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{"category":"GO:0044419","over_represented_pvalue":1.07548e-38,"under_represented_pvalue":1,"numDEInCat":198,"numInCat":1291,"term":"biological process involved in interspecies interaction between 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{"category":"GO:0034097","over_represented_pvalue":5.80612e-22,"under_represented_pvalue":1,"numDEInCat":118,"numInCat":783,"term":"response to 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{"category":"GO:0006950","over_represented_pvalue":8.23949e-21,"under_represented_pvalue":1,"numDEInCat":302,"numInCat":3175,"term":"response to 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{"category":"GO:0009617","over_represented_pvalue":9.87417e-21,"under_represented_pvalue":1,"numDEInCat":86,"numInCat":485,"term":"response to 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{"category":"GO:0048584","over_represented_pvalue":6.92107e-19,"under_represented_pvalue":1,"numDEInCat":204,"numInCat":1906,"term":"positive regulation of response to 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{"category":"GO:0019884","over_represented_pvalue":1.18948e-17,"under_represented_pvalue":1,"numDEInCat":24,"numInCat":47,"term":"antigen processing and presentation of exogenous antigen","ontology":"BP","p.adj":4.62926e-15,"genes":"ENSG00000231389,ENSG00000204257,ENSG00000204267,ENSG00000242574,ENSG00000019582,ENSG00000204252,ENSG00000204287,ENSG00000223865,ENSG00000196126,ENSG00000204642,ENSG00000179344,ENSG00000198502,ENSG00000092010,ENSG00000204592,ENSG00000206503,ENSG00000232629,ENSG00000241106,ENSG00000196735,ENSG00000166710,ENSG00000163131,ENSG00000158477,ENSG00000158481,ENSG00000237541,ENSG00000135047","genesymbols":"B2M,CD1A,CD1C,CD74,CTSL,CTSS,HLA-A,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5,HLA-E,HLA-F,PSME1,TAP2"} {"category":"GO:0001775","over_represented_pvalue":1.36502e-17,"under_represented_pvalue":1,"numDEInCat":120,"numInCat":910,"term":"cell 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{"category":"GO:0002253","over_represented_pvalue":1.8568e-17,"under_represented_pvalue":1,"numDEInCat":76,"numInCat":445,"term":"activation of immune 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{"category":"GO:0032103","over_represented_pvalue":3.32194e-17,"under_represented_pvalue":1,"numDEInCat":84,"numInCat":529,"term":"positive regulation of response to external 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{"category":"GO:0042110","over_represented_pvalue":5.46375e-17,"under_represented_pvalue":1,"numDEInCat":78,"numInCat":473,"term":"T cell 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{"category":"GO:0051239","over_represented_pvalue":7.71726e-17,"under_represented_pvalue":1,"numDEInCat":231,"numInCat":2361,"term":"regulation of multicellular organismal 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{"category":"GO:0007159","over_represented_pvalue":4.54595e-15,"under_represented_pvalue":1,"numDEInCat":61,"numInCat":343,"term":"leukocyte cell-cell 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{"category":"GO:0002697","over_represented_pvalue":4.88284e-15,"under_represented_pvalue":1,"numDEInCat":57,"numInCat":306,"term":"regulation of immune effector 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{"category":"GO:0042221","over_represented_pvalue":1.4307e-14,"under_represented_pvalue":1,"numDEInCat":257,"numInCat":2842,"term":"response to 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{"category":"GO:0019886","over_represented_pvalue":1.47778e-14,"under_represented_pvalue":1,"numDEInCat":17,"numInCat":28,"term":"antigen processing and presentation of exogenous peptide antigen via MHC class II","ontology":"BP","p.adj":3.36228e-12,"genes":"ENSG00000231389,ENSG00000204257,ENSG00000242574,ENSG00000019582,ENSG00000204252,ENSG00000204287,ENSG00000223865,ENSG00000196126,ENSG00000179344,ENSG00000198502,ENSG00000232629,ENSG00000241106,ENSG00000196735,ENSG00000166710,ENSG00000163131,ENSG00000237541,ENSG00000135047","genesymbols":"B2M,CD74,CTSL,CTSS,HLA-DMA,HLA-DMB,HLA-DOA,HLA-DOB,HLA-DPA1,HLA-DPB1,HLA-DQA1,HLA-DQA1,HLA-DQB1,HLA-DQB2,HLA-DRA,HLA-DRB1,HLA-DRB5"} {"category":"GO:0051607","over_represented_pvalue":2.05026e-14,"under_represented_pvalue":1,"numDEInCat":51,"numInCat":262,"term":"defense response to 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{"category":"GO:0051240","over_represented_pvalue":1.51999e-13,"under_represented_pvalue":1,"numDEInCat":144,"numInCat":1338,"term":"positive regulation of multicellular organismal 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{"category":"GO:0080134","over_represented_pvalue":6.15354e-12,"under_represented_pvalue":1,"numDEInCat":127,"numInCat":1180,"term":"regulation of response to 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{"category":"GO:0002833","over_represented_pvalue":8.14843e-12,"under_represented_pvalue":1,"numDEInCat":53,"numInCat":324,"term":"positive regulation of response to biotic 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{"category":"GO:0051251","over_represented_pvalue":8.7748e-12,"under_represented_pvalue":1,"numDEInCat":49,"numInCat":286,"term":"positive regulation of lymphocyte 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response","ontology":"BP","p.adj":3.83653e-08,"genes":"ENSG00000242574,ENSG00000183734,ENSG00000019582,ENSG00000204287,ENSG00000096996,ENSG00000073861,ENSG00000196126,ENSG00000204642,ENSG00000079385,ENSG00000123609,ENSG00000198829,ENSG00000168329,ENSG00000127951,ENSG00000104312,ENSG00000018280,ENSG00000169508,ENSG00000197272,ENSG00000068079,ENSG00000178562,ENSG00000090339,ENSG00000120337,ENSG00000121594,ENSG00000162739,ENSG00000189171,ENSG00000163874,ENSG00000105639,ENSG00000174371,ENSG00000117090,ENSG00000239998,ENSG00000064932,ENSG00000135636,ENSG00000065427,ENSG00000158481,ENSG00000171522,ENSG00000104856,ENSG00000113916,ENSG00000254087,ENSG00000198719,ENSG00000076248,ENSG00000119508,ENSG00000041880,ENSG00000137265","genesymbols":"ASCL2,BCL6,CD1C,CD28,CD74,CD80,CEACAM1,CX3CR1,DLL1,DYSF,EXO1,FGL2,GPR183,HLA-DMB,HLA-DRA,HLA-DRB1,HLA-F,ICAM1,IFI35,IL12RB1,IL27,IRF4,JAK3,KARS1,LILRA2,LYN,NMI,NR4A3,PARP3,PTGER4,RELB,RIPK2,S100A13,SBNO2,SLAMF1,SLAMF6,SLC11A1,SUCNR1,TBX21,TNFSF18,UNG,ZC3H12A"} {"category":"GO:0051250","over_represented_pvalue":3.31005e-10,"under_represented_pvalue":1,"numDEInCat":29,"numInCat":129,"term":"negative regulation of lymphocyte activation","ontology":"BP","p.adj":4.04565e-08,"genes":"ENSG00000125347,ENSG00000131203,ENSG00000183734,ENSG00000019582,ENSG00000185338,ENSG00000120217,ENSG00000197646,ENSG00000089692,ENSG00000073861,ENSG00000196126,ENSG00000204592,ENSG00000153064,ENSG00000163599,ENSG00000127951,ENSG00000104951,ENSG00000121594,ENSG00000064201,ENSG00000146072,ENSG00000163874,ENSG00000105639,ENSG00000104760,ENSG00000124508,ENSG00000204632,ENSG00000113916,ENSG00000254087,ENSG00000157873,ENSG00000041880,ENSG00000153208,ENSG00000092445","genesymbols":"ASCL2,BANK1,BCL6,BTN2A2,CD274,CD74,CD80,CTLA4,FGL1,FGL2,HLA-DRB1,HLA-E,HLA-G,IDO1,IL4I1,IRF1,JAK3,LAG3,LYN,MERTK,PARP3,PDCD1LG2,SOCS1,TBX21,TNFRSF14,TNFRSF21,TSPAN32,TYRO3,ZC3H12A"} {"category":"GO:0050789","over_represented_pvalue":4.06853e-10,"under_represented_pvalue":1,"numDEInCat":600,"numInCat":8800,"term":"regulation of biological 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