Package: immLynx Title: Linking Advanced TCR Python Pipelines and Hugging Face Models in R Version: 1.1.3 Authors@R: c( person(given = "Nick", family = "Borcherding", role = c("aut", "cre"), email = "ncborch@gmail.com", comment = c(ORCID = "0000-0003-1427-6342"))) Description: A comprehensive toolkit that bridges popular Python-based immune repertoire analysis tools and Hugging Face protein language models into the R environment. Provides unified interfaces for TCR distance calculations (tcrdist3), sequence generation probability (OLGA), selection inference (soNNia), clustering (clusTCR), protein embeddings (ESM-2), metaclone discovery (metaclonotypist), clonal expansion prediction from gene expression (scXpand), near-neighbor search by symmetric deletion lookup (pyrepseq), and deep generative featurization (DeepTCR). Fully compatible with the scRepertoire and immApex ecosystem for single-cell immune repertoire analysis. License: MIT + file LICENSE Encoding: UTF-8 biocViews: Software, ImmunoOncology, SingleCell, Classification, Annotation, Sequencing, MotifAnnotation, Clustering, DimensionReduction, GeneExpression Depends: R (>= 4.5.0) Imports: basilisk (>= 1.8.0), reticulate (>= 1.24), immApex, methods, S4Vectors, SingleCellExperiment, stats, SummarizedExperiment, tools, utils, zellkonverter Suggests: AnnotationDbi, BiocStyle, data.table, ggplot2, knitr, markdown, Matrix, org.Hs.eg.db, rmarkdown, scater, scran, scRepertoire, Seurat, spelling, testthat (>= 3.0.0), withr VignetteBuilder: knitr Language: en-US URL: https://github.com/BorchLab/immLynx/ BugReports: https://github.com/BorchLab/immLynx/issues StagedInstall: no Config/testthat/edition: 3 Config/roxygen2/version: 8.0.0 Config/pak/sysreqs: libicu-dev libpng-dev libxml2-dev libssl-dev python3 zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-10-27 12:29:31 UTC RemoteUrl: https://github.com/bioc/immLynx RemoteRef: HEAD RemoteSha: 0b5b5b44ee5664e888f456b82844767df7930b72 NeedsCompilation: no Packaged: 2026-10-27 14:54:05 UTC; root Author: Nick Borcherding [aut, cre] (ORCID: ) Maintainer: Nick Borcherding