitination","Annotated":187,"Significant":10,"Expected":11.29,"Rank in p.value_classic":3709,"p.value_elim":0.69655,"p.value_classic":0.69956,"genes":"AMER1,DTX3L,FAM107A,LRRK2,MAD2L1,NMI,NOD2,PARP10,RIPK2,SEPTIN4"} {"GO.ID":"GO:0099003","Term":"vesicle-mediated transport in synapse","Annotated":188,"Significant":14,"Expected":11.35,"Rank in p.value_classic":2016,"p.value_elim":0.6971,"p.value_classic":0.24616,"genes":"CADPS2,DNM1,DTNBP1,ERC2,ITSN1,LRRK2,P2RX7,PRRT2,SLC18A1,STX11,STX1A,SV2B,SYNE1,SYT1"} {"GO.ID":"GO:0010628","Term":"positive regulation of gene expression","Annotated":946,"Significant":97,"Expected":57.13,"Rank in p.value_classic":185,"p.value_elim":0.69784,"p.value_classic":1.2e-07,"genes":"ADAM8,AGR2,AGT,AIM2,ANK2,ATF3,ATP13A2,B2M,BRCA1,BTN3A1,BTN3A2,C3,CCL5,CD274,CD28,CD74,CD80,CD83,CDH5,CDK1,CLEC6A,CLEC9A,CSF1,DAZL,DLL1,DTNBP1,E2F1,EDA,FCN1,GBP5,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KLF4,KLRK1,LAMP3,LILRA2,LPL,LRRK2,LTA,MAF,MCOLN2,MEFV,NLRP12,NOD2,NR4A3,OAS2,OAS3,OSM,P2RX7,PADI2,PDE4B,PID1,PLSCR1,PTGER4,RIPK2,RSAD2,S100A10,S100A13,SAMD4A,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOX17,STAP1,STAT1,TANK,TBX21,TESC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF14,WARS1,ZC3H12A"} {"GO.ID":"GO:0045661","Term":"regulation of myoblast differentiation","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3710,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"CXCL10,CXCL9,DLL1"} {"GO.ID":"GO:0034394","Term":"protein localization to cell surface","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3711,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"ANK2,FCN1,PTPRU"} {"GO.ID":"GO:0002011","Term":"morphogenesis of an epithelial sheet","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3712,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"CEACAM1,HBEGF,ITGB5"} {"GO.ID":"GO:0097352","Term":"autophagosome maturation","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3713,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"CALCOCO2,CHMP4C,MAP1LC3C"} {"GO.ID":"GO:0043954","Term":"cellular component maintenance","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3714,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"CBLN3,ERC2,MTSS1"} {"GO.ID":"GO:1903578","Term":"regulation of ATP metabolic process","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3715,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"P2RX7,PID1,SLC2A6"} {"GO.ID":"GO:0046847","Term":"filopodium assembly","Annotated":59,"Significant":3,"Expected":3.56,"Rank in p.value_classic":3716,"p.value_elim":0.69842,"p.value_classic":0.70009,"genes":"FGD5,FSCN1,NRP1"} {"GO.ID":"GO:0045017","Term":"glycerolipid biosynthetic process","Annotated":223,"Significant":12,"Expected":13.47,"Rank in p.value_classic":3722,"p.value_elim":0.69851,"p.value_classic":0.7018,"genes":"ACSL1,C3,CDS1,CISH,DGAT2,GK,LCLAT1,PCYT1A,PLSCR1,PNPLA3,SOCS1,TMEM150A"} {"GO.ID":"GO:0001936","Term":"regulation of endothelial cell proliferation","Annotated":115,"Significant":6,"Expected":6.95,"Rank in p.value_classic":3719,"p.value_elim":0.69891,"p.value_classic":0.70125,"genes":"GHRL,IL12A,MIR503,NRP1,STAT1,VEGFC"} {"GO.ID":"GO:0007043","Term":"cell-cell junction assembly","Annotated":115,"Significant":6,"Expected":6.95,"Rank in p.value_classic":3720,"p.value_elim":0.69891,"p.value_classic":0.70125,"genes":"AGT,ANK2,CDH5,FSCN1,GJD3,MARVELD2"} {"GO.ID":"GO:1903825","Term":"organic acid transmembrane transport","Annotated":115,"Significant":6,"Expected":6.95,"Rank in p.value_classic":3721,"p.value_elim":0.69891,"p.value_classic":0.70125,"genes":"ABCB1,ACSL1,KCNJ10,SLC11A1,SLC16A10,SLC6A12"} {"GO.ID":"GO:0008585","Term":"female gonad development","Annotated":78,"Significant":4,"Expected":4.71,"Rank in p.value_classic":3717,"p.value_elim":0.69925,"p.value_classic":0.70117,"genes":"DMC1,KITLG,SGPL1,TNFAIP6"} {"GO.ID":"GO:1903510","Term":"mucopolysaccharide metabolic process","Annotated":78,"Significant":4,"Expected":4.71,"Rank in p.value_classic":3718,"p.value_elim":0.69925,"p.value_classic":0.70117,"genes":"DSE,LYVE1,TNFAIP6,XYLT1"} {"GO.ID":"GO:0007416","Term":"synapse assembly","Annotated":152,"Significant":8,"Expected":9.18,"Rank in p.value_classic":3731,"p.value_elim":0.70316,"p.value_classic":0.70584,"genes":"COLQ,EPHB3,GABRA3,GHRL,LGI2,MDGA1,NRCAM,THBS2"} {"GO.ID":"GO:0170040","Term":"proteinogenic amino acid catabolic process","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3723,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"GLUL,IL4I1"} {"GO.ID":"GO:0060236","Term":"regulation of mitotic spindle organization","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3724,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"CHMP4C,PARP3"} {"GO.ID":"GO:0030517","Term":"negative regulation of axon extension","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3725,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"NRP1,SEMA6B"} {"GO.ID":"GO:0032387","Term":"negative regulation of intracellular transport","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3726,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"DERL3,LRRK2"} {"GO.ID":"GO:0030501","Term":"positive regulation of bone mineralization","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3727,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"P2RX7,TMEM119"} {"GO.ID":"GO:0007099","Term":"centriole replication","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3728,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"BRCA1,WDR62"} {"GO.ID":"GO:0021575","Term":"hindbrain morphogenesis","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3729,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"DAB1,DLL1"} {"GO.ID":"GO:0015804","Term":"neutral amino acid transport","Annotated":40,"Significant":2,"Expected":2.42,"Rank in p.value_classic":3730,"p.value_elim":0.70357,"p.value_classic":0.70492,"genes":"CTNS,SERINC5"} {"GO.ID":"GO:0007517","Term":"muscle organ development","Annotated":278,"Significant":15,"Expected":16.79,"Rank in p.value_classic":3740,"p.value_elim":0.70815,"p.value_classic":0.71178,"genes":"ASB2,ATF3,CENPF,CXCL10,DLL1,EGR2,HBEGF,ITGA7,ITGB1BP2,MAFF,MYOZ2,S1PR1,SRI,TIFAB,VAMP5"} {"GO.ID":"GO:0010833","Term":"telomere maintenance via telomere lengthening","Annotated":79,"Significant":4,"Expected":4.77,"Rank in p.value_classic":3733,"p.value_elim":0.70875,"p.value_classic":0.71065,"genes":"AURKB,GCH1,PKIB,XRN1"} {"GO.ID":"GO:0046545","Term":"development of primary female sexual characteristics","Annotated":79,"Significant":4,"Expected":4.77,"Rank in p.value_classic":3734,"p.value_elim":0.70875,"p.value_classic":0.71065,"genes":"DMC1,KITLG,SGPL1,TNFAIP6"} {"GO.ID":"GO:0090109","Term":"regulation of cell-substrate junction assembly","Annotated":60,"Significant":3,"Expected":3.62,"Rank in p.value_classic":3735,"p.value_elim":0.70928,"p.value_classic":0.71092,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:0009953","Term":"dorsal/ventral pattern formation","Annotated":60,"Significant":3,"Expected":3.62,"Rank in p.value_classic":3736,"p.value_elim":0.70928,"p.value_classic":0.71092,"genes":"CHRD,EDN1,IFT122"} {"GO.ID":"GO:0051893","Term":"regulation of focal adhesion assembly","Annotated":60,"Significant":3,"Expected":3.62,"Rank in p.value_classic":3737,"p.value_elim":0.70928,"p.value_classic":0.71092,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:0046854","Term":"phosphatidylinositol phosphate biosynthetic process","Annotated":60,"Significant":3,"Expected":3.62,"Rank in p.value_classic":3738,"p.value_elim":0.70928,"p.value_classic":0.71092,"genes":"CISH,SOCS1,TMEM150A"} {"GO.ID":"GO:0035567","Term":"non-canonical Wnt signaling pathway","Annotated":60,"Significant":3,"Expected":3.62,"Rank in p.value_classic":3739,"p.value_elim":0.70928,"p.value_classic":0.71092,"genes":"CELSR1,DAB2,RNF213"} {"GO.ID":"GO:0007548","Term":"sex differentiation","Annotated":207,"Significant":11,"Expected":12.5,"Rank in p.value_classic":3741,"p.value_elim":0.70937,"p.value_classic":0.71248,"genes":"BCL2L11,DMC1,HESX1,KITLG,MERTK,RHOBTB3,SGPL1,TIFAB,TNFAIP6,TNFSF10,TYRO3"} {"GO.ID":"GO:0090066","Term":"regulation of anatomical structure size","Annotated":419,"Significant":23,"Expected":25.31,"Rank in p.value_classic":3788,"p.value_elim":0.70971,"p.value_classic":0.71419,"genes":"AGT,ATP13A2,CD38,COMP,CYSLTR1,DEPTOR,DNM1,EDN1,FSTL4,GCH1,HRH2,IQGAP3,LRRK2,NPR1,NRCAM,NRP1,P2RX7,PLEK,SCIN,SEMA6B,SLC12A3,SPTBN4,TMSB10"} {"GO.ID":"GO:0051146","Term":"striated muscle cell differentiation","Annotated":243,"Significant":13,"Expected":14.68,"Rank in p.value_classic":3789,"p.value_elim":0.7109,"p.value_classic":0.71427,"genes":"ADAMTS15,ASB2,BHLHE41,CASP7,CDK1,CXADR,CXCL10,CXCL9,DLL1,EDN1,MYOZ2,SYNE1,TMEM119"} {"GO.ID":"GO:1905146","Term":"lysosomal protein catabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3742,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"ATP13A2"} {"GO.ID":"GO:0033081","Term":"regulation of T cell differentiation in thymus","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3743,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"ADAM8"} {"GO.ID":"GO:0039702","Term":"viral budding via host ESCRT complex","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3744,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"CHMP4C"} {"GO.ID":"GO:0002092","Term":"positive regulation of receptor internalization","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3745,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"DTNBP1"} {"GO.ID":"GO:0060117","Term":"auditory receptor cell development","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3746,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"SLC4A7"} {"GO.ID":"GO:0060143","Term":"positive regulation of syncytium formation by plasma membrane fusion","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3747,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"CXCL9"} {"GO.ID":"GO:0035994","Term":"response to muscle stretch","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3748,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"EDN1"} {"GO.ID":"GO:0035988","Term":"chondrocyte proliferation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3749,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"COMP"} {"GO.ID":"GO:0045980","Term":"negative regulation of nucleotide metabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3750,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"PID1"} {"GO.ID":"GO:0006907","Term":"pinocytosis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3751,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"APPL2"} {"GO.ID":"GO:0045940","Term":"positive regulation of steroid metabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3752,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"DAB2"} {"GO.ID":"GO:0010839","Term":"negative regulation of keratinocyte proliferation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3753,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"OVOL1"} {"GO.ID":"GO:0043302","Term":"positive regulation of leukocyte degranulation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3754,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"HLA-F"} {"GO.ID":"GO:0061049","Term":"cell growth involved in cardiac muscle cell development","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3755,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"EDN1"} {"GO.ID":"GO:0003301","Term":"physiological cardiac muscle hypertrophy","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3756,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"EDN1"} {"GO.ID":"GO:0018394","Term":"peptidyl-lysine acetylation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3757,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"PML"} {"GO.ID":"GO:0060575","Term":"intestinal epithelial cell differentiation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3758,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"TYMS"} {"GO.ID":"GO:0044794","Term":"positive regulation by host of viral process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3759,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"IGF2R"} {"GO.ID":"GO:0003148","Term":"outflow tract septum morphogenesis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3760,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"NRP1"} {"GO.ID":"GO:0006027","Term":"glycosaminoglycan catabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3761,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"LYVE1"} {"GO.ID":"GO:0032104","Term":"regulation of response to extracellular stimulus","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3762,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"GHRL"} {"GO.ID":"GO:0032107","Term":"regulation of response to nutrient levels","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3763,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"GHRL"} {"GO.ID":"GO:0003298","Term":"physiological muscle hypertrophy","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3764,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"EDN1"} {"GO.ID":"GO:0006007","Term":"glucose catabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3765,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"LRP5"} {"GO.ID":"GO:0032288","Term":"myelin assembly","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3766,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"ANK2"} {"GO.ID":"GO:0008334","Term":"histone mRNA metabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3767,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"XRN1"} {"GO.ID":"GO:0051450","Term":"myoblast proliferation","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3768,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"HGF"} {"GO.ID":"GO:0061484","Term":"hematopoietic stem cell homeostasis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3769,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"SEPTIN4"} {"GO.ID":"GO:0042755","Term":"eating behavior","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3770,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"GHRL"} {"GO.ID":"GO:0036315","Term":"cellular response to sterol","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3771,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"GRAMD1B"} {"GO.ID":"GO:0036344","Term":"platelet morphogenesis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3772,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"TAL1"} {"GO.ID":"GO:1900543","Term":"negative regulation of purine nucleotide metabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3773,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"PID1"} {"GO.ID":"GO:0036303","Term":"lymph vessel morphogenesis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3774,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"VEGFC"} {"GO.ID":"GO:0021756","Term":"striatum development","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3775,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"LRRK2"} {"GO.ID":"GO:0097494","Term":"regulation of vesicle size","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3776,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"DNM1"} {"GO.ID":"GO:0072273","Term":"metanephric nephron morphogenesis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3777,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"STAT1"} {"GO.ID":"GO:0036120","Term":"cellular response to platelet-derived growth factor stimulus","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3778,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"CCNA2"} {"GO.ID":"GO:0071786","Term":"endoplasmic reticulum tubular network organization","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3779,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"REEP1"} {"GO.ID":"GO:0099010","Term":"modification of postsynaptic structure","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3780,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"CTTNBP2"} {"GO.ID":"GO:1903859","Term":"regulation of dendrite extension","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3781,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"SYT1"} {"GO.ID":"GO:0097734","Term":"extracellular exosome biogenesis","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3782,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"ATP13A2"} {"GO.ID":"GO:0048665","Term":"neuron fate specification","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3783,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"DLL1"} {"GO.ID":"GO:0006743","Term":"ubiquinone metabolic process","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3784,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"AIFM2"} {"GO.ID":"GO:0007602","Term":"phototransduction","Annotated":20,"Significant":1,"Expected":1.21,"Rank in p.value_classic":3785,"p.value_elim":0.71166,"p.value_classic":0.71259,"genes":"CDS1"} {"GO.ID":"GO:0048754","Term":"branching morphogenesis of an epithelial tube","Annotated":135,"Significant":7,"Expected":8.15,"Rank in p.value_classic":3787,"p.value_elim":0.7117,"p.value_classic":0.71419,"genes":"AGT,CELSR1,CSF1,EDN1,LRP5,NRP1,PML"} {"GO.ID":"GO:0010506","Term":"regulation of autophagy","Annotated":332,"Significant":18,"Expected":20.05,"Rank in p.value_classic":3790,"p.value_elim":0.71307,"p.value_classic":0.71701,"genes":"ATP13A2,ATP6V0D2,CALCOCO2,DEPTOR,DRAM1,HGF,LAMP3,LRRK2,MEFV,NOD2,OPTN,RALB,RIPK2,RUFY4,SESN3,TPCN1,TRIM22,ZC3H12A"} {"GO.ID":"GO:1901698","Term":"response to nitrogen compound","Annotated":891,"Significant":59,"Expected":53.81,"Rank in p.value_classic":2015,"p.value_elim":0.71328,"p.value_classic":0.24424,"genes":"AGT,APPL2,ASIC1,BRCA1,CASP4,CASP7,CASTOR1,CCNA2,CD40,CDC6,CDK1,CEACAM1,COLEC12,CRHBP,DERL3,DHFR,DTNBP1,EDN1,EGR2,FBXO6,GHRL,GNG2,ICAM1,IFIH1,JAK2,JAK3,KLF4,LPL,LRP5,LRRK2,LYN,MMP9,NOD2,NR4A3,P2RX4,P2RX7,PDE3B,PDK4,PID1,PMAIP1,PNPLA3,PXN,RALB,RAPGEF2,RIPK2,SESN3,SOCS1,STAMBPL1,STAT1,STAT2,TGM2,THBD,TICAM2,TLR7,TNFRSF11A,TNFSF10,TYMS,VCAM1,XRN1"} {"GO.ID":"GO:1902991","Term":"regulation of amyloid precursor protein catabolic process","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3791,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"GSAP,LYN"} {"GO.ID":"GO:0010517","Term":"regulation of phospholipase activity","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3792,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"CCL5,ITK"} {"GO.ID":"GO:0061001","Term":"regulation of dendritic spine morphogenesis","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3793,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"DTNBP1,LRRK2"} {"GO.ID":"GO:0043407","Term":"negative regulation of MAP kinase activity","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3794,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"AGT,LYN"} {"GO.ID":"GO:0007019","Term":"microtubule depolymerization","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3795,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"KIF18B,STMN1"} {"GO.ID":"GO:0006418","Term":"tRNA aminoacylation for protein translation","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3796,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"KARS1,WARS1"} {"GO.ID":"GO:0051205","Term":"protein insertion into membrane","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3797,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"REEP1,RTP4"} {"GO.ID":"GO:1903214","Term":"regulation of protein targeting to mitochondrion","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3798,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0036297","Term":"interstrand cross-link repair","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3799,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"FANCE,NEIL3"} {"GO.ID":"GO:0031670","Term":"cellular response to nutrient","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3800,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"LPL,PIM1"} {"GO.ID":"GO:0009395","Term":"phospholipid catabolic process","Annotated":41,"Significant":2,"Expected":2.48,"Rank in p.value_classic":3801,"p.value_elim":0.71646,"p.value_classic":0.71779,"genes":"ENPP2,PLB1"} {"GO.ID":"GO:1905897","Term":"regulation of response to endoplasmic reticulum stress","Annotated":80,"Significant":4,"Expected":4.83,"Rank in p.value_classic":3802,"p.value_elim":0.71804,"p.value_classic":0.71992,"genes":"AGR2,BCL2L11,LRRK2,PMAIP1"} {"GO.ID":"GO:0046496","Term":"nicotinamide nucleotide metabolic process","Annotated":136,"Significant":7,"Expected":8.21,"Rank in p.value_classic":3803,"p.value_elim":0.71888,"p.value_classic":0.72134,"genes":"CD38,IDO1,IDO2,P2RX7,PARP10,PARP9,SLC2A6"} {"GO.ID":"GO:0019362","Term":"pyridine nucleotide metabolic process","Annotated":136,"Significant":7,"Expected":8.21,"Rank in p.value_classic":3804,"p.value_elim":0.71888,"p.value_classic":0.72134,"genes":"CD38,IDO1,IDO2,P2RX7,PARP10,PARP9,SLC2A6"} {"GO.ID":"GO:0019080","Term":"viral gene expression","Annotated":99,"Significant":5,"Expected":5.98,"Rank in p.value_classic":3806,"p.value_elim":0.71937,"p.value_classic":0.72145,"genes":"CCL5,IFITM3,PARP10,PARP9,TRIM31"} {"GO.ID":"GO:0014902","Term":"myotube differentiation","Annotated":99,"Significant":5,"Expected":5.98,"Rank in p.value_classic":3807,"p.value_elim":0.71937,"p.value_classic":0.72145,"genes":"ADAMTS15,BHLHE41,CXCL10,CXCL9,TMEM119"} {"GO.ID":"GO:0032956","Term":"regulation of actin cytoskeleton organization","Annotated":298,"Significant":16,"Expected":18,"Rank in p.value_classic":3808,"p.value_elim":0.71958,"p.value_classic":0.72326,"genes":"CELSR1,EDN1,FAM107A,FSCN1,MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:2000630","Term":"positive regulation of miRNA metabolic process","Annotated":61,"Significant":3,"Expected":3.68,"Rank in p.value_classic":3805,"p.value_elim":0.71983,"p.value_classic":0.72145,"genes":"AGT,KLF4,ZC3H12A"} {"GO.ID":"GO:0008610","Term":"lipid biosynthetic process","Annotated":579,"Significant":32,"Expected":34.97,"Rank in p.value_classic":3813,"p.value_elim":0.72193,"p.value_classic":0.72712,"genes":"ACOT4,ACSL1,BRCA1,C3,CD74,CDS1,CEACAM1,CISH,CYP1A1,DAB2,DGAT2,DHRS9,EDN1,FAXDC2,GAL3ST4,GGT5,GK,HSD3B7,LCLAT1,LPL,LTC4S,OSBPL6,P2RX7,PCYT1A,PDK4,PLAAT3,PLSCR1,PNPLA3,SERINC5,SLC45A3,SOCS1,TMEM150A"} {"GO.ID":"GO:0051053","Term":"negative regulation of DNA metabolic process","Annotated":118,"Significant":6,"Expected":7.13,"Rank in p.value_classic":3810,"p.value_elim":0.72224,"p.value_classic":0.72451,"genes":"BCL6,CDC6,CDT1,PARP3,RMI2,XRN1"} {"GO.ID":"GO:0017148","Term":"negative regulation of translation","Annotated":118,"Significant":6,"Expected":7.13,"Rank in p.value_classic":3811,"p.value_elim":0.72224,"p.value_classic":0.72451,"genes":"BANK1,DHFR,MIR503,SAMD4A,TYMS,XRN1"} {"GO.ID":"GO:1905517","Term":"macrophage migration","Annotated":50,"Significant":9,"Expected":3.02,"Rank in p.value_classic":584,"p.value_elim":0.72614,"p.value_classic":0.00273,"genes":"CCL5,CSF1,CX3CR1,MCOLN2,MTUS1,P2RX4,SLAMF1,SLAMF8,STAP1"} {"GO.ID":"GO:2001234","Term":"negative regulation of apoptotic signaling pathway","Annotated":210,"Significant":11,"Expected":12.68,"Rank in p.value_classic":3820,"p.value_elim":0.72679,"p.value_classic":0.72982,"genes":"BRCA1,CD74,CX3CR1,HELLS,HGF,ICAM1,IL7,LRRK2,MMP9,MUC1,NRP1"} {"GO.ID":"GO:0006637","Term":"acyl-CoA metabolic process","Annotated":81,"Significant":4,"Expected":4.89,"Rank in p.value_classic":3814,"p.value_elim":0.72711,"p.value_classic":0.72896,"genes":"ACOT4,ACSL1,DGAT2,PDK4"} {"GO.ID":"GO:0014812","Term":"muscle cell migration","Annotated":81,"Significant":4,"Expected":4.89,"Rank in p.value_classic":3815,"p.value_elim":0.72711,"p.value_classic":0.72896,"genes":"CCL5,MIR503,NR4A3,NRP1"} {"GO.ID":"GO:0007338","Term":"single fertilization","Annotated":81,"Significant":4,"Expected":4.89,"Rank in p.value_classic":3816,"p.value_elim":0.72711,"p.value_classic":0.72896,"genes":"CDK1,NPM2,PLB1,SYT6"} {"GO.ID":"GO:0035383","Term":"thioester metabolic process","Annotated":81,"Significant":4,"Expected":4.89,"Rank in p.value_classic":3817,"p.value_elim":0.72711,"p.value_classic":0.72896,"genes":"ACOT4,ACSL1,DGAT2,PDK4"} {"GO.ID":"GO:2001243","Term":"negative regulation of intrinsic apoptotic signaling pathway","Annotated":100,"Significant":5,"Expected":6.04,"Rank in p.value_classic":3819,"p.value_elim":0.72755,"p.value_classic":0.72961,"genes":"CD74,HELLS,LRRK2,MMP9,MUC1"} {"GO.ID":"GO:0030811","Term":"regulation of nucleotide catabolic process","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3843,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0033121","Term":"regulation of purine nucleotide catabolic process","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3844,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0035384","Term":"thioester biosynthetic process","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3845,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"ACSL1,PDK4"} {"GO.ID":"GO:0006110","Term":"regulation of glycolytic process","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3846,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0071616","Term":"acyl-CoA biosynthetic process","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3847,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"ACSL1,PDK4"} {"GO.ID":"GO:0120009","Term":"intermembrane lipid transfer","Annotated":42,"Significant":2,"Expected":2.54,"Rank in p.value_classic":3848,"p.value_elim":0.72886,"p.value_classic":0.73018,"genes":"GRAMD1B,TNFAIP8L3"} {"GO.ID":"GO:0045686","Term":"negative regulation of glial cell differentiation","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3821,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"DAB1"} {"GO.ID":"GO:1901673","Term":"regulation of mitotic spindle assembly","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3822,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"CHMP4C"} {"GO.ID":"GO:0010875","Term":"positive regulation of cholesterol efflux","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3823,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"EEPD1"} {"GO.ID":"GO:1901983","Term":"regulation of protein acetylation","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3824,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"PML"} {"GO.ID":"GO:0140239","Term":"postsynaptic endocytosis","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3825,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"SYNE1"} {"GO.ID":"GO:0046033","Term":"AMP metabolic process","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3826,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"AK1"} {"GO.ID":"GO:1902018","Term":"negative regulation of cilium assembly","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3827,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"LIMK2"} {"GO.ID":"GO:0043267","Term":"negative regulation of potassium ion transport","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3828,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"KCNE5"} {"GO.ID":"GO:0032252","Term":"secretory granule localization","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3829,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"CADPS2"} {"GO.ID":"GO:0032211","Term":"negative regulation of telomere maintenance via telomerase","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3830,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"XRN1"} {"GO.ID":"GO:0048169","Term":"regulation of long-term neuronal synaptic plasticity","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3831,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"KCNJ10"} {"GO.ID":"GO:0065005","Term":"protein-lipid complex assembly","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3832,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"SOAT1"} {"GO.ID":"GO:2000209","Term":"regulation of anoikis","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3833,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"PDK4"} {"GO.ID":"GO:0061162","Term":"establishment of monopolar cell polarity","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3834,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"FSCN1"} {"GO.ID":"GO:0070935","Term":"3'-UTR-mediated mRNA stabilization","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3835,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"DAZL"} {"GO.ID":"GO:1904706","Term":"negative regulation of vascular associated smooth muscle cell proliferation","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3836,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"MIR503"} {"GO.ID":"GO:0098780","Term":"response to mitochondrial depolarisation","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3837,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"OPTN"} {"GO.ID":"GO:0098884","Term":"postsynaptic neurotransmitter receptor internalization","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3838,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"SYNE1"} {"GO.ID":"GO:0035278","Term":"miRNA-mediated gene silencing by inhibition of translation","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3839,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"MIR503"} {"GO.ID":"GO:0090050","Term":"positive regulation of cell migration involved in sprouting angiogenesis","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3840,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"NRP1"} {"GO.ID":"GO:0046885","Term":"regulation of hormone biosynthetic process","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3841,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"DAB2"} {"GO.ID":"GO:0032958","Term":"inositol phosphate biosynthetic process","Annotated":21,"Significant":1,"Expected":1.27,"Rank in p.value_classic":3842,"p.value_elim":0.72905,"p.value_classic":0.72998,"genes":"PLEK"} {"GO.ID":"GO:0033143","Term":"regulation of intracellular steroid hormone receptor signaling pathway","Annotated":62,"Significant":3,"Expected":3.74,"Rank in p.value_classic":3849,"p.value_elim":0.73008,"p.value_classic":0.73168,"genes":"BRCA1,DAB2,LBH"} {"GO.ID":"GO:0019725","Term":"cellular homeostasis","Annotated":634,"Significant":49,"Expected":38.29,"Rank in p.value_classic":1077,"p.value_elim":0.73262,"p.value_classic":0.04415,"genes":"AIM2,ANK2,ANKH,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,DGAT2,EDN1,ERC2,F2RL3,GHRL,HLA-DRB1,ICAM1,KCNJ2,LRP5,LRRK2,LYN,MT2A,NCF1,OCA2,P2RX7,PML,RAB20,SCO2,SIDT2,SLAMF8,SLC11A1,SLC12A3,SLC31A2,SLC4A7,SNX10,SRI,STEAP4,SV2B,TGM2,TRDN,TYRO3"} {"GO.ID":"GO:0098739","Term":"import across plasma membrane","Annotated":138,"Significant":7,"Expected":8.33,"Rank in p.value_classic":3850,"p.value_elim":0.73285,"p.value_classic":0.73527,"genes":"ACSL1,ATP1B2,KCNJ10,KCNJ15,KCNJ2,SLC12A3,SLC2A5"} {"GO.ID":"GO:0042060","Term":"wound healing","Annotated":343,"Significant":24,"Expected":20.72,"Rank in p.value_classic":2077,"p.value_elim":0.73321,"p.value_classic":0.25513,"genes":"CASP7,CD40,CEACAM1,CHMP4C,COMP,DTNBP1,EDN1,ENPP4,F2RL3,FGL1,HBEGF,ITGB5,JAK2,LYN,MERTK,MYOF,PLEK,PLSCR1,S100A10,SERPING1,SLC11A1,THBD,TSPAN32,TYRO3"} {"GO.ID":"GO:0043254","Term":"regulation of protein-containing complex assembly","Annotated":372,"Significant":20,"Expected":22.47,"Rank in p.value_classic":3855,"p.value_elim":0.73407,"p.value_classic":0.73809,"genes":"BCL2L11,CDH5,FSCN1,GBP2,GBP5,HJURP,MEFV,PLEK,PRRT2,PTGER4,RALB,SCIN,SPTBN4,STMN1,STX1A,TAL1,TMSB10,TRABD2A,TRIM31,WARS1"} {"GO.ID":"GO:0030518","Term":"intracellular steroid hormone receptor signaling pathway","Annotated":101,"Significant":5,"Expected":6.1,"Rank in p.value_classic":3851,"p.value_elim":0.73555,"p.value_classic":0.7376,"genes":"BRCA1,DAB2,JAK2,LBH,PADI2"} {"GO.ID":"GO:0001938","Term":"positive regulation of endothelial cell proliferation","Annotated":82,"Significant":4,"Expected":4.95,"Rank in p.value_classic":3852,"p.value_elim":0.73595,"p.value_classic":0.73778,"genes":"GHRL,MIR503,NRP1,VEGFC"} {"GO.ID":"GO:0071901","Term":"negative regulation of protein serine/threonine kinase activity","Annotated":82,"Significant":4,"Expected":4.95,"Rank in p.value_classic":3853,"p.value_elim":0.73595,"p.value_classic":0.73778,"genes":"AGT,LRP5,LYN,PKIB"} {"GO.ID":"GO:0006900","Term":"vesicle budding from membrane","Annotated":82,"Significant":4,"Expected":4.95,"Rank in p.value_classic":3854,"p.value_elim":0.73595,"p.value_classic":0.73778,"genes":"CHMP4C,DNM1,P2RX7,S100A10"} {"GO.ID":"GO:1902905","Term":"positive regulation of supramolecular fiber organization","Annotated":157,"Significant":8,"Expected":9.48,"Rank in p.value_classic":3856,"p.value_elim":0.73653,"p.value_classic":0.73909,"genes":"EDN1,MTSS1,NRP1,PLEK,PPM1E,PXN,S100A10,SCIN"} {"GO.ID":"GO:0032890","Term":"regulation of organic acid transport","Annotated":54,"Significant":6,"Expected":3.26,"Rank in p.value_classic":1423,"p.value_elim":0.73863,"p.value_classic":0.10563,"genes":"ACSL1,DTNBP1,EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0030010","Term":"establishment of cell polarity","Annotated":139,"Significant":7,"Expected":8.39,"Rank in p.value_classic":3860,"p.value_elim":0.73966,"p.value_classic":0.74205,"genes":"AMOT,CDH5,DYNLT1,FSCN1,MAD2L1,NDC80,WEE1"} {"GO.ID":"GO:0006813","Term":"potassium ion transport","Annotated":139,"Significant":7,"Expected":8.39,"Rank in p.value_classic":3861,"p.value_elim":0.73966,"p.value_classic":0.74205,"genes":"ANK2,ATP1B2,KCNE5,KCNJ10,KCNJ15,KCNJ2,SLC12A3"} {"GO.ID":"GO:0002088","Term":"lens development in camera-type eye","Annotated":63,"Significant":3,"Expected":3.8,"Rank in p.value_classic":3857,"p.value_elim":0.74003,"p.value_classic":0.74162,"genes":"CTNS,MAF,PLAAT3"} {"GO.ID":"GO:1902373","Term":"negative regulation of mRNA catabolic process","Annotated":63,"Significant":3,"Expected":3.8,"Rank in p.value_classic":3858,"p.value_elim":0.74003,"p.value_classic":0.74162,"genes":"DAZL,E2F1,SLC11A1"} {"GO.ID":"GO:0048844","Term":"artery morphogenesis","Annotated":63,"Significant":3,"Expected":3.8,"Rank in p.value_classic":3859,"p.value_elim":0.74003,"p.value_classic":0.74162,"genes":"COMP,EDN1,NRP1"} {"GO.ID":"GO:0046637","Term":"regulation of alpha-beta T cell differentiation","Annotated":64,"Significant":14,"Expected":3.87,"Rank in p.value_classic":313,"p.value_elim":0.74058,"p.value_classic":0.00002,"genes":"ASCL2,BCL6,CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,IL27,IRF4,JAK3,RIPK2,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:0170035","Term":"L-amino acid catabolic process","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3862,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"GLUL,IL4I1"} {"GO.ID":"GO:0090148","Term":"membrane fission","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3863,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"CHMP4C,DNM1"} {"GO.ID":"GO:0090224","Term":"regulation of spindle organization","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3864,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"CHMP4C,PARP3"} {"GO.ID":"GO:0070849","Term":"response to epidermal growth factor","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3865,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"DAB2,GAREM1"} {"GO.ID":"GO:0045022","Term":"early endosome to late endosome transport","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3866,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"DAB2,LMTK2"} {"GO.ID":"GO:0051489","Term":"regulation of filopodium assembly","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3867,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"FSCN1,NRP1"} {"GO.ID":"GO:0001881","Term":"receptor recycling","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3868,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"LMTK2,OPTN"} {"GO.ID":"GO:1903747","Term":"regulation of establishment of protein localization to mitochondrion","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3869,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0045103","Term":"intermediate filament-based process","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3870,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"INA,SYNC"} {"GO.ID":"GO:0098534","Term":"centriole assembly","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3871,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"BRCA1,WDR62"} {"GO.ID":"GO:0060038","Term":"cardiac muscle cell proliferation","Annotated":43,"Significant":2,"Expected":2.6,"Rank in p.value_classic":3872,"p.value_elim":0.74081,"p.value_classic":0.74211,"genes":"CDK1,PIM1"} {"GO.ID":"GO:0007264","Term":"small GTPase-mediated signal transduction","Annotated":462,"Significant":25,"Expected":27.9,"Rank in p.value_classic":3873,"p.value_elim":0.7415,"p.value_classic":0.74594,"genes":"AMOT,BCL6,CCNA2,CELSR1,CSF1,DAB1,F2RL3,FAM13A,FGD5,IQGAP3,ITSN1,KITLG,LRRK2,MCF2L,MRAS,NRP1,NUCB1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RHEBL1,STMN1,TAGAP,TGM2"} {"GO.ID":"GO:0097581","Term":"lamellipodium organization","Annotated":83,"Significant":4,"Expected":5.01,"Rank in p.value_classic":3906,"p.value_elim":0.74458,"p.value_classic":0.74639,"genes":"ABLIM3,ENPP2,FSCN1,S1PR1"} {"GO.ID":"GO:0001919","Term":"regulation of receptor recycling","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3874,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"OPTN"} {"GO.ID":"GO:0045684","Term":"positive regulation of epidermis development","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3875,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PLAAT4"} {"GO.ID":"GO:0099174","Term":"regulation of presynapse organization","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3876,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"MDGA1"} {"GO.ID":"GO:0003094","Term":"glomerular filtration","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3877,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"EDN1"} {"GO.ID":"GO:0060292","Term":"long-term synaptic depression","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3878,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"CD38"} {"GO.ID":"GO:0045947","Term":"negative regulation of translational initiation","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3879,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"BANK1"} {"GO.ID":"GO:0140112","Term":"extracellular vesicle biogenesis","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3880,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"ATP13A2"} {"GO.ID":"GO:0072010","Term":"glomerular epithelium development","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3881,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"EDN1"} {"GO.ID":"GO:0099560","Term":"synaptic membrane adhesion","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3882,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"MDGA1"} {"GO.ID":"GO:0062009","Term":"secondary palate development","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3883,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"MMP25"} {"GO.ID":"GO:1905606","Term":"regulation of presynapse assembly","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3884,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"MDGA1"} {"GO.ID":"GO:0010614","Term":"negative regulation of cardiac muscle hypertrophy","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3885,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"P2RX4"} {"GO.ID":"GO:0070861","Term":"regulation of protein exit from endoplasmic reticulum","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3886,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"DERL3"} {"GO.ID":"GO:0150105","Term":"protein localization to cell-cell junction","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3887,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"CDH5"} {"GO.ID":"GO:0043153","Term":"entrainment of circadian clock by photoperiod","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3888,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PML"} {"GO.ID":"GO:0140861","Term":"DNA repair-dependent chromatin remodeling","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3889,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"DTX3L"} {"GO.ID":"GO:0061339","Term":"establishment or maintenance of monopolar cell polarity","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3890,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"FSCN1"} {"GO.ID":"GO:2000114","Term":"regulation of establishment of cell polarity","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3891,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"CDH5"} {"GO.ID":"GO:2000272","Term":"negative regulation of signaling receptor activity","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3892,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"CRHBP"} {"GO.ID":"GO:0018230","Term":"peptidyl-L-cysteine S-palmitoylation","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3893,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"ZDHHC19"} {"GO.ID":"GO:0018231","Term":"peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3894,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"ZDHHC19"} {"GO.ID":"GO:0035493","Term":"SNARE complex assembly","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3895,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PRRT2"} {"GO.ID":"GO:0036119","Term":"response to platelet-derived growth factor","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3896,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"CCNA2"} {"GO.ID":"GO:0042659","Term":"regulation of cell fate specification","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3897,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"SOX17"} {"GO.ID":"GO:0001835","Term":"blastocyst hatching","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3898,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PLPP4"} {"GO.ID":"GO:0061744","Term":"motor behavior","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3899,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"ATP1B2"} {"GO.ID":"GO:0035188","Term":"hatching","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3900,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PLPP4"} {"GO.ID":"GO:0035268","Term":"protein mannosylation","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3901,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"TMTC1"} {"GO.ID":"GO:0015813","Term":"L-glutamate transmembrane transport","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3902,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"KCNJ10"} {"GO.ID":"GO:0046599","Term":"regulation of centriole replication","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3903,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"BRCA1"} {"GO.ID":"GO:0071684","Term":"organism emergence from protective structure","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3904,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"PLPP4"} {"GO.ID":"GO:0046697","Term":"decidualization","Annotated":22,"Significant":1,"Expected":1.33,"Rank in p.value_classic":3905,"p.value_elim":0.7454,"p.value_classic":0.74631,"genes":"GHRL"} {"GO.ID":"GO:0006259","Term":"DNA metabolic process","Annotated":937,"Significant":76,"Expected":56.59,"Rank in p.value_classic":656,"p.value_elim":0.74621,"p.value_classic":0.00474,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,AURKB,BACH1,BAZ1A,BCL6,BRCA1,CCNA2,CCNE2,CD28,CDC25A,CDC45,CDC6,CDCA5,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CLSPN,DMC1,DSCC1,DTL,DTX3L,E2F8,EEPD1,EME1,ESCO2,EXO1,FAM111B,FANCE,FBXO6,FEN1,GCH1,GINS1,GINS2,HELLS,HGF,HORMAD1,ISG20,JADE2,KLF4,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,NEIL3,NPM2,ORC1,PARP10,PARP3,PARP9,PCLAF,PKIB,PML,POLB,POLE2,RAD54B,RAD54L,RECQL4,RMI2,TBX21,TICRR,TK1,TONSL,TOP2A,TYMS,UBE2T,UHRF1,UNG,WEE1,XRCC2,XRN1"} {"GO.ID":"GO:0031334","Term":"positive regulation of protein-containing complex assembly","Annotated":177,"Significant":9,"Expected":10.69,"Rank in p.value_classic":3907,"p.value_elim":0.74649,"p.value_classic":0.74915,"genes":"BCL2L11,CDH5,FSCN1,GBP2,GBP5,PLEK,TAL1,TRABD2A,WARS1"} {"GO.ID":"GO:0015914","Term":"phospholipid transport","Annotated":82,"Significant":8,"Expected":4.95,"Rank in p.value_classic":1511,"p.value_elim":0.74661,"p.value_classic":0.12117,"genes":"ABCB1,ANO4,ATP8B1,P2RX7,PLSCR1,PLSCR4,TNFAIP8L3,XKR6"} {"GO.ID":"GO:0044255","Term":"cellular lipid metabolic process","Annotated":778,"Significant":43,"Expected":46.99,"Rank in p.value_classic":3927,"p.value_elim":0.74789,"p.value_classic":0.75365,"genes":"ACOT4,ACSL1,APPL2,BRCA1,C3,CD74,CDS1,CEACAM1,CISH,CYP1A1,DGAT2,DHRS3,DHRS9,EDN1,ENPP2,EPHX1,G6PC1,GAL3ST4,GGT5,GK,LCLAT1,LPL,LTC4S,NAAA,NR4A3,P2RX7,PCYT1A,PDK4,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PNPLA3,RNF213,SERINC5,SGPL1,SLC45A3,SOCS1,TMEM150A,TNFAIP8L3"} {"GO.ID":"GO:0048608","Term":"reproductive structure development","Annotated":232,"Significant":12,"Expected":14.01,"Rank in p.value_classic":3909,"p.value_elim":0.74806,"p.value_classic":0.75112,"genes":"BCL2L11,C3,DMC1,HESX1,KITLG,MERTK,RHOBTB3,SGPL1,TIFAB,TNFAIP6,TNFSF10,TYRO3"} {"GO.ID":"GO:0051640","Term":"organelle localization","Annotated":552,"Significant":30,"Expected":33.34,"Rank in p.value_classic":3928,"p.value_elim":0.74954,"p.value_classic":0.75433,"genes":"ATP13A2,AURKB,BIRC5,CADPS2,CDCA5,CDT1,CENPF,CHMP4C,DAB1,DNM1,DTNBP1,DYNLT1,EML4,LIMK2,LRRK2,LYN,MAD2L1,NDC80,NR4A3,NUF2,NUSAP1,PLEK,RALB,S100A13,SPC24,SPC25,STX11,STX1A,SYT1,ZWINT"} {"GO.ID":"GO:0043489","Term":"RNA stabilization","Annotated":64,"Significant":3,"Expected":3.87,"Rank in p.value_classic":3910,"p.value_elim":0.74969,"p.value_classic":0.75125,"genes":"DAZL,E2F1,SLC11A1"} {"GO.ID":"GO:0009799","Term":"specification of symmetry","Annotated":103,"Significant":5,"Expected":6.22,"Rank in p.value_classic":3911,"p.value_elim":0.75105,"p.value_classic":0.75304,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0009855","Term":"determination of bilateral symmetry","Annotated":103,"Significant":5,"Expected":6.22,"Rank in p.value_classic":3912,"p.value_elim":0.75105,"p.value_classic":0.75304,"genes":"ASB2,DLL1,DNAAF1,MICAL2,SOX17"} {"GO.ID":"GO:0030509","Term":"BMP signaling pathway","Annotated":122,"Significant":6,"Expected":7.37,"Rank in p.value_classic":3913,"p.value_elim":0.75133,"p.value_classic":0.75351,"genes":"CDH5,CHRD,COMP,FSTL4,HTRA1,TNFAIP6"} {"GO.ID":"GO:0014037","Term":"Schwann cell differentiation","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3914,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"CDK1,EGR2"} {"GO.ID":"GO:0051926","Term":"negative regulation of calcium ion transport","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3915,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"SRI,TRDN"} {"GO.ID":"GO:0043039","Term":"tRNA aminoacylation","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3916,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"KARS1,WARS1"} {"GO.ID":"GO:0032330","Term":"regulation of chondrocyte differentiation","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3917,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"MAF,SCIN"} {"GO.ID":"GO:0050881","Term":"musculoskeletal movement","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3918,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"COMP,KCNJ2"} {"GO.ID":"GO:0031146","Term":"SCF-dependent proteasomal ubiquitin-dependent protein catabolic process","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3919,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"CCNF,FBXO6"} {"GO.ID":"GO:0042789","Term":"mRNA transcription by RNA polymerase II","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3920,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"EPAS1,S100A10"} {"GO.ID":"GO:0085029","Term":"extracellular matrix assembly","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3921,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"AGT,ANTXR1"} {"GO.ID":"GO:0050994","Term":"regulation of lipid catabolic process","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3922,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"HCAR2,PDE3B"} {"GO.ID":"GO:0032527","Term":"protein exit from endoplasmic reticulum","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3923,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"DERL3,MAP1LC3C"} {"GO.ID":"GO:0048538","Term":"thymus development","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3924,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"BCL2L11,EPHB3"} {"GO.ID":"GO:0060071","Term":"Wnt signaling pathway, planar cell polarity pathway","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3925,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"CELSR1,DAB2"} {"GO.ID":"GO:0007608","Term":"sensory perception of smell","Annotated":44,"Significant":2,"Expected":2.66,"Rank in p.value_classic":3926,"p.value_elim":0.7523,"p.value_classic":0.75358,"genes":"B2M,OR2I1P"} {"GO.ID":"GO:0060538","Term":"skeletal muscle organ development","Annotated":141,"Significant":7,"Expected":8.52,"Rank in p.value_classic":3931,"p.value_elim":0.75291,"p.value_classic":0.75524,"genes":"ASB2,ATF3,DLL1,EGR2,MAFF,MYOZ2,VAMP5"} {"GO.ID":"GO:0072524","Term":"pyridine-containing compound metabolic process","Annotated":141,"Significant":7,"Expected":8.52,"Rank in p.value_classic":3932,"p.value_elim":0.75291,"p.value_classic":0.75524,"genes":"CD38,IDO1,IDO2,P2RX7,PARP10,PARP9,SLC2A6"} {"GO.ID":"GO:0009063","Term":"amino acid catabolic process","Annotated":84,"Significant":4,"Expected":5.07,"Rank in p.value_classic":3930,"p.value_elim":0.75299,"p.value_classic":0.75478,"genes":"GLUL,IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0048762","Term":"mesenchymal cell differentiation","Annotated":215,"Significant":11,"Expected":12.99,"Rank in p.value_classic":3933,"p.value_elim":0.75428,"p.value_classic":0.75717,"genes":"ADAM8,AGT,AMER1,DAB2,EDN1,GLIPR2,HGF,KITLG,NRP1,SEMA6B,STAT1"} {"GO.ID":"GO:0045596","Term":"negative regulation of cell differentiation","Annotated":528,"Significant":37,"Expected":31.89,"Rank in p.value_classic":1852,"p.value_elim":0.75632,"p.value_classic":0.193,"genes":"APPL2,ASCL2,B2M,BCL6,BHLHE41,CD74,CEACAM1,CHRD,CTLA4,CXCL10,DAB1,DLL1,DYNLT1,E2F1,FGL2,FSTL4,HLA-G,IRF1,JAK3,LAG3,LBH,LILRB3,LRP5,LYN,MMP9,NRP1,RAPGEF2,SEMA6B,SOCS1,STAT1,TBX21,TMEM119,TMEM176A,TMEM176B,TNFAIP6,VEGFC,ZC3H12A"} {"GO.ID":"GO:0043009","Term":"chordate embryonic development","Annotated":554,"Significant":30,"Expected":33.46,"Rank in p.value_classic":3942,"p.value_elim":0.75636,"p.value_classic":0.76107,"genes":"AMOT,ASCL2,BCL2L11,BRCA1,CELSR1,CENPU,CHRD,DLL1,E2F8,EDN1,EPAS1,GINS1,HORMAD1,IFT122,KLF4,MAFF,NCAPG2,NPM2,PCDH12,PLCD3,PLPP4,PLXNA2,POLB,RRM2,SCO2,SH3PXD2A,SOX17,SSBP3,XRCC2,XYLT1"} {"GO.ID":"GO:0055082","Term":"intracellular chemical homeostasis","Annotated":545,"Significant":44,"Expected":32.92,"Rank in p.value_classic":974,"p.value_elim":0.7566,"p.value_classic":0.02971,"genes":"ANK2,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,DGAT2,EDN1,ERC2,F2RL3,GHRL,HLA-DRB1,ICAM1,KCNJ2,LRP5,LRRK2,LYN,MT2A,NCF1,OCA2,P2RX7,PML,RAB20,SCO2,SIDT2,SLAMF8,SLC11A1,SLC31A2,SLC4A7,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0072522","Term":"purine-containing compound biosynthetic process","Annotated":234,"Significant":12,"Expected":14.13,"Rank in p.value_classic":3943,"p.value_elim":0.7583,"p.value_classic":0.76129,"genes":"ACSL1,AK1,IDO1,IDO2,NPR1,PARP10,PARP9,PDK4,PID1,PRTFDC1,SLC4A7,VPS9D1"} {"GO.ID":"GO:0080171","Term":"lytic vacuole organization","Annotated":104,"Significant":5,"Expected":6.28,"Rank in p.value_classic":3934,"p.value_elim":0.75854,"p.value_classic":0.76051,"genes":"CHMP4C,LRRK2,OCA2,P2RX7,RAB20"} {"GO.ID":"GO:0007040","Term":"lysosome organization","Annotated":104,"Significant":5,"Expected":6.28,"Rank in p.value_classic":3935,"p.value_elim":0.75854,"p.value_classic":0.76051,"genes":"CHMP4C,LRRK2,OCA2,P2RX7,RAB20"} {"GO.ID":"GO:0070646","Term":"protein modification by small protein removal","Annotated":104,"Significant":5,"Expected":6.28,"Rank in p.value_classic":3936,"p.value_elim":0.75854,"p.value_classic":0.76051,"genes":"CYLD,OTUD1,STAMBPL1,TANK,ZC3H12A"} {"GO.ID":"GO:0002686","Term":"negative regulation of leukocyte migration","Annotated":41,"Significant":6,"Expected":2.48,"Rank in p.value_classic":1030,"p.value_elim":0.75901,"p.value_classic":0.03514,"genes":"KLRK1,PADI2,PTGER4,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0032007","Term":"negative regulation of TOR signaling","Annotated":65,"Significant":3,"Expected":3.93,"Rank in p.value_classic":3937,"p.value_elim":0.75906,"p.value_classic":0.7606,"genes":"CASTOR1,DEPTOR,SESN3"} {"GO.ID":"GO:0150116","Term":"regulation of cell-substrate junction organization","Annotated":65,"Significant":3,"Expected":3.93,"Rank in p.value_classic":3938,"p.value_elim":0.75906,"p.value_classic":0.7606,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:1902017","Term":"regulation of cilium assembly","Annotated":65,"Significant":3,"Expected":3.93,"Rank in p.value_classic":3939,"p.value_elim":0.75906,"p.value_classic":0.7606,"genes":"CDKL1,CYLD,LIMK2"} {"GO.ID":"GO:0030032","Term":"lamellipodium assembly","Annotated":65,"Significant":3,"Expected":3.93,"Rank in p.value_classic":3940,"p.value_elim":0.75906,"p.value_classic":0.7606,"genes":"ABLIM3,FSCN1,S1PR1"} {"GO.ID":"GO:0046889","Term":"positive regulation of lipid biosynthetic process","Annotated":65,"Significant":3,"Expected":3.93,"Rank in p.value_classic":3941,"p.value_elim":0.75906,"p.value_classic":0.7606,"genes":"CD74,DAB2,SLC45A3"} {"GO.ID":"GO:0044090","Term":"positive regulation of vacuole organization","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3944,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"RALB"} {"GO.ID":"GO:0051968","Term":"positive regulation of synaptic transmission, glutamatergic","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3945,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"DTNBP1"} {"GO.ID":"GO:0046949","Term":"fatty-acyl-CoA biosynthetic process","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3946,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"ACSL1"} {"GO.ID":"GO:2000042","Term":"negative regulation of double-strand break repair via homologous recombination","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3947,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"RMI2"} {"GO.ID":"GO:0120261","Term":"regulation of heterochromatin organization","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3948,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"BAZ1A"} {"GO.ID":"GO:0048011","Term":"neurotrophin TRK receptor signaling pathway","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3949,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"AGT"} {"GO.ID":"GO:0051016","Term":"barbed-end actin filament capping","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3950,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"SCIN"} {"GO.ID":"GO:0003338","Term":"metanephros morphogenesis","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3951,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"STAT1"} {"GO.ID":"GO:0009648","Term":"photoperiodism","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3952,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"PML"} {"GO.ID":"GO:0070841","Term":"inclusion body assembly","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3953,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"UBD"} {"GO.ID":"GO:0007039","Term":"protein catabolic process in the vacuole","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3954,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"ATP13A2"} {"GO.ID":"GO:0014741","Term":"negative regulation of muscle hypertrophy","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3955,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"P2RX4"} {"GO.ID":"GO:2000463","Term":"positive regulation of excitatory postsynaptic potential","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3956,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"STX1A"} {"GO.ID":"GO:0031445","Term":"regulation of heterochromatin formation","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3957,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"BAZ1A"} {"GO.ID":"GO:0097150","Term":"neuronal stem cell population maintenance","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3958,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"DLL1"} {"GO.ID":"GO:0007263","Term":"nitric oxide mediated signal transduction","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3959,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"AGT"} {"GO.ID":"GO:0014912","Term":"negative regulation of smooth muscle cell migration","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3960,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"MIR503"} {"GO.ID":"GO:0021680","Term":"cerebellar Purkinje cell layer development","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3961,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"DLL1"} {"GO.ID":"GO:0045109","Term":"intermediate filament organization","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3962,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"INA"} {"GO.ID":"GO:0031646","Term":"positive regulation of nervous system process","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3963,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"EGR2"} {"GO.ID":"GO:0046755","Term":"viral budding","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3964,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"CHMP4C"} {"GO.ID":"GO:0071549","Term":"cellular response to dexamethasone stimulus","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3965,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"JAK2"} {"GO.ID":"GO:0097502","Term":"mannosylation","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3966,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"TMTC1"} {"GO.ID":"GO:0006541","Term":"glutamine metabolic process","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3967,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"GLUL"} {"GO.ID":"GO:0006536","Term":"glutamate metabolic process","Annotated":23,"Significant":1,"Expected":1.39,"Rank in p.value_classic":3968,"p.value_elim":0.76077,"p.value_classic":0.76166,"genes":"GLUL"} {"GO.ID":"GO:1901657","Term":"glycosyl compound metabolic process","Annotated":64,"Significant":7,"Expected":3.87,"Rank in p.value_classic":1332,"p.value_elim":0.76091,"p.value_classic":0.09011,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ENPP4,PRTFDC1,TK1,TYMP"} {"GO.ID":"GO:0009408","Term":"response to heat","Annotated":85,"Significant":4,"Expected":5.13,"Rank in p.value_classic":3969,"p.value_elim":0.76119,"p.value_classic":0.76295,"genes":"CXCL10,HSBP1L1,LYN,TFEC"} {"GO.ID":"GO:0030301","Term":"cholesterol transport","Annotated":85,"Significant":4,"Expected":5.13,"Rank in p.value_classic":3970,"p.value_elim":0.76119,"p.value_classic":0.76295,"genes":"EEPD1,OSBPL6,SOAT1,TTC39B"} {"GO.ID":"GO:0030100","Term":"regulation of endocytosis","Annotated":239,"Significant":23,"Expected":14.43,"Rank in p.value_classic":849,"p.value_elim":0.76121,"p.value_classic":0.01825,"genes":"APPL2,B2M,C2,C3,C4A,C4B,CD300LF,DAB2,DLL1,DTNBP1,DYSF,FCN1,IL15,IL15RA,LRRK2,MERTK,NECAB2,NOD2,PLSCR1,SLC11A1,STAP1,SYNE1,TGM2"} {"GO.ID":"GO:0043010","Term":"camera-type eye development","Annotated":253,"Significant":13,"Expected":15.28,"Rank in p.value_classic":3978,"p.value_elim":0.76234,"p.value_classic":0.76543,"genes":"CTNS,CYP1A1,DLL1,DTNBP1,HESX1,IFT122,KLF4,LIMK2,LRP5,MAF,MERTK,NRP1,PLAAT3"} {"GO.ID":"GO:0031400","Term":"negative regulation of protein modification process","Annotated":379,"Significant":20,"Expected":22.89,"Rank in p.value_classic":3980,"p.value_elim":0.76294,"p.value_classic":0.76674,"genes":"AGT,CEACAM1,DEPTOR,DTNBP1,DTX3L,HGF,LRP5,LRRK2,LYN,MAD2L1,MVP,NLRP12,PARP10,PARP14,PID1,PKIB,PPM1E,SOCS1,WARS1,ZC3H12A"} {"GO.ID":"GO:0061458","Term":"reproductive system development","Annotated":235,"Significant":12,"Expected":14.19,"Rank in p.value_classic":3979,"p.value_elim":0.76331,"p.value_classic":0.76627,"genes":"BCL2L11,C3,DMC1,HESX1,KITLG,MERTK,RHOBTB3,SGPL1,TIFAB,TNFAIP6,TNFSF10,TYRO3"} {"GO.ID":"GO:0043038","Term":"amino acid activation","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3971,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"KARS1,WARS1"} {"GO.ID":"GO:0070169","Term":"positive regulation of biomineral tissue development","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3972,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"P2RX7,TMEM119"} {"GO.ID":"GO:0050879","Term":"multicellular organismal movement","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3973,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"COMP,KCNJ2"} {"GO.ID":"GO:0046324","Term":"regulation of glucose import","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3974,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"APPL2,PID1"} {"GO.ID":"GO:2000785","Term":"regulation of autophagosome assembly","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3975,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"LRRK2,RALB"} {"GO.ID":"GO:0006778","Term":"porphyrin-containing compound metabolic process","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3976,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"ALAS1,CYP1A1"} {"GO.ID":"GO:0007566","Term":"embryo implantation","Annotated":45,"Significant":2,"Expected":2.72,"Rank in p.value_classic":3977,"p.value_elim":0.76335,"p.value_classic":0.7646,"genes":"ACOD1,MMP9"} {"GO.ID":"GO:0072073","Term":"kidney epithelium development","Annotated":124,"Significant":6,"Expected":7.49,"Rank in p.value_classic":3981,"p.value_elim":0.76502,"p.value_classic":0.76714,"genes":"AGT,CTNS,DLL1,EDN1,MTSS1,STAT1"} {"GO.ID":"GO:0051346","Term":"negative regulation of hydrolase activity","Annotated":143,"Significant":7,"Expected":8.64,"Rank in p.value_classic":3984,"p.value_elim":0.76566,"p.value_classic":0.76794,"genes":"CARD16,KLF4,KLRK1,LAMP3,LRRK2,MMP9,SERPING1"} {"GO.ID":"GO:0006939","Term":"smooth muscle contraction","Annotated":79,"Significant":7,"Expected":4.77,"Rank in p.value_classic":1862,"p.value_elim":0.76569,"p.value_classic":0.19921,"genes":"CD38,COMP,EDN1,GHRL,PROK2,SSTR2,TIFAB"} {"GO.ID":"GO:1904950","Term":"negative regulation of establishment of protein localization","Annotated":105,"Significant":5,"Expected":6.34,"Rank in p.value_classic":3982,"p.value_elim":0.76586,"p.value_classic":0.7678,"genes":"DERL3,GHRL,IL12A,LRRK2,RSAD2"} {"GO.ID":"GO:0032204","Term":"regulation of telomere maintenance","Annotated":105,"Significant":5,"Expected":6.34,"Rank in p.value_classic":3983,"p.value_elim":0.76586,"p.value_classic":0.7678,"genes":"AURKB,GCH1,PKIB,PML,XRN1"} {"GO.ID":"GO:0050808","Term":"synapse organization","Annotated":398,"Significant":21,"Expected":24.04,"Rank in p.value_classic":3987,"p.value_elim":0.7675,"p.value_classic":0.77136,"genes":"C1QB,C3,CBLN3,COLQ,CTTNBP2,CX3CR1,DLGAP3,DTNBP1,EPHB3,ERC2,GABRA3,GHRL,INA,LGI2,LRRK2,MDGA1,NRCAM,NRP1,PCDHGC3,SPTBN4,THBS2"} {"GO.ID":"GO:0061053","Term":"somite development","Annotated":66,"Significant":3,"Expected":3.99,"Rank in p.value_classic":3985,"p.value_elim":0.76815,"p.value_classic":0.76966,"genes":"DLL1,PLXNA2,XRCC2"} {"GO.ID":"GO:0043112","Term":"receptor metabolic process","Annotated":66,"Significant":3,"Expected":3.99,"Rank in p.value_classic":3986,"p.value_elim":0.76815,"p.value_classic":0.76966,"genes":"DTX3L,LMTK2,OPTN"} {"GO.ID":"GO:0044087","Term":"regulation of cellular component biogenesis","Annotated":856,"Significant":47,"Expected":51.7,"Rank in p.value_classic":4015,"p.value_elim":0.77181,"p.value_classic":0.77754,"genes":"AGT,ANLN,ANTXR1,ATP13A2,ATP8B1,BCL2L11,BRCA1,CDH5,CDKL1,CHMP4C,COLQ,CYLD,EPHB3,FAM107A,FSCN1,GBP2,GBP5,GHRL,HJURP,ICAM1,LIMK2,LRRK2,MDGA1,MEFV,MTSS1,NRP1,P2RX7,PLEK,PPM1E,PRRT2,PTGER4,PXN,RALB,RAPGEF2,S100A10,S1PR1,SCIN,SPTBN4,STAP1,STMN1,STX1A,TAL1,THBS2,TMSB10,TRABD2A,TRIM31,WARS1"} {"GO.ID":"GO:0003012","Term":"muscle system process","Annotated":321,"Significant":23,"Expected":19.39,"Rank in p.value_classic":1943,"p.value_elim":0.77308,"p.value_classic":0.22547,"genes":"AGT,ANK2,CAMK2D,CD38,COMP,EDN1,GHRL,KCNE5,KCNJ2,MYOF,MYOZ2,NR4A3,P2RX4,PDE4B,PROK2,SCN4B,SCO2,SRI,SSPN,SSTR2,TIFAB,TRDN,ZC3H12A"} {"GO.ID":"GO:0071715","Term":"icosanoid transport","Annotated":35,"Significant":5,"Expected":2.11,"Rank in p.value_classic":1159,"p.value_elim":0.77373,"p.value_classic":0.05734,"genes":"ABCC11,EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0060135","Term":"maternal process involved in female pregnancy","Annotated":46,"Significant":2,"Expected":2.78,"Rank in p.value_classic":3988,"p.value_elim":0.77397,"p.value_classic":0.7752,"genes":"APOL2,GHRL"} {"GO.ID":"GO:1904036","Term":"negative regulation of epithelial cell apoptotic process","Annotated":46,"Significant":2,"Expected":2.78,"Rank in p.value_classic":3989,"p.value_elim":0.77397,"p.value_classic":0.7752,"genes":"CDH5,ICAM1"} {"GO.ID":"GO:0051055","Term":"negative regulation of lipid biosynthetic process","Annotated":46,"Significant":2,"Expected":2.78,"Rank in p.value_classic":3990,"p.value_elim":0.77397,"p.value_classic":0.7752,"genes":"BRCA1,CEACAM1"} {"GO.ID":"GO:0045778","Term":"positive regulation of ossification","Annotated":46,"Significant":2,"Expected":2.78,"Rank in p.value_classic":3991,"p.value_elim":0.77397,"p.value_classic":0.7752,"genes":"P2RX7,TMEM119"} {"GO.ID":"GO:0060042","Term":"retina morphogenesis in camera-type eye","Annotated":46,"Significant":2,"Expected":2.78,"Rank in p.value_classic":3992,"p.value_elim":0.77397,"p.value_classic":0.7752,"genes":"DLL1,LRP5"} {"GO.ID":"GO:0150063","Term":"visual system development","Annotated":292,"Significant":15,"Expected":17.64,"Rank in p.value_classic":4016,"p.value_elim":0.77478,"p.value_classic":0.778,"genes":"C3,CTNS,CYP1A1,DLL1,DTNBP1,HESX1,IFT122,KLF4,LIMK2,LRP5,MAF,MERTK,NRP1,PLAAT3,SCO2"} {"GO.ID":"GO:0030262","Term":"apoptotic nuclear changes","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3993,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"TOP2A"} {"GO.ID":"GO:0060487","Term":"lung epithelial cell differentiation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3994,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"AGR2"} {"GO.ID":"GO:0060479","Term":"lung cell differentiation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3995,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"AGR2"} {"GO.ID":"GO:0022030","Term":"telencephalon glial cell migration","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3996,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"DAB1"} {"GO.ID":"GO:0042059","Term":"negative regulation of epidermal growth factor receptor signaling pathway","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3997,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"MVP"} {"GO.ID":"GO:0042026","Term":"protein refolding","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3998,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"B2M"} {"GO.ID":"GO:0010800","Term":"positive regulation of peptidyl-threonine phosphorylation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":3999,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"RIPK2"} {"GO.ID":"GO:0099590","Term":"neurotransmitter receptor internalization","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4000,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"SYNE1"} {"GO.ID":"GO:0060765","Term":"regulation of androgen receptor signaling pathway","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4001,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"DAB2"} {"GO.ID":"GO:0003416","Term":"endochondral bone growth","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4002,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"COMP"} {"GO.ID":"GO:0035020","Term":"regulation of Rac protein signal transduction","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4003,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"RASGRF1"} {"GO.ID":"GO:0061384","Term":"heart trabecula morphogenesis","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4004,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"S1PR1"} {"GO.ID":"GO:0010922","Term":"positive regulation of phosphatase activity","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4005,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"PLEK"} {"GO.ID":"GO:1903421","Term":"regulation of synaptic vesicle recycling","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4006,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"LRRK2"} {"GO.ID":"GO:0018279","Term":"protein N-linked glycosylation via asparagine","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4007,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"DERL3"} {"GO.ID":"GO:2000737","Term":"negative regulation of stem cell differentiation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4008,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"LBH"} {"GO.ID":"GO:0021801","Term":"cerebral cortex radial glia-guided migration","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4009,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"DAB1"} {"GO.ID":"GO:0048710","Term":"regulation of astrocyte differentiation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4010,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"DAB1"} {"GO.ID":"GO:0048730","Term":"epidermis morphogenesis","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4011,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"KLF4"} {"GO.ID":"GO:0021544","Term":"subpallium development","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4012,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"LRRK2"} {"GO.ID":"GO:0015701","Term":"bicarbonate transport","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4013,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"SLC4A7"} {"GO.ID":"GO:0031954","Term":"positive regulation of protein autophosphorylation","Annotated":24,"Significant":1,"Expected":1.45,"Rank in p.value_classic":4014,"p.value_elim":0.7752,"p.value_classic":0.77608,"genes":"VEGFC"} {"GO.ID":"GO:0034728","Term":"nucleosome organization","Annotated":87,"Significant":4,"Expected":5.25,"Rank in p.value_classic":4021,"p.value_elim":0.77695,"p.value_classic":0.77865,"genes":"BAZ1A,CHAF1B,H2BC21,MCM2"} {"GO.ID":"GO:0006493","Term":"protein O-linked glycosylation","Annotated":87,"Significant":4,"Expected":5.25,"Rank in p.value_classic":4022,"p.value_elim":0.77695,"p.value_classic":0.77865,"genes":"GALNT18,GCNT3,IL15,TMTC1"} {"GO.ID":"GO:0060395","Term":"SMAD protein signal transduction","Annotated":67,"Significant":3,"Expected":4.05,"Rank in p.value_classic":4017,"p.value_elim":0.77695,"p.value_classic":0.77844,"genes":"DAB2,JAK2,PML"} {"GO.ID":"GO:0072088","Term":"nephron epithelium morphogenesis","Annotated":67,"Significant":3,"Expected":4.05,"Rank in p.value_classic":4018,"p.value_elim":0.77695,"p.value_classic":0.77844,"genes":"AGT,CTNS,STAT1"} {"GO.ID":"GO:0071479","Term":"cellular response to ionizing radiation","Annotated":67,"Significant":3,"Expected":4.05,"Rank in p.value_classic":4019,"p.value_elim":0.77695,"p.value_classic":0.77844,"genes":"BRCA1,TANK,TMEM109"} {"GO.ID":"GO:0006112","Term":"energy reserve metabolic process","Annotated":67,"Significant":3,"Expected":4.05,"Rank in p.value_classic":4020,"p.value_elim":0.77695,"p.value_classic":0.77844,"genes":"G6PC1,PCDH12,PID1"} {"GO.ID":"GO:0090407","Term":"organophosphate biosynthetic process","Annotated":525,"Significant":28,"Expected":31.71,"Rank in p.value_classic":4025,"p.value_elim":0.77716,"p.value_classic":0.78151,"genes":"ACSL1,AK1,CDS1,CISH,CMPK2,GK,IDO1,IDO2,KARS1,LCLAT1,NPR1,PARP10,PARP9,PCYT1A,PDK4,PID1,PLAAT3,PLEK,PLSCR1,PNPLA3,RRM2,SERINC5,SLC4A7,SOCS1,TK1,TMEM150A,TYMS,VPS9D1"} {"GO.ID":"GO:0071456","Term":"cellular response to hypoxia","Annotated":126,"Significant":6,"Expected":7.61,"Rank in p.value_classic":4023,"p.value_elim":0.77815,"p.value_classic":0.78021,"genes":"ADAM8,CCNA2,CYSLTR1,EDN1,EPAS1,PMAIP1"} {"GO.ID":"GO:0048515","Term":"spermatid differentiation","Annotated":126,"Significant":6,"Expected":7.61,"Rank in p.value_classic":4024,"p.value_elim":0.77815,"p.value_classic":0.78021,"genes":"ADGB,DMC1,OCA2,SEPTIN4,TMEM119,ZMYND15"} {"GO.ID":"GO:0033045","Term":"regulation of sister chromatid segregation","Annotated":99,"Significant":13,"Expected":5.98,"Rank in p.value_classic":696,"p.value_elim":0.77933,"p.value_classic":0.00646,"genes":"AURKB,BIRC5,BUB1B,CDC6,CDK1,CENPF,MAD2L1,NDC80,NUF2,RMI2,SPC24,SPC25,ZWINT"} {"GO.ID":"GO:0045935","Term":"positive regulation of nucleobase-containing compound metabolic process","Annotated":1738,"Significant":98,"Expected":104.97,"Rank in p.value_classic":4039,"p.value_elim":0.78085,"p.value_classic":0.78912,"genes":"ABLIM3,AGT,ASCL2,ATF3,ATF5,AURKB,BACH1,BAZ1A,BMAL2,BRCA1,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDK1,CDT1,CHTF18,CIITA,CXCL10,DAB2,DLL1,DSCC1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,GCH1,GTPBP1,HGF,HLA-DRB1,IL31RA,IL4I1,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NOD2,NPM2,NR4A3,OLIG1,ONECUT2,OSM,P2RX7,PARP3,PARP9,PID1,PIM1,PKIB,PLSCR1,PML,PYHIN1,RELB,RIPK2,S100A10,S1PR1,SAMD4A,SBNO2,SLC11A1,SOX17,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TLR7,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WEE1,ZC3H12A,ZNF395"} {"GO.ID":"GO:1903829","Term":"positive regulation of protein localization","Annotated":420,"Significant":22,"Expected":25.37,"Rank in p.value_classic":4034,"p.value_elim":0.7829,"p.value_classic":0.78671,"genes":"ABLIM3,ADAM8,AGR2,ATP13A2,CD38,CDK1,CYLD,DTX3L,EDN1,GHRL,HCAR2,HLA-DRB1,JAK2,LIMK2,NECAB2,P2RX7,PARP9,PYHIN1,SRI,TNFAIP6,VEGFC,ZC3H12A"} {"GO.ID":"GO:0048880","Term":"sensory system development","Annotated":294,"Significant":15,"Expected":17.76,"Rank in p.value_classic":4033,"p.value_elim":0.78338,"p.value_classic":0.78654,"genes":"C3,CTNS,CYP1A1,DLL1,DTNBP1,HESX1,IFT122,KLF4,LIMK2,LRP5,MAF,MERTK,NRP1,PLAAT3,SCO2"} {"GO.ID":"GO:0071453","Term":"cellular response to oxygen levels","Annotated":146,"Significant":7,"Expected":8.82,"Rank in p.value_classic":4031,"p.value_elim":0.78389,"p.value_classic":0.78608,"genes":"ADAM8,CCNA2,CYSLTR1,EDN1,EPAS1,FAS,PMAIP1"} {"GO.ID":"GO:0072348","Term":"sulfur compound transport","Annotated":47,"Significant":2,"Expected":2.84,"Rank in p.value_classic":4026,"p.value_elim":0.78417,"p.value_classic":0.78538,"genes":"ABCG2,CTNS"} {"GO.ID":"GO:0021536","Term":"diencephalon development","Annotated":47,"Significant":2,"Expected":2.84,"Rank in p.value_classic":4027,"p.value_elim":0.78417,"p.value_classic":0.78538,"genes":"HESX1,NRP1"} {"GO.ID":"GO:0031648","Term":"protein destabilization","Annotated":47,"Significant":2,"Expected":2.84,"Rank in p.value_classic":4028,"p.value_elim":0.78417,"p.value_classic":0.78538,"genes":"PYHIN1,SOX17"} {"GO.ID":"GO:1902743","Term":"regulation of lamellipodium organization","Annotated":47,"Significant":2,"Expected":2.84,"Rank in p.value_classic":4029,"p.value_elim":0.78417,"p.value_classic":0.78538,"genes":"ENPP2,FSCN1"} {"GO.ID":"GO:0006513","Term":"protein monoubiquitination","Annotated":47,"Significant":2,"Expected":2.84,"Rank in p.value_classic":4030,"p.value_elim":0.78417,"p.value_classic":0.78538,"genes":"DTL,UBE2T"} {"GO.ID":"GO:0032355","Term":"response to estradiol","Annotated":88,"Significant":4,"Expected":5.31,"Rank in p.value_classic":4032,"p.value_elim":0.78451,"p.value_classic":0.78619,"genes":"CCNA2,CD38,CRHBP,SSTR2"} {"GO.ID":"GO:0032886","Term":"regulation of microtubule-based process","Annotated":221,"Significant":11,"Expected":13.35,"Rank in p.value_classic":4037,"p.value_elim":0.7847,"p.value_classic":0.78741,"genes":"ATF5,BRCA1,CCNF,CDH5,CHMP4C,CYLD,DNAAF1,FAM107A,PARP3,STMN1,WDR62"} {"GO.ID":"GO:0072028","Term":"nephron morphogenesis","Annotated":68,"Significant":3,"Expected":4.11,"Rank in p.value_classic":4035,"p.value_elim":0.78548,"p.value_classic":0.78694,"genes":"AGT,CTNS,STAT1"} {"GO.ID":"GO:0061333","Term":"renal tubule morphogenesis","Annotated":68,"Significant":3,"Expected":4.11,"Rank in p.value_classic":4036,"p.value_elim":0.78548,"p.value_classic":0.78694,"genes":"AGT,CTNS,MTSS1"} {"GO.ID":"GO:0021987","Term":"cerebral cortex development","Annotated":108,"Significant":5,"Expected":6.52,"Rank in p.value_classic":4038,"p.value_elim":0.78682,"p.value_classic":0.78867,"genes":"DAB1,KIF26A,MDGA1,TACC2,WDR62"} {"GO.ID":"GO:0006220","Term":"pyrimidine nucleotide metabolic process","Annotated":47,"Significant":6,"Expected":2.84,"Rank in p.value_classic":1196,"p.value_elim":0.78719,"p.value_classic":0.06213,"genes":"CMPK2,DPYS,SLC4A7,TYMP,TYMS,UNG"} {"GO.ID":"GO:0110053","Term":"regulation of actin filament organization","Annotated":240,"Significant":12,"Expected":14.49,"Rank in p.value_classic":4057,"p.value_elim":0.78729,"p.value_classic":0.7901,"genes":"MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0043304","Term":"regulation of mast cell degranulation","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4040,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"LYN"} {"GO.ID":"GO:0070723","Term":"response to cholesterol","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4041,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"GRAMD1B"} {"GO.ID":"GO:0031468","Term":"nuclear membrane reassembly","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4042,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"CHMP4C"} {"GO.ID":"GO:0006026","Term":"aminoglycan catabolic process","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4043,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"LYVE1"} {"GO.ID":"GO:0009954","Term":"proximal/distal pattern formation","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4044,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"DLL1"} {"GO.ID":"GO:0071480","Term":"cellular response to gamma radiation","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4045,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"TMEM109"} {"GO.ID":"GO:0033598","Term":"mammary gland epithelial cell proliferation","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4046,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"IQGAP3"} {"GO.ID":"GO:0051156","Term":"glucose 6-phosphate metabolic process","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4047,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"G6PC1"} {"GO.ID":"GO:0032878","Term":"regulation of establishment or maintenance of cell polarity","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4048,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"CDH5"} {"GO.ID":"GO:0032801","Term":"receptor catabolic process","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4049,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"DTX3L"} {"GO.ID":"GO:0071295","Term":"cellular response to vitamin","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4050,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"PIM1"} {"GO.ID":"GO:0033617","Term":"mitochondrial cytochrome c oxidase assembly","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4051,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"SCO2"} {"GO.ID":"GO:0032511","Term":"late endosome to vacuole transport via multivesicular body sorting pathway","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4052,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"CHMP4C"} {"GO.ID":"GO:0035115","Term":"embryonic forelimb morphogenesis","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4053,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"IFT122"} {"GO.ID":"GO:0097205","Term":"renal filtration","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4054,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"EDN1"} {"GO.ID":"GO:0051560","Term":"mitochondrial calcium ion homeostasis","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4055,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"TGM2"} {"GO.ID":"GO:0021983","Term":"pituitary gland development","Annotated":25,"Significant":1,"Expected":1.51,"Rank in p.value_classic":4056,"p.value_elim":0.78877,"p.value_classic":0.78963,"genes":"HESX1"} {"GO.ID":"GO:0021537","Term":"telencephalon development","Annotated":222,"Significant":11,"Expected":13.41,"Rank in p.value_classic":4060,"p.value_elim":0.7895,"p.value_classic":0.79218,"genes":"ATF5,ATP1B2,DAB1,EPHB3,KIF26A,LRRK2,MDGA1,RTN4RL1,SEMA6B,TACC2,WDR62"} {"GO.ID":"GO:0046488","Term":"phosphatidylinositol metabolic process","Annotated":147,"Significant":7,"Expected":8.88,"Rank in p.value_classic":4058,"p.value_elim":0.78973,"p.value_classic":0.79189,"genes":"CDS1,CISH,LCLAT1,PLEK,SOCS1,TMEM150A,TNFAIP8L3"} {"GO.ID":"GO:0030041","Term":"actin filament polymerization","Annotated":147,"Significant":7,"Expected":8.88,"Rank in p.value_classic":4059,"p.value_elim":0.78973,"p.value_classic":0.79189,"genes":"FAM107A,JAK2,MSRB1,PSTPIP2,SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0099173","Term":"postsynapse organization","Annotated":166,"Significant":8,"Expected":10.03,"Rank in p.value_classic":4061,"p.value_elim":0.78989,"p.value_classic":0.79219,"genes":"COLQ,DTNBP1,EPHB3,GHRL,INA,LRRK2,NRCAM,NRP1"} {"GO.ID":"GO:0051049","Term":"regulation of transport","Annotated":1255,"Significant":103,"Expected":75.8,"Rank in p.value_classic":473,"p.value_elim":0.79131,"p.value_classic":0.00069,"genes":"ABCB1,ACSL1,ADAM8,ADORA3,AGT,ANK2,APPL2,ASIC1,ATP13A2,ATP1B2,ATP8B1,B2M,C2,C3,C4A,C4B,CADPS2,CAMK2D,CCL5,CD300LF,CD38,CD74,CDK1,CEACAM1,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,DAB2,DERL3,DLL1,DTNBP1,DYSF,EDN1,EEPD1,ERC2,F2RL3,FCN1,GHRL,HCAR2,HLA-DRB1,HLA-F,IFI27,IL12A,IL15,IL15RA,JAK2,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LRP5,LRRK2,LYN,MCTP2,MERTK,MMP9,MYOF,NECAB2,NOD2,NPR1,NR4A3,NRP1,OAS2,OSBPL6,OSM,P2RX4,P2RX7,PDE4B,PID1,PIM1,PLPP4,PLSCR1,PML,PRRT2,RSAD2,S100A10,SCIN,SCN4B,SEPTIN4,SIDT2,SLAMF1,SLC11A1,SLC31A2,SPTBN4,SRI,STAP1,STX1A,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TESC,TGM2,TIFAB,TNFRSF11A,TRDN,TTC39B,VEGFC,ZC3H12A"} {"GO.ID":"GO:0045834","Term":"positive regulation of lipid metabolic process","Annotated":89,"Significant":4,"Expected":5.38,"Rank in p.value_classic":4062,"p.value_elim":0.79187,"p.value_classic":0.79353,"genes":"CD74,DAB2,NR4A3,SLC45A3"} {"GO.ID":"GO:0070647","Term":"protein modification by small protein conjugation or removal","Annotated":829,"Significant":45,"Expected":50.07,"Rank in p.value_classic":4076,"p.value_elim":0.79231,"p.value_classic":0.79763,"genes":"AMER1,ASB2,BRCA1,CCNF,CDCA3,CISH,CYLD,DTL,DTX3L,EGR2,EPAS1,FAM107A,FBXO6,FEM1C,IFI27,IFIH1,JADE2,LRRK2,MAD2L1,MEFV,NMI,NOD2,NUB1,OTUD1,PARP10,PML,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SOCS1,STAMBPL1,STX1A,TANK,TRIM17,TRIM22,TRIM31,TRIM69,UBD,UBE2L6,UBE2T,UHRF1,WWP1,ZC3H12A"} {"GO.ID":"GO:0048863","Term":"stem cell differentiation","Annotated":204,"Significant":10,"Expected":12.32,"Rank in p.value_classic":4063,"p.value_elim":0.79233,"p.value_classic":0.79488,"genes":"EDN1,EPOP,HESX1,KITLG,LBH,NRP1,OSM,SEMA6B,SOX17,TAL1"} {"GO.ID":"GO:0009132","Term":"nucleoside diphosphate metabolic process","Annotated":109,"Significant":5,"Expected":6.58,"Rank in p.value_classic":4070,"p.value_elim":0.79347,"p.value_classic":0.7953,"genes":"AK1,CMPK2,P2RX7,RRM2,SLC2A6"} {"GO.ID":"GO:0060390","Term":"regulation of SMAD protein signal transduction","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4064,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"DAB2,JAK2"} {"GO.ID":"GO:0009299","Term":"mRNA transcription","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4065,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"EPAS1,S100A10"} {"GO.ID":"GO:0098927","Term":"vesicle-mediated transport between endosomal compartments","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4066,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"DAB2,LMTK2"} {"GO.ID":"GO:0010596","Term":"negative regulation of endothelial cell migration","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4067,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"KLF4,MIR503"} {"GO.ID":"GO:0042733","Term":"embryonic digit morphogenesis","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4068,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"BCL2L11,LRP5"} {"GO.ID":"GO:0071168","Term":"protein localization to chromatin","Annotated":48,"Significant":2,"Expected":2.9,"Rank in p.value_classic":4069,"p.value_elim":0.79396,"p.value_classic":0.79515,"genes":"ESCO2,TONSL"} {"GO.ID":"GO:0050679","Term":"positive regulation of epithelial cell proliferation","Annotated":167,"Significant":8,"Expected":10.09,"Rank in p.value_classic":4071,"p.value_elim":0.79529,"p.value_classic":0.79756,"genes":"CCL5,GHRL,IQGAP3,MIR503,NOD2,NR4A3,NRP1,VEGFC"} {"GO.ID":"GO:0045216","Term":"cell-cell junction organization","Annotated":167,"Significant":8,"Expected":10.09,"Rank in p.value_classic":4072,"p.value_elim":0.79529,"p.value_classic":0.79756,"genes":"AGT,ANK2,CDH5,CXADR,FSCN1,GJD3,MARVELD2,MTSS1"} {"GO.ID":"GO:0045861","Term":"negative regulation of proteolysis","Annotated":167,"Significant":8,"Expected":10.09,"Rank in p.value_classic":4073,"p.value_elim":0.79529,"p.value_classic":0.79756,"genes":"CARD16,CHAC1,KLF4,LAMP3,LRRK2,MMP9,PML,SERPING1"} {"GO.ID":"GO:0006606","Term":"protein import into nucleus","Annotated":148,"Significant":7,"Expected":8.94,"Rank in p.value_classic":4074,"p.value_elim":0.79544,"p.value_classic":0.79758,"genes":"APPL2,CDK1,JAK2,KPNA5,LRRK2,PML,ZC3H12A"} {"GO.ID":"GO:0007219","Term":"Notch signaling pathway","Annotated":148,"Significant":7,"Expected":8.94,"Rank in p.value_classic":4075,"p.value_elim":0.79544,"p.value_classic":0.79758,"genes":"BCL6,CHAC1,DLL1,DTX3L,MAML3,NOD2,TSPAN15"} {"GO.ID":"GO:0006906","Term":"vesicle fusion","Annotated":108,"Significant":9,"Expected":6.52,"Rank in p.value_classic":1873,"p.value_elim":0.79582,"p.value_classic":0.20475,"genes":"ATP13A2,CHMP4C,ERC2,PRRT2,RAB20,SLAMF1,STX11,STX1A,SYT1"} {"GO.ID":"GO:0048589","Term":"developmental growth","Annotated":531,"Significant":28,"Expected":32.07,"Rank in p.value_classic":4081,"p.value_elim":0.79632,"p.value_classic":0.80046,"genes":"AGR2,ATF5,BCL2L11,CDK1,COLQ,COMP,CSF1,DLL1,EDN1,FSTL4,G6PC1,GHRL,GINS1,HESX1,IL7,NCAPG2,NRCAM,NRN1,NRP1,PIM1,S1PR1,SEMA6B,SGPL1,SPTBN4,SYT1,TNFAIP6,TYMS,XRCC2"} {"GO.ID":"GO:0008360","Term":"regulation of cell shape","Annotated":129,"Significant":6,"Expected":7.79,"Rank in p.value_classic":4077,"p.value_elim":0.7968,"p.value_classic":0.79877,"genes":"CCL13,CCL7,FGD5,FMNL2,ITGA7,PLXNA2"} {"GO.ID":"GO:0009913","Term":"epidermal cell differentiation","Annotated":129,"Significant":6,"Expected":7.79,"Rank in p.value_classic":4078,"p.value_elim":0.7968,"p.value_classic":0.79877,"genes":"DLL1,KLF4,MAFF,OVOL1,PLAAT4,SLC4A7"} {"GO.ID":"GO:0071772","Term":"response to BMP","Annotated":129,"Significant":6,"Expected":7.79,"Rank in p.value_classic":4079,"p.value_elim":0.7968,"p.value_classic":0.79877,"genes":"CDH5,CHRD,COMP,FSTL4,HTRA1,TNFAIP6"} {"GO.ID":"GO:0071773","Term":"cellular response to BMP stimulus","Annotated":129,"Significant":6,"Expected":7.79,"Rank in p.value_classic":4080,"p.value_elim":0.7968,"p.value_classic":0.79877,"genes":"CDH5,CHRD,COMP,FSTL4,HTRA1,TNFAIP6"} {"GO.ID":"GO:0034329","Term":"cell junction assembly","Annotated":352,"Significant":18,"Expected":21.26,"Rank in p.value_classic":4087,"p.value_elim":0.79748,"p.value_classic":0.80081,"genes":"AGT,ANK2,CDH5,COLQ,EPHB3,FAM107A,FSCN1,GABRA3,GHRL,GJD3,LGI2,MARVELD2,MDGA1,NRCAM,NRP1,RAPGEF2,S100A10,THBS2"} {"GO.ID":"GO:0007389","Term":"pattern specification process","Annotated":334,"Significant":17,"Expected":20.17,"Rank in p.value_classic":4088,"p.value_elim":0.79805,"p.value_classic":0.80128,"genes":"ASB2,BHLHE41,C3,CHRD,DLL1,DNAAF1,EDN1,EGR2,IFT122,LRP5,MICAL2,NRP1,PLXNA2,SOX17,SSBP3,TIFAB,XRCC2"} {"GO.ID":"GO:0001666","Term":"response to hypoxia","Annotated":261,"Significant":13,"Expected":15.76,"Rank in p.value_classic":4089,"p.value_elim":0.79875,"p.value_classic":0.80159,"genes":"ADAM8,ASCL2,CCNA2,CD38,CYP1A1,CYSLTR1,EDN1,EPAS1,LTA,PMAIP1,PML,VCAM1,VEGFC"} {"GO.ID":"GO:0099175","Term":"regulation of postsynapse organization","Annotated":90,"Significant":4,"Expected":5.44,"Rank in p.value_classic":4082,"p.value_elim":0.79903,"p.value_classic":0.80065,"genes":"DTNBP1,GHRL,LRRK2,NRCAM"} {"GO.ID":"GO:0060840","Term":"artery development","Annotated":90,"Significant":4,"Expected":5.44,"Rank in p.value_classic":4083,"p.value_elim":0.79903,"p.value_classic":0.80065,"genes":"COMP,EDN1,EGR2,NRP1"} {"GO.ID":"GO:0042471","Term":"ear morphogenesis","Annotated":90,"Significant":4,"Expected":5.44,"Rank in p.value_classic":4084,"p.value_elim":0.79903,"p.value_classic":0.80065,"genes":"EDN1,HESX1,SOBP,TIFAB"} {"GO.ID":"GO:0045445","Term":"myoblast differentiation","Annotated":90,"Significant":4,"Expected":5.44,"Rank in p.value_classic":4085,"p.value_elim":0.79903,"p.value_classic":0.80065,"genes":"CXCL10,CXCL9,DLL1,EPAS1"} {"GO.ID":"GO:0098773","Term":"skin epidermis development","Annotated":90,"Significant":4,"Expected":5.44,"Rank in p.value_classic":4086,"p.value_elim":0.79903,"p.value_classic":0.80065,"genes":"DLL1,EDA,KLF4,STMN1"} {"GO.ID":"GO:0003014","Term":"renal system process","Annotated":83,"Significant":7,"Expected":5.01,"Rank in p.value_classic":1995,"p.value_elim":0.79944,"p.value_classic":0.23457,"genes":"ABCG2,AGT,CTNS,EDN1,NPR1,SLC12A3,SUCNR1"} {"GO.ID":"GO:0070482","Term":"response to oxygen levels","Annotated":298,"Significant":15,"Expected":18,"Rank in p.value_classic":4104,"p.value_elim":0.79989,"p.value_classic":0.80292,"genes":"ADAM8,ASCL2,CCNA2,CD38,CYP1A1,CYSLTR1,EDN1,EPAS1,FAS,LTA,PMAIP1,PML,POLB,VCAM1,VEGFC"} {"GO.ID":"GO:0072521","Term":"purine-containing compound metabolic process","Annotated":479,"Significant":25,"Expected":28.93,"Rank in p.value_classic":4116,"p.value_elim":0.80104,"p.value_classic":0.80491,"genes":"ABCG2,ACOT4,ACSL1,AK1,CD38,CTNS,DGAT2,ENPP4,G6PC1,GIMAP7,GTPBP1,IDO1,IDO2,LRRK2,NPR1,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,PRTFDC1,SLC2A6,SLC4A7,VPS9D1"} {"GO.ID":"GO:1904994","Term":"regulation of leukocyte adhesion to vascular endothelial cell","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4090,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"KLF4"} {"GO.ID":"GO:0060441","Term":"epithelial tube branching involved in lung morphogenesis","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4091,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"CELSR1"} {"GO.ID":"GO:0006921","Term":"cellular component disassembly involved in execution phase of apoptosis","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4092,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"TOP2A"} {"GO.ID":"GO:0010863","Term":"positive regulation of phospholipase C activity","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4093,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"ITK"} {"GO.ID":"GO:0010592","Term":"positive regulation of lamellipodium assembly","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4094,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"FSCN1"} {"GO.ID":"GO:0033137","Term":"negative regulation of peptidyl-serine phosphorylation","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4095,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"HGF"} {"GO.ID":"GO:0048261","Term":"negative regulation of receptor-mediated endocytosis","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4096,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"NECAB2"} {"GO.ID":"GO:0006346","Term":"DNA methylation-dependent heterochromatin formation","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4097,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"HELLS"} {"GO.ID":"GO:0006308","Term":"DNA catabolic process","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4098,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"ISG20"} {"GO.ID":"GO:0098868","Term":"bone growth","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4099,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"COMP"} {"GO.ID":"GO:0048668","Term":"collateral sprouting","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4100,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"FSTL4"} {"GO.ID":"GO:0035886","Term":"vascular associated smooth muscle cell differentiation","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4101,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"COMP"} {"GO.ID":"GO:1901889","Term":"negative regulation of cell junction assembly","Annotated":26,"Significant":1,"Expected":1.57,"Rank in p.value_classic":4102,"p.value_elim":0.80152,"p.value_classic":0.80236,"genes":"FAM107A"} {"GO.ID":"GO:0032418","Term":"lysosome localization","Annotated":70,"Significant":3,"Expected":4.23,"Rank in p.value_classic":4105,"p.value_elim":0.80172,"p.value_classic":0.80314,"genes":"LYN,NR4A3,S100A13"} {"GO.ID":"GO:1990849","Term":"vacuolar localization","Annotated":70,"Significant":3,"Expected":4.23,"Rank in p.value_classic":4106,"p.value_elim":0.80172,"p.value_classic":0.80314,"genes":"LYN,NR4A3,S100A13"} {"GO.ID":"GO:0006835","Term":"dicarboxylic acid transport","Annotated":70,"Significant":3,"Expected":4.23,"Rank in p.value_classic":4107,"p.value_elim":0.80172,"p.value_classic":0.80314,"genes":"DTNBP1,KCNJ10,P2RX7"} {"GO.ID":"GO:0072006","Term":"nephron development","Annotated":130,"Significant":6,"Expected":7.85,"Rank in p.value_classic":4115,"p.value_elim":0.80274,"p.value_classic":0.80468,"genes":"AGT,CTNS,DLL1,EDN1,MTSS1,STAT1"} {"GO.ID":"GO:0051606","Term":"detection of stimulus","Annotated":163,"Significant":11,"Expected":9.84,"Rank in p.value_classic":2476,"p.value_elim":0.80315,"p.value_classic":0.39668,"genes":"C4B,CDS1,CLEC6A,HLA-A,HLA-B,HLA-DRB1,NOD2,OR2I1P,PKD1L3,RTP4,SYT1"} {"GO.ID":"GO:0060191","Term":"regulation of lipase activity","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4109,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"CCL5,ITK"} {"GO.ID":"GO:0034332","Term":"adherens junction organization","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4110,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"CDH5,MTSS1"} {"GO.ID":"GO:0043470","Term":"regulation of carbohydrate catabolic process","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4111,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0070830","Term":"bicellular tight junction assembly","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4112,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"CDH5,MARVELD2"} {"GO.ID":"GO:0071470","Term":"cellular response to osmotic stress","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4113,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"RELB,TIFAB"} {"GO.ID":"GO:0007631","Term":"feeding behavior","Annotated":49,"Significant":2,"Expected":2.96,"Rank in p.value_classic":4114,"p.value_elim":0.80336,"p.value_classic":0.80452,"genes":"GHRL,NR4A3"} {"GO.ID":"GO:0022409","Term":"positive regulation of cell-cell adhesion","Annotated":269,"Significant":45,"Expected":16.25,"Rank in p.value_classic":117,"p.value_elim":0.80337,"p.value_classic":3.7e-10,"genes":"ADAM8,B2M,BCL6,BTN2A2,CCL5,CD274,CD28,CD74,CD80,CD83,CYLD,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-G,IL12A,IL12RB1,IL15,IL4I1,IL7,JAK2,KITLG,KLRK1,LYN,NOD2,NR4A3,PDCD1LG2,PTPRU,RIPK2,SLAMF1,SOCS1,TNFRSF14,TNFSF13B,VCAM1"} {"GO.ID":"GO:0009792","Term":"embryo development ending in birth or egg hatching","Annotated":569,"Significant":30,"Expected":34.37,"Rank in p.value_classic":4117,"p.value_elim":0.80368,"p.value_classic":0.80788,"genes":"AMOT,ASCL2,BCL2L11,BRCA1,CELSR1,CENPU,CHRD,DLL1,E2F8,EDN1,EPAS1,GINS1,HORMAD1,IFT122,KLF4,MAFF,NCAPG2,NPM2,PCDH12,PLCD3,PLPP4,PLXNA2,POLB,RRM2,SCO2,SH3PXD2A,SOX17,SSBP3,XRCC2,XYLT1"} {"GO.ID":"GO:0051056","Term":"regulation of small GTPase mediated signal transduction","Annotated":281,"Significant":14,"Expected":16.97,"Rank in p.value_classic":4119,"p.value_elim":0.80535,"p.value_classic":0.80824,"genes":"AMOT,BCL6,CSF1,F2RL3,FAM13A,FGD5,ITSN1,KITLG,MCF2L,NRP1,RASGRF1,STMN1,TAGAP,TGM2"} {"GO.ID":"GO:0008584","Term":"male gonad development","Annotated":111,"Significant":5,"Expected":6.7,"Rank in p.value_classic":4118,"p.value_elim":0.80628,"p.value_classic":0.80805,"genes":"BCL2L11,KITLG,RHOBTB3,SGPL1,TNFSF10"} {"GO.ID":"GO:0060173","Term":"limb development","Annotated":150,"Significant":7,"Expected":9.06,"Rank in p.value_classic":4120,"p.value_elim":0.80652,"p.value_classic":0.80859,"genes":"BCL2L11,CIBAR1,COMP,IFT122,KREMEN1,LRP5,PLXNA2"} {"GO.ID":"GO:0048736","Term":"appendage development","Annotated":150,"Significant":7,"Expected":9.06,"Rank in p.value_classic":4121,"p.value_elim":0.80652,"p.value_classic":0.80859,"genes":"BCL2L11,CIBAR1,COMP,IFT122,KREMEN1,LRP5,PLXNA2"} {"GO.ID":"GO:0001959","Term":"regulation of cytokine-mediated signaling pathway","Annotated":143,"Significant":23,"Expected":8.64,"Rank in p.value_classic":303,"p.value_elim":0.8072,"p.value_classic":0.00002,"genes":"CARD16,CASP4,CCL5,CD300LF,CD74,CSF1,CYLD,EDN1,IL1RN,IL7,IRF7,NLRC5,OAS3,PADI2,PARP14,PARP9,RIPK2,STAP1,STAT2,TANK,TICAM2,VRK2,ZBP1"} {"GO.ID":"GO:0006164","Term":"purine nucleotide biosynthetic process","Annotated":226,"Significant":11,"Expected":13.65,"Rank in p.value_classic":4123,"p.value_elim":0.80792,"p.value_classic":0.81047,"genes":"ACSL1,AK1,IDO1,IDO2,NPR1,PARP10,PARP9,PDK4,PID1,SLC4A7,VPS9D1"} {"GO.ID":"GO:0007281","Term":"germ cell development","Annotated":226,"Significant":11,"Expected":13.65,"Rank in p.value_classic":4124,"p.value_elim":0.80792,"p.value_classic":0.81047,"genes":"ADGB,DAZL,DMC1,EDN1,HORMAD1,NPM2,OCA2,PAQR5,PAQR8,TNFAIP6,ZMYND15"} {"GO.ID":"GO:0048568","Term":"embryonic organ development","Annotated":355,"Significant":18,"Expected":21.44,"Rank in p.value_classic":4128,"p.value_elim":0.80849,"p.value_classic":0.81172,"genes":"ASB2,ASCL2,DLL1,DNAAF1,E2F8,EDN1,EPAS1,FLT3LG,HESX1,IFT122,KITLG,MICAL2,PCDH12,PLCD3,SOBP,SOX17,TAL1,TIFAB"} {"GO.ID":"GO:0042552","Term":"myelination","Annotated":131,"Significant":6,"Expected":7.91,"Rank in p.value_classic":4122,"p.value_elim":0.80854,"p.value_classic":0.81046,"genes":"ANK2,EGR2,KCNJ10,SERINC5,TNFRSF21,TYMP"} {"GO.ID":"GO:0010232","Term":"vascular transport","Annotated":71,"Significant":3,"Expected":4.29,"Rank in p.value_classic":4125,"p.value_elim":0.80945,"p.value_classic":0.81084,"genes":"ABCB1,ABCG2,ATP1B2"} {"GO.ID":"GO:0150104","Term":"transport across blood-brain barrier","Annotated":71,"Significant":3,"Expected":4.29,"Rank in p.value_classic":4126,"p.value_elim":0.80945,"p.value_classic":0.81084,"genes":"ABCB1,ABCG2,ATP1B2"} {"GO.ID":"GO:0048708","Term":"astrocyte differentiation","Annotated":71,"Significant":3,"Expected":4.29,"Rank in p.value_classic":4127,"p.value_elim":0.80945,"p.value_classic":0.81084,"genes":"DAB1,DLL1,TAL1"} {"GO.ID":"GO:0051225","Term":"spindle assembly","Annotated":122,"Significant":9,"Expected":7.37,"Rank in p.value_classic":2254,"p.value_elim":0.80946,"p.value_classic":0.31681,"genes":"AURKB,BIRC5,CHMP4C,KIF11,KIF23,MYBL2,NDC80,PRC1,UHRF1"} {"GO.ID":"GO:0090174","Term":"organelle membrane fusion","Annotated":110,"Significant":9,"Expected":6.64,"Rank in p.value_classic":1926,"p.value_elim":0.80964,"p.value_classic":0.21972,"genes":"ATP13A2,CHMP4C,ERC2,PRRT2,RAB20,SLAMF1,STX11,STX1A,SYT1"} {"GO.ID":"GO:0031503","Term":"protein-containing complex localization","Annotated":170,"Significant":8,"Expected":10.27,"Rank in p.value_classic":4130,"p.value_elim":0.81087,"p.value_classic":0.81304,"genes":"BIRC5,EXOC3L1,EXOC3L4,IFT122,PML,RALB,SYNE1,TNFAIP2"} {"GO.ID":"GO:0022008","Term":"neurogenesis","Annotated":1387,"Significant":81,"Expected":83.77,"Rank in p.value_classic":3474,"p.value_elim":0.81128,"p.value_classic":0.64722,"genes":"APPL2,ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BCL6,BHLHE41,C21orf91,C3,CASZ1,CD38,CDK1,CDKN2C,CELSR1,CHAC1,CSF1,CX3CR1,CYSLTR1,DAB1,DAB2,DHFR,DLL1,DTNBP1,DYNLT1,EDN1,EGR2,EPHB3,EPOP,FSTL4,GHRL,GLDN,GPR183,GRIN3A,HAPLN3,IL15RA,JAK2,KCNJ10,KIF26A,KLF4,KREMEN1,LRRK2,LTA,LYN,MDGA1,MMD,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,P2RX4,PCDH12,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S100A10,S1PR1,SCARF1,SDC2,SEMA6B,SEPTIN4,SLC45A3,SLC4A7,SPTBN4,STAP1,STMN1,SYNE1,SYT1,TAL1,TGM2,TNFRSF21,TYRO3,VCAM1,VCAN,VEGFC,WDR62,WEE1,XRCC2"} {"GO.ID":"GO:0035306","Term":"positive regulation of dephosphorylation","Annotated":50,"Significant":2,"Expected":3.02,"Rank in p.value_classic":4131,"p.value_elim":0.81238,"p.value_classic":0.81352,"genes":"CDH5,PLEK"} {"GO.ID":"GO:0046546","Term":"development of primary male sexual characteristics","Annotated":112,"Significant":5,"Expected":6.76,"Rank in p.value_classic":4132,"p.value_elim":0.81245,"p.value_classic":0.81419,"genes":"BCL2L11,KITLG,RHOBTB3,SGPL1,TNFSF10"} {"GO.ID":"GO:0009218","Term":"pyrimidine ribonucleotide metabolic process","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4133,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"DPYS"} {"GO.ID":"GO:0060674","Term":"placenta blood vessel development","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4134,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"PLCD3"} {"GO.ID":"GO:0016486","Term":"peptide hormone processing","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4135,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"CTSL"} {"GO.ID":"GO:0097421","Term":"liver regeneration","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4136,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"TYMS"} {"GO.ID":"GO:2001032","Term":"regulation of double-strand break repair via nonhomologous end joining","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4137,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"PARP3"} {"GO.ID":"GO:0045116","Term":"protein neddylation","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4138,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"EPAS1"} {"GO.ID":"GO:0040036","Term":"regulation of fibroblast growth factor receptor signaling pathway","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4139,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"MIR503"} {"GO.ID":"GO:0060074","Term":"synapse maturation","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4140,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"CX3CR1"} {"GO.ID":"GO:0032965","Term":"regulation of collagen biosynthetic process","Annotated":27,"Significant":1,"Expected":1.63,"Rank in p.value_classic":4141,"p.value_elim":0.8135,"p.value_classic":0.81432,"genes":"CIITA"} {"GO.ID":"GO:0034976","Term":"response to endoplasmic reticulum stress","Annotated":246,"Significant":12,"Expected":14.86,"Rank in p.value_classic":4143,"p.value_elim":0.81372,"p.value_classic":0.81634,"genes":"AGR2,ATF3,BCL2L11,CASP4,CHAC1,DERL3,FBXO6,LRRK2,NOD2,PMAIP1,PML,RASGRF1"} {"GO.ID":"GO:0031397","Term":"negative regulation of protein ubiquitination","Annotated":72,"Significant":3,"Expected":4.35,"Rank in p.value_classic":4144,"p.value_elim":0.81692,"p.value_classic":0.81828,"genes":"DTX3L,MAD2L1,PARP10"} {"GO.ID":"GO:0061515","Term":"myeloid cell development","Annotated":72,"Significant":3,"Expected":4.35,"Rank in p.value_classic":4145,"p.value_elim":0.81692,"p.value_classic":0.81828,"genes":"ALAS1,BCL6,TAL1"} {"GO.ID":"GO:0032446","Term":"protein modification by small protein conjugation","Annotated":751,"Significant":40,"Expected":45.36,"Rank in p.value_classic":4149,"p.value_elim":0.81694,"p.value_classic":0.8216,"genes":"AMER1,ASB2,BRCA1,CCNF,CDCA3,CISH,DTL,DTX3L,EGR2,EPAS1,FAM107A,FBXO6,FEM1C,IFI27,IFIH1,JADE2,LRRK2,MAD2L1,MEFV,NMI,NOD2,NUB1,PARP10,PML,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SOCS1,STX1A,TRIM17,TRIM22,TRIM31,TRIM69,UBD,UBE2L6,UBE2T,UHRF1,WWP1"} {"GO.ID":"GO:0010717","Term":"regulation of epithelial to mesenchymal transition","Annotated":93,"Significant":4,"Expected":5.62,"Rank in p.value_classic":4147,"p.value_elim":0.81931,"p.value_classic":0.82085,"genes":"ADAM8,AGT,DAB2,GLIPR2"} {"GO.ID":"GO:0051224","Term":"negative regulation of protein transport","Annotated":93,"Significant":4,"Expected":5.62,"Rank in p.value_classic":4148,"p.value_elim":0.81931,"p.value_classic":0.82085,"genes":"DERL3,GHRL,IL12A,RSAD2"} {"GO.ID":"GO:0006790","Term":"sulfur compound metabolic process","Annotated":266,"Significant":13,"Expected":16.07,"Rank in p.value_classic":4154,"p.value_elim":0.81937,"p.value_classic":0.82205,"genes":"ACOT4,ACSL1,CHAC1,CTNS,DGAT2,DSE,GAL3ST4,GGT5,GSTK1,MICAL2,PDK4,SQOR,XYLT1"} {"GO.ID":"GO:0009790","Term":"embryo development","Annotated":928,"Significant":50,"Expected":56.05,"Rank in p.value_classic":4161,"p.value_elim":0.81969,"p.value_classic":0.82486,"genes":"AMOT,ASB2,ASCL2,BCL2L11,BRCA1,CDK1,CELSR1,CENPU,CHRD,DLL1,DNAAF1,E2F8,EDN1,EPAS1,FLT3LG,GINS1,HESX1,HORMAD1,IFT122,IL1RN,ITGA7,ITGB5,KITLG,KLF4,LAMB3,LRP5,MAFF,MICAL2,MMP9,NCAPG2,NPM2,NR4A3,NRP1,PCDH12,PLCD3,PLPP4,PLXNA2,POLB,RRM2,SCO2,SH3PXD2A,SOBP,SOX17,SSBP3,TAL1,TIFAB,TOP2A,VEGFC,XRCC2,XYLT1"} {"GO.ID":"GO:0008366","Term":"axon ensheathment","Annotated":133,"Significant":6,"Expected":8.03,"Rank in p.value_classic":4150,"p.value_elim":0.81975,"p.value_classic":0.8216,"genes":"ANK2,EGR2,KCNJ10,SERINC5,TNFRSF21,TYMP"} {"GO.ID":"GO:0036294","Term":"cellular response to decreased oxygen levels","Annotated":133,"Significant":6,"Expected":8.03,"Rank in p.value_classic":4151,"p.value_elim":0.81975,"p.value_classic":0.8216,"genes":"ADAM8,CCNA2,CYSLTR1,EDN1,EPAS1,PMAIP1"} {"GO.ID":"GO:0007272","Term":"ensheathment of neurons","Annotated":133,"Significant":6,"Expected":8.03,"Rank in p.value_classic":4152,"p.value_elim":0.81975,"p.value_classic":0.8216,"genes":"ANK2,EGR2,KCNJ10,SERINC5,TNFRSF21,TYMP"} {"GO.ID":"GO:0035148","Term":"tube formation","Annotated":133,"Significant":6,"Expected":8.03,"Rank in p.value_classic":4153,"p.value_elim":0.81975,"p.value_classic":0.8216,"genes":"BCL2L11,CELSR1,EDA,HESX1,IFT122,TGM2"} {"GO.ID":"GO:0008406","Term":"gonad development","Annotated":172,"Significant":8,"Expected":10.39,"Rank in p.value_classic":4159,"p.value_elim":0.82074,"p.value_classic":0.82285,"genes":"BCL2L11,DMC1,HESX1,KITLG,RHOBTB3,SGPL1,TNFAIP6,TNFSF10"} {"GO.ID":"GO:0045665","Term":"negative regulation of neuron differentiation","Annotated":51,"Significant":2,"Expected":3.08,"Rank in p.value_classic":4155,"p.value_elim":0.82102,"p.value_classic":0.82214,"genes":"B2M,DLL1"} {"GO.ID":"GO:0046902","Term":"regulation of mitochondrial membrane permeability","Annotated":51,"Significant":2,"Expected":3.08,"Rank in p.value_classic":4156,"p.value_elim":0.82102,"p.value_classic":0.82214,"genes":"BCL2L11,PMAIP1"} {"GO.ID":"GO:0033363","Term":"secretory granule organization","Annotated":51,"Significant":2,"Expected":3.08,"Rank in p.value_classic":4157,"p.value_elim":0.82102,"p.value_classic":0.82214,"genes":"DTNBP1,F2RL3"} {"GO.ID":"GO:0034661","Term":"ncRNA catabolic process","Annotated":51,"Significant":2,"Expected":3.08,"Rank in p.value_classic":4158,"p.value_elim":0.82102,"p.value_classic":0.82214,"genes":"XRN1,ZC3H12A"} {"GO.ID":"GO:0040013","Term":"negative regulation of locomotion","Annotated":286,"Significant":18,"Expected":17.27,"Rank in p.value_classic":2649,"p.value_elim":0.82198,"p.value_classic":0.46329,"genes":"ADORA3,ATP1B2,CD74,CHRD,CX3CR1,GHRL,IFITM1,KLF4,KLRK1,MIR503,NRP1,PADI2,PTGER4,PTPRU,SEMA6B,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0051170","Term":"import into nucleus","Annotated":153,"Significant":7,"Expected":9.24,"Rank in p.value_classic":4160,"p.value_elim":0.82227,"p.value_classic":0.82425,"genes":"APPL2,CDK1,JAK2,KPNA5,LRRK2,PML,ZC3H12A"} {"GO.ID":"GO:0080135","Term":"regulation of cellular response to stress","Annotated":486,"Significant":25,"Expected":29.35,"Rank in p.value_classic":4189,"p.value_elim":0.82259,"p.value_classic":0.82622,"genes":"AGR2,AIFM2,BCL2L11,BRCA1,CD74,CRHBP,DHFR,FAS,GCH1,KLF4,KREMEN1,LRRK2,LYN,MUC1,NOD2,PARP3,PMAIP1,PML,PYHIN1,RMI2,RTN4RL1,SCARF1,SCIMP,TIFAB,WDR76"} {"GO.ID":"GO:0060070","Term":"canonical Wnt signaling pathway","Annotated":267,"Significant":13,"Expected":16.13,"Rank in p.value_classic":4187,"p.value_elim":0.82331,"p.value_classic":0.82594,"genes":"AMER1,CYLD,DAB2,DKK2,EDA,EDN1,HESX1,KLF4,KREMEN1,LRP5,LRRK2,PTPRU,SOX17"} {"GO.ID":"GO:0032436","Term":"positive regulation of proteasomal ubiquitin-dependent protein catabolic process","Annotated":73,"Significant":3,"Expected":4.41,"Rank in p.value_classic":4163,"p.value_elim":0.82415,"p.value_classic":0.82548,"genes":"DAB2,LRRK2,NUB1"} {"GO.ID":"GO:0030901","Term":"midbrain development","Annotated":73,"Significant":3,"Expected":4.41,"Rank in p.value_classic":4164,"p.value_elim":0.82415,"p.value_classic":0.82548,"genes":"INA,PADI2,SYNGR3"} {"GO.ID":"GO:1905037","Term":"autophagosome organization","Annotated":114,"Significant":5,"Expected":6.89,"Rank in p.value_classic":4188,"p.value_elim":0.82431,"p.value_classic":0.82599,"genes":"ATP13A2,LRRK2,MAP1LC3C,RALB,RUFY4"} {"GO.ID":"GO:0001958","Term":"endochondral ossification","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4165,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"TMEM119"} {"GO.ID":"GO:0001945","Term":"lymph vessel development","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4166,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"VEGFC"} {"GO.ID":"GO:0035640","Term":"exploration behavior","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4167,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"LRRK2"} {"GO.ID":"GO:0060351","Term":"cartilage development involved in endochondral bone morphogenesis","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4168,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"COMP"} {"GO.ID":"GO:0045616","Term":"regulation of keratinocyte differentiation","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4169,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"PLAAT4"} {"GO.ID":"GO:0060325","Term":"face morphogenesis","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4170,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"SGPL1"} {"GO.ID":"GO:0043094","Term":"cellular metabolic compound salvage","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4171,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"PRTFDC1"} {"GO.ID":"GO:0090181","Term":"regulation of cholesterol metabolic process","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4172,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"TTC39B"} {"GO.ID":"GO:0072012","Term":"glomerulus vasculature development","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4173,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"EDN1"} {"GO.ID":"GO:0003351","Term":"epithelial cilium movement involved in extracellular fluid movement","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4174,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"DNAAF1"} {"GO.ID":"GO:0032373","Term":"positive regulation of sterol transport","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4175,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"EEPD1"} {"GO.ID":"GO:0032376","Term":"positive regulation of cholesterol transport","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4176,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"EEPD1"} {"GO.ID":"GO:0036075","Term":"replacement ossification","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4177,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"TMEM119"} {"GO.ID":"GO:1900274","Term":"regulation of phospholipase C activity","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4178,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"ITK"} {"GO.ID":"GO:1904357","Term":"negative regulation of telomere maintenance via telomere lengthening","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4179,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"XRN1"} {"GO.ID":"GO:0030970","Term":"retrograde protein transport, ER to cytosol","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4180,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"DERL3"} {"GO.ID":"GO:0036314","Term":"response to sterol","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4181,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"GRAMD1B"} {"GO.ID":"GO:0035136","Term":"forelimb morphogenesis","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4182,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"IFT122"} {"GO.ID":"GO:1901185","Term":"negative regulation of ERBB signaling pathway","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4183,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"MVP"} {"GO.ID":"GO:0006783","Term":"heme biosynthetic process","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4184,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"ALAS1"} {"GO.ID":"GO:1903513","Term":"endoplasmic reticulum to cytosol transport","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4185,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"DERL3"} {"GO.ID":"GO:0015868","Term":"purine ribonucleotide transport","Annotated":28,"Significant":1,"Expected":1.69,"Rank in p.value_classic":4186,"p.value_elim":0.82476,"p.value_classic":0.82556,"genes":"ANKH"} {"GO.ID":"GO:0030203","Term":"glycosaminoglycan metabolic process","Annotated":94,"Significant":4,"Expected":5.68,"Rank in p.value_classic":4190,"p.value_elim":0.82569,"p.value_classic":0.8272,"genes":"DSE,LYVE1,TNFAIP6,XYLT1"} {"GO.ID":"GO:0022900","Term":"electron transport chain","Annotated":154,"Significant":7,"Expected":9.3,"Rank in p.value_classic":4192,"p.value_elim":0.82729,"p.value_classic":0.82924,"genes":"AIFM2,CDK1,DHRS3,IDO1,NCF1,SCO2,STEAP4"} {"GO.ID":"GO:0044282","Term":"small molecule catabolic process","Annotated":287,"Significant":14,"Expected":17.33,"Rank in p.value_classic":4202,"p.value_elim":0.82859,"p.value_classic":0.83127,"genes":"ACOT4,APOBEC3A,APOBEC3D,APOBEC3G,CBR3,CYP1A1,ENPP4,GK,GLUL,IDO1,IDO2,IL4I1,LRP5,SCARF1"} {"GO.ID":"GO:0034030","Term":"ribonucleoside bisphosphate biosynthetic process","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4193,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"ACSL1,PDK4"} {"GO.ID":"GO:0034033","Term":"purine nucleoside bisphosphate biosynthetic process","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4194,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"ACSL1,PDK4"} {"GO.ID":"GO:0060350","Term":"endochondral bone morphogenesis","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4195,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"COMP,TMEM119"} {"GO.ID":"GO:0043113","Term":"receptor clustering","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4196,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"COLQ,TNFAIP6"} {"GO.ID":"GO:0033866","Term":"nucleoside bisphosphate biosynthetic process","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4197,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"ACSL1,PDK4"} {"GO.ID":"GO:1902475","Term":"L-alpha-amino acid transmembrane transport","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4198,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"KCNJ10,SLC11A1"} {"GO.ID":"GO:0043627","Term":"response to estrogen","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4199,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"CRHBP,GHRL"} {"GO.ID":"GO:1902895","Term":"positive regulation of miRNA transcription","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4200,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"AGT,KLF4"} {"GO.ID":"GO:0048645","Term":"animal organ formation","Annotated":52,"Significant":2,"Expected":3.14,"Rank in p.value_classic":4201,"p.value_elim":0.82931,"p.value_classic":0.8304,"genes":"PIM1,SOX17"} {"GO.ID":"GO:0000018","Term":"regulation of DNA recombination","Annotated":115,"Significant":5,"Expected":6.95,"Rank in p.value_classic":4203,"p.value_elim":0.83001,"p.value_classic":0.83166,"genes":"BCL6,CD28,PARP3,RMI2,TBX21"} {"GO.ID":"GO:0007601","Term":"visual perception","Annotated":115,"Significant":5,"Expected":6.95,"Rank in p.value_classic":4204,"p.value_elim":0.83001,"p.value_classic":0.83166,"genes":"CLIC5,DHRS3,EPAS1,GRM8,KCNJ10"} {"GO.ID":"GO:0045137","Term":"development of primary sexual characteristics","Annotated":174,"Significant":8,"Expected":10.51,"Rank in p.value_classic":4207,"p.value_elim":0.83021,"p.value_classic":0.83226,"genes":"BCL2L11,DMC1,HESX1,KITLG,RHOBTB3,SGPL1,TNFAIP6,TNFSF10"} {"GO.ID":"GO:0032006","Term":"regulation of TOR signaling","Annotated":135,"Significant":6,"Expected":8.15,"Rank in p.value_classic":4205,"p.value_elim":0.83043,"p.value_classic":0.83223,"genes":"CASTOR1,CTNS,DEPTOR,PIM1,SESN3,STAMBPL1"} {"GO.ID":"GO:0033157","Term":"regulation of intracellular protein transport","Annotated":135,"Significant":6,"Expected":8.15,"Rank in p.value_classic":4206,"p.value_elim":0.83043,"p.value_classic":0.83223,"genes":"ATP13A2,CDK1,DERL3,IFI27,JAK2,ZC3H12A"} {"GO.ID":"GO:0007422","Term":"peripheral nervous system development","Annotated":74,"Significant":3,"Expected":4.47,"Rank in p.value_classic":4208,"p.value_elim":0.83112,"p.value_classic":0.83243,"genes":"CDK1,EGR2,ONECUT2"} {"GO.ID":"GO:2000736","Term":"regulation of stem cell differentiation","Annotated":74,"Significant":3,"Expected":4.47,"Rank in p.value_classic":4209,"p.value_elim":0.83112,"p.value_classic":0.83243,"genes":"LBH,OSM,SOX17"} {"GO.ID":"GO:1901264","Term":"carbohydrate derivative transport","Annotated":74,"Significant":3,"Expected":4.47,"Rank in p.value_classic":4210,"p.value_elim":0.83112,"p.value_classic":0.83243,"genes":"ANKH,G6PC1,SLC37A1"} {"GO.ID":"GO:2000060","Term":"positive regulation of ubiquitin-dependent protein catabolic process","Annotated":95,"Significant":4,"Expected":5.74,"Rank in p.value_classic":4211,"p.value_elim":0.83188,"p.value_classic":0.83336,"genes":"DAB2,LRRK2,NUB1,PYHIN1"} {"GO.ID":"GO:0061387","Term":"regulation of extent of cell growth","Annotated":95,"Significant":4,"Expected":5.74,"Rank in p.value_classic":4212,"p.value_elim":0.83188,"p.value_classic":0.83336,"genes":"FSTL4,NRCAM,NRP1,SEMA6B"} {"GO.ID":"GO:0006006","Term":"glucose metabolic process","Annotated":155,"Significant":7,"Expected":9.36,"Rank in p.value_classic":4214,"p.value_elim":0.8322,"p.value_classic":0.83412,"genes":"ATF3,G6PC1,GHRL,LRP5,PDK4,PMAIP1,SLC45A3"} {"GO.ID":"GO:0031929","Term":"TOR signaling","Annotated":155,"Significant":7,"Expected":9.36,"Rank in p.value_classic":4215,"p.value_elim":0.8322,"p.value_classic":0.83412,"genes":"CASTOR1,CTNS,DEPTOR,PIM1,RHEBL1,SESN3,STAMBPL1"} {"GO.ID":"GO:0001654","Term":"eye development","Annotated":288,"Significant":14,"Expected":17.39,"Rank in p.value_classic":4216,"p.value_elim":0.83225,"p.value_classic":0.8349,"genes":"CTNS,CYP1A1,DLL1,DTNBP1,HESX1,IFT122,KLF4,LIMK2,LRP5,MAF,MERTK,NRP1,PLAAT3,SCO2"} {"GO.ID":"GO:0016567","Term":"protein ubiquitination","Annotated":669,"Significant":35,"Expected":40.4,"Rank in p.value_classic":4230,"p.value_elim":0.83325,"p.value_classic":0.83737,"genes":"AMER1,ASB2,BRCA1,CCNF,CDCA3,CISH,DTL,DTX3L,FAM107A,FBXO6,FEM1C,IFI27,JADE2,LRRK2,MAD2L1,MEFV,NMI,NOD2,NUB1,PARP10,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SOCS1,TRIM17,TRIM22,TRIM31,TRIM69,UBD,UBE2L6,UBE2T,UHRF1,WWP1"} {"GO.ID":"GO:0009416","Term":"response to light stimulus","Annotated":251,"Significant":12,"Expected":15.16,"Rank in p.value_classic":4226,"p.value_elim":0.83383,"p.value_classic":0.83628,"genes":"AURKB,CASP7,CDC25A,CDS1,CTNS,DTL,FEN1,IL12A,MMP9,PCLAF,PML,SYNE1"} {"GO.ID":"GO:0007610","Term":"behavior","Annotated":472,"Significant":24,"Expected":28.51,"Rank in p.value_classic":4231,"p.value_elim":0.83441,"p.value_classic":0.83781,"genes":"AIM2,ANKH,ASIC1,ATP1B2,B2M,C3orf70,CRHBP,CTNS,CX3CR1,DAB1,EGR2,FEN1,GHRL,IDO1,KCNJ10,LRRK2,NR4A3,P2RX4,RASGRF1,SELENOP,SOBP,SPTBN4,TAL1,TIFAB"} {"GO.ID":"GO:0065008","Term":"regulation of biological quality","Annotated":2201,"Significant":137,"Expected":132.93,"Rank in p.value_classic":2383,"p.value_elim":0.83471,"p.value_classic":0.35999,"genes":"ABCB1,AGR2,AGT,ANK2,ANO4,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,BCL2L11,CAMK2D,CCL13,CCL5,CCL7,CCRL2,CD38,CD40,CDH5,CEACAM1,COLQ,COMP,CRHBP,CTNS,CTSL,CTTNBP2,CX3CR1,CXADR,CXCR3,CYP1A1,CYSLTR1,DAB2,DAZL,DEPTOR,DGAT2,DHRS3,DHRS9,DLL1,DNM1,DTNBP1,DYNLT1,E2F1,EDN1,EGR2,ENPP4,EPAS1,EPHB3,ERAP2,ERC2,EXOC3L1,F2RL3,FAM107A,FGD5,FGL1,FMNL2,FSTL4,GABRA3,GCH1,GHRL,GJD3,GRIN3A,HCAR2,HLA-DRB1,HRH2,IL1RN,IL4I1,INSYN2A,IQGAP3,ITGA7,JAK2,KCNE5,KCNJ10,KCNJ2,LRP5,LRRK2,LYN,MDGA1,MERTK,NDC80,NOD2,NPR1,NRCAM,NRP1,OAS2,OCA2,OSM,P2RX4,P2RX7,PID1,PIM1,PLB1,PLEK,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PROK2,PRRT2,PTGER4,PYHIN1,RAB20,RAPGEF2,RASGRF1,SAMD4A,SCIN,SCN4B,SEMA6B,SERPING1,SGPL1,SIDT2,SLAMF8,SLC11A1,SLC12A3,SLC16A10,SLC2A5,SLC4A7,SOX17,SPTBN4,SRI,STAT1,STX1A,SUCNR1,SYNE1,TAPBP,TESC,THBD,THBS2,TIFAB,TMSB10,TRDN,TSPAN32,TYRO3,USP53,VEGFC,XKR6,ZC3H12A"} {"GO.ID":"GO:0007179","Term":"transforming growth factor beta receptor signaling pathway","Annotated":175,"Significant":8,"Expected":10.57,"Rank in p.value_classic":4227,"p.value_elim":0.8348,"p.value_classic":0.83682,"genes":"APPL2,CDH5,DAB2,HTRA1,ITGB5,ONECUT2,PML,PXN"} {"GO.ID":"GO:0044089","Term":"positive regulation of cellular component biogenesis","Annotated":436,"Significant":22,"Expected":26.33,"Rank in p.value_classic":4237,"p.value_elim":0.8353,"p.value_classic":0.83855,"genes":"AGT,ANLN,ATP13A2,BCL2L11,CDH5,EPHB3,FSCN1,GBP2,GBP5,GHRL,MTSS1,NRP1,P2RX7,PLEK,PPM1E,PXN,RALB,S100A10,TAL1,THBS2,TRABD2A,WARS1"} {"GO.ID":"GO:2001240","Term":"negative regulation of extrinsic apoptotic signaling pathway in absence of ligand","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4217,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"IL7"} {"GO.ID":"GO:0090317","Term":"negative regulation of intracellular protein transport","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4218,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"DERL3"} {"GO.ID":"GO:0098926","Term":"postsynaptic signal transduction","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4219,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"JAK2"} {"GO.ID":"GO:0030279","Term":"negative regulation of ossification","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4220,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"KREMEN1"} {"GO.ID":"GO:1901099","Term":"negative regulation of signal transduction in absence of ligand","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4221,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"IL7"} {"GO.ID":"GO:0003230","Term":"cardiac atrium development","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4222,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"ANK2"} {"GO.ID":"GO:0071404","Term":"cellular response to low-density lipoprotein particle stimulus","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4223,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"LPL"} {"GO.ID":"GO:0048854","Term":"brain morphogenesis","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4224,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"HESX1"} {"GO.ID":"GO:0006298","Term":"mismatch repair","Annotated":29,"Significant":1,"Expected":1.75,"Rank in p.value_classic":4225,"p.value_elim":0.83534,"p.value_classic":0.83611,"genes":"EXO1"} {"GO.ID":"GO:0009142","Term":"nucleoside triphosphate biosynthetic process","Annotated":116,"Significant":5,"Expected":7.01,"Rank in p.value_classic":4228,"p.value_elim":0.83556,"p.value_classic":0.83718,"genes":"AK1,CMPK2,PID1,TYMS,VPS9D1"} {"GO.ID":"GO:0050953","Term":"sensory perception of light stimulus","Annotated":116,"Significant":5,"Expected":7.01,"Rank in p.value_classic":4229,"p.value_elim":0.83556,"p.value_classic":0.83718,"genes":"CLIC5,DHRS3,EPAS1,GRM8,KCNJ10"} {"GO.ID":"GO:0055001","Term":"muscle cell development","Annotated":156,"Significant":7,"Expected":9.42,"Rank in p.value_classic":4238,"p.value_elim":0.837,"p.value_classic":0.83888,"genes":"ANK2,ASB2,CDK1,COMP,CXADR,EDN1,MYOZ2"} {"GO.ID":"GO:0009161","Term":"ribonucleoside monophosphate metabolic process","Annotated":53,"Significant":2,"Expected":3.2,"Rank in p.value_classic":4232,"p.value_elim":0.83725,"p.value_classic":0.83831,"genes":"AK1,DPYS"} {"GO.ID":"GO:0051058","Term":"negative regulation of small GTPase mediated signal transduction","Annotated":53,"Significant":2,"Expected":3.2,"Rank in p.value_classic":4233,"p.value_elim":0.83725,"p.value_classic":0.83831,"genes":"BCL6,STMN1"} {"GO.ID":"GO:0070918","Term":"regulatory ncRNA processing","Annotated":53,"Significant":2,"Expected":3.2,"Rank in p.value_classic":4234,"p.value_elim":0.83725,"p.value_classic":0.83831,"genes":"PIWIL4,TDRD9"} {"GO.ID":"GO:0071709","Term":"membrane assembly","Annotated":53,"Significant":2,"Expected":3.2,"Rank in p.value_classic":4235,"p.value_elim":0.83725,"p.value_classic":0.83831,"genes":"CHMP4C,S100A10"} {"GO.ID":"GO:0008631","Term":"intrinsic apoptotic signaling pathway in response to oxidative stress","Annotated":53,"Significant":2,"Expected":3.2,"Rank in p.value_classic":4236,"p.value_elim":0.83725,"p.value_classic":0.83831,"genes":"JAK2,PML"} {"GO.ID":"GO:0009141","Term":"nucleoside triphosphate metabolic process","Annotated":233,"Significant":11,"Expected":14.07,"Rank in p.value_classic":4245,"p.value_elim":0.83725,"p.value_classic":0.83957,"genes":"AK1,CMPK2,CTNS,GIMAP7,GTPBP1,LRRK2,P2RX7,PID1,SLC2A6,TYMS,VPS9D1"} {"GO.ID":"GO:0003007","Term":"heart morphogenesis","Annotated":214,"Significant":10,"Expected":12.92,"Rank in p.value_classic":4244,"p.value_elim":0.83729,"p.value_classic":0.83951,"genes":"ASB2,DHRS3,DLL1,DNAAF1,EDN1,MICAL2,NRP1,PIM1,S1PR1,SOX17"} {"GO.ID":"GO:0097061","Term":"dendritic spine organization","Annotated":75,"Significant":3,"Expected":4.53,"Rank in p.value_classic":4239,"p.value_elim":0.83786,"p.value_classic":0.83914,"genes":"DTNBP1,EPHB3,LRRK2"} {"GO.ID":"GO:0042472","Term":"inner ear morphogenesis","Annotated":75,"Significant":3,"Expected":4.53,"Rank in p.value_classic":4240,"p.value_elim":0.83786,"p.value_classic":0.83914,"genes":"HESX1,SOBP,TIFAB"} {"GO.ID":"GO:0006029","Term":"proteoglycan metabolic process","Annotated":75,"Significant":3,"Expected":4.53,"Rank in p.value_classic":4241,"p.value_elim":0.83786,"p.value_classic":0.83914,"genes":"DSE,GAL3ST4,XYLT1"} {"GO.ID":"GO:1902369","Term":"negative regulation of RNA catabolic process","Annotated":75,"Significant":3,"Expected":4.53,"Rank in p.value_classic":4242,"p.value_elim":0.83786,"p.value_classic":0.83914,"genes":"DAZL,E2F1,SLC11A1"} {"GO.ID":"GO:0090263","Term":"positive regulation of canonical Wnt signaling pathway","Annotated":96,"Significant":4,"Expected":5.8,"Rank in p.value_classic":4243,"p.value_elim":0.83788,"p.value_classic":0.83933,"genes":"AMER1,DKK2,EDA,LRRK2"} {"GO.ID":"GO:0050807","Term":"regulation of synapse organization","Annotated":195,"Significant":9,"Expected":11.78,"Rank in p.value_classic":4247,"p.value_elim":0.83791,"p.value_classic":0.84002,"genes":"COLQ,CTTNBP2,DTNBP1,EPHB3,GHRL,LRRK2,MDGA1,NRCAM,THBS2"} {"GO.ID":"GO:0019439","Term":"aromatic compound catabolic process","Annotated":510,"Significant":26,"Expected":30.8,"Rank in p.value_classic":4250,"p.value_elim":0.83945,"p.value_classic":0.84292,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CYP1A1,DAZL,DPYS,E2F1,ENPP4,EPHX1,FEN1,GTPBP1,IDO1,IDO2,IL4I1,ISG20,OAS2,P2RX7,PDE4B,SAMD4A,SIDT2,SLC11A1,SLC2A6,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:0007030","Term":"Golgi organization","Annotated":137,"Significant":6,"Expected":8.27,"Rank in p.value_classic":4248,"p.value_elim":0.8406,"p.value_classic":0.84233,"genes":"ATP8B1,CDK1,LRRK2,OPTN,SYNE1,USP6NL"} {"GO.ID":"GO:0007399","Term":"nervous system development","Annotated":1994,"Significant":115,"Expected":120.43,"Rank in p.value_classic":3812,"p.value_elim":0.84093,"p.value_classic":0.7253,"genes":"AATK,AIM2,ANK2,APPL2,ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BCL6,BHLHE41,C21orf91,C3,C3orf70,CASZ1,CD38,CDK1,CDKN2C,CELSR1,CENPF,CHAC1,CHRD,COLQ,CSF1,CTNS,CX3CR1,CYSLTR1,DAB1,DAB2,DHFR,DLL1,DTNBP1,DYNLT1,E2F1,EDN1,EGR2,EPHB3,EPOP,FSTL4,GABRA3,GFRA2,GHRL,GLDN,GPR183,GRIN3A,HAPLN3,HESX1,IFT122,IL15RA,INA,JAK2,KCNJ10,KIF26A,KLF4,KREMEN1,LGI2,LRP5,LRRK2,LTA,LYN,MARCKSL1,MDGA1,MERTK,MMD,NRCAM,NRGN,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,P2RX4,PADI2,PCDH12,PCDHGC3,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S100A10,S1PR1,SCARF1,SCIN,SDC2,SELENOP,SEMA6B,SEPTIN4,SERINC5,SLC45A3,SLC4A7,SOX17,SPTBN4,SSBP3,SSTR2,STAP1,STMN1,SYNE1,SYNGR3,SYT1,TACC2,TAL1,TGM2,THBS2,TIFAB,TNFRSF21,TYMP,TYRO3,VCAM1,VCAN,VEGFC,WDR62,WEE1,WWP1,XRCC2,ZC3H12A"} {"GO.ID":"GO:0019637","Term":"organophosphate metabolic process","Annotated":877,"Significant":50,"Expected":52.97,"Rank in p.value_classic":3648,"p.value_elim":0.84357,"p.value_classic":0.68962,"genes":"ACOT4,ACSL1,AK1,CD38,CDS1,CISH,CMPK2,CTNS,DGAT2,DPYS,ENPP2,G6PC1,GIMAP7,GK,GTPBP1,IDO1,IDO2,KARS1,LCLAT1,LPL,LRRK2,NAAA,NPR1,P2RX7,PARP10,PARP9,PCYT1A,PDE4B,PDK4,PID1,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PNPLA3,RRM2,SERINC5,SLC2A6,SLC4A7,SOCS1,TK1,TMEM150A,TNFAIP8L3,TYMP,TYMS,UNG,VPS9D1"} {"GO.ID":"GO:0000422","Term":"autophagy of mitochondrion","Annotated":97,"Significant":4,"Expected":5.86,"Rank in p.value_classic":4251,"p.value_elim":0.8437,"p.value_classic":0.84513,"genes":"ATP13A2,MAP1LC3C,NOD2,OPTN"} {"GO.ID":"GO:0120034","Term":"positive regulation of plasma membrane bounded cell projection assembly","Annotated":97,"Significant":4,"Expected":5.86,"Rank in p.value_classic":4252,"p.value_elim":0.8437,"p.value_classic":0.84513,"genes":"ANLN,FSCN1,NRP1,P2RX7"} {"GO.ID":"GO:0006970","Term":"response to osmotic stress","Annotated":76,"Significant":3,"Expected":4.59,"Rank in p.value_classic":4253,"p.value_elim":0.84437,"p.value_classic":0.84561,"genes":"ABCB1,RELB,TIFAB"} {"GO.ID":"GO:0033013","Term":"tetrapyrrole metabolic process","Annotated":54,"Significant":2,"Expected":3.26,"Rank in p.value_classic":4254,"p.value_elim":0.84485,"p.value_classic":0.84589,"genes":"ALAS1,CYP1A1"} {"GO.ID":"GO:0006081","Term":"cellular aldehyde metabolic process","Annotated":54,"Significant":2,"Expected":3.26,"Rank in p.value_classic":4255,"p.value_elim":0.84485,"p.value_classic":0.84589,"genes":"DAB2,HYI"} {"GO.ID":"GO:0006767","Term":"water-soluble vitamin metabolic process","Annotated":54,"Significant":2,"Expected":3.26,"Rank in p.value_classic":4256,"p.value_elim":0.84485,"p.value_classic":0.84589,"genes":"DHFR,MTHFD2"} {"GO.ID":"GO:0042987","Term":"amyloid precursor protein catabolic process","Annotated":54,"Significant":2,"Expected":3.26,"Rank in p.value_classic":4257,"p.value_elim":0.84485,"p.value_classic":0.84589,"genes":"GSAP,LYN"} {"GO.ID":"GO:0090162","Term":"establishment of epithelial cell polarity","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4258,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"AMOT"} {"GO.ID":"GO:0090169","Term":"regulation of spindle assembly","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4259,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"CHMP4C"} {"GO.ID":"GO:0140448","Term":"signaling receptor ligand precursor processing","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4260,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"CTSL"} {"GO.ID":"GO:0120178","Term":"steroid hormone biosynthetic process","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4261,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"DAB2"} {"GO.ID":"GO:0000578","Term":"embryonic axis specification","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4262,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"TIFAB"} {"GO.ID":"GO:0006084","Term":"acetyl-CoA metabolic process","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4263,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"PDK4"} {"GO.ID":"GO:0014888","Term":"striated muscle adaptation","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4264,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"MYOZ2"} {"GO.ID":"GO:0060632","Term":"regulation of microtubule-based movement","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4265,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"DNAAF1"} {"GO.ID":"GO:0055094","Term":"response to lipoprotein particle","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4266,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"LPL"} {"GO.ID":"GO:1903426","Term":"regulation of reactive oxygen species biosynthetic process","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4267,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"CTNS"} {"GO.ID":"GO:0097484","Term":"dendrite extension","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4268,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"SYT1"} {"GO.ID":"GO:0070979","Term":"protein K11-linked ubiquitination","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4269,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"UBE2T"} {"GO.ID":"GO:0045494","Term":"photoreceptor cell maintenance","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4270,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"ATP1B2"} {"GO.ID":"GO:0036258","Term":"multivesicular body assembly","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4271,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"CHMP4C"} {"GO.ID":"GO:0021696","Term":"cerebellar cortex morphogenesis","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4272,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"DLL1"} {"GO.ID":"GO:0000002","Term":"mitochondrial genome maintenance","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4273,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"TYMP"} {"GO.ID":"GO:0008535","Term":"respiratory chain complex IV assembly","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4274,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"SCO2"} {"GO.ID":"GO:0045879","Term":"negative regulation of smoothened signaling pathway","Annotated":30,"Significant":1,"Expected":1.81,"Rank in p.value_classic":4275,"p.value_elim":0.84528,"p.value_classic":0.84603,"genes":"IFT122"} {"GO.ID":"GO:0051173","Term":"positive regulation of nitrogen compound metabolic process","Annotated":2522,"Significant":156,"Expected":152.32,"Rank in p.value_classic":2439,"p.value_elim":0.84545,"p.value_classic":0.38069,"genes":"ABLIM3,ADAM8,AGT,AIM2,AMER1,ASCL2,ATF3,ATF5,AURKB,BACH1,BANK1,BAZ1A,BMAL2,BRCA1,C3,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDH5,CDK1,CDT1,CHTF18,CIITA,CLEC6A,CLSPN,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,DAB2,DAZL,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,ENPP2,EPAS1,FAM107A,FAM20A,FAS,FAXDC2,GCH1,GRAMD4,GSAP,GTPBP1,HBEGF,HGF,HLA-DRB1,IL12A,IL15,IL31RA,IL4I1,IQGAP3,IRF1,IRF4,IRF7,JAK2,KARS1,KITLG,KLF4,KLRK1,LBH,LILRA2,LIMK2,LITAF,LRP5,LRRK2,LYN,MAF,MAFF,MAML3,MEFV,MICAL2,MMD,MMP9,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OLIG1,ONECUT2,OSM,P2RX4,P2RX7,PARP14,PARP3,PARP9,PID1,PIM1,PKIB,PLSCR1,PMAIP1,PML,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RELB,RIPK2,S100A10,S1PR1,SAMD4A,SBNO2,SEPTIN4,SLC11A1,SOAT1,SOX17,SSBP3,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TLR7,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TRABD2A,TRIM22,TRIM31,UHRF1,VEGFC,WEE1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0050770","Term":"regulation of axonogenesis","Annotated":138,"Significant":6,"Expected":8.33,"Rank in p.value_classic":4276,"p.value_elim":0.8455,"p.value_classic":0.8472,"genes":"DAB1,EPHB3,FSTL4,NRP1,PLXNA2,SEMA6B"} {"GO.ID":"GO:0071702","Term":"organic substance transport","Annotated":1905,"Significant":111,"Expected":115.05,"Rank in p.value_classic":3631,"p.value_elim":0.84566,"p.value_classic":0.67914,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ADAM8,ADORA3,AGT,ANK2,ANKH,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARL4C,ATP13A2,ATP8B1,C1QTNF5,C3,CADPS2,CCL5,CD38,CD74,CDK1,CEACAM1,CENPF,CHMP4C,COMP,CRHBP,CTNS,DAB2,DERL3,DOP1A,DTNBP1,DTX3L,DYNLT1,EDN1,EEPD1,EGR2,EXOC3L1,FLVCR2,G6PC1,GHRL,GRAMD1B,GSDMD,HCAR2,HLA-DRB1,IFI27,IL12A,IL1RN,ITSN1,JAK2,KCNJ10,KPNA5,LMTK2,LRP5,LRRK2,LYN,MAP1LC3C,MCOLN2,MVP,NR4A3,OPTN,OSBPL6,P2RX4,P2RX7,PID1,PLEK,PLSCR1,PLSCR4,PML,RAB20,RBP7,RSAD2,S100A13,SERINC5,SIDT1,SIDT2,SLC11A1,SLC16A10,SLC18A1,SLC2A5,SLC2A6,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SNX10,SNX20,SOAT1,SRI,STX11,STX1A,SUCNR1,SYT1,SYT6,TAP1,TAP2,TESC,TGM2,TMEM144,TNFAIP8L3,TNFRSF11A,TTC39B,VAMP5,VEGFC,XKR6,ZC3H12A"} {"GO.ID":"GO:0051248","Term":"negative regulation of protein metabolic process","Annotated":710,"Significant":37,"Expected":42.88,"Rank in p.value_classic":4278,"p.value_elim":0.84584,"p.value_classic":0.84987,"genes":"AGT,ATP13A2,BANK1,CARD16,CEACAM1,CHAC1,DEPTOR,DHFR,DTNBP1,DTX3L,EDN1,HBEGF,HGF,JAK3,KLF4,LAMP3,LRP5,LRRK2,LYN,MAD2L1,MIR503,MMP9,MVP,NLRP12,PARP10,PARP14,PID1,PKIB,PML,PPM1E,SAMD4A,SERPING1,SOCS1,TYMS,WARS1,XRN1,ZC3H12A"} {"GO.ID":"GO:0060041","Term":"retina development in camera-type eye","Annotated":118,"Significant":5,"Expected":7.13,"Rank in p.value_classic":4277,"p.value_elim":0.84621,"p.value_classic":0.84778,"genes":"DLL1,DTNBP1,LRP5,MERTK,NRP1"} {"GO.ID":"GO:0034330","Term":"cell junction organization","Annotated":621,"Significant":32,"Expected":37.51,"Rank in p.value_classic":4281,"p.value_elim":0.8469,"p.value_classic":0.85064,"genes":"AGT,ANK2,C1QB,C3,CBLN3,CDH5,COLQ,CTTNBP2,CX3CR1,CXADR,DLGAP3,DTNBP1,EPHB3,ERC2,FAM107A,FSCN1,GABRA3,GHRL,GJD3,INA,LGI2,LRRK2,MARVELD2,MDGA1,MTSS1,NRCAM,NRP1,PCDHGC3,RAPGEF2,S100A10,SPTBN4,THBS2"} {"GO.ID":"GO:1901361","Term":"organic cyclic compound catabolic process","Annotated":531,"Significant":27,"Expected":32.07,"Rank in p.value_classic":4280,"p.value_elim":0.84713,"p.value_classic":0.85057,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CYP1A1,DAZL,DPYS,E2F1,ENPP4,FEN1,GTPBP1,HSD11B1,IDO1,IDO2,IL4I1,ISG20,OAS2,P2RX7,PDE4B,SAMD4A,SCARF1,SIDT2,SLC11A1,SLC2A6,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:1903076","Term":"regulation of protein localization to plasma membrane","Annotated":98,"Significant":4,"Expected":5.92,"Rank in p.value_classic":4282,"p.value_elim":0.84935,"p.value_classic":0.85075,"genes":"AGR2,DAB2,GBP1,PID1"} {"GO.ID":"GO:0033135","Term":"regulation of peptidyl-serine phosphorylation","Annotated":98,"Significant":4,"Expected":5.92,"Rank in p.value_classic":4283,"p.value_elim":0.84935,"p.value_classic":0.85075,"genes":"HGF,OSM,RIPK2,SPTBN4"} {"GO.ID":"GO:0050803","Term":"regulation of synapse structure or activity","Annotated":198,"Significant":9,"Expected":11.96,"Rank in p.value_classic":4284,"p.value_elim":0.8503,"p.value_classic":0.85231,"genes":"COLQ,CTTNBP2,DTNBP1,EPHB3,GHRL,LRRK2,MDGA1,NRCAM,THBS2"} {"GO.ID":"GO:0044088","Term":"regulation of vacuole organization","Annotated":55,"Significant":2,"Expected":3.32,"Rank in p.value_classic":4285,"p.value_elim":0.85213,"p.value_classic":0.85314,"genes":"LRRK2,RALB"} {"GO.ID":"GO:0120192","Term":"tight junction assembly","Annotated":55,"Significant":2,"Expected":3.32,"Rank in p.value_classic":4286,"p.value_elim":0.85213,"p.value_classic":0.85314,"genes":"CDH5,MARVELD2"} {"GO.ID":"GO:0006893","Term":"Golgi to plasma membrane transport","Annotated":55,"Significant":2,"Expected":3.32,"Rank in p.value_classic":4287,"p.value_elim":0.85213,"p.value_classic":0.85314,"genes":"OPTN,VAMP5"} {"GO.ID":"GO:0036293","Term":"response to decreased oxygen levels","Annotated":275,"Significant":13,"Expected":16.61,"Rank in p.value_classic":4289,"p.value_elim":0.85248,"p.value_classic":0.85485,"genes":"ADAM8,ASCL2,CCNA2,CD38,CYP1A1,CYSLTR1,EDN1,EPAS1,LTA,PMAIP1,PML,VCAM1,VEGFC"} {"GO.ID":"GO:0048699","Term":"generation of neurons","Annotated":1190,"Significant":64,"Expected":71.87,"Rank in p.value_classic":4304,"p.value_elim":0.85274,"p.value_classic":0.85791,"genes":"ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BCL6,C21orf91,C3,CASZ1,CD38,CELSR1,CX3CR1,DAB1,DAB2,DHFR,DLL1,DTNBP1,EDN1,EGR2,EPHB3,EPOP,FSTL4,GHRL,GLDN,GRIN3A,HAPLN3,IL15RA,JAK2,KIF26A,KLF4,KREMEN1,LRRK2,LYN,MDGA1,MMD,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,PCDH12,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S1PR1,SCARF1,SDC2,SEMA6B,SEPTIN4,SLC4A7,SPTBN4,STMN1,SYNE1,SYT1,TAL1,TNFRSF21,TYRO3,VCAM1,VCAN,VEGFC,WDR62,WEE1"} {"GO.ID":"GO:1901524","Term":"regulation of mitophagy","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4290,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"NOD2"} {"GO.ID":"GO:0000289","Term":"nuclear-transcribed mRNA poly(A) tail shortening","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4291,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"SAMD4A"} {"GO.ID":"GO:0002063","Term":"chondrocyte development","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4292,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"COMP"} {"GO.ID":"GO:0009583","Term":"detection of light stimulus","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4293,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"CDS1"} {"GO.ID":"GO:0051085","Term":"chaperone cofactor-dependent protein refolding","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4294,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"CD74"} {"GO.ID":"GO:0032366","Term":"intracellular sterol transport","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4295,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"GRAMD1B"} {"GO.ID":"GO:0051155","Term":"positive regulation of striated muscle cell differentiation","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4296,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"EDN1"} {"GO.ID":"GO:0001893","Term":"maternal placenta development","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4297,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"GHRL"} {"GO.ID":"GO:0036257","Term":"multivesicular body organization","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4298,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"CHMP4C"} {"GO.ID":"GO:0001662","Term":"behavioral fear response","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4299,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"ASIC1"} {"GO.ID":"GO:0006858","Term":"extracellular transport","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4300,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"DNAAF1"} {"GO.ID":"GO:0046676","Term":"negative regulation of insulin secretion","Annotated":31,"Significant":1,"Expected":1.87,"Rank in p.value_classic":4301,"p.value_elim":0.85462,"p.value_classic":0.85535,"genes":"GHRL"} {"GO.ID":"GO:0021915","Term":"neural tube development","Annotated":140,"Significant":6,"Expected":8.46,"Rank in p.value_classic":4302,"p.value_elim":0.85493,"p.value_classic":0.85657,"genes":"CELSR1,CHRD,IFT122,PLXNA2,SOX17,SSBP3"} {"GO.ID":"GO:0019827","Term":"stem cell population maintenance","Annotated":160,"Significant":7,"Expected":9.66,"Rank in p.value_classic":4303,"p.value_elim":0.85511,"p.value_classic":0.85687,"genes":"ASCL2,DLL1,HESX1,KLF4,LBH,LRP5,TAL1"} {"GO.ID":"GO:0046700","Term":"heterocycle catabolic process","Annotated":498,"Significant":25,"Expected":30.08,"Rank in p.value_classic":4306,"p.value_elim":0.85557,"p.value_classic":0.85876,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CYP1A1,DAZL,DPYS,E2F1,ENPP4,FEN1,GTPBP1,IDO1,IDO2,IL4I1,ISG20,OAS2,P2RX7,PDE4B,SAMD4A,SIDT2,SLC11A1,SLC2A6,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:1904951","Term":"positive regulation of establishment of protein localization","Annotated":276,"Significant":13,"Expected":16.67,"Rank in p.value_classic":4305,"p.value_elim":0.85585,"p.value_classic":0.85819,"genes":"ABLIM3,ADAM8,ATP13A2,CD38,CDK1,GHRL,HCAR2,HLA-DRB1,JAK2,P2RX7,SRI,VEGFC,ZC3H12A"} {"GO.ID":"GO:0035082","Term":"axoneme assembly","Annotated":56,"Significant":2,"Expected":3.38,"Rank in p.value_classic":4307,"p.value_elim":0.8591,"p.value_classic":0.86008,"genes":"DNAAF1,LRRC61"} {"GO.ID":"GO:0072698","Term":"protein localization to microtubule cytoskeleton","Annotated":56,"Significant":2,"Expected":3.38,"Rank in p.value_classic":4308,"p.value_elim":0.8591,"p.value_classic":0.86008,"genes":"SNX10,TRIM69"} {"GO.ID":"GO:0001655","Term":"urogenital system development","Annotated":56,"Significant":2,"Expected":3.38,"Rank in p.value_classic":4309,"p.value_elim":0.8591,"p.value_classic":0.86008,"genes":"EPHB3,HELLS"} {"GO.ID":"GO:0032880","Term":"regulation of protein localization","Annotated":752,"Significant":39,"Expected":45.42,"Rank in p.value_classic":4314,"p.value_elim":0.85946,"p.value_classic":0.86336,"genes":"ABLIM3,ADAM8,AGR2,ATP13A2,CCL5,CCNE2,CD38,CDK1,CYLD,DAB2,DERL3,DTX3L,EDN1,GBP1,GHRL,GLUL,HCAR2,HLA-DRB1,IFI27,IL12A,JAK2,LIMK2,LRP5,LRRK2,MMD,NECAB2,P2RX7,PARP9,PID1,PYHIN1,RSAD2,SIDT2,SRI,STX1A,TNFAIP6,TRIM17,TRIM22,VEGFC,ZC3H12A"} {"GO.ID":"GO:0018105","Term":"peptidyl-serine phosphorylation","Annotated":239,"Significant":11,"Expected":14.43,"Rank in p.value_classic":4310,"p.value_elim":0.85955,"p.value_classic":0.86167,"genes":"CAMK2D,CDK1,CLSPN,HGF,LMTK2,LRRK2,OSM,PRKX,RIPK2,SPTBN4,VRK2"} {"GO.ID":"GO:0070201","Term":"regulation of establishment of protein localization","Annotated":445,"Significant":22,"Expected":26.88,"Rank in p.value_classic":4313,"p.value_elim":0.86038,"p.value_classic":0.86331,"genes":"ABLIM3,ADAM8,ATP13A2,CCL5,CD38,CDK1,DERL3,GHRL,HCAR2,HLA-DRB1,IFI27,IL12A,JAK2,LRP5,LRRK2,P2RX7,RSAD2,SIDT2,SRI,STX1A,VEGFC,ZC3H12A"} {"GO.ID":"GO:0032879","Term":"regulation of localization","Annotated":1619,"Significant":121,"Expected":97.78,"Rank in p.value_classic":701,"p.value_elim":0.86093,"p.value_classic":0.00672,"genes":"ABCB1,ABLIM3,ACSL1,ADAM8,ADORA3,AGR2,AGT,ANK2,APPL2,ASIC1,ATP13A2,ATP1B2,ATP8B1,AURKB,B2M,BIRC5,C2,C3,C4A,C4B,CADPS2,CAMK2D,CCL5,CCNE2,CD300LF,CD38,CD74,CDK1,CEACAM1,CRHBP,CTSS,CXCL10,CXCL11,CXCL9,CYLD,DAB2,DERL3,DLL1,DTNBP1,DTX3L,DYSF,EDN1,EEPD1,ERC2,F2RL3,FCN1,GBP1,GHRL,GLUL,HCAR2,HLA-DRB1,HLA-F,IFI27,IL12A,IL15,IL15RA,JAK2,KCNE5,KCNJ10,KCNJ15,KCNJ2,LILRA2,LIMK2,LPL,LRP5,LRRK2,LYN,MCTP2,MERTK,MMD,MMP9,MYOF,NECAB2,NOD2,NPR1,NR4A3,NRP1,OAS2,OSBPL6,OSM,P2RX4,P2RX7,PARP9,PDE4B,PID1,PIM1,PLPP4,PLSCR1,PML,PRRT2,PYHIN1,RALB,RSAD2,S100A10,SCIN,SCN4B,SEPTIN4,SIDT2,SLAMF1,SLC11A1,SLC31A2,SPTBN4,SRI,STAP1,STX1A,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TESC,TGM2,TIFAB,TNFAIP6,TNFRSF11A,TRDN,TRIM17,TRIM22,TTC39B,VEGFC,ZC3H12A"} {"GO.ID":"GO:0035107","Term":"appendage morphogenesis","Annotated":121,"Significant":5,"Expected":7.31,"Rank in p.value_classic":4311,"p.value_elim":0.86112,"p.value_classic":0.86259,"genes":"BCL2L11,CIBAR1,IFT122,LRP5,PLXNA2"} {"GO.ID":"GO:0035108","Term":"limb morphogenesis","Annotated":121,"Significant":5,"Expected":7.31,"Rank in p.value_classic":4312,"p.value_elim":0.86112,"p.value_classic":0.86259,"genes":"BCL2L11,CIBAR1,IFT122,LRP5,PLXNA2"} {"GO.ID":"GO:0030516","Term":"regulation of axon extension","Annotated":79,"Significant":3,"Expected":4.77,"Rank in p.value_classic":4315,"p.value_elim":0.86254,"p.value_classic":0.8637,"genes":"NRCAM,NRP1,SEMA6B"} {"GO.ID":"GO:0006446","Term":"regulation of translational initiation","Annotated":79,"Significant":3,"Expected":4.77,"Rank in p.value_classic":4316,"p.value_elim":0.86254,"p.value_classic":0.8637,"genes":"BANK1,CCL5,DAZL"} {"GO.ID":"GO:1901879","Term":"regulation of protein depolymerization","Annotated":79,"Significant":3,"Expected":4.77,"Rank in p.value_classic":4317,"p.value_elim":0.86254,"p.value_classic":0.8637,"genes":"PLEK,SCIN,SPTBN4"} {"GO.ID":"GO:0002706","Term":"regulation of lymphocyte mediated immunity","Annotated":148,"Significant":31,"Expected":8.94,"Rank in p.value_classic":123,"p.value_elim":0.86339,"p.value_classic":8.2e-10,"genes":"B2M,BCL6,C3,CD1A,CD1C,CD28,CD80,CEACAM1,CR1L,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,IL4I1,KLRK1,LAG3,LTA,NOD2,P2RX7,PARP3,RSAD2,SLAMF1,SLAMF6,TAP2,TBX21"} {"GO.ID":"GO:0035633","Term":"maintenance of blood-brain barrier","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4318,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"CDH5"} {"GO.ID":"GO:0033014","Term":"tetrapyrrole biosynthetic process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4319,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ALAS1"} {"GO.ID":"GO:1903955","Term":"positive regulation of protein targeting to mitochondrion","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4320,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ABLIM3"} {"GO.ID":"GO:0003016","Term":"respiratory system process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4321,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ECEL1"} {"GO.ID":"GO:0003009","Term":"skeletal muscle contraction","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4322,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"KCNJ2"} {"GO.ID":"GO:0010712","Term":"regulation of collagen metabolic process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4323,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"CIITA"} {"GO.ID":"GO:0090279","Term":"regulation of calcium ion import","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4324,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"PLPP4"} {"GO.ID":"GO:0090207","Term":"regulation of triglyceride metabolic process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4325,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"C3"} {"GO.ID":"GO:0060563","Term":"neuroepithelial cell differentiation","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4326,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"DLL1"} {"GO.ID":"GO:0002209","Term":"behavioral defense response","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4327,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ASIC1"} {"GO.ID":"GO:0046329","Term":"negative regulation of JNK cascade","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4328,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"CYLD"} {"GO.ID":"GO:0071402","Term":"cellular response to lipoprotein particle stimulus","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4329,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"LPL"} {"GO.ID":"GO:0072210","Term":"metanephric nephron development","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4330,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"STAT1"} {"GO.ID":"GO:0050911","Term":"detection of chemical stimulus involved in sensory perception of smell","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4331,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"OR2I1P"} {"GO.ID":"GO:1903749","Term":"positive regulation of establishment of protein localization to mitochondrion","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4332,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ABLIM3"} {"GO.ID":"GO:0006779","Term":"porphyrin-containing compound biosynthetic process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4333,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"ALAS1"} {"GO.ID":"GO:0019320","Term":"hexose catabolic process","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4334,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"LRP5"} {"GO.ID":"GO:0008542","Term":"visual learning","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4335,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"CTNS"} {"GO.ID":"GO:0045773","Term":"positive regulation of axon extension","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4336,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"NRP1"} {"GO.ID":"GO:0045880","Term":"positive regulation of smoothened signaling pathway","Annotated":32,"Significant":1,"Expected":1.93,"Rank in p.value_classic":4337,"p.value_elim":0.8634,"p.value_classic":0.86411,"genes":"CIBAR1"} {"GO.ID":"GO:0034249","Term":"negative regulation of amide metabolic process","Annotated":142,"Significant":6,"Expected":8.58,"Rank in p.value_classic":4338,"p.value_elim":0.86388,"p.value_classic":0.86546,"genes":"BANK1,DHFR,MIR503,SAMD4A,TYMS,XRN1"} {"GO.ID":"GO:0050789","Term":"regulation of biological process","Annotated":8786,"Significant":599,"Expected":530.63,"Rank in p.value_classic":161,"p.value_elim":0.86397,"p.value_classic":2.9e-08,"genes":"ABCB1,ABLIM3,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AKAP7,AMER1,AMOT,ANK2,ANKH,ANLN,ANTXR1,APOBEC3A,APOBEC3D,APOBEC3G,APOL3,APPL2,ARAP2,ASB2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL2A1,BCL2L11,BCL2L14,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C1QB,C1R,C1RL,C1S,C2,C21orf91,C3,C3orf38,C4A,C4B,CADPS2,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CFB,CFH,CHAC1,CHMP4C,CHRD,CHTF18,CIBAR1,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,COLEC12,COLQ,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DAZL,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DNAAF1,DNM1,DRAM1,DSCC1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPOP,ERC2,ESCO2,ETV7,EXOC3L1,F2RL3,FAM107A,FAM13A,FAM20A,FAS,FAXDC2,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FMNL2,FSCN1,FSTL4,FYB1,G0S2,G6PC1,GABRA3,GADD45B,GAL3ST4,GAREM1,GBP1,GBP2,GBP3,GBP5,GBP7,GCH1,GFRA2,GHRL,GIMAP8,GJD3,GLDN,GLIPR2,GLUL,GNG2,GOLM1,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GSAP,GSDMD,GTPBP1,GTSE1,HAPLN3,HAVCR1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HIVEP2,HJURP,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSH2D,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ISG20,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JADE2,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ15,KCNJ2,KIF11,KIF18B,KIF23,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LACTB,LAG3,LAMP3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MARCKSL1,MCF2L,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MDGA1,MEFV,MERTK,MICAL2,MIR503,MKI67,MMD,MMP9,MRAS,MT2A,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYOF,MYOZ2,NCAPG,NCAPG2,NCAPH,NCF1,NDC80,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRP1,NUB1,NUCB1,NUF2,NUSAP1,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,OLIG1,ONECUT2,OPTN,OR2I1P,ORC1,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PARP3,PARP9,PCDHGC3,PCLAF,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PPM1E,PRC1,PRKX,PROK2,PRRT2,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF213,RRM2,RSAD2,RSU1,RTN4RL1,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCARF1,SCIMP,SCIN,SCN4B,SDC2,SECTM1,SELENOP,SEMA6B,SEPTIN4,SERPING1,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC12A3,SLC16A10,SLC20A1,SLC2A6,SLC31A2,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SPC24,SPC25,SPTBN4,SRI,SSBP3,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAGAP,TAL1,TANK,TAP2,TAPBP,TAPBPL,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM119,TMEM176A,TMEM176B,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRAFD1,TRDN,TRIM17,TRIM22,TRIM31,TSPAN15,TSPAN32,TTC39B,TYMP,TYMS,TYRO3,UBD,UHRF1,UNG,USP6NL,VCAM1,VCAN,VEGFC,VRK2,WARS1,WDR62,WDR76,WEE1,WWP1,XAF1,XRCC2,XRN1,ZBP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1,ZWINT"} {"GO.ID":"GO:1903828","Term":"negative regulation of protein localization","Annotated":182,"Significant":8,"Expected":10.99,"Rank in p.value_classic":4339,"p.value_elim":0.86423,"p.value_classic":0.86603,"genes":"DAB2,DERL3,GBP1,GHRL,IL12A,LRRK2,PID1,RSAD2"} {"GO.ID":"GO:0002709","Term":"regulation of T cell mediated immunity","Annotated":86,"Significant":22,"Expected":5.19,"Rank in p.value_classic":138,"p.value_elim":0.86535,"p.value_classic":4.8e-09,"genes":"B2M,CD1A,CD1C,CD80,CEACAM1,HLA-A,HLA-B,HLA-C,HLA-DRA,HLA-DRB1,HLA-E,HLA-F,HLA-G,IL12A,IL12RB1,IL4I1,NOD2,P2RX7,RSAD2,SLAMF1,TAP2,TBX21"} {"GO.ID":"GO:0044091","Term":"membrane biogenesis","Annotated":57,"Significant":2,"Expected":3.44,"Rank in p.value_classic":4340,"p.value_elim":0.86576,"p.value_classic":0.86672,"genes":"CHMP4C,S100A10"} {"GO.ID":"GO:0043297","Term":"apical junction assembly","Annotated":57,"Significant":2,"Expected":3.44,"Rank in p.value_classic":4341,"p.value_elim":0.86576,"p.value_classic":0.86672,"genes":"CDH5,MARVELD2"} {"GO.ID":"GO:0031122","Term":"cytoplasmic microtubule organization","Annotated":57,"Significant":2,"Expected":3.44,"Rank in p.value_classic":4342,"p.value_elim":0.86576,"p.value_classic":0.86672,"genes":"LIMK2,TRDN"} {"GO.ID":"GO:0050806","Term":"positive regulation of synaptic transmission","Annotated":122,"Significant":5,"Expected":7.37,"Rank in p.value_classic":4343,"p.value_elim":0.86581,"p.value_classic":0.86725,"genes":"CX3CR1,DTNBP1,FAM107A,STX1A,SYT1"} {"GO.ID":"GO:0071363","Term":"cellular response to growth factor stimulus","Annotated":575,"Significant":29,"Expected":34.73,"Rank in p.value_classic":4344,"p.value_elim":0.86585,"p.value_classic":0.86912,"genes":"AGT,APPL2,CCL5,CCNA2,CDH5,CHRD,COMP,CX3CR1,DAB2,DLL1,EDN1,FSTL4,GAREM1,HGF,HTRA1,IL12A,ITGB5,KLF4,MIR503,NRP1,ONECUT2,PML,PXN,RAPGEF2,SHCBP1,SLC4A7,TNFAIP6,VCAM1,VEGFC"} {"GO.ID":"GO:0019752","Term":"carboxylic acid metabolic process","Annotated":684,"Significant":35,"Expected":41.31,"Rank in p.value_classic":4348,"p.value_elim":0.86715,"p.value_classic":0.87071,"genes":"ACOT4,ACSL1,APPL2,ATP8B1,BRCA1,C3,CD74,CEACAM1,CYP1A1,DHFR,DHRS9,DSE,EDN1,EPHX1,GGT5,GLUL,HSD3B7,HYI,IDO1,IDO2,IL4I1,LPL,LTC4S,MTHFD2,NAAA,NR4A3,OCA2,OSBPL6,P2RX7,PDK4,PNPLA3,SERINC5,SGPL1,SLC2A6,SLC45A3"} {"GO.ID":"GO:0043436","Term":"oxoacid metabolic process","Annotated":702,"Significant":36,"Expected":42.4,"Rank in p.value_classic":4349,"p.value_elim":0.86718,"p.value_classic":0.87079,"genes":"ACOT4,ACSL1,ANKH,APPL2,ATP8B1,BRCA1,C3,CD74,CEACAM1,CYP1A1,DHFR,DHRS9,DSE,EDN1,EPHX1,GGT5,GLUL,HSD3B7,HYI,IDO1,IDO2,IL4I1,LPL,LTC4S,MTHFD2,NAAA,NR4A3,OCA2,OSBPL6,P2RX7,PDK4,PNPLA3,SERINC5,SGPL1,SLC2A6,SLC45A3"} {"GO.ID":"GO:0040029","Term":"epigenetic regulation of gene expression","Annotated":183,"Significant":8,"Expected":11.05,"Rank in p.value_classic":4347,"p.value_elim":0.86807,"p.value_classic":0.86983,"genes":"BAZ1A,BCL6,BRCA1,HELLS,PADI2,TDRD9,UHRF1,ZNFX1"} {"GO.ID":"GO:0009166","Term":"nucleotide catabolic process","Annotated":143,"Significant":6,"Expected":8.64,"Rank in p.value_classic":4345,"p.value_elim":0.86818,"p.value_classic":0.86973,"genes":"DPYS,P2RX7,PDE4B,SLC2A6,TYMP,UNG"} {"GO.ID":"GO:1902904","Term":"negative regulation of supramolecular fiber organization","Annotated":143,"Significant":6,"Expected":8.64,"Rank in p.value_classic":4346,"p.value_elim":0.86818,"p.value_classic":0.86973,"genes":"CDH5,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0051254","Term":"positive regulation of RNA metabolic process","Annotated":1549,"Significant":84,"Expected":93.55,"Rank in p.value_classic":4367,"p.value_elim":0.86862,"p.value_classic":0.87414,"genes":"ABLIM3,AGT,ASCL2,ATF3,ATF5,BACH1,BMAL2,BRCA1,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CIITA,CXCL10,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,GTPBP1,HGF,HLA-DRB1,IL31RA,IL4I1,IRF1,IRF4,IRF7,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,PARP9,PID1,PIM1,PLSCR1,PYHIN1,RELB,RIPK2,S100A10,S1PR1,SAMD4A,SBNO2,SLC11A1,SOX17,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TLR7,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0051493","Term":"regulation of cytoskeleton organization","Annotated":467,"Significant":23,"Expected":28.2,"Rank in p.value_classic":4358,"p.value_elim":0.86952,"p.value_classic":0.8724,"genes":"BRCA1,CCNF,CDH5,CELSR1,CHMP4C,CYLD,EDN1,FAM107A,FSCN1,MTSS1,NRP1,P2RX7,PARP3,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0006520","Term":"amino acid metabolic process","Annotated":242,"Significant":11,"Expected":14.62,"Rank in p.value_classic":4351,"p.value_elim":0.86975,"p.value_classic":0.87178,"genes":"CTNS,DHFR,GGT5,GLUL,IDO1,IDO2,IL4I1,KARS1,OCA2,SERINC5,WARS1"} {"GO.ID":"GO:0006022","Term":"aminoglycan metabolic process","Annotated":102,"Significant":4,"Expected":6.16,"Rank in p.value_classic":4350,"p.value_elim":0.87024,"p.value_classic":0.87152,"genes":"DSE,LYVE1,TNFAIP6,XYLT1"} {"GO.ID":"GO:0009896","Term":"positive regulation of catabolic process","Annotated":486,"Significant":24,"Expected":29.35,"Rank in p.value_classic":4366,"p.value_elim":0.87103,"p.value_classic":0.87394,"genes":"ADAM8,AMER1,CALCOCO2,DAB2,DEPTOR,DTL,DTX3L,GTPBP1,LRRK2,MEFV,NOD2,NUB1,OPTN,P2RX7,PYHIN1,RALB,RIPK2,RUFY4,SAMD4A,SESN3,SOX17,TPCN1,TRIM22,ZC3H12A"} {"GO.ID":"GO:0098727","Term":"maintenance of cell number","Annotated":164,"Significant":7,"Expected":9.9,"Rank in p.value_classic":4365,"p.value_elim":0.87155,"p.value_classic":0.87318,"genes":"ASCL2,DLL1,HESX1,KLF4,LBH,LRP5,TAL1"} {"GO.ID":"GO:0030513","Term":"positive regulation of BMP signaling pathway","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4352,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"CDH5"} {"GO.ID":"GO:0007031","Term":"peroxisome organization","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4353,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"PLAAT3"} {"GO.ID":"GO:0007164","Term":"establishment of tissue polarity","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4354,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"CELSR1"} {"GO.ID":"GO:0001736","Term":"establishment of planar polarity","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4355,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"CELSR1"} {"GO.ID":"GO:0016242","Term":"negative regulation of macroautophagy","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4356,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"LRRK2"} {"GO.ID":"GO:0097242","Term":"amyloid-beta clearance","Annotated":33,"Significant":1,"Expected":1.99,"Rank in p.value_classic":4357,"p.value_elim":0.87165,"p.value_classic":0.87234,"genes":"C3"} {"GO.ID":"GO:0061025","Term":"membrane fusion","Annotated":142,"Significant":10,"Expected":8.58,"Rank in p.value_classic":2365,"p.value_elim":0.87205,"p.value_classic":0.35479,"genes":"ATP13A2,CHMP4C,CTSL,ERC2,PRRT2,RAB20,SLAMF1,STX11,STX1A,SYT1"} {"GO.ID":"GO:0000423","Term":"mitophagy","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4359,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"NOD2,OPTN"} {"GO.ID":"GO:0170041","Term":"non-proteinogenic amino acid metabolic process","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4360,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"IDO1,IDO2"} {"GO.ID":"GO:0030239","Term":"myofibril assembly","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4361,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"EDN1,MYOZ2"} {"GO.ID":"GO:0061035","Term":"regulation of cartilage development","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4362,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"MAF,SCIN"} {"GO.ID":"GO:0046323","Term":"glucose import","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4363,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"APPL2,PID1"} {"GO.ID":"GO:0001707","Term":"mesoderm formation","Annotated":58,"Significant":2,"Expected":3.5,"Rank in p.value_classic":4364,"p.value_elim":0.87214,"p.value_classic":0.87307,"genes":"KLF4,TAL1"} {"GO.ID":"GO:0048041","Term":"focal adhesion assembly","Annotated":81,"Significant":3,"Expected":4.89,"Rank in p.value_classic":4368,"p.value_elim":0.8736,"p.value_classic":0.8747,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:0046031","Term":"ADP metabolic process","Annotated":81,"Significant":3,"Expected":4.89,"Rank in p.value_classic":4369,"p.value_elim":0.8736,"p.value_classic":0.8747,"genes":"AK1,P2RX7,SLC2A6"} {"GO.ID":"GO:0032535","Term":"regulation of cellular component size","Annotated":320,"Significant":15,"Expected":19.33,"Rank in p.value_classic":4372,"p.value_elim":0.87477,"p.value_classic":0.87706,"genes":"ATP13A2,DEPTOR,DNM1,EDN1,FSTL4,IQGAP3,NRCAM,NRP1,P2RX7,PLEK,SCIN,SEMA6B,SLC12A3,SPTBN4,TMSB10"} {"GO.ID":"GO:0009185","Term":"ribonucleoside diphosphate metabolic process","Annotated":103,"Significant":4,"Expected":6.22,"Rank in p.value_classic":4370,"p.value_elim":0.87505,"p.value_classic":0.8763,"genes":"AK1,P2RX7,RRM2,SLC2A6"} {"GO.ID":"GO:0048675","Term":"axon extension","Annotated":103,"Significant":4,"Expected":6.22,"Rank in p.value_classic":4371,"p.value_elim":0.87505,"p.value_classic":0.8763,"genes":"EDN1,NRCAM,NRP1,SEMA6B"} {"GO.ID":"GO:0006082","Term":"organic acid metabolic process","Annotated":706,"Significant":36,"Expected":42.64,"Rank in p.value_classic":4373,"p.value_elim":0.87519,"p.value_classic":0.87866,"genes":"ACOT4,ACSL1,ANKH,APPL2,ATP8B1,BRCA1,C3,CD74,CEACAM1,CYP1A1,DHFR,DHRS9,DSE,EDN1,EPHX1,GGT5,GLUL,HSD3B7,HYI,IDO1,IDO2,IL4I1,LPL,LTC4S,MTHFD2,NAAA,NR4A3,OCA2,OSBPL6,P2RX7,PDK4,PNPLA3,SERINC5,SGPL1,SLC2A6,SLC45A3"} {"GO.ID":"GO:0044281","Term":"small molecule metabolic process","Annotated":1445,"Significant":84,"Expected":87.27,"Rank in p.value_classic":3571,"p.value_elim":0.87553,"p.value_classic":0.66665,"genes":"ABCG2,ACOT4,ACSL1,AIFM2,AK1,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APPL2,ATF3,ATP8B1,BRCA1,C3,CA11,CBR3,CD38,CD74,CEACAM1,CMPK2,CTNS,CYP1A1,DAB2,DGAT2,DHFR,DHRS3,DHRS9,DPYS,DSE,EDN1,ENPP4,EPHX1,G6PC1,GCH1,GGT5,GHRL,GIMAP7,GK,GLUL,GTPBP1,HSD3B7,HYI,IDO1,IDO2,IL4I1,KARS1,LPL,LRP5,LRRK2,LTC4S,MTHFD2,NAAA,NPR1,NR4A3,OCA2,OSBPL6,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,PLAAT3,PLB1,PLEK,PMAIP1,PNPLA3,PRTFDC1,RRM2,SCARF1,SERINC5,SGPL1,SLC2A6,SLC45A3,SLC4A7,SOAT1,TK1,TTC39B,TYMP,TYMS,UNG,VPS9D1"} {"GO.ID":"GO:0009893","Term":"positive regulation of metabolic process","Annotated":3078,"Significant":215,"Expected":185.9,"Rank in p.value_classic":707,"p.value_elim":0.87701,"p.value_classic":0.00729,"genes":"ABLIM3,ACOD1,ACSL1,ADAM8,AGR2,AGT,AIM2,AMER1,ANK2,APPL2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BANK1,BAZ1A,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CALCOCO2,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDH5,CDK1,CDT1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,DAB2,DAZL,DEPTOR,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,FAM107A,FAM20A,FAS,FAXDC2,FCN1,G0S2,GBP5,GCH1,GHRL,GRAMD4,GSAP,GSDMD,GTPBP1,HBEGF,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MMD,MMP9,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDE4B,PID1,PIM1,PKIB,PLEK,PLSCR1,PMAIP1,PML,PSME1,PSME2,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RIPK2,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SEPTIN4,SESN3,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRIM22,TRIM31,TYRO3,UHRF1,VEGFC,WARS1,WEE1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0071560","Term":"cellular response to transforming growth factor beta stimulus","Annotated":225,"Significant":10,"Expected":13.59,"Rank in p.value_classic":4377,"p.value_elim":0.87764,"p.value_classic":0.8795,"genes":"APPL2,CDH5,CX3CR1,DAB2,EDN1,HTRA1,ITGB5,ONECUT2,PML,PXN"} {"GO.ID":"GO:0044380","Term":"protein localization to cytoskeleton","Annotated":59,"Significant":2,"Expected":3.56,"Rank in p.value_classic":4375,"p.value_elim":0.87823,"p.value_classic":0.87914,"genes":"SNX10,TRIM69"} {"GO.ID":"GO:0031113","Term":"regulation of microtubule polymerization","Annotated":59,"Significant":2,"Expected":3.56,"Rank in p.value_classic":4376,"p.value_elim":0.87823,"p.value_classic":0.87914,"genes":"CDH5,STMN1"} {"GO.ID":"GO:1903321","Term":"negative regulation of protein modification by small protein conjugation or removal","Annotated":82,"Significant":3,"Expected":4.95,"Rank in p.value_classic":4378,"p.value_elim":0.87882,"p.value_classic":0.8799,"genes":"DTX3L,MAD2L1,PARP10"} {"GO.ID":"GO:0010906","Term":"regulation of glucose metabolic process","Annotated":82,"Significant":3,"Expected":4.95,"Rank in p.value_classic":4379,"p.value_elim":0.87882,"p.value_classic":0.8799,"genes":"PDK4,PMAIP1,SLC45A3"} {"GO.ID":"GO:0006997","Term":"nucleus organization","Annotated":125,"Significant":5,"Expected":7.55,"Rank in p.value_classic":4388,"p.value_elim":0.87909,"p.value_classic":0.88044,"genes":"CDK1,CHMP4C,GOLM1,PML,SYNE1"} {"GO.ID":"GO:0016052","Term":"carbohydrate catabolic process","Annotated":125,"Significant":5,"Expected":7.55,"Rank in p.value_classic":4389,"p.value_elim":0.87909,"p.value_classic":0.88044,"genes":"G6PC1,GK,LRP5,P2RX7,SLC2A6"} {"GO.ID":"GO:0007041","Term":"lysosomal transport","Annotated":125,"Significant":5,"Expected":7.55,"Rank in p.value_classic":4390,"p.value_elim":0.87909,"p.value_classic":0.88044,"genes":"ATP13A2,CHMP4C,DTX3L,IGF2R,LRRK2"} {"GO.ID":"GO:0009409","Term":"response to cold","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4380,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"APPL2"} {"GO.ID":"GO:0001941","Term":"postsynaptic membrane organization","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4381,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"COLQ"} {"GO.ID":"GO:1990000","Term":"amyloid fibril formation","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4382,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"B2M"} {"GO.ID":"GO:0045324","Term":"late endosome to vacuole transport","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4383,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"CHMP4C"} {"GO.ID":"GO:1902110","Term":"positive regulation of mitochondrial membrane permeability involved in apoptotic process","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4384,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"BCL2L11"} {"GO.ID":"GO:0099054","Term":"presynapse assembly","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4385,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"MDGA1"} {"GO.ID":"GO:0046825","Term":"regulation of protein export from nucleus","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4386,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"IFI27"} {"GO.ID":"GO:1905332","Term":"positive regulation of morphogenesis of an epithelium","Annotated":34,"Significant":1,"Expected":2.05,"Rank in p.value_classic":4387,"p.value_elim":0.8794,"p.value_classic":0.88007,"genes":"AGT"} {"GO.ID":"GO:0009653","Term":"anatomical structure morphogenesis","Annotated":2114,"Significant":125,"Expected":127.68,"Rank in p.value_classic":3398,"p.value_elim":0.8801,"p.value_classic":0.62084,"genes":"ADAM8,ADAMTS15,AGR2,AGT,AMOT,ANK2,ANKH,ASB2,ATP8B1,BCL2L11,BCL6,BRCA1,C3,CCL13,CCL7,CD40,CDH5,CEACAM1,CELSR1,CIBAR1,COMP,CSF1,CTNS,CX3CR1,CXCL10,CXCL9,CXCR3,CYSLTR1,DAB1,DHRS3,DLL1,DNAAF1,DTNBP1,E2F2,E2F8,EDA,EDN1,EGR2,ENPP2,EPAS1,EPHB3,ETV7,FAM20A,FGD5,FGL1,FMNL2,FSTL4,GCNT3,GHRL,GLUL,HBEGF,HESX1,HGF,HLA-G,IFT122,IL12A,IL1RN,IL7,ITGA7,ITGB5,KLF4,LAMB3,LRATD1,LRP5,LRRK2,LYVE1,MICAL2,MIR503,MMP9,MPZL2,MTSS1,MYOZ2,NPR1,NR4A3,NRCAM,NRN1,NRP1,NYAP2,ONECUT2,P2RX7,PDE3B,PID1,PIM1,PLCD3,PLXNA2,PML,POLB,PRKX,PROK2,PSMB10,RAPGEF2,RNF213,RXFP1,S1PR1,SAT1,SBNO2,SDC2,SEMA6B,SGPL1,SH3PXD2A,SIDT2,SNX10,SOBP,SOX17,SPTBN4,SSBP3,STAT1,STAT2,STMN1,SYNE1,SYT1,TAL1,TGM2,THBS2,TIFAB,TMEM119,TMEM176B,TNFAIP2,TNFSF13B,TYMP,VEGFC,WARS1,WEE1,XRCC2,ZC3H12A"} {"GO.ID":"GO:0034250","Term":"positive regulation of amide metabolic process","Annotated":146,"Significant":6,"Expected":8.82,"Rank in p.value_classic":4391,"p.value_elim":0.88041,"p.value_classic":0.88187,"genes":"CCL5,CD28,DAZL,GSAP,NOD2,SAMD4A"} {"GO.ID":"GO:0006109","Term":"regulation of carbohydrate metabolic process","Annotated":146,"Significant":6,"Expected":8.82,"Rank in p.value_classic":4392,"p.value_elim":0.88041,"p.value_classic":0.88187,"genes":"P2RX7,PDK4,PLEK,PMAIP1,SLC2A6,SLC45A3"} {"GO.ID":"GO:0015908","Term":"fatty acid transport","Annotated":71,"Significant":6,"Expected":4.29,"Rank in p.value_classic":2084,"p.value_elim":0.88258,"p.value_classic":0.25721,"genes":"ACSL1,EDN1,P2RX4,P2RX7,RBP7,TNFRSF11A"} {"GO.ID":"GO:0065003","Term":"protein-containing complex assembly","Annotated":1377,"Significant":90,"Expected":83.16,"Rank in p.value_classic":1940,"p.value_elim":0.88273,"p.value_classic":0.22257,"genes":"AIM2,ANLN,APPL2,ASB2,ASIC1,B2M,BAZ1A,BCL2L11,CASP4,CD40,CD74,CDC45,CDH5,CDK1,CDT1,CENPF,CENPK,CHAF1B,COMP,CYLD,DAB2,DMC1,DNAAF1,DNM1,ERC2,FAM107A,FAS,FSCN1,GBP1,GBP2,GBP5,GCH1,GSDMD,H2BC21,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,IFIH1,JAK2,KCNJ2,KCTD14,LRRC61,LRRK2,MCM2,MEFV,MSRB1,OIP5,P2RX7,PLEK,PML,POMP,PRRT2,PSTPIP2,PTGER4,PXN,RALB,REPS2,RIPK2,RRM2,SCIN,SCO2,SOAT1,SPTBN4,SSBP3,STEAP4,STMN1,STX1A,SYT1,TAL1,TAPBP,TAPBPL,TIFA,TK1,TMSB10,TRABD2A,TRIM31,WARS1,ZC3H12A"} {"GO.ID":"GO:0050773","Term":"regulation of dendrite development","Annotated":83,"Significant":3,"Expected":5.01,"Rank in p.value_classic":4393,"p.value_elim":0.88386,"p.value_classic":0.88491,"genes":"RAPGEF2,SDC2,SYNE1"} {"GO.ID":"GO:0106027","Term":"neuron projection organization","Annotated":83,"Significant":3,"Expected":5.01,"Rank in p.value_classic":4394,"p.value_elim":0.88386,"p.value_classic":0.88491,"genes":"DTNBP1,EPHB3,LRRK2"} {"GO.ID":"GO:0050906","Term":"detection of stimulus involved in sensory perception","Annotated":83,"Significant":3,"Expected":5.01,"Rank in p.value_classic":4395,"p.value_elim":0.88386,"p.value_classic":0.88491,"genes":"OR2I1P,PKD1L3,RTP4"} {"GO.ID":"GO:2000628","Term":"regulation of miRNA metabolic process","Annotated":83,"Significant":3,"Expected":5.01,"Rank in p.value_classic":4396,"p.value_elim":0.88386,"p.value_classic":0.88491,"genes":"AGT,KLF4,ZC3H12A"} {"GO.ID":"GO:0008654","Term":"phospholipid biosynthetic process","Annotated":227,"Significant":10,"Expected":13.71,"Rank in p.value_classic":4411,"p.value_elim":0.88402,"p.value_classic":0.88582,"genes":"CDS1,CISH,LCLAT1,PCYT1A,PLAAT3,PLSCR1,PNPLA3,SERINC5,SOCS1,TMEM150A"} {"GO.ID":"GO:0060411","Term":"cardiac septum morphogenesis","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4397,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"DHRS3,NRP1"} {"GO.ID":"GO:0120193","Term":"tight junction organization","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4398,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"CDH5,MARVELD2"} {"GO.ID":"GO:0005977","Term":"glycogen metabolic process","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4399,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"G6PC1,PCDH12"} {"GO.ID":"GO:0010633","Term":"negative regulation of epithelial cell migration","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4400,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"KLF4,MIR503"} {"GO.ID":"GO:0090559","Term":"regulation of membrane permeability","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4401,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"BCL2L11,PMAIP1"} {"GO.ID":"GO:0048332","Term":"mesoderm morphogenesis","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4402,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"KLF4,TAL1"} {"GO.ID":"GO:0055002","Term":"striated muscle cell development","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4403,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"EDN1,MYOZ2"} {"GO.ID":"GO:0032835","Term":"glomerulus development","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4404,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"EDN1,MTSS1"} {"GO.ID":"GO:0061512","Term":"protein localization to cilium","Annotated":60,"Significant":2,"Expected":3.62,"Rank in p.value_classic":4405,"p.value_elim":0.88406,"p.value_classic":0.88494,"genes":"IFT122,SNX10"} {"GO.ID":"GO:0034032","Term":"purine nucleoside bisphosphate metabolic process","Annotated":105,"Significant":4,"Expected":6.34,"Rank in p.value_classic":4406,"p.value_elim":0.88422,"p.value_classic":0.88542,"genes":"ACOT4,ACSL1,DGAT2,PDK4"} {"GO.ID":"GO:0033865","Term":"nucleoside bisphosphate metabolic process","Annotated":105,"Significant":4,"Expected":6.34,"Rank in p.value_classic":4407,"p.value_elim":0.88422,"p.value_classic":0.88542,"genes":"ACOT4,ACSL1,DGAT2,PDK4"} {"GO.ID":"GO:0033875","Term":"ribonucleoside bisphosphate metabolic process","Annotated":105,"Significant":4,"Expected":6.34,"Rank in p.value_classic":4408,"p.value_elim":0.88422,"p.value_classic":0.88542,"genes":"ACOT4,ACSL1,DGAT2,PDK4"} {"GO.ID":"GO:0008286","Term":"insulin receptor signaling pathway","Annotated":105,"Significant":4,"Expected":6.34,"Rank in p.value_classic":4409,"p.value_elim":0.88422,"p.value_classic":0.88542,"genes":"PDK4,PID1,SESN3,SOCS1"} {"GO.ID":"GO:0044272","Term":"sulfur compound biosynthetic process","Annotated":147,"Significant":6,"Expected":8.88,"Rank in p.value_classic":4410,"p.value_elim":0.88427,"p.value_classic":0.8857,"genes":"ACSL1,CHAC1,DSE,GGT5,PDK4,XYLT1"} {"GO.ID":"GO:0090287","Term":"regulation of cellular response to growth factor stimulus","Annotated":266,"Significant":12,"Expected":16.07,"Rank in p.value_classic":4412,"p.value_elim":0.88428,"p.value_classic":0.88624,"genes":"AGT,CDH5,CHRD,DLL1,FSTL4,HTRA1,IL12A,MIR503,NRP1,ONECUT2,TNFAIP6,VEGFC"} {"GO.ID":"GO:0045576","Term":"mast cell activation","Annotated":52,"Significant":6,"Expected":3.14,"Rank in p.value_classic":1357,"p.value_elim":0.8854,"p.value_classic":0.0919,"genes":"CD300LF,HAVCR1,LYN,NR4A3,PLSCR1,S100A13"} {"GO.ID":"GO:0060560","Term":"developmental growth involved in morphogenesis","Annotated":208,"Significant":9,"Expected":12.56,"Rank in p.value_classic":4422,"p.value_elim":0.88624,"p.value_classic":0.88794,"genes":"CSF1,EDN1,FSTL4,NRCAM,NRN1,NRP1,S1PR1,SEMA6B,SYT1"} {"GO.ID":"GO:0007611","Term":"learning or memory","Annotated":208,"Significant":9,"Expected":12.56,"Rank in p.value_classic":4423,"p.value_elim":0.88624,"p.value_classic":0.88794,"genes":"ASIC1,B2M,CRHBP,CTNS,CX3CR1,EGR2,FEN1,RASGRF1,TIFAB"} {"GO.ID":"GO:1901605","Term":"alpha-amino acid metabolic process","Annotated":168,"Significant":7,"Expected":10.15,"Rank in p.value_classic":4421,"p.value_elim":0.88643,"p.value_classic":0.88794,"genes":"DHFR,GLUL,IDO1,IDO2,IL4I1,OCA2,SERINC5"} {"GO.ID":"GO:0030336","Term":"negative regulation of cell migration","Annotated":247,"Significant":15,"Expected":14.92,"Rank in p.value_classic":2994,"p.value_elim":0.88667,"p.value_classic":0.52972,"genes":"ADORA3,ATP1B2,CD74,CHRD,CX3CR1,IFITM1,KLF4,KLRK1,MIR503,PADI2,PTGER4,PTPRU,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0050885","Term":"neuromuscular process controlling balance","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4413,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"TIFAB"} {"GO.ID":"GO:0070884","Term":"regulation of calcineurin-NFAT signaling cascade","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4414,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"MYOZ2"} {"GO.ID":"GO:0043162","Term":"ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4415,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"CHMP4C"} {"GO.ID":"GO:1902003","Term":"regulation of amyloid-beta formation","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4416,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"GSAP"} {"GO.ID":"GO:1905953","Term":"negative regulation of lipid localization","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4417,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"TTC39B"} {"GO.ID":"GO:0046365","Term":"monosaccharide catabolic process","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4418,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"LRP5"} {"GO.ID":"GO:0042596","Term":"fear response","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4419,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"ASIC1"} {"GO.ID":"GO:0045815","Term":"transcription initiation-coupled chromatin remodeling","Annotated":35,"Significant":1,"Expected":2.11,"Rank in p.value_classic":4420,"p.value_elim":0.88669,"p.value_classic":0.88733,"genes":"PADI2"} {"GO.ID":"GO:0030177","Term":"positive regulation of Wnt signaling pathway","Annotated":127,"Significant":5,"Expected":7.67,"Rank in p.value_classic":4424,"p.value_elim":0.88731,"p.value_classic":0.8886,"genes":"AMER1,DAB2,DKK2,EDA,LRRK2"} {"GO.ID":"GO:0046661","Term":"male sex differentiation","Annotated":127,"Significant":5,"Expected":7.67,"Rank in p.value_classic":4425,"p.value_elim":0.88731,"p.value_classic":0.8886,"genes":"BCL2L11,KITLG,RHOBTB3,SGPL1,TNFSF10"} {"GO.ID":"GO:0051179","Term":"localization","Annotated":4257,"Significant":275,"Expected":257.1,"Rank in p.value_classic":1324,"p.value_elim":0.88783,"p.value_classic":0.08706,"genes":"ABCB1,ABCC11,ABCG2,ABLIM3,ACSL1,ADAM8,ADORA3,AGR2,AGT,AMOT,ANK2,ANKH,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARL4C,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BCL2A1,BCL2L11,BCL6,BIRC5,BRCA1,BUB1B,C1QTNF5,C2,C3,C4A,C4B,CACNA2D3,CADPS2,CALHM6,CAMK2D,CCL5,CCL8,CCNE2,CD163,CD300LF,CD38,CD74,CD93,CDCA5,CDH5,CDK1,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CHMP4C,CLEC10A,CLEC9A,CLIC5,COLEC12,COLQ,COMP,CRHBP,CTNS,CTSL,CTSS,CXADR,CXCL10,CXCL11,CXCL9,CYLD,CYSLTR1,DAB1,DAB2,DERL3,DGAT2,DLL1,DNAAF1,DNM1,DOP1A,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EEPD1,EGR2,EML4,ENPP2,ERC2,ESCO2,EXOC3L1,EXOC3L4,F2RL3,FCN1,FLVCR2,FYB1,G6PC1,GABRA3,GBP1,GBP2,GBP5,GCNT3,GHRL,GJD3,GLUL,GRAMD1B,GRIN3A,GSDMA,GSDMD,HAVCR1,HCAR2,HLA-DRB1,HLA-F,HRH2,IFI27,IFT122,IGF2R,IL12A,IL15,IL15RA,IL1RN,ITSN1,JAK2,KCNE5,KCNJ10,KCNJ15,KCNJ2,KPNA5,LAMP3,LAMP5,LGALS3BP,LILRA2,LIMK2,LMTK2,LPL,LRP5,LRRK2,LY75,LYN,LYVE1,MAD2L1,MAP1LC3C,MCOLN2,MCTP2,MERTK,MMD,MMP9,MUC1,MVP,MYO7B,MYOF,NCF1,NDC80,NECAB2,NOD2,NPR1,NR4A3,NRCAM,NRP1,NUF2,NUSAP1,OAS2,OCA2,OPTN,OSBPL6,OSM,P2RX4,P2RX7,PARP3,PARP9,PDE4B,PID1,PIM1,PKD1L3,PLAAT3,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PRRT2,PTPRU,PYHIN1,RAB20,RALB,RAPGEF2,RBP7,REEP1,REPS2,RHOBTB3,RNF213,RSAD2,RTP4,S100A10,S100A13,SCARF1,SCG3,SCIN,SCN4B,SEPTIN4,SERINC5,SIDT1,SIDT2,SLAMF1,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SNX10,SNX20,SOAT1,SPC24,SPC25,SPTBN4,SRI,STAP1,STEAP4,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAP1,TAP2,TAPBP,TESC,TGM2,TICAM2,TIFAB,TMEM109,TMEM144,TMEM150A,TMSB10,TNFAIP2,TNFAIP6,TNFAIP8L3,TNFRSF11A,TONSL,TPCN1,TRDN,TRIM17,TRIM22,TRIM69,TSPAN15,TTC39B,TYRO3,USP6NL,VAMP5,VEGFC,VPS9D1,WWP1,XKR6,ZC3H12A,ZDHHC19,ZWINT"} {"GO.ID":"GO:0001837","Term":"epithelial to mesenchymal transition","Annotated":148,"Significant":6,"Expected":8.94,"Rank in p.value_classic":4426,"p.value_elim":0.88802,"p.value_classic":0.88942,"genes":"ADAM8,AGT,DAB2,EDN1,GLIPR2,HGF"} {"GO.ID":"GO:1990778","Term":"protein localization to cell periphery","Annotated":306,"Significant":14,"Expected":18.48,"Rank in p.value_classic":4434,"p.value_elim":0.88852,"p.value_classic":0.89057,"genes":"AGR2,ANK2,DAB2,FYB1,GBP1,OPTN,PID1,RAPGEF2,S100A10,SPTBN4,TESC,TMEM150A,TSPAN15,VAMP5"} {"GO.ID":"GO:0046822","Term":"regulation of nucleocytoplasmic transport","Annotated":106,"Significant":4,"Expected":6.4,"Rank in p.value_classic":4428,"p.value_elim":0.88858,"p.value_classic":0.88975,"genes":"CDK1,IFI27,JAK2,ZC3H12A"} {"GO.ID":"GO:0090316","Term":"positive regulation of intracellular protein transport","Annotated":84,"Significant":3,"Expected":5.07,"Rank in p.value_classic":4427,"p.value_elim":0.8887,"p.value_classic":0.88973,"genes":"CDK1,JAK2,ZC3H12A"} {"GO.ID":"GO:0006611","Term":"protein export from nucleus","Annotated":61,"Significant":2,"Expected":3.68,"Rank in p.value_classic":4429,"p.value_elim":0.88963,"p.value_classic":0.89048,"genes":"EGR2,IFI27"} {"GO.ID":"GO:0030199","Term":"collagen fibril organization","Annotated":61,"Significant":2,"Expected":3.68,"Rank in p.value_classic":4430,"p.value_elim":0.88963,"p.value_classic":0.89048,"genes":"COLGALT2,COMP"} {"GO.ID":"GO:0061951","Term":"establishment of protein localization to plasma membrane","Annotated":61,"Significant":2,"Expected":3.68,"Rank in p.value_classic":4431,"p.value_elim":0.88963,"p.value_classic":0.89048,"genes":"OPTN,VAMP5"} {"GO.ID":"GO:0006919","Term":"activation of cysteine-type endopeptidase activity involved in apoptotic process","Annotated":61,"Significant":2,"Expected":3.68,"Rank in p.value_classic":4432,"p.value_elim":0.88963,"p.value_classic":0.89048,"genes":"JAK2,NLRP12"} {"GO.ID":"GO:1905515","Term":"non-motile cilium assembly","Annotated":61,"Significant":2,"Expected":3.68,"Rank in p.value_classic":4433,"p.value_elim":0.88963,"p.value_classic":0.89048,"genes":"IFT122,KCNJ10"} {"GO.ID":"GO:0008544","Term":"epidermis development","Annotated":229,"Significant":10,"Expected":13.83,"Rank in p.value_classic":4435,"p.value_elim":0.89013,"p.value_classic":0.89187,"genes":"DLL1,EDA,HLA-DRB1,KLF4,LAMB3,MAFF,OVOL1,PLAAT4,SLC4A7,STMN1"} {"GO.ID":"GO:0048583","Term":"regulation of response to stimulus","Annotated":3280,"Significant":284,"Expected":198.1,"Rank in p.value_classic":76,"p.value_elim":0.89023,"p.value_classic":1.5e-12,"genes":"ABCB1,ACOD1,ADAM8,AGR2,AGT,AIFM2,AIM2,AKAP7,AMER1,AMOT,APOBEC3G,APOL3,APPL2,ASCL2,ATF3,AURKB,B2M,BANK1,BCL2L11,BCL2L14,BCL6,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CAMK2D,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CEACAM1,CFB,CFH,CHAC1,CHRD,CIBAR1,CISH,CLEC6A,COLEC12,CR1L,CRHBP,CSF1,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB1,DAB2,DDX60,DEPTOR,DHFR,DHRS3,DKK2,DLGAP3,DLL1,DTNBP1,DTX3L,DYNLT1,EDA,EDN1,ENPP4,F2RL3,FAM13A,FAS,FCN1,FGD5,FGL1,FGL2,FSTL4,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GBP7,GCH1,GHRL,GLIPR2,GPR183,GPR31,GRAMD4,GRIN3A,GSDMD,HBEGF,HELLS,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HTRA1,ICAM1,IDO1,IFI35,IFIH1,IFIT5,IFT122,IL12A,IL12RB1,IL15,IL1RN,IL22RA2,IL27,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,ITSN1,JAK2,JAK3,KARS1,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LBH,LILRA2,LITAF,LPL,LRRK2,LTA,LYN,MAD2L1,MCF2L,MEFV,MIR503,MMP9,MTUS1,MUC1,MVP,MYOZ2,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRK,NRP1,OAS3,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDCD1,PDE3B,PDE4B,PID1,PIM1,PLEK,PLPP4,PLSCR1,PMAIP1,PML,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RGS18,RIPK2,RMI2,RNF213,RSAD2,RTN4RL1,S100A13,S1PR1,SBNO2,SCARF1,SCIMP,SECTM1,SEMA6B,SEPTIN4,SERPING1,SESN3,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC20A1,SOCS1,SOX17,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SUCNR1,SYNE1,TAGAP,TANK,TAP2,TBX21,TGM2,THBD,TICAM2,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TRABD2A,TRAFD1,TRIM22,TRIM31,TSPAN15,TSPAN32,TYRO3,UBD,VEGFC,VRK2,WDR76,ZBP1,ZC3H12A,ZNFX1,ZWINT"} {"GO.ID":"GO:1902600","Term":"proton transmembrane transport","Annotated":128,"Significant":5,"Expected":7.73,"Rank in p.value_classic":4436,"p.value_elim":0.89124,"p.value_classic":0.8925,"genes":"ATP6V0D2,CTNS,SLC11A1,SLC18A1,TESC"} {"GO.ID":"GO:1990138","Term":"neuron projection extension","Annotated":149,"Significant":6,"Expected":9,"Rank in p.value_classic":4437,"p.value_elim":0.89167,"p.value_classic":0.89304,"genes":"EDN1,NRCAM,NRN1,NRP1,SEMA6B,SYT1"} {"GO.ID":"GO:0008347","Term":"glial cell migration","Annotated":56,"Significant":7,"Expected":3.38,"Rank in p.value_classic":1119,"p.value_elim":0.89202,"p.value_classic":0.05048,"genes":"ATP1B2,CSF1,CX3CR1,DAB1,GPR183,P2RX4,STAP1"} {"GO.ID":"GO:0048518","Term":"positive regulation of biological process","Annotated":5040,"Significant":384,"Expected":304.39,"Rank in p.value_classic":133,"p.value_elim":0.89214,"p.value_classic":1.9e-09,"genes":"ABCB1,ABLIM3,ACOD1,ACSL1,ADAM8,AGR2,AGT,AIFM2,AIM2,AMER1,AMOT,ANK2,ANLN,APOL3,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP1B2,AURKB,B2M,BACH1,BANK1,BAZ1A,BCL2A1,BCL2L11,BCL6,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C21orf91,C3,C3orf38,C4A,C4B,CADPS2,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC6,CDCA5,CDH5,CDK1,CDS1,CDT1,CEACAM1,CFB,CFH,CHRD,CHTF18,CIBAR1,CIITA,CLEC6A,CLEC9A,CLSPN,COLEC12,COMP,CR1L,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DDX60,DEPTOR,DKK2,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,ENPP2,ENPP4,EPAS1,EPHB3,ERC2,F2RL3,FAM107A,FAM20A,FAS,FAXDC2,FCN1,FEN1,FLT3LG,FSCN1,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP3,GBP5,GBP7,GCH1,GHRL,GLIPR2,GPR183,GPR31,GRAMD4,GSAP,GSDMD,GTPBP1,HAPLN3,HAVCR1,HBEGF,HCAR2,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HRH2,HTRA1,ICAM1,IDO1,IFI35,IFIH1,IFIT2,IFIT5,IFITM1,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KCNE5,KCNJ2,KIF23,KITLG,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MARCKSL1,MCF2L,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MTSS1,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRK,NRP1,NUB1,NUSAP1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDCD1,PDCD1LG2,PDE4B,PID1,PIM1,PKIB,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,PPM1E,PRC1,PROK2,PRRT2,PSME1,PSME2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RELB,RIPK2,RRM2,RSAD2,RSU1,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCARF1,SCIMP,SCIN,SCN4B,SECTM1,SEMA6B,SEPTIN4,SERPING1,SESN3,SLAMF1,SLAMF6,SLC11A1,SLC20A1,SLC45A3,SOAT1,SOCS1,SOX17,SPTBN4,SRI,SSBP3,STAMBPL1,STAP1,STAT1,STAT2,STX1A,SUCNR1,SYNE1,SYNGR3,SYT1,TAL1,TANK,TAP2,TBX21,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TMEM119,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRDN,TRIM22,TRIM31,TYRO3,UBD,UHRF1,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,XRCC2,ZBP1,ZC3H12A,ZNF395,ZNFX1"} {"GO.ID":"GO:0060541","Term":"respiratory system development","Annotated":190,"Significant":8,"Expected":11.48,"Rank in p.value_classic":4439,"p.value_elim":0.89251,"p.value_classic":0.89405,"genes":"AGR2,CELSR1,DNAAF1,EDA,EPAS1,HESX1,HSD11B1,RXFP1"} {"GO.ID":"GO:0014706","Term":"striated muscle tissue development","Annotated":210,"Significant":9,"Expected":12.68,"Rank in p.value_classic":4440,"p.value_elim":0.89251,"p.value_classic":0.89414,"genes":"ASB2,CDK1,CENPF,CXADR,DLL1,EDN1,PIM1,S1PR1,SYNE1"} {"GO.ID":"GO:0000045","Term":"autophagosome assembly","Annotated":107,"Significant":4,"Expected":6.46,"Rank in p.value_classic":4438,"p.value_elim":0.8928,"p.value_classic":0.89394,"genes":"LRRK2,MAP1LC3C,RALB,RUFY4"} {"GO.ID":"GO:0044344","Term":"cellular response to fibroblast growth factor stimulus","Annotated":85,"Significant":3,"Expected":5.13,"Rank in p.value_classic":4457,"p.value_elim":0.89337,"p.value_classic":0.89437,"genes":"CCL5,MIR503,SHCBP1"} {"GO.ID":"GO:0021549","Term":"cerebellum development","Annotated":85,"Significant":3,"Expected":5.13,"Rank in p.value_classic":4458,"p.value_elim":0.89337,"p.value_classic":0.89437,"genes":"DAB1,DLL1,SSTR2"} {"GO.ID":"GO:0045663","Term":"positive regulation of myoblast differentiation","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4441,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"CXCL9"} {"GO.ID":"GO:0010799","Term":"regulation of peptidyl-threonine phosphorylation","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4442,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"RIPK2"} {"GO.ID":"GO:0010837","Term":"regulation of keratinocyte proliferation","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4443,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"OVOL1"} {"GO.ID":"GO:0010591","Term":"regulation of lamellipodium assembly","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4444,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"FSCN1"} {"GO.ID":"GO:0051084","Term":"'de novo' post-translational protein folding","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4445,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"CD74"} {"GO.ID":"GO:0050805","Term":"negative regulation of synaptic transmission","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4446,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"CD38"} {"GO.ID":"GO:0032205","Term":"negative regulation of telomere maintenance","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4447,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"XRN1"} {"GO.ID":"GO:0009948","Term":"anterior/posterior axis specification","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4448,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"TIFAB"} {"GO.ID":"GO:0106056","Term":"regulation of calcineurin-mediated signaling","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4449,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"MYOZ2"} {"GO.ID":"GO:2000780","Term":"negative regulation of double-strand break repair","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4450,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"RMI2"} {"GO.ID":"GO:0060999","Term":"positive regulation of dendritic spine development","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4451,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"C21orf91"} {"GO.ID":"GO:0050982","Term":"detection of mechanical stimulus","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4452,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"PKD1L3"} {"GO.ID":"GO:0043647","Term":"inositol phosphate metabolic process","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4453,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"PLEK"} {"GO.ID":"GO:0071711","Term":"basement membrane organization","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4454,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"CTSS"} {"GO.ID":"GO:0007595","Term":"lactation","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4455,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"OAS2"} {"GO.ID":"GO:1902686","Term":"mitochondrial outer membrane permeabilization involved in programmed cell death","Annotated":36,"Significant":1,"Expected":2.17,"Rank in p.value_classic":4456,"p.value_elim":0.89353,"p.value_classic":0.89415,"genes":"BCL2L11"} {"GO.ID":"GO:0018209","Term":"peptidyl-serine modification","Annotated":250,"Significant":11,"Expected":15.1,"Rank in p.value_classic":4463,"p.value_elim":0.8941,"p.value_classic":0.89587,"genes":"CAMK2D,CDK1,CLSPN,HGF,LMTK2,LRRK2,OSM,PRKX,RIPK2,SPTBN4,VRK2"} {"GO.ID":"GO:0051701","Term":"biological process involved in interaction with host","Annotated":166,"Significant":25,"Expected":10.03,"Rank in p.value_classic":310,"p.value_elim":0.89491,"p.value_classic":0.00002,"genes":"CD74,CD80,CDK1,CHMP4C,CIITA,CTSL,CXADR,DYNLT1,FCN1,HAVCR1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,ITGB5,NRP1,PLSCR1,SLAMF1,TNFRSF14,TPCN1,TRIM22,TRIM31,TYRO3,WWP1"} {"GO.ID":"GO:0044042","Term":"glucan metabolic process","Annotated":62,"Significant":2,"Expected":3.74,"Rank in p.value_classic":4459,"p.value_elim":0.89495,"p.value_classic":0.89578,"genes":"G6PC1,PCDH12"} {"GO.ID":"GO:1903051","Term":"negative regulation of proteolysis involved in protein catabolic process","Annotated":62,"Significant":2,"Expected":3.74,"Rank in p.value_classic":4460,"p.value_elim":0.89495,"p.value_classic":0.89578,"genes":"LAMP3,PML"} {"GO.ID":"GO:0008306","Term":"associative learning","Annotated":62,"Significant":2,"Expected":3.74,"Rank in p.value_classic":4461,"p.value_elim":0.89495,"p.value_classic":0.89578,"genes":"ASIC1,CTNS"} {"GO.ID":"GO:0008543","Term":"fibroblast growth factor receptor signaling pathway","Annotated":62,"Significant":2,"Expected":3.74,"Rank in p.value_classic":4462,"p.value_elim":0.89495,"p.value_classic":0.89578,"genes":"MIR503,SHCBP1"} {"GO.ID":"GO:0006694","Term":"steroid biosynthetic process","Annotated":129,"Significant":5,"Expected":7.79,"Rank in p.value_classic":4464,"p.value_elim":0.89505,"p.value_classic":0.89628,"genes":"CYP1A1,DAB2,FAXDC2,HSD3B7,OSBPL6"} {"GO.ID":"GO:1901292","Term":"nucleoside phosphate catabolic process","Annotated":150,"Significant":6,"Expected":9.06,"Rank in p.value_classic":4465,"p.value_elim":0.89522,"p.value_classic":0.89656,"genes":"DPYS,P2RX7,PDE4B,SLC2A6,TYMP,UNG"} {"GO.ID":"GO:0009205","Term":"purine ribonucleoside triphosphate metabolic process","Annotated":211,"Significant":9,"Expected":12.74,"Rank in p.value_classic":4466,"p.value_elim":0.89553,"p.value_classic":0.89713,"genes":"AK1,CTNS,GIMAP7,GTPBP1,LRRK2,P2RX7,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0046474","Term":"glycerophospholipid biosynthetic process","Annotated":191,"Significant":8,"Expected":11.54,"Rank in p.value_classic":4467,"p.value_elim":0.89567,"p.value_classic":0.89719,"genes":"CDS1,CISH,LCLAT1,PCYT1A,PLSCR1,PNPLA3,SOCS1,TMEM150A"} {"GO.ID":"GO:0051093","Term":"negative regulation of developmental process","Annotated":724,"Significant":52,"Expected":43.73,"Rank in p.value_classic":1434,"p.value_elim":0.89654,"p.value_classic":0.10791,"genes":"AMOT,APPL2,ASCL2,B2M,BCL6,BHLHE41,CD74,CEACAM1,CHRD,CTLA4,CXCL10,DAB1,DLL1,DTNBP1,DYNLT1,E2F1,E2F2,FGL2,FSTL4,GHRL,GRIN3A,HLA-G,IRF1,JAK3,KLF4,KREMEN1,LAG3,LBH,LILRB3,LRP5,LYN,MIR503,MMP9,NPR1,NRP1,PARP3,PDCD1,PDE3B,PML,RAPGEF2,RTN4RL1,SEMA6B,SOCS1,STAT1,TBX21,THBS2,TMEM119,TMEM176A,TMEM176B,TNFAIP6,VEGFC,ZC3H12A"} {"GO.ID":"GO:0044270","Term":"cellular nitrogen compound catabolic process","Annotated":498,"Significant":24,"Expected":30.08,"Rank in p.value_classic":4469,"p.value_elim":0.89719,"p.value_classic":0.89968,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,DAZL,DPYS,E2F1,ENPP4,FEN1,GTPBP1,IDO1,IDO2,IL4I1,ISG20,OAS2,P2RX7,PDE4B,SAMD4A,SIDT2,SLC11A1,SLC2A6,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:1901874","Term":"negative regulation of post-translational protein modification","Annotated":86,"Significant":3,"Expected":5.19,"Rank in p.value_classic":4468,"p.value_elim":0.89786,"p.value_classic":0.89883,"genes":"DTX3L,MAD2L1,PARP10"} {"GO.ID":"GO:0022411","Term":"cellular component disassembly","Annotated":480,"Significant":23,"Expected":28.99,"Rank in p.value_classic":4483,"p.value_elim":0.89837,"p.value_classic":0.9008,"genes":"ADAM8,ADAMTS15,ATP13A2,C1QB,C3,CALCOCO2,CDK1,CHMP4C,CTSS,CX3CR1,FSCN1,KIF18B,MAP1LC3C,MICAL2,MMP9,NOD2,OPTN,PLAAT3,PLEK,SCIN,SPTBN4,STMN1,TOP2A"} {"GO.ID":"GO:0006753","Term":"nucleoside phosphate metabolic process","Annotated":523,"Significant":29,"Expected":31.59,"Rank in p.value_classic":3786,"p.value_elim":0.89849,"p.value_classic":0.71267,"genes":"ACOT4,ACSL1,AK1,CD38,CMPK2,CTNS,DGAT2,DPYS,GIMAP7,GTPBP1,IDO1,IDO2,KARS1,LRRK2,NPR1,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,RRM2,SLC2A6,SLC4A7,TK1,TYMP,TYMS,UNG,VPS9D1"} {"GO.ID":"GO:0070507","Term":"regulation of microtubule cytoskeleton organization","Annotated":151,"Significant":6,"Expected":9.12,"Rank in p.value_classic":4470,"p.value_elim":0.89867,"p.value_classic":0.89998,"genes":"CDH5,CHMP4C,CYLD,FAM107A,PARP3,STMN1"} {"GO.ID":"GO:0071559","Term":"response to transforming growth factor beta","Annotated":232,"Significant":10,"Expected":14.01,"Rank in p.value_classic":4471,"p.value_elim":0.8988,"p.value_classic":0.90045,"genes":"APPL2,CDH5,CX3CR1,DAB2,EDN1,HTRA1,ITGB5,ONECUT2,PML,PXN"} {"GO.ID":"GO:0014002","Term":"astrocyte development","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4472,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"DLL1"} {"GO.ID":"GO:0009167","Term":"purine ribonucleoside monophosphate metabolic process","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4473,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"AK1"} {"GO.ID":"GO:0045687","Term":"positive regulation of glial cell differentiation","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4474,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"EGR2"} {"GO.ID":"GO:0060428","Term":"lung epithelium development","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4475,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"AGR2"} {"GO.ID":"GO:0042311","Term":"vasodilation","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4476,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"GCH1"} {"GO.ID":"GO:0051125","Term":"regulation of actin nucleation","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4477,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"SCIN"} {"GO.ID":"GO:0141137","Term":"positive regulation of gene expression, epigenetic","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4478,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"PADI2"} {"GO.ID":"GO:0035176","Term":"social behavior","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4479,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"CX3CR1"} {"GO.ID":"GO:0051703","Term":"biological process involved in intraspecies interaction between organisms","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4480,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"CX3CR1"} {"GO.ID":"GO:0032964","Term":"collagen biosynthetic process","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4481,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"CIITA"} {"GO.ID":"GO:0007632","Term":"visual behavior","Annotated":37,"Significant":1,"Expected":2.23,"Rank in p.value_classic":4482,"p.value_elim":0.89996,"p.value_classic":0.90056,"genes":"CTNS"} {"GO.ID":"GO:0045911","Term":"positive regulation of DNA recombination","Annotated":63,"Significant":2,"Expected":3.8,"Rank in p.value_classic":4484,"p.value_elim":0.90003,"p.value_classic":0.90083,"genes":"CD28,TBX21"} {"GO.ID":"GO:1903312","Term":"negative regulation of mRNA metabolic process","Annotated":87,"Significant":3,"Expected":5.25,"Rank in p.value_classic":4485,"p.value_elim":0.90218,"p.value_classic":0.90312,"genes":"DAZL,E2F1,SLC11A1"} {"GO.ID":"GO:0034644","Term":"cellular response to UV","Annotated":87,"Significant":3,"Expected":5.25,"Rank in p.value_classic":4486,"p.value_elim":0.90218,"p.value_classic":0.90312,"genes":"AURKB,CDC25A,MMP9"} {"GO.ID":"GO:0030307","Term":"positive regulation of cell growth","Annotated":131,"Significant":5,"Expected":7.91,"Rank in p.value_classic":4487,"p.value_elim":0.90232,"p.value_classic":0.9035,"genes":"CD38,EDN1,HBEGF,NRP1,SYT1"} {"GO.ID":"GO:0061061","Term":"muscle structure development","Annotated":557,"Significant":27,"Expected":33.64,"Rank in p.value_classic":4490,"p.value_elim":0.90365,"p.value_classic":0.90618,"genes":"ADAMTS15,ANK2,ASB2,ATF3,BHLHE41,CASP7,CDK1,CENPF,COMP,CXADR,CXCL10,CXCL9,DLL1,EDN1,EGR2,EPAS1,HBEGF,ITGA7,ITGB1BP2,MAFF,MYOZ2,S1PR1,SRI,SYNE1,TIFAB,TMEM119,VAMP5"} {"GO.ID":"GO:0072527","Term":"pyrimidine-containing compound metabolic process","Annotated":74,"Significant":10,"Expected":4.47,"Rank in p.value_classic":798,"p.value_elim":0.904,"p.value_classic":0.01312,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,CMPK2,DPYS,SLC4A7,TK1,TYMP,TYMS,UNG"} {"GO.ID":"GO:0061564","Term":"axon development","Annotated":408,"Significant":19,"Expected":24.64,"Rank in p.value_classic":4500,"p.value_elim":0.90457,"p.value_classic":0.90669,"genes":"DAB1,DHFR,EDN1,EGR2,EPHB3,FSTL4,JAK2,KLF4,KREMEN1,NRCAM,NRP1,OLIG1,PLXNA2,RTN4RL1,SCARF1,SEMA6B,SPTBN4,STMN1,TNFRSF21"} {"GO.ID":"GO:0046434","Term":"organophosphate catabolic process","Annotated":194,"Significant":8,"Expected":11.72,"Rank in p.value_classic":4489,"p.value_elim":0.90469,"p.value_classic":0.90612,"genes":"DPYS,ENPP2,P2RX7,PDE4B,PLB1,SLC2A6,TYMP,UNG"} {"GO.ID":"GO:1901880","Term":"negative regulation of protein depolymerization","Annotated":64,"Significant":2,"Expected":3.87,"Rank in p.value_classic":4488,"p.value_elim":0.90487,"p.value_classic":0.90566,"genes":"SCIN,SPTBN4"} {"GO.ID":"GO:0009101","Term":"glycoprotein biosynthetic process","Annotated":274,"Significant":12,"Expected":16.55,"Rank in p.value_classic":4501,"p.value_elim":0.90566,"p.value_classic":0.90736,"genes":"DERL3,DSE,GAL3ST4,GALNT18,GCNT3,HBEGF,IL15,JAK3,NECAB2,SOAT1,TMTC1,XYLT1"} {"GO.ID":"GO:0010762","Term":"regulation of fibroblast migration","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4491,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"APPL2"} {"GO.ID":"GO:0089718","Term":"amino acid import across plasma membrane","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4492,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"KCNJ10"} {"GO.ID":"GO:0032438","Term":"melanosome organization","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4493,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"DTNBP1"} {"GO.ID":"GO:0042168","Term":"heme metabolic process","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4494,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"ALAS1"} {"GO.ID":"GO:0042181","Term":"ketone biosynthetic process","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4495,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"DAB2"} {"GO.ID":"GO:0001895","Term":"retina homeostasis","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4496,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"ATP1B2"} {"GO.ID":"GO:0016266","Term":"O-glycan processing","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4497,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"GCNT3"} {"GO.ID":"GO:0035794","Term":"positive regulation of mitochondrial membrane permeability","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4498,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"BCL2L11"} {"GO.ID":"GO:0045738","Term":"negative regulation of DNA repair","Annotated":38,"Significant":1,"Expected":2.3,"Rank in p.value_classic":4499,"p.value_elim":0.90601,"p.value_classic":0.90659,"genes":"RMI2"} {"GO.ID":"GO:0010557","Term":"positive regulation of macromolecule biosynthetic process","Annotated":2129,"Significant":155,"Expected":128.58,"Rank in p.value_classic":675,"p.value_elim":0.90646,"p.value_classic":0.00576,"genes":"ABLIM3,ADAM8,AGR2,AGT,AIM2,ANK2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CHTF18,CIITA,CLEC6A,CLEC9A,CSF1,CXCL10,DAB2,DAZL,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,FCN1,GBP5,GCH1,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KLF4,KLRK1,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,MAF,MAFF,MAML3,MCOLN2,MEFV,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,P2RX7,PADI2,PARP9,PDE4B,PID1,PIM1,PKIB,PLSCR1,PTGER4,PYHIN1,RELB,RIPK2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF14,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WARS1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0031325","Term":"positive regulation of cellular metabolic process","Annotated":2757,"Significant":196,"Expected":166.51,"Rank in p.value_classic":662,"p.value_elim":0.90723,"p.value_classic":0.00512,"genes":"ABLIM3,ACOD1,ADAM8,AGR2,AGT,AIM2,ANK2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BANK1,BAZ1A,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CALCOCO2,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDH5,CDK1,CDT1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,CSF1,CTNS,CX3CR1,CXCL10,DAB2,DAZL,DEPTOR,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,FAM20A,FAS,FAXDC2,FCN1,GBP5,GCH1,GSDMD,GTPBP1,HBEGF,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MMD,MMP9,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NPM2,NR4A3,NRP1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDE4B,PID1,PIM1,PKIB,PLEK,PLSCR1,PML,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RIPK2,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SESN3,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRIM22,TRIM31,TYRO3,UHRF1,VEGFC,WARS1,WEE1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0007005","Term":"mitochondrion organization","Annotated":485,"Significant":23,"Expected":29.29,"Rank in p.value_classic":4505,"p.value_elim":0.90802,"p.value_classic":0.91028,"genes":"AIFM2,ATP13A2,BCL2A1,BCL2L11,CIBAR1,CXADR,EDN1,EPAS1,HGF,IFIT2,LRRK2,MAP1LC3C,MMP9,NOD2,OPTN,P2RX7,PID1,PMAIP1,PYROXD2,SCO2,STAT2,TNFSF10,TYMP"} {"GO.ID":"GO:0021782","Term":"glial cell development","Annotated":111,"Significant":4,"Expected":6.7,"Rank in p.value_classic":4502,"p.value_elim":0.9083,"p.value_classic":0.90933,"genes":"DLL1,KCNJ10,LYN,OLIG1"} {"GO.ID":"GO:0007178","Term":"transmembrane receptor protein serine/threonine kinase signaling pathway","Annotated":295,"Significant":13,"Expected":17.82,"Rank in p.value_classic":4506,"p.value_elim":0.90911,"p.value_classic":0.91083,"genes":"APPL2,CDH5,CHRD,COMP,DAB2,FSTL4,HTRA1,ITGB5,JAK2,ONECUT2,PML,PXN,TNFAIP6"} {"GO.ID":"GO:2000036","Term":"regulation of stem cell population maintenance","Annotated":65,"Significant":2,"Expected":3.93,"Rank in p.value_classic":4503,"p.value_elim":0.9095,"p.value_classic":0.91026,"genes":"LBH,TAL1"} {"GO.ID":"GO:0072078","Term":"nephron tubule morphogenesis","Annotated":65,"Significant":2,"Expected":3.93,"Rank in p.value_classic":4504,"p.value_elim":0.9095,"p.value_classic":0.91026,"genes":"AGT,CTNS"} {"GO.ID":"GO:0097435","Term":"supramolecular fiber organization","Annotated":708,"Significant":35,"Expected":42.76,"Rank in p.value_classic":4523,"p.value_elim":0.91025,"p.value_classic":0.91296,"genes":"B2M,CDH5,COLGALT2,COMP,EDN1,FAM107A,FSCN1,GHRL,INA,IQGAP3,ITGB5,JAK2,KIF18B,LIMK2,MARCKSL1,MICAL2,MSRB1,MTSS1,MYO7B,MYOZ2,NRP1,PLEK,PPM1E,PSTPIP2,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10,TNFAIP6,TRDN,XIRP1"} {"GO.ID":"GO:0090100","Term":"positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","Annotated":89,"Significant":3,"Expected":5.38,"Rank in p.value_classic":4507,"p.value_elim":0.91032,"p.value_classic":0.91122,"genes":"CDH5,DAB2,JAK2"} {"GO.ID":"GO:0019395","Term":"fatty acid oxidation","Annotated":89,"Significant":3,"Expected":5.38,"Rank in p.value_classic":4508,"p.value_elim":0.91032,"p.value_classic":0.91122,"genes":"APPL2,NR4A3,PDK4"} {"GO.ID":"GO:0048738","Term":"cardiac muscle tissue development","Annotated":196,"Significant":8,"Expected":11.84,"Rank in p.value_classic":4509,"p.value_elim":0.91033,"p.value_classic":0.9117,"genes":"ASB2,CDK1,CXADR,DLL1,EDN1,PIM1,S1PR1,SYNE1"} {"GO.ID":"GO:0051604","Term":"protein maturation","Annotated":449,"Significant":21,"Expected":27.12,"Rank in p.value_classic":4524,"p.value_elim":0.91093,"p.value_classic":0.91304,"genes":"ADAM8,B2M,C1R,C1RL,CARD16,CASP4,CASP7,CD74,CHAC1,COMP,CTSL,CTSS,ECEL1,LRRK2,P2RX7,RIPK2,S100A10,TAPBP,TESC,THBD,TSPAN15"} {"GO.ID":"GO:0071478","Term":"cellular response to radiation","Annotated":155,"Significant":6,"Expected":9.36,"Rank in p.value_classic":4520,"p.value_elim":0.91151,"p.value_classic":0.9127,"genes":"AURKB,BRCA1,CDC25A,MMP9,TANK,TMEM109"} {"GO.ID":"GO:0021543","Term":"pallium development","Annotated":155,"Significant":6,"Expected":9.36,"Rank in p.value_classic":4521,"p.value_elim":0.91151,"p.value_classic":0.9127,"genes":"DAB1,KIF26A,MDGA1,SEMA6B,TACC2,WDR62"} {"GO.ID":"GO:2001239","Term":"regulation of extrinsic apoptotic signaling pathway in absence of ligand","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4510,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"IL7"} {"GO.ID":"GO:0009126","Term":"purine nucleoside monophosphate metabolic process","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4511,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"AK1"} {"GO.ID":"GO:0099172","Term":"presynapse organization","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4512,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"MDGA1"} {"GO.ID":"GO:0051932","Term":"synaptic transmission, GABAergic","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4513,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"GABRA3"} {"GO.ID":"GO:0140718","Term":"facultative heterochromatin formation","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4514,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"HELLS"} {"GO.ID":"GO:0006305","Term":"DNA alkylation","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4515,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"HELLS"} {"GO.ID":"GO:0006306","Term":"DNA methylation","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4516,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"HELLS"} {"GO.ID":"GO:0048753","Term":"pigment granule organization","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4517,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"DTNBP1"} {"GO.ID":"GO:0032509","Term":"endosome transport via multivesicular body sorting pathway","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4518,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"CHMP4C"} {"GO.ID":"GO:1902108","Term":"regulation of mitochondrial membrane permeability involved in apoptotic process","Annotated":39,"Significant":1,"Expected":2.36,"Rank in p.value_classic":4519,"p.value_elim":0.91169,"p.value_classic":0.91224,"genes":"BCL2L11"} {"GO.ID":"GO:0042692","Term":"muscle cell differentiation","Annotated":335,"Significant":15,"Expected":20.23,"Rank in p.value_classic":4526,"p.value_elim":0.91172,"p.value_classic":0.91352,"genes":"ADAMTS15,ANK2,ASB2,BHLHE41,CASP7,CDK1,COMP,CXADR,CXCL10,CXCL9,DLL1,EDN1,MYOZ2,SYNE1,TMEM119"} {"GO.ID":"GO:0046165","Term":"alcohol biosynthetic process","Annotated":112,"Significant":4,"Expected":6.76,"Rank in p.value_classic":4522,"p.value_elim":0.91185,"p.value_classic":0.91285,"genes":"DAB2,DHFR,GCH1,PLEK"} {"GO.ID":"GO:0048705","Term":"skeletal system morphogenesis","Annotated":176,"Significant":7,"Expected":10.63,"Rank in p.value_classic":4525,"p.value_elim":0.91187,"p.value_classic":0.91314,"genes":"COMP,DHRS3,LRP5,P2RX7,SGPL1,TIFAB,TMEM119"} {"GO.ID":"GO:0009144","Term":"purine nucleoside triphosphate metabolic process","Annotated":217,"Significant":9,"Expected":13.11,"Rank in p.value_classic":4528,"p.value_elim":0.91221,"p.value_classic":0.91364,"genes":"AK1,CTNS,GIMAP7,GTPBP1,LRRK2,P2RX7,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0141091","Term":"transforming growth factor beta receptor superfamily signaling pathway","Annotated":277,"Significant":12,"Expected":16.73,"Rank in p.value_classic":4529,"p.value_elim":0.91278,"p.value_classic":0.91439,"genes":"APPL2,CDH5,CHRD,COMP,DAB2,FSTL4,HTRA1,ITGB5,ONECUT2,PML,PXN,TNFAIP6"} {"GO.ID":"GO:0002702","Term":"positive regulation of production of molecular mediator of immune response","Annotated":114,"Significant":18,"Expected":6.89,"Rank in p.value_classic":381,"p.value_elim":0.91355,"p.value_classic":0.00016,"genes":"B2M,CD28,CD74,HLA-A,HLA-E,HLA-F,HLA-G,NOD2,NR4A3,P2RX7,RIPK2,RSAD2,SCIMP,SLAMF1,TBX21,TICAM2,TLR7,TNFRSF14"} {"GO.ID":"GO:0006024","Term":"glycosaminoglycan biosynthetic process","Annotated":66,"Significant":2,"Expected":3.99,"Rank in p.value_classic":4531,"p.value_elim":0.91392,"p.value_classic":0.91466,"genes":"DSE,XYLT1"} {"GO.ID":"GO:2000146","Term":"negative regulation of cell motility","Annotated":257,"Significant":15,"Expected":15.52,"Rank in p.value_classic":3284,"p.value_elim":0.91396,"p.value_classic":0.59287,"genes":"ADORA3,ATP1B2,CD74,CHRD,CX3CR1,IFITM1,KLF4,KLRK1,MIR503,PADI2,PTGER4,PTPRU,SLAMF8,STAP1,TNFAIP6"} {"GO.ID":"GO:0071774","Term":"response to fibroblast growth factor","Annotated":90,"Significant":3,"Expected":5.44,"Rank in p.value_classic":4532,"p.value_elim":0.91416,"p.value_classic":0.91503,"genes":"CCL5,MIR503,SHCBP1"} {"GO.ID":"GO:0009199","Term":"ribonucleoside triphosphate metabolic process","Annotated":218,"Significant":9,"Expected":13.17,"Rank in p.value_classic":4533,"p.value_elim":0.91476,"p.value_classic":0.91616,"genes":"AK1,CTNS,GIMAP7,GTPBP1,LRRK2,P2RX7,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0050794","Term":"regulation of cellular process","Annotated":8403,"Significant":564,"Expected":507.5,"Rank in p.value_classic":278,"p.value_elim":0.91536,"p.value_classic":6.9e-06,"genes":"ABCB1,ABLIM3,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AKAP7,AMER1,AMOT,ANK2,ANLN,ANTXR1,APOBEC3A,APOBEC3D,APOBEC3G,APOL3,APPL2,ARAP2,ASB2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL2A1,BCL2L11,BCL2L14,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C2,C3,C3orf38,C4A,C4B,CADPS2,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CFH,CHAC1,CHMP4C,CHRD,CHTF18,CIBAR1,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,COLEC12,COLQ,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DAZL,DDX60,DEPDC7,DEPTOR,DERL3,DHFR,DHRS3,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DNAAF1,DNM1,DRAM1,DSCC1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EME1,ENPP2,EPAS1,EPHB3,EPOP,ERC2,ESCO2,ETV7,F2RL3,FAM107A,FAM13A,FAM20A,FAS,FAXDC2,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FSCN1,FSTL4,FYB1,G0S2,G6PC1,GADD45B,GAREM1,GBP1,GBP2,GBP3,GBP5,GBP7,GCH1,GFRA2,GHRL,GIMAP8,GLDN,GLIPR2,GLUL,GNG2,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GSDMD,GTPBP1,GTSE1,HAPLN3,HAVCR1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HIVEP2,HJURP,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSH2D,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JADE2,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ15,KCNJ2,KIF11,KIF18B,KIF23,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMP3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MARCKSL1,MCF2L,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MDGA1,MEFV,MERTK,MICAL2,MIR503,MKI67,MMD,MMP9,MRAS,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYOF,MYOZ2,NCAPG,NCAPG2,NCAPH,NCF1,NDC80,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRP1,NUCB1,NUF2,NUSAP1,NXPH2,NYAP2,OAS2,OAS3,OLFML2B,OLIG1,ONECUT2,OPTN,OR2I1P,ORC1,OSM,OVOL1,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PARP3,PARP9,PCDHGC3,PCLAF,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLAAT4,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLXNA2,PMAIP1,PML,POLB,PPM1E,PRC1,PRKX,PROK2,PRRT2,PSME1,PSME2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RIPK2,RMI2,RNF141,RNF213,RRM2,RSAD2,RSU1,RTN4RL1,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCARF1,SCIMP,SCIN,SCN4B,SDC2,SECTM1,SEMA6B,SEPTIN4,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC12A3,SLC20A1,SLC2A6,SLC31A2,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SPC24,SPC25,SPTBN4,SRI,SSBP3,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX1A,SUCNR1,SV2B,SYNE1,SYT1,SYT6,TAGAP,TAL1,TANK,TAP2,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM119,TMEM176A,TMEM176B,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRDN,TRIM17,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMP,TYMS,TYRO3,UBD,UHRF1,UNG,USP6NL,VCAM1,VCAN,VEGFC,VRK2,WARS1,WDR62,WDR76,WEE1,WWP1,XAF1,XRCC2,XRN1,ZBP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1,ZWINT"} {"GO.ID":"GO:0070848","Term":"response to growth factor","Annotated":601,"Significant":29,"Expected":36.3,"Rank in p.value_classic":4541,"p.value_elim":0.91544,"p.value_classic":0.91782,"genes":"AGT,APPL2,CCL5,CCNA2,CDH5,CHRD,COMP,CX3CR1,DAB2,DLL1,EDN1,FSTL4,GAREM1,HGF,HTRA1,IL12A,ITGB5,KLF4,MIR503,NRP1,ONECUT2,PML,PXN,RAPGEF2,SHCBP1,SLC4A7,TNFAIP6,VCAM1,VEGFC"} {"GO.ID":"GO:0048522","Term":"positive regulation of cellular process","Annotated":4652,"Significant":350,"Expected":280.96,"Rank in p.value_classic":181,"p.value_elim":0.91617,"p.value_classic":1.1e-07,"genes":"ABCB1,ABLIM3,ACOD1,ACSL1,ADAM8,AGR2,AGT,AIFM2,AIM2,AMER1,ANK2,ANLN,APOL3,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP1B2,AURKB,B2M,BACH1,BANK1,BAZ1A,BCL2A1,BCL2L11,BCL6,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,C2,C3,C3orf38,C4A,C4B,CADPS2,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC6,CDCA5,CDH5,CDK1,CDS1,CDT1,CEACAM1,CHRD,CHTF18,CIBAR1,CIITA,CLEC6A,CLEC9A,CLSPN,COMP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,CYP1A1,CYSLTR1,DAB1,DAB2,DAZL,DDX60,DEPTOR,DKK2,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPHB3,ERC2,F2RL3,FAM107A,FAM20A,FAS,FAXDC2,FCN1,FEN1,FLT3LG,FSCN1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP3,GBP5,GCH1,GHRL,GLIPR2,GPR183,GSDMD,GTPBP1,HAPLN3,HAVCR1,HBEGF,HCAR2,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HTRA1,ICAM1,IDO1,IFI35,IFIH1,IFIT2,IFIT5,IFITM1,IGF2R,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KCNE5,KCNJ2,KIF23,KITLG,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MARCKSL1,MCF2L,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MTSS1,MUC1,MYBL2,NCAPG,NCAPG2,NCAPH,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRK,NRP1,NUSAP1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP14,PARP3,PARP9,PDCD1,PDCD1LG2,PDE4B,PID1,PIM1,PKIB,PLAAT4,PLEK,PLSCR1,PLXNA2,PMAIP1,PML,PPM1E,PRC1,PRRT2,PTGER4,PTPRU,PXN,PYHIN1,RALB,RAPGEF2,RASGRF1,RELB,RIPK2,RRM2,RSAD2,RSU1,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCARF1,SCIMP,SCIN,SECTM1,SEMA6B,SEPTIN4,SESN3,SLAMF1,SLAMF6,SLC11A1,SLC20A1,SLC45A3,SOAT1,SOCS1,SOX17,SRI,SSBP3,STAMBPL1,STAP1,STAT1,STAT2,STX1A,SYNE1,SYT1,TAL1,TANK,TAP2,TBX21,TESC,TFEC,TGM2,THBS2,TICAM2,TIFA,TLR5,TLR7,TLR8,TMEM119,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRDN,TRIM22,TRIM31,TYRO3,UBD,UHRF1,VCAM1,VCAN,VEGFC,WARS1,WDR62,WEE1,XRCC2,ZBP1,ZC3H12A,ZNF395"} {"GO.ID":"GO:1905710","Term":"positive regulation of membrane permeability","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4534,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"BCL2L11"} {"GO.ID":"GO:0017004","Term":"cytochrome complex assembly","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4535,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"SCO2"} {"GO.ID":"GO:0033173","Term":"calcineurin-NFAT signaling cascade","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4536,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"MYOZ2"} {"GO.ID":"GO:0006458","Term":"'de novo' protein folding","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4537,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"CD74"} {"GO.ID":"GO:0045454","Term":"cell redox homeostasis","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4538,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"SLC11A1"} {"GO.ID":"GO:0001825","Term":"blastocyst formation","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4539,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"SOX17"} {"GO.ID":"GO:0046839","Term":"phospholipid dephosphorylation","Annotated":40,"Significant":1,"Expected":2.42,"Rank in p.value_classic":4540,"p.value_elim":0.91702,"p.value_classic":0.91756,"genes":"PLPP4"} {"GO.ID":"GO:0007029","Term":"endoplasmic reticulum organization","Annotated":91,"Significant":3,"Expected":5.5,"Rank in p.value_classic":4542,"p.value_elim":0.91785,"p.value_classic":0.91869,"genes":"LRRK2,REEP1,TRDN"} {"GO.ID":"GO:0021761","Term":"limbic system development","Annotated":91,"Significant":3,"Expected":5.5,"Rank in p.value_classic":4543,"p.value_elim":0.91785,"p.value_classic":0.91869,"genes":"DAB1,NRP1,SEMA6B"} {"GO.ID":"GO:0008333","Term":"endosome to lysosome transport","Annotated":67,"Significant":2,"Expected":4.05,"Rank in p.value_classic":4544,"p.value_elim":0.91814,"p.value_classic":0.91885,"genes":"CHMP4C,DTX3L"} {"GO.ID":"GO:0006303","Term":"double-strand break repair via nonhomologous end joining","Annotated":67,"Significant":2,"Expected":4.05,"Rank in p.value_classic":4545,"p.value_elim":0.91814,"p.value_classic":0.91885,"genes":"PARP3,POLB"} {"GO.ID":"GO:0070972","Term":"protein localization to endoplasmic reticulum","Annotated":67,"Significant":2,"Expected":4.05,"Rank in p.value_classic":4546,"p.value_elim":0.91814,"p.value_classic":0.91885,"genes":"ANK2,LRRK2"} {"GO.ID":"GO:0001649","Term":"osteoblast differentiation","Annotated":199,"Significant":8,"Expected":12.02,"Rank in p.value_classic":4548,"p.value_elim":0.91826,"p.value_classic":0.91955,"genes":"CHRD,HGF,IFITM1,LRP5,TMEM119,TNFAIP6,VCAN,VEGFC"} {"GO.ID":"GO:0043244","Term":"regulation of protein-containing complex disassembly","Annotated":114,"Significant":4,"Expected":6.89,"Rank in p.value_classic":4547,"p.value_elim":0.91858,"p.value_classic":0.91953,"genes":"CALCOCO2,PLEK,SCIN,SPTBN4"} {"GO.ID":"GO:0009266","Term":"response to temperature stimulus","Annotated":136,"Significant":5,"Expected":8.21,"Rank in p.value_classic":4549,"p.value_elim":0.91861,"p.value_classic":0.91965,"genes":"APPL2,CXCL10,HSBP1L1,LYN,TFEC"} {"GO.ID":"GO:0060341","Term":"regulation of cellular localization","Annotated":842,"Significant":42,"Expected":50.85,"Rank in p.value_classic":4553,"p.value_elim":0.91937,"p.value_classic":0.92212,"genes":"ABLIM3,ADAM8,AGR2,ATP13A2,CAMK2D,CCL5,CCNE2,CD38,CDK1,CYLD,DAB2,DERL3,DTX3L,EDN1,GBP1,GHRL,GLUL,HCAR2,HLA-DRB1,IFI27,IL12A,JAK2,LIMK2,LRP5,LRRK2,MMD,NECAB2,P2RX4,P2RX7,PARP9,PID1,PML,PYHIN1,RSAD2,SIDT2,SRI,STX1A,TNFAIP6,TRIM17,TRIM22,VEGFC,ZC3H12A"} {"GO.ID":"GO:0048562","Term":"embryonic organ morphogenesis","Annotated":220,"Significant":9,"Expected":13.29,"Rank in p.value_classic":4550,"p.value_elim":0.91967,"p.value_classic":0.92101,"genes":"ASB2,DLL1,DNAAF1,EDN1,HESX1,MICAL2,SOBP,SOX17,TIFAB"} {"GO.ID":"GO:0009117","Term":"nucleotide metabolic process","Annotated":516,"Significant":28,"Expected":31.16,"Rank in p.value_classic":3908,"p.value_elim":0.91976,"p.value_classic":0.75094,"genes":"ACOT4,ACSL1,AK1,CD38,CMPK2,CTNS,DGAT2,DPYS,GIMAP7,GTPBP1,IDO1,IDO2,KARS1,LRRK2,NPR1,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,RRM2,SLC2A6,SLC4A7,TYMP,TYMS,UNG,VPS9D1"} {"GO.ID":"GO:0140694","Term":"non-membrane-bounded organelle assembly","Annotated":370,"Significant":20,"Expected":22.35,"Rank in p.value_classic":3818,"p.value_elim":0.92002,"p.value_classic":0.72952,"genes":"ANLN,ASB2,AURKB,BIRC5,BRCA1,CDS1,CENPF,CENPK,CHMP4C,EDN1,FSCN1,KIF11,KIF23,MYBL2,MYOZ2,NDC80,PRC1,RNF213,UHRF1,WDR62"} {"GO.ID":"GO:0030258","Term":"lipid modification","Annotated":158,"Significant":6,"Expected":9.54,"Rank in p.value_classic":4551,"p.value_elim":0.92019,"p.value_classic":0.9213,"genes":"APPL2,CYP1A1,NR4A3,PDK4,PLPP4,RNF213"} {"GO.ID":"GO:0007034","Term":"vacuolar transport","Annotated":158,"Significant":6,"Expected":9.54,"Rank in p.value_classic":4552,"p.value_elim":0.92019,"p.value_classic":0.9213,"genes":"ATP13A2,ATP6V0D2,CHMP4C,DTX3L,IGF2R,LRRK2"} {"GO.ID":"GO:0022037","Term":"metencephalon development","Annotated":92,"Significant":3,"Expected":5.56,"Rank in p.value_classic":4554,"p.value_elim":0.92139,"p.value_classic":0.92221,"genes":"DAB1,DLL1,SSTR2"} {"GO.ID":"GO:0034440","Term":"lipid oxidation","Annotated":92,"Significant":3,"Expected":5.56,"Rank in p.value_classic":4555,"p.value_elim":0.92139,"p.value_classic":0.92221,"genes":"APPL2,NR4A3,PDK4"} {"GO.ID":"GO:0007044","Term":"cell-substrate junction assembly","Annotated":92,"Significant":3,"Expected":5.56,"Rank in p.value_classic":4556,"p.value_elim":0.92139,"p.value_classic":0.92221,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:0048640","Term":"negative regulation of developmental growth","Annotated":92,"Significant":3,"Expected":5.56,"Rank in p.value_classic":4557,"p.value_elim":0.92139,"p.value_classic":0.92221,"genes":"FSTL4,NRP1,SEMA6B"} {"GO.ID":"GO:0170039","Term":"proteinogenic amino acid metabolic process","Annotated":115,"Significant":4,"Expected":6.95,"Rank in p.value_classic":4563,"p.value_elim":0.92178,"p.value_classic":0.9227,"genes":"DHFR,GLUL,IL4I1,SERINC5"} {"GO.ID":"GO:0060828","Term":"regulation of canonical Wnt signaling pathway","Annotated":221,"Significant":9,"Expected":13.35,"Rank in p.value_classic":4566,"p.value_elim":0.92204,"p.value_classic":0.92335,"genes":"AMER1,CYLD,DAB2,DKK2,EDA,KREMEN1,LRRK2,PTPRU,SOX17"} {"GO.ID":"GO:0007033","Term":"vacuole organization","Annotated":221,"Significant":9,"Expected":13.35,"Rank in p.value_classic":4567,"p.value_elim":0.92204,"p.value_classic":0.92335,"genes":"ATP13A2,CHMP4C,LRRK2,MAP1LC3C,OCA2,P2RX7,RAB20,RALB,RUFY4"} {"GO.ID":"GO:0000184","Term":"nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","Annotated":41,"Significant":1,"Expected":2.48,"Rank in p.value_classic":4558,"p.value_elim":0.92204,"p.value_classic":0.92255,"genes":"ZC3H12A"} {"GO.ID":"GO:0030521","Term":"androgen receptor signaling pathway","Annotated":41,"Significant":1,"Expected":2.48,"Rank in p.value_classic":4559,"p.value_elim":0.92204,"p.value_classic":0.92255,"genes":"DAB2"} {"GO.ID":"GO:0050919","Term":"negative chemotaxis","Annotated":41,"Significant":1,"Expected":2.48,"Rank in p.value_classic":4560,"p.value_elim":0.92204,"p.value_classic":0.92255,"genes":"SEMA6B"} {"GO.ID":"GO:0060976","Term":"coronary vasculature development","Annotated":41,"Significant":1,"Expected":2.48,"Rank in p.value_classic":4561,"p.value_elim":0.92204,"p.value_classic":0.92255,"genes":"NRP1"} {"GO.ID":"GO:0035307","Term":"positive regulation of protein dephosphorylation","Annotated":41,"Significant":1,"Expected":2.48,"Rank in p.value_classic":4562,"p.value_elim":0.92204,"p.value_classic":0.92255,"genes":"CDH5"} {"GO.ID":"GO:0019218","Term":"regulation of steroid metabolic process","Annotated":68,"Significant":2,"Expected":4.11,"Rank in p.value_classic":4564,"p.value_elim":0.92216,"p.value_classic":0.92284,"genes":"DAB2,TTC39B"} {"GO.ID":"GO:0050772","Term":"positive regulation of axonogenesis","Annotated":68,"Significant":2,"Expected":4.11,"Rank in p.value_classic":4565,"p.value_elim":0.92216,"p.value_classic":0.92284,"genes":"NRP1,PLXNA2"} {"GO.ID":"GO:0065007","Term":"biological regulation","Annotated":9079,"Significant":612,"Expected":548.33,"Rank in p.value_classic":186,"p.value_elim":0.9239,"p.value_classic":1.3e-07,"genes":"ABCB1,ABLIM3,ACOD1,ACSL1,ADAM8,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AKAP7,AMER1,AMOT,ANK2,ANKH,ANLN,ANO4,ANTXR1,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL3,APPL2,ARAP2,ASB2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL2A1,BCL2L11,BCL2L14,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C1QB,C1R,C1RL,C1S,C2,C21orf91,C3,C3orf38,C4A,C4B,CADPS2,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CCRL2,CD101,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD7,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CFB,CFH,CHAC1,CHMP4C,CHRD,CHTF18,CIBAR1,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,COLEC12,COLQ,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DAZL,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DNAAF1,DNM1,DRAM1,DSCC1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPOP,ERAP2,ERC2,ESCO2,ETV7,EXOC3L1,F2RL3,FAM107A,FAM13A,FAM20A,FAS,FAXDC2,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FMNL2,FSCN1,FSTL4,FYB1,G0S2,G6PC1,GABRA3,GADD45B,GAL3ST4,GAREM1,GBP1,GBP2,GBP3,GBP5,GBP7,GCH1,GFRA2,GHRL,GIMAP8,GJD3,GLDN,GLIPR2,GLUL,GNG2,GOLM1,GPR183,GPR31,GRAMD4,GRIN3A,GRM8,GSAP,GSDMD,GTPBP1,GTSE1,HAPLN3,HAVCR1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HIVEP2,HJURP,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSH2D,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ISG20,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JADE2,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ15,KCNJ2,KIF11,KIF18B,KIF23,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LACTB,LAG3,LAMP3,LBH,LGALS3BP,LILRA1,LILRA2,LILRB3,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MARCKSL1,MCF2L,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MDGA1,MEFV,MERTK,MICAL2,MIR503,MKI67,MMD,MMP9,MRAS,MT2A,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYOF,MYOZ2,NCAPG,NCAPG2,NCAPH,NCF1,NDC80,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRP1,NUB1,NUCB1,NUF2,NUSAP1,NXPH2,NYAP2,OAS2,OAS3,OCA2,OLFML2B,OLIG1,ONECUT2,OPTN,OR2I1P,ORC1,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,P2RY14,PADI2,PAQR8,PARP10,PARP14,PARP3,PARP9,PCDHGC3,PCLAF,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,POLB,PPM1E,PRC1,PRKX,PROK2,PRRT2,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PTPRU,PXN,PYHIN1,RAB20,RALB,RAPGEF2,RASGEF1C,RASGRF1,RELB,REPS2,RGS18,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF213,RRM2,RSAD2,RSU1,RTN4RL1,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCARF1,SCIMP,SCIN,SCN4B,SDC2,SECTM1,SELENOP,SEMA6B,SEPTIN4,SERINC5,SERPING1,SESN3,SGPL1,SHCBP1,SIDT2,SIT1,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC12A3,SLC16A10,SLC20A1,SLC2A5,SLC2A6,SLC31A2,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPC24,SPC25,SPTBN4,SRI,SSBP3,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAGAP,TAL1,TANK,TAP2,TAPBP,TAPBPL,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TICRR,TIFA,TIFAB,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM119,TMEM176A,TMEM176B,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRAFD1,TRDN,TRIM17,TRIM22,TRIM31,TSPAN15,TSPAN32,TTC39B,TYMP,TYMS,TYRO3,UBD,UHRF1,UNG,USP53,USP6NL,VCAM1,VCAN,VEGFC,VRK2,WARS1,WDR62,WDR76,WEE1,WWP1,XAF1,XIRP1,XKR6,XRCC2,XRN1,ZBP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1,ZWINT"} {"GO.ID":"GO:0009179","Term":"purine ribonucleoside diphosphate metabolic process","Annotated":93,"Significant":3,"Expected":5.62,"Rank in p.value_classic":4568,"p.value_elim":0.92479,"p.value_classic":0.92559,"genes":"AK1,P2RX7,SLC2A6"} {"GO.ID":"GO:0009135","Term":"purine nucleoside diphosphate metabolic process","Annotated":93,"Significant":3,"Expected":5.62,"Rank in p.value_classic":4569,"p.value_elim":0.92479,"p.value_classic":0.92559,"genes":"AK1,P2RX7,SLC2A6"} {"GO.ID":"GO:0007032","Term":"endosome organization","Annotated":93,"Significant":3,"Expected":5.62,"Rank in p.value_classic":4570,"p.value_elim":0.92479,"p.value_classic":0.92559,"genes":"CHMP4C,DNM1,SNX10"} {"GO.ID":"GO:0003279","Term":"cardiac septum development","Annotated":93,"Significant":3,"Expected":5.62,"Rank in p.value_classic":4571,"p.value_elim":0.92479,"p.value_classic":0.92559,"genes":"ANK2,DHRS3,NRP1"} {"GO.ID":"GO:0048598","Term":"embryonic morphogenesis","Annotated":495,"Significant":23,"Expected":29.9,"Rank in p.value_classic":4576,"p.value_elim":0.92509,"p.value_classic":0.92704,"genes":"AMOT,ASB2,BCL2L11,CELSR1,DLL1,DNAAF1,EDN1,HESX1,IFT122,IL1RN,ITGA7,ITGB5,KLF4,LAMB3,LRP5,MICAL2,MMP9,NR4A3,SOBP,SOX17,TAL1,TIFAB,VEGFC"} {"GO.ID":"GO:0060485","Term":"mesenchyme development","Annotated":263,"Significant":11,"Expected":15.88,"Rank in p.value_classic":4575,"p.value_elim":0.92559,"p.value_classic":0.92698,"genes":"ADAM8,AGT,AMER1,DAB2,EDN1,GLIPR2,HGF,KITLG,NRP1,SEMA6B,STAT1"} {"GO.ID":"GO:0009798","Term":"axis specification","Annotated":69,"Significant":2,"Expected":4.17,"Rank in p.value_classic":4572,"p.value_elim":0.92599,"p.value_classic":0.92666,"genes":"DLL1,TIFAB"} {"GO.ID":"GO:0033138","Term":"positive regulation of peptidyl-serine phosphorylation","Annotated":69,"Significant":2,"Expected":4.17,"Rank in p.value_classic":4573,"p.value_elim":0.92599,"p.value_classic":0.92666,"genes":"OSM,RIPK2"} {"GO.ID":"GO:0006023","Term":"aminoglycan biosynthetic process","Annotated":69,"Significant":2,"Expected":4.17,"Rank in p.value_classic":4574,"p.value_elim":0.92599,"p.value_classic":0.92666,"genes":"DSE,XYLT1"} {"GO.ID":"GO:0031328","Term":"positive regulation of cellular biosynthetic process","Annotated":2187,"Significant":157,"Expected":132.08,"Rank in p.value_classic":739,"p.value_elim":0.92625,"p.value_classic":0.00915,"genes":"ABLIM3,ADAM8,AGR2,AGT,AIM2,ANK2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CHTF18,CIITA,CLEC6A,CLEC9A,CSF1,CXCL10,DAB2,DAZL,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,FCN1,GBP5,GCH1,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KLF4,KLRK1,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,MAF,MAFF,MAML3,MCOLN2,MEFV,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,P2RX4,P2RX7,PADI2,PARP9,PDE4B,PID1,PIM1,PKIB,PLSCR1,PTGER4,PYHIN1,RELB,RIPK2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF14,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WARS1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0006163","Term":"purine nucleotide metabolic process","Annotated":458,"Significant":21,"Expected":27.66,"Rank in p.value_classic":4583,"p.value_elim":0.92653,"p.value_classic":0.92837,"genes":"ACOT4,ACSL1,AK1,CD38,CTNS,DGAT2,GIMAP7,GTPBP1,IDO1,IDO2,LRRK2,NPR1,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,SLC2A6,SLC4A7,VPS9D1"} {"GO.ID":"GO:0015909","Term":"long-chain fatty acid transport","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4577,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"ACSL1"} {"GO.ID":"GO:0042446","Term":"hormone biosynthetic process","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4578,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"DAB2"} {"GO.ID":"GO:0018198","Term":"peptidyl-cysteine modification","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4579,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"ZDHHC19"} {"GO.ID":"GO:0045104","Term":"intermediate filament cytoskeleton organization","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4580,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"INA"} {"GO.ID":"GO:0097720","Term":"calcineurin-mediated signaling","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4581,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"MYOZ2"} {"GO.ID":"GO:1903573","Term":"negative regulation of response to endoplasmic reticulum stress","Annotated":42,"Significant":1,"Expected":2.54,"Rank in p.value_classic":4582,"p.value_elim":0.92675,"p.value_classic":0.92725,"genes":"LRRK2"} {"GO.ID":"GO:0007017","Term":"microtubule-based process","Annotated":770,"Significant":41,"Expected":46.5,"Rank in p.value_classic":4162,"p.value_elim":0.92712,"p.value_classic":0.82491,"genes":"ATF5,AURKB,BIRC5,BRCA1,CCDC170,CCNF,CDH5,CDK1,CHMP4C,CYLD,DNAAF1,DTNBP1,DYNLT1,DYNLT5,EML4,FAM107A,GTSE1,IFT122,KIF11,KIF15,KIF18B,KIF23,LIMK2,LRRC61,MAD2L1,MYBL2,NDC80,NUF2,NUSAP1,PARP3,PCLAF,PRC1,SEPTIN4,SPC25,STMN1,TACC2,TRDN,UHRF1,WDR62,WEE1,XRCC2"} {"GO.ID":"GO:0051147","Term":"regulation of muscle cell differentiation","Annotated":117,"Significant":4,"Expected":7.07,"Rank in p.value_classic":4584,"p.value_elim":0.92782,"p.value_classic":0.9287,"genes":"BHLHE41,DLL1,EDN1,TMEM119"} {"GO.ID":"GO:0006094","Term":"gluconeogenesis","Annotated":70,"Significant":2,"Expected":4.23,"Rank in p.value_classic":4585,"p.value_elim":0.92964,"p.value_classic":0.93029,"genes":"ATF3,G6PC1"} {"GO.ID":"GO:0001656","Term":"metanephros development","Annotated":70,"Significant":2,"Expected":4.23,"Rank in p.value_classic":4586,"p.value_elim":0.92964,"p.value_classic":0.93029,"genes":"SOX17,STAT1"} {"GO.ID":"GO:1902893","Term":"regulation of miRNA transcription","Annotated":70,"Significant":2,"Expected":4.23,"Rank in p.value_classic":4587,"p.value_elim":0.92964,"p.value_classic":0.93029,"genes":"AGT,KLF4"} {"GO.ID":"GO:0030182","Term":"neuron differentiation","Annotated":1122,"Significant":57,"Expected":67.76,"Rank in p.value_classic":4597,"p.value_elim":0.92994,"p.value_classic":0.93282,"genes":"ASCL2,ATF5,ATP1B2,ATP8B1,B2M,BCL6,C21orf91,C3,CASZ1,CD38,DAB1,DAB2,DHFR,DLL1,DTNBP1,EDN1,EGR2,EPHB3,EPOP,FSTL4,GHRL,GLDN,GRIN3A,IL15RA,JAK2,KIF26A,KLF4,KREMEN1,LRRK2,LYN,MDGA1,MMD,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,PCDH12,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S1PR1,SCARF1,SDC2,SEMA6B,SLC4A7,SPTBN4,STMN1,SYNE1,SYT1,TAL1,TNFRSF21,VCAM1,WDR62,WEE1"} {"GO.ID":"GO:0009100","Term":"glycoprotein metabolic process","Annotated":325,"Significant":14,"Expected":19.63,"Rank in p.value_classic":4595,"p.value_elim":0.93032,"p.value_classic":0.93179,"genes":"CTSL,DERL3,DSE,FBXO6,GAL3ST4,GALNT18,GCNT3,HBEGF,IL15,JAK3,NECAB2,SOAT1,TMTC1,XYLT1"} {"GO.ID":"GO:0170036","Term":"import into the mitochondrion","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4588,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"SLC25A28"} {"GO.ID":"GO:0032365","Term":"intracellular lipid transport","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4589,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"GRAMD1B"} {"GO.ID":"GO:0034205","Term":"amyloid-beta formation","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4590,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"GSAP"} {"GO.ID":"GO:0007007","Term":"inner mitochondrial membrane organization","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4591,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"CIBAR1"} {"GO.ID":"GO:0047496","Term":"vesicle transport along microtubule","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4592,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"DTNBP1"} {"GO.ID":"GO:0035329","Term":"hippo signaling","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4593,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"AMOT"} {"GO.ID":"GO:0043616","Term":"keratinocyte proliferation","Annotated":43,"Significant":1,"Expected":2.6,"Rank in p.value_classic":4594,"p.value_elim":0.93117,"p.value_classic":0.93165,"genes":"OVOL1"} {"GO.ID":"GO:1905477","Term":"positive regulation of protein localization to membrane","Annotated":95,"Significant":3,"Expected":5.74,"Rank in p.value_classic":4596,"p.value_elim":0.9312,"p.value_classic":0.93194,"genes":"AGR2,NECAB2,TNFAIP6"} {"GO.ID":"GO:1905475","Term":"regulation of protein localization to membrane","Annotated":163,"Significant":6,"Expected":9.84,"Rank in p.value_classic":4600,"p.value_elim":0.933,"p.value_classic":0.93399,"genes":"AGR2,DAB2,GBP1,NECAB2,PID1,TNFAIP6"} {"GO.ID":"GO:1903533","Term":"regulation of protein targeting","Annotated":71,"Significant":2,"Expected":4.29,"Rank in p.value_classic":4598,"p.value_elim":0.93313,"p.value_classic":0.93375,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0061614","Term":"miRNA transcription","Annotated":71,"Significant":2,"Expected":4.29,"Rank in p.value_classic":4599,"p.value_elim":0.93313,"p.value_classic":0.93375,"genes":"AGT,KLF4"} {"GO.ID":"GO:0061024","Term":"membrane organization","Annotated":712,"Significant":42,"Expected":43,"Rank in p.value_classic":3271,"p.value_elim":0.93322,"p.value_classic":0.58817,"genes":"ABCB1,ANK2,ANO4,APPL2,ATP13A2,ATP8B1,AURKB,BCL2L11,C3,CASP7,CHMP4C,CIBAR1,COLEC12,COLQ,CTSL,DNM1,ERC2,GLDN,GRAMD1B,HAVCR1,MTSS1,MYOF,NRCAM,P2RX7,PLAAT3,PLSCR1,PLSCR4,PMAIP1,PRRT2,RAB20,REEP1,RTP4,S100A10,SLAMF1,SPTBN4,STAP1,STX11,STX1A,SYT1,TNFAIP8L3,TRDN,XKR6"} {"GO.ID":"GO:0043161","Term":"proteasome-mediated ubiquitin-dependent protein catabolic process","Annotated":366,"Significant":16,"Expected":22.1,"Rank in p.value_classic":4603,"p.value_elim":0.93341,"p.value_classic":0.93492,"genes":"ASB2,CCNF,DAB2,DTL,FBXO6,FEM1C,IFI27,LRRK2,NUB1,PML,PSMB10,PSMB8,PSMB9,RHOBTB3,TBX21,WWP1"} {"GO.ID":"GO:1901565","Term":"organonitrogen compound catabolic process","Annotated":1251,"Significant":64,"Expected":75.55,"Rank in p.value_classic":4611,"p.value_elim":0.93344,"p.value_classic":0.93637,"genes":"ADAM8,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,ASB2,ATP13A2,CASP7,CCNF,CEACAM1,CHAC1,CHMP4C,CTRL,CTSL,CTSO,CTSS,DAB2,DERL3,DPYS,DTL,DTX3L,ENPP2,ENPP4,ERAP2,FBXO6,FEM1C,GGT5,GLUL,IDO1,IDO2,IFI27,IL4I1,LAMP3,LRRK2,LYVE1,MAD2L1,NUB1,P2RX7,PDE4B,PLB1,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RNF19B,RNF213,SAT1,SGPL1,SLC2A6,SOX17,TBX21,TRIM31,TSPAN15,TYMP,UBD,UBE2L6,UHRF1,UNG,WWP1"} {"GO.ID":"GO:0009261","Term":"ribonucleotide catabolic process","Annotated":119,"Significant":4,"Expected":7.19,"Rank in p.value_classic":4601,"p.value_elim":0.93345,"p.value_classic":0.93427,"genes":"DPYS,P2RX7,PDE4B,SLC2A6"} {"GO.ID":"GO:0007286","Term":"spermatid development","Annotated":119,"Significant":4,"Expected":7.19,"Rank in p.value_classic":4602,"p.value_elim":0.93345,"p.value_classic":0.93427,"genes":"ADGB,DMC1,OCA2,ZMYND15"} {"GO.ID":"GO:0006090","Term":"pyruvate metabolic process","Annotated":96,"Significant":3,"Expected":5.8,"Rank in p.value_classic":4604,"p.value_elim":0.93421,"p.value_classic":0.93493,"genes":"P2RX7,PDK4,SLC2A6"} {"GO.ID":"GO:1902115","Term":"regulation of organelle assembly","Annotated":206,"Significant":8,"Expected":12.44,"Rank in p.value_classic":4605,"p.value_elim":0.93445,"p.value_classic":0.93555,"genes":"BRCA1,CDKL1,CHMP4C,CYLD,FSCN1,LIMK2,LRRK2,RALB"} {"GO.ID":"GO:0048666","Term":"neuron development","Annotated":928,"Significant":46,"Expected":56.05,"Rank in p.value_classic":4614,"p.value_elim":0.93498,"p.value_classic":0.93743,"genes":"ATF5,ATP1B2,ATP8B1,B2M,C21orf91,C3,CD38,DAB1,DAB2,DHFR,DTNBP1,EDN1,EGR2,EPHB3,FSTL4,GHRL,GLDN,GRIN3A,IL15RA,JAK2,KIF26A,KLF4,KREMEN1,LRRK2,LYN,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,PCDH12,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,SCARF1,SDC2,SEMA6B,SLC4A7,SPTBN4,STMN1,SYNE1,SYT1,TNFRSF21,WEE1"} {"GO.ID":"GO:1990090","Term":"cellular response to nerve growth factor stimulus","Annotated":44,"Significant":1,"Expected":2.66,"Rank in p.value_classic":4606,"p.value_elim":0.93533,"p.value_classic":0.9358,"genes":"RAPGEF2"} {"GO.ID":"GO:1990089","Term":"response to nerve growth factor","Annotated":44,"Significant":1,"Expected":2.66,"Rank in p.value_classic":4607,"p.value_elim":0.93533,"p.value_classic":0.9358,"genes":"RAPGEF2"} {"GO.ID":"GO:0120163","Term":"negative regulation of cold-induced thermogenesis","Annotated":44,"Significant":1,"Expected":2.66,"Rank in p.value_classic":4608,"p.value_elim":0.93533,"p.value_classic":0.9358,"genes":"IL15"} {"GO.ID":"GO:0048009","Term":"insulin-like growth factor receptor signaling pathway","Annotated":44,"Significant":1,"Expected":2.66,"Rank in p.value_classic":4609,"p.value_elim":0.93533,"p.value_classic":0.9358,"genes":"IGF2R"} {"GO.ID":"GO:0021695","Term":"cerebellar cortex development","Annotated":44,"Significant":1,"Expected":2.66,"Rank in p.value_classic":4610,"p.value_elim":0.93533,"p.value_classic":0.9358,"genes":"DLL1"} {"GO.ID":"GO:0006661","Term":"phosphatidylinositol biosynthetic process","Annotated":120,"Significant":4,"Expected":7.25,"Rank in p.value_classic":4612,"p.value_elim":0.93611,"p.value_classic":0.93691,"genes":"CDS1,CISH,SOCS1,TMEM150A"} {"GO.ID":"GO:0060291","Term":"long-term synaptic potentiation","Annotated":72,"Significant":2,"Expected":4.35,"Rank in p.value_classic":4613,"p.value_elim":0.93645,"p.value_classic":0.93705,"genes":"CX3CR1,FAM107A"} {"GO.ID":"GO:0030031","Term":"cell projection assembly","Annotated":503,"Significant":23,"Expected":30.38,"Rank in p.value_classic":4616,"p.value_elim":0.93679,"p.value_classic":0.93851,"genes":"ABLIM3,ANLN,ATP8B1,CDKL1,CIBAR1,CYLD,DNAAF1,FGD5,FSCN1,ICAM1,IFT122,KCNJ10,LIMK2,LRRC61,MTSS1,NRP1,ONECUT2,P2RX7,RAPGEF2,S1PR1,SCIN,SNX10,STAP1"} {"GO.ID":"GO:0055086","Term":"nucleobase-containing small molecule metabolic process","Annotated":582,"Significant":34,"Expected":35.15,"Rank in p.value_classic":3308,"p.value_elim":0.93721,"p.value_classic":0.60709,"genes":"ACOT4,ACSL1,AK1,APOBEC3A,APOBEC3D,APOBEC3G,CD38,CMPK2,CTNS,DGAT2,DPYS,ENPP4,GIMAP7,GTPBP1,IDO1,IDO2,KARS1,LRRK2,NPR1,P2RX7,PARP10,PARP9,PDE4B,PDK4,PID1,PRTFDC1,RRM2,SLC2A6,SLC4A7,TK1,TYMP,TYMS,UNG,VPS9D1"} {"GO.ID":"GO:0009891","Term":"positive regulation of biosynthetic process","Annotated":2202,"Significant":157,"Expected":132.99,"Rank in p.value_classic":781,"p.value_elim":0.9383,"p.value_classic":0.01166,"genes":"ABLIM3,ADAM8,AGR2,AGT,AIM2,ANK2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDH5,CDK1,CHTF18,CIITA,CLEC6A,CLEC9A,CSF1,CXCL10,DAB2,DAZL,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,FCN1,GBP5,GCH1,GSDMD,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KLF4,KLRK1,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,MAF,MAFF,MAML3,MCOLN2,MEFV,MICAL2,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,P2RX4,P2RX7,PADI2,PARP9,PDE4B,PID1,PIM1,PKIB,PLSCR1,PTGER4,PYHIN1,RELB,RIPK2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF14,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WARS1,ZC3H12A,ZNF395"} {"GO.ID":"GO:0090101","Term":"negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","Annotated":121,"Significant":4,"Expected":7.31,"Rank in p.value_classic":4617,"p.value_elim":0.93867,"p.value_classic":0.93945,"genes":"CHRD,HTRA1,ONECUT2,TNFAIP6"} {"GO.ID":"GO:0045727","Term":"positive regulation of translation","Annotated":121,"Significant":4,"Expected":7.31,"Rank in p.value_classic":4618,"p.value_elim":0.93867,"p.value_classic":0.93945,"genes":"CCL5,CD28,DAZL,SAMD4A"} {"GO.ID":"GO:0045912","Term":"negative regulation of carbohydrate metabolic process","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4619,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"PLEK"} {"GO.ID":"GO:0044458","Term":"motile cilium assembly","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4620,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"DNAAF1"} {"GO.ID":"GO:0008089","Term":"anterograde axonal transport","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4621,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"DTNBP1"} {"GO.ID":"GO:1902459","Term":"positive regulation of stem cell population maintenance","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4622,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"LBH"} {"GO.ID":"GO:0071763","Term":"nuclear membrane organization","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4623,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"CHMP4C"} {"GO.ID":"GO:1901799","Term":"negative regulation of proteasomal protein catabolic process","Annotated":45,"Significant":1,"Expected":2.72,"Rank in p.value_classic":4624,"p.value_elim":0.93924,"p.value_classic":0.93969,"genes":"LAMP3"} {"GO.ID":"GO:1901575","Term":"organic substance catabolic process","Annotated":1790,"Significant":94,"Expected":108.11,"Rank in p.value_classic":4636,"p.value_elim":0.93933,"p.value_classic":0.94267,"genes":"ACOT4,ADAM8,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,ASB2,ATP13A2,CASP7,CBR3,CCNF,CEACAM1,CHAC1,CHMP4C,COLQ,CTRL,CTSL,CTSO,CTSS,CYP1A1,DAB2,DAZL,DERL3,DPYS,DTL,DTX3L,E2F1,ENPP2,ENPP4,ERAP2,FBXO6,FEM1C,FEN1,G6PC1,GGT5,GK,GLUL,GTPBP1,HCAR2,HSD11B1,IDO1,IDO2,IFI27,IL4I1,ISG20,LAMP3,LPL,LRP5,LRRK2,LYVE1,MAD2L1,NAAA,NUB1,OAS2,P2RX7,PDE3B,PDE4B,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PMAIP1,PML,PNPLA3,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RNF19B,RNF213,SAMD4A,SAT1,SCARF1,SGPL1,SIDT2,SLC11A1,SLC2A6,SOX17,TBX21,TRIM31,TSPAN15,TYMP,UBD,UBE2L6,UHRF1,UNG,WWP1,XRN1,ZC3H12A"} {"GO.ID":"GO:0006096","Term":"glycolytic process","Annotated":73,"Significant":2,"Expected":4.41,"Rank in p.value_classic":4625,"p.value_elim":0.93961,"p.value_classic":0.94019,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0043242","Term":"negative regulation of protein-containing complex disassembly","Annotated":73,"Significant":2,"Expected":4.41,"Rank in p.value_classic":4626,"p.value_elim":0.93961,"p.value_classic":0.94019,"genes":"SCIN,SPTBN4"} {"GO.ID":"GO:0019319","Term":"hexose biosynthetic process","Annotated":73,"Significant":2,"Expected":4.41,"Rank in p.value_classic":4627,"p.value_elim":0.93961,"p.value_classic":0.94019,"genes":"ATF3,G6PC1"} {"GO.ID":"GO:0034655","Term":"nucleobase-containing compound catabolic process","Annotated":467,"Significant":21,"Expected":28.2,"Rank in p.value_classic":4633,"p.value_elim":0.93979,"p.value_classic":0.94138,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,DAZL,DPYS,E2F1,ENPP4,FEN1,GTPBP1,ISG20,OAS2,P2RX7,PDE4B,SAMD4A,SIDT2,SLC11A1,SLC2A6,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:0051216","Term":"cartilage development","Annotated":166,"Significant":6,"Expected":10.03,"Rank in p.value_classic":4631,"p.value_elim":0.93979,"p.value_classic":0.9407,"genes":"COMP,EDN1,GHRL,MAF,SCIN,TYMS"} {"GO.ID":"GO:0030324","Term":"lung development","Annotated":166,"Significant":6,"Expected":10.03,"Rank in p.value_classic":4632,"p.value_elim":0.93979,"p.value_classic":0.9407,"genes":"AGR2,CELSR1,DNAAF1,EPAS1,HSD11B1,RXFP1"} {"GO.ID":"GO:0010927","Term":"cellular component assembly involved in morphogenesis","Annotated":98,"Significant":3,"Expected":5.92,"Rank in p.value_classic":4628,"p.value_elim":0.93986,"p.value_classic":0.94055,"genes":"ANK2,EDN1,MYOZ2"} {"GO.ID":"GO:0035113","Term":"embryonic appendage morphogenesis","Annotated":98,"Significant":3,"Expected":5.92,"Rank in p.value_classic":4629,"p.value_elim":0.93986,"p.value_classic":0.94055,"genes":"BCL2L11,IFT122,LRP5"} {"GO.ID":"GO:0030326","Term":"embryonic limb morphogenesis","Annotated":98,"Significant":3,"Expected":5.92,"Rank in p.value_classic":4630,"p.value_elim":0.93986,"p.value_classic":0.94055,"genes":"BCL2L11,IFT122,LRP5"} {"GO.ID":"GO:0031047","Term":"regulatory ncRNA-mediated gene silencing","Annotated":122,"Significant":4,"Expected":7.37,"Rank in p.value_classic":4634,"p.value_elim":0.94114,"p.value_classic":0.9419,"genes":"MIR503,PIWIL4,TDRD9,ZNFX1"} {"GO.ID":"GO:1903052","Term":"positive regulation of proteolysis involved in protein catabolic process","Annotated":122,"Significant":4,"Expected":7.37,"Rank in p.value_classic":4635,"p.value_elim":0.94114,"p.value_classic":0.9419,"genes":"DAB2,LRRK2,NUB1,PYHIN1"} {"GO.ID":"GO:0010604","Term":"positive regulation of macromolecule metabolic process","Annotated":2839,"Significant":198,"Expected":171.46,"Rank in p.value_classic":769,"p.value_elim":0.94199,"p.value_classic":0.01107,"genes":"ABLIM3,ADAM8,AGR2,AGT,AIM2,AMER1,ANK2,ASCL2,ATF3,ATF5,ATP13A2,AURKB,B2M,BACH1,BANK1,BAZ1A,BMAL2,BRCA1,BTN3A1,BTN3A2,C3,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDH5,CDK1,CDT1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,CSF1,CTSL,CTSS,CX3CR1,CXCL10,DAB2,DAZL,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,FAM107A,FAM20A,FAS,FAXDC2,FCN1,GBP5,GCH1,GRAMD4,GSAP,GSDMD,GTPBP1,HBEGF,HGF,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,IDO1,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MICAL2,MMD,MMP9,MUC1,MYBL2,NCF1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OSM,P2RX7,PADI2,PARP14,PARP3,PARP9,PDE4B,PID1,PIM1,PKIB,PLSCR1,PMAIP1,PML,PSME1,PSME2,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RIPK2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SEPTIN4,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOX17,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TRABD2A,TRIM22,TRIM31,UHRF1,VEGFC,WARS1,WEE1,ZC3H12A,ZNF395"} {"GO.ID":"GO:1903050","Term":"regulation of proteolysis involved in protein catabolic process","Annotated":210,"Significant":8,"Expected":12.68,"Rank in p.value_classic":4645,"p.value_elim":0.94238,"p.value_classic":0.94338,"genes":"DAB2,LAMP3,LRRK2,NUB1,PML,PSME1,PSME2,PYHIN1"} {"GO.ID":"GO:0150115","Term":"cell-substrate junction organization","Annotated":99,"Significant":3,"Expected":5.98,"Rank in p.value_classic":4637,"p.value_elim":0.94252,"p.value_classic":0.94318,"genes":"FAM107A,NRP1,S100A10"} {"GO.ID":"GO:0006892","Term":"post-Golgi vesicle-mediated transport","Annotated":99,"Significant":3,"Expected":5.98,"Rank in p.value_classic":4638,"p.value_elim":0.94252,"p.value_classic":0.94318,"genes":"DOP1A,OPTN,VAMP5"} {"GO.ID":"GO:0021766","Term":"hippocampus development","Annotated":74,"Significant":2,"Expected":4.47,"Rank in p.value_classic":4639,"p.value_elim":0.94262,"p.value_classic":0.94319,"genes":"DAB1,SEMA6B"} {"GO.ID":"GO:0060324","Term":"face development","Annotated":46,"Significant":1,"Expected":2.78,"Rank in p.value_classic":4640,"p.value_elim":0.94292,"p.value_classic":0.94334,"genes":"SGPL1"} {"GO.ID":"GO:0071985","Term":"multivesicular body sorting pathway","Annotated":46,"Significant":1,"Expected":2.78,"Rank in p.value_classic":4641,"p.value_elim":0.94292,"p.value_classic":0.94334,"genes":"CHMP4C"} {"GO.ID":"GO:0006984","Term":"ER-nucleus signaling pathway","Annotated":46,"Significant":1,"Expected":2.78,"Rank in p.value_classic":4642,"p.value_elim":0.94292,"p.value_classic":0.94334,"genes":"AGR2"} {"GO.ID":"GO:0030858","Term":"positive regulation of epithelial cell differentiation","Annotated":46,"Significant":1,"Expected":2.78,"Rank in p.value_classic":4643,"p.value_elim":0.94292,"p.value_classic":0.94334,"genes":"PLAAT4"} {"GO.ID":"GO:0055008","Term":"cardiac muscle tissue morphogenesis","Annotated":46,"Significant":1,"Expected":2.78,"Rank in p.value_classic":4644,"p.value_elim":0.94292,"p.value_classic":0.94334,"genes":"S1PR1"} {"GO.ID":"GO:0120031","Term":"plasma membrane bounded cell projection assembly","Annotated":490,"Significant":22,"Expected":29.59,"Rank in p.value_classic":4650,"p.value_elim":0.94472,"p.value_classic":0.94624,"genes":"ABLIM3,ANLN,ATP8B1,CDKL1,CIBAR1,CYLD,DNAAF1,FGD5,FSCN1,ICAM1,IFT122,KCNJ10,LIMK2,LRRC61,MTSS1,NRP1,ONECUT2,P2RX7,RAPGEF2,S1PR1,SNX10,STAP1"} {"GO.ID":"GO:0002062","Term":"chondrocyte differentiation","Annotated":100,"Significant":3,"Expected":6.04,"Rank in p.value_classic":4646,"p.value_elim":0.94507,"p.value_classic":0.94571,"genes":"COMP,MAF,SCIN"} {"GO.ID":"GO:0042177","Term":"negative regulation of protein catabolic process","Annotated":100,"Significant":3,"Expected":6.04,"Rank in p.value_classic":4647,"p.value_elim":0.94507,"p.value_classic":0.94571,"genes":"ATP13A2,LAMP3,MAD2L1"} {"GO.ID":"GO:0071482","Term":"cellular response to light stimulus","Annotated":100,"Significant":3,"Expected":6.04,"Rank in p.value_classic":4648,"p.value_elim":0.94507,"p.value_classic":0.94571,"genes":"AURKB,CDC25A,MMP9"} {"GO.ID":"GO:0046032","Term":"ADP catabolic process","Annotated":75,"Significant":2,"Expected":4.53,"Rank in p.value_classic":4649,"p.value_elim":0.94549,"p.value_classic":0.94604,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0048584","Term":"positive regulation of response to stimulus","Annotated":1899,"Significant":203,"Expected":114.69,"Rank in p.value_classic":32,"p.value_elim":0.94562,"p.value_classic":1.2e-17,"genes":"ACOD1,ADAM8,AGR2,AGT,AIM2,AMER1,APOL3,APPL2,ATF3,AURKB,B2M,BANK1,BCL2L11,BIRC5,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CARD16,CASP4,CASTOR1,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD1A,CD1C,CD274,CD28,CD300LF,CD38,CD40,CD74,CD80,CDH5,CEACAM1,CFB,CFH,CIBAR1,CLEC6A,COLEC12,CR1L,CSF1,CTLA4,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DDX60,DKK2,DLL1,EDA,EDN1,ENPP4,F2RL3,FAS,FCN1,FYB1,G0S2,GADD45B,GAREM1,GBP1,GBP2,GBP5,GHRL,GLIPR2,GPR183,GPR31,GRAMD4,GSDMD,HBEGF,HGF,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,ICAM1,IDO1,IFI35,IFIH1,IFIT5,IL12A,IL12RB1,IL15,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JAK2,KARS1,KITLG,KLRK1,LAG3,LILRA2,LITAF,LPL,LRRK2,LTA,LYN,MAD2L1,MCF2L,MEFV,MMP9,NCF1,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRK,NRP1,OAS3,OPTN,OSM,P2RX4,P2RX7,PARP14,PARP3,PARP9,PDE4B,PIM1,PLPP4,PLSCR1,PMAIP1,PML,PTGER4,PYHIN1,RALB,RAPGEF2,RASGRF1,RIPK2,RSAD2,S100A13,S1PR1,SCARF1,SCIMP,SECTM1,SEPTIN4,SERPING1,SLAMF1,SLAMF6,SLC11A1,SLC20A1,STAMBPL1,STAP1,STX1A,SUCNR1,TAP2,TBX21,TGM2,THBD,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFAIP8L3,TNFRSF11A,TNFRSF21,TNFSF10,TNFSF13B,TRIM22,TRIM31,TYRO3,UBD,VEGFC,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0032388","Term":"positive regulation of intracellular transport","Annotated":124,"Significant":4,"Expected":7.49,"Rank in p.value_classic":4651,"p.value_elim":0.94581,"p.value_classic":0.94653,"genes":"CDK1,DAB2,JAK2,ZC3H12A"} {"GO.ID":"GO:1904375","Term":"regulation of protein localization to cell periphery","Annotated":124,"Significant":4,"Expected":7.49,"Rank in p.value_classic":4652,"p.value_elim":0.94581,"p.value_classic":0.94653,"genes":"AGR2,DAB2,GBP1,PID1"} {"GO.ID":"GO:1903008","Term":"organelle disassembly","Annotated":169,"Significant":6,"Expected":10.21,"Rank in p.value_classic":4658,"p.value_elim":0.94596,"p.value_classic":0.9468,"genes":"ATP13A2,CDK1,MAP1LC3C,NOD2,OPTN,PLAAT3"} {"GO.ID":"GO:0032984","Term":"protein-containing complex disassembly","Annotated":233,"Significant":9,"Expected":14.07,"Rank in p.value_classic":4659,"p.value_elim":0.94604,"p.value_classic":0.94705,"genes":"CALCOCO2,CHMP4C,KIF18B,MAP1LC3C,MICAL2,PLEK,SCIN,SPTBN4,STMN1"} {"GO.ID":"GO:0060425","Term":"lung morphogenesis","Annotated":47,"Significant":1,"Expected":2.84,"Rank in p.value_classic":4653,"p.value_elim":0.94637,"p.value_classic":0.94678,"genes":"CELSR1"} {"GO.ID":"GO:0042073","Term":"intraciliary transport","Annotated":47,"Significant":1,"Expected":2.84,"Rank in p.value_classic":4654,"p.value_elim":0.94637,"p.value_classic":0.94678,"genes":"IFT122"} {"GO.ID":"GO:0051646","Term":"mitochondrion localization","Annotated":47,"Significant":1,"Expected":2.84,"Rank in p.value_classic":4655,"p.value_elim":0.94637,"p.value_classic":0.94678,"genes":"LRRK2"} {"GO.ID":"GO:0045599","Term":"negative regulation of fat cell differentiation","Annotated":47,"Significant":1,"Expected":2.84,"Rank in p.value_classic":4656,"p.value_elim":0.94637,"p.value_classic":0.94678,"genes":"E2F1"} {"GO.ID":"GO:0016601","Term":"Rac protein signal transduction","Annotated":47,"Significant":1,"Expected":2.84,"Rank in p.value_classic":4657,"p.value_elim":0.94637,"p.value_classic":0.94678,"genes":"RASGRF1"} {"GO.ID":"GO:0019318","Term":"hexose metabolic process","Annotated":191,"Significant":7,"Expected":11.54,"Rank in p.value_classic":4660,"p.value_elim":0.94657,"p.value_classic":0.94746,"genes":"ATF3,G6PC1,GHRL,LRP5,PDK4,PMAIP1,SLC45A3"} {"GO.ID":"GO:0045732","Term":"positive regulation of protein catabolic process","Annotated":191,"Significant":7,"Expected":11.54,"Rank in p.value_classic":4661,"p.value_elim":0.94657,"p.value_classic":0.94746,"genes":"ADAM8,AMER1,DAB2,DTL,LRRK2,NUB1,SOX17"} {"GO.ID":"GO:0010586","Term":"miRNA metabolic process","Annotated":101,"Significant":3,"Expected":6.1,"Rank in p.value_classic":4662,"p.value_elim":0.94751,"p.value_classic":0.94813,"genes":"AGT,KLF4,ZC3H12A"} {"GO.ID":"GO:0048593","Term":"camera-type eye morphogenesis","Annotated":101,"Significant":3,"Expected":6.1,"Rank in p.value_classic":4663,"p.value_elim":0.94751,"p.value_classic":0.94813,"genes":"DLL1,IFT122,LRP5"} {"GO.ID":"GO:0030323","Term":"respiratory tube development","Annotated":170,"Significant":6,"Expected":10.27,"Rank in p.value_classic":4665,"p.value_elim":0.94788,"p.value_classic":0.94871,"genes":"AGR2,CELSR1,DNAAF1,EPAS1,HSD11B1,RXFP1"} {"GO.ID":"GO:0046364","Term":"monosaccharide biosynthetic process","Annotated":76,"Significant":2,"Expected":4.59,"Rank in p.value_classic":4666,"p.value_elim":0.94823,"p.value_classic":0.94875,"genes":"ATF3,G6PC1"} {"GO.ID":"GO:0008589","Term":"regulation of smoothened signaling pathway","Annotated":76,"Significant":2,"Expected":4.59,"Rank in p.value_classic":4667,"p.value_elim":0.94823,"p.value_classic":0.94875,"genes":"CIBAR1,IFT122"} {"GO.ID":"GO:0043588","Term":"skin development","Annotated":192,"Significant":7,"Expected":11.6,"Rank in p.value_classic":4668,"p.value_elim":0.94838,"p.value_classic":0.94925,"genes":"COMP,DLL1,EDA,KLF4,OVOL1,PLAAT4,STMN1"} {"GO.ID":"GO:2000059","Term":"negative regulation of ubiquitin-dependent protein catabolic process","Annotated":48,"Significant":1,"Expected":2.9,"Rank in p.value_classic":4669,"p.value_elim":0.94961,"p.value_classic":0.95,"genes":"PML"} {"GO.ID":"GO:0010823","Term":"negative regulation of mitochondrion organization","Annotated":48,"Significant":1,"Expected":2.9,"Rank in p.value_classic":4670,"p.value_elim":0.94961,"p.value_classic":0.95,"genes":"HGF"} {"GO.ID":"GO:0009311","Term":"oligosaccharide metabolic process","Annotated":48,"Significant":1,"Expected":2.9,"Rank in p.value_classic":4671,"p.value_elim":0.94961,"p.value_classic":0.95,"genes":"GAL3ST4"} {"GO.ID":"GO:0051603","Term":"proteolysis involved in protein catabolic process","Annotated":703,"Significant":33,"Expected":42.46,"Rank in p.value_classic":4675,"p.value_elim":0.94989,"p.value_classic":0.9516,"genes":"ASB2,CCNF,CHMP4C,CTSL,CTSO,CTSS,DAB2,DERL3,DTL,DTX3L,FBXO6,FEM1C,IFI27,LAMP3,LRRK2,NUB1,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RNF19B,RNF213,TBX21,TRIM31,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0072523","Term":"purine-containing compound catabolic process","Annotated":126,"Significant":4,"Expected":7.61,"Rank in p.value_classic":4672,"p.value_elim":0.95014,"p.value_classic":0.95081,"genes":"ENPP4,P2RX7,PDE4B,SLC2A6"} {"GO.ID":"GO:0019364","Term":"pyridine nucleotide catabolic process","Annotated":77,"Significant":2,"Expected":4.65,"Rank in p.value_classic":4673,"p.value_elim":0.95083,"p.value_classic":0.95133,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0061014","Term":"positive regulation of mRNA catabolic process","Annotated":103,"Significant":3,"Expected":6.22,"Rank in p.value_classic":4676,"p.value_elim":0.9521,"p.value_classic":0.95268,"genes":"GTPBP1,SAMD4A,ZC3H12A"} {"GO.ID":"GO:0006890","Term":"retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum","Annotated":49,"Significant":1,"Expected":2.96,"Rank in p.value_classic":4677,"p.value_elim":0.95266,"p.value_classic":0.95303,"genes":"TAPBP"} {"GO.ID":"GO:0009181","Term":"purine ribonucleoside diphosphate catabolic process","Annotated":78,"Significant":2,"Expected":4.71,"Rank in p.value_classic":4678,"p.value_elim":0.95331,"p.value_classic":0.95379,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0009137","Term":"purine nucleoside diphosphate catabolic process","Annotated":78,"Significant":2,"Expected":4.71,"Rank in p.value_classic":4679,"p.value_elim":0.95331,"p.value_classic":0.95379,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:1901800","Term":"positive regulation of proteasomal protein catabolic process","Annotated":104,"Significant":3,"Expected":6.28,"Rank in p.value_classic":4680,"p.value_elim":0.95425,"p.value_classic":0.95481,"genes":"DAB2,LRRK2,NUB1"} {"GO.ID":"GO:0061013","Term":"regulation of mRNA catabolic process","Annotated":174,"Significant":6,"Expected":10.51,"Rank in p.value_classic":4681,"p.value_elim":0.95499,"p.value_classic":0.95572,"genes":"DAZL,E2F1,GTPBP1,SAMD4A,SLC11A1,ZC3H12A"} {"GO.ID":"GO:0007411","Term":"axon guidance","Annotated":174,"Significant":6,"Expected":10.51,"Rank in p.value_classic":4682,"p.value_elim":0.95499,"p.value_classic":0.95572,"genes":"EDN1,EGR2,EPHB3,NRCAM,NRP1,SEMA6B"} {"GO.ID":"GO:0097485","Term":"neuron projection guidance","Annotated":174,"Significant":6,"Expected":10.51,"Rank in p.value_classic":4683,"p.value_elim":0.95499,"p.value_classic":0.95572,"genes":"EDN1,EGR2,EPHB3,NRCAM,NRP1,SEMA6B"} {"GO.ID":"GO:0048588","Term":"developmental cell growth","Annotated":196,"Significant":7,"Expected":11.84,"Rank in p.value_classic":4684,"p.value_elim":0.95508,"p.value_classic":0.95586,"genes":"EDN1,FSTL4,NRCAM,NRN1,NRP1,SEMA6B,SYT1"} {"GO.ID":"GO:0048523","Term":"negative regulation of cellular process","Annotated":4065,"Significant":274,"Expected":245.51,"Rank in p.value_classic":810,"p.value_elim":0.95515,"p.value_classic":0.01379,"genes":"ACOD1,ADAM8,ADORA3,AGT,AIFM2,AIM2,AMER1,ANK2,ANTXR1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ASIC1,ATF3,ATF5,ATP1B2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF3,BAZ1A,BCL2A1,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,BUB1B,CAMK2D,CARD16,CASTOR1,CCL5,CCL8,CCNF,CD274,CD28,CD300LF,CD38,CD74,CD80,CD83,CDC45,CDC6,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHMP4C,CHRD,CIITA,CISH,CLSPN,COMP,CRHBP,CTLA4,CTNS,CX3CR1,CXCL10,CXCL11,CXCL9,CYLD,DAB1,DAB2,DAZL,DEPTOR,DERL3,DHFR,DHRS3,DKK2,DLL1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F8,EDN1,EME1,ETV7,F2RL3,FAM107A,FAS,FBXO6,FGL1,FGL2,FSTL4,GBP1,GBP7,GCH1,GHRL,GRAMD4,GTPBP1,GTSE1,HBEGF,HELLS,HESX1,HGF,HLA-A,HLA-B,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFIT3,IFITM1,IFT122,IL12A,IL15RA,IL1RN,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,JAK2,JAK3,KCNE5,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMP3,LBH,LILRA2,LILRB3,LIMK2,LITAF,LRP5,LRRK2,LTA,LYN,MAD2L1,MAF,MAFF,MEFV,MERTK,MIR503,MMP9,MTSS1,MUC1,MVP,MYOZ2,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRP1,NUF2,OAS3,ONECUT2,OPTN,ORC1,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCDHGC3,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLAAT4,PLEK,PLSCR1,PLXNA2,PML,PPM1E,PROK2,PRRT2,PTGER4,PTPRU,RAPGEF2,RELB,RGS18,RMI2,RNF213,RSAD2,RTN4RL1,S1PR1,SAMD4A,SBNO2,SCIN,SEMA6B,SESN3,SLAMF1,SLAMF8,SLC11A1,SOCS1,SOX17,SPC24,SPC25,SPTBN4,SRI,SSTR2,STAP1,STAT1,STAT2,STMN1,SYNE1,TAL1,TANK,TBX21,TDRD9,TESC,TFEC,THBD,TICRR,TLR8,TMEM109,TMEM119,TMEM176A,TMEM176B,TMSB10,TNFAIP6,TNFRSF14,TNFRSF21,TNFSF18,TOP2A,TRABD2A,TRDN,TRIM22,TRIM31,TSPAN15,TSPAN32,TYMS,TYRO3,UHRF1,UNG,VEGFC,WARS1,WDR76,WEE1,WWP1,XAF1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1,ZWINT"} {"GO.ID":"GO:0050435","Term":"amyloid-beta metabolic process","Annotated":50,"Significant":1,"Expected":3.02,"Rank in p.value_classic":4685,"p.value_elim":0.95552,"p.value_classic":0.95588,"genes":"GSAP"} {"GO.ID":"GO:0035088","Term":"establishment or maintenance of apical/basal cell polarity","Annotated":50,"Significant":1,"Expected":3.02,"Rank in p.value_classic":4686,"p.value_elim":0.95552,"p.value_classic":0.95588,"genes":"FSCN1"} {"GO.ID":"GO:0010921","Term":"regulation of phosphatase activity","Annotated":50,"Significant":1,"Expected":3.02,"Rank in p.value_classic":4687,"p.value_elim":0.95552,"p.value_classic":0.95588,"genes":"PLEK"} {"GO.ID":"GO:0061245","Term":"establishment or maintenance of bipolar cell polarity","Annotated":50,"Significant":1,"Expected":3.02,"Rank in p.value_classic":4688,"p.value_elim":0.95552,"p.value_classic":0.95588,"genes":"FSCN1"} {"GO.ID":"GO:0060537","Term":"muscle tissue development","Annotated":342,"Significant":14,"Expected":20.66,"Rank in p.value_classic":4692,"p.value_elim":0.95563,"p.value_classic":0.95668,"genes":"ASB2,ATF3,CDK1,CENPF,CXADR,DLL1,EDN1,EGR2,MAFF,MYOZ2,PIM1,S1PR1,SYNE1,VAMP5"} {"GO.ID":"GO:0030512","Term":"negative regulation of transforming growth factor beta receptor signaling pathway","Annotated":79,"Significant":2,"Expected":4.77,"Rank in p.value_classic":4689,"p.value_elim":0.95567,"p.value_classic":0.95613,"genes":"HTRA1,ONECUT2"} {"GO.ID":"GO:1902117","Term":"positive regulation of organelle assembly","Annotated":79,"Significant":2,"Expected":4.77,"Rank in p.value_classic":4690,"p.value_elim":0.95567,"p.value_classic":0.95613,"genes":"FSCN1,RALB"} {"GO.ID":"GO:0072665","Term":"protein localization to vacuole","Annotated":79,"Significant":2,"Expected":4.77,"Rank in p.value_classic":4691,"p.value_elim":0.95567,"p.value_classic":0.95613,"genes":"ATP13A2,GBP1"} {"GO.ID":"GO:0030111","Term":"regulation of Wnt signaling pathway","Annotated":281,"Significant":11,"Expected":16.97,"Rank in p.value_classic":4693,"p.value_elim":0.9558,"p.value_classic":0.95674,"genes":"AMER1,CYLD,DAB2,DKK2,EDA,KREMEN1,LRRK2,PTPRU,RNF213,SOX17,TRABD2A"} {"GO.ID":"GO:0061136","Term":"regulation of proteasomal protein catabolic process","Annotated":175,"Significant":6,"Expected":10.57,"Rank in p.value_classic":4694,"p.value_elim":0.95662,"p.value_classic":0.95734,"genes":"DAB2,LAMP3,LRRK2,NUB1,PSME1,PSME2"} {"GO.ID":"GO:0031175","Term":"neuron projection development","Annotated":823,"Significant":39,"Expected":49.71,"Rank in p.value_classic":4703,"p.value_elim":0.95699,"p.value_classic":0.95863,"genes":"ATP1B2,B2M,C21orf91,CD38,DAB1,DAB2,DHFR,DTNBP1,EDN1,EGR2,EPHB3,FSTL4,GHRL,GRIN3A,IL15RA,JAK2,KIF26A,KLF4,KREMEN1,LRRK2,LYN,NRCAM,NRN1,NRP1,NYAP2,OLIG1,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,SCARF1,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1,SYT1,TNFRSF21,WEE1"} {"GO.ID":"GO:0006511","Term":"ubiquitin-dependent protein catabolic process","Annotated":559,"Significant":25,"Expected":33.76,"Rank in p.value_classic":4699,"p.value_elim":0.95711,"p.value_classic":0.95843,"genes":"ASB2,CCNF,CHMP4C,DAB2,DTL,DTX3L,FBXO6,FEM1C,IFI27,LRRK2,NUB1,PML,PSMB10,PSMB8,PSMB9,PYHIN1,RHOBTB3,RNF19B,RNF213,TBX21,TRIM31,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0090092","Term":"regulation of transmembrane receptor protein serine/threonine kinase signaling pathway","Annotated":219,"Significant":8,"Expected":13.23,"Rank in p.value_classic":4695,"p.value_elim":0.95722,"p.value_classic":0.95802,"genes":"CDH5,CHRD,DAB2,FSTL4,HTRA1,JAK2,ONECUT2,TNFAIP6"} {"GO.ID":"GO:2000058","Term":"regulation of ubiquitin-dependent protein catabolic process","Annotated":153,"Significant":5,"Expected":9.24,"Rank in p.value_classic":4696,"p.value_elim":0.95747,"p.value_classic":0.95813,"genes":"DAB2,LRRK2,NUB1,PML,PYHIN1"} {"GO.ID":"GO:0170033","Term":"L-amino acid metabolic process","Annotated":130,"Significant":4,"Expected":7.85,"Rank in p.value_classic":4700,"p.value_elim":0.95786,"p.value_classic":0.95846,"genes":"DHFR,GLUL,IL4I1,SERINC5"} {"GO.ID":"GO:0009581","Term":"detection of external stimulus","Annotated":80,"Significant":2,"Expected":4.83,"Rank in p.value_classic":4697,"p.value_elim":0.95791,"p.value_classic":0.95836,"genes":"CDS1,PKD1L3"} {"GO.ID":"GO:0072526","Term":"pyridine-containing compound catabolic process","Annotated":80,"Significant":2,"Expected":4.83,"Rank in p.value_classic":4698,"p.value_elim":0.95791,"p.value_classic":0.95836,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0050810","Term":"regulation of steroid biosynthetic process","Annotated":51,"Significant":1,"Expected":3.08,"Rank in p.value_classic":4701,"p.value_elim":0.95821,"p.value_classic":0.95855,"genes":"DAB2"} {"GO.ID":"GO:0001658","Term":"branching involved in ureteric bud morphogenesis","Annotated":51,"Significant":1,"Expected":3.08,"Rank in p.value_classic":4702,"p.value_elim":0.95821,"p.value_classic":0.95855,"genes":"AGT"} {"GO.ID":"GO:0006665","Term":"sphingolipid metabolic process","Annotated":131,"Significant":4,"Expected":7.91,"Rank in p.value_classic":4705,"p.value_elim":0.95961,"p.value_classic":0.96019,"genes":"ENPP2,NAAA,P2RX7,SGPL1"} {"GO.ID":"GO:0006401","Term":"RNA catabolic process","Annotated":284,"Significant":11,"Expected":17.15,"Rank in p.value_classic":4709,"p.value_elim":0.95962,"p.value_classic":0.96049,"genes":"DAZL,E2F1,FEN1,GTPBP1,ISG20,OAS2,SAMD4A,SIDT2,SLC11A1,XRN1,ZC3H12A"} {"GO.ID":"GO:0009191","Term":"ribonucleoside diphosphate catabolic process","Annotated":81,"Significant":2,"Expected":4.89,"Rank in p.value_classic":4707,"p.value_elim":0.96004,"p.value_classic":0.96048,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0009582","Term":"detection of abiotic stimulus","Annotated":81,"Significant":2,"Expected":4.89,"Rank in p.value_classic":4708,"p.value_elim":0.96004,"p.value_classic":0.96048,"genes":"CDS1,PKD1L3"} {"GO.ID":"GO:0006612","Term":"protein targeting to membrane","Annotated":107,"Significant":3,"Expected":6.46,"Rank in p.value_classic":4710,"p.value_elim":0.96017,"p.value_classic":0.96068,"genes":"NCF1,RTP4,ZDHHC19"} {"GO.ID":"GO:0031329","Term":"regulation of cellular catabolic process","Annotated":620,"Significant":28,"Expected":37.45,"Rank in p.value_classic":4712,"p.value_elim":0.96032,"p.value_classic":0.96164,"genes":"ADAM8,ATP13A2,ATP6V0D2,CALCOCO2,DAZL,DEPTOR,DRAM1,DTX3L,E2F1,GTPBP1,HGF,LAMP3,LRRK2,MEFV,NOD2,OPTN,P2RX7,RALB,RIPK2,RUFY4,SAMD4A,SESN3,SLC11A1,SLC2A6,TPCN1,TRIM22,TSPAN15,ZC3H12A"} {"GO.ID":"GO:0006338","Term":"chromatin remodeling","Annotated":545,"Significant":24,"Expected":32.92,"Rank in p.value_classic":4717,"p.value_elim":0.96189,"p.value_classic":0.96308,"genes":"BAZ1A,BCL6,BRCA1,CDK1,CHAF1B,DTX3L,EPOP,ERCC6L,H2BC21,HELLS,HJURP,IRF4,JADE2,JAK2,MCM2,NPM2,OIP5,PADI2,RAD54B,RAD54L,TDRD9,TGM2,UHRF1,ZNFX1"} {"GO.ID":"GO:0005976","Term":"polysaccharide metabolic process","Annotated":82,"Significant":2,"Expected":4.95,"Rank in p.value_classic":4713,"p.value_elim":0.96207,"p.value_classic":0.96249,"genes":"G6PC1,PCDH12"} {"GO.ID":"GO:0001578","Term":"microtubule bundle formation","Annotated":82,"Significant":2,"Expected":4.95,"Rank in p.value_classic":4714,"p.value_elim":0.96207,"p.value_classic":0.96249,"genes":"DNAAF1,LRRC61"} {"GO.ID":"GO:0090596","Term":"sensory organ morphogenesis","Annotated":201,"Significant":7,"Expected":12.14,"Rank in p.value_classic":4716,"p.value_elim":0.96235,"p.value_classic":0.96304,"genes":"DLL1,EDN1,HESX1,IFT122,LRP5,SOBP,TIFAB"} {"GO.ID":"GO:0045010","Term":"actin nucleation","Annotated":53,"Significant":1,"Expected":3.2,"Rank in p.value_classic":4718,"p.value_elim":0.96311,"p.value_classic":0.96343,"genes":"SCIN"} {"GO.ID":"GO:0016126","Term":"sterol biosynthetic process","Annotated":53,"Significant":1,"Expected":3.2,"Rank in p.value_classic":4719,"p.value_elim":0.96311,"p.value_classic":0.96343,"genes":"FAXDC2"} {"GO.ID":"GO:1902903","Term":"regulation of supramolecular fiber organization","Annotated":349,"Significant":14,"Expected":21.08,"Rank in p.value_classic":4721,"p.value_elim":0.96346,"p.value_classic":0.96436,"genes":"CDH5,EDN1,MTSS1,NRP1,PLEK,PPM1E,PTGER4,PXN,S100A10,S1PR1,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0007163","Term":"establishment or maintenance of cell polarity","Annotated":202,"Significant":7,"Expected":12.2,"Rank in p.value_classic":4720,"p.value_elim":0.96367,"p.value_classic":0.96434,"genes":"AMOT,CDH5,DYNLT1,FSCN1,MAD2L1,NDC80,WEE1"} {"GO.ID":"GO:0022604","Term":"regulation of cell morphogenesis","Annotated":224,"Significant":8,"Expected":13.53,"Rank in p.value_classic":4723,"p.value_elim":0.96389,"p.value_classic":0.96459,"genes":"CCL13,CCL7,ENPP2,FGD5,FMNL2,ITGA7,PLXNA2,SYT1"} {"GO.ID":"GO:0010507","Term":"negative regulation of autophagy","Annotated":83,"Significant":2,"Expected":5.01,"Rank in p.value_classic":4722,"p.value_elim":0.964,"p.value_classic":0.96441,"genes":"HGF,LRRK2"} {"GO.ID":"GO:0016055","Term":"Wnt signaling pathway","Annotated":390,"Significant":16,"Expected":23.55,"Rank in p.value_classic":4726,"p.value_elim":0.96405,"p.value_classic":0.965,"genes":"AMER1,CELSR1,CYLD,DAB2,DKK2,EDA,EDN1,HESX1,KLF4,KREMEN1,LRP5,LRRK2,PTPRU,RNF213,SOX17,TRABD2A"} {"GO.ID":"GO:0008064","Term":"regulation of actin polymerization or depolymerization","Annotated":134,"Significant":4,"Expected":8.09,"Rank in p.value_classic":4724,"p.value_elim":0.96446,"p.value_classic":0.96499,"genes":"PLEK,SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0010976","Term":"positive regulation of neuron projection development","Annotated":134,"Significant":4,"Expected":8.09,"Rank in p.value_classic":4725,"p.value_elim":0.96446,"p.value_classic":0.96499,"genes":"ATP1B2,LYN,RAPGEF2,SCARF1"} {"GO.ID":"GO:0198738","Term":"cell-cell signaling by wnt","Annotated":391,"Significant":16,"Expected":23.61,"Rank in p.value_classic":4734,"p.value_elim":0.965,"p.value_classic":0.96593,"genes":"AMER1,CELSR1,CYLD,DAB2,DKK2,EDA,EDN1,HESX1,KLF4,KREMEN1,LRP5,LRRK2,PTPRU,RNF213,SOX17,TRABD2A"} {"GO.ID":"GO:0060415","Term":"muscle tissue morphogenesis","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4727,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"S1PR1"} {"GO.ID":"GO:0006998","Term":"nuclear envelope organization","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4728,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"CHMP4C"} {"GO.ID":"GO:0035904","Term":"aorta development","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4729,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"EGR2"} {"GO.ID":"GO:0061462","Term":"protein localization to lysosome","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4730,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"ATP13A2"} {"GO.ID":"GO:0051149","Term":"positive regulation of muscle cell differentiation","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4731,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"EDN1"} {"GO.ID":"GO:0046513","Term":"ceramide biosynthetic process","Annotated":54,"Significant":1,"Expected":3.26,"Rank in p.value_classic":4732,"p.value_elim":0.96534,"p.value_classic":0.96565,"genes":"P2RX7"} {"GO.ID":"GO:0022904","Term":"respiratory electron transport chain","Annotated":110,"Significant":3,"Expected":6.64,"Rank in p.value_classic":4733,"p.value_elim":0.96537,"p.value_classic":0.96582,"genes":"AIFM2,CDK1,SCO2"} {"GO.ID":"GO:0019941","Term":"modification-dependent protein catabolic process","Annotated":569,"Significant":25,"Expected":34.37,"Rank in p.value_classic":4737,"p.value_elim":0.96573,"p.value_classic":0.96684,"genes":"ASB2,CCNF,CHMP4C,DAB2,DTL,DTX3L,FBXO6,FEM1C,IFI27,LRRK2,NUB1,PML,PSMB10,PSMB8,PSMB9,PYHIN1,RHOBTB3,RNF19B,RNF213,TBX21,TRIM31,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0009134","Term":"nucleoside diphosphate catabolic process","Annotated":84,"Significant":2,"Expected":5.07,"Rank in p.value_classic":4735,"p.value_elim":0.96584,"p.value_classic":0.96623,"genes":"P2RX7,SLC2A6"} {"GO.ID":"GO:0030832","Term":"regulation of actin filament length","Annotated":135,"Significant":4,"Expected":8.15,"Rank in p.value_classic":4736,"p.value_elim":0.96596,"p.value_classic":0.96646,"genes":"PLEK,SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0010498","Term":"proteasomal protein catabolic process","Annotated":492,"Significant":21,"Expected":29.71,"Rank in p.value_classic":4740,"p.value_elim":0.96649,"p.value_classic":0.9675,"genes":"ASB2,CCNF,DAB2,DERL3,DTL,FBXO6,FEM1C,IFI27,LAMP3,LRRK2,NUB1,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,RHOBTB3,TBX21,WWP1"} {"GO.ID":"GO:0043488","Term":"regulation of mRNA stability","Annotated":159,"Significant":5,"Expected":9.6,"Rank in p.value_classic":4738,"p.value_elim":0.9665,"p.value_classic":0.96705,"genes":"DAZL,E2F1,SAMD4A,SLC11A1,ZC3H12A"} {"GO.ID":"GO:0007006","Term":"mitochondrial membrane organization","Annotated":111,"Significant":3,"Expected":6.7,"Rank in p.value_classic":4739,"p.value_elim":0.96695,"p.value_classic":0.96739,"genes":"BCL2L11,CIBAR1,PMAIP1"} {"GO.ID":"GO:0030163","Term":"protein catabolic process","Annotated":912,"Significant":43,"Expected":55.08,"Rank in p.value_classic":4746,"p.value_elim":0.9672,"p.value_classic":0.96858,"genes":"ADAM8,AMER1,ASB2,ATP13A2,CASP7,CCNF,CEACAM1,CHMP4C,CTRL,CTSL,CTSO,CTSS,DAB2,DERL3,DTL,DTX3L,FBXO6,FEM1C,IFI27,LAMP3,LRRK2,MAD2L1,NUB1,P2RX7,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RNF19B,RNF213,SOX17,TBX21,TRIM31,TSPAN15,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0099518","Term":"vesicle cytoskeletal trafficking","Annotated":55,"Significant":1,"Expected":3.32,"Rank in p.value_classic":4741,"p.value_elim":0.96744,"p.value_classic":0.96773,"genes":"DTNBP1"} {"GO.ID":"GO:0001738","Term":"morphogenesis of a polarized epithelium","Annotated":55,"Significant":1,"Expected":3.32,"Rank in p.value_classic":4742,"p.value_elim":0.96744,"p.value_classic":0.96773,"genes":"CELSR1"} {"GO.ID":"GO:0032456","Term":"endocytic recycling","Annotated":85,"Significant":2,"Expected":5.13,"Rank in p.value_classic":4743,"p.value_elim":0.96759,"p.value_classic":0.96796,"genes":"ARL4C,LMTK2"} {"GO.ID":"GO:0001843","Term":"neural tube closure","Annotated":85,"Significant":2,"Expected":5.13,"Rank in p.value_classic":4744,"p.value_elim":0.96759,"p.value_classic":0.96796,"genes":"CELSR1,IFT122"} {"GO.ID":"GO:0042176","Term":"regulation of protein catabolic process","Annotated":333,"Significant":13,"Expected":20.11,"Rank in p.value_classic":4747,"p.value_elim":0.96784,"p.value_classic":0.96863,"genes":"ADAM8,AMER1,ATP13A2,DAB2,DTL,LAMP3,LRRK2,MAD2L1,NUB1,PSME1,PSME2,SOX17,TSPAN15"} {"GO.ID":"GO:0005996","Term":"monosaccharide metabolic process","Annotated":206,"Significant":7,"Expected":12.44,"Rank in p.value_classic":4748,"p.value_elim":0.96855,"p.value_classic":0.96914,"genes":"ATF3,G6PC1,GHRL,LRP5,PDK4,PMAIP1,SLC45A3"} {"GO.ID":"GO:0051234","Term":"establishment of localization","Annotated":3713,"Significant":238,"Expected":224.25,"Rank in p.value_classic":1617,"p.value_elim":0.96924,"p.value_classic":0.14058,"genes":"ABCB1,ABCC11,ABCG2,ABLIM3,ACSL1,ADAM8,ADORA3,AGR2,AGT,ANK2,ANKH,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARL4C,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BCL2A1,BCL2L11,BIRC5,C1QTNF5,C2,C3,C4A,C4B,CACNA2D3,CADPS2,CALHM6,CAMK2D,CCL5,CCL8,CD163,CD300LF,CD38,CD74,CD93,CDCA5,CDK1,CDT1,CEACAM1,CENPF,CHMP4C,CLEC10A,CLEC9A,CLIC5,COLEC12,COLQ,COMP,CRHBP,CTNS,CTSL,CTSS,CXADR,CXCL10,CXCL11,CXCL9,CYSLTR1,DAB2,DERL3,DLL1,DNAAF1,DNM1,DOP1A,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EEPD1,EGR2,EML4,ENPP2,ERC2,EXOC3L1,EXOC3L4,F2RL3,FCN1,FLVCR2,G6PC1,GABRA3,GBP5,GCNT3,GHRL,GJD3,GRAMD1B,GRIN3A,GSDMA,GSDMD,HAVCR1,HCAR2,HLA-DRB1,HLA-F,HRH2,IFI27,IFT122,IGF2R,IL12A,IL15,IL15RA,IL1RN,ITSN1,JAK2,KCNE5,KCNJ10,KCNJ15,KCNJ2,KPNA5,LAMP3,LAMP5,LGALS3BP,LILRA2,LIMK2,LMTK2,LRP5,LRRK2,LY75,LYN,LYVE1,MAD2L1,MAP1LC3C,MCOLN2,MCTP2,MERTK,MMP9,MVP,MYO7B,MYOF,NCF1,NDC80,NECAB2,NOD2,NPR1,NR4A3,NRP1,NUF2,NUSAP1,OAS2,OCA2,OPTN,OSBPL6,OSM,P2RX4,P2RX7,PDE4B,PID1,PIM1,PKD1L3,PLEK,PLPP4,PLSCR1,PLSCR4,PMAIP1,PML,PRRT2,RAB20,RALB,RBP7,REEP1,REPS2,RHOBTB3,RSAD2,RTP4,S100A10,S100A13,SCARF1,SCIN,SCN4B,SEPTIN4,SERINC5,SIDT1,SIDT2,SLAMF1,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SNX10,SNX20,SOAT1,SPC24,SPC25,SPTBN4,SRI,STAP1,STEAP4,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAP1,TAP2,TAPBP,TESC,TGM2,TICAM2,TIFAB,TMEM109,TMEM144,TNFAIP2,TNFAIP8L3,TNFRSF11A,TPCN1,TRDN,TTC39B,TYRO3,USP6NL,VAMP5,VEGFC,VPS9D1,WWP1,XKR6,ZC3H12A,ZDHHC19,ZWINT"} {"GO.ID":"GO:0006672","Term":"ceramide metabolic process","Annotated":86,"Significant":2,"Expected":5.19,"Rank in p.value_classic":4749,"p.value_elim":0.96925,"p.value_classic":0.96961,"genes":"P2RX7,SGPL1"} {"GO.ID":"GO:0060606","Term":"tube closure","Annotated":86,"Significant":2,"Expected":5.19,"Rank in p.value_classic":4750,"p.value_elim":0.96925,"p.value_classic":0.96961,"genes":"CELSR1,IFT122"} {"GO.ID":"GO:1903078","Term":"positive regulation of protein localization to plasma membrane","Annotated":56,"Significant":1,"Expected":3.38,"Rank in p.value_classic":4751,"p.value_elim":0.96941,"p.value_classic":0.96969,"genes":"AGR2"} {"GO.ID":"GO:0009154","Term":"purine ribonucleotide catabolic process","Annotated":113,"Significant":3,"Expected":6.82,"Rank in p.value_classic":4752,"p.value_elim":0.96992,"p.value_classic":0.97033,"genes":"P2RX7,PDE4B,SLC2A6"} {"GO.ID":"GO:0051650","Term":"establishment of vesicle localization","Annotated":185,"Significant":6,"Expected":11.17,"Rank in p.value_classic":4753,"p.value_elim":0.97023,"p.value_classic":0.97077,"genes":"ATP13A2,CADPS2,DNM1,DTNBP1,LIMK2,LRRK2"} {"GO.ID":"GO:0014020","Term":"primary neural tube formation","Annotated":87,"Significant":2,"Expected":5.25,"Rank in p.value_classic":4754,"p.value_elim":0.97083,"p.value_classic":0.97117,"genes":"CELSR1,IFT122"} {"GO.ID":"GO:0090630","Term":"activation of GTPase activity","Annotated":87,"Significant":2,"Expected":5.25,"Rank in p.value_classic":4755,"p.value_elim":0.97083,"p.value_classic":0.97117,"genes":"RASGRF1,USP6NL"} {"GO.ID":"GO:0070509","Term":"calcium ion import","Annotated":57,"Significant":1,"Expected":3.44,"Rank in p.value_classic":4756,"p.value_elim":0.97126,"p.value_classic":0.97153,"genes":"PLPP4"} {"GO.ID":"GO:0060675","Term":"ureteric bud morphogenesis","Annotated":57,"Significant":1,"Expected":3.44,"Rank in p.value_classic":4757,"p.value_elim":0.97126,"p.value_classic":0.97153,"genes":"AGT"} {"GO.ID":"GO:0018205","Term":"peptidyl-lysine modification","Annotated":139,"Significant":4,"Expected":8.39,"Rank in p.value_classic":4758,"p.value_elim":0.97137,"p.value_classic":0.97181,"genes":"EGR2,IFIH1,PML,STX1A"} {"GO.ID":"GO:0009259","Term":"ribonucleotide metabolic process","Annotated":399,"Significant":16,"Expected":24.1,"Rank in p.value_classic":4759,"p.value_elim":0.97184,"p.value_classic":0.97262,"genes":"ACOT4,ACSL1,AK1,CTNS,DGAT2,DPYS,GIMAP7,GTPBP1,LRRK2,NPR1,P2RX7,PDE4B,PDK4,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0032434","Term":"regulation of proteasomal ubiquitin-dependent protein catabolic process","Annotated":115,"Significant":3,"Expected":6.95,"Rank in p.value_classic":4760,"p.value_elim":0.97263,"p.value_classic":0.97302,"genes":"DAB2,LRRK2,NUB1"} {"GO.ID":"GO:0072171","Term":"mesonephric tubule morphogenesis","Annotated":58,"Significant":1,"Expected":3.5,"Rank in p.value_classic":4761,"p.value_elim":0.973,"p.value_classic":0.97325,"genes":"AGT"} {"GO.ID":"GO:0009064","Term":"glutamine family amino acid metabolic process","Annotated":58,"Significant":1,"Expected":3.5,"Rank in p.value_classic":4762,"p.value_elim":0.973,"p.value_classic":0.97325,"genes":"GLUL"} {"GO.ID":"GO:0048644","Term":"muscle organ morphogenesis","Annotated":58,"Significant":1,"Expected":3.5,"Rank in p.value_classic":4763,"p.value_elim":0.973,"p.value_classic":0.97325,"genes":"S1PR1"} {"GO.ID":"GO:0043632","Term":"modification-dependent macromolecule catabolic process","Annotated":580,"Significant":25,"Expected":35.03,"Rank in p.value_classic":4768,"p.value_elim":0.97343,"p.value_classic":0.97434,"genes":"ASB2,CCNF,CHMP4C,DAB2,DTL,DTX3L,FBXO6,FEM1C,IFI27,LRRK2,NUB1,PML,PSMB10,PSMB8,PSMB9,PYHIN1,RHOBTB3,RNF19B,RNF213,TBX21,TRIM31,UBD,UBE2L6,UHRF1,WWP1"} {"GO.ID":"GO:0009150","Term":"purine ribonucleotide metabolic process","Annotated":381,"Significant":15,"Expected":23.01,"Rank in p.value_classic":4769,"p.value_elim":0.97365,"p.value_classic":0.97437,"genes":"ACOT4,ACSL1,AK1,CTNS,DGAT2,GIMAP7,GTPBP1,LRRK2,NPR1,P2RX7,PDE4B,PDK4,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:1902679","Term":"negative regulation of RNA biosynthetic process","Annotated":1054,"Significant":50,"Expected":63.66,"Rank in p.value_classic":4772,"p.value_elim":0.97367,"p.value_classic":0.97491,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF3,BCL6,BHLHE41,BIRC5,BRCA1,CD38,CENPF,CIITA,DAB2,E2F1,E2F8,EDN1,ETV7,HESX1,HSBP1L1,IFI27,IRF1,IRF7,KLF4,LBH,MAF,MAFF,MUC1,MYOZ2,NR4A3,OVOL1,PARP10,PARP14,PARP9,PML,RELB,SBNO2,STAT1,TAL1,TBX21,TFEC,TRIM22,UHRF1,WWP1,ZMYND15,ZNF608"} {"GO.ID":"GO:0051258","Term":"protein polymerization","Annotated":255,"Significant":9,"Expected":15.4,"Rank in p.value_classic":4767,"p.value_elim":0.9737,"p.value_classic":0.97428,"genes":"CDH5,FAM107A,JAK2,MSRB1,PSTPIP2,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:0030833","Term":"regulation of actin filament polymerization","Annotated":116,"Significant":3,"Expected":7.01,"Rank in p.value_classic":4764,"p.value_elim":0.9739,"p.value_classic":0.97427,"genes":"SCIN,SPTBN4,TMSB10"} {"GO.ID":"GO:0043467","Term":"regulation of generation of precursor metabolites and energy","Annotated":116,"Significant":3,"Expected":7.01,"Rank in p.value_classic":4765,"p.value_elim":0.9739,"p.value_classic":0.97427,"genes":"CDK1,P2RX7,SLC2A6"} {"GO.ID":"GO:0006413","Term":"translational initiation","Annotated":116,"Significant":3,"Expected":7.01,"Rank in p.value_classic":4766,"p.value_elim":0.9739,"p.value_classic":0.97427,"genes":"BANK1,CCL5,DAZL"} {"GO.ID":"GO:0009152","Term":"purine ribonucleotide biosynthetic process","Annotated":189,"Significant":6,"Expected":11.41,"Rank in p.value_classic":4773,"p.value_elim":0.97448,"p.value_classic":0.97496,"genes":"ACSL1,AK1,NPR1,PDK4,PID1,VPS9D1"} {"GO.ID":"GO:0098930","Term":"axonal transport","Annotated":59,"Significant":1,"Expected":3.56,"Rank in p.value_classic":4770,"p.value_elim":0.97463,"p.value_classic":0.97488,"genes":"DTNBP1"} {"GO.ID":"GO:0051145","Term":"smooth muscle cell differentiation","Annotated":59,"Significant":1,"Expected":3.56,"Rank in p.value_classic":4771,"p.value_elim":0.97463,"p.value_classic":0.97488,"genes":"COMP"} {"GO.ID":"GO:0031110","Term":"regulation of microtubule polymerization or depolymerization","Annotated":90,"Significant":2,"Expected":5.44,"Rank in p.value_classic":4774,"p.value_elim":0.97511,"p.value_classic":0.97541,"genes":"CDH5,STMN1"} {"GO.ID":"GO:0006497","Term":"protein lipidation","Annotated":90,"Significant":2,"Expected":5.44,"Rank in p.value_classic":4775,"p.value_elim":0.97511,"p.value_classic":0.97541,"genes":"GLUL,ZDHHC19"} {"GO.ID":"GO:0046785","Term":"microtubule polymerization","Annotated":90,"Significant":2,"Expected":5.44,"Rank in p.value_classic":4776,"p.value_elim":0.97511,"p.value_classic":0.97541,"genes":"CDH5,STMN1"} {"GO.ID":"GO:0050821","Term":"protein stabilization","Annotated":190,"Significant":6,"Expected":11.48,"Rank in p.value_classic":4777,"p.value_elim":0.97545,"p.value_classic":0.97591,"genes":"ANK2,ATP1B2,PIM1,PYHIN1,SOX17,TESC"} {"GO.ID":"GO:0046034","Term":"ATP metabolic process","Annotated":190,"Significant":6,"Expected":11.48,"Rank in p.value_classic":4778,"p.value_elim":0.97545,"p.value_classic":0.97591,"genes":"AK1,CTNS,P2RX7,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0098876","Term":"vesicle-mediated transport to the plasma membrane","Annotated":143,"Significant":4,"Expected":8.64,"Rank in p.value_classic":4779,"p.value_elim":0.97596,"p.value_classic":0.97635,"genes":"ARL4C,LMTK2,OPTN,VAMP5"} {"GO.ID":"GO:1904888","Term":"cranial skeletal system development","Annotated":60,"Significant":1,"Expected":3.62,"Rank in p.value_classic":4780,"p.value_elim":0.97617,"p.value_classic":0.9764,"genes":"TIFAB"} {"GO.ID":"GO:0140747","Term":"regulation of ncRNA transcription","Annotated":91,"Significant":2,"Expected":5.5,"Rank in p.value_classic":4781,"p.value_elim":0.97639,"p.value_classic":0.97669,"genes":"AGT,KLF4"} {"GO.ID":"GO:0120036","Term":"plasma membrane bounded cell projection organization","Annotated":1282,"Significant":62,"Expected":77.43,"Rank in p.value_classic":4785,"p.value_elim":0.97667,"p.value_classic":0.97792,"genes":"ABLIM3,ANLN,ATP1B2,ATP8B1,B2M,C21orf91,CD38,CDKL1,CIBAR1,CYLD,DAB1,DAB2,DHFR,DNAAF1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FGD5,FSCN1,FSTL4,GHRL,GLDN,GRIN3A,ICAM1,IFT122,IL15RA,JAK2,KCNJ10,KIF26A,KLF4,KREMEN1,LIMK2,LRRC61,LRRK2,LYN,MTSS1,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,P2RX7,PLEK,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S1PR1,SCARF1,SDC2,SEMA6B,SNX10,SPTBN4,STAP1,STMN1,SYNE1,SYT1,TNFRSF21,WEE1"} {"GO.ID":"GO:0033036","Term":"macromolecule localization","Annotated":2549,"Significant":138,"Expected":153.95,"Rank in p.value_classic":4615,"p.value_elim":0.97752,"p.value_classic":0.93769,"genes":"ABCB1,ABCC11,ABCG2,ABLIM3,ACSL1,ADAM8,AGR2,AGT,AMOT,ANK2,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARL4C,ATP13A2,ATP8B1,AURKB,BCL6,BUB1B,C1QTNF5,C3,CADPS2,CCL5,CCNE2,CD38,CD74,CDH5,CDK1,CDS1,CEACAM1,CELSR1,CENPF,CHMP4C,COLQ,COMP,CTNS,CYLD,DAB2,DERL3,DGAT2,DOP1A,DTX3L,DYNLT1,EDN1,EEPD1,EGR2,ESCO2,FCN1,FYB1,GBP1,GBP2,GBP5,GHRL,GLUL,GRAMD1B,GSDMD,HCAR2,HLA-DRB1,IFI27,IFT122,IL12A,IL1RN,ITSN1,JAK2,KPNA5,LAMP3,LAMP5,LIMK2,LMTK2,LPL,LRP5,LRRK2,MAP1LC3C,MCOLN2,MMD,MVP,NCF1,NECAB2,NRCAM,NRP1,OPTN,OSBPL6,P2RX4,P2RX7,PARP3,PARP9,PID1,PLEK,PLSCR1,PLSCR4,PML,PTPRU,PYHIN1,RAB20,RAPGEF2,RBP7,REEP1,RNF213,RSAD2,RTP4,S100A10,S100A13,SCG3,SCIN,SIDT1,SIDT2,SNX10,SNX20,SOAT1,SPTBN4,SRI,STX11,STX1A,SUCNR1,SYNE1,TAP1,TAP2,TESC,TMEM150A,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF11A,TONSL,TRIM17,TRIM22,TRIM69,TSPAN15,TTC39B,VAMP5,VEGFC,XKR6,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0033059","Term":"cellular pigmentation","Annotated":61,"Significant":1,"Expected":3.68,"Rank in p.value_classic":4783,"p.value_elim":0.97761,"p.value_classic":0.97783,"genes":"DTNBP1"} {"GO.ID":"GO:0042147","Term":"retrograde transport, endosome to Golgi","Annotated":92,"Significant":2,"Expected":5.56,"Rank in p.value_classic":4784,"p.value_elim":0.97762,"p.value_classic":0.9779,"genes":"LRRK2,RHOBTB3"} {"GO.ID":"GO:0010256","Term":"endomembrane system organization","Annotated":509,"Significant":29,"Expected":30.74,"Rank in p.value_classic":3540,"p.value_elim":0.97772,"p.value_classic":0.6569,"genes":"ANK2,ANO4,ATP8B1,CASP7,CDK1,CHMP4C,COLEC12,DNM1,DTNBP1,ERC2,F2RL3,LRRK2,MTSS1,MYOF,OPTN,P2RX7,PLSCR1,PLSCR4,PRRT2,REEP1,S100A10,SNX10,STX11,STX1A,SYNE1,SYT1,TRDN,USP6NL,XKR6"} {"GO.ID":"GO:0032386","Term":"regulation of intracellular transport","Annotated":238,"Significant":8,"Expected":14.37,"Rank in p.value_classic":4786,"p.value_elim":0.97787,"p.value_classic":0.97835,"genes":"ATP13A2,CDK1,DAB2,DERL3,IFI27,JAK2,LRRK2,ZC3H12A"} {"GO.ID":"GO:0000902","Term":"cell morphogenesis","Annotated":801,"Significant":36,"Expected":48.38,"Rank in p.value_classic":4789,"p.value_elim":0.97826,"p.value_classic":0.97917,"genes":"ADAM8,BCL6,CCL13,CCL7,CDH5,DAB1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FGD5,FMNL2,FSTL4,HGF,ITGA7,LRATD1,LRRK2,NRCAM,NRN1,NRP1,NYAP2,P2RX7,PLXNA2,PSMB10,RAPGEF2,SDC2,SEMA6B,SIDT2,SOX17,SPTBN4,STMN1,SYNE1,SYT1,TAL1,WEE1"} {"GO.ID":"GO:0009895","Term":"negative regulation of catabolic process","Annotated":304,"Significant":11,"Expected":18.36,"Rank in p.value_classic":4788,"p.value_elim":0.97838,"p.value_classic":0.97891,"genes":"ATP13A2,DAZL,E2F1,HCAR2,HGF,LAMP3,LRRK2,MAD2L1,PDE3B,PML,SLC11A1"} {"GO.ID":"GO:0000956","Term":"nuclear-transcribed mRNA catabolic process","Annotated":120,"Significant":3,"Expected":7.25,"Rank in p.value_classic":4787,"p.value_elim":0.97844,"p.value_classic":0.97876,"genes":"SAMD4A,XRN1,ZC3H12A"} {"GO.ID":"GO:0071705","Term":"nitrogen compound transport","Annotated":1597,"Significant":79,"Expected":96.45,"Rank in p.value_classic":4793,"p.value_elim":0.97872,"p.value_classic":0.98003,"genes":"ABCB1,ABCC11,ABCG2,ADAM8,ADORA3,ANK2,ANKH,APPL2,ARL4C,ATP13A2,ATP8B1,C1QTNF5,CADPS2,CCL5,CD38,CD74,CDK1,CENPF,CHMP4C,COMP,CRHBP,CTNS,DAB2,DERL3,DOP1A,DTNBP1,DTX3L,DYNLT1,EDN1,EGR2,EXOC3L1,FLVCR2,GHRL,GSDMD,HCAR2,HLA-DRB1,IFI27,IL12A,IL1RN,ITSN1,JAK2,KCNJ10,KPNA5,LMTK2,LRP5,LRRK2,LYN,MAP1LC3C,MCOLN2,MVP,OPTN,P2RX7,PLEK,PML,RAB20,RSAD2,S100A13,SERINC5,SIDT1,SIDT2,SLC11A1,SLC16A10,SLC18A1,SLC6A12,SNX10,SNX20,SRI,STX11,STX1A,SUCNR1,SYT1,SYT6,TAP1,TAP2,TESC,TGM2,VAMP5,VEGFC,ZC3H12A"} {"GO.ID":"GO:0051641","Term":"cellular localization","Annotated":2906,"Significant":156,"Expected":175.51,"Rank in p.value_classic":4715,"p.value_elim":0.97894,"p.value_classic":0.96268,"genes":"ABLIM3,ADAM8,AGR2,AMOT,ANK2,ANO4,APPL2,ARL4C,ASIC1,ATP13A2,ATP6V0D2,ATP8B1,AURKB,BCL6,BIRC5,BUB1B,C1QTNF5,CADPS2,CAMK2D,CCL5,CCNE2,CD38,CD74,CDCA5,CDH5,CDK1,CDT1,CEACAM1,CELSR1,CENPF,CHMP4C,COLQ,COMP,CTNS,CXCL10,CXCL11,CXCL9,CYLD,CYSLTR1,DAB2,DERL3,DNM1,DOP1A,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EGR2,EML4,ERC2,ESCO2,F2RL3,FCN1,FYB1,GBP1,GBP2,GBP5,GHRL,GLUL,GRAMD1B,GSDMD,HCAR2,HLA-DRB1,HLA-F,IFI27,IFT122,IGF2R,IL12A,IL1RN,ITSN1,JAK2,KCNJ10,KPNA5,LAMP3,LAMP5,LIMK2,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MAP1LC3C,MCOLN2,MCTP2,MERTK,MMD,MVP,MYOF,NCF1,NDC80,NECAB2,NOD2,NR4A3,NRCAM,NRP1,NUF2,NUSAP1,OPTN,P2RX4,P2RX7,PARP3,PARP9,PID1,PLEK,PML,PRRT2,PTPRU,PYHIN1,RAB20,RAPGEF2,REEP1,REPS2,RHOBTB3,RSAD2,RTP4,S100A10,S100A13,SCG3,SCIN,SCN4B,SIDT2,SLC11A1,SLC18A1,SLC6A12,SNX10,SNX20,SPC24,SPC25,SPTBN4,SRI,STEAP4,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYT1,TAP1,TAP2,TESC,TMEM150A,TMSB10,TNFAIP6,TONSL,TRDN,TRIM17,TRIM22,TRIM69,TSPAN15,TYRO3,VAMP5,VEGFC,ZC3H12A,ZDHHC19,ZWINT"} {"GO.ID":"GO:0006195","Term":"purine nucleotide catabolic process","Annotated":121,"Significant":3,"Expected":7.31,"Rank in p.value_classic":4790,"p.value_elim":0.97945,"p.value_classic":0.97976,"genes":"P2RX7,PDE4B,SLC2A6"} {"GO.ID":"GO:0048592","Term":"eye morphogenesis","Annotated":121,"Significant":3,"Expected":7.31,"Rank in p.value_classic":4791,"p.value_elim":0.97945,"p.value_classic":0.97976,"genes":"DLL1,IFT122,LRP5"} {"GO.ID":"GO:0043487","Term":"regulation of RNA stability","Annotated":171,"Significant":5,"Expected":10.33,"Rank in p.value_classic":4792,"p.value_elim":0.9795,"p.value_classic":0.97987,"genes":"DAZL,E2F1,SAMD4A,SLC11A1,ZC3H12A"} {"GO.ID":"GO:0019693","Term":"ribose phosphate metabolic process","Annotated":411,"Significant":16,"Expected":24.82,"Rank in p.value_classic":4799,"p.value_elim":0.97988,"p.value_classic":0.98047,"genes":"ACOT4,ACSL1,AK1,CTNS,DGAT2,DPYS,GIMAP7,GTPBP1,LRRK2,NPR1,P2RX7,PDE4B,PDK4,PID1,SLC2A6,VPS9D1"} {"GO.ID":"GO:0042158","Term":"lipoprotein biosynthetic process","Annotated":94,"Significant":2,"Expected":5.68,"Rank in p.value_classic":4794,"p.value_elim":0.97988,"p.value_classic":0.98014,"genes":"GLUL,ZDHHC19"} {"GO.ID":"GO:0035303","Term":"regulation of dephosphorylation","Annotated":94,"Significant":2,"Expected":5.68,"Rank in p.value_classic":4795,"p.value_elim":0.97988,"p.value_classic":0.98014,"genes":"CDH5,PLEK"} {"GO.ID":"GO:0001841","Term":"neural tube formation","Annotated":94,"Significant":2,"Expected":5.68,"Rank in p.value_classic":4796,"p.value_elim":0.97988,"p.value_classic":0.98014,"genes":"CELSR1,IFT122"} {"GO.ID":"GO:0006754","Term":"ATP biosynthetic process","Annotated":94,"Significant":2,"Expected":5.68,"Rank in p.value_classic":4797,"p.value_elim":0.97988,"p.value_classic":0.98014,"genes":"PID1,VPS9D1"} {"GO.ID":"GO:0000288","Term":"nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","Annotated":63,"Significant":1,"Expected":3.8,"Rank in p.value_classic":4798,"p.value_elim":0.98024,"p.value_classic":0.98044,"genes":"SAMD4A"} {"GO.ID":"GO:0072175","Term":"epithelial tube formation","Annotated":122,"Significant":3,"Expected":7.37,"Rank in p.value_classic":4800,"p.value_elim":0.98041,"p.value_classic":0.98071,"genes":"CELSR1,HESX1,IFT122"} {"GO.ID":"GO:0031109","Term":"microtubule polymerization or depolymerization","Annotated":123,"Significant":3,"Expected":7.43,"Rank in p.value_classic":4801,"p.value_elim":0.98134,"p.value_classic":0.98162,"genes":"CDH5,KIF18B,STMN1"} {"GO.ID":"GO:0006414","Term":"translational elongation","Annotated":64,"Significant":1,"Expected":3.87,"Rank in p.value_classic":4802,"p.value_elim":0.98143,"p.value_classic":0.98163,"genes":"GTPBP1"} {"GO.ID":"GO:0030030","Term":"cell projection organization","Annotated":1317,"Significant":63,"Expected":79.54,"Rank in p.value_classic":4805,"p.value_elim":0.98249,"p.value_classic":0.98348,"genes":"ABLIM3,ANLN,ATP1B2,ATP8B1,B2M,C21orf91,CD38,CDKL1,CIBAR1,CYLD,DAB1,DAB2,DHFR,DNAAF1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FGD5,FSCN1,FSTL4,GHRL,GLDN,GRIN3A,ICAM1,IFT122,IL15RA,JAK2,KCNJ10,KIF26A,KLF4,KREMEN1,LIMK2,LRRC61,LRRK2,LYN,MTSS1,NRCAM,NRN1,NRP1,NYAP2,OLIG1,ONECUT2,P2RX7,PLEK,PLXNA2,RAPGEF2,RASGRF1,RTN4RL1,S1PR1,SCARF1,SCIN,SDC2,SEMA6B,SNX10,SPTBN4,STAP1,STMN1,SYNE1,SYT1,TNFRSF21,WEE1"} {"GO.ID":"GO:0009247","Term":"glycolipid biosynthetic process","Annotated":65,"Significant":1,"Expected":3.93,"Rank in p.value_classic":4803,"p.value_elim":0.98256,"p.value_classic":0.98274,"genes":"GAL3ST4"} {"GO.ID":"GO:0006643","Term":"membrane lipid metabolic process","Annotated":175,"Significant":5,"Expected":10.57,"Rank in p.value_classic":4804,"p.value_elim":0.98265,"p.value_classic":0.98298,"genes":"ENPP2,GAL3ST4,NAAA,P2RX7,SGPL1"} {"GO.ID":"GO:0060271","Term":"cilium assembly","Annotated":312,"Significant":11,"Expected":18.84,"Rank in p.value_classic":4808,"p.value_elim":0.98334,"p.value_classic":0.98377,"genes":"ABLIM3,CDKL1,CIBAR1,CYLD,DNAAF1,IFT122,KCNJ10,LIMK2,LRRC61,ONECUT2,SNX10"} {"GO.ID":"GO:0006487","Term":"protein N-linked glycosylation","Annotated":66,"Significant":1,"Expected":3.99,"Rank in p.value_classic":4809,"p.value_elim":0.98361,"p.value_classic":0.98379,"genes":"DERL3"} {"GO.ID":"GO:0035195","Term":"miRNA-mediated post-transcriptional gene silencing","Annotated":66,"Significant":1,"Expected":3.99,"Rank in p.value_classic":4810,"p.value_elim":0.98361,"p.value_classic":0.98379,"genes":"MIR503"} {"GO.ID":"GO:0097722","Term":"sperm motility","Annotated":66,"Significant":1,"Expected":3.99,"Rank in p.value_classic":4811,"p.value_elim":0.98361,"p.value_classic":0.98379,"genes":"SEPTIN4"} {"GO.ID":"GO:0030317","Term":"flagellated sperm motility","Annotated":66,"Significant":1,"Expected":3.99,"Rank in p.value_classic":4812,"p.value_elim":0.98361,"p.value_classic":0.98379,"genes":"SEPTIN4"} {"GO.ID":"GO:0061157","Term":"mRNA destabilization","Annotated":98,"Significant":2,"Expected":5.92,"Rank in p.value_classic":4813,"p.value_elim":0.98376,"p.value_classic":0.98398,"genes":"SAMD4A,ZC3H12A"} {"GO.ID":"GO:0071824","Term":"protein-DNA complex organization","Annotated":758,"Significant":33,"Expected":45.78,"Rank in p.value_classic":4816,"p.value_elim":0.98418,"p.value_classic":0.98485,"genes":"BAZ1A,BCL6,BRCA1,CDC45,CDK1,CDT1,CENPF,CENPK,CHAF1B,DMC1,DTX3L,EPOP,ERCC6L,H2BC21,HELLS,HJURP,IRF4,JADE2,JAK2,MCM2,MKI67,NPM2,OIP5,PADI2,PARP10,RAD54B,RAD54L,TAL1,TDRD9,TGM2,TONSL,UHRF1,ZNFX1"} {"GO.ID":"GO:1904377","Term":"positive regulation of protein localization to cell periphery","Annotated":67,"Significant":1,"Expected":4.05,"Rank in p.value_classic":4814,"p.value_elim":0.98461,"p.value_classic":0.98477,"genes":"AGR2"} {"GO.ID":"GO:0006626","Term":"protein targeting to mitochondrion","Annotated":99,"Significant":2,"Expected":5.98,"Rank in p.value_classic":4815,"p.value_elim":0.98461,"p.value_classic":0.98482,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0044242","Term":"cellular lipid catabolic process","Annotated":178,"Significant":5,"Expected":10.75,"Rank in p.value_classic":4817,"p.value_elim":0.98472,"p.value_classic":0.98501,"genes":"ENPP2,LPL,PLB1,PNPLA3,SGPL1"} {"GO.ID":"GO:0009260","Term":"ribonucleotide biosynthetic process","Annotated":202,"Significant":6,"Expected":12.2,"Rank in p.value_classic":4818,"p.value_elim":0.98472,"p.value_classic":0.98504,"genes":"ACSL1,AK1,NPR1,PDK4,PID1,VPS9D1"} {"GO.ID":"GO:0051648","Term":"vesicle localization","Annotated":203,"Significant":6,"Expected":12.26,"Rank in p.value_classic":4820,"p.value_elim":0.98532,"p.value_classic":0.98563,"genes":"ATP13A2,CADPS2,DNM1,DTNBP1,LIMK2,LRRK2"} {"GO.ID":"GO:2000779","Term":"regulation of double-strand break repair","Annotated":128,"Significant":3,"Expected":7.73,"Rank in p.value_classic":4819,"p.value_elim":0.98536,"p.value_classic":0.98559,"genes":"PARP3,PML,RMI2"} {"GO.ID":"GO:0009056","Term":"catabolic process","Annotated":2205,"Significant":115,"Expected":133.17,"Rank in p.value_classic":4745,"p.value_elim":0.98585,"p.value_classic":0.96818,"genes":"ACOT4,ACSL1,ADAM8,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,ASB2,ATP13A2,ATP6V0D2,CALCOCO2,CASP7,CBR3,CCNF,CEACAM1,CHAC1,CHMP4C,COLQ,CTRL,CTSL,CTSO,CTSS,CYP1A1,DAB2,DAZL,DEPTOR,DERL3,DPYS,DRAM1,DTL,DTX3L,E2F1,ENPP2,ENPP4,EPHX1,ERAP2,FBXO6,FEM1C,FEN1,G6PC1,GGT5,GK,GLUL,GTPBP1,HCAR2,HGF,HSD11B1,IDO1,IDO2,IFI27,IL4I1,ISG20,LAMP3,LPL,LRP5,LRRK2,LYVE1,MAD2L1,MAP1LC3C,MEFV,MMP25,MMP9,NAAA,NOD2,NUB1,OAS2,OPTN,P2RX7,PDE3B,PDE4B,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PMAIP1,PML,PNPLA3,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RALB,RHOBTB3,RIPK2,RNF19B,RNF213,RUFY4,SAMD4A,SAT1,SCARF1,SESN3,SGPL1,SIDT2,SLC11A1,SLC2A6,SOX17,TBX21,TMEM150A,TPCN1,TRIM17,TRIM22,TRIM31,TSPAN15,TYMP,UBD,UBE2L6,UHRF1,UNG,WWP1,XRN1,ZC3H12A"} {"GO.ID":"GO:0032271","Term":"regulation of protein polymerization","Annotated":180,"Significant":5,"Expected":10.87,"Rank in p.value_classic":4821,"p.value_elim":0.98596,"p.value_classic":0.98624,"genes":"CDH5,SCIN,SPTBN4,STMN1,TMSB10"} {"GO.ID":"GO:1903313","Term":"positive regulation of mRNA metabolic process","Annotated":129,"Significant":3,"Expected":7.79,"Rank in p.value_classic":4822,"p.value_elim":0.98606,"p.value_classic":0.98628,"genes":"GTPBP1,SAMD4A,ZC3H12A"} {"GO.ID":"GO:0003341","Term":"cilium movement","Annotated":101,"Significant":2,"Expected":6.1,"Rank in p.value_classic":4823,"p.value_elim":0.98618,"p.value_classic":0.98638,"genes":"DNAAF1,SEPTIN4"} {"GO.ID":"GO:0010569","Term":"regulation of double-strand break repair via homologous recombination","Annotated":69,"Significant":1,"Expected":4.17,"Rank in p.value_classic":4824,"p.value_elim":0.98641,"p.value_classic":0.98657,"genes":"RMI2"} {"GO.ID":"GO:0008088","Term":"axo-dendritic transport","Annotated":69,"Significant":1,"Expected":4.17,"Rank in p.value_classic":4825,"p.value_elim":0.98641,"p.value_classic":0.98657,"genes":"DTNBP1"} {"GO.ID":"GO:0061077","Term":"chaperone-mediated protein folding","Annotated":69,"Significant":1,"Expected":4.17,"Rank in p.value_classic":4826,"p.value_elim":0.98641,"p.value_classic":0.98657,"genes":"CD74"} {"GO.ID":"GO:0016482","Term":"cytosolic transport","Annotated":130,"Significant":3,"Expected":7.85,"Rank in p.value_classic":4827,"p.value_elim":0.98672,"p.value_classic":0.98694,"genes":"DOP1A,LRRK2,RHOBTB3"} {"GO.ID":"GO:0009206","Term":"purine ribonucleoside triphosphate biosynthetic process","Annotated":102,"Significant":2,"Expected":6.16,"Rank in p.value_classic":4828,"p.value_elim":0.98691,"p.value_classic":0.98709,"genes":"PID1,VPS9D1"} {"GO.ID":"GO:0050779","Term":"RNA destabilization","Annotated":102,"Significant":2,"Expected":6.16,"Rank in p.value_classic":4829,"p.value_elim":0.98691,"p.value_classic":0.98709,"genes":"SAMD4A,ZC3H12A"} {"GO.ID":"GO:0003206","Term":"cardiac chamber morphogenesis","Annotated":102,"Significant":2,"Expected":6.16,"Rank in p.value_classic":4830,"p.value_elim":0.98691,"p.value_classic":0.98709,"genes":"DHRS3,NRP1"} {"GO.ID":"GO:0001942","Term":"hair follicle development","Annotated":70,"Significant":1,"Expected":4.23,"Rank in p.value_classic":4831,"p.value_elim":0.98724,"p.value_classic":0.98738,"genes":"EDA"} {"GO.ID":"GO:1901137","Term":"carbohydrate derivative biosynthetic process","Annotated":590,"Significant":24,"Expected":35.63,"Rank in p.value_classic":4833,"p.value_elim":0.98724,"p.value_classic":0.98773,"genes":"ACSL1,AK1,CMPK2,DERL3,DSE,GAL3ST4,GALNT18,GCNT3,GK,HBEGF,IL15,JAK3,NECAB2,NPR1,PDK4,PID1,PRTFDC1,RRM2,SOAT1,TK1,TMTC1,TYMS,VPS9D1,XYLT1"} {"GO.ID":"GO:0016331","Term":"morphogenesis of embryonic epithelium","Annotated":131,"Significant":3,"Expected":7.91,"Rank in p.value_classic":4832,"p.value_elim":0.98736,"p.value_classic":0.98757,"genes":"CELSR1,IFT122,VEGFC"} {"GO.ID":"GO:0036211","Term":"protein modification process","Annotated":2528,"Significant":144,"Expected":152.68,"Rank in p.value_classic":4103,"p.value_elim":0.98743,"p.value_classic":0.80259,"genes":"AATK,AGT,AMER1,ASB2,ATP13A2,AURKB,BANK1,BIRC5,BRCA1,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDCA3,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CISH,CLEC6A,CLSPN,CSF1,CX3CR1,CYLD,DAB2,DAPP1,DEPTOR,DERL3,DSCC1,DTL,DTNBP1,DTX3L,EDN1,EGR2,ENPP2,EPAS1,EPHB3,ESCO2,FAM107A,FAM20A,FAS,FAXDC2,FBXO6,FEM1C,GALNT18,GCNT3,GLUL,HBEGF,HGF,HLA-DRB1,IFI27,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JADE2,JAK2,JAK3,KITLG,LIMK2,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MEFV,MERTK,MMD,MMP9,MVP,NCF1,NLRP12,NMI,NOD2,NRP1,NUB1,OSM,OTUD1,P2RX7,PARP10,PARP12,PARP14,PARP3,PARP9,PDK4,PID1,PIM1,PKIB,PKMYT1,PML,PPM1E,PRKX,PTPRU,RALB,RAPGEF2,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SLC11A1,SOCS1,SPTBN4,STAMBPL1,STAT2,STX1A,TANK,TGM2,TLR7,TLR8,TMEM119,TMTC1,TNFRSF11A,TNFRSF14,TNFSF18,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,VEGFC,VRK2,WARS1,WEE1,WWP1,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0009145","Term":"purine nucleoside triphosphate biosynthetic process","Annotated":103,"Significant":2,"Expected":6.22,"Rank in p.value_classic":4834,"p.value_elim":0.9876,"p.value_classic":0.98778,"genes":"PID1,VPS9D1"} {"GO.ID":"GO:0006402","Term":"mRNA catabolic process","Annotated":231,"Significant":7,"Expected":13.95,"Rank in p.value_classic":4835,"p.value_elim":0.98771,"p.value_classic":0.98799,"genes":"DAZL,E2F1,GTPBP1,SAMD4A,SLC11A1,XRN1,ZC3H12A"} {"GO.ID":"GO:0072657","Term":"protein localization to membrane","Annotated":531,"Significant":21,"Expected":32.07,"Rank in p.value_classic":4836,"p.value_elim":0.98774,"p.value_classic":0.98818,"genes":"AGR2,ANK2,COLQ,DAB2,FYB1,GBP1,NCF1,NECAB2,OPTN,PID1,RAPGEF2,REEP1,RTP4,S100A10,SPTBN4,TESC,TMEM150A,TNFAIP6,TSPAN15,VAMP5,ZDHHC19"} {"GO.ID":"GO:0046390","Term":"ribose phosphate biosynthetic process","Annotated":208,"Significant":6,"Expected":12.56,"Rank in p.value_classic":4837,"p.value_elim":0.98802,"p.value_classic":0.98827,"genes":"ACSL1,AK1,NPR1,PDK4,PID1,VPS9D1"} {"GO.ID":"GO:0048519","Term":"negative regulation of biological process","Annotated":4321,"Significant":301,"Expected":260.97,"Rank in p.value_classic":499,"p.value_elim":0.9884,"p.value_classic":0.00113,"genes":"ACOD1,ADAM8,ADORA3,AGT,AIFM2,AIM2,AMER1,AMOT,ANK2,ANTXR1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF3,BAZ1A,BCL2A1,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,BUB1B,CAMK2D,CARD16,CASTOR1,CCL5,CCL8,CCNF,CD274,CD28,CD300LF,CD38,CD74,CD80,CD83,CDC45,CDC6,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHMP4C,CHRD,CIITA,CISH,CLSPN,COMP,CR1L,CRHBP,CTLA4,CTNS,CX3CR1,CXCL10,CXCL11,CXCL9,CYLD,DAB1,DAB2,DAZL,DEPTOR,DERL3,DHFR,DHRS3,DKK2,DLL1,DTL,DTNBP1,DTX3L,DYNLT1,DYSF,E2F1,E2F2,E2F8,EDN1,EME1,ETV7,F2RL3,FAM107A,FAS,FBXO6,FCN1,FGL1,FGL2,FSTL4,GBP1,GBP7,GCH1,GHRL,GJD3,GPR31,GRAMD4,GRIN3A,GTPBP1,GTSE1,HBEGF,HCAR2,HELLS,HESX1,HGF,HLA-A,HLA-B,HLA-DOA,HLA-DOB,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HTRA1,ICAM1,IDO1,IFI27,IFI35,IFIH1,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IL12A,IL15,IL15RA,IL1RN,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KCNE5,KIF26A,KITLG,KLF4,KLRK1,KREMEN1,LAG3,LAMP3,LBH,LILRA2,LILRB3,LIMK2,LITAF,LRP5,LRRK2,LTA,LYN,MAD2L1,MAF,MAFF,MEFV,MERTK,MIR503,MMP9,MT2A,MTSS1,MUC1,MVP,MYOZ2,NDC80,NECAB2,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,NRP1,NUF2,OAS2,OAS3,ONECUT2,OPTN,ORC1,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCDHGC3,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLAAT4,PLEK,PLSCR1,PLXNA2,PML,PPM1E,PROK2,PRRT2,PTGER4,PTPRU,RAPGEF2,RELB,RGS18,RMI2,RNF213,RSAD2,RTN4RL1,S1PR1,SAMD4A,SBNO2,SCIN,SEMA6B,SERPING1,SESN3,SLAMF1,SLAMF8,SLC11A1,SOCS1,SOX17,SPC24,SPC25,SPTBN4,SRI,SSTR2,STAP1,STAT1,STAT2,STMN1,SYNE1,TAL1,TANK,TAPBPL,TBX21,TDRD9,TESC,TFEC,THBD,THBS2,TICRR,TIFAB,TLR8,TMEM109,TMEM119,TMEM176A,TMEM176B,TMSB10,TNFAIP6,TNFRSF14,TNFRSF21,TNFSF18,TOP2A,TRABD2A,TRAFD1,TRDN,TRIM22,TRIM31,TSPAN15,TSPAN32,TTC39B,TYMS,TYRO3,UHRF1,UNG,VEGFC,WARS1,WDR76,WEE1,WWP1,XAF1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1,ZWINT"} {"GO.ID":"GO:0022404","Term":"molting cycle process","Annotated":72,"Significant":1,"Expected":4.35,"Rank in p.value_classic":4838,"p.value_elim":0.98874,"p.value_classic":0.98887,"genes":"EDA"} {"GO.ID":"GO:0022405","Term":"hair cycle process","Annotated":72,"Significant":1,"Expected":4.35,"Rank in p.value_classic":4839,"p.value_elim":0.98874,"p.value_classic":0.98887,"genes":"EDA"} {"GO.ID":"GO:0035304","Term":"regulation of protein dephosphorylation","Annotated":72,"Significant":1,"Expected":4.35,"Rank in p.value_classic":4840,"p.value_elim":0.98874,"p.value_classic":0.98887,"genes":"CDH5"} {"GO.ID":"GO:0099072","Term":"regulation of postsynaptic membrane neurotransmitter receptor levels","Annotated":72,"Significant":1,"Expected":4.35,"Rank in p.value_classic":4841,"p.value_elim":0.98874,"p.value_classic":0.98887,"genes":"SYNE1"} {"GO.ID":"GO:0045892","Term":"negative regulation of DNA-templated transcription","Annotated":1042,"Significant":47,"Expected":62.93,"Rank in p.value_classic":4843,"p.value_elim":0.98878,"p.value_classic":0.98937,"genes":"ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF3,BCL6,BHLHE41,BIRC5,BRCA1,CD38,CENPF,CIITA,DAB2,E2F1,E2F8,EDN1,ETV7,HESX1,HSBP1L1,IFI27,IRF1,IRF7,KLF4,LBH,MAF,MAFF,MUC1,MYOZ2,NR4A3,OVOL1,PARP10,PARP14,PARP9,PML,RELB,SBNO2,STAT1,TAL1,TBX21,TFEC,TRIM22,UHRF1,WWP1,ZMYND15,ZNF608"} {"GO.ID":"GO:0015931","Term":"nucleobase-containing compound transport","Annotated":210,"Significant":6,"Expected":12.68,"Rank in p.value_classic":4842,"p.value_elim":0.98896,"p.value_classic":0.9892,"genes":"ABCC11,ANKH,MVP,P2RX7,SIDT1,SIDT2"} {"GO.ID":"GO:0006325","Term":"chromatin organization","Annotated":676,"Significant":28,"Expected":40.83,"Rank in p.value_classic":4845,"p.value_elim":0.98912,"p.value_classic":0.98957,"genes":"BAZ1A,BCL6,BRCA1,CDK1,CHAF1B,DTX3L,EPOP,ERCC6L,H2BC21,HELLS,HJURP,IRF4,JADE2,JAK2,MCM2,MKI67,NPM2,OIP5,PADI2,PARP10,RAD54B,RAD54L,TAL1,TDRD9,TGM2,TONSL,UHRF1,ZNFX1"} {"GO.ID":"GO:0007018","Term":"microtubule-based movement","Annotated":303,"Significant":10,"Expected":18.3,"Rank in p.value_classic":4844,"p.value_elim":0.98928,"p.value_classic":0.98957,"genes":"DNAAF1,DTNBP1,DYNLT1,DYNLT5,IFT122,KIF11,KIF15,KIF18B,KIF23,SEPTIN4"} {"GO.ID":"GO:0005975","Term":"carbohydrate metabolic process","Annotated":454,"Significant":17,"Expected":27.42,"Rank in p.value_classic":4846,"p.value_elim":0.98946,"p.value_classic":0.98981,"genes":"ATF3,DGAT2,G6PC1,GAL3ST4,GCNT3,GHRL,GK,LRP5,MGAM2,P2RX7,PCDH12,PDK4,PLEK,PMAIP1,SLC2A5,SLC2A6,SLC45A3"} {"GO.ID":"GO:0015986","Term":"proton motive force-driven ATP synthesis","Annotated":74,"Significant":1,"Expected":4.47,"Rank in p.value_classic":4848,"p.value_elim":0.99006,"p.value_classic":0.99018,"genes":"VPS9D1"} {"GO.ID":"GO:0120039","Term":"plasma membrane bounded cell projection morphogenesis","Annotated":540,"Significant":21,"Expected":32.61,"Rank in p.value_classic":4851,"p.value_elim":0.99042,"p.value_classic":0.99078,"genes":"DAB1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FSTL4,LRRK2,NRCAM,NRN1,NRP1,NYAP2,PLXNA2,RAPGEF2,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1,SYT1,WEE1"} {"GO.ID":"GO:0009201","Term":"ribonucleoside triphosphate biosynthetic process","Annotated":108,"Significant":2,"Expected":6.52,"Rank in p.value_classic":4849,"p.value_elim":0.99055,"p.value_classic":0.99069,"genes":"PID1,VPS9D1"} {"GO.ID":"GO:0036503","Term":"ERAD pathway","Annotated":108,"Significant":2,"Expected":6.52,"Rank in p.value_classic":4850,"p.value_elim":0.99055,"p.value_classic":0.99069,"genes":"DERL3,FBXO6"} {"GO.ID":"GO:0051052","Term":"regulation of DNA metabolic process","Annotated":476,"Significant":32,"Expected":28.75,"Rank in p.value_classic":2185,"p.value_elim":0.99064,"p.value_classic":0.28837,"genes":"AURKB,BAZ1A,BCL6,BRCA1,CCNA2,CD28,CDC25A,CDC6,CDK1,CDT1,CHTF18,DSCC1,E2F8,ESCO2,GCH1,HGF,JADE2,KLF4,MCM2,MCM4,MCM5,MCM6,MCM7,NPM2,PARP3,PKIB,PML,RMI2,TBX21,TICRR,WEE1,XRN1"} {"GO.ID":"GO:0009894","Term":"regulation of catabolic process","Annotated":918,"Significant":40,"Expected":55.44,"Rank in p.value_classic":4855,"p.value_elim":0.99089,"p.value_classic":0.99135,"genes":"ADAM8,AMER1,ATP13A2,ATP6V0D2,CALCOCO2,DAB2,DAZL,DEPTOR,DRAM1,DTL,DTX3L,E2F1,GTPBP1,HCAR2,HGF,LAMP3,LRRK2,MAD2L1,MEFV,NOD2,NUB1,OPTN,P2RX7,PDE3B,PML,PSME1,PSME2,PYHIN1,RALB,RIPK2,RUFY4,SAMD4A,SESN3,SLC11A1,SLC2A6,SOX17,TPCN1,TRIM22,TSPAN15,ZC3H12A"} {"GO.ID":"GO:0045934","Term":"negative regulation of nucleobase-containing compound metabolic process","Annotated":1260,"Significant":58,"Expected":76.1,"Rank in p.value_classic":4856,"p.value_elim":0.99095,"p.value_classic":0.99149,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF3,BCL6,BHLHE41,BIRC5,BRCA1,CD38,CDC6,CDT1,CENPF,CIITA,DAB2,DAZL,E2F1,E2F8,EDN1,ETV7,HESX1,HSBP1L1,IFI27,IRF1,IRF7,KLF4,LBH,MAF,MAFF,MUC1,MYOZ2,NR4A3,OVOL1,PARP10,PARP14,PARP3,PARP9,PID1,PML,RELB,RMI2,SBNO2,SLC11A1,STAT1,TAL1,TBX21,TFEC,TRIM22,UHRF1,WWP1,XRN1,ZMYND15,ZNF608"} {"GO.ID":"GO:0031346","Term":"positive regulation of cell projection organization","Annotated":308,"Significant":10,"Expected":18.6,"Rank in p.value_classic":4853,"p.value_elim":0.99102,"p.value_classic":0.99126,"genes":"ANLN,ATP1B2,ENPP2,FSCN1,LYN,NRP1,P2RX7,PLXNA2,RAPGEF2,SCARF1"} {"GO.ID":"GO:0060294","Term":"cilium movement involved in cell motility","Annotated":76,"Significant":1,"Expected":4.59,"Rank in p.value_classic":4854,"p.value_elim":0.99123,"p.value_classic":0.99134,"genes":"SEPTIN4"} {"GO.ID":"GO:0048858","Term":"cell projection morphogenesis","Annotated":544,"Significant":21,"Expected":32.86,"Rank in p.value_classic":4858,"p.value_elim":0.99143,"p.value_classic":0.99175,"genes":"DAB1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FSTL4,LRRK2,NRCAM,NRN1,NRP1,NYAP2,PLXNA2,RAPGEF2,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1,SYT1,WEE1"} {"GO.ID":"GO:0003205","Term":"cardiac chamber development","Annotated":139,"Significant":3,"Expected":8.39,"Rank in p.value_classic":4857,"p.value_elim":0.99149,"p.value_classic":0.99164,"genes":"ANK2,DHRS3,NRP1"} {"GO.ID":"GO:0015031","Term":"protein transport","Annotated":1245,"Significant":57,"Expected":75.19,"Rank in p.value_classic":4860,"p.value_elim":0.99159,"p.value_classic":0.9921,"genes":"ADAM8,ANK2,APPL2,ARL4C,ATP13A2,C1QTNF5,CADPS2,CCL5,CD38,CD74,CDK1,CENPF,CHMP4C,COMP,CTNS,DAB2,DERL3,DOP1A,DTX3L,DYNLT1,EGR2,GHRL,GSDMD,HCAR2,HLA-DRB1,IFI27,IL12A,IL1RN,ITSN1,JAK2,KPNA5,LMTK2,LRP5,LRRK2,MAP1LC3C,MCOLN2,MVP,OPTN,P2RX7,PLEK,PML,RAB20,RSAD2,S100A13,SIDT2,SNX10,SNX20,SRI,STX11,STX1A,SUCNR1,TAP1,TAP2,TESC,VAMP5,VEGFC,ZC3H12A"} {"GO.ID":"GO:0008104","Term":"protein localization","Annotated":2179,"Significant":108,"Expected":131.6,"Rank in p.value_classic":4863,"p.value_elim":0.99161,"p.value_classic":0.99231,"genes":"ABLIM3,ADAM8,AGR2,AMOT,ANK2,APPL2,ARL4C,ATP13A2,ATP8B1,AURKB,BCL6,BUB1B,C1QTNF5,CADPS2,CCL5,CCNE2,CD38,CD74,CDH5,CDK1,CELSR1,CENPF,CHMP4C,COLQ,COMP,CTNS,CYLD,DAB2,DERL3,DOP1A,DTX3L,DYNLT1,EDN1,EGR2,ESCO2,FCN1,FYB1,GBP1,GBP2,GBP5,GHRL,GLUL,GSDMD,HCAR2,HLA-DRB1,IFI27,IFT122,IL12A,IL1RN,ITSN1,JAK2,KPNA5,LAMP3,LAMP5,LIMK2,LMTK2,LRP5,LRRK2,MAP1LC3C,MCOLN2,MMD,MVP,NCF1,NECAB2,NRCAM,NRP1,OPTN,P2RX7,PARP3,PARP9,PID1,PLEK,PML,PTPRU,PYHIN1,RAB20,RAPGEF2,REEP1,RSAD2,RTP4,S100A10,S100A13,SCG3,SCIN,SIDT2,SNX10,SNX20,SPTBN4,SRI,STX11,STX1A,SUCNR1,SYNE1,TAP1,TAP2,TESC,TMEM150A,TMSB10,TNFAIP6,TONSL,TRIM17,TRIM22,TRIM69,TSPAN15,VAMP5,VEGFC,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0031330","Term":"negative regulation of cellular catabolic process","Annotated":192,"Significant":5,"Expected":11.6,"Rank in p.value_classic":4859,"p.value_elim":0.99164,"p.value_classic":0.99182,"genes":"DAZL,E2F1,HGF,LRRK2,SLC11A1"} {"GO.ID":"GO:0048812","Term":"neuron projection morphogenesis","Annotated":525,"Significant":20,"Expected":31.71,"Rank in p.value_classic":4862,"p.value_elim":0.99181,"p.value_classic":0.99211,"genes":"DAB1,DTNBP1,EDN1,EGR2,EPHB3,FSTL4,LRRK2,NRCAM,NRN1,NRP1,NYAP2,PLXNA2,RAPGEF2,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1,SYT1,WEE1"} {"GO.ID":"GO:0001838","Term":"embryonic epithelial tube formation","Annotated":111,"Significant":2,"Expected":6.7,"Rank in p.value_classic":4861,"p.value_elim":0.99198,"p.value_classic":0.9921,"genes":"CELSR1,IFT122"} {"GO.ID":"GO:0044782","Term":"cilium organization","Annotated":334,"Significant":11,"Expected":20.17,"Rank in p.value_classic":4864,"p.value_elim":0.9921,"p.value_classic":0.99233,"genes":"ABLIM3,CDKL1,CIBAR1,CYLD,DNAAF1,IFT122,KCNJ10,LIMK2,LRRC61,ONECUT2,SNX10"} {"GO.ID":"GO:0031647","Term":"regulation of protein stability","Annotated":289,"Significant":9,"Expected":17.45,"Rank in p.value_classic":4865,"p.value_elim":0.99214,"p.value_classic":0.99235,"genes":"ANK2,ATP1B2,FAM107A,LRRK2,NDC80,PIM1,PYHIN1,SOX17,TESC"} {"GO.ID":"GO:0035194","Term":"regulatory ncRNA-mediated post-transcriptional gene silencing","Annotated":78,"Significant":1,"Expected":4.71,"Rank in p.value_classic":4866,"p.value_elim":0.99226,"p.value_classic":0.99236,"genes":"MIR503"} {"GO.ID":"GO:0051253","Term":"negative regulation of RNA metabolic process","Annotated":1156,"Significant":52,"Expected":69.82,"Rank in p.value_classic":4871,"p.value_elim":0.99244,"p.value_classic":0.99288,"genes":"APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF3,BCL6,BHLHE41,BIRC5,BRCA1,CD38,CENPF,CIITA,DAB2,DAZL,E2F1,E2F8,EDN1,ETV7,HESX1,HSBP1L1,IFI27,IRF1,IRF7,KLF4,LBH,MAF,MAFF,MUC1,MYOZ2,NR4A3,OVOL1,PARP10,PARP14,PARP9,PML,RELB,SBNO2,SLC11A1,STAT1,TAL1,TBX21,TFEC,TRIM22,UHRF1,WWP1,ZMYND15,ZNF608"} {"GO.ID":"GO:0051172","Term":"negative regulation of nitrogen compound metabolic process","Annotated":1825,"Significant":88,"Expected":110.22,"Rank in p.value_classic":4874,"p.value_elim":0.99262,"p.value_classic":0.99318,"genes":"AGT,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,BACH1,BANK1,BATF3,BCL6,BHLHE41,BIRC5,BRCA1,CARD16,CD38,CDC6,CDT1,CEACAM1,CENPF,CHAC1,CIITA,DAB2,DAZL,DEPTOR,DHFR,DTNBP1,DTX3L,E2F1,E2F8,EDN1,ETV7,HBEGF,HESX1,HGF,HSBP1L1,IFI27,IRF1,IRF7,JAK3,KLF4,LAMP3,LBH,LRP5,LRRK2,LYN,MAD2L1,MAF,MAFF,MIR503,MMP9,MUC1,MVP,MYOZ2,NLRP12,NR4A3,OVOL1,PARP10,PARP14,PARP3,PARP9,PID1,PKIB,PML,PPM1E,RELB,RMI2,SAMD4A,SBNO2,SERPING1,SLC11A1,SOCS1,STAT1,TAL1,TBX21,TFEC,TRIM22,TYMS,UHRF1,WARS1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF608"} {"GO.ID":"GO:0016054","Term":"organic acid catabolic process","Annotated":195,"Significant":5,"Expected":11.78,"Rank in p.value_classic":4869,"p.value_elim":0.99267,"p.value_classic":0.99283,"genes":"ACOT4,GLUL,IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0046395","Term":"carboxylic acid catabolic process","Annotated":195,"Significant":5,"Expected":11.78,"Rank in p.value_classic":4870,"p.value_elim":0.99267,"p.value_classic":0.99283,"genes":"ACOT4,GLUL,IDO1,IDO2,IL4I1"} {"GO.ID":"GO:0060285","Term":"cilium-dependent cell motility","Annotated":79,"Significant":1,"Expected":4.77,"Rank in p.value_classic":4867,"p.value_elim":0.99273,"p.value_classic":0.99282,"genes":"SEPTIN4"} {"GO.ID":"GO:0001539","Term":"cilium or flagellum-dependent cell motility","Annotated":79,"Significant":1,"Expected":4.77,"Rank in p.value_classic":4868,"p.value_elim":0.99273,"p.value_classic":0.99282,"genes":"SEPTIN4"} {"GO.ID":"GO:0072655","Term":"establishment of protein localization to mitochondrion","Annotated":113,"Significant":2,"Expected":6.82,"Rank in p.value_classic":4872,"p.value_elim":0.99281,"p.value_classic":0.99292,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0007612","Term":"learning","Annotated":113,"Significant":2,"Expected":6.82,"Rank in p.value_classic":4873,"p.value_elim":0.99281,"p.value_classic":0.99292,"genes":"ASIC1,CTNS"} {"GO.ID":"GO:0070727","Term":"cellular macromolecule localization","Annotated":2189,"Significant":108,"Expected":132.21,"Rank in p.value_classic":4876,"p.value_elim":0.99284,"p.value_classic":0.99345,"genes":"ABLIM3,ADAM8,AGR2,AMOT,ANK2,APPL2,ARL4C,ATP13A2,ATP8B1,AURKB,BCL6,BUB1B,C1QTNF5,CADPS2,CCL5,CCNE2,CD38,CD74,CDH5,CDK1,CELSR1,CENPF,CHMP4C,COLQ,COMP,CTNS,CYLD,DAB2,DERL3,DOP1A,DTX3L,DYNLT1,EDN1,EGR2,ESCO2,FCN1,FYB1,GBP1,GBP2,GBP5,GHRL,GLUL,GSDMD,HCAR2,HLA-DRB1,IFI27,IFT122,IL12A,IL1RN,ITSN1,JAK2,KPNA5,LAMP3,LAMP5,LIMK2,LMTK2,LRP5,LRRK2,MAP1LC3C,MCOLN2,MMD,MVP,NCF1,NECAB2,NRCAM,NRP1,OPTN,P2RX7,PARP3,PARP9,PID1,PLEK,PML,PTPRU,PYHIN1,RAB20,RAPGEF2,REEP1,RSAD2,RTP4,S100A10,S100A13,SCG3,SCIN,SIDT2,SNX10,SNX20,SPTBN4,SRI,STX11,STX1A,SUCNR1,SYNE1,TAP1,TAP2,TESC,TMEM150A,TMSB10,TNFAIP6,TONSL,TRIM17,TRIM22,TRIM69,TSPAN15,VAMP5,VEGFC,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0016050","Term":"vesicle organization","Annotated":335,"Significant":15,"Expected":20.23,"Rank in p.value_classic":4527,"p.value_elim":0.99311,"p.value_classic":0.91352,"genes":"ATP13A2,CHMP4C,DNM1,DTNBP1,ERC2,F2RL3,P2RX7,PRRT2,RAB20,S100A10,SLAMF1,SNX10,STX11,STX1A,SYT1"} {"GO.ID":"GO:0042303","Term":"molting cycle","Annotated":81,"Significant":1,"Expected":4.89,"Rank in p.value_classic":4877,"p.value_elim":0.99358,"p.value_classic":0.99367,"genes":"EDA"} {"GO.ID":"GO:0043255","Term":"regulation of carbohydrate biosynthetic process","Annotated":81,"Significant":1,"Expected":4.89,"Rank in p.value_classic":4878,"p.value_elim":0.99358,"p.value_classic":0.99367,"genes":"PLEK"} {"GO.ID":"GO:0042633","Term":"hair cycle","Annotated":81,"Significant":1,"Expected":4.89,"Rank in p.value_classic":4879,"p.value_elim":0.99358,"p.value_classic":0.99367,"genes":"EDA"} {"GO.ID":"GO:2000781","Term":"positive regulation of double-strand break repair","Annotated":82,"Significant":1,"Expected":4.95,"Rank in p.value_classic":4880,"p.value_elim":0.99397,"p.value_classic":0.99405,"genes":"PARP3"} {"GO.ID":"GO:0001657","Term":"ureteric bud development","Annotated":82,"Significant":1,"Expected":4.95,"Rank in p.value_classic":4881,"p.value_elim":0.99397,"p.value_classic":0.99405,"genes":"AGT"} {"GO.ID":"GO:0022607","Term":"cellular component assembly","Annotated":2563,"Significant":146,"Expected":154.79,"Rank in p.value_classic":4108,"p.value_elim":0.9942,"p.value_classic":0.80431,"genes":"ABLIM3,AGT,AIM2,ANK2,ANLN,ANTXR1,APPL2,ASB2,ASIC1,ATP8B1,AURKB,B2M,BAZ1A,BCL2L11,BIRC5,BRCA1,CASP4,CD40,CD74,CDC45,CDH5,CDK1,CDKL1,CDS1,CDT1,CENPF,CENPK,CHAF1B,CHMP4C,CIBAR1,COLQ,COMP,CTNS,CYLD,DAB2,DMC1,DNAAF1,DNM1,EDN1,EPHB3,ERC2,EXO1,FAM107A,FAS,FGD5,FSCN1,GABRA3,GBP1,GBP2,GBP5,GCH1,GHRL,GJD3,GSDMD,H2BC21,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,HORMAD1,ICAM1,IFIH1,IFT122,IQGAP3,ITGB5,JAK2,KCNJ10,KCNJ2,KCTD14,KIF11,KIF23,LGI2,LIMK2,LRRC61,LRRK2,MAP1LC3C,MARVELD2,MCM2,MDGA1,MEFV,MSRB1,MTSS1,MYBL2,MYO7B,MYOZ2,NDC80,NRCAM,NRP1,OIP5,ONECUT2,P2RX7,PLEK,PML,POMP,PPM1E,PRC1,PRRT2,PSTPIP2,PTGER4,PXN,RAB20,RALB,RAPGEF2,REPS2,RIPK2,RNF213,RRM2,RUFY4,S100A10,S1PR1,SCIN,SCO2,SNX10,SOAT1,SPTBN4,SSBP3,STAP1,STEAP4,STMN1,STX1A,SYT1,TAL1,TAPBP,TAPBPL,THBS2,TIFA,TK1,TMSB10,TRABD2A,TRIM31,UBD,UHRF1,WARS1,WDR62,ZC3H12A"} {"GO.ID":"GO:0016197","Term":"endosomal transport","Annotated":274,"Significant":8,"Expected":16.55,"Rank in p.value_classic":4887,"p.value_elim":0.99426,"p.value_classic":0.99441,"genes":"ARL4C,CHMP4C,DAB2,ITSN1,LMTK2,LRRK2,REPS2,RHOBTB3"} {"GO.ID":"GO:0030216","Term":"keratinocyte differentiation","Annotated":83,"Significant":1,"Expected":5.01,"Rank in p.value_classic":4883,"p.value_elim":0.99434,"p.value_classic":0.99441,"genes":"PLAAT4"} {"GO.ID":"GO:0072384","Term":"organelle transport along microtubule","Annotated":83,"Significant":1,"Expected":5.01,"Rank in p.value_classic":4884,"p.value_elim":0.99434,"p.value_classic":0.99441,"genes":"DTNBP1"} {"GO.ID":"GO:0072163","Term":"mesonephric epithelium development","Annotated":83,"Significant":1,"Expected":5.01,"Rank in p.value_classic":4885,"p.value_elim":0.99434,"p.value_classic":0.99441,"genes":"AGT"} {"GO.ID":"GO:0072164","Term":"mesonephric tubule development","Annotated":83,"Significant":1,"Expected":5.01,"Rank in p.value_classic":4886,"p.value_elim":0.99434,"p.value_classic":0.99441,"genes":"AGT"} {"GO.ID":"GO:0043413","Term":"macromolecule glycosylation","Annotated":201,"Significant":5,"Expected":12.14,"Rank in p.value_classic":4888,"p.value_elim":0.99438,"p.value_classic":0.99451,"genes":"DERL3,GALNT18,GCNT3,IL15,TMTC1"} {"GO.ID":"GO:0006486","Term":"protein glycosylation","Annotated":201,"Significant":5,"Expected":12.14,"Rank in p.value_classic":4889,"p.value_elim":0.99438,"p.value_classic":0.99451,"genes":"DERL3,GALNT18,GCNT3,IL15,TMTC1"} {"GO.ID":"GO:0090150","Term":"establishment of protein localization to membrane","Annotated":251,"Significant":7,"Expected":15.16,"Rank in p.value_classic":4890,"p.value_elim":0.99446,"p.value_classic":0.9946,"genes":"COLQ,NCF1,OPTN,REEP1,RTP4,VAMP5,ZDHHC19"} {"GO.ID":"GO:0009057","Term":"macromolecule catabolic process","Annotated":1248,"Significant":56,"Expected":75.37,"Rank in p.value_classic":4894,"p.value_elim":0.99458,"p.value_classic":0.99493,"genes":"ADAM8,AMER1,ASB2,ATP13A2,CASP7,CCNF,CEACAM1,CHMP4C,CTRL,CTSL,CTSO,CTSS,DAB2,DAZL,DERL3,DTL,DTX3L,E2F1,FBXO6,FEM1C,FEN1,G6PC1,GTPBP1,IFI27,ISG20,LAMP3,LRRK2,LYVE1,MAD2L1,NUB1,OAS2,P2RX7,PMAIP1,PML,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RHOBTB3,RNF19B,RNF213,SAMD4A,SIDT2,SLC11A1,SOX17,TBX21,TRIM31,TSPAN15,UBD,UBE2L6,UHRF1,WWP1,XRN1,ZC3H12A"} {"GO.ID":"GO:1990542","Term":"mitochondrial transmembrane transport","Annotated":84,"Significant":1,"Expected":5.07,"Rank in p.value_classic":4891,"p.value_elim":0.99468,"p.value_classic":0.99475,"genes":"SLC25A28"} {"GO.ID":"GO:0043933","Term":"protein-containing complex organization","Annotated":2068,"Significant":116,"Expected":124.9,"Rank in p.value_classic":4191,"p.value_elim":0.99468,"p.value_classic":0.82752,"genes":"AGT,AIM2,ANLN,APPL2,ASB2,ASIC1,B2M,BAZ1A,BCL2L11,BCL6,BRCA1,CALCOCO2,CASP4,CD40,CD74,CDC45,CDH5,CDK1,CDT1,CENPF,CENPK,CHAF1B,CHMP4C,COMP,CYLD,DAB2,DMC1,DNAAF1,DNM1,DTX3L,EPOP,ERC2,ERCC6L,FAM107A,FAS,FSCN1,GBP1,GBP2,GBP5,GCH1,GSDMD,H2BC21,HELLS,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,IFIH1,IRF4,JADE2,JAK2,KCNJ2,KCTD14,KIF18B,LPL,LRRC61,LRRK2,MAP1LC3C,MCM2,MEFV,MICAL2,MKI67,MSRB1,NPM2,OIP5,P2RX7,PADI2,PARP10,PLEK,PML,POMP,PRRT2,PSTPIP2,PTGER4,PXN,RAD54B,RAD54L,RALB,REPS2,RIPK2,RRM2,SCIN,SCO2,SOAT1,SPTBN4,SSBP3,STEAP4,STMN1,STX1A,SYT1,TAL1,TAPBP,TAPBPL,TDRD9,TGM2,TIFA,TK1,TMSB10,TONSL,TRABD2A,TRIM31,UHRF1,WARS1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0070585","Term":"protein localization to mitochondrion","Annotated":119,"Significant":2,"Expected":7.19,"Rank in p.value_classic":4893,"p.value_elim":0.99483,"p.value_classic":0.99492,"genes":"ABLIM3,LRRK2"} {"GO.ID":"GO:0001823","Term":"mesonephros development","Annotated":85,"Significant":1,"Expected":5.13,"Rank in p.value_classic":4895,"p.value_elim":0.995,"p.value_classic":0.99507,"genes":"AGT"} {"GO.ID":"GO:0006810","Term":"transport","Annotated":3438,"Significant":216,"Expected":207.64,"Rank in p.value_classic":2076,"p.value_elim":0.99501,"p.value_classic":0.25509,"genes":"ABCB1,ABCC11,ABCG2,ACSL1,ADAM8,ADORA3,AGR2,AGT,ANK2,ANKH,ANO4,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARL4C,ASIC1,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,B2M,BCL2A1,BCL2L11,C1QTNF5,C2,C3,C4A,C4B,CACNA2D3,CADPS2,CALHM6,CAMK2D,CCL5,CCL8,CD163,CD300LF,CD38,CD74,CD93,CDK1,CEACAM1,CENPF,CHMP4C,CLEC10A,CLEC9A,CLIC5,COLEC12,COMP,CRHBP,CTNS,CTSL,CTSS,CXADR,CXCL10,CXCL11,CXCL9,CYSLTR1,DAB2,DERL3,DLL1,DNAAF1,DNM1,DOP1A,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EEPD1,EGR2,ENPP2,ERC2,EXOC3L1,EXOC3L4,F2RL3,FCN1,FLVCR2,G6PC1,GABRA3,GCNT3,GHRL,GJD3,GRAMD1B,GRIN3A,GSDMA,GSDMD,HAVCR1,HCAR2,HLA-DRB1,HLA-F,HRH2,IFI27,IFT122,IGF2R,IL12A,IL15,IL15RA,IL1RN,ITSN1,JAK2,KCNE5,KCNJ10,KCNJ15,KCNJ2,KPNA5,LGALS3BP,LILRA2,LMTK2,LRP5,LRRK2,LY75,LYN,LYVE1,MAP1LC3C,MCOLN2,MCTP2,MERTK,MMP9,MVP,MYO7B,MYOF,NECAB2,NOD2,NPR1,NR4A3,NRP1,OAS2,OCA2,OPTN,OSBPL6,OSM,P2RX4,P2RX7,PDE4B,PID1,PIM1,PKD1L3,PLEK,PLPP4,PLSCR1,PLSCR4,PMAIP1,PML,PRRT2,RAB20,RALB,RBP7,REPS2,RHOBTB3,RSAD2,S100A10,S100A13,SCARF1,SCIN,SCN4B,SEPTIN4,SERINC5,SIDT1,SIDT2,SLAMF1,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SNX10,SNX20,SOAT1,SPTBN4,SRI,STAP1,STEAP4,STX11,STX1A,SUCNR1,SV2B,SYNE1,SYNGR3,SYT1,SYT6,TAP1,TAP2,TAPBP,TESC,TGM2,TICAM2,TIFAB,TMEM109,TMEM144,TNFAIP2,TNFAIP8L3,TNFRSF11A,TPCN1,TRDN,TTC39B,TYRO3,USP6NL,VAMP5,VEGFC,VPS9D1,WWP1,XKR6,ZC3H12A"} {"GO.ID":"GO:0050657","Term":"nucleic acid transport","Annotated":150,"Significant":3,"Expected":9.06,"Rank in p.value_classic":4896,"p.value_elim":0.9951,"p.value_classic":0.9952,"genes":"MVP,SIDT1,SIDT2"} {"GO.ID":"GO:0050658","Term":"RNA transport","Annotated":150,"Significant":3,"Expected":9.06,"Rank in p.value_classic":4897,"p.value_elim":0.9951,"p.value_classic":0.9952,"genes":"MVP,SIDT1,SIDT2"} {"GO.ID":"GO:0030148","Term":"sphingolipid biosynthetic process","Annotated":86,"Significant":1,"Expected":5.19,"Rank in p.value_classic":4898,"p.value_elim":0.99531,"p.value_classic":0.99537,"genes":"P2RX7"} {"GO.ID":"GO:0016441","Term":"post-transcriptional gene silencing","Annotated":86,"Significant":1,"Expected":5.19,"Rank in p.value_classic":4899,"p.value_elim":0.99531,"p.value_classic":0.99537,"genes":"MIR503"} {"GO.ID":"GO:0007507","Term":"heart development","Annotated":503,"Significant":18,"Expected":30.38,"Rank in p.value_classic":4901,"p.value_elim":0.99547,"p.value_classic":0.99564,"genes":"ANK2,ASB2,CASP7,CDK1,CXADR,DHRS3,DLL1,DNAAF1,EDN1,IFT122,MICAL2,NRP1,PIM1,S1PR1,SOX17,SRI,SYNE1,VCAM1"} {"GO.ID":"GO:0017015","Term":"regulation of transforming growth factor beta receptor signaling pathway","Annotated":122,"Significant":2,"Expected":7.37,"Rank in p.value_classic":4902,"p.value_elim":0.99562,"p.value_classic":0.9957,"genes":"HTRA1,ONECUT2"} {"GO.ID":"GO:0019538","Term":"protein metabolic process","Annotated":4039,"Significant":224,"Expected":243.94,"Rank in p.value_classic":4664,"p.value_elim":0.99567,"p.value_classic":0.94855,"genes":"AATK,ADAM8,ADAMTS15,ADGB,AGT,AIM2,ALAS1,AMER1,APOL1,APOL2,APOL3,APOL4,APOL6,ASB2,ATP13A2,AURKB,B2M,BANK1,BIRC5,BRCA1,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CCL5,CCNA2,CCNE2,CCNF,CD28,CD40,CD74,CD80,CDC25A,CDC6,CDCA3,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CFB,CFH,CHAC1,CHMP4C,CISH,CLEC6A,CLSPN,CNDP2,COMP,CSF1,CTRL,CTSL,CTSO,CTSS,CX3CR1,CYLD,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DHFR,DNPEP,DSCC1,DSE,DTL,DTNBP1,DTX3L,ECEL1,EDN1,EGR2,ENPP2,EPAS1,EPHB3,ERAP2,ESCO2,FAM107A,FAM111B,FAM20A,FAS,FAXDC2,FBXO6,FCN1,FEM1C,GAL3ST4,GALNT18,GCNT3,GGT5,GLUL,GRAMD4,GSAP,GTPBP1,HBEGF,HGF,HLA-DRB1,HTRA1,IFI27,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,LACTB,LAMP3,LAP3,LILRA2,LIMK2,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MEFV,MERTK,MIR503,MMD,MMP25,MMP9,MSRB1,MVP,NCF1,NECAB2,NLRP12,NMI,NOD2,NRP1,NUB1,OSM,OTUD1,P2RX7,PARP10,PARP12,PARP14,PARP3,PARP9,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PMAIP1,PML,PPM1E,PRKX,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTPRU,PYHIN1,RALB,RAPGEF2,RHOBTB3,RIPK2,RNF141,RNF19B,RNF213,S100A10,SAMD4A,SEPTIN4,SERPING1,SLC11A1,SOAT1,SOCS1,SOX17,SPTBN4,STAMBPL1,STAT2,STX1A,SUCNR1,TANK,TAPBP,TBX21,TESC,TGM2,THBD,TLR7,TLR8,TMEM119,TMTC1,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,VEGFC,VRK2,WARS1,WEE1,WWP1,XRN1,XYLT1,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0051236","Term":"establishment of RNA localization","Annotated":153,"Significant":3,"Expected":9.24,"Rank in p.value_classic":4903,"p.value_elim":0.9958,"p.value_classic":0.99588,"genes":"MVP,SIDT1,SIDT2"} {"GO.ID":"GO:0046467","Term":"membrane lipid biosynthetic process","Annotated":123,"Significant":2,"Expected":7.43,"Rank in p.value_classic":4904,"p.value_elim":0.99586,"p.value_classic":0.99593,"genes":"GAL3ST4,P2RX7"} {"GO.ID":"GO:1903844","Term":"regulation of cellular response to transforming growth factor beta stimulus","Annotated":124,"Significant":2,"Expected":7.49,"Rank in p.value_classic":4905,"p.value_elim":0.99608,"p.value_classic":0.99615,"genes":"HTRA1,ONECUT2"} {"GO.ID":"GO:1902414","Term":"protein localization to cell junction","Annotated":89,"Significant":1,"Expected":5.38,"Rank in p.value_classic":4906,"p.value_elim":0.99611,"p.value_classic":0.99617,"genes":"CDH5"} {"GO.ID":"GO:0045739","Term":"positive regulation of DNA repair","Annotated":125,"Significant":2,"Expected":7.55,"Rank in p.value_classic":4907,"p.value_elim":0.99629,"p.value_classic":0.99636,"genes":"BRCA1,PARP3"} {"GO.ID":"GO:0051668","Term":"localization within membrane","Annotated":615,"Significant":23,"Expected":37.14,"Rank in p.value_classic":4909,"p.value_elim":0.99631,"p.value_classic":0.99648,"genes":"AGR2,ANK2,ARL4C,COLQ,DAB2,FYB1,GBP1,LMTK2,NCF1,NECAB2,OPTN,PID1,RAPGEF2,REEP1,RTP4,S100A10,SPTBN4,TESC,TMEM150A,TNFAIP6,TSPAN15,VAMP5,ZDHHC19"} {"GO.ID":"GO:0006664","Term":"glycolipid metabolic process","Annotated":90,"Significant":1,"Expected":5.44,"Rank in p.value_classic":4908,"p.value_elim":0.99635,"p.value_classic":0.9964,"genes":"GAL3ST4"} {"GO.ID":"GO:0034248","Term":"regulation of amide metabolic process","Annotated":401,"Significant":13,"Expected":24.22,"Rank in p.value_classic":4910,"p.value_elim":0.99637,"p.value_classic":0.9965,"genes":"BANK1,CCL5,CD28,DAZL,DHFR,GSAP,MIR503,NOD2,PDK4,PIWIL4,SAMD4A,TYMS,XRN1"} {"GO.ID":"GO:0006470","Term":"protein dephosphorylation","Annotated":185,"Significant":4,"Expected":11.17,"Rank in p.value_classic":4911,"p.value_elim":0.99654,"p.value_classic":0.99661,"genes":"CDH5,DAPP1,PPM1E,PTPRU"} {"GO.ID":"GO:1903509","Term":"liposaccharide metabolic process","Annotated":91,"Significant":1,"Expected":5.5,"Rank in p.value_classic":4912,"p.value_elim":0.99657,"p.value_classic":0.99662,"genes":"GAL3ST4"} {"GO.ID":"GO:0051649","Term":"establishment of localization in cell","Annotated":1712,"Significant":83,"Expected":103.4,"Rank in p.value_classic":4847,"p.value_elim":0.99672,"p.value_classic":0.99006,"genes":"ANO4,APPL2,ARL4C,ASIC1,ATP13A2,ATP6V0D2,AURKB,BIRC5,CADPS2,CD74,CDCA5,CDK1,CDT1,CEACAM1,CENPF,CHMP4C,CYSLTR1,DAB2,DERL3,DNM1,DOP1A,DTNBP1,DTX3L,DYNLT1,DYSF,EGR2,EML4,ERC2,GHRL,GRAMD1B,HLA-DRB1,HLA-F,IFI27,IFT122,IGF2R,ITSN1,JAK2,KCNJ10,KPNA5,LIMK2,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MAP1LC3C,MCTP2,MERTK,MYOF,NDC80,NOD2,NR4A3,NUF2,NUSAP1,P2RX7,PLEK,PML,PRRT2,RAB20,REPS2,RHOBTB3,S100A13,SCN4B,SIDT2,SLC11A1,SLC18A1,SLC6A12,SNX10,SPC24,SPC25,SRI,STEAP4,STX11,STX1A,SV2B,SYNE1,SYT1,TAP1,TAP2,TRDN,TYRO3,ZC3H12A,ZWINT"} {"GO.ID":"GO:0006913","Term":"nucleocytoplasmic transport","Annotated":312,"Significant":9,"Expected":18.84,"Rank in p.value_classic":4913,"p.value_elim":0.99672,"p.value_classic":0.99682,"genes":"APPL2,CDK1,EGR2,IFI27,JAK2,KPNA5,LRRK2,PML,ZC3H12A"} {"GO.ID":"GO:0051169","Term":"nuclear transport","Annotated":312,"Significant":9,"Expected":18.84,"Rank in p.value_classic":4914,"p.value_elim":0.99672,"p.value_classic":0.99682,"genes":"APPL2,CDK1,EGR2,IFI27,JAK2,KPNA5,LRRK2,PML,ZC3H12A"} {"GO.ID":"GO:0009987","Term":"cellular process","Annotated":12425,"Significant":750,"Expected":750.41,"Rank in p.value_classic":3170,"p.value_elim":0.99687,"p.value_classic":0.5688,"genes":"AATK,ABCB1,ABCC11,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADGRE5,ADGRG5,ADORA3,AGR2,AGT,AIFM2,AIM2,AK1,AKAP7,ALAS1,AMER1,AMOT,ANK2,ANKH,ANLN,ANO4,ANTXR1,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL3,APPL2,ARAP2,ARL4C,ARMT1,ASB2,ASCL2,ASIC1,ATF3,ATF5,ATP13A2,ATP1B2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL2A1,BCL2L11,BCL2L14,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C1QB,C1QTNF5,C1R,C1RL,C2,C21orf91,C3,C3orf38,C4A,C4B,CA11,CACNA2D3,CADPS2,CALCOCO2,CALHM6,CAMK2D,CARD16,CASP4,CASP7,CASTOR1,CASZ1,CBLN3,CBR3,CCDC170,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CCNA2,CCNE2,CCNF,CCRL2,CD101,CD163,CD1A,CD1C,CD274,CD28,CD300H,CD300LF,CD38,CD40,CD69,CD7,CD74,CD80,CD83,CD93,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CENPK,CENPM,CENPU,CFH,CHAC1,CHAF1B,CHMP4C,CHRD,CHTF18,CIBAR1,CIITA,CISH,CLEC10A,CLEC6A,CLEC9A,CLIC5,CLSPN,CMPK2,COL23A1,COL9A2,COLEC12,COLGALT2,COLQ,COMP,CR1L,CRHBP,CSF1,CSF2RB,CTLA4,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,CXCR3,CYLD,CYP1A1,CYSLTR1,CYSLTR2,DAB1,DAB2,DAPP1,DAZL,DDX60,DEPDC7,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DIAPH2-AS1,DKK2,DLGAP3,DLL1,DMC1,DNAAF1,DNM1,DOP1A,DPYS,DRAM1,DSCC1,DSE,DTL,DTNBP1,DTX3L,DYNLT1,DYNLT5,DYSF,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,EML4,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ERC2,ERCC6L,ESCO2,ETV7,EXO1,EXOC3L1,EXOC3L4,F2RL3,FAM107A,FAM111B,FAM13A,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEN1,FGD5,FGL1,FGL2,FLT3LG,FLVCR2,FMNL2,FRMD3,FSCN1,FSTL4,FYB1,G0S2,G6PC1,GABRA3,GADD45B,GAL3ST4,GALNT18,GAREM1,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GCNT3,GFRA2,GGT5,GHRL,GIMAP7,GIMAP8,GINS1,GINS2,GJD3,GK,GLDN,GLIPR2,GLUL,GNG2,GOLM1,GPR183,GPR31,GRAMD1B,GRAMD4,GRIN3A,GRM8,GSDMA,GSDMD,GSTK1,GTPBP1,GTSE1,H2BC21,HAPLN3,HAVCR1,HBEGF,HCAR2,HCAR3,HELLS,HESX1,HGF,HIVEP2,HJURP,HLA-A,HLA-B,HLA-C,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,HLA-G,HORMAD1,HRH2,HSBP1L1,HSD3B7,HSH2D,HTRA1,HYI,ICAM1,ICAM2,IDO1,IDO2,IFI27,IFI35,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IFT122,IGF2R,IGSF6,IL12A,IL12RB1,IL12RB2,IL15,IL15RA,IL18BP,IL1RN,IL22RA2,IL27,IL31RA,IL32,IL3RA,IL4I1,IL7,INA,INSYN2A,IQGAP3,IRAG1,IRF1,IRF4,IRF7,ISG20,ITGA7,ITGB1BP2,ITGB5,ITK,ITSN1,JADE2,JAK2,JAK3,KARS1,KCNE5,KCNJ10,KCNJ15,KCNJ2,KCTD14,KIF11,KIF15,KIF18B,KIF23,KIF26A,KITLG,KLF4,KLRK1,KPNA5,KREMEN1,LAG3,LAMB3,LAMP3,LAMP5,LBH,LCLAT1,LGALS3BP,LGI2,LILRA1,LILRA2,LILRB3,LIMK2,LITAF,LMTK2,LPL,LRATD1,LRP5,LRRC61,LRRK2,LTA,LTC4S,LY75,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MAP1LC3C,MARCKSL1,MARVELD2,MCF2L,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MCTP2,MDGA1,MEFV,MEIKIN,MERTK,MICAL2,MIR503,MKI67,MMD,MMP25,MMP9,MPZL2,MRAS,MSRB1,MT2A,MTHFD2,MTSS1,MTUS1,MUC1,MVP,MYBL2,MYO7B,MYOF,MYOZ2,NAAA,NCAPG,NCAPG2,NCAPH,NCF1,NCF1C,NDC80,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRCAM,NRGN,NRK,NRN1,NRP1,NUCB1,NUF2,NUSAP1,NXPH2,NYAP2,OAS2,OAS3,OCA2,OIP5,OLFML2B,OLIG1,ONECUT2,OPTN,OR2I1P,ORC1,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,P2RY14,PADI2,PAQR5,PAQR8,PARP10,PARP14,PARP3,PARP9,PCDH12,PCDHGC3,PCLAF,PCYT1A,PDCD1,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKD1L3,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POLB,POLE2,POMP,PPA1,PPM1E,PRC1,PRKX,PROK2,PRRT2,PRTFDC1,PSMB10,PSMB8,PSME1,PSME2,PSTPIP2,PTGER4,PTPRU,PXN,PYHIN1,PYROXD2,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGEF1C,RASGRF1,RECQL4,REEP1,RELB,REPS2,RGS18,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,RSAD2,RSU1,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCARF1,SCG3,SCIMP,SCIN,SCN4B,SCO2,SDC2,SDC3,SECTM1,SELENOP,SELL,SEMA6B,SEPTIN4,SERINC5,SESN3,SGPL1,SH3PXD2A,SHCBP1,SIDT2,SIGLEC12,SIT1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,SLC12A3,SLC16A10,SLC18A1,SLC20A1,SLC25A28,SLC25A45,SLC2A5,SLC2A6,SLC31A2,SLC37A1,SLC45A3,SLC45A4,SLC4A7,SLC6A12,SNX10,SNX20,SOAT1,SOCS1,SOX17,SP110,SP140,SPATA9,SPC24,SPC25,SPTBN4,SQOR,SRI,SSBP3,SSPN,SSTR2,STAMBPL1,STAP1,STAT1,STAT2,STEAP4,STMN1,STX11,STX1A,SUCNR1,SV2B,SYNC,SYNE1,SYNGR3,SYT1,SYT6,TACC2,TAGAP,TAL1,TANK,TAP1,TAP2,TAPBP,TAPBPL,TBATA,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,THBS2,TICAM2,TICRR,TIFA,TIFAB,TK1,TLR10,TLR5,TLR7,TLR8,TMEM109,TMEM119,TMEM144,TMEM150A,TMEM176A,TMEM176B,TMSB10,TMTC1,TNFAIP2,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF13B,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TPCN1,TRABD2A,TRDN,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TSPAN32,TYMP,TYMS,TYRO3,UBD,UBE2T,UHRF1,UNG,USP53,USP6NL,VAMP5,VCAM1,VCAN,VEGFC,VPS9D1,VRK2,WARS1,WDR62,WDR76,WEE1,WWP1,XAF1,XIRP1,XKR6,XRCC2,XRN1,XYLT1,ZBP1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1,ZWINT"} {"GO.ID":"GO:0070085","Term":"glycosylation","Annotated":214,"Significant":5,"Expected":12.92,"Rank in p.value_classic":4915,"p.value_elim":0.99687,"p.value_classic":0.99695,"genes":"DERL3,GALNT18,GCNT3,IL15,TMTC1"} {"GO.ID":"GO:0007409","Term":"axonogenesis","Annotated":360,"Significant":11,"Expected":21.74,"Rank in p.value_classic":4916,"p.value_elim":0.99689,"p.value_classic":0.99699,"genes":"DAB1,EDN1,EGR2,EPHB3,FSTL4,NRCAM,NRP1,PLXNA2,SEMA6B,SPTBN4,STMN1"} {"GO.ID":"GO:0042773","Term":"ATP synthesis coupled electron transport","Annotated":93,"Significant":1,"Expected":5.62,"Rank in p.value_classic":4917,"p.value_elim":0.99697,"p.value_classic":0.99702,"genes":"CDK1"} {"GO.ID":"GO:0042775","Term":"mitochondrial ATP synthesis coupled electron transport","Annotated":93,"Significant":1,"Expected":5.62,"Rank in p.value_classic":4918,"p.value_elim":0.99697,"p.value_classic":0.99702,"genes":"CDK1"} {"GO.ID":"GO:0006367","Term":"transcription initiation at RNA polymerase II promoter","Annotated":129,"Significant":2,"Expected":7.79,"Rank in p.value_classic":4919,"p.value_elim":0.99703,"p.value_classic":0.99709,"genes":"E2F2,PADI2"} {"GO.ID":"GO:0007224","Term":"smoothened signaling pathway","Annotated":129,"Significant":2,"Expected":7.79,"Rank in p.value_classic":4920,"p.value_elim":0.99703,"p.value_classic":0.99709,"genes":"CIBAR1,IFT122"} {"GO.ID":"GO:0048706","Term":"embryonic skeletal system development","Annotated":95,"Significant":1,"Expected":5.74,"Rank in p.value_classic":4921,"p.value_elim":0.99733,"p.value_classic":0.99737,"genes":"XYLT1"} {"GO.ID":"GO:1901135","Term":"carbohydrate derivative metabolic process","Annotated":935,"Significant":45,"Expected":56.47,"Rank in p.value_classic":4704,"p.value_elim":0.99733,"p.value_classic":0.95941,"genes":"ACOT4,ACSL1,AK1,APOBEC3A,APOBEC3D,APOBEC3G,CMPK2,CTNS,CTSL,DERL3,DGAT2,DPYS,DSE,ENPP4,FBXO6,G6PC1,GAL3ST4,GALNT18,GCNT3,GIMAP7,GK,GTPBP1,HBEGF,IL15,JAK3,LRRK2,LYVE1,NECAB2,NPR1,P2RX7,PDE4B,PDK4,PID1,PRTFDC1,RRM2,SLC2A6,SOAT1,TK1,TMTC1,TNFAIP6,TYMP,TYMS,UNG,VPS9D1,XYLT1"} {"GO.ID":"GO:0006417","Term":"regulation of translation","Annotated":341,"Significant":10,"Expected":20.59,"Rank in p.value_classic":4923,"p.value_elim":0.99734,"p.value_classic":0.99743,"genes":"BANK1,CCL5,CD28,DAZL,DHFR,MIR503,PIWIL4,SAMD4A,TYMS,XRN1"} {"GO.ID":"GO:0016051","Term":"carbohydrate biosynthetic process","Annotated":162,"Significant":3,"Expected":9.78,"Rank in p.value_classic":4922,"p.value_elim":0.99735,"p.value_classic":0.99741,"genes":"ATF3,G6PC1,PLEK"} {"GO.ID":"GO:0048667","Term":"cell morphogenesis involved in neuron differentiation","Annotated":478,"Significant":16,"Expected":28.87,"Rank in p.value_classic":4924,"p.value_elim":0.99747,"p.value_classic":0.99757,"genes":"DAB1,DTNBP1,EDN1,EGR2,EPHB3,FSTL4,LRRK2,NRCAM,NRP1,PLXNA2,RAPGEF2,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1"} {"GO.ID":"GO:0010629","Term":"negative regulation of gene expression","Annotated":935,"Significant":65,"Expected":56.47,"Rank in p.value_classic":1528,"p.value_elim":0.99752,"p.value_classic":0.12728,"genes":"ACOD1,APPL2,BANK1,BAZ1A,BCL6,BRCA1,BTN2A2,CARD16,CD274,CD28,CD83,CDK1,CEACAM1,CHAC1,CX3CR1,CYLD,DAZL,DHFR,DLL1,E2F1,EDN1,GBP1,GBP7,GHRL,GTPBP1,HELLS,HGF,HLA-DRB1,HLA-F,IDO1,IL12A,IQGAP3,JAK3,KLF4,LAG3,LRRK2,MEFV,MERTK,MIR503,NLRP12,NMI,NOD2,OAS3,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PIWIL4,PML,PTGER4,RELB,SAMD4A,SLAMF1,SLC11A1,TBX21,TDRD9,TLR8,TNFRSF21,TYMS,UHRF1,XAF1,XRN1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0032989","Term":"cellular anatomical entity morphogenesis","Annotated":629,"Significant":23,"Expected":37.99,"Rank in p.value_classic":4925,"p.value_elim":0.99755,"p.value_classic":0.99767,"genes":"ANK2,DAB1,DTNBP1,EDN1,EGR2,ENPP2,EPHB3,FSTL4,LRRK2,MYOZ2,NRCAM,NRN1,NRP1,NYAP2,PLXNA2,RAPGEF2,SDC2,SEMA6B,SPTBN4,STMN1,SYNE1,SYT1,WEE1"} {"GO.ID":"GO:0045184","Term":"establishment of protein localization","Annotated":1498,"Significant":67,"Expected":90.47,"Rank in p.value_classic":4927,"p.value_elim":0.99772,"p.value_classic":0.9979,"genes":"ABLIM3,ADAM8,ANK2,APPL2,ARL4C,ATP13A2,C1QTNF5,CADPS2,CCL5,CD38,CD74,CDK1,CENPF,CHMP4C,COLQ,COMP,CTNS,DAB2,DERL3,DOP1A,DTX3L,DYNLT1,EGR2,GBP5,GHRL,GSDMD,HCAR2,HLA-DRB1,IFI27,IFT122,IL12A,IL1RN,ITSN1,JAK2,KPNA5,LAMP3,LAMP5,LMTK2,LRP5,LRRK2,MAP1LC3C,MCOLN2,MVP,NCF1,OPTN,P2RX7,PLEK,PML,RAB20,REEP1,RSAD2,RTP4,S100A13,SIDT2,SNX10,SNX20,SRI,STX11,STX1A,SUCNR1,TAP1,TAP2,TESC,VAMP5,VEGFC,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0006839","Term":"mitochondrial transport","Annotated":165,"Significant":3,"Expected":9.97,"Rank in p.value_classic":4926,"p.value_elim":0.99773,"p.value_classic":0.99778,"genes":"BCL2L11,PMAIP1,SLC25A28"} {"GO.ID":"GO:0000122","Term":"negative regulation of transcription by RNA polymerase II","Annotated":760,"Significant":29,"Expected":45.9,"Rank in p.value_classic":4928,"p.value_elim":0.99797,"p.value_classic":0.99808,"genes":"ASCL2,ATF3,AURKB,BACH1,BATF3,BCL6,BHLHE41,CIITA,DAB2,E2F1,E2F8,EDN1,ETV7,HESX1,IFI27,IRF7,KLF4,MAF,MAFF,MYOZ2,NR4A3,OVOL1,PARP9,STAT1,TAL1,TBX21,TFEC,UHRF1,ZNF608"} {"GO.ID":"GO:0016043","Term":"cellular component organization","Annotated":5398,"Significant":329,"Expected":326.01,"Rank in p.value_classic":2553,"p.value_elim":0.99803,"p.value_classic":0.42582,"genes":"ABCB1,ABLIM3,ADAM8,ADAMTS15,AGT,AIFM2,AIM2,AMOT,ANK2,ANLN,ANO4,ANTXR1,APPL2,ASB2,ASIC1,ATF5,ATP13A2,ATP1B2,ATP8B1,AURKB,B2M,BAZ1A,BCL2A1,BCL2L11,BCL6,BIRC5,BRCA1,BUB1B,C1QB,C2,C21orf91,C3,C4A,C4B,CALCOCO2,CAMK2D,CASP4,CASP7,CBLN3,CCDC170,CCL13,CCL7,CCNE2,CCNF,CD28,CD300LF,CD38,CD40,CD74,CDC45,CDC6,CDCA5,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CENPK,CHAF1B,CHMP4C,CHTF18,CIBAR1,CISH,COL23A1,COL9A2,COLEC12,COLGALT2,COLQ,COMP,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL9,CYLD,DAB1,DAB2,DAZL,DEPTOR,DHFR,DLGAP3,DLL1,DMC1,DNAAF1,DNM1,DSCC1,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EGR2,EME1,EML4,ENPP2,EPAS1,EPHB3,EPOP,ERC2,ERCC6L,ESCO2,EXO1,F2RL3,FAM107A,FAS,FCN1,FEN1,FGD5,FMNL2,FRMD3,FSCN1,FSTL4,GABRA3,GBP1,GBP2,GBP5,GCH1,GHRL,GINS1,GINS2,GJD3,GLDN,GOLM1,GRAMD1B,GRIN3A,GSDMD,H2BC21,HAVCR1,HBEGF,HELLS,HGF,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,HORMAD1,ICAM1,IFIH1,IFIT2,IFT122,IL15,IL15RA,INA,IQGAP3,IRF4,ITGB5,JADE2,JAK2,KCNJ10,KCNJ2,KCTD14,KIF11,KIF18B,KIF23,KIF26A,KLF4,KREMEN1,LGI2,LIMK2,LPL,LRP5,LRRC61,LRRK2,LYN,MAD2L1,MAP1LC3C,MARCKSL1,MARVELD2,MCM2,MCM4,MCM5,MCM6,MCM7,MDGA1,MEFV,MEIKIN,MERTK,MICAL2,MKI67,MMP25,MMP9,MRAS,MSRB1,MTSS1,MYBL2,MYO7B,MYOF,MYOZ2,NCAPG,NCAPG2,NCAPH,NDC80,NECAB2,NOD2,NPM2,NPR1,NRCAM,NRN1,NRP1,NUF2,NUSAP1,NYAP2,OCA2,OIP5,OLFML2B,OLIG1,ONECUT2,OPTN,P2RX7,PADI2,PARP10,PARP3,PCDHGC3,PCLAF,PID1,PKIB,PKMYT1,PLAAT3,PLEK,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POMP,PPM1E,PRC1,PRRT2,PSTPIP2,PTGER4,PXN,PYROXD2,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGRF1,RECQL4,REEP1,REPS2,RIPK2,RMI2,RNF213,RRM2,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S1PR1,SCARF1,SCIN,SCO2,SDC2,SEMA6B,SLAMF1,SLAMF8,SLC11A1,SLC12A3,SLC4A7,SNX10,SOAT1,SOX17,SPC24,SPC25,SPTBN4,SSBP3,STAP1,STAT2,STEAP4,STMN1,STX11,STX1A,SYNE1,SYT1,TACC2,TAL1,TAPBP,TAPBPL,TDRD9,TGM2,THBS2,TIFA,TK1,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF21,TNFSF10,TONSL,TOP2A,TRABD2A,TRDN,TRIM31,TSPAN32,TYMP,UBD,UHRF1,USP6NL,WARS1,WDR62,WEE1,XIRP1,XKR6,XRCC2,XRN1,ZC3H12A,ZNFX1,ZWINT"} {"GO.ID":"GO:0098781","Term":"ncRNA transcription","Annotated":137,"Significant":2,"Expected":8.27,"Rank in p.value_classic":4929,"p.value_elim":0.9981,"p.value_classic":0.99814,"genes":"AGT,KLF4"} {"GO.ID":"GO:0070925","Term":"organelle assembly","Annotated":858,"Significant":37,"Expected":51.82,"Rank in p.value_classic":4852,"p.value_elim":0.99812,"p.value_classic":0.99094,"genes":"ABLIM3,ANLN,ASB2,AURKB,BIRC5,BRCA1,CDKL1,CDS1,CENPF,CENPK,CHMP4C,CIBAR1,CYLD,DNAAF1,EDN1,FSCN1,IFT122,KCNJ10,KIF11,KIF23,LIMK2,LRRC61,LRRK2,MAP1LC3C,MYBL2,MYOZ2,NDC80,ONECUT2,P2RX7,PRC1,RAB20,RALB,RNF213,RUFY4,SNX10,UHRF1,WDR62"} {"GO.ID":"GO:0033108","Term":"mitochondrial respiratory chain complex assembly","Annotated":101,"Significant":1,"Expected":6.1,"Rank in p.value_classic":4930,"p.value_elim":0.99816,"p.value_classic":0.99819,"genes":"SCO2"} {"GO.ID":"GO:0043412","Term":"macromolecule modification","Annotated":2742,"Significant":151,"Expected":165.6,"Rank in p.value_classic":4530,"p.value_elim":0.9985,"p.value_classic":0.91447,"genes":"AATK,ADARB2,AGT,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,ASB2,ATP13A2,AURKB,BANK1,BIRC5,BRCA1,C3,CAMK2D,CCL5,CCNA2,CCNE2,CCNF,CD40,CD74,CD80,CDC25A,CDC6,CDCA3,CDH5,CDK1,CDKL1,CDKN2C,CEACAM1,CISH,CLEC6A,CLSPN,CSF1,CX3CR1,CYLD,DAB2,DAPP1,DEPTOR,DERL3,DSCC1,DTL,DTNBP1,DTX3L,EDN1,EGR2,ENPP2,EPAS1,EPHB3,ESCO2,FAM107A,FAM20A,FAS,FAXDC2,FBXO6,FEM1C,GALNT18,GCNT3,GLUL,HBEGF,HELLS,HGF,HLA-DRB1,IFI27,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL7,IQGAP3,ITK,JADE2,JAK2,JAK3,KITLG,LIMK2,LMTK2,LRP5,LRRK2,LYN,MAD2L1,MEFV,MERTK,MMD,MMP9,MVP,NCF1,NEIL3,NLRP12,NMI,NOD2,NRP1,NUB1,OSM,OTUD1,P2RX7,PARP10,PARP12,PARP14,PARP3,PARP9,PDK4,PID1,PIM1,PKIB,PKMYT1,PML,PPM1E,PRKX,PTPRU,RALB,RAPGEF2,RIPK2,RNF141,RNF19B,RNF213,SEPTIN4,SLC11A1,SOCS1,SPTBN4,STAMBPL1,STAT2,STX1A,TANK,TGM2,TLR7,TLR8,TMEM119,TMTC1,TNFRSF11A,TNFRSF14,TNFSF18,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VEGFC,VRK2,WARS1,WEE1,WWP1,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0018193","Term":"peptidyl-amino acid modification","Annotated":722,"Significant":45,"Expected":43.61,"Rank in p.value_classic":2589,"p.value_elim":0.99853,"p.value_classic":0.43477,"genes":"AATK,AGT,ATP13A2,BANK1,CAMK2D,CCL5,CD40,CD74,CD80,CDK1,CLEC6A,CLSPN,EGR2,ENPP2,HBEGF,HGF,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL7,JAK2,JAK3,KITLG,LMTK2,LRRK2,LYN,MVP,NCF1,NOD2,NRP1,OSM,PARP14,PARP9,PML,PRKX,RIPK2,SOCS1,SPTBN4,STX1A,TNFRSF14,TNFSF18,VRK2,ZDHHC19"} {"GO.ID":"GO:1901564","Term":"organonitrogen compound metabolic process","Annotated":4880,"Significant":272,"Expected":294.73,"Rank in p.value_classic":4711,"p.value_elim":0.99854,"p.value_classic":0.96154,"genes":"AATK,ABCG2,ACOT4,ACSL1,ADAM8,ADAMTS15,ADGB,AGT,AIM2,AK1,ALAS1,AMER1,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,ASB2,ATP13A2,AURKB,B2M,BANK1,BIRC5,BRCA1,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CCL5,CCNA2,CCNE2,CCNF,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA3,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CEACAM1,CFB,CFH,CHAC1,CHMP4C,CISH,CLEC6A,CLSPN,CMPK2,CNDP2,COMP,CSF1,CTNS,CTRL,CTSL,CTSO,CTSS,CX3CR1,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DNPEP,DPYS,DSCC1,DSE,DTL,DTNBP1,DTX3L,ECEL1,EDN1,EGR2,ENPP2,ENPP4,EPAS1,EPHB3,ERAP2,ESCO2,FAM107A,FAM111B,FAM20A,FAS,FAXDC2,FBXO6,FCN1,FEM1C,G6PC1,GAL3ST4,GALNT18,GCH1,GCNT3,GGT5,GIMAP7,GLUL,GRAMD4,GSAP,GSTK1,GTPBP1,HBEGF,HGF,HLA-DRB1,HTRA1,IDO1,IDO2,IFI27,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,LACTB,LAMP3,LAP3,LILRA2,LIMK2,LMTK2,LRP5,LRRK2,LYN,LYVE1,MAD2L1,MEFV,MERTK,MIR503,MMD,MMP25,MMP9,MSRB1,MTHFD2,MVP,NAAA,NCF1,NECAB2,NLRP12,NMI,NOD2,NPR1,NRP1,NUB1,OCA2,OSM,OTUD1,P2RX7,PARP10,PARP12,PARP14,PARP3,PARP9,PCYT1A,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLSCR1,PMAIP1,PML,PPM1E,PRKX,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTPRU,PYHIN1,RALB,RAPGEF2,RHOBTB3,RIPK2,RNF141,RNF19B,RNF213,S100A10,SAMD4A,SAT1,SEPTIN4,SERINC5,SERPING1,SGPL1,SLC11A1,SLC16A10,SLC2A6,SLC4A7,SOAT1,SOCS1,SOX17,SPTBN4,STAMBPL1,STAT2,STX1A,SUCNR1,TANK,TAPBP,TBX21,TESC,TGM2,THBD,TK1,TLR7,TLR8,TMEM119,TMTC1,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XRN1,XYLT1,ZC3H12A,ZDHHC19"} {"GO.ID":"GO:0016236","Term":"macroautophagy","Annotated":325,"Significant":13,"Expected":19.63,"Rank in p.value_classic":4706,"p.value_elim":0.99868,"p.value_classic":0.96044,"genes":"ATP13A2,ATP6V0D2,CALCOCO2,CHMP4C,LRRK2,MAP1LC3C,NOD2,OPTN,RALB,RIPK2,RNF213,RUFY4,SESN3"} {"GO.ID":"GO:0031327","Term":"negative regulation of cellular biosynthetic process","Annotated":1839,"Significant":108,"Expected":111.07,"Rank in p.value_classic":3472,"p.value_elim":0.99876,"p.value_classic":0.6432,"genes":"ACOD1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDK1,CEACAM1,CENPF,CHAC1,CIITA,CTNS,CX3CR1,CYLD,DAB2,DAZL,DHFR,DLL1,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GHRL,GTPBP1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LBH,LRRK2,MAF,MAFF,MEFV,MERTK,MIR503,MUC1,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PID1,PIWIL4,PLEK,PML,PTGER4,RAPGEF2,RELB,SAMD4A,SBNO2,SLAMF1,SLC11A1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0061919","Term":"process utilizing autophagic mechanism","Annotated":539,"Significant":22,"Expected":32.55,"Rank in p.value_classic":4806,"p.value_elim":0.99884,"p.value_classic":0.98366,"genes":"ATP13A2,ATP6V0D2,CALCOCO2,CHMP4C,DEPTOR,DRAM1,HGF,LAMP3,LRRK2,MAP1LC3C,MEFV,NOD2,OPTN,RALB,RIPK2,RNF213,RUFY4,SESN3,TPCN1,TRIM17,TRIM22,ZC3H12A"} {"GO.ID":"GO:0006914","Term":"autophagy","Annotated":539,"Significant":22,"Expected":32.55,"Rank in p.value_classic":4807,"p.value_elim":0.99884,"p.value_classic":0.98366,"genes":"ATP13A2,ATP6V0D2,CALCOCO2,CHMP4C,DEPTOR,DRAM1,HGF,LAMP3,LRRK2,MAP1LC3C,MEFV,NOD2,OPTN,RALB,RIPK2,RNF213,RUFY4,SESN3,TPCN1,TRIM17,TRIM22,ZC3H12A"} {"GO.ID":"GO:0006091","Term":"generation of precursor metabolites and energy","Annotated":435,"Significant":13,"Expected":26.27,"Rank in p.value_classic":4931,"p.value_elim":0.99893,"p.value_classic":0.99897,"genes":"AIFM2,CDK1,DHRS3,G6PC1,IDO1,NCF1,NR4A3,P2RX7,PCDH12,PID1,SCO2,SLC2A6,STEAP4"} {"GO.ID":"GO:0006282","Term":"regulation of DNA repair","Annotated":210,"Significant":4,"Expected":12.68,"Rank in p.value_classic":4932,"p.value_elim":0.99898,"p.value_classic":0.99901,"genes":"BRCA1,PARP3,PML,RMI2"} {"GO.ID":"GO:0009890","Term":"negative regulation of biosynthetic process","Annotated":1851,"Significant":108,"Expected":111.79,"Rank in p.value_classic":3575,"p.value_elim":0.99904,"p.value_classic":0.67113,"genes":"ACOD1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDK1,CEACAM1,CENPF,CHAC1,CIITA,CTNS,CX3CR1,CYLD,DAB2,DAZL,DHFR,DLL1,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GHRL,GTPBP1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LBH,LRRK2,MAF,MAFF,MEFV,MERTK,MIR503,MUC1,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PID1,PIWIL4,PLEK,PML,PTGER4,RAPGEF2,RELB,SAMD4A,SBNO2,SLAMF1,SLC11A1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0044248","Term":"cellular catabolic process","Annotated":1368,"Significant":62,"Expected":82.62,"Rank in p.value_classic":4900,"p.value_elim":0.99908,"p.value_classic":0.99559,"genes":"ACOT4,ACSL1,ADAM8,APOBEC3A,APOBEC3D,APOBEC3G,ATP13A2,ATP6V0D2,CALCOCO2,CBR3,CHAC1,CHMP4C,CYP1A1,DAZL,DEPTOR,DPYS,DRAM1,DTX3L,E2F1,ENPP2,ENPP4,EPHX1,ERAP2,FEN1,GGT5,GLUL,GTPBP1,HGF,IDO1,IDO2,IL4I1,ISG20,LAMP3,LPL,LRRK2,MAP1LC3C,MEFV,NOD2,OAS2,OPTN,P2RX7,PDE4B,PLB1,PNPLA3,RALB,RIPK2,RNF213,RUFY4,SAMD4A,SESN3,SGPL1,SIDT2,SLC11A1,SLC2A6,TPCN1,TRIM17,TRIM22,TSPAN15,TYMP,UNG,XRN1,ZC3H12A"} {"GO.ID":"GO:0015980","Term":"energy derivation by oxidation of organic compounds","Annotated":294,"Significant":7,"Expected":17.76,"Rank in p.value_classic":4933,"p.value_elim":0.9991,"p.value_classic":0.99913,"genes":"AIFM2,CDK1,G6PC1,NR4A3,PCDH12,PID1,SCO2"} {"GO.ID":"GO:0033365","Term":"protein localization to organelle","Annotated":872,"Significant":33,"Expected":52.66,"Rank in p.value_classic":4935,"p.value_elim":0.99912,"p.value_classic":0.99917,"genes":"ABLIM3,ANK2,APPL2,ATP13A2,AURKB,BUB1B,CDK1,DTX3L,EDN1,ESCO2,GBP1,GBP2,GBP5,GLUL,IFT122,JAK2,KPNA5,LAMP3,LAMP5,LIMK2,LRRK2,NRP1,OPTN,PARP3,PARP9,PML,PYHIN1,SCG3,SNX10,SYNE1,TONSL,TRIM69,ZC3H12A"} {"GO.ID":"GO:0006368","Term":"transcription elongation by RNA polymerase II","Annotated":113,"Significant":1,"Expected":6.82,"Rank in p.value_classic":4934,"p.value_elim":0.99913,"p.value_classic":0.99915,"genes":"EPOP"} {"GO.ID":"GO:0016311","Term":"dephosphorylation","Annotated":269,"Significant":6,"Expected":16.25,"Rank in p.value_classic":4936,"p.value_elim":0.99915,"p.value_classic":0.99918,"genes":"CDH5,DAPP1,PLEK,PLPP4,PPM1E,PTPRU"} {"GO.ID":"GO:1903311","Term":"regulation of mRNA metabolic process","Annotated":270,"Significant":6,"Expected":16.31,"Rank in p.value_classic":4937,"p.value_elim":0.99919,"p.value_classic":0.99921,"genes":"DAZL,E2F1,GTPBP1,SAMD4A,SLC11A1,ZC3H12A"} {"GO.ID":"GO:0006457","Term":"protein folding","Annotated":187,"Significant":3,"Expected":11.29,"Rank in p.value_classic":4938,"p.value_elim":0.99928,"p.value_classic":0.9993,"genes":"B2M,CD74,TAPBP"} {"GO.ID":"GO:0099111","Term":"microtubule-based transport","Annotated":188,"Significant":3,"Expected":11.35,"Rank in p.value_classic":4939,"p.value_elim":0.99932,"p.value_classic":0.99934,"genes":"DNAAF1,DTNBP1,IFT122"} {"GO.ID":"GO:0006403","Term":"RNA localization","Annotated":188,"Significant":3,"Expected":11.35,"Rank in p.value_classic":4940,"p.value_elim":0.99932,"p.value_classic":0.99934,"genes":"MVP,SIDT1,SIDT2"} {"GO.ID":"GO:0006888","Term":"endoplasmic reticulum to Golgi vesicle-mediated transport","Annotated":120,"Significant":1,"Expected":7.25,"Rank in p.value_classic":4941,"p.value_elim":0.99944,"p.value_classic":0.99945,"genes":"LRRK2"} {"GO.ID":"GO:0010558","Term":"negative regulation of macromolecule biosynthetic process","Annotated":1800,"Significant":104,"Expected":108.71,"Rank in p.value_classic":3732,"p.value_elim":0.99948,"p.value_classic":0.70793,"genes":"ACOD1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDK1,CEACAM1,CENPF,CHAC1,CIITA,CX3CR1,CYLD,DAB2,DAZL,DHFR,DLL1,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GHRL,GTPBP1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LBH,LRRK2,MAF,MAFF,MEFV,MERTK,MIR503,MUC1,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PIWIL4,PML,PTGER4,RELB,SAMD4A,SBNO2,SLAMF1,SLC11A1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0010970","Term":"transport along microtubule","Annotated":160,"Significant":2,"Expected":9.66,"Rank in p.value_classic":4942,"p.value_elim":0.99949,"p.value_classic":0.9995,"genes":"DTNBP1,IFT122"} {"GO.ID":"GO:0045333","Term":"cellular respiration","Annotated":224,"Significant":4,"Expected":13.53,"Rank in p.value_classic":4943,"p.value_elim":0.99949,"p.value_classic":0.99951,"genes":"AIFM2,CDK1,NR4A3,SCO2"} {"GO.ID":"GO:0009892","Term":"negative regulation of metabolic process","Annotated":2408,"Significant":135,"Expected":145.43,"Rank in p.value_classic":4279,"p.value_elim":0.9995,"p.value_classic":0.84989,"genes":"ACOD1,AGT,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDC6,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CIITA,CTNS,CX3CR1,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DTNBP1,DTX3L,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GCH1,GHRL,GTPBP1,HBEGF,HCAR2,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IL15,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LAMP3,LBH,LRP5,LRRK2,LYN,MAD2L1,MAF,MAFF,MEFV,MERTK,MIR503,MMP9,MUC1,MVP,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OPTN,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE3B,PID1,PIWIL4,PKIB,PLEK,PML,PPM1E,PTGER4,RAPGEF2,RELB,RMI2,SAMD4A,SBNO2,SERPING1,SLAMF1,SLAMF8,SLC11A1,SOCS1,STAP1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0031324","Term":"negative regulation of cellular metabolic process","Annotated":2200,"Significant":124,"Expected":132.87,"Rank in p.value_classic":4146,"p.value_elim":0.99955,"p.value_classic":0.82068,"genes":"ACOD1,AGT,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDC6,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CIITA,CTNS,CX3CR1,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DTNBP1,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GCH1,GHRL,GTPBP1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LBH,LRP5,LRRK2,LYN,MAF,MAFF,MEFV,MERTK,MIR503,MUC1,MVP,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PID1,PIWIL4,PKIB,PLEK,PML,PPM1E,PTGER4,RAPGEF2,RELB,RMI2,SAMD4A,SBNO2,SLAMF1,SLC11A1,SOCS1,STAP1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0051028","Term":"mRNA transport","Annotated":124,"Significant":1,"Expected":7.49,"Rank in p.value_classic":4944,"p.value_elim":0.99957,"p.value_classic":0.99957,"genes":"MVP"} {"GO.ID":"GO:0051168","Term":"nuclear export","Annotated":163,"Significant":2,"Expected":9.84,"Rank in p.value_classic":4945,"p.value_elim":0.99957,"p.value_classic":0.99958,"genes":"EGR2,IFI27"} {"GO.ID":"GO:0072594","Term":"establishment of protein localization to organelle","Annotated":412,"Significant":11,"Expected":24.88,"Rank in p.value_classic":4946,"p.value_elim":0.99958,"p.value_classic":0.9996,"genes":"ABLIM3,APPL2,CDK1,IFT122,JAK2,KPNA5,LAMP3,LAMP5,LRRK2,PML,ZC3H12A"} {"GO.ID":"GO:0032259","Term":"methylation","Annotated":228,"Significant":4,"Expected":13.77,"Rank in p.value_classic":4947,"p.value_elim":0.99959,"p.value_classic":0.9996,"genes":"ARMT1,HELLS,TMT1B,TYMS"} {"GO.ID":"GO:0006352","Term":"DNA-templated transcription initiation","Annotated":164,"Significant":2,"Expected":9.9,"Rank in p.value_classic":4948,"p.value_elim":0.99959,"p.value_classic":0.9996,"genes":"E2F2,PADI2"} {"GO.ID":"GO:0010605","Term":"negative regulation of macromolecule metabolic process","Annotated":2230,"Significant":125,"Expected":134.68,"Rank in p.value_classic":4246,"p.value_elim":0.99964,"p.value_classic":0.83981,"genes":"ACOD1,AGT,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,BACH1,BANK1,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BRCA1,BTN2A2,CARD16,CD274,CD28,CD38,CD83,CDC6,CDK1,CDT1,CEACAM1,CENPF,CHAC1,CIITA,CX3CR1,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DTNBP1,DTX3L,E2F1,E2F8,EDN1,ETV7,GBP1,GBP7,GHRL,GTPBP1,HBEGF,HELLS,HESX1,HGF,HLA-DRB1,HLA-F,HSBP1L1,IDO1,IFI27,IL12A,IQGAP3,IRF1,IRF7,JAK3,KLF4,LAG3,LAMP3,LBH,LRP5,LRRK2,LYN,MAD2L1,MAF,MAFF,MEFV,MERTK,MIR503,MMP9,MUC1,MVP,MYOZ2,NLRP12,NMI,NOD2,NR4A3,OAS3,OPTN,OVOL1,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PID1,PIWIL4,PKIB,PML,PPM1E,PTGER4,RELB,RMI2,SAMD4A,SBNO2,SERPING1,SLAMF1,SLC11A1,SOCS1,STAT1,TAL1,TBX21,TDRD9,TFEC,TLR8,TNFRSF21,TRIM22,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF608,ZNFX1"} {"GO.ID":"GO:0006996","Term":"organelle organization","Annotated":3108,"Significant":176,"Expected":187.71,"Rank in p.value_classic":4288,"p.value_elim":0.99972,"p.value_classic":0.85394,"genes":"ABLIM3,AIFM2,AMOT,ANK2,ANLN,ANTXR1,ASB2,ATF5,ATP13A2,ATP8B1,AURKB,BCL2A1,BCL2L11,BCL6,BIRC5,BRCA1,BUB1B,CALCOCO2,CCDC170,CCL13,CCL7,CCNE2,CCNF,CD28,CDC45,CDC6,CDCA5,CDH5,CDK1,CDKL1,CDS1,CDT1,CELSR1,CENPF,CENPK,CHMP4C,CHTF18,CIBAR1,CXADR,CYLD,DAZL,DMC1,DNAAF1,DNM1,DSCC1,DTNBP1,DYNLT1,EDN1,EME1,EML4,EPAS1,ERC2,ESCO2,EXO1,F2RL3,FAM107A,FEN1,FGD5,FMNL2,FRMD3,FSCN1,GCH1,GHRL,GINS1,GINS2,GOLM1,HGF,HJURP,HLA-DRB1,HORMAD1,IFIT2,IFT122,INA,IQGAP3,ITGB5,JAK2,KCNJ10,KIF11,KIF18B,KIF23,LIMK2,LRP5,LRRC61,LRRK2,MAD2L1,MAP1LC3C,MARCKSL1,MCM2,MCM4,MCM5,MCM6,MCM7,MEIKIN,MICAL2,MKI67,MMP9,MRAS,MSRB1,MTSS1,MYBL2,MYO7B,MYOZ2,NCAPG,NCAPG2,NCAPH,NDC80,NOD2,NPM2,NRP1,NUF2,NUSAP1,OCA2,OIP5,ONECUT2,OPTN,P2RX7,PARP3,PCLAF,PID1,PKIB,PKMYT1,PLAAT3,PLEK,PMAIP1,PML,PNPLA3,PPM1E,PRC1,PRRT2,PSTPIP2,PTGER4,PXN,PYROXD2,RAB20,RAD54B,RAD54L,RALB,RECQL4,REEP1,RMI2,RNF213,RUFY4,S100A10,S1PR1,SCIN,SCO2,SLAMF1,SLAMF8,SLC4A7,SNX10,SPC24,SPC25,SPTBN4,STAT2,STMN1,STX11,STX1A,SYNE1,SYT1,TACC2,TAL1,TDRD9,TMSB10,TNFSF10,TOP2A,TRDN,TSPAN32,TYMP,UHRF1,USP6NL,WDR62,WEE1,XIRP1,XRCC2,XRN1,ZWINT"} {"GO.ID":"GO:0006605","Term":"protein targeting","Annotated":293,"Significant":6,"Expected":17.7,"Rank in p.value_classic":4949,"p.value_elim":0.99972,"p.value_classic":0.99973,"genes":"ABLIM3,GBP5,LRRK2,NCF1,RTP4,ZDHHC19"} {"GO.ID":"GO:0006354","Term":"DNA-templated transcription elongation","Annotated":132,"Significant":1,"Expected":7.97,"Rank in p.value_classic":4950,"p.value_elim":0.99974,"p.value_classic":0.99974,"genes":"EPOP"} {"GO.ID":"GO:2001141","Term":"regulation of RNA biosynthetic process","Annotated":2776,"Significant":130,"Expected":167.66,"Rank in p.value_classic":4953,"p.value_elim":0.99975,"p.value_classic":0.99978,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PARP10,PARP14,PARP9,PID1,PIM1,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WWP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0010608","Term":"post-transcriptional regulation of gene expression","Annotated":498,"Significant":14,"Expected":30.08,"Rank in p.value_classic":4951,"p.value_elim":0.99976,"p.value_classic":0.99977,"genes":"BANK1,CCL5,CD28,DAZL,DHFR,E2F1,MIR503,PARP9,PIWIL4,SAMD4A,SLC11A1,TYMS,XRN1,ZC3H12A"} {"GO.ID":"GO:0008033","Term":"tRNA processing","Annotated":134,"Significant":1,"Expected":8.09,"Rank in p.value_classic":4952,"p.value_elim":0.99977,"p.value_classic":0.99977,"genes":"KARS1"} {"GO.ID":"GO:0006119","Term":"oxidative phosphorylation","Annotated":137,"Significant":1,"Expected":8.27,"Rank in p.value_classic":4954,"p.value_elim":0.99981,"p.value_classic":0.99981,"genes":"CDK1"} {"GO.ID":"GO:0048193","Term":"Golgi vesicle transport","Annotated":275,"Significant":5,"Expected":16.61,"Rank in p.value_classic":4955,"p.value_elim":0.99983,"p.value_classic":0.99984,"genes":"DOP1A,LRRK2,OPTN,TAPBP,VAMP5"} {"GO.ID":"GO:0044085","Term":"cellular component biogenesis","Annotated":2826,"Significant":149,"Expected":170.68,"Rank in p.value_classic":4782,"p.value_elim":0.99985,"p.value_classic":0.9773,"genes":"ABLIM3,AGT,AIM2,ANK2,ANLN,ANTXR1,APPL2,ASB2,ASIC1,ATP13A2,ATP8B1,AURKB,B2M,BAZ1A,BCL2L11,BIRC5,BRCA1,CASP4,CD40,CD74,CDC45,CDH5,CDK1,CDKL1,CDS1,CDT1,CENPF,CENPK,CHAF1B,CHMP4C,CIBAR1,COLQ,COMP,CTNS,CYLD,DAB2,DMC1,DNAAF1,DNM1,EDN1,EPHB3,ERC2,EXO1,FAM107A,FAS,FGD5,FSCN1,GABRA3,GBP1,GBP2,GBP5,GCH1,GHRL,GJD3,GLUL,GSDMD,H2BC21,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,HORMAD1,ICAM1,IFIH1,IFT122,IQGAP3,ISG20,ITGB5,JAK2,KCNJ10,KCNJ2,KCTD14,KIF11,KIF23,LGI2,LIMK2,LRRC61,LRRK2,MAP1LC3C,MARVELD2,MCM2,MDGA1,MEFV,MSRB1,MTSS1,MYBL2,MYO7B,MYOZ2,NDC80,NRCAM,NRP1,OIP5,ONECUT2,P2RX7,PLEK,PML,POMP,PPM1E,PRC1,PRRT2,PSTPIP2,PTGER4,PXN,RAB20,RALB,RAPGEF2,REPS2,RIPK2,RNF213,RRM2,RUFY4,S100A10,S1PR1,SCIN,SCO2,SNX10,SOAT1,SPTBN4,SSBP3,STAP1,STEAP4,STMN1,STX1A,SYT1,TAL1,TAPBP,TAPBPL,THBS2,TIFA,TK1,TMSB10,TRABD2A,TRIM31,UBD,UHRF1,WARS1,WDR62,ZC3H12A"} {"GO.ID":"GO:0071840","Term":"cellular component organization or biogenesis","Annotated":5605,"Significant":331,"Expected":338.52,"Rank in p.value_classic":3809,"p.value_elim":0.99985,"p.value_classic":0.7235,"genes":"ABCB1,ABLIM3,ADAM8,ADAMTS15,AGT,AIFM2,AIM2,AMOT,ANK2,ANLN,ANO4,ANTXR1,APPL2,ASB2,ASIC1,ATF5,ATP13A2,ATP1B2,ATP8B1,AURKB,B2M,BAZ1A,BCL2A1,BCL2L11,BCL6,BIRC5,BRCA1,BUB1B,C1QB,C2,C21orf91,C3,C4A,C4B,CALCOCO2,CAMK2D,CASP4,CASP7,CBLN3,CCDC170,CCL13,CCL7,CCNE2,CCNF,CD28,CD300LF,CD38,CD40,CD74,CDC45,CDC6,CDCA5,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CELSR1,CENPF,CENPK,CHAF1B,CHMP4C,CHTF18,CIBAR1,CISH,COL23A1,COL9A2,COLEC12,COLGALT2,COLQ,COMP,CTNS,CTSL,CTSS,CTTNBP2,CX3CR1,CXADR,CXCL10,CXCL9,CYLD,DAB1,DAB2,DAZL,DEPTOR,DHFR,DLGAP3,DLL1,DMC1,DNAAF1,DNM1,DSCC1,DTNBP1,DTX3L,DYNLT1,DYSF,EDN1,EGR2,EME1,EML4,ENPP2,EPAS1,EPHB3,EPOP,ERC2,ERCC6L,ESCO2,EXO1,F2RL3,FAM107A,FAS,FCN1,FEN1,FGD5,FMNL2,FRMD3,FSCN1,FSTL4,GABRA3,GBP1,GBP2,GBP5,GCH1,GHRL,GINS1,GINS2,GJD3,GLDN,GLUL,GOLM1,GRAMD1B,GRIN3A,GSDMD,H2BC21,HAVCR1,HBEGF,HELLS,HGF,HJURP,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-G,HORMAD1,ICAM1,IFIH1,IFIT2,IFT122,IL15,IL15RA,INA,IQGAP3,IRF4,ISG20,ITGB5,JADE2,JAK2,KCNJ10,KCNJ2,KCTD14,KIF11,KIF18B,KIF23,KIF26A,KLF4,KREMEN1,LGI2,LIMK2,LPL,LRP5,LRRC61,LRRK2,LYN,MAD2L1,MAP1LC3C,MARCKSL1,MARVELD2,MCM2,MCM4,MCM5,MCM6,MCM7,MDGA1,MEFV,MEIKIN,MERTK,MICAL2,MKI67,MMP25,MMP9,MRAS,MSRB1,MTSS1,MYBL2,MYO7B,MYOF,MYOZ2,NCAPG,NCAPG2,NCAPH,NDC80,NECAB2,NOD2,NPM2,NPR1,NRCAM,NRN1,NRP1,NUF2,NUSAP1,NYAP2,OCA2,OIP5,OLFML2B,OLIG1,ONECUT2,OPTN,P2RX7,PADI2,PARP10,PARP3,PCDHGC3,PCLAF,PID1,PKIB,PKMYT1,PLAAT3,PLEK,PLSCR1,PLSCR4,PLXNA2,PMAIP1,PML,PNPLA3,POMP,PPM1E,PRC1,PRRT2,PSTPIP2,PTGER4,PXN,PYROXD2,RAB20,RAD54B,RAD54L,RALB,RAPGEF2,RASGRF1,RECQL4,REEP1,REPS2,RIPK2,RMI2,RNF213,RRM2,RTN4RL1,RTP4,RUFY4,RXFP1,S100A10,S1PR1,SCARF1,SCIN,SCO2,SDC2,SEMA6B,SLAMF1,SLAMF8,SLC11A1,SLC12A3,SLC4A7,SNX10,SOAT1,SOX17,SPC24,SPC25,SPTBN4,SSBP3,STAP1,STAT2,STEAP4,STMN1,STX11,STX1A,SYNE1,SYT1,TACC2,TAL1,TAPBP,TAPBPL,TDRD9,TGM2,THBS2,TIFA,TK1,TMSB10,TNFAIP6,TNFAIP8L3,TNFRSF21,TNFSF10,TONSL,TOP2A,TRABD2A,TRDN,TRIM31,TSPAN32,TYMP,UBD,UHRF1,USP6NL,WARS1,WDR62,WEE1,XIRP1,XKR6,XRCC2,XRN1,ZC3H12A,ZNFX1,ZWINT"} {"GO.ID":"GO:0030705","Term":"cytoskeleton-dependent intracellular transport","Annotated":186,"Significant":2,"Expected":11.23,"Rank in p.value_classic":4957,"p.value_elim":0.99988,"p.value_classic":0.99989,"genes":"DTNBP1,IFT122"} {"GO.ID":"GO:0006355","Term":"regulation of DNA-templated transcription","Annotated":2760,"Significant":127,"Expected":166.69,"Rank in p.value_classic":4958,"p.value_elim":0.99989,"p.value_classic":0.9999,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PARP10,PARP14,PARP9,PID1,PIM1,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WWP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006886","Term":"intracellular protein transport","Annotated":620,"Significant":18,"Expected":37.45,"Rank in p.value_classic":4960,"p.value_elim":0.99992,"p.value_classic":0.99992,"genes":"APPL2,ARL4C,ATP13A2,CD74,CDK1,DERL3,EGR2,IFI27,JAK2,KPNA5,LRRK2,MAP1LC3C,PML,RAB20,SNX10,STX11,STX1A,ZC3H12A"} {"GO.ID":"GO:0006399","Term":"tRNA metabolic process","Annotated":198,"Significant":2,"Expected":11.96,"Rank in p.value_classic":4963,"p.value_elim":0.99994,"p.value_classic":0.99994,"genes":"KARS1,WARS1"} {"GO.ID":"GO:0006357","Term":"regulation of transcription by RNA polymerase II","Annotated":2068,"Significant":88,"Expected":124.9,"Rank in p.value_classic":4964,"p.value_elim":0.99995,"p.value_classic":0.99996,"genes":"ABLIM3,ASCL2,ATF3,ATF5,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BMAL2,BRCA1,CAMK2D,CASZ1,CD28,CD40,CDK1,CIITA,CXCL10,DAB2,DLL1,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,IFI27,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KLF4,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NFXL1,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PARP9,PID1,PLSCR1,RELB,RIPK2,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TFEC,TLR7,TNFSF8,TOP2A,TOX2,UHRF1,ZC3H12A,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0032774","Term":"RNA biosynthetic process","Annotated":2898,"Significant":132,"Expected":175.03,"Rank in p.value_classic":4967,"p.value_elim":0.99996,"p.value_classic":0.99996,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP9,PID1,PIM1,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WWP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0043414","Term":"macromolecule methylation","Annotated":161,"Significant":1,"Expected":9.72,"Rank in p.value_classic":4966,"p.value_elim":0.99996,"p.value_classic":0.99996,"genes":"HELLS"} {"GO.ID":"GO:0006351","Term":"DNA-templated transcription","Annotated":2870,"Significant":129,"Expected":173.34,"Rank in p.value_classic":4968,"p.value_elim":0.99998,"p.value_classic":0.99998,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP9,PID1,PIM1,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WWP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006518","Term":"peptide metabolic process","Annotated":780,"Significant":23,"Expected":47.11,"Rank in p.value_classic":4970,"p.value_elim":0.99998,"p.value_classic":0.99999,"genes":"BANK1,CCL5,CD28,CHAC1,CTNS,CTSL,DAZL,DHFR,DNPEP,ERAP2,GGT5,GSAP,GSTK1,GTPBP1,KARS1,MIR503,NOD2,PIWIL4,SAMD4A,TAPBP,TYMS,WARS1,XRN1"} {"GO.ID":"GO:0043603","Term":"amide metabolic process","Annotated":1008,"Significant":33,"Expected":60.88,"Rank in p.value_classic":4971,"p.value_elim":0.99999,"p.value_classic":0.99999,"genes":"ACOT4,ACSL1,BANK1,CCL5,CD28,CHAC1,CTNS,CTSL,DAZL,DGAT2,DHFR,DNPEP,ERAP2,GGT5,GSAP,GSTK1,GTPBP1,KARS1,MIR503,MTHFD2,NAAA,NOD2,P2RX7,PDK4,PIWIL4,PLAAT3,PLAAT4,SAMD4A,SGPL1,TAPBP,TYMS,WARS1,XRN1"} {"GO.ID":"GO:0080090","Term":"regulation of primary metabolic process","Annotated":4590,"Significant":245,"Expected":277.22,"Rank in p.value_classic":4882,"p.value_elim":0.99999,"p.value_classic":0.99438,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGT,AIM2,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLSPN,CSF1,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPOP,ESCO2,ETV7,FAM107A,FAM20A,FAS,FAXDC2,GCH1,GOLM1,GRAMD4,GSAP,GTPBP1,HBEGF,HCAR2,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL12A,IL15,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,LACTB,LAMP3,LBH,LILRA2,LIMK2,LITAF,LRP5,LRRK2,LYN,MAD2L1,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MEFV,MICAL2,MIR503,MMD,MMP9,MUC1,MVP,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PARP10,PARP14,PARP3,PARP9,PDE3B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLEK,PLSCR1,PMAIP1,PML,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF213,S100A10,S1PR1,SAMD4A,SBNO2,SEPTIN4,SERPING1,SLC11A1,SLC2A6,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAT1,STAT2,SUCNR1,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TICRR,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TRABD2A,TRIM22,TRIM31,TSPAN15,TTC39B,TYMS,UHRF1,VEGFC,WARS1,WEE1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006366","Term":"transcription by RNA polymerase II","Annotated":2170,"Significant":90,"Expected":131.06,"Rank in p.value_classic":4972,"p.value_elim":0.99999,"p.value_classic":0.99999,"genes":"ABLIM3,ASCL2,ATF3,ATF5,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BMAL2,BRCA1,CAMK2D,CASZ1,CD28,CD40,CDK1,CIITA,CXCL10,DAB2,DLL1,E2F1,E2F2,E2F8,EBF4,EDN1,EGR2,EPAS1,EPOP,ETV7,HESX1,HGF,HIVEP2,IFI27,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KLF4,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NFXL1,NLRC5,NOD2,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP9,PID1,PLSCR1,RELB,RIPK2,S100A10,S1PR1,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TFEC,TLR7,TNFSF8,TOP2A,TOX2,UHRF1,ZC3H12A,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0009060","Term":"aerobic respiration","Annotated":185,"Significant":1,"Expected":11.17,"Rank in p.value_classic":4973,"p.value_elim":0.99999,"p.value_classic":0.99999,"genes":"CDK1"} {"GO.ID":"GO:0051171","Term":"regulation of nitrogen compound metabolic process","Annotated":4493,"Significant":239,"Expected":271.36,"Rank in p.value_classic":4892,"p.value_elim":0.99999,"p.value_classic":0.99477,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGT,AIM2,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLSPN,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPOP,ESCO2,ETV7,FAM107A,FAM20A,FAS,FAXDC2,GCH1,GRAMD4,GSAP,GTPBP1,HBEGF,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL12A,IL15,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LAMP3,LBH,LILRA2,LIMK2,LITAF,LRP5,LRRK2,LYN,MAD2L1,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MEFV,MICAL2,MIR503,MMD,MMP9,MUC1,MVP,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PARP10,PARP14,PARP3,PARP9,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLSCR1,PMAIP1,PML,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PYHIN1,RALB,RAPGEF2,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,S100A10,S1PR1,SAMD4A,SBNO2,SEPTIN4,SERPING1,SLC11A1,SLC2A6,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAT1,STAT2,SUCNR1,TAL1,TANK,TBX21,TESC,TFEC,TICAM2,TICRR,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TRABD2A,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,VEGFC,WARS1,WEE1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0019438","Term":"aromatic compound biosynthetic process","Annotated":3348,"Significant":160,"Expected":202.2,"Rank in p.value_classic":4956,"p.value_elim":0.99999,"p.value_classic":0.99988,"genes":"ABLIM3,ACOD1,ACSL1,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CHTF18,CIITA,CMPK2,CTNS,CXCL10,CYLD,DAB2,DHFR,DLL1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,GCH1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPR1,NR4A3,OCA2,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PID1,PIM1,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RRM2,S100A10,S1PR1,SBNO2,SLC11A1,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TK1,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UHRF1,VPS9D1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0051252","Term":"regulation of RNA metabolic process","Annotated":3044,"Significant":135,"Expected":183.84,"Rank in p.value_classic":4974,"p.value_elim":0.99999,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DAZL,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,GTPBP1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,PARP10,PARP14,PARP9,PID1,PIM1,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SAMD4A,SBNO2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WWP1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0043043","Term":"peptide biosynthetic process","Annotated":643,"Significant":16,"Expected":38.83,"Rank in p.value_classic":4975,"p.value_elim":0.99999,"p.value_classic":1,"genes":"BANK1,CCL5,CD28,CHAC1,DAZL,DHFR,GGT5,GTPBP1,KARS1,MIR503,NOD2,PIWIL4,SAMD4A,TYMS,WARS1,XRN1"} {"GO.ID":"GO:0034654","Term":"nucleobase-containing compound biosynthetic process","Annotated":3281,"Significant":155,"Expected":198.16,"Rank in p.value_classic":4961,"p.value_elim":1,"p.value_classic":0.99992,"genes":"ABLIM3,ACOD1,ACSL1,ADORA3,AGT,AIM2,AK1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CHTF18,CIITA,CMPK2,CXCL10,CYLD,DAB2,DLL1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,GCH1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPR1,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PID1,PIM1,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RRM2,S100A10,S1PR1,SBNO2,SLC11A1,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TK1,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UHRF1,VPS9D1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:1901362","Term":"organic cyclic compound biosynthetic process","Annotated":3458,"Significant":164,"Expected":208.85,"Rank in p.value_classic":4962,"p.value_elim":1,"p.value_classic":0.99994,"genes":"ABLIM3,ACOD1,ACSL1,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CHTF18,CIITA,CMPK2,CTNS,CXCL10,CYLD,CYP1A1,DAB2,DHFR,DLL1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FAXDC2,GCH1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,HSD3B7,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPR1,NR4A3,OCA2,OLIG1,ONECUT2,OSBPL6,OSM,OVOL1,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PID1,PIM1,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RRM2,S100A10,S1PR1,SBNO2,SLC11A1,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TK1,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UHRF1,VPS9D1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:1901566","Term":"organonitrogen compound biosynthetic process","Annotated":1526,"Significant":55,"Expected":92.16,"Rank in p.value_classic":4976,"p.value_elim":1,"p.value_classic":1,"genes":"ACSL1,AK1,ALAS1,BANK1,CCL5,CD28,CD80,CDS1,CHAC1,CMPK2,DAZL,DERL3,DHFR,DSE,GAL3ST4,GALNT18,GCH1,GCNT3,GGT5,GLUL,GTPBP1,HBEGF,IDO1,IDO2,IL15,JAK3,KARS1,KLF4,LILRA2,MIR503,NECAB2,NOD2,NPR1,P2RX7,PARP10,PARP9,PCYT1A,PDK4,PID1,PIWIL4,PLSCR1,PRTFDC1,SAMD4A,SAT1,SERINC5,SLC4A7,SOAT1,TK1,TMTC1,TYMS,VPS9D1,WARS1,XRN1,XYLT1,ZDHHC19"} {"GO.ID":"GO:0018130","Term":"heterocycle biosynthetic process","Annotated":3347,"Significant":157,"Expected":202.14,"Rank in p.value_classic":4965,"p.value_elim":1,"p.value_classic":0.99996,"genes":"ABLIM3,ACOD1,ACSL1,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CHTF18,CIITA,CMPK2,CXCL10,CYLD,DAB2,DHFR,DLL1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,GCH1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPR1,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PID1,PIM1,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RRM2,S100A10,S1PR1,SBNO2,SLC11A1,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TK1,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UHRF1,VPS9D1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0016072","Term":"rRNA metabolic process","Annotated":260,"Significant":2,"Expected":15.7,"Rank in p.value_classic":4977,"p.value_elim":1,"p.value_classic":1,"genes":"ISG20,XRN1"} {"GO.ID":"GO:0019219","Term":"regulation of nucleobase-containing compound metabolic process","Annotated":3315,"Significant":157,"Expected":200.21,"Rank in p.value_classic":4959,"p.value_elim":1,"p.value_classic":0.99992,"genes":"ABLIM3,ACOD1,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC6,CDCA7,CDK1,CDT1,CENPF,CHTF18,CIITA,CXCL10,CYLD,DAB2,DAZL,DLL1,DSCC1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ESCO2,ETV7,GCH1,GTPBP1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MUC1,MYBL2,MYOZ2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PARP10,PARP14,PARP3,PARP9,PDK4,PID1,PIM1,PKIB,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RMI2,RNF141,S100A10,S1PR1,SAMD4A,SBNO2,SLC11A1,SLC2A6,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TICRR,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WEE1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0031326","Term":"regulation of cellular biosynthetic process","Annotated":4169,"Significant":241,"Expected":251.79,"Rank in p.value_classic":4129,"p.value_elim":1,"p.value_classic":0.81274,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CTNS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FCN1,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLEK,PLSCR1,PML,PTGER4,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0043604","Term":"amide biosynthetic process","Annotated":753,"Significant":19,"Expected":45.48,"Rank in p.value_classic":4979,"p.value_elim":1,"p.value_classic":1,"genes":"ACSL1,BANK1,CCL5,CD28,CHAC1,DAZL,DHFR,GGT5,GTPBP1,KARS1,MIR503,NOD2,P2RX7,PDK4,PIWIL4,SAMD4A,TYMS,WARS1,XRN1"} {"GO.ID":"GO:0006364","Term":"rRNA processing","Annotated":220,"Significant":1,"Expected":13.29,"Rank in p.value_classic":4980,"p.value_elim":1,"p.value_classic":1,"genes":"ISG20"} {"GO.ID":"GO:0010556","Term":"regulation of macromolecule biosynthetic process","Annotated":4071,"Significant":235,"Expected":245.87,"Rank in p.value_classic":4142,"p.value_elim":1,"p.value_classic":0.81602,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FCN1,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,PTGER4,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0009889","Term":"regulation of biosynthetic process","Annotated":4194,"Significant":241,"Expected":253.3,"Rank in p.value_classic":4249,"p.value_elim":1,"p.value_classic":0.84287,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CTNS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FCN1,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLEK,PLSCR1,PML,PTGER4,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0019222","Term":"regulation of metabolic process","Annotated":5344,"Significant":314,"Expected":322.75,"Rank in p.value_classic":3929,"p.value_elim":1,"p.value_classic":0.75476,"genes":"ABLIM3,ACOD1,ACSL1,ADAM8,ADORA3,AGR2,AGT,AIM2,AMER1,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CALCOCO2,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,COMP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DRAM1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPOP,ESCO2,ETV7,FAM107A,FAM20A,FAS,FAXDC2,FCN1,G0S2,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GOLM1,GRAMD4,GSAP,GSDMD,GTPBP1,HBEGF,HCAR2,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LACTB,LAG3,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAD2L1,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MUC1,MVP,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE3B,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLEK,PLSCR1,PMAIP1,PML,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF213,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SEPTIN4,SERPING1,SESN3,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC2A6,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAP1,STAT1,STAT2,SUCNR1,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TICRR,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRABD2A,TRIM17,TRIM22,TRIM31,TSPAN15,TTC39B,TYMS,TYRO3,UHRF1,VEGFC,WARS1,WEE1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0006412","Term":"translation","Annotated":620,"Significant":13,"Expected":37.45,"Rank in p.value_classic":4981,"p.value_elim":1,"p.value_classic":1,"genes":"BANK1,CCL5,CD28,DAZL,DHFR,GTPBP1,KARS1,MIR503,PIWIL4,SAMD4A,TYMS,WARS1,XRN1"} {"GO.ID":"GO:0060255","Term":"regulation of macromolecule metabolic process","Annotated":4929,"Significant":292,"Expected":297.69,"Rank in p.value_classic":3632,"p.value_elim":1,"p.value_classic":0.67955,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,AMER1,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,COMP,CSF1,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DSCC1,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPOP,ESCO2,ETV7,FAM107A,FAM20A,FAS,FAXDC2,FCN1,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GRAMD4,GSAP,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAD2L1,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MUC1,MVP,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLSCR1,PMAIP1,PML,PPM1E,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SEPTIN4,SERPING1,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAP1,STAT1,STAT2,SUCNR1,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TICRR,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF18,TNFSF8,TOP2A,TOX2,TRABD2A,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,VEGFC,WARS1,WEE1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0010468","Term":"regulation of gene expression","Annotated":3959,"Significant":225,"Expected":239.11,"Rank in p.value_classic":4374,"p.value_elim":1,"p.value_classic":0.87867,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,ANK2,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FCN1,G6PC1,GBP1,GBP5,GBP7,GHRL,GSDMD,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCF1,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PID1,PIM1,PIWIL4,PLSCR1,PML,PTGER4,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TYMS,UHRF1,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0042254","Term":"ribosome biogenesis","Annotated":311,"Significant":2,"Expected":18.78,"Rank in p.value_classic":4988,"p.value_elim":1,"p.value_classic":1,"genes":"GLUL,ISG20"} {"GO.ID":"GO:0034470","Term":"ncRNA processing","Annotated":411,"Significant":4,"Expected":24.82,"Rank in p.value_classic":4991,"p.value_elim":1,"p.value_classic":1,"genes":"ISG20,KARS1,PIWIL4,TDRD9"} {"GO.ID":"GO:0031323","Term":"regulation of cellular metabolic process","Annotated":4939,"Significant":286,"Expected":298.29,"Rank in p.value_classic":4213,"p.value_elim":1,"p.value_classic":0.8335,"genes":"ABLIM3,ACOD1,ADAM8,ADORA3,AGR2,AGT,AIM2,ANK2,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C3,CALCOCO2,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC6,CDCA7,CDH5,CDK1,CDKN2C,CDT1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,CLSPN,COMP,CSF1,CTNS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DEPTOR,DHFR,DLL1,DRAM1,DSCC1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,ENPP2,EPAS1,EPOP,ESCO2,ETV7,FAM20A,FAS,FAXDC2,FCN1,G6PC1,GBP1,GBP5,GBP7,GCH1,GHRL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LIMK2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MUC1,MVP,MYBL2,MYOZ2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLEK,PLSCR1,PML,PPM1E,PTGER4,PYHIN1,RALB,RAPGEF2,RELB,RHEBL1,RIPK2,RMI2,RNF141,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SESN3,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC2A6,SLC45A3,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TICAM2,TICRR,TIFAB,TLR5,TLR7,TLR8,TMEM119,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TPCN1,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,TYRO3,UHRF1,VEGFC,WARS1,WEE1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0034660","Term":"ncRNA metabolic process","Annotated":600,"Significant":9,"Expected":36.24,"Rank in p.value_classic":4994,"p.value_elim":1,"p.value_classic":1,"genes":"AGT,ISG20,KARS1,KLF4,PIWIL4,TDRD9,WARS1,XRN1,ZC3H12A"} {"GO.ID":"GO:0046907","Term":"intracellular transport","Annotated":1249,"Significant":33,"Expected":75.43,"Rank in p.value_classic":4996,"p.value_elim":1,"p.value_classic":1,"genes":"APPL2,ARL4C,ATP13A2,ATP6V0D2,CD74,CDK1,CHMP4C,DAB2,DERL3,DOP1A,DTNBP1,DTX3L,EGR2,GRAMD1B,IFI27,IFT122,IGF2R,ITSN1,JAK2,KPNA5,LMTK2,LRRK2,MAP1LC3C,PML,RAB20,REPS2,RHOBTB3,SNX10,STX11,STX1A,TAP1,TAP2,ZC3H12A"} {"GO.ID":"GO:0016071","Term":"mRNA metabolic process","Annotated":680,"Significant":10,"Expected":41.07,"Rank in p.value_classic":4999,"p.value_elim":1,"p.value_classic":1,"genes":"ADARB2,DAZL,E2F1,EPAS1,GTPBP1,S100A10,SAMD4A,SLC11A1,XRN1,ZC3H12A"} {"GO.ID":"GO:0044271","Term":"cellular nitrogen compound biosynthetic process","Annotated":3963,"Significant":172,"Expected":239.35,"Rank in p.value_classic":4992,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ACSL1,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CHAC1,CHTF18,CIITA,CMPK2,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,GCH1,GGT5,GTPBP1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,JADE2,JAK2,KARS1,KLF4,KLRK1,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NPR1,NR4A3,OLIG1,ONECUT2,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SAT1,SBNO2,SLC11A1,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TESC,TFEC,TICAM2,TK1,TLR7,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UHRF1,VPS9D1,WARS1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0022613","Term":"ribonucleoprotein complex biogenesis","Annotated":457,"Significant":2,"Expected":27.6,"Rank in p.value_classic":5003,"p.value_elim":1,"p.value_classic":1,"genes":"GLUL,ISG20"} {"GO.ID":"GO:0090304","Term":"nucleic acid metabolic process","Annotated":4277,"Significant":196,"Expected":258.31,"Rank in p.value_classic":4983,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ADARB2,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CIITA,CLSPN,CXCL10,CYLD,DAB2,DAZL,DLL1,DMC1,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,EPAS1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FBXO6,FEN1,GCH1,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,ORC1,OSM,OVOL1,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PYHIN1,RAD54B,RAD54L,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,S100A10,S1PR1,SAMD4A,SBNO2,SIDT2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TYMS,UBE2T,UHRF1,UNG,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:1901360","Term":"organic cyclic compound metabolic process","Annotated":5067,"Significant":239,"Expected":306.02,"Rank in p.value_classic":4985,"p.value_elim":1,"p.value_classic":1,"genes":"ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADARB2,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CIITA,CLSPN,CMPK2,CTNS,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DGAT2,DHFR,DHRS9,DLL1,DMC1,DPYS,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,ENPP4,EPAS1,EPHX1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FAXDC2,FBXO6,FEN1,G6PC1,GCH1,GIMAP7,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,HSD11B1,HSD3B7,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,LRRK2,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MTHFD2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NPR1,NR4A3,OAS2,OAS3,OCA2,OLIG1,ONECUT2,ORC1,OSBPL6,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAD54B,RAD54L,RAPGEF2,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SBNO2,SCARF1,SGPL1,SIDT2,SLC11A1,SLC16A10,SLC2A6,SLC4A7,SOAT1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TTC39B,TYMP,TYMS,UBE2T,UHRF1,UNG,VPS9D1,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006725","Term":"cellular aromatic compound metabolic process","Annotated":4899,"Significant":228,"Expected":295.88,"Rank in p.value_classic":4987,"p.value_elim":1,"p.value_classic":1,"genes":"ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADARB2,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CIITA,CLSPN,CMPK2,CTNS,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DGAT2,DHFR,DLL1,DMC1,DPYS,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,ENPP4,EPAS1,EPHX1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FBXO6,FEN1,G6PC1,GCH1,GIMAP7,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,LRRK2,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MTHFD2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NPR1,NR4A3,OAS2,OAS3,OCA2,OLIG1,ONECUT2,ORC1,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAD54B,RAD54L,RAPGEF2,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SBNO2,SIDT2,SLC11A1,SLC16A10,SLC2A6,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TYMP,TYMS,UBE2T,UHRF1,UNG,VPS9D1,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006397","Term":"mRNA processing","Annotated":451,"Significant":1,"Expected":27.24,"Rank in p.value_classic":5005,"p.value_elim":1,"p.value_classic":1,"genes":"ADARB2"} {"GO.ID":"GO:0016070","Term":"RNA metabolic process","Annotated":3784,"Significant":146,"Expected":228.54,"Rank in p.value_classic":5004,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ADARB2,ADORA3,AGT,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CDCA7,CDK1,CENPF,CIITA,CXCL10,CYLD,DAB2,DAZL,DLL1,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,FEN1,GTPBP1,HESX1,HGF,HIVEP2,HLA-DRB1,HSBP1L1,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,MAF,MAFF,MAML3,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,PADI2,PARP10,PARP14,PARP9,PID1,PIM1,PIWIL4,PLSCR1,PML,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,S100A10,S1PR1,SAMD4A,SBNO2,SIDT2,SLC11A1,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM22,TRIM31,UHRF1,WARS1,WWP1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0046483","Term":"heterocycle metabolic process","Annotated":4880,"Significant":225,"Expected":294.73,"Rank in p.value_classic":4990,"p.value_elim":1,"p.value_classic":1,"genes":"ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADARB2,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CIITA,CLSPN,CMPK2,CTNS,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DGAT2,DHFR,DLL1,DMC1,DPYS,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,ENPP4,EPAS1,EPHX1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FBXO6,FEN1,G6PC1,GCH1,GIMAP7,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,LRRK2,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MTHFD2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NPR1,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,ORC1,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAD54B,RAD54L,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SBNO2,SIDT2,SLC11A1,SLC2A6,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TYMP,TYMS,UBE2T,UHRF1,UNG,VPS9D1,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0006139","Term":"nucleobase-containing compound metabolic process","Annotated":4751,"Significant":218,"Expected":286.94,"Rank in p.value_classic":4989,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ACOT4,ACSL1,ADARB2,ADORA3,AGT,AIM2,AK1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAF1B,CHTF18,CIITA,CLSPN,CMPK2,CTNS,CXCL10,CYLD,DAB2,DAZL,DGAT2,DLL1,DMC1,DPYS,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,ENPP4,EPAS1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FBXO6,FEN1,GCH1,GIMAP7,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,LBH,LITAF,LRP5,LRRK2,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NPR1,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,ORC1,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAD54B,RAD54L,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SBNO2,SIDT2,SLC11A1,SLC2A6,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TYMP,TYMS,UBE2T,UHRF1,UNG,VPS9D1,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0071704","Term":"organic substance metabolic process","Annotated":8635,"Significant":460,"Expected":521.52,"Rank in p.value_classic":4978,"p.value_elim":1,"p.value_classic":1,"genes":"AATK,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADORA3,AGR2,AGT,AIFM2,AIM2,AK1,ALAS1,AMER1,ANK2,ANKH,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CBR3,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,CMPK2,CNDP2,COLQ,COMP,CSF1,CTNS,CTRL,CTSL,CTSO,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DNPEP,DPYS,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM107A,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GIMAP7,GINS1,GINS2,GK,GLUL,GOLM1,GPR31,GRAMD4,GSAP,GSDMD,GSTK1,GTPBP1,HBEGF,HCAR2,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HSD11B1,HSD3B7,HTRA1,HYI,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL1RN,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LACTB,LAG3,LAMP3,LAP3,LBH,LCLAT1,LILRA2,LIMK2,LITAF,LMTK2,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MGAM2,MICAL2,MIR503,MMD,MMP25,MMP9,MSRB1,MTHFD2,MUC1,MVP,MYBL2,MYOZ2,NAAA,NCAPG2,NCF1,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRP1,NUB1,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OPTN,ORC1,OSBPL6,OSM,OTUD1,OVOL1,P2RX7,PADI2,PARP10,PARP12,PARP14,PARP3,PARP9,PCDH12,PCLAF,PCYT1A,PDCD1LG2,PDE3B,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PMAIP1,PML,PNPLA3,POLB,POLE2,PPM1E,PRKX,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCARF1,SCIMP,SEPTIN4,SERINC5,SERPING1,SGPL1,SIDT2,SLAMF1,SLAMF6,SLC11A1,SLC16A10,SLC2A5,SLC2A6,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAMBPL1,STAP1,STAT1,STAT2,STX1A,SUCNR1,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TTC39B,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XAF1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0043170","Term":"macromolecule metabolic process","Annotated":7463,"Significant":395,"Expected":450.73,"Rank in p.value_classic":4969,"p.value_elim":1,"p.value_classic":0.99998,"genes":"AATK,ABLIM3,ACOD1,ADAM8,ADAMTS15,ADARB2,ADGB,ADORA3,AGR2,AGT,AIM2,ALAS1,AMER1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDT1,CEACAM1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,CNDP2,COMP,CSF1,CTRL,CTSL,CTSO,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DHFR,DLL1,DMC1,DNPEP,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,EPAS1,EPHB3,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM107A,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GINS1,GINS2,GLUL,GRAMD4,GSAP,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HTRA1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LACTB,LAG3,LAMP3,LAP3,LBH,LILRA2,LIMK2,LITAF,LMTK2,LPL,LRP5,LRRK2,LTA,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP25,MMP9,MSRB1,MUC1,MVP,MYBL2,MYOZ2,NCAPG2,NCF1,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NR4A3,NRP1,NUB1,OAS2,OAS3,OLIG1,ONECUT2,OPTN,ORC1,OSM,OTUD1,OVOL1,P2RX7,PADI2,PARP10,PARP12,PARP14,PARP3,PARP9,PCDH12,PCLAF,PDCD1LG2,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLSCR1,PMAIP1,PML,POLB,POLE2,PPM1E,PRKX,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SEPTIN4,SERPING1,SIDT2,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAMBPL1,STAP1,STAT1,STAT2,STX1A,SUCNR1,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMTC1,TNFAIP6,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VEGFC,VRK2,WARS1,WEE1,WWP1,XAF1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0008152","Term":"metabolic process","Annotated":9054,"Significant":484,"Expected":546.82,"Rank in p.value_classic":4982,"p.value_elim":1,"p.value_classic":1,"genes":"AATK,ABCB1,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADORA3,AGR2,AGT,AIFM2,AIM2,AK1,ALAS1,AMER1,ANK2,ANKH,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ARMT1,ASB2,ASCL2,ATF3,ATF5,ATP13A2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C1R,C1RL,C1S,C2,C3,CA11,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CBR3,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,CMPK2,CNDP2,COLQ,COMP,CSF1,CTNS,CTRL,CTSL,CTSO,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DNPEP,DPYS,DRAM1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM107A,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,G0S2,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GIMAP7,GINS1,GINS2,GK,GLUL,GOLM1,GPR31,GRAMD4,GSAP,GSDMD,GSTK1,GTPBP1,HBEGF,HCAR2,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HSD11B1,HSD3B7,HTRA1,HYI,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL1RN,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LACTB,LAG3,LAMP3,LAP3,LBH,LCLAT1,LILRA2,LIMK2,LITAF,LMTK2,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MAP1LC3C,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MGAM2,MICAL2,MIR503,MMD,MMP25,MMP9,MSRB1,MTHFD2,MUC1,MVP,MYBL2,MYOZ2,NAAA,NCAPG2,NCF1,NCF1C,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRK,NRP1,NUB1,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OPTN,ORC1,OSBPL6,OSM,OTUD1,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP12,PARP14,PARP3,PARP9,PCDH12,PCLAF,PCYT1A,PDCD1LG2,PDE3B,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PMAIP1,PML,PNPLA3,POLB,POLE2,PPA1,PPM1E,PRKX,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTGER4,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCARF1,SCIMP,SCO2,SELENOP,SEPTIN4,SERINC5,SERPING1,SESN3,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC16A10,SLC20A1,SLC2A5,SLC2A6,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SQOR,SSBP3,STAMBPL1,STAP1,STAT1,STAT2,STEAP4,STX1A,SUCNR1,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMT1B,TMTC1,TNFAIP6,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF10,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TPCN1,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TTC39B,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XAF1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0006807","Term":"nitrogen compound metabolic process","Annotated":7805,"Significant":387,"Expected":471.39,"Rank in p.value_classic":5000,"p.value_elim":1,"p.value_classic":1,"genes":"AATK,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADORA3,AGT,AIM2,AK1,ALAS1,AMER1,AOC3,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,ASB2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLSPN,CMPK2,CNDP2,COLQ,COMP,CSF1,CTNS,CTRL,CTSL,CTSO,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DLL1,DMC1,DNPEP,DPYS,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM107A,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,G6PC1,GAL3ST4,GALNT18,GCH1,GCNT3,GGT5,GIMAP7,GINS1,GINS2,GLUL,GRAMD4,GSAP,GSTK1,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,HTRA1,IDO1,IDO2,IFI27,IFIH1,IL12A,IL15,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LACTB,LAMP3,LAP3,LBH,LILRA2,LIMK2,LITAF,LMTK2,LRP5,LRRK2,LYN,LYVE1,MAD2L1,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MEFV,MERTK,MICAL2,MIR503,MMD,MMP25,MMP9,MSRB1,MTHFD2,MUC1,MVP,MYBL2,MYOZ2,NAAA,NCAPG2,NCF1,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRP1,NUB1,OAS2,OAS3,OCA2,OLIG1,ONECUT2,ORC1,OSM,OTUD1,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP12,PARP14,PARP3,PARP9,PCLAF,PCYT1A,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLSCR1,PMAIP1,PML,POLB,POLE2,PPM1E,PRKX,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,S100A10,S1PR1,SAMD4A,SAT1,SBNO2,SEPTIN4,SERINC5,SERPING1,SGPL1,SIDT2,SLC11A1,SLC16A10,SLC2A6,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAMBPL1,STAT1,STAT2,STX1A,SUCNR1,TAL1,TANK,TAPBP,TBX21,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TK1,TLR7,TLR8,TMEM119,TMTC1,TNFAIP6,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VCAM1,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0044238","Term":"primary metabolic process","Annotated":8147,"Significant":405,"Expected":492.04,"Rank in p.value_classic":5001,"p.value_elim":1,"p.value_classic":1,"genes":"AATK,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADAMTS15,ADARB2,ADGB,ADORA3,AGT,AIM2,AK1,ALAS1,AMER1,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APOL2,APOL3,APOL4,APOL6,APPL2,ASB2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,C1R,C1RL,C1S,C2,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA3,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CENPF,CFB,CFH,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLSPN,CMPK2,CNDP2,COMP,CSF1,CTNS,CTRL,CTSL,CTSO,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DNPEP,DPYS,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM107A,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEM1C,FEN1,G6PC1,GAL3ST4,GALNT18,GCH1,GCNT3,GGT5,GHRL,GIMAP7,GINS1,GINS2,GK,GLUL,GOLM1,GPR31,GRAMD4,GSAP,GTPBP1,HBEGF,HCAR2,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,HSD11B1,HSD3B7,HTRA1,IDO1,IDO2,IFI27,IFIH1,IL12A,IL15,IL1RN,IL22RA2,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,LACTB,LAMP3,LAP3,LBH,LCLAT1,LILRA2,LIMK2,LITAF,LMTK2,LPL,LRP5,LRRK2,LTC4S,LYN,MAD2L1,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MEFV,MERTK,MGAM2,MICAL2,MIR503,MMD,MMP25,MMP9,MSRB1,MUC1,MVP,MYBL2,MYOZ2,NAAA,NCAPG2,NCF1,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRP1,NUB1,OAS2,OAS3,OCA2,OLIG1,ONECUT2,ORC1,OSBPL6,OSM,OTUD1,OVOL1,P2RX7,PADI2,PARP10,PARP12,PARP14,PARP3,PARP9,PCDH12,PCLAF,PCYT1A,PDE3B,PDE4B,PDK4,PGA3,PGA4,PGA5,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLCD3,PLCXD2,PLEK,PLPP4,PLSCR1,PMAIP1,PML,PNPLA3,POLB,POLE2,PPM1E,PRKX,PRTFDC1,PSMB10,PSMB8,PSMB9,PSME1,PSME2,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RHOBTB3,RIPK2,RMI2,RNF141,RNF19B,RNF213,RRM2,S100A10,S1PR1,SAMD4A,SBNO2,SCARF1,SEPTIN4,SERINC5,SERPING1,SGPL1,SIDT2,SLC11A1,SLC2A5,SLC2A6,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SSBP3,STAMBPL1,STAT1,STAT2,STX1A,SUCNR1,TAL1,TANK,TAPBP,TBX21,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TK1,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFSF10,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRABD2A,TRIM17,TRIM22,TRIM31,TRIM69,TSPAN15,TTC39B,TYMP,TYMS,TYRO3,UBD,UBE2L6,UBE2T,UHRF1,UNG,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:1901576","Term":"organic substance biosynthetic process","Annotated":6300,"Significant":300,"Expected":380.49,"Rank in p.value_classic":4997,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIM2,AK1,ALAS1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CDS1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CMPK2,COMP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DERL3,DGAT2,DHFR,DHRS9,DLL1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,EXO1,FAXDC2,FCN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GK,GLUL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,HSD3B7,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LCLAT1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OSBPL6,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PCYT1A,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLAAT3,PLEK,PLSCR1,PML,PNPLA3,POLB,POLE2,PRTFDC1,PTGER4,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RRM2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCIMP,SERINC5,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,UNG,VPS9D1,WARS1,WWP1,XAF1,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0046638","Term":"positive regulation of alpha-beta T cell differentiation","Annotated":46,"Significant":7,"Expected":2.78,"Rank in p.value_classic":871,"p.value_elim":1,"p.value_classic":0.01947,"genes":"CD80,CD83,HLA-DRA,HLA-DRB1,IL12RB1,RIPK2,SOCS1"} {"GO.ID":"GO:0045620","Term":"negative regulation of lymphocyte differentiation","Annotated":46,"Significant":11,"Expected":2.78,"Rank in p.value_classic":349,"p.value_elim":1,"p.value_classic":0.00007,"genes":"ASCL2,BCL6,CD74,CTLA4,FGL2,IRF1,JAK3,LAG3,SOCS1,TBX21,ZC3H12A"} {"GO.ID":"GO:0060416","Term":"response to growth hormone","Annotated":30,"Significant":5,"Expected":1.81,"Rank in p.value_classic":999,"p.value_elim":1,"p.value_classic":0.03215,"genes":"GHRL,JAK2,JAK3,LYN,PXN"} {"GO.ID":"GO:0042092","Term":"type 2 immune response","Annotated":37,"Significant":7,"Expected":2.23,"Rank in p.value_classic":681,"p.value_elim":1,"p.value_classic":0.00598,"genes":"ASCL2,BCL6,CD74,IDO1,NOD2,RSAD2,TBX21"} {"GO.ID":"GO:1903901","Term":"negative regulation of viral life cycle","Annotated":23,"Significant":6,"Expected":1.39,"Rank in p.value_classic":549,"p.value_elim":1,"p.value_classic":0.00198,"genes":"CIITA,FCN1,IFITM1,IFITM2,IFITM3,TRIM31"} {"GO.ID":"GO:0090266","Term":"regulation of mitotic cell cycle spindle assembly checkpoint","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":922,"p.value_elim":1,"p.value_classic":0.02473,"genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"GO.ID":"GO:0090232","Term":"positive regulation of spindle checkpoint","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":687,"p.value_elim":1,"p.value_classic":0.00608,"genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"GO.ID":"GO:0034340","Term":"response to type I interferon","Annotated":73,"Significant":13,"Expected":4.41,"Rank in p.value_classic":431,"p.value_elim":1,"p.value_classic":0.00038,"genes":"IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IRF7,NLRC5,OAS2,OAS3,STAT1,STAT2,TANK,ZBP1"} {"GO.ID":"GO:1901978","Term":"positive regulation of cell cycle checkpoint","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":923,"p.value_elim":1,"p.value_classic":0.02473,"genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"GO.ID":"GO:1905521","Term":"regulation of macrophage migration","Annotated":37,"Significant":8,"Expected":2.23,"Rank in p.value_classic":515,"p.value_elim":1,"p.value_classic":0.00138,"genes":"CCL5,CSF1,CX3CR1,MTUS1,P2RX4,SLAMF1,SLAMF8,STAP1"} {"GO.ID":"GO:0090715","Term":"immunological memory formation process","Annotated":12,"Significant":5,"Expected":0.72,"Rank in p.value_classic":445,"p.value_elim":1,"p.value_classic":0.00044,"genes":"BCL6,FGL2,HLA-DRA,HLA-DRB1,IL12RB1"} {"GO.ID":"GO:0070230","Term":"positive regulation of lymphocyte apoptotic process","Annotated":15,"Significant":7,"Expected":0.91,"Rank in p.value_classic":292,"p.value_elim":1,"p.value_classic":0.00001,"genes":"ADAM8,BCL2L11,CCL5,CD274,IDO1,P2RX7,PDCD1"} {"GO.ID":"GO:0043371","Term":"negative regulation of CD4-positive, alpha-beta T cell differentiation","Annotated":19,"Significant":5,"Expected":1.15,"Rank in p.value_classic":648,"p.value_elim":1,"p.value_classic":0.00453,"genes":"ASCL2,BCL6,JAK3,TBX21,ZC3H12A"} {"GO.ID":"GO:0043379","Term":"memory T cell differentiation","Annotated":11,"Significant":5,"Expected":0.66,"Rank in p.value_classic":406,"p.value_elim":1,"p.value_classic":0.00027,"genes":"BCL6,FGL2,HLA-DRA,HLA-DRB1,IL12RB1"} {"GO.ID":"GO:0044409","Term":"symbiont entry into host","Annotated":135,"Significant":24,"Expected":8.15,"Rank in p.value_classic":240,"p.value_elim":1,"p.value_classic":1.6e-06,"genes":"CD74,CD80,CDK1,CIITA,CTSL,CXADR,DYNLT1,FCN1,HAVCR1,HLA-DRB1,ICAM1,IFITM1,IFITM2,IFITM3,ITGB5,NRP1,PLSCR1,SLAMF1,TNFRSF14,TPCN1,TRIM22,TRIM31,TYRO3,WWP1"} {"GO.ID":"GO:0099500","Term":"vesicle fusion to plasma membrane","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":618,"p.value_elim":1,"p.value_classic":0.00351,"genes":"ERC2,PRRT2,STX11,STX1A,SYT1"} {"GO.ID":"GO:0032310","Term":"prostaglandin secretion","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":722,"p.value_elim":1,"p.value_classic":0.00812,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0032303","Term":"regulation of icosanoid secretion","Annotated":14,"Significant":4,"Expected":0.85,"Rank in p.value_classic":723,"p.value_elim":1,"p.value_classic":0.00812,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0032305","Term":"positive regulation of icosanoid secretion","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":688,"p.value_elim":1,"p.value_classic":0.00608,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0032306","Term":"regulation of prostaglandin secretion","Annotated":11,"Significant":4,"Expected":0.66,"Rank in p.value_classic":597,"p.value_elim":1,"p.value_classic":0.00309,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0032309","Term":"icosanoid secretion","Annotated":24,"Significant":4,"Expected":1.45,"Rank in p.value_classic":1142,"p.value_elim":1,"p.value_classic":0.0535,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0002396","Term":"MHC protein complex assembly","Annotated":18,"Significant":16,"Expected":1.09,"Rank in p.value_classic":29,"p.value_elim":1,"p.value_classic":3.7e-18,"genes":"B2M,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,TAPBP,TAPBPL"} {"GO.ID":"GO:0002399","Term":"MHC class II protein complex assembly","Annotated":13,"Significant":13,"Expected":0.79,"Rank in p.value_classic":38,"p.value_elim":1,"p.value_classic":1.3e-16,"genes":"B2M,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"GO.ID":"GO:0002363","Term":"alpha-beta T cell lineage commitment","Annotated":24,"Significant":5,"Expected":1.45,"Rank in p.value_classic":793,"p.value_elim":1,"p.value_classic":0.01291,"genes":"CTSL,IL12RB1,IRF4,SLAMF6,TBX21"} {"GO.ID":"GO:0141060","Term":"disruption of anatomical structure in another organism","Annotated":36,"Significant":7,"Expected":2.17,"Rank in p.value_classic":661,"p.value_elim":1,"p.value_classic":0.00511,"genes":"APOL1,CCL13,GBP1,GBP2,GBP3,GBP5,GBP7"} {"GO.ID":"GO:0141061","Term":"disruption of cell in another organism","Annotated":33,"Significant":7,"Expected":1.99,"Rank in p.value_classic":593,"p.value_elim":1,"p.value_classic":0.00306,"genes":"APOL1,CCL13,GBP1,GBP2,GBP3,GBP5,GBP7"} {"GO.ID":"GO:0044249","Term":"cellular biosynthetic process","Annotated":6244,"Significant":299,"Expected":377.11,"Rank in p.value_classic":4995,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIM2,AK1,ALAS1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CDS1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CMPK2,COMP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DERL3,DGAT2,DHFR,DHRS9,DLL1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,EXO1,FCN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GK,GLUL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,HSD3B7,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LCLAT1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PCYT1A,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLEK,PLSCR1,PML,PNPLA3,POLB,POLE2,PRTFDC1,PTGER4,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RRM2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCIMP,SERINC5,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,UNG,VPS9D1,WARS1,WWP1,XAF1,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0044237","Term":"cellular metabolic process","Annotated":8068,"Significant":413,"Expected":487.27,"Rank in p.value_classic":4993,"p.value_elim":1,"p.value_classic":1,"genes":"AATK,ABCB1,ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIFM2,AIM2,AK1,ALAS1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP6V0D2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,BUB1B,C1R,C1RL,C3,CA11,CALCOCO2,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CBR3,CCL5,CCNA2,CCNE2,CCNF,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDH5,CDK1,CDKL1,CDKN2C,CDS1,CDT1,CEACAM1,CENPF,CHAC1,CHAF1B,CHMP4C,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CLSPN,CMPK2,COMP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAPP1,DAZL,DEPTOR,DERL3,DGAT2,DHFR,DHRS3,DHRS9,DLL1,DMC1,DPYS,DRAM1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EEPD1,EGR2,EME1,ENPP2,ENPP4,EPAS1,EPHB3,EPHX1,EPOP,ERAP2,ESCO2,ETV7,EXO1,FAM111B,FAM20A,FANCE,FAS,FAXDC2,FBXO6,FCN1,FEN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GIMAP7,GINS1,GINS2,GK,GLUL,GSDMD,GSTK1,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HORMAD1,HSBP1L1,HSD3B7,HYI,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL22RA2,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KITLG,KLF4,KLRK1,LAG3,LAMP3,LBH,LCLAT1,LILRA2,LIMK2,LITAF,LMTK2,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MAF,MAFF,MAML3,MAP1LC3C,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MMD,MMP9,MTHFD2,MUC1,MVP,MYBL2,MYOZ2,NAAA,NCAPG2,NCF1,NCF1C,NECAB2,NEIL3,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPM2,NPR1,NR4A3,NRK,NRP1,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OPTN,ORC1,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCDH12,PCLAF,PCYT1A,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PKMYT1,PLA1A,PLAAT3,PLAAT4,PLB1,PLEK,PLPP4,PLSCR1,PMAIP1,PML,PNPLA3,POLB,POLE2,PPA1,PPM1E,PRKX,PRTFDC1,PTGER4,PTPRU,PYHIN1,RAD54B,RAD54L,RALB,RAPGEF2,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RNF213,RRM2,RSAD2,RUFY4,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCIMP,SCO2,SELENOP,SERINC5,SESN3,SGPL1,SH3PXD2A,SIDT2,SLAMF1,SLAMF6,SLAMF8,SLC11A1,SLC16A10,SLC20A1,SLC2A6,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SPTBN4,SQOR,SSBP3,STAP1,STAT1,STAT2,STEAP4,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TICRR,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFAIP8L3,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TPCN1,TRIM17,TRIM22,TRIM31,TSPAN15,TYMP,TYMS,TYRO3,UBE2T,UHRF1,UNG,VEGFC,VPS9D1,VRK2,WARS1,WEE1,WWP1,XAF1,XRCC2,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0002495","Term":"antigen processing and presentation of peptide antigen via MHC class II","Annotated":31,"Significant":16,"Expected":1.87,"Rank in p.value_classic":82,"p.value_elim":1,"p.value_classic":3.5e-12,"genes":"B2M,CD74,CTSL,CTSS,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"GO.ID":"GO:0140888","Term":"interferon-mediated signaling pathway","Annotated":85,"Significant":17,"Expected":5.13,"Rank in p.value_classic":287,"p.value_elim":1,"p.value_classic":1e-05,"genes":"IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IRF1,IRF7,JAK2,NLRC5,OAS2,OAS3,PARP14,PARP9,STAT1,STAT2,TANK,ZBP1"} {"GO.ID":"GO:0045066","Term":"regulatory T cell differentiation","Annotated":33,"Significant":11,"Expected":1.99,"Rank in p.value_classic":249,"p.value_elim":1,"p.value_classic":2.1e-06,"genes":"BCL6,BTN2A2,CD28,CTLA4,HLA-DRA,HLA-DRB1,HLA-G,IL4I1,IRF1,LAG3,SOCS1"} {"GO.ID":"GO:0070670","Term":"response to interleukin-4","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":774,"p.value_elim":1,"p.value_classic":0.01118,"genes":"CD300LF,JAK3,MCM2,PARP14,PML,RUFY4"} {"GO.ID":"GO:0140546","Term":"defense response to symbiont","Annotated":827,"Significant":141,"Expected":49.95,"Rank in p.value_classic":11,"p.value_elim":1,"genes":"ACOD1,ADAM8,AIM2,APOBEC3A,APOBEC3D,APOBEC3G,APOL1,APPL2,AURKB,C1QB,C1R,C1RL,C1S,C2,C3,C4A,C4B,CALCOCO2,CASP4,CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD274,CD300LF,CD74,CEACAM1,CFB,CFH,CIITA,CLEC10A,CLEC6A,COLEC12,CSF1,CTSS,CX3CR1,CXCL10,CXCL11,CXCL5,CXCL9,CYLD,DDX60,DTX3L,EDN1,FCN1,FGL2,GBP1,GBP2,GBP3,GBP4,GBP5,GBP6,GBP7,GCH1,GRAMD4,GSDMD,H2BC21,HLA-A,HLA-B,HLA-C,HLA-DPA1,HLA-E,HLA-F,HLA-G,IFI27,IFI35,IFI44L,IFIH1,IFIT2,IFIT3,IFIT5,IFITM1,IFITM2,IFITM3,IL12A,IL12RB1,IL15,IL27,IRF1,IRF4,IRF7,ISG20,JAK2,JAK3,KLRK1,LAG3,LILRA2,LYN,MCOLN2,MEFV,MSRB1,NCF1,NLRC5,NMI,NOD2,NUB1,OAS2,OAS3,OPTN,PARP14,PARP9,PLSCR1,PMAIP1,PML,PYHIN1,RAB20,RELB,RIPK2,RNF19B,RSAD2,RTP4,SCIMP,SERINC5,SERPING1,SLAMF1,SLAMF6,SLAMF7,SLAMF8,SLC11A1,STAT1,STAT2,TANK,TICAM2,TIFA,TLR10,TLR5,TLR7,TLR8,TNFRSF14,TRAFD1,TRIM22,TRIM31,TSPAN32,TYRO3,UBD,UBE2L6,ZBP1,ZC3H12A,ZNFX1"} {"GO.ID":"GO:0048499","Term":"synaptic vesicle membrane organization","Annotated":23,"Significant":5,"Expected":1.39,"Rank in p.value_classic":760,"p.value_elim":1,"p.value_classic":0.01074,"genes":"ERC2,PRRT2,STX11,STX1A,SYT1"} {"GO.ID":"GO:0042269","Term":"regulation of natural killer cell mediated cytotoxicity","Annotated":34,"Significant":10,"Expected":2.05,"Rank in p.value_classic":311,"p.value_elim":1,"p.value_classic":0.00002,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL12A,KLRK1,LAG3,SLAMF6"} {"GO.ID":"GO:0071357","Term":"cellular response to type I interferon","Annotated":67,"Significant":13,"Expected":4.05,"Rank in p.value_classic":383,"p.value_elim":1,"p.value_classic":0.00016,"genes":"IFI27,IFIH1,IFITM1,IFITM2,IFITM3,IRF7,NLRC5,OAS2,OAS3,STAT1,STAT2,TANK,ZBP1"} {"GO.ID":"GO:2000181","Term":"negative regulation of blood vessel morphogenesis","Annotated":84,"Significant":12,"Expected":5.07,"Rank in p.value_classic":644,"p.value_elim":1,"p.value_classic":0.00442,"genes":"AMOT,CXCL10,E2F2,GHRL,HLA-G,KLF4,MIR503,NPR1,PDE3B,PML,STAT1,THBS2"} {"GO.ID":"GO:0071378","Term":"cellular response to growth hormone stimulus","Annotated":21,"Significant":5,"Expected":1.27,"Rank in p.value_classic":706,"p.value_elim":1,"p.value_classic":0.00718,"genes":"GHRL,JAK2,JAK3,LYN,PXN"} {"GO.ID":"GO:1990823","Term":"response to leukemia inhibitory factor","Annotated":92,"Significant":12,"Expected":5.56,"Rank in p.value_classic":740,"p.value_elim":1,"p.value_classic":0.00917,"genes":"HELLS,ICAM1,INA,KLF4,MRAS,MYBL2,PADI2,PML,SBNO2,SNX10,SOX17,VEGFC"} {"GO.ID":"GO:0031294","Term":"lymphocyte costimulation","Annotated":41,"Significant":8,"Expected":2.48,"Rank in p.value_classic":585,"p.value_elim":1,"p.value_classic":0.00275,"genes":"CD274,CD28,CD80,KLRK1,LYN,PDCD1LG2,TNFRSF14,TNFSF13B"} {"GO.ID":"GO:0006396","Term":"RNA processing","Annotated":912,"Significant":6,"Expected":55.08,"Rank in p.value_classic":5006,"p.value_elim":1,"p.value_classic":1,"genes":"ADARB2,ISG20,KARS1,PIWIL4,TDRD9,TMTC1"} {"GO.ID":"GO:0002712","Term":"regulation of B cell mediated immunity","Annotated":51,"Significant":9,"Expected":3.08,"Rank in p.value_classic":605,"p.value_elim":1,"p.value_classic":0.00315,"genes":"BCL6,C3,CD28,CR1L,HLA-E,LTA,NOD2,PARP3,TBX21"} {"GO.ID":"GO:0002715","Term":"regulation of natural killer cell mediated immunity","Annotated":34,"Significant":10,"Expected":2.05,"Rank in p.value_classic":312,"p.value_elim":1,"p.value_classic":0.00002,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G,IL12A,KLRK1,LAG3,SLAMF6"} {"GO.ID":"GO:0002716","Term":"negative regulation of natural killer cell mediated immunity","Annotated":18,"Significant":6,"Expected":1.09,"Rank in p.value_classic":449,"p.value_elim":1,"p.value_classic":0.00047,"genes":"CEACAM1,HLA-A,HLA-B,HLA-E,HLA-F,HLA-G"} {"GO.ID":"GO:0034641","Term":"cellular nitrogen compound metabolic process","Annotated":5260,"Significant":231,"Expected":317.68,"Rank in p.value_classic":5002,"p.value_elim":1,"p.value_classic":1,"genes":"ABCG2,ABLIM3,ACOD1,ACOT4,ACSL1,ADARB2,ADORA3,AGT,AIM2,AK1,ALAS1,APOBEC3A,APOBEC3D,APOBEC3G,ASCL2,ATF3,ATF5,ATP8B1,AURKB,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,CAMK2D,CARD16,CASZ1,CCL5,CCNA2,CCNE2,CD274,CD28,CD38,CD40,CD74,CD80,CDC25A,CDC45,CDC6,CDCA5,CDCA7,CDK1,CDT1,CENPF,CHAC1,CHAF1B,CHTF18,CIITA,CLSPN,CMPK2,CTNS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DGAT2,DHFR,DLL1,DMC1,DPYS,DSCC1,DTL,DTX3L,E2F1,E2F2,E2F8,EBF4,EDA,EDN1,EEPD1,EGR2,EME1,ENPP4,EPAS1,EPOP,ESCO2,ETV7,EXO1,FAM111B,FANCE,FBXO6,FEN1,G6PC1,GCH1,GGT5,GIMAP7,GINS1,GINS2,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-DRB1,HORMAD1,HSBP1L1,IDO1,IDO2,IFI27,IL31RA,IL4I1,IRF1,IRF4,IRF7,ISG20,JADE2,JAK2,KARS1,KLF4,KLRK1,LBH,LITAF,LRP5,LRRK2,MAF,MAFF,MAML3,MCM10,MCM2,MCM4,MCM5,MCM6,MCM7,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NEIL3,NFXL1,NLRC5,NLRP12,NOD2,NPM2,NPR1,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,ORC1,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PRTFDC1,PYHIN1,RAD54B,RAD54L,RECQL4,RELB,RHEBL1,RIPK2,RMI2,RNF141,RRM2,S100A10,S1PR1,SAMD4A,SAT1,SBNO2,SIDT2,SLC11A1,SLC2A6,SLC4A7,SOX17,SP110,SP140,SSBP3,STAT1,STAT2,TAL1,TBX21,TDRD9,TESC,TFEC,TICAM2,TICRR,TK1,TLR7,TMTC1,TNFRSF11A,TNFSF18,TNFSF8,TONSL,TOP2A,TOX2,TRIM22,TRIM31,TYMP,TYMS,UBE2T,UHRF1,UNG,VPS9D1,WARS1,WEE1,WWP1,XRCC2,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704"} {"GO.ID":"GO:0032814","Term":"regulation of natural killer cell activation","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":775,"p.value_elim":1,"p.value_classic":0.01118,"genes":"HLA-E,IL12A,IL15,IL15RA,JAK2,TICAM2"} {"GO.ID":"GO:0048246","Term":"macrophage chemotaxis","Annotated":32,"Significant":6,"Expected":1.93,"Rank in p.value_classic":776,"p.value_elim":1,"p.value_classic":0.01118,"genes":"CCL5,CSF1,MTUS1,SLAMF1,SLAMF8,STAP1"} {"GO.ID":"GO:0051255","Term":"spindle midzone assembly","Annotated":13,"Significant":4,"Expected":0.79,"Rank in p.value_classic":689,"p.value_elim":1,"p.value_classic":0.00608,"genes":"AURKB,BIRC5,KIF23,PRC1"} {"GO.ID":"GO:1901343","Term":"negative regulation of vasculature development","Annotated":84,"Significant":12,"Expected":5.07,"Rank in p.value_classic":645,"p.value_elim":1,"p.value_classic":0.00442,"genes":"AMOT,CXCL10,E2F2,GHRL,HLA-G,KLF4,MIR503,NPR1,PDE3B,PML,STAT1,THBS2"} {"GO.ID":"GO:0002825","Term":"regulation of T-helper 1 type immune response","Annotated":28,"Significant":9,"Expected":1.69,"Rank in p.value_classic":316,"p.value_elim":1,"p.value_classic":0.00002,"genes":"ASCL2,CD80,IL12RB1,IL27,JAK3,RIPK2,SLAMF1,SLC11A1,TBX21"} {"GO.ID":"GO:0002834","Term":"regulation of response to tumor cell","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":619,"p.value_elim":1,"p.value_classic":0.00351,"genes":"CD274,CEACAM1,HLA-DRB1,IL12A,IL4I1"} {"GO.ID":"GO:0032651","Term":"regulation of interleukin-1 beta production","Annotated":82,"Significant":17,"Expected":4.95,"Rank in p.value_classic":272,"p.value_elim":1,"p.value_classic":6.3e-06,"genes":"AIM2,CARD16,CX3CR1,GBP5,GHRL,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,PML,RIPK2,TLR8,ZC3H12A"} {"GO.ID":"GO:0032623","Term":"interleukin-2 production","Annotated":55,"Significant":10,"Expected":3.32,"Rank in p.value_classic":525,"p.value_elim":1,"p.value_classic":0.00149,"genes":"CD28,CD80,CD83,GBP1,IRF4,LAG3,NOD2,PDE4B,RIPK2,TBX21"} {"GO.ID":"GO:0032611","Term":"interleukin-1 beta production","Annotated":82,"Significant":17,"Expected":4.95,"Rank in p.value_classic":273,"p.value_elim":1,"p.value_classic":6.3e-06,"genes":"AIM2,CARD16,CX3CR1,GBP5,GHRL,GSDMD,JAK2,LILRA2,LPL,MEFV,NLRP12,NOD2,P2RX7,PML,RIPK2,TLR8,ZC3H12A"} {"GO.ID":"GO:0032649","Term":"regulation of type II interferon production","Annotated":94,"Significant":24,"Expected":5.68,"Rank in p.value_classic":124,"p.value_elim":1,"p.value_classic":1e-09,"genes":"BTN3A1,BTN3A2,CD274,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,IL12A,IL12RB1,IL12RB2,IL27,JAK2,KLRK1,LTA,NOD2,PDCD1LG2,PDE4B,RIPK2,SLAMF1,SLAMF6,SLC11A1,TLR7,TLR8,ZC3H12A"} {"GO.ID":"GO:0032635","Term":"interleukin-6 production","Annotated":132,"Significant":17,"Expected":7.97,"Rank in p.value_classic":564,"p.value_elim":1,"p.value_classic":0.00247,"genes":"BANK1,CD74,GHRL,HGF,HLA-B,IFIH1,LILRA2,LPL,NLRP12,NOD2,P2RX7,RIPK2,SCIMP,SLAMF1,TLR7,TLR8,ZC3H12A"} {"GO.ID":"GO:0009058","Term":"biosynthetic process","Annotated":6343,"Significant":301,"Expected":383.09,"Rank in p.value_classic":4998,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ACOT4,ACSL1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIM2,AK1,ALAS1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CDS1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CISH,CLEC6A,CLEC9A,CMPK2,COMP,CSF1,CTNS,CTSL,CTSS,CX3CR1,CXCL10,CYLD,CYP1A1,DAB2,DAZL,DERL3,DGAT2,DHFR,DHRS9,DLL1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,EXO1,FAXDC2,FCN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GGT5,GHRL,GK,GLUL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,HSD3B7,IDO1,IDO2,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LCLAT1,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LTC4S,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NPR1,NR4A3,OAS2,OAS3,OCA2,OLIG1,ONECUT2,OSBPL6,OSM,OVOL1,P2RX4,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PCYT1A,PDCD1LG2,PDE4B,PDK4,PID1,PIM1,PIWIL4,PKIB,PLAAT3,PLEK,PLSCR1,PML,PNPLA3,POLB,POLE2,PRTFDC1,PTGER4,PYHIN1,RAPGEF2,RELB,RHEBL1,RIPK2,RNF141,RRM2,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SAT1,SBNO2,SCIMP,SERINC5,SLAMF1,SLAMF6,SLC11A1,SLC45A3,SLC4A7,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMEM150A,TMTC1,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,UNG,VPS9D1,WARS1,WWP1,XAF1,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0009059","Term":"macromolecule biosynthetic process","Annotated":5536,"Significant":266,"Expected":334.35,"Rank in p.value_classic":4986,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIM2,ALAS1,ANK2,ANKH,APOBEC3A,APOBEC3D,APOBEC3G,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CHTF18,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DERL3,DHFR,DLL1,DSCC1,DSE,DTL,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,EXO1,FCN1,G6PC1,GAL3ST4,GALNT18,GBP1,GBP5,GBP7,GCH1,GCNT3,GHRL,GLUL,GSDMD,GTPBP1,HBEGF,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NECAB2,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PCLAF,PDCD1LG2,PDE4B,PID1,PIM1,PIWIL4,PKIB,PLSCR1,PML,POLB,POLE2,PTGER4,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOAT1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TIFAB,TK1,TLR5,TLR7,TLR8,TMEM119,TMTC1,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,UNG,WARS1,WWP1,XAF1,XRN1,XYLT1,ZC3H12A,ZDHHC19,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0002504","Term":"antigen processing and presentation of peptide or polysaccharide antigen via MHC class II","Annotated":33,"Significant":16,"Expected":1.99,"Rank in p.value_classic":89,"p.value_elim":1,"p.value_classic":1.2e-11,"genes":"B2M,CD74,CTSL,CTSS,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"GO.ID":"GO:0032609","Term":"type II interferon production","Annotated":94,"Significant":24,"Expected":5.68,"Rank in p.value_classic":125,"p.value_elim":1,"p.value_classic":1e-09,"genes":"BTN3A1,BTN3A2,CD274,HLA-A,HLA-DPA1,HLA-DPB1,HLA-DRB1,IL12A,IL12RB1,IL12RB2,IL27,JAK2,KLRK1,LTA,NOD2,PDCD1LG2,PDE4B,RIPK2,SLAMF1,SLAMF6,SLC11A1,TLR7,TLR8,ZC3H12A"} {"GO.ID":"GO:0001562","Term":"response to protozoan","Annotated":24,"Significant":9,"Expected":1.45,"Rank in p.value_classic":271,"p.value_elim":1,"p.value_classic":5.9e-06,"genes":"BATF2,GBP1,GBP2,GBP4,GBP6,GBP7,IRF4,SLC11A1,TSPAN32"} {"GO.ID":"GO:0072567","Term":"chemokine (C-X-C motif) ligand 2 production","Annotated":18,"Significant":5,"Expected":1.09,"Rank in p.value_classic":620,"p.value_elim":1,"p.value_classic":0.00351,"genes":"CD74,KLF4,LPL,MCOLN2,OAS3"} {"GO.ID":"GO:0072538","Term":"T-helper 17 type immune response","Annotated":41,"Significant":8,"Expected":2.48,"Rank in p.value_classic":586,"p.value_elim":1,"p.value_classic":0.00275,"genes":"ASCL2,CLEC6A,IL12RB1,IRF4,JAK2,SLAMF6,TBX21,ZC3H12A"} {"GO.ID":"GO:0000022","Term":"mitotic spindle elongation","Annotated":11,"Significant":4,"Expected":0.66,"Rank in p.value_classic":598,"p.value_elim":1,"p.value_classic":0.00309,"genes":"AURKB,BIRC5,KIF23,PRC1"} {"GO.ID":"GO:0015732","Term":"prostaglandin transport","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":924,"p.value_elim":1,"p.value_classic":0.02473,"genes":"EDN1,P2RX4,P2RX7,TNFRSF11A"} {"GO.ID":"GO:0046850","Term":"regulation of bone remodeling","Annotated":42,"Significant":7,"Expected":2.54,"Rank in p.value_classic":786,"p.value_elim":1,"p.value_classic":0.01208,"genes":"ADAM8,CD38,P2RX7,PDK4,S1PR1,TMEM119,TNFRSF11A"} {"GO.ID":"GO:1903504","Term":"regulation of mitotic spindle checkpoint","Annotated":19,"Significant":4,"Expected":1.15,"Rank in p.value_classic":925,"p.value_elim":1,"p.value_classic":0.02473,"genes":"AURKB,BIRC5,MAD2L1,NDC80"} {"GO.ID":"GO:0007588","Term":"excretion","Annotated":18,"Significant":4,"Expected":1.09,"Rank in p.value_classic":883,"p.value_elim":1,"p.value_classic":0.02048,"genes":"ABCG2,AGT,EDN1,NPR1"} {"GO.ID":"GO:0006873","Term":"intracellular monoatomic ion homeostasis","Annotated":409,"Significant":37,"Expected":24.7,"Rank in p.value_classic":737,"p.value_elim":1,"p.value_classic":0.00902,"genes":"ANK2,ATP13A2,ATP1B2,ATP6V0D2,B2M,CAMK2D,CCL13,CCL15,CCL5,CCL7,CCL8,CD40,CDH5,CXCL10,CXCL11,CXCL9,EDN1,ERC2,F2RL3,KCNJ2,LRRK2,LYN,MT2A,OCA2,P2RX7,PML,RAB20,SCO2,SLAMF8,SLC11A1,SLC31A2,SLC4A7,SRI,STEAP4,SV2B,TGM2,TRDN"} {"GO.ID":"GO:0032944","Term":"regulation of mononuclear cell proliferation","Annotated":196,"Significant":39,"Expected":11.84,"Rank in p.value_classic":94,"p.value_elim":1,"p.value_classic":2.8e-11,"genes":"BCL6,BTN2A2,CCL5,CD274,CD28,CD38,CD74,CD80,CSF1,CTLA4,GPR183,HLA-A,HLA-DMB,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-G,IDO1,IL12A,IL12RB1,IL15,IL27,IL4I1,IL7,IRF1,JAK2,KITLG,LYN,PDCD1LG2,RIPK2,SLAMF1,TNFRSF14,TNFRSF21,TNFSF13B,TNFSF18,TNFSF8,TSPAN32,VCAM1"} {"GO.ID":"GO:0071621","Term":"granulocyte chemotaxis","Annotated":102,"Significant":19,"Expected":6.16,"Rank in p.value_classic":284,"p.value_elim":1,"p.value_classic":9.6e-06,"genes":"CCL13,CCL15,CCL18,CCL5,CCL7,CCL8,CD300H,CD74,CSF1,CXADR,CXCL10,CXCL11,CXCL5,CXCL9,EDN1,NOD2,PDE4B,SLAMF1,TNFAIP6"} {"GO.ID":"GO:0010467","Term":"gene expression","Annotated":5107,"Significant":243,"Expected":308.44,"Rank in p.value_classic":4984,"p.value_elim":1,"p.value_classic":1,"genes":"ABLIM3,ACOD1,ADAM8,ADARB2,ADORA3,AGR2,AGT,AIM2,ANK2,ANKH,APPL2,ASCL2,ATF3,ATF5,ATP13A2,ATP8B1,AURKB,B2M,BACH1,BANK1,BATF2,BATF3,BAZ1A,BCL6,BHLHE41,BIRC5,BMAL2,BRCA1,BTN2A2,BTN3A1,BTN3A2,BTN3A3,C1R,C1RL,C3,CAMK2D,CARD16,CASP4,CASP7,CASZ1,CCL5,CCNA2,CD274,CD28,CD38,CD40,CD74,CD80,CD83,CDCA7,CDH5,CDK1,CEACAM1,CENPF,CHAC1,CIITA,CLEC6A,CLEC9A,COMP,CSF1,CTSL,CTSS,CX3CR1,CXCL10,CYLD,DAB2,DAZL,DHFR,DLL1,DTNBP1,DTX3L,E2F1,E2F2,E2F8,EBF4,ECEL1,EDA,EDN1,EGR2,EPAS1,EPOP,ETV7,EXO1,FCN1,G6PC1,GBP1,GBP5,GBP7,GHRL,GSDMD,GTPBP1,HELLS,HESX1,HGF,HIVEP2,HLA-A,HLA-B,HLA-DPA1,HLA-DPB1,HLA-DRB1,HLA-E,HLA-F,HLA-G,HSBP1L1,IDO1,IFI27,IFIH1,IL12A,IL12RB1,IL12RB2,IL15,IL27,IL31RA,IL4I1,IL7,IQGAP3,IRF1,IRF4,IRF7,ISG20,ITK,JADE2,JAK2,JAK3,KARS1,KLF4,KLRK1,LAG3,LAMP3,LBH,LILRA2,LITAF,LPL,LRP5,LRRK2,LTA,LYN,MAF,MAFF,MAML3,MCOLN2,MEFV,MERTK,MICAL2,MIR503,MUC1,MYBL2,MYOZ2,NCAPG2,NCF1,NFXL1,NLRC5,NLRP12,NMI,NOD2,NR4A3,OAS2,OAS3,OLIG1,ONECUT2,OSM,OVOL1,P2RX7,PADI2,PARP10,PARP14,PARP3,PARP9,PDCD1LG2,PDE4B,PID1,PIM1,PIWIL4,PLSCR1,PML,POLB,PTGER4,PYHIN1,RELB,RHEBL1,RIPK2,RNF141,RSAD2,S100A10,S100A13,S1PR1,SAMD4A,SBNO2,SCIMP,SLAMF1,SLAMF6,SLC11A1,SOCS1,SOX17,SP110,SP140,SSBP3,STAP1,STAT1,STAT2,TAL1,TANK,TAPBP,TBX21,TCF19,TDRD9,TESC,TFEC,TGM2,THBD,TICAM2,TIFAB,TLR5,TLR7,TLR8,TMEM119,TMTC1,TNFRSF11A,TNFRSF14,TNFRSF21,TNFSF18,TNFSF8,TOP2A,TOX2,TRIM17,TRIM22,TRIM31,TSPAN15,TYMS,UHRF1,UNG,WARS1,WWP1,XAF1,XRN1,ZC3H12A,ZMYND15,ZNF367,ZNF395,ZNF608,ZNF695,ZNF704,ZNFX1"} {"GO.ID":"GO:0009451","Term":"RNA modification","Annotated":171,"Significant":4,"Expected":10.33,"Rank in p.value_classic":4875,"p.value_elim":1,"p.value_classic":0.99341,"genes":"ADARB2,APOBEC3A,APOBEC3D,APOBEC3G"} {"GO.ID":"GO:0000012","Term":"single strand break repair","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5007,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000027","Term":"ribosomal large subunit assembly","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5008,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000028","Term":"ribosomal small subunit assembly","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5009,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000054","Term":"ribosomal subunit export from nucleus","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5010,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000096","Term":"sulfur amino acid metabolic process","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5011,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000097","Term":"sulfur amino acid biosynthetic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5012,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000154","Term":"rRNA modification","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":5013,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000244","Term":"spliceosomal tri-snRNP complex assembly","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5014,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000245","Term":"spliceosomal complex assembly","Annotated":75,"Significant":0,"Expected":4.53,"Rank in p.value_classic":5015,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000271","Term":"polysaccharide biosynthetic process","Annotated":54,"Significant":0,"Expected":3.26,"Rank in p.value_classic":5016,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000290","Term":"deadenylation-dependent decapping of nuclear-transcribed mRNA","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5017,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000291","Term":"nuclear-transcribed mRNA catabolic process, exonucleolytic","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5018,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000338","Term":"protein deneddylation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5019,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000375","Term":"RNA splicing, via transesterification reactions","Annotated":287,"Significant":0,"Expected":17.33,"Rank in p.value_classic":5020,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000377","Term":"RNA splicing, via transesterification reactions with bulged adenosine as nucleophile","Annotated":283,"Significant":0,"Expected":17.09,"Rank in p.value_classic":5021,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000380","Term":"alternative mRNA splicing, via spliceosome","Annotated":65,"Significant":0,"Expected":3.93,"Rank in p.value_classic":5022,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000381","Term":"regulation of alternative mRNA splicing, via spliceosome","Annotated":47,"Significant":0,"Expected":2.84,"Rank in p.value_classic":5023,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000387","Term":"spliceosomal snRNP assembly","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5024,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000394","Term":"RNA splicing, via endonucleolytic cleavage and ligation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5025,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000398","Term":"mRNA splicing, via spliceosome","Annotated":283,"Significant":0,"Expected":17.09,"Rank in p.value_classic":5026,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000413","Term":"protein peptidyl-prolyl isomerization","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5027,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000447","Term":"endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5028,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000460","Term":"maturation of 5.8S rRNA","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5029,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000462","Term":"maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5030,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000463","Term":"maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5031,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000466","Term":"maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5032,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000470","Term":"maturation of LSU-rRNA","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5033,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000479","Term":"endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5034,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000491","Term":"small nucleolar ribonucleoprotein complex assembly","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5035,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000492","Term":"box C/D snoRNP assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5036,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000722","Term":"telomere maintenance via recombination","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5037,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000729","Term":"DNA double-strand break processing","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5038,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000959","Term":"mitochondrial RNA metabolic process","Annotated":53,"Significant":0,"Expected":3.2,"Rank in p.value_classic":5039,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000963","Term":"mitochondrial RNA processing","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5040,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0000966","Term":"RNA 5'-end processing","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5041,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001408","Term":"guanine nucleotide transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5042,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001502","Term":"cartilage condensation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5043,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001510","Term":"RNA methylation","Annotated":87,"Significant":0,"Expected":5.25,"Rank in p.value_classic":5044,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001522","Term":"pseudouridine synthesis","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5045,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001573","Term":"ganglioside metabolic process","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5046,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001574","Term":"ganglioside biosynthetic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5047,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001675","Term":"acrosome assembly","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5048,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001682","Term":"tRNA 5'-leader removal","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5049,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001732","Term":"formation of cytoplasmic translation initiation complex","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5050,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001754","Term":"eye photoreceptor cell differentiation","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5051,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001759","Term":"organ induction","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5052,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001767","Term":"establishment of lymphocyte polarity","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5053,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001768","Term":"establishment of T cell polarity","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5054,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001771","Term":"immunological synapse formation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5055,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001829","Term":"trophectodermal cell differentiation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5056,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0001921","Term":"positive regulation of receptor recycling","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5057,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002082","Term":"regulation of oxidative phosphorylation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5058,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002089","Term":"lens morphogenesis in camera-type eye","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5059,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002093","Term":"auditory receptor cell morphogenesis","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5060,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002097","Term":"tRNA wobble base modification","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5061,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002098","Term":"tRNA wobble uridine modification","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5062,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002115","Term":"store-operated calcium entry","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5063,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002181","Term":"cytoplasmic translation","Annotated":157,"Significant":0,"Expected":9.48,"Rank in p.value_classic":5064,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002183","Term":"cytoplasmic translational initiation","Annotated":43,"Significant":0,"Expected":2.6,"Rank in p.value_classic":5065,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002320","Term":"lymphoid progenitor cell differentiation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5066,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002328","Term":"pro-B cell differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5067,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002446","Term":"neutrophil mediated immunity","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5068,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0002934","Term":"desmosome organization","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5069,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003085","Term":"negative regulation of systemic arterial blood pressure","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5070,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003128","Term":"heart field specification","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5071,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003156","Term":"regulation of animal organ formation","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5072,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003161","Term":"cardiac conduction system development","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5073,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003170","Term":"heart valve development","Annotated":66,"Significant":0,"Expected":3.99,"Rank in p.value_classic":5074,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003171","Term":"atrioventricular valve development","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5075,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003174","Term":"mitral valve development","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5076,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003176","Term":"aortic valve development","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5077,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003177","Term":"pulmonary valve development","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5078,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003179","Term":"heart valve morphogenesis","Annotated":55,"Significant":0,"Expected":3.32,"Rank in p.value_classic":5079,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003180","Term":"aortic valve morphogenesis","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":5080,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003181","Term":"atrioventricular valve morphogenesis","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5081,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003183","Term":"mitral valve morphogenesis","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5082,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003184","Term":"pulmonary valve morphogenesis","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5083,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003188","Term":"heart valve formation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5084,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003197","Term":"endocardial cushion development","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5085,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003198","Term":"epithelial to mesenchymal transition involved in endocardial cushion formation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5086,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003203","Term":"endocardial cushion morphogenesis","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5087,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003207","Term":"cardiac chamber formation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5088,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003208","Term":"cardiac ventricle morphogenesis","Annotated":55,"Significant":0,"Expected":3.32,"Rank in p.value_classic":5089,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003209","Term":"cardiac atrium morphogenesis","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5090,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003214","Term":"cardiac left ventricle morphogenesis","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5091,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003215","Term":"cardiac right ventricle morphogenesis","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5092,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003222","Term":"ventricular trabecula myocardium morphogenesis","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5093,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003228","Term":"atrial cardiac muscle tissue development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5094,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003229","Term":"ventricular cardiac muscle tissue development","Annotated":46,"Significant":0,"Expected":2.78,"Rank in p.value_classic":5095,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003231","Term":"cardiac ventricle development","Annotated":104,"Significant":0,"Expected":6.28,"Rank in p.value_classic":5096,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003272","Term":"endocardial cushion formation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5097,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003281","Term":"ventricular septum development","Annotated":64,"Significant":0,"Expected":3.87,"Rank in p.value_classic":5098,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003299","Term":"muscle hypertrophy in response to stress","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5099,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003382","Term":"epithelial cell morphogenesis","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5100,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003401","Term":"axis elongation","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5101,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003407","Term":"neural retina development","Annotated":53,"Significant":0,"Expected":3.2,"Rank in p.value_classic":5102,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0003413","Term":"chondrocyte differentiation involved in endochondral bone morphogenesis","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5103,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0005978","Term":"glycogen biosynthetic process","Annotated":37,"Significant":0,"Expected":2.23,"Rank in p.value_classic":5104,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0005979","Term":"regulation of glycogen biosynthetic process","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5105,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006000","Term":"fructose metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5106,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006002","Term":"fructose 6-phosphate metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5107,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006004","Term":"fucose metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5108,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006040","Term":"amino sugar metabolic process","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5109,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006044","Term":"N-acetylglucosamine metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5110,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006047","Term":"UDP-N-acetylglucosamine metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5111,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006054","Term":"N-acetylneuraminate metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5112,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006067","Term":"ethanol metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5113,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006089","Term":"lactate metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5114,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006098","Term":"pentose-phosphate shunt","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5115,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006099","Term":"tricarboxylic acid cycle","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5116,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006103","Term":"2-oxoglutarate metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5117,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006111","Term":"regulation of gluconeogenesis","Annotated":41,"Significant":0,"Expected":2.48,"Rank in p.value_classic":5118,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006120","Term":"mitochondrial electron transport, NADH to ubiquinone","Annotated":49,"Significant":0,"Expected":2.96,"Rank in p.value_classic":5119,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006122","Term":"mitochondrial electron transport, ubiquinol to cytochrome c","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5120,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006123","Term":"mitochondrial electron transport, cytochrome c to oxygen","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5121,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006144","Term":"purine nucleobase metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5122,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006167","Term":"AMP biosynthetic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5123,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006177","Term":"GMP biosynthetic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5124,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006188","Term":"IMP biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5125,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006241","Term":"CTP biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5126,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006264","Term":"mitochondrial DNA replication","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5127,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006289","Term":"nucleotide-excision repair","Annotated":78,"Significant":0,"Expected":4.71,"Rank in p.value_classic":5128,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006309","Term":"apoptotic DNA fragmentation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5129,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006337","Term":"nucleosome disassembly","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5130,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006353","Term":"DNA-templated transcription termination","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5131,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006356","Term":"regulation of transcription by RNA polymerase I","Annotated":46,"Significant":0,"Expected":2.78,"Rank in p.value_classic":5132,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006359","Term":"regulation of transcription by RNA polymerase III","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5133,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006360","Term":"transcription by RNA polymerase I","Annotated":70,"Significant":0,"Expected":4.23,"Rank in p.value_classic":5134,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006361","Term":"transcription initiation at RNA polymerase I promoter","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5135,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006369","Term":"termination of RNA polymerase II transcription","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5136,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006376","Term":"mRNA splice site recognition","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5137,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006378","Term":"mRNA polyadenylation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5138,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006383","Term":"transcription by RNA polymerase III","Annotated":60,"Significant":0,"Expected":3.62,"Rank in p.value_classic":5139,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006388","Term":"tRNA splicing, via endonucleolytic cleavage and ligation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5140,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006390","Term":"mitochondrial transcription","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5141,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006400","Term":"tRNA modification","Annotated":91,"Significant":0,"Expected":5.5,"Rank in p.value_classic":5142,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006405","Term":"RNA export from nucleus","Annotated":86,"Significant":0,"Expected":5.19,"Rank in p.value_classic":5143,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006406","Term":"mRNA export from nucleus","Annotated":68,"Significant":0,"Expected":4.11,"Rank in p.value_classic":5144,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006415","Term":"translational termination","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5145,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006448","Term":"regulation of translational elongation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5146,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006450","Term":"regulation of translational fidelity","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5147,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006465","Term":"signal peptide processing","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5148,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006474","Term":"N-terminal protein amino acid acetylation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5149,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006476","Term":"protein deacetylation","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5150,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006479","Term":"protein methylation","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5151,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006488","Term":"dolichol-linked oligosaccharide biosynthetic process","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5152,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006490","Term":"oligosaccharide-lipid intermediate biosynthetic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5153,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006491","Term":"N-glycan processing","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5154,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006505","Term":"GPI anchor metabolic process","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5155,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006506","Term":"GPI anchor biosynthetic process","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5156,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006515","Term":"protein quality control for misfolded or incompletely synthesized proteins","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5157,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006517","Term":"protein deglycosylation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5158,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006525","Term":"arginine metabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5159,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006534","Term":"cysteine metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5160,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006555","Term":"methionine metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5161,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006577","Term":"amino-acid betaine metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5162,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006613","Term":"cotranslational protein targeting to membrane","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5163,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006614","Term":"SRP-dependent cotranslational protein targeting to membrane","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5164,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006620","Term":"post-translational protein targeting to endoplasmic reticulum membrane","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5165,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006622","Term":"protein targeting to lysosome","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5166,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006623","Term":"protein targeting to vacuole","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5167,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006635","Term":"fatty acid beta-oxidation","Annotated":68,"Significant":0,"Expected":4.11,"Rank in p.value_classic":5168,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006646","Term":"phosphatidylethanolamine biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5169,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006655","Term":"phosphatidylglycerol biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5170,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006677","Term":"glycosylceramide metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5171,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006684","Term":"sphingomyelin metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5172,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006686","Term":"sphingomyelin biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5173,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006687","Term":"glycosphingolipid metabolic process","Annotated":50,"Significant":0,"Expected":3.02,"Rank in p.value_classic":5174,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006688","Term":"glycosphingolipid biosynthetic process","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5175,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006695","Term":"cholesterol biosynthetic process","Annotated":46,"Significant":0,"Expected":2.78,"Rank in p.value_classic":5176,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006734","Term":"NADH metabolic process","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5177,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006735","Term":"NADH regeneration","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5178,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006739","Term":"NADP metabolic process","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5179,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006740","Term":"NADPH regeneration","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5180,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006744","Term":"ubiquinone biosynthetic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5181,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006829","Term":"zinc ion transport","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5182,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006851","Term":"mitochondrial calcium ion transmembrane transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5183,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006857","Term":"oligopeptide transport","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5184,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006863","Term":"purine nucleobase transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5185,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006891","Term":"intra-Golgi vesicle-mediated transport","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5186,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006896","Term":"Golgi to vacuole transport","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5187,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006901","Term":"vesicle coating","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5188,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006903","Term":"vesicle targeting","Annotated":64,"Significant":0,"Expected":3.87,"Rank in p.value_classic":5189,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006971","Term":"hypotonic response","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5190,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006972","Term":"hyperosmotic response","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5191,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006983","Term":"ER overload response","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5192,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0006999","Term":"nuclear pore organization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5193,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007000","Term":"nucleolus organization","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5194,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007008","Term":"outer mitochondrial membrane organization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5195,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007020","Term":"microtubule nucleation","Annotated":45,"Significant":0,"Expected":2.72,"Rank in p.value_classic":5196,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007026","Term":"negative regulation of microtubule depolymerization","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5197,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007028","Term":"cytoplasm organization","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5198,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007042","Term":"lysosomal lumen acidification","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5199,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007084","Term":"mitotic nuclear membrane reassembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5200,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007097","Term":"nuclear migration","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5201,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007158","Term":"neuron cell-cell adhesion","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5202,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007175","Term":"negative regulation of epidermal growth factor-activated receptor activity","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5203,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007194","Term":"negative regulation of adenylate cyclase activity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5204,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007213","Term":"G protein-coupled acetylcholine receptor signaling pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5205,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007250","Term":"activation of NF-kappaB-inducing kinase activity","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5206,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007288","Term":"sperm axoneme assembly","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5207,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007289","Term":"spermatid nucleus differentiation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5208,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007339","Term":"binding of sperm to zona pellucida","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5209,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007398","Term":"ectoderm development","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5210,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007494","Term":"midgut development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5211,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007530","Term":"sex determination","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5212,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007617","Term":"mating behavior","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5213,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0007635","Term":"chemosensory behavior","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5214,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008090","Term":"retrograde axonal transport","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5215,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008211","Term":"glucocorticoid metabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5216,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008213","Term":"protein alkylation","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5217,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008272","Term":"sulfate transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5218,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008298","Term":"intracellular mRNA localization","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5219,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008356","Term":"asymmetric cell division","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5220,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008380","Term":"RNA splicing","Annotated":423,"Significant":0,"Expected":25.55,"Rank in p.value_classic":5221,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0008611","Term":"ether lipid biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5222,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009062","Term":"fatty acid catabolic process","Annotated":89,"Significant":0,"Expected":5.38,"Rank in p.value_classic":5223,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009066","Term":"aspartate family amino acid metabolic process","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5224,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009067","Term":"aspartate family amino acid biosynthetic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5225,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009068","Term":"aspartate family amino acid catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5226,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009071","Term":"serine family amino acid catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5227,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009081","Term":"branched-chain amino acid metabolic process","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5228,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009083","Term":"branched-chain amino acid catabolic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5229,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009086","Term":"methionine biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5230,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009110","Term":"vitamin biosynthetic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5231,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009127","Term":"purine nucleoside monophosphate biosynthetic process","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5232,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009143","Term":"nucleoside triphosphate catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5233,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009151","Term":"purine deoxyribonucleotide metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5234,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009156","Term":"ribonucleoside monophosphate biosynthetic process","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5235,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009168","Term":"purine ribonucleoside monophosphate biosynthetic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5236,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009174","Term":"pyrimidine ribonucleoside monophosphate biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5237,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009208","Term":"pyrimidine ribonucleoside triphosphate metabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5238,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009209","Term":"pyrimidine ribonucleoside triphosphate biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5239,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009220","Term":"pyrimidine ribonucleotide biosynthetic process","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5240,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009225","Term":"nucleotide-sugar metabolic process","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5241,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009226","Term":"nucleotide-sugar biosynthetic process","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5242,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009250","Term":"glucan biosynthetic process","Annotated":37,"Significant":0,"Expected":2.23,"Rank in p.value_classic":5243,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009301","Term":"snRNA transcription","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5244,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009303","Term":"rRNA transcription","Annotated":40,"Significant":0,"Expected":2.42,"Rank in p.value_classic":5245,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009304","Term":"tRNA transcription","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5246,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009312","Term":"oligosaccharide biosynthetic process","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5247,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009313","Term":"oligosaccharide catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5248,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009437","Term":"carnitine metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5249,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009584","Term":"detection of visible light","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5250,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009642","Term":"response to light intensity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5251,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009651","Term":"response to salt stress","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5252,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009950","Term":"dorsal/ventral axis specification","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5253,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0009988","Term":"cell-cell recognition","Annotated":40,"Significant":0,"Expected":2.42,"Rank in p.value_classic":5254,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010002","Term":"cardioblast differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5255,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010092","Term":"specification of animal organ identity","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5256,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010225","Term":"response to UV-C","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5257,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010226","Term":"response to lithium ion","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5258,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010257","Term":"NADH dehydrogenase complex assembly","Annotated":60,"Significant":0,"Expected":3.62,"Rank in p.value_classic":5259,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010457","Term":"centriole-centriole cohesion","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5260,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010470","Term":"regulation of gastrulation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5261,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010640","Term":"regulation of platelet-derived growth factor receptor signaling pathway","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5262,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010642","Term":"negative regulation of platelet-derived growth factor receptor signaling pathway","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5263,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010714","Term":"positive regulation of collagen metabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5264,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010719","Term":"negative regulation of epithelial to mesenchymal transition","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5265,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010745","Term":"negative regulation of macrophage derived foam cell differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5266,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010749","Term":"regulation of nitric oxide mediated signal transduction","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5267,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010763","Term":"positive regulation of fibroblast migration","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5268,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010764","Term":"negative regulation of fibroblast migration","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5269,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010770","Term":"positive regulation of cell morphogenesis","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":5270,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010801","Term":"negative regulation of peptidyl-threonine phosphorylation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5271,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010831","Term":"positive regulation of myotube differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5272,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010838","Term":"positive regulation of keratinocyte proliferation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5273,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010842","Term":"retina layer formation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5274,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010867","Term":"positive regulation of triglyceride biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5275,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010894","Term":"negative regulation of steroid biosynthetic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5276,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010923","Term":"negative regulation of phosphatase activity","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5277,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010958","Term":"regulation of amino acid import across plasma membrane","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5278,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010962","Term":"regulation of glucan biosynthetic process","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5279,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010968","Term":"regulation of microtubule nucleation","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5280,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010984","Term":"regulation of lipoprotein particle clearance","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5281,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010988","Term":"regulation of low-density lipoprotein particle clearance","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5282,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010992","Term":"ubiquitin recycling","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5283,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0010998","Term":"regulation of translational initiation by eIF2 alpha phosphorylation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5284,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0014004","Term":"microglia differentiation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5285,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0014044","Term":"Schwann cell development","Annotated":37,"Significant":0,"Expected":2.23,"Rank in p.value_classic":5286,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0014887","Term":"cardiac muscle adaptation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5287,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0014898","Term":"cardiac muscle hypertrophy in response to stress","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5288,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0014904","Term":"myotube cell development","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5289,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015740","Term":"C4-dicarboxylate transport","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5290,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015780","Term":"nucleotide-sugar transmembrane transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5291,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015803","Term":"branched-chain amino acid transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5292,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015810","Term":"aspartate transmembrane transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5293,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015820","Term":"leucine transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5294,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015851","Term":"nucleobase transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5295,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015866","Term":"ADP transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5296,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015919","Term":"peroxisomal membrane transport","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5297,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015936","Term":"coenzyme A metabolic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5298,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0015937","Term":"coenzyme A biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5299,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016048","Term":"detection of temperature stimulus","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5300,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016073","Term":"snRNA metabolic process","Annotated":55,"Significant":0,"Expected":3.32,"Rank in p.value_classic":5301,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016074","Term":"sno(s)RNA metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5302,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016078","Term":"tRNA catabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5303,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016081","Term":"synaptic vesicle docking","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5304,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016093","Term":"polyprenol metabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5305,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016137","Term":"glycoside metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5306,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016180","Term":"snRNA processing","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5307,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016188","Term":"synaptic vesicle maturation","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5308,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016226","Term":"iron-sulfur cluster assembly","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5309,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016237","Term":"microautophagy","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5310,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016338","Term":"calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5311,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016479","Term":"negative regulation of transcription by RNA polymerase I","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5312,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016556","Term":"mRNA modification","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5313,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016558","Term":"protein import into peroxisome matrix","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5314,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0016973","Term":"poly(A)+ mRNA export from nucleus","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5315,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0017014","Term":"protein nitrosylation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5316,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0017062","Term":"respiratory chain complex III assembly","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5317,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018022","Term":"peptidyl-lysine methylation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5318,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018119","Term":"peptidyl-cysteine S-nitrosylation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5319,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018126","Term":"protein hydroxylation","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5320,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018146","Term":"keratan sulfate biosynthetic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5321,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018200","Term":"peptidyl-glutamic acid modification","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5322,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018206","Term":"peptidyl-methionine modification","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5323,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018208","Term":"peptidyl-proline modification","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5324,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018242","Term":"protein O-linked glycosylation via serine","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5325,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018342","Term":"protein prenylation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5326,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0018410","Term":"C-terminal protein amino acid modification","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5327,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019081","Term":"viral translation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5328,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019098","Term":"reproductive behavior","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5329,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019321","Term":"pentose metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5330,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019348","Term":"dolichol metabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5331,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019377","Term":"glycolipid catabolic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5332,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019471","Term":"4-hydroxyproline metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5333,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019511","Term":"peptidyl-proline hydroxylation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5334,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019646","Term":"aerobic electron transport chain","Annotated":85,"Significant":0,"Expected":5.13,"Rank in p.value_classic":5335,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019677","Term":"NAD catabolic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5336,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0019896","Term":"axonal transport of mitochondrion","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5337,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021517","Term":"ventral spinal cord development","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5338,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021522","Term":"spinal cord motor neuron differentiation","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5339,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021533","Term":"cell differentiation in hindbrain","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5340,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021542","Term":"dentate gyrus development","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5341,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021554","Term":"optic nerve development","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5342,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021694","Term":"cerebellar Purkinje cell layer formation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5343,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021819","Term":"layer formation in cerebral cortex","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5344,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021846","Term":"cell proliferation in forebrain","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5345,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021860","Term":"pyramidal neuron development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5346,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021871","Term":"forebrain regionalization","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5347,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0021904","Term":"dorsal/ventral neural tube patterning","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5348,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0022011","Term":"myelination in peripheral nervous system","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5349,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0022618","Term":"protein-RNA complex assembly","Annotated":196,"Significant":0,"Expected":11.84,"Rank in p.value_classic":5350,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030011","Term":"maintenance of cell polarity","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5351,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030150","Term":"protein import into mitochondrial matrix","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5352,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030157","Term":"pancreatic juice secretion","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5353,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030167","Term":"proteoglycan catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5354,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030201","Term":"heparan sulfate proteoglycan metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5355,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030202","Term":"heparin metabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5356,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030213","Term":"hyaluronan biosynthetic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5357,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030223","Term":"neutrophil differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5358,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030242","Term":"autophagy of peroxisome","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5359,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030325","Term":"adrenal gland development","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5360,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030488","Term":"tRNA methylation","Annotated":40,"Significant":0,"Expected":2.42,"Rank in p.value_classic":5361,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030490","Term":"maturation of SSU-rRNA","Annotated":54,"Significant":0,"Expected":3.26,"Rank in p.value_classic":5362,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030497","Term":"fatty acid elongation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5363,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030502","Term":"negative regulation of bone mineralization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5364,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030511","Term":"positive regulation of transforming growth factor beta receptor signaling pathway","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5365,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030539","Term":"male genitalia development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5366,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030656","Term":"regulation of vitamin metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5367,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030728","Term":"ovulation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5368,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030812","Term":"negative regulation of nucleotide catabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5369,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030838","Term":"positive regulation of actin filament polymerization","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5370,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030850","Term":"prostate gland development","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5371,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030859","Term":"polarized epithelial cell differentiation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5372,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030903","Term":"notochord development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5373,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030948","Term":"negative regulation of vascular endothelial growth factor receptor signaling pathway","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5374,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0030949","Term":"positive regulation of vascular endothelial growth factor receptor signaling pathway","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5375,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031000","Term":"response to caffeine","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5376,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031053","Term":"primary miRNA processing","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5377,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031054","Term":"pre-miRNA processing","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5378,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031069","Term":"hair follicle morphogenesis","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5379,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031076","Term":"embryonic camera-type eye development","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5380,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031112","Term":"positive regulation of microtubule polymerization or depolymerization","Annotated":34,"Significant":0,"Expected":2.05,"Rank in p.value_classic":5381,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031114","Term":"regulation of microtubule depolymerization","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5382,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031116","Term":"positive regulation of microtubule polymerization","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5383,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031123","Term":"RNA 3'-end processing","Annotated":93,"Significant":0,"Expected":5.62,"Rank in p.value_classic":5384,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031124","Term":"mRNA 3'-end processing","Annotated":50,"Significant":0,"Expected":3.02,"Rank in p.value_classic":5385,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031125","Term":"rRNA 3'-end processing","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5386,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031126","Term":"sno(s)RNA 3'-end processing","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5387,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031128","Term":"developmental induction","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5388,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031145","Term":"anaphase-promoting complex-dependent catabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5389,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031163","Term":"metallo-sulfur cluster assembly","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5390,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031167","Term":"rRNA methylation","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5391,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031268","Term":"pseudopodium organization","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5392,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031269","Term":"pseudopodium assembly","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5393,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031272","Term":"regulation of pseudopodium assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5394,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031274","Term":"positive regulation of pseudopodium assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5395,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031280","Term":"negative regulation of cyclase activity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5396,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031293","Term":"membrane protein intracellular domain proteolysis","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5397,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031365","Term":"N-terminal protein amino acid modification","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5398,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031424","Term":"keratinization","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5399,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031440","Term":"regulation of mRNA 3'-end processing","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5400,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031453","Term":"positive regulation of heterochromatin formation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5401,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031943","Term":"regulation of glucocorticoid metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5402,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0031998","Term":"regulation of fatty acid beta-oxidation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5403,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032011","Term":"ARF protein signal transduction","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5404,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032012","Term":"regulation of ARF protein signal transduction","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5405,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032025","Term":"response to cobalt ion","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5406,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032026","Term":"response to magnesium ion","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5407,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032042","Term":"mitochondrial DNA metabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5408,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032148","Term":"activation of protein kinase B activity","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5409,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032228","Term":"regulation of synaptic transmission, GABAergic","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5410,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032230","Term":"positive regulation of synaptic transmission, GABAergic","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5411,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032239","Term":"regulation of nucleobase-containing compound transport","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5412,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032261","Term":"purine nucleotide salvage","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5413,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032273","Term":"positive regulation of protein polymerization","Annotated":79,"Significant":0,"Expected":4.77,"Rank in p.value_classic":5414,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032292","Term":"peripheral nervous system axon ensheathment","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5415,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032328","Term":"alanine transport","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5416,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032331","Term":"negative regulation of chondrocyte differentiation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5417,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032332","Term":"positive regulation of chondrocyte differentiation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5418,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032367","Term":"intracellular cholesterol transport","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5419,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032369","Term":"negative regulation of lipid transport","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5420,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032400","Term":"melanosome localization","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5421,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032401","Term":"establishment of melanosome localization","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5422,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032402","Term":"melanosome transport","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5423,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032435","Term":"negative regulation of proteasomal ubiquitin-dependent protein catabolic process","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5424,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032482","Term":"Rab protein signal transduction","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5425,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032515","Term":"negative regulation of phosphoprotein phosphatase activity","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5426,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032516","Term":"positive regulation of phosphoprotein phosphatase activity","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5427,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032543","Term":"mitochondrial translation","Annotated":130,"Significant":0,"Expected":7.85,"Rank in p.value_classic":5428,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032754","Term":"positive regulation of interleukin-5 production","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5429,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032780","Term":"negative regulation of ATP-dependent activity","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5430,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032784","Term":"regulation of DNA-templated transcription elongation","Annotated":99,"Significant":0,"Expected":5.98,"Rank in p.value_classic":5431,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032785","Term":"negative regulation of DNA-templated transcription, elongation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5432,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032786","Term":"positive regulation of DNA-templated transcription, elongation","Annotated":58,"Significant":0,"Expected":3.5,"Rank in p.value_classic":5433,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032790","Term":"ribosome disassembly","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5434,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032793","Term":"positive regulation of CREB transcription factor activity","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5435,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032881","Term":"regulation of polysaccharide metabolic process","Annotated":35,"Significant":0,"Expected":2.11,"Rank in p.value_classic":5436,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032885","Term":"regulation of polysaccharide biosynthetic process","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5437,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032891","Term":"negative regulation of organic acid transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5438,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032924","Term":"activin receptor signaling pathway","Annotated":35,"Significant":0,"Expected":2.11,"Rank in p.value_classic":5439,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032925","Term":"regulation of activin receptor signaling pathway","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5440,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032926","Term":"negative regulation of activin receptor signaling pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5441,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032928","Term":"regulation of superoxide anion generation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5442,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032930","Term":"positive regulation of superoxide anion generation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5443,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032933","Term":"SREBP signaling pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5444,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032967","Term":"positive regulation of collagen biosynthetic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5445,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032968","Term":"positive regulation of transcription elongation by RNA polymerase II","Annotated":48,"Significant":0,"Expected":2.9,"Rank in p.value_classic":5446,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032981","Term":"mitochondrial respiratory chain complex I assembly","Annotated":60,"Significant":0,"Expected":3.62,"Rank in p.value_classic":5447,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032986","Term":"protein-DNA complex disassembly","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5448,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0032988","Term":"protein-RNA complex disassembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5449,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033119","Term":"negative regulation of RNA splicing","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5450,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033120","Term":"positive regulation of RNA splicing","Annotated":39,"Significant":0,"Expected":2.36,"Rank in p.value_classic":5451,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033122","Term":"negative regulation of purine nucleotide catabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5452,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033145","Term":"positive regulation of intracellular steroid hormone receptor signaling pathway","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5453,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033148","Term":"positive regulation of intracellular estrogen receptor signaling pathway","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5454,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033233","Term":"regulation of protein sumoylation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5455,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033235","Term":"positive regulation of protein sumoylation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5456,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033238","Term":"regulation of amine metabolic process","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5457,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033539","Term":"fatty acid beta-oxidation using acyl-CoA dehydrogenase","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5458,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033540","Term":"fatty acid beta-oxidation using acyl-CoA oxidase","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5459,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033689","Term":"negative regulation of osteoblast proliferation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5460,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033750","Term":"ribosome localization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5461,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033869","Term":"nucleoside bisphosphate catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5462,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0033962","Term":"P-body assembly","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5463,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034031","Term":"ribonucleoside bisphosphate catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5464,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034034","Term":"purine nucleoside bisphosphate catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5465,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034035","Term":"purine ribonucleoside bisphosphate metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5466,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034058","Term":"endosomal vesicle fusion","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5467,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034063","Term":"stress granule assembly","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5468,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034139","Term":"regulation of toll-like receptor 3 signaling pathway","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5469,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034243","Term":"regulation of transcription elongation by RNA polymerase II","Annotated":85,"Significant":0,"Expected":5.13,"Rank in p.value_classic":5470,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034244","Term":"negative regulation of transcription elongation by RNA polymerase II","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5471,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034314","Term":"Arp2/3 complex-mediated actin nucleation","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5472,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034315","Term":"regulation of Arp2/3 complex-mediated actin nucleation","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5473,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034333","Term":"adherens junction assembly","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5474,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034342","Term":"response to type III interferon","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5475,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034380","Term":"high-density lipoprotein particle assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5476,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034427","Term":"nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5477,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034453","Term":"microtubule anchoring","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5478,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034454","Term":"microtubule anchoring at centrosome","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5479,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034471","Term":"ncRNA 5'-end processing","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5480,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034472","Term":"snRNA 3'-end processing","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5481,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034497","Term":"protein localization to phagophore assembly site","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5482,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034551","Term":"mitochondrial respiratory chain complex III assembly","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5483,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034643","Term":"establishment of mitochondrion localization, microtubule-mediated","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5484,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034727","Term":"piecemeal microautophagy of the nucleus","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5485,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0034975","Term":"protein folding in endoplasmic reticulum","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5486,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035022","Term":"positive regulation of Rac protein signal transduction","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5487,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035036","Term":"sperm-egg recognition","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5488,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035090","Term":"maintenance of apical/basal cell polarity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5489,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035116","Term":"embryonic hindlimb morphogenesis","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5490,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035137","Term":"hindlimb morphogenesis","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5491,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035196","Term":"miRNA processing","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5492,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035305","Term":"negative regulation of dephosphorylation","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5493,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035308","Term":"negative regulation of protein dephosphorylation","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5494,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035330","Term":"regulation of hippo signaling","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5495,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035331","Term":"negative regulation of hippo signaling","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5496,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035335","Term":"peptidyl-tyrosine dephosphorylation","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5497,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035357","Term":"peroxisome proliferator activated receptor signaling pathway","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5498,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035358","Term":"regulation of peroxisome proliferator activated receptor signaling pathway","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5499,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035372","Term":"protein localization to microtubule","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5500,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035418","Term":"protein localization to synapse","Annotated":59,"Significant":0,"Expected":3.56,"Rank in p.value_classic":5501,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035437","Term":"maintenance of protein localization in endoplasmic reticulum","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5502,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035459","Term":"vesicle cargo loading","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5503,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035461","Term":"vitamin transmembrane transport","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5504,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035601","Term":"protein deacylation","Annotated":50,"Significant":0,"Expected":3.02,"Rank in p.value_classic":5505,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035646","Term":"endosome to melanosome transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5506,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035672","Term":"oligopeptide transmembrane transport","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5507,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035791","Term":"platelet-derived growth factor receptor-beta signaling pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5508,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035795","Term":"negative regulation of mitochondrial membrane permeability","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5509,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035821","Term":"modulation of process of another organism","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5510,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0035909","Term":"aorta morphogenesis","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5511,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036035","Term":"osteoclast development","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5512,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036065","Term":"fucosylation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5513,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036092","Term":"phosphatidylinositol-3-phosphate biosynthetic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5514,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036260","Term":"RNA capping","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5515,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036302","Term":"atrioventricular canal development","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5516,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036342","Term":"post-anal tail morphogenesis","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5517,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036444","Term":"calcium import into the mitochondrion","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5518,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036480","Term":"neuron intrinsic apoptotic signaling pathway in response to oxidative stress","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5519,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0036490","Term":"regulation of translation in response to endoplasmic reticulum stress","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5520,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0040015","Term":"negative regulation of multicellular organism growth","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5521,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042053","Term":"regulation of dopamine metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5522,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042069","Term":"regulation of catecholamine metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5523,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042159","Term":"lipoprotein catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5524,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042246","Term":"tissue regeneration","Annotated":55,"Significant":0,"Expected":3.32,"Rank in p.value_classic":5525,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042255","Term":"ribosome assembly","Annotated":57,"Significant":0,"Expected":3.44,"Rank in p.value_classic":5526,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042273","Term":"ribosomal large subunit biogenesis","Annotated":72,"Significant":0,"Expected":4.35,"Rank in p.value_classic":5527,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042274","Term":"ribosomal small subunit biogenesis","Annotated":101,"Significant":0,"Expected":6.1,"Rank in p.value_classic":5528,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042308","Term":"negative regulation of protein import into nucleus","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5529,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042339","Term":"keratan sulfate metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5530,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042362","Term":"fat-soluble vitamin biosynthetic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5531,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042364","Term":"water-soluble vitamin biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5532,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042407","Term":"cristae formation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5533,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042447","Term":"hormone catabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5534,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042461","Term":"photoreceptor cell development","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5535,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042462","Term":"eye photoreceptor cell development","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5536,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042492","Term":"gamma-delta T cell differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5537,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042574","Term":"retinal metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5538,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042634","Term":"regulation of hair cycle","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5539,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042744","Term":"hydrogen peroxide catabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5540,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042761","Term":"very long-chain fatty acid biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5541,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042776","Term":"proton motive force-driven mitochondrial ATP synthesis","Annotated":66,"Significant":0,"Expected":3.99,"Rank in p.value_classic":5542,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042790","Term":"nucleolar large rRNA transcription by RNA polymerase I","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5543,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042795","Term":"snRNA transcription by RNA polymerase II","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5544,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042797","Term":"tRNA transcription by RNA polymerase III","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5545,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042921","Term":"glucocorticoid receptor signaling pathway","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5546,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042939","Term":"tripeptide transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5547,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0042953","Term":"lipoprotein transport","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5548,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043045","Term":"post-fertilization epigenetic regulation of gene expression","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5549,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043117","Term":"positive regulation of vascular permeability","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5550,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043144","Term":"sno(s)RNA processing","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5551,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043173","Term":"nucleotide salvage","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5552,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043217","Term":"myelin maintenance","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5553,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043247","Term":"telomere maintenance in response to DNA damage","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5554,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043306","Term":"positive regulation of mast cell degranulation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5555,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043312","Term":"neutrophil degranulation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5556,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043328","Term":"protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5557,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043353","Term":"enucleate erythrocyte differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5558,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043403","Term":"skeletal muscle tissue regeneration","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5559,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043457","Term":"regulation of cellular respiration","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5560,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043476","Term":"pigment accumulation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5561,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043482","Term":"cellular pigment accumulation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5562,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043484","Term":"regulation of RNA splicing","Annotated":165,"Significant":0,"Expected":9.97,"Rank in p.value_classic":5563,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043485","Term":"endosome to pigment granule transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5564,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043508","Term":"negative regulation of JUN kinase activity","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5565,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043555","Term":"regulation of translation in response to stress","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5566,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043558","Term":"regulation of translational initiation in response to stress","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5567,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043567","Term":"regulation of insulin-like growth factor receptor signaling pathway","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5568,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043574","Term":"peroxisomal transport","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5569,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043576","Term":"regulation of respiratory gaseous exchange","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5570,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043586","Term":"tongue development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5571,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043589","Term":"skin morphogenesis","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5572,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043605","Term":"amide catabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5573,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043651","Term":"linoleic acid metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5574,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043653","Term":"mitochondrial fragmentation involved in apoptotic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5575,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043666","Term":"regulation of phosphoprotein phosphatase activity","Annotated":40,"Significant":0,"Expected":2.42,"Rank in p.value_classic":5576,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043691","Term":"reverse cholesterol transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5577,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043923","Term":"positive regulation by host of viral transcription","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5578,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0043928","Term":"exonucleolytic catabolism of deadenylated mRNA","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5579,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044030","Term":"regulation of DNA methylation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5580,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044065","Term":"regulation of respiratory system process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5581,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044571","Term":"[2Fe-2S] cluster assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5582,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044743","Term":"protein transmembrane import into intracellular organelle","Annotated":34,"Significant":0,"Expected":2.05,"Rank in p.value_classic":5583,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044804","Term":"nucleophagy","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5584,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044848","Term":"biological phase","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5585,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044849","Term":"estrous cycle","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5586,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0044872","Term":"lipoprotein localization","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5587,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045039","Term":"protein insertion into mitochondrial inner membrane","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5588,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045040","Term":"protein insertion into mitochondrial outer membrane","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5589,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045047","Term":"protein targeting to ER","Annotated":38,"Significant":0,"Expected":2.3,"Rank in p.value_classic":5590,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045048","Term":"protein insertion into ER membrane","Annotated":31,"Significant":0,"Expected":1.87,"Rank in p.value_classic":5591,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045050","Term":"protein insertion into ER membrane by stop-transfer membrane-anchor sequence","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5592,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045056","Term":"transcytosis","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5593,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045117","Term":"azole transmembrane transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5594,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045197","Term":"establishment or maintenance of epithelial cell apical/basal polarity","Annotated":48,"Significant":0,"Expected":2.9,"Rank in p.value_classic":5595,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045198","Term":"establishment of epithelial cell apical/basal polarity","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5596,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045199","Term":"maintenance of epithelial cell apical/basal polarity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5597,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045292","Term":"mRNA cis splicing, via spliceosome","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5598,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045475","Term":"locomotor rhythm","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5599,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045540","Term":"regulation of cholesterol biosynthetic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5600,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045721","Term":"negative regulation of gluconeogenesis","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5601,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045722","Term":"positive regulation of gluconeogenesis","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5602,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045724","Term":"positive regulation of cilium assembly","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5603,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045725","Term":"positive regulation of glycogen biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5604,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045736","Term":"negative regulation of cyclin-dependent protein serine/threonine kinase activity","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5605,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045737","Term":"positive regulation of cyclin-dependent protein serine/threonine kinase activity","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5606,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045777","Term":"positive regulation of blood pressure","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5607,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045820","Term":"negative regulation of glycolytic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5608,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045842","Term":"positive regulation of mitotic metaphase/anaphase transition","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5609,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045906","Term":"negative regulation of vasoconstriction","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5610,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045939","Term":"negative regulation of steroid metabolic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5611,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045943","Term":"positive regulation of transcription by RNA polymerase I","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":5612,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045945","Term":"positive regulation of transcription by RNA polymerase III","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5613,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0045986","Term":"negative regulation of smooth muscle contraction","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5614,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046036","Term":"CTP metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5615,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046037","Term":"GMP metabolic process","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5616,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046040","Term":"IMP metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5617,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046112","Term":"nucleobase biosynthetic process","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5618,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046185","Term":"aldehyde catabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5619,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046326","Term":"positive regulation of glucose import","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5620,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046348","Term":"amino sugar catabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5621,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046349","Term":"amino sugar biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5622,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046479","Term":"glycosphingolipid catabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5623,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046500","Term":"S-adenosylmethionine metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5624,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046504","Term":"glycerol ether biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5625,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046512","Term":"sphingosine biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5626,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046514","Term":"ceramide catabolic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5627,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046520","Term":"sphingoid biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5628,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046530","Term":"photoreceptor cell differentiation","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5629,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046580","Term":"negative regulation of Ras protein signal transduction","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5630,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046621","Term":"negative regulation of organ growth","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5631,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046628","Term":"positive regulation of insulin receptor signaling pathway","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5632,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046710","Term":"GDP metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5633,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046823","Term":"negative regulation of nucleocytoplasmic transport","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5634,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046827","Term":"positive regulation of protein export from nucleus","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5635,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046831","Term":"regulation of RNA export from nucleus","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5636,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046835","Term":"carbohydrate phosphorylation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5637,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0046856","Term":"phosphatidylinositol dephosphorylation","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5638,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0047497","Term":"mitochondrion transport along microtubule","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5639,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048015","Term":"phosphatidylinositol-mediated signaling","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5640,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048024","Term":"regulation of mRNA splicing, via spliceosome","Annotated":95,"Significant":0,"Expected":5.74,"Rank in p.value_classic":5641,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048025","Term":"negative regulation of mRNA splicing, via spliceosome","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5642,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048026","Term":"positive regulation of mRNA splicing, via spliceosome","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5643,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048048","Term":"embryonic eye morphogenesis","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5644,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048143","Term":"astrocyte activation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5645,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048172","Term":"regulation of short-term neuronal synaptic plasticity","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5646,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048194","Term":"Golgi vesicle budding","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5647,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048199","Term":"vesicle targeting, to, from or within Golgi","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5648,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048207","Term":"vesicle targeting, rough ER to cis-Golgi","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5649,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048208","Term":"COPII vesicle coating","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5650,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048240","Term":"sperm capacitation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5651,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048251","Term":"elastic fiber assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5652,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048286","Term":"lung alveolus development","Annotated":44,"Significant":0,"Expected":2.66,"Rank in p.value_classic":5653,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048339","Term":"paraxial mesoderm development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5654,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048368","Term":"lateral mesoderm development","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5655,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048388","Term":"endosomal lumen acidification","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5656,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048557","Term":"embryonic digestive tract morphogenesis","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5657,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048566","Term":"embryonic digestive tract development","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5658,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048596","Term":"embryonic camera-type eye morphogenesis","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5659,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048701","Term":"embryonic cranial skeleton morphogenesis","Annotated":39,"Significant":0,"Expected":2.36,"Rank in p.value_classic":5660,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048704","Term":"embryonic skeletal system morphogenesis","Annotated":70,"Significant":0,"Expected":4.23,"Rank in p.value_classic":5661,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048711","Term":"positive regulation of astrocyte differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5662,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048714","Term":"positive regulation of oligodendrocyte differentiation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5663,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048715","Term":"negative regulation of oligodendrocyte differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5664,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048741","Term":"skeletal muscle fiber development","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5665,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048745","Term":"smooth muscle tissue development","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5666,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048757","Term":"pigment granule maturation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5667,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0048820","Term":"hair follicle maturation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5668,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050427","Term":"3'-phosphoadenosine 5'-phosphosulfate metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5669,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050482","Term":"arachidonic acid secretion","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5670,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050667","Term":"homocysteine metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5671,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050684","Term":"regulation of mRNA processing","Annotated":116,"Significant":0,"Expected":7.01,"Rank in p.value_classic":5672,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050685","Term":"positive regulation of mRNA processing","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5673,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050686","Term":"negative regulation of mRNA processing","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5674,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050746","Term":"regulation of lipoprotein metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5675,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050775","Term":"positive regulation of dendrite morphogenesis","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5676,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050847","Term":"progesterone receptor signaling pathway","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5677,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050908","Term":"detection of light stimulus involved in visual perception","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5678,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050910","Term":"detection of mechanical stimulus involved in sensory perception of sound","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5679,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050951","Term":"sensory perception of temperature stimulus","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5680,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050961","Term":"detection of temperature stimulus involved in sensory perception","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5681,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050962","Term":"detection of light stimulus involved in sensory perception","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5682,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050965","Term":"detection of temperature stimulus involved in sensory perception of pain","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5683,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050966","Term":"detection of mechanical stimulus involved in sensory perception of pain","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5684,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050974","Term":"detection of mechanical stimulus involved in sensory perception","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5685,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0050996","Term":"positive regulation of lipid catabolic process","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5686,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051036","Term":"regulation of endosome size","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5687,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051081","Term":"nuclear membrane disassembly","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5688,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051095","Term":"regulation of helicase activity","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5689,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051123","Term":"RNA polymerase II preinitiation complex assembly","Annotated":54,"Significant":0,"Expected":3.26,"Rank in p.value_classic":5690,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051131","Term":"chaperone-mediated protein complex assembly","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5691,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051150","Term":"regulation of smooth muscle cell differentiation","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5692,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051151","Term":"negative regulation of smooth muscle cell differentiation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5693,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051152","Term":"positive regulation of smooth muscle cell differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5694,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051220","Term":"cytoplasmic sequestering of protein","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5695,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051292","Term":"nuclear pore complex assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5696,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051350","Term":"negative regulation of lyase activity","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5697,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051409","Term":"response to nitrosative stress","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5698,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051443","Term":"positive regulation of ubiquitin-protein transferase activity","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5699,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051451","Term":"myoblast migration","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5700,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051647","Term":"nucleus localization","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5701,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051654","Term":"establishment of mitochondrion localization","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5702,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051657","Term":"maintenance of organelle location","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5703,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051764","Term":"actin crosslink formation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5704,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051775","Term":"response to redox state","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5705,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051788","Term":"response to misfolded protein","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5706,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051797","Term":"regulation of hair follicle development","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5707,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051798","Term":"positive regulation of hair follicle development","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5708,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051875","Term":"pigment granule localization","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5709,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051904","Term":"pigment granule transport","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5710,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051905","Term":"establishment of pigment granule localization","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5711,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051923","Term":"sulfation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5712,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051930","Term":"regulation of sensory perception of pain","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5713,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051931","Term":"regulation of sensory perception","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5714,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051953","Term":"negative regulation of amine transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5715,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0051956","Term":"negative regulation of amino acid transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5716,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0055003","Term":"cardiac myofibril assembly","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5717,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0055010","Term":"ventricular cardiac muscle tissue morphogenesis","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5718,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0055022","Term":"negative regulation of cardiac muscle tissue growth","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5719,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0055057","Term":"neuroblast division","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5720,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0055091","Term":"phospholipid homeostasis","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5721,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060004","Term":"reflex","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5722,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060008","Term":"Sertoli cell differentiation","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5723,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060009","Term":"Sertoli cell development","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5724,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060019","Term":"radial glial cell differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5725,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060020","Term":"Bergmann glial cell differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5726,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060026","Term":"convergent extension","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5727,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060039","Term":"pericardium development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5728,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060055","Term":"angiogenesis involved in wound healing","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5729,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060065","Term":"uterus development","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5730,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060088","Term":"auditory receptor cell stereocilium organization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5731,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060122","Term":"inner ear receptor cell stereocilium organization","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5732,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060147","Term":"regulation of post-transcriptional gene silencing","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5733,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060148","Term":"positive regulation of post-transcriptional gene silencing","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5734,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060149","Term":"negative regulation of post-transcriptional gene silencing","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5735,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060192","Term":"negative regulation of lipase activity","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5736,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060211","Term":"regulation of nuclear-transcribed mRNA poly(A) tail shortening","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5737,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060213","Term":"positive regulation of nuclear-transcribed mRNA poly(A) tail shortening","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5738,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060219","Term":"camera-type eye photoreceptor cell differentiation","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5739,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060221","Term":"retinal rod cell differentiation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5740,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060260","Term":"regulation of transcription initiation by RNA polymerase II","Annotated":71,"Significant":0,"Expected":4.29,"Rank in p.value_classic":5741,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060261","Term":"positive regulation of transcription initiation by RNA polymerase II","Annotated":60,"Significant":0,"Expected":3.62,"Rank in p.value_classic":5742,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060295","Term":"regulation of cilium movement involved in cell motility","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5743,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060317","Term":"cardiac epithelial to mesenchymal transition","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5744,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060343","Term":"trabecula formation","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5745,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060347","Term":"heart trabecula formation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5746,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060352","Term":"cell adhesion molecule production","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5747,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060379","Term":"cardiac muscle cell myoblast differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5748,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060382","Term":"regulation of DNA strand elongation","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5749,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060392","Term":"negative regulation of SMAD protein signal transduction","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5750,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060412","Term":"ventricular septum morphogenesis","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5751,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060413","Term":"atrial septum morphogenesis","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5752,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060502","Term":"epithelial cell proliferation involved in lung morphogenesis","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5753,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060512","Term":"prostate gland morphogenesis","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5754,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060546","Term":"negative regulation of necroptotic process","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5755,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060571","Term":"morphogenesis of an epithelial fold","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5756,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060572","Term":"morphogenesis of an epithelial bud","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5757,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060602","Term":"branch elongation of an epithelium","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5758,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060669","Term":"embryonic placenta morphogenesis","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5759,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060670","Term":"branching involved in labyrinthine layer morphogenesis","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5760,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060713","Term":"labyrinthine layer morphogenesis","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5761,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060740","Term":"prostate gland epithelium morphogenesis","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5762,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060767","Term":"epithelial cell proliferation involved in prostate gland development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5763,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060841","Term":"venous blood vessel development","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5764,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060964","Term":"regulation of miRNA-mediated gene silencing","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5765,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060965","Term":"negative regulation of miRNA-mediated gene silencing","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5766,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060966","Term":"regulation of gene silencing by regulatory ncRNA","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5767,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0060967","Term":"negative regulation of gene silencing by regulatory ncRNA","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5768,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061003","Term":"positive regulation of dendritic spine morphogenesis","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5769,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061029","Term":"eyelid development in camera-type eye","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5770,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061036","Term":"positive regulation of cartilage development","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5771,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061037","Term":"negative regulation of cartilage development","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5772,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061042","Term":"vascular wound healing","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5773,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061043","Term":"regulation of vascular wound healing","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5774,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061101","Term":"neuroendocrine cell differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5775,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061117","Term":"negative regulation of heart growth","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5776,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061450","Term":"trophoblast cell migration","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5777,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061615","Term":"glycolytic process through fructose-6-phosphate","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5778,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061620","Term":"glycolytic process through glucose-6-phosphate","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5779,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061621","Term":"canonical glycolysis","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5780,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061668","Term":"mitochondrial ribosome assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5781,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061709","Term":"reticulophagy","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5782,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061718","Term":"glucose catabolic process to pyruvate","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5783,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061723","Term":"glycophagy","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5784,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0061795","Term":"Golgi lumen acidification","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5785,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0062042","Term":"regulation of cardiac epithelial to mesenchymal transition","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5786,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0062099","Term":"negative regulation of programmed necrotic cell death","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5787,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0062125","Term":"regulation of mitochondrial gene expression","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5788,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0062149","Term":"detection of stimulus involved in sensory perception of pain","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":5789,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0062237","Term":"protein localization to postsynapse","Annotated":34,"Significant":0,"Expected":2.05,"Rank in p.value_classic":5790,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0065002","Term":"intracellular protein transmembrane transport","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5791,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070071","Term":"proton-transporting two-sector ATPase complex assembly","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5792,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070129","Term":"regulation of mitochondrial translation","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5793,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070131","Term":"positive regulation of mitochondrial translation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5794,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070168","Term":"negative regulation of biomineral tissue development","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5795,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070198","Term":"protein localization to chromosome, telomeric region","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5796,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070199","Term":"establishment of protein localization to chromosome","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5797,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070200","Term":"establishment of protein localization to telomere","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5798,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070202","Term":"regulation of establishment of protein localization to chromosome","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5799,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070203","Term":"regulation of establishment of protein localization to telomere","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5800,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070262","Term":"peptidyl-serine dephosphorylation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5801,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070278","Term":"extracellular matrix constituent secretion","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5802,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070307","Term":"lens fiber cell development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5803,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070314","Term":"G1 to G0 transition","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5804,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070424","Term":"regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5805,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070525","Term":"tRNA threonylcarbamoyladenosine metabolic process","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5806,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070562","Term":"regulation of vitamin D receptor signaling pathway","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5807,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070729","Term":"cyclic nucleotide transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5808,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070778","Term":"L-aspartate transmembrane transport","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5809,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070863","Term":"positive regulation of protein exit from endoplasmic reticulum","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5810,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070873","Term":"regulation of glycogen metabolic process","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":5811,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070875","Term":"positive regulation of glycogen metabolic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5812,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070886","Term":"positive regulation of calcineurin-NFAT signaling cascade","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5813,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070897","Term":"transcription preinitiation complex assembly","Annotated":66,"Significant":0,"Expected":3.99,"Rank in p.value_classic":5814,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070900","Term":"mitochondrial tRNA modification","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5815,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070914","Term":"UV-damage excision repair","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5816,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070920","Term":"regulation of regulatory ncRNA processing","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5817,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070922","Term":"RISC complex assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5818,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070934","Term":"CRD-mediated mRNA stabilization","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5819,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0070989","Term":"oxidative demethylation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5820,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071071","Term":"regulation of phospholipid biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5821,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071108","Term":"protein K48-linked deubiquitination","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5822,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071166","Term":"ribonucleoprotein complex localization","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5823,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071218","Term":"cellular response to misfolded protein","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5824,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071236","Term":"cellular response to antibiotic","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5825,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071257","Term":"cellular response to electrical stimulus","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5826,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071285","Term":"cellular response to lithium ion","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5827,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071415","Term":"cellular response to purine-containing compound","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5828,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071472","Term":"cellular response to salt stress","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5829,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071474","Term":"cellular hyperosmotic response","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5830,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071481","Term":"cellular response to X-ray","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5831,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071493","Term":"cellular response to UV-B","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5832,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071501","Term":"cellular response to sterol depletion","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5833,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071514","Term":"genomic imprinting","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5834,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071542","Term":"dopaminergic neuron differentiation","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":5835,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071577","Term":"zinc ion transmembrane transport","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5836,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071635","Term":"negative regulation of transforming growth factor beta production","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5837,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071806","Term":"protein transmembrane transport","Annotated":59,"Significant":0,"Expected":3.56,"Rank in p.value_classic":5838,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071816","Term":"tail-anchored membrane protein insertion into ER membrane","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5839,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071826","Term":"protein-RNA complex organization","Annotated":206,"Significant":0,"Expected":12.44,"Rank in p.value_classic":5840,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0071895","Term":"odontoblast differentiation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5841,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072079","Term":"nephron tubule formation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5842,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072109","Term":"glomerular mesangium development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5843,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072110","Term":"glomerular mesangial cell proliferation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5844,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072132","Term":"mesenchyme morphogenesis","Annotated":46,"Significant":0,"Expected":2.78,"Rank in p.value_classic":5845,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072176","Term":"nephric duct development","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5846,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072224","Term":"metanephric glomerulus development","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5847,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072329","Term":"monocarboxylic acid catabolic process","Annotated":105,"Significant":0,"Expected":6.34,"Rank in p.value_classic":5848,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072344","Term":"rescue of stalled ribosome","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5849,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072350","Term":"tricarboxylic acid metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5850,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072393","Term":"microtubule anchoring at microtubule organizing center","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5851,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072497","Term":"mesenchymal stem cell differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5852,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072498","Term":"embryonic skeletal joint development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5853,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072520","Term":"seminiferous tubule development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5854,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072530","Term":"purine-containing compound transmembrane transport","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5855,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072531","Term":"pyrimidine-containing compound transmembrane transport","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5856,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072537","Term":"fibroblast activation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5857,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072578","Term":"neurotransmitter-gated ion channel clustering","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5858,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072584","Term":"caveolin-mediated endocytosis","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5859,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072599","Term":"establishment of protein localization to endoplasmic reticulum","Annotated":41,"Significant":0,"Expected":2.48,"Rank in p.value_classic":5860,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072662","Term":"protein localization to peroxisome","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5861,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072663","Term":"establishment of protein localization to peroxisome","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5862,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072666","Term":"establishment of protein localization to vacuole","Annotated":57,"Significant":0,"Expected":3.44,"Rank in p.value_classic":5863,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072697","Term":"protein localization to cell cortex","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5864,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072710","Term":"response to hydroxyurea","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5865,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0072711","Term":"cellular response to hydroxyurea","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5866,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0075522","Term":"IRES-dependent viral translational initiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5867,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0080009","Term":"mRNA methylation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5868,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0086069","Term":"bundle of His cell to Purkinje myocyte communication","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5869,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090042","Term":"tubulin deacetylation","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5870,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090043","Term":"regulation of tubulin deacetylation","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5871,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090083","Term":"regulation of inclusion body assembly","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5872,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090084","Term":"negative regulation of inclusion body assembly","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5873,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090110","Term":"COPII-coated vesicle cargo loading","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5874,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090114","Term":"COPII-coated vesicle budding","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":5875,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090128","Term":"regulation of synapse maturation","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5876,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090141","Term":"positive regulation of mitochondrial fission","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5877,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090151","Term":"establishment of protein localization to mitochondrial membrane","Annotated":34,"Significant":0,"Expected":2.05,"Rank in p.value_classic":5878,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090153","Term":"regulation of sphingolipid biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5879,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090160","Term":"Golgi to lysosome transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5880,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090175","Term":"regulation of establishment of planar polarity","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5881,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090177","Term":"establishment of planar polarity involved in neural tube closure","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5882,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090178","Term":"regulation of establishment of planar polarity involved in neural tube closure","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5883,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090205","Term":"positive regulation of cholesterol metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5884,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090208","Term":"positive regulation of triglyceride metabolic process","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5885,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090209","Term":"negative regulation of triglyceride metabolic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5886,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090280","Term":"positive regulation of calcium ion import","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5887,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090281","Term":"negative regulation of calcium ion import","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5888,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090308","Term":"regulation of DNA methylation-dependent heterochromatin formation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5889,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090309","Term":"positive regulation of DNA methylation-dependent heterochromatin formation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5890,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090311","Term":"regulation of protein deacetylation","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5891,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090313","Term":"regulation of protein targeting to membrane","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5892,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090314","Term":"positive regulation of protein targeting to membrane","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5893,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090399","Term":"replicative senescence","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5894,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090435","Term":"protein localization to nuclear envelope","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5895,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090481","Term":"pyrimidine nucleotide-sugar transmembrane transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5896,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090493","Term":"catecholamine uptake","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5897,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090494","Term":"dopamine uptake","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5898,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090594","Term":"inflammatory response to wounding","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5899,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090646","Term":"mitochondrial tRNA processing","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5900,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090670","Term":"RNA localization to Cajal body","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5901,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090671","Term":"telomerase RNA localization to Cajal body","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5902,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090672","Term":"telomerase RNA localization","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5903,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0090685","Term":"RNA localization to nucleus","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5904,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0095500","Term":"acetylcholine receptor signaling pathway","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":5905,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097062","Term":"dendritic spine maintenance","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5906,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097091","Term":"synaptic vesicle clustering","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5907,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097106","Term":"postsynaptic density organization","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5908,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097107","Term":"postsynaptic density assembly","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5909,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097120","Term":"receptor localization to synapse","Annotated":49,"Significant":0,"Expected":2.96,"Rank in p.value_classic":5910,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097154","Term":"GABAergic neuron differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5911,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097164","Term":"ammonium ion metabolic process","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5912,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097284","Term":"hepatocyte apoptotic process","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5913,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097320","Term":"plasma membrane tubulation","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5914,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097345","Term":"mitochondrial outer membrane permeabilization","Annotated":30,"Significant":0,"Expected":1.81,"Rank in p.value_classic":5915,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097354","Term":"prenylation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5916,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097384","Term":"cellular lipid biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5917,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097401","Term":"synaptic vesicle lumen acidification","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5918,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097428","Term":"protein maturation by iron-sulfur cluster transfer","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5919,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0097709","Term":"connective tissue replacement","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5920,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098528","Term":"skeletal muscle fiber differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5921,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098693","Term":"regulation of synaptic vesicle cycle","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5922,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098696","Term":"regulation of neurotransmitter receptor localization to postsynaptic specialization membrane","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5923,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098698","Term":"postsynaptic specialization assembly","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5924,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098703","Term":"calcium ion import across plasma membrane","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":5925,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098719","Term":"sodium ion import across plasma membrane","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5926,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098732","Term":"macromolecule deacylation","Annotated":54,"Significant":0,"Expected":3.26,"Rank in p.value_classic":5927,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098734","Term":"macromolecule depalmitoylation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5928,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098743","Term":"cell aggregation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5929,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098751","Term":"bone cell development","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5930,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098760","Term":"response to interleukin-7","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5931,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098761","Term":"cellular response to interleukin-7","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5932,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098840","Term":"protein transport along microtubule","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5933,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098877","Term":"neurotransmitter receptor transport to plasma membrane","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5934,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098887","Term":"neurotransmitter receptor transport, endosome to postsynaptic membrane","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5935,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098911","Term":"regulation of ventricular cardiac muscle cell action potential","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5936,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098935","Term":"dendritic transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5937,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098969","Term":"neurotransmitter receptor transport to postsynaptic membrane","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5938,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0098974","Term":"postsynaptic actin cytoskeleton organization","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5939,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099022","Term":"vesicle tethering","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":5940,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099068","Term":"postsynapse assembly","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5941,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099084","Term":"postsynaptic specialization organization","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":5942,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099116","Term":"tRNA 5'-end processing","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5943,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099118","Term":"microtubule-based protein transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5944,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099150","Term":"regulation of postsynaptic specialization assembly","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5945,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099151","Term":"regulation of postsynaptic density assembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5946,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099505","Term":"regulation of presynaptic membrane potential","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5947,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099633","Term":"protein localization to postsynaptic specialization membrane","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5948,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099637","Term":"neurotransmitter receptor transport","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5949,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099638","Term":"endosome to plasma membrane protein transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5950,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099639","Term":"neurotransmitter receptor transport, endosome to plasma membrane","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5951,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0099645","Term":"neurotransmitter receptor localization to postsynaptic specialization membrane","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5952,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0101024","Term":"mitotic nuclear membrane organization","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5953,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0106058","Term":"positive regulation of calcineurin-mediated signaling","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5954,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0106074","Term":"aminoacyl-tRNA metabolism involved in translational fidelity","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5955,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0106118","Term":"regulation of sterol biosynthetic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5956,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0110011","Term":"regulation of basement membrane organization","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5957,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0110096","Term":"cellular response to aldehyde","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5958,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0110154","Term":"RNA decapping","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":5959,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0110156","Term":"methylguanosine-cap decapping","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5960,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0120263","Term":"positive regulation of heterochromatin organization","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5961,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0120316","Term":"sperm flagellum assembly","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":5962,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0140052","Term":"cellular response to oxidised low-density lipoprotein particle stimulus","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5963,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0140053","Term":"mitochondrial gene expression","Annotated":164,"Significant":0,"Expected":9.9,"Rank in p.value_classic":5964,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0140588","Term":"chromatin looping","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5965,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0150011","Term":"regulation of neuron projection arborization","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5966,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0150079","Term":"negative regulation of neuroinflammatory response","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5967,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0150172","Term":"regulation of phosphatidylcholine metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5968,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0170043","Term":"non-proteinogenic amino acid biosynthetic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5969,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:0170044","Term":"non-proteinogenic amino acid catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5970,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900006","Term":"positive regulation of dendrite development","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5971,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900029","Term":"positive regulation of ruffle assembly","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5972,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900034","Term":"regulation of cellular response to heat","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":5973,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900037","Term":"regulation of cellular response to hypoxia","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":5974,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900078","Term":"positive regulation of cellular response to insulin stimulus","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5975,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900102","Term":"negative regulation of endoplasmic reticulum unfolded protein response","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5976,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900115","Term":"extracellular regulation of signal transduction","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5977,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900116","Term":"extracellular negative regulation of signal transduction","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5978,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900151","Term":"regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5979,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900152","Term":"negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5980,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900153","Term":"positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5981,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900181","Term":"negative regulation of protein localization to nucleus","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":5982,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900221","Term":"regulation of amyloid-beta clearance","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":5983,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900273","Term":"positive regulation of long-term synaptic potentiation","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":5984,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900368","Term":"regulation of post-transcriptional gene silencing by regulatory ncRNA","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":5985,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900369","Term":"negative regulation of post-transcriptional gene silencing by regulatory ncRNA","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5986,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900370","Term":"positive regulation of post-transcriptional gene silencing by RNA","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5987,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900452","Term":"regulation of long-term synaptic depression","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5988,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1900864","Term":"mitochondrial RNA modification","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5989,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901028","Term":"regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":5990,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901029","Term":"negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":5991,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901071","Term":"glucosamine-containing compound metabolic process","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":5992,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901160","Term":"primary amino compound metabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":5993,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901163","Term":"regulation of trophoblast cell migration","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5994,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901503","Term":"ether biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5995,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901533","Term":"negative regulation of hematopoietic progenitor cell differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":5996,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901569","Term":"fatty acid derivative catabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":5997,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901663","Term":"quinone biosynthetic process","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":5998,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901679","Term":"nucleotide transmembrane transport","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":5999,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901722","Term":"regulation of cell proliferation involved in kidney development","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":6000,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901836","Term":"regulation of transcription of nucleolar large rRNA by RNA polymerase I","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6001,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901838","Term":"positive regulation of transcription of nucleolar large rRNA by RNA polymerase I","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6002,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901857","Term":"positive regulation of cellular respiration","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6003,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1901862","Term":"negative regulation of muscle tissue development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6004,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902019","Term":"regulation of cilium-dependent cell motility","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6005,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902065","Term":"response to L-glutamate","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":6006,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902101","Term":"positive regulation of metaphase/anaphase transition of cell cycle","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":6007,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902175","Term":"regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","Annotated":36,"Significant":0,"Expected":2.17,"Rank in p.value_classic":6008,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902176","Term":"negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":6009,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902337","Term":"regulation of apoptotic process involved in morphogenesis","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6010,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902430","Term":"negative regulation of amyloid-beta formation","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":6011,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902455","Term":"negative regulation of stem cell population maintenance","Annotated":22,"Significant":0,"Expected":1.33,"Rank in p.value_classic":6012,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902473","Term":"regulation of protein localization to synapse","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":6013,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902513","Term":"regulation of organelle transport along microtubule","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6014,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902644","Term":"tertiary alcohol metabolic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6015,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902653","Term":"secondary alcohol biosynthetic process","Annotated":46,"Significant":0,"Expected":2.78,"Rank in p.value_classic":6016,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902656","Term":"calcium ion import into cytosol","Annotated":28,"Significant":0,"Expected":1.69,"Rank in p.value_classic":6017,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902683","Term":"regulation of receptor localization to synapse","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":6018,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902855","Term":"regulation of non-motile cilium assembly","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6019,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902894","Term":"negative regulation of miRNA transcription","Annotated":26,"Significant":0,"Expected":1.57,"Rank in p.value_classic":6020,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902950","Term":"regulation of dendritic spine maintenance","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6021,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1902992","Term":"negative regulation of amyloid precursor protein catabolic process","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":6022,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903059","Term":"regulation of protein lipidation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6023,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903232","Term":"melanosome assembly","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":6024,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903236","Term":"regulation of leukocyte tethering or rolling","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6025,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903238","Term":"positive regulation of leukocyte tethering or rolling","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6026,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903241","Term":"U2-type prespliceosome assembly","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":6027,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903376","Term":"regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":6028,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903377","Term":"negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6029,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903405","Term":"protein localization to nuclear body","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6030,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903428","Term":"positive regulation of reactive oxygen species biosynthetic process","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6031,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903441","Term":"protein localization to ciliary membrane","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6032,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903539","Term":"protein localization to postsynaptic membrane","Annotated":33,"Significant":0,"Expected":1.99,"Rank in p.value_classic":6033,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903540","Term":"establishment of protein localization to postsynaptic membrane","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":6034,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903564","Term":"regulation of protein localization to cilium","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6035,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903624","Term":"regulation of DNA catabolic process","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6036,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903689","Term":"regulation of wound healing, spreading of epidermal cells","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6037,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903715","Term":"regulation of aerobic respiration","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":6038,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903725","Term":"regulation of phospholipid metabolic process","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":6039,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903789","Term":"regulation of amino acid transmembrane transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6040,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903798","Term":"regulation of miRNA processing","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6041,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903830","Term":"magnesium ion transmembrane transport","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":6042,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903846","Term":"positive regulation of cellular response to transforming growth factor beta stimulus","Annotated":29,"Significant":0,"Expected":1.75,"Rank in p.value_classic":6043,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1903963","Term":"arachidonate transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6044,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904030","Term":"negative regulation of cyclin-dependent protein kinase activity","Annotated":20,"Significant":0,"Expected":1.21,"Rank in p.value_classic":6045,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904031","Term":"positive regulation of cyclin-dependent protein kinase activity","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6046,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904238","Term":"pericyte cell differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6047,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904292","Term":"regulation of ERAD pathway","Annotated":24,"Significant":0,"Expected":1.45,"Rank in p.value_classic":6048,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904294","Term":"positive regulation of ERAD pathway","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":6049,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904321","Term":"response to forskolin","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6050,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904322","Term":"cellular response to forskolin","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6051,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904505","Term":"regulation of telomere maintenance in response to DNA damage","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":6052,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904507","Term":"positive regulation of telomere maintenance in response to DNA damage","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6053,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904748","Term":"regulation of apoptotic process involved in development","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6054,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904779","Term":"regulation of protein localization to centrosome","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6055,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904814","Term":"regulation of protein localization to chromosome, telomeric region","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":6056,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904816","Term":"positive regulation of protein localization to chromosome, telomeric region","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6057,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904851","Term":"positive regulation of establishment of protein localization to telomere","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6058,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904861","Term":"excitatory synapse assembly","Annotated":23,"Significant":0,"Expected":1.39,"Rank in p.value_classic":6059,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904867","Term":"protein localization to Cajal body","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6060,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904869","Term":"regulation of protein localization to Cajal body","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6061,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904871","Term":"positive regulation of protein localization to Cajal body","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6062,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904872","Term":"regulation of telomerase RNA localization to Cajal body","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":6063,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904874","Term":"positive regulation of telomerase RNA localization to Cajal body","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6064,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904889","Term":"regulation of excitatory synapse assembly","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6065,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904896","Term":"ESCRT complex disassembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6066,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904903","Term":"ESCRT III complex disassembly","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6067,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904948","Term":"midbrain dopaminergic neuron differentiation","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":6068,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1904996","Term":"positive regulation of leukocyte adhesion to vascular endothelial cell","Annotated":21,"Significant":0,"Expected":1.27,"Rank in p.value_classic":6069,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905038","Term":"regulation of membrane lipid metabolic process","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6070,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905048","Term":"regulation of metallopeptidase activity","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6071,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905063","Term":"regulation of vascular associated smooth muscle cell differentiation","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6072,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905144","Term":"response to acetylcholine","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":6073,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905145","Term":"cellular response to acetylcholine","Annotated":25,"Significant":0,"Expected":1.51,"Rank in p.value_classic":6074,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905168","Term":"positive regulation of double-strand break repair via homologous recombination","Annotated":34,"Significant":0,"Expected":2.05,"Rank in p.value_classic":6075,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905209","Term":"positive regulation of cardiocyte differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6076,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905314","Term":"semi-lunar valve development","Annotated":42,"Significant":0,"Expected":2.54,"Rank in p.value_classic":6077,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905456","Term":"regulation of lymphoid progenitor cell differentiation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6078,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905671","Term":"regulation of lysosome organization","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6079,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905709","Term":"negative regulation of membrane permeability","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":6080,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905874","Term":"regulation of postsynaptic density organization","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":6081,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905906","Term":"regulation of amyloid fibril formation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":6082,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1905907","Term":"negative regulation of amyloid fibril formation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6083,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1990173","Term":"protein localization to nucleoplasm","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":6084,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1990403","Term":"embryonic brain development","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6085,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:1990700","Term":"nucleolar chromatin organization","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6086,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000008","Term":"regulation of protein localization to cell surface","Annotated":37,"Significant":0,"Expected":2.23,"Rank in p.value_classic":6087,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000009","Term":"negative regulation of protein localization to cell surface","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6088,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000010","Term":"positive regulation of protein localization to cell surface","Annotated":17,"Significant":0,"Expected":1.03,"Rank in p.value_classic":6089,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000142","Term":"regulation of DNA-templated transcription initiation","Annotated":78,"Significant":0,"Expected":4.71,"Rank in p.value_classic":6090,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000144","Term":"positive regulation of DNA-templated transcription initiation","Annotated":66,"Significant":0,"Expected":3.99,"Rank in p.value_classic":6091,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000232","Term":"regulation of rRNA processing","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":6092,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000234","Term":"positive regulation of rRNA processing","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6093,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000288","Term":"positive regulation of myoblast proliferation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6094,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000291","Term":"regulation of myoblast proliferation","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6095,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000303","Term":"regulation of ceramide biosynthetic process","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6096,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000311","Term":"regulation of AMPA receptor activity","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6097,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000622","Term":"regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6098,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000629","Term":"negative regulation of miRNA metabolic process","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":6099,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000637","Term":"positive regulation of miRNA-mediated gene silencing","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6100,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000671","Term":"regulation of motor neuron apoptotic process","Annotated":13,"Significant":0,"Expected":0.79,"Rank in p.value_classic":6101,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000677","Term":"regulation of transcription regulatory region DNA binding","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":6102,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000679","Term":"positive regulation of transcription regulatory region DNA binding","Annotated":15,"Significant":0,"Expected":0.91,"Rank in p.value_classic":6103,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000739","Term":"regulation of mesenchymal stem cell differentiation","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6104,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000765","Term":"regulation of cytoplasmic translation","Annotated":32,"Significant":0,"Expected":1.93,"Rank in p.value_classic":6105,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000767","Term":"positive regulation of cytoplasmic translation","Annotated":14,"Significant":0,"Expected":0.85,"Rank in p.value_classic":6106,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000810","Term":"regulation of bicellular tight junction assembly","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":6107,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2000819","Term":"regulation of nucleotide-excision repair","Annotated":27,"Significant":0,"Expected":1.63,"Rank in p.value_classic":6108,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001014","Term":"regulation of skeletal muscle cell differentiation","Annotated":16,"Significant":0,"Expected":0.97,"Rank in p.value_classic":6109,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001044","Term":"regulation of integrin-mediated signaling pathway","Annotated":19,"Significant":0,"Expected":1.15,"Rank in p.value_classic":6110,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001046","Term":"positive regulation of integrin-mediated signaling pathway","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6111,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001135","Term":"regulation of endocytic recycling","Annotated":18,"Significant":0,"Expected":1.09,"Rank in p.value_classic":6112,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001138","Term":"regulation of phospholipid transport","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6113,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001140","Term":"positive regulation of phospholipid transport","Annotated":11,"Significant":0,"Expected":0.66,"Rank in p.value_classic":6114,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001241","Term":"positive regulation of extrinsic apoptotic signaling pathway in absence of ligand","Annotated":10,"Significant":0,"Expected":0.6,"Rank in p.value_classic":6115,"p.value_elim":1,"p.value_classic":1,"genes":""} {"GO.ID":"GO:2001256","Term":"regulation of store-operated calcium entry","Annotated":12,"Significant":0,"Expected":0.72,"Rank in p.value_classic":6116,"p.value_elim":1,"p.value_classic":1,"genes":""}