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# CITATION file created with {cffr} R package
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cff-version: 1.2.0
message: 'To cite package "mitch" in publications use:'
type: software
license: CC-BY-SA-4.0
title: 'mitch: Multi-Contrast Gene Set Enrichment Analysis'
version: 1.17.2
doi: 10.1186/s12864-020-06856-9
identifiers:
- type: doi
  value: 10.32614/CRAN.package.mitch
abstract: mitch is an R package for multi-contrast enrichment analysis. At it’s heart,
  it uses a rank-MANOVA based statistical approach to detect sets of genes that exhibit
  enrichment in the multidimensional space as compared to the background. The rank-MANOVA
  concept dates to work by Cox and Mann (https://doi.org/10.1186/1471-2105-13-S16-S12).
  mitch is useful for pathway analysis of profiling studies with one, two or more
  contrasts, or in studies with multiple omics profiling, for example proteomic, transcriptomic,
  epigenomic analysis of the same samples. mitch is perfectly suited for pathway level
  differential analysis of scRNA-seq data. We have an established routine for pathway
  enrichment of Infinium Methylation Array data (see vignette). The main strengths
  of mitch are that it can import datasets easily from many upstream tools and has
  advanced plotting features to visualise these enrichments.
authors:
- family-names: Ziemann
  given-names: Mark
  email: mark.ziemann@gmail.com
  orcid: https://orcid.org/0000-0002-7688-6974
- family-names: Kaspi
  given-names: Antony
preferred-citation:
  type: article
  title: 'mitch: multi-contrast pathway enrichment for multi-omics and single-cell
    profiling data'
  authors:
  - family-names: Kaspi
    given-names: Antony
  - family-names: Ziemann
    given-names: Mark
    email: mark.ziemann@gmail.com
    orcid: https://orcid.org/0000-0002-7688-6974
  year: '2020'
  journal: BMC Genomics
  doi: 10.1186/s12864-020-06856-9
  volume: '21'
  issue: '1'
  start: '447'
repository: https://bioc.r-universe.dev
repository-code: https://github.com/markziemann/mitch
commit: ce7121b4011bc78e09592039829fbcdca314e3c6
url: https://github.com/markziemann/mitch
contact:
- family-names: Ziemann
  given-names: Mark
  email: mark.ziemann@gmail.com
  orcid: https://orcid.org/0000-0002-7688-6974