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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "lemur" in publications use:'
type: software
license: MIT
title: 'lemur: Latent Embedding Multivariate Regression'
version: 1.3.2
doi: 10.1101/2023.03.06.531268
abstract: Fit a latent embedding multivariate regression (LEMUR) model to multi-condition
  single-cell data. The model provides a parametric description of single-cell data
  measured with treatment vs. control or more complex experimental designs. The parametric
  model is used to (1) align conditions, (2) predict log fold changes between conditions
  for all cells, and (3) identify cell neighborhoods with consistent log fold changes.
  For those neighborhoods, a pseudobulked differential expression test is conducted
  to assess which genes are significantly changed.
authors:
- family-names: Ahlmann-Eltze
  given-names: Constantin
  email: artjom31415@googlemail.com
  orcid: https://orcid.org/0000-0002-3762-068X
preferred-citation:
  type: article
  title: Analysis of multi-condition single-cell data with latent embedding multivariate
    regression
  authors:
  - family-names: Ahlmann-Eltze
    given-names: Constantin
    email: artjom31415@googlemail.com
    orcid: https://orcid.org/0000-0002-3762-068X
  - family-names: Huber
    given-names: Wolfgang
  journal: bioRxiv
  year: '2023'
  doi: 10.1101/2023.03.06.531268
repository: https://bioc.r-universe.dev
repository-code: https://github.com/const-ae/lemur
url: https://github.com/const-ae/lemur
contact:
- family-names: Ahlmann-Eltze
  given-names: Constantin
  email: artjom31415@googlemail.com
  orcid: https://orcid.org/0000-0002-3762-068X