Changes in version 1.99.6                        

    o   some minor fixes to RLE section

    o   minor text edits as suggested by James McDonald at F1000

    o   modified to code chunk that checks for latex compilation

                       Changes in version 1.99.2                        

    o   changed installation instructions to BiocManager

                       Changes in version 0.99.0                        

    o   new submission to  Bioc in June 18