humanHippocampus2024

Welcome to the humanHippocampus2024 package!

This package helps to access the spatially-resolved transcriptomics (SRT) and single-nucleus RNA-sequencing (snRNA-seq) data from adjacent tissue sections of the anterior human hippocampus across ten adult neurotypical donors generated by Lieber Institute for Brain Development (LIBD) researchers and collaborators.

Installation

Please use R (version "4.4") and Bioconductor 3.20 then enter:

if (!requireNamespace("BiocManager", quietly = TRUE)) {
    install.packages("BiocManager")
}

BiocManager::install("humanHippocampus2024")

## Check that you have a valid Bioconductor installation
BiocManager::valid()

The development version can be installed from GitHub:

install.packages("remotes")
remotes::install_github("christinehou11/humanHippocampus2024")

Please read Introduction to humanHippocampus2024 for detailed descriptions and tutorials.

Data Specifics

• spe.rda: (spe object) SpatialExperiment with spatially-resolved transcriptomics (SRT) from adjacent tissue sections of the anterior human hippocampus across ten adult neurotypical donors usng 10x Genomics Visium, generated at the Lieber Institute for Brain Development (LIBD)

• sce.rda: (sce object) SingleCellExperiment with single-nucleus RNA-sequencing (snRNA-seq) from adjacent tissue sections of the anterior human hippocampus across ten adult neurotypical donors usng 10x Genomics Visium, generated at the Lieber Institute for Brain Development (LIBD)

Code of Conduct

Please note that the humanHippocampus2024 project is released with a Contributor Code of Conduct. By contributing to this project, you agree to abide by its terms.