Package: methylSig
Title: MethylSig: Differential Methylation Testing for WGBS and RRBS
        Data
Version: 1.25.0
Date: 2025-07-28
Authors@R: 
    c(person(given = "Yongseok",
             family = "Park",
             role = "aut",
             email = "yongpark@pitt.edu"),
      person(given = "Raymond G.",
             family = "Cavalcante",
             role = c("aut", "cre"),
             email = "rcavalca@umich.edu"))
Description: MethylSig is a package for testing for differentially
        methylated cytosines (DMCs) or regions (DMRs) in whole-genome
        bisulfite sequencing (WGBS) or reduced representation bisulfite
        sequencing (RRBS) experiments.  MethylSig uses a beta binomial
        model to test for significant differences between groups of
        samples. Several options exist for either site-specific or
        sliding window tests, and variance estimation.
Depends: R (>= 3.6)
Imports: bsseq, DelayedArray, DelayedMatrixStats, DSS, IRanges,
        Seqinfo, GenomicRanges, methods, parallel, stats, S4Vectors
Suggests: BiocStyle, bsseqData, knitr, rmarkdown, testthat (>= 2.1.0),
        covr
License: GPL-3
BugReports: https://github.com/sartorlab/methylSig/issues
biocViews: DNAMethylation, DifferentialMethylation, Epigenetics,
        Regression, MethylSeq
Encoding: UTF-8
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 7.1.0
Config/pak/sysreqs: make libbz2-dev liblzma-dev libxml2-dev libssl-dev
        xz-utils zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:52:33 UTC
RemoteUrl: https://github.com/bioc/methylSig
RemoteRef: HEAD
RemoteSha: 3cf80514e4f196e89208c2bd9353547324dc807d
NeedsCompilation: no
Packaged: 2026-07-04 13:22:41 UTC; root
Author: Yongseok Park [aut],
  Raymond G. Cavalcante [aut, cre]
Maintainer: Raymond G. Cavalcante <rcavalca@umich.edu>