Package: katdetectr Title: Detection, Characterization and Visualization of Kataegis in Sequencing Data Version: 1.15.0 Date: 2023-02-14 Authors@R: c( person("Daan", "Hazelaar", , "daanhazelaar@gmail.com", role = c("aut", "cre"), comment = c(ORCID = "0000-0002-7513-6813")), person("Job", "van Riet", , "j.vanriet@erasmusmc.nl", role = "aut", comment = c(ORCID = "0000-0001-7767-7923")), person("Harmen", "van de Werken", , "h.vandewerken@erasmusmc.nl", role = "ths", comment = c(ORCID = "0000-0002-9794-1477")) ) Description: Kataegis refers to the occurrence of regional hypermutation and is a phenomenon observed in a wide range of malignancies. Using changepoint detection katdetectr aims to identify putative kataegis foci from common data-formats housing genomic variants. Katdetectr has shown to be a robust package for the detection, characterization and visualization of kataegis. License: GPL-3 + file LICENSE URL: https://doi.org/doi:10.18129/B9.bioc.katdetectr BugReports: https://github.com/ErasmusMC-CCBC/katdetectr/issues Depends: R (>= 4.2) Imports: Biobase (>= 2.54.0), BiocParallel (>= 1.26.2), BSgenome (>= 1.62.0), BSgenome.Hsapiens.UCSC.hg19 (>= 1.4.3), BSgenome.Hsapiens.UCSC.hg38 (>= 1.4.4), changepoint (>= 2.2.3), changepoint.np (>= 1.0.3), checkmate (>= 2.0.0), dplyr (>= 1.0.8), GenomeInfoDb (>= 1.28.4), GenomicRanges (>= 1.44.0), ggplot2 (>= 3.3.5), ggtext (>= 0.1.1), IRanges (>= 2.26.0), maftools (>= 2.10.5), methods (>= 4.1.3), plyranges (>= 1.17.0), Rdpack (>= 2.3.1), rlang (>= 1.0.2), S4Vectors (>= 0.30.2), scales (>= 1.2.0), tibble (>= 3.1.6), tidyr (>= 1.2.0), tools, utils, VariantAnnotation (>= 1.38.0) Suggests: BiocStyle (>= 2.26.0), knitr (>= 1.37), rmarkdown (>= 2.13), stats, testthat (>= 3.0.0) VignetteBuilder: knitr RdMacros: Rdpack biocViews: WholeGenome, Software, SNP, Sequencing, Classification, VariantAnnotation Config/testthat/edition: 3 Encoding: UTF-8 Roxygen: list(markdown = TRUE) RoxygenNote: 7.2.3 Config/pak/sysreqs: make libbz2-dev libicu-dev libjpeg-dev liblzma-dev libpng-dev libxml2-dev libssl-dev xz-utils zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:58:33 UTC RemoteUrl: https://github.com/bioc/katdetectr RemoteRef: HEAD RemoteSha: b2135a5276bec5f2b5ab607efbb14c97578c47b3 NeedsCompilation: no Packaged: 2026-06-10 06:51:49 UTC; root Author: Daan Hazelaar [aut, cre] (ORCID: ), Job van Riet [aut] (ORCID: ), Harmen van de Werken [ths] (ORCID: ) Maintainer: Daan Hazelaar