Package: les Type: Package Title: Identifying Differential Effects in Tiling Microarray Data Version: 1.63.0 Author: Julian Gehring, Clemens Kreutz, Jens Timmer Maintainer: Julian Gehring Imports: boot, gplots, RColorBrewer Depends: R (>= 2.13.2), methods, graphics, fdrtool Suggests: Biobase, limma Enhances: parallel Description: The 'les' package estimates Loci of Enhanced Significance (LES) in tiling microarray data. These are regions of regulation such as found in differential transcription, CHiP-chip, or DNA modification analysis. The package provides a universal framework suitable for identifying differential effects in tiling microarray data sets, and is independent of the underlying statistics at the level of single probes. License: GPL-3 LazyLoad: yes biocViews: Microarray, DifferentialExpression, ChIPchip, DNAMethylation, Transcription Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:34:50 UTC RemoteUrl: https://github.com/bioc/les RemoteRef: HEAD RemoteSha: 6a07807bd6d408a55473c5dd66ce496b985176c0 NeedsCompilation: no Packaged: 2026-06-23 06:32:21 UTC; root