Changes in version 1.1.1 o Introduction of the problematicUnevenDistribution flag in the core islify function. Changes in version 0.99.8-10 o Small changes to bugs to various functions Changes in version 0.99.7 o Major update, adding under-the-hood functionality in the islify function o The output of islify can now account for the area covered by nuclei. o A median chunk filter is now included for images wider or longer than 1000 pixels, making it possible to reduce the influence of non-representative large areas of low but above background intensity on the score. o The zprime function, originally publised in the imageHTS package has been resurrected. Changes in version 0.99.4-6 (2025-02-05) o DS_Store and .Rproj removed from git. Changes in version 0.99.3 (2025-02-04) o Adding new email address to Bioc-Devel mailing list. o getQuantileIntensities bug removed. Changes in version 0.99.2 (2025-01-12) o A more elaborate introduction to the vinjette is added. Changes in version 0.99.1 (2025-01-10) o This is the first time the NEWS file is present. o For all previous changes, and those are hundreds, see the git push messages.