Package: mist
Title: Differential Methylation Analysis for scDNAm Data
Version: 1.5.0
Depends: R (>= 4.5.0)
Authors@R: 
    person("Daoyu", "Duan", , "dxd429@case.edu", role = c("aut", "cre"),
           comment = c(ORCID = "0000-0002-3147-2006"))
Description: mist (Methylation Inference for Single-cell along
        Trajectory) is a hierarchical Bayesian framework for modeling
        DNA methylation trajectories and performing differential
        methylation (DM) analysis in single-cell DNA methylation
        (scDNAm) data. It estimates developmental-stage-specific
        variations, identifies genomic features with drastic changes
        along pseudotime, and, for two phenotypic groups, detects
        features with distinct temporal methylation patterns. mist uses
        Gibbs sampling to estimate parameters for temporal changes and
        stage-specific variations.
License: MIT + file LICENSE
Encoding: UTF-8
URL: https://https://github.com/dxd429/mist
BugReports: https://https://github.com/dxd429/mist/issues
biocViews: Epigenetics, DifferentialMethylation, DNAMethylation,
        SingleCell, Software
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Imports: BiocParallel, MCMCpack, Matrix, S4Vectors, methods,
        rtracklayer, car, mvtnorm, SummarizedExperiment,
        SingleCellExperiment, BiocGenerics, stats, rlang
Suggests: knitr, rmarkdown, RUnit, ggplot2, BiocStyle
VignetteBuilder: knitr
Config/pak/sysreqs: cmake make libbz2-dev libicu-dev liblzma-dev
        libxml2-dev libssl-dev xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 13:04:10 UTC
RemoteUrl: https://github.com/bioc/mist
RemoteRef: HEAD
RemoteSha: 8e21d2e7c03bb8e11bdbf8fa6cd3b108eaf0d8b9
NeedsCompilation: no
Packaged: 2026-07-04 23:22:19 UTC; root
Author: Daoyu Duan [aut, cre] (ORCID: <https://orcid.org/0000-0002-3147-2006>)
Maintainer: Daoyu Duan <dxd429@case.edu>