Package: magrene Title: Motif Analysis In Gene Regulatory Networks Version: 1.15.0 Date: 2022-01-21 Authors@R: c( person(given = "Fabrício", family = "Almeida-Silva", role = c("aut", "cre"), email = "fabricio_almeidasilva@hotmail.com", comment = c(ORCID = "0000-0002-5314-2964")), person(given = "Yves", family = "Van de Peer", role = "aut", comment = c(ORCID = "0000-0003-4327-3730")) ) Description: magrene allows the identification and analysis of graph motifs in (duplicated) gene regulatory networks (GRNs), including lambda, V, PPI V, delta, and bifan motifs. GRNs can be tested for motif enrichment by comparing motif frequencies to a null distribution generated from degree-preserving simulated GRNs. Motif frequencies can be analyzed in the context of gene duplications to explore the impact of small-scale and whole-genome duplications on gene regulatory networks. Finally, users can calculate interaction similarity for gene pairs based on the Sorensen-Dice similarity index. License: GPL-3 URL: https://github.com/almeidasilvaf/magrene BugReports: https://support.bioconductor.org/t/magrene biocViews: Software, MotifDiscovery, NetworkEnrichment, SystemsBiology, GraphAndNetwork Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.0 Imports: utils, stats, BiocParallel Suggests: BiocStyle, covr, knitr, rmarkdown, ggplot2, sessioninfo, testthat (>= 3.0.0) Config/testthat/edition: 3 VignetteBuilder: knitr Depends: R (>= 4.2.0) LazyData: false Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:59:07 UTC RemoteUrl: https://github.com/bioc/magrene RemoteRef: HEAD RemoteSha: b2761b420710edfe5cee2a0f1eb543ba3efc3803 NeedsCompilation: no Packaged: 2026-07-15 05:24:20 UTC; root Author: Fabrício Almeida-Silva [aut, cre] (ORCID: ), Yves Van de Peer [aut] (ORCID: ) Maintainer: Fabrício Almeida-Silva