Package: mitoClone2 Type: Package Title: Clonal Population Identification in Single-Cell RNA-Seq Data using Mitochondrial and Somatic Mutations LinkingTo: Rhtslib (>= 1.13.1) Version: 1.19.0 Authors@R: c( person(given = "Benjamin", family = "Story", role = c("aut", "cre"), email = "story.benjamin@gmail.com"), person(given = "Lars", family = "Velten", role = "aut"), person(given = "Gregor", family = "Mönke", role = "aut") ) Description: This package primarily identifies variants in mitochondrial genomes from BAM alignment files. It filters these variants to remove RNA editing events then estimates their evolutionary relationship (i.e. their phylogenetic tree) and groups single cells into clones. It also visualizes the mutations and providing additional genomic context. License: GPL-3 VignetteBuilder: knitr Encoding: UTF-8 LazyData: false biocViews: Annotation, DataImport, Genetics, SNP, Software, SingleCell, Alignment Imports: reshape2, GenomicRanges, pheatmap, deepSNV, grDevices, Matrix, graphics, stats, utils, S4Vectors, Rhtslib, parallel, methods, ggplot2 Suggests: knitr, rmarkdown, Biostrings, testthat RoxygenNote: 7.1.0 SystemRequirements: GNU make, PhISCS (optional) Depends: R (>= 4.4.0) NeedsCompilation: yes URL: https://github.com/benstory/mitoClone2 Bugreports: https://github.com/benstory/mitoClone2/issues Config/pak/sysreqs: make libbz2-dev libicu-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:56:35 UTC RemoteUrl: https://github.com/bioc/mitoClone2 RemoteRef: HEAD RemoteSha: 179a14fa42115822941b074ad9be70c089915527 Packaged: 2026-07-03 16:57:34 UTC; root Author: Benjamin Story [aut, cre], Lars Velten [aut], Gregor Mönke [aut] Maintainer: Benjamin Story