Package: hipathia Title: HiPathia: High-throughput Pathway Analysis Version: 3.13.0 Authors@R: c(person("Marta R.", "Hidalgo", email = "marta.hidalgo@outlook.es", role = c("aut", "cre")), person("José", "Carbonell-Caballero", role = c("ctb")), person("Francisco", "Salavert", role = c("ctb")), person("Alicia", "Amadoz", role = c("ctb")), person("Çankut", "Cubuk", role = c("ctb")), person("Joaquin", "Dopazo", role = c("ctb"))) Description: Hipathia is a method for the computation of signal transduction along signaling pathways from transcriptomic data. The method is based on an iterative algorithm which is able to compute the signal intensity passing through the nodes of a network by taking into account the level of expression of each gene and the intensity of the signal arriving to it. It also provides a new approach to functional analysis allowing to compute the signal arriving to the functions annotated to each pathway. Depends: R (>= 4.1), igraph (>= 1.0.1), zen4R(>= 0.10.4), MultiAssayExperiment(>= 1.4.9), SummarizedExperiment(>= 1.8.1) License: GPL-2 Encoding: UTF-8 Imports: coin, stats, limma, grDevices, utils, graphics, preprocessCore, servr, DelayedArray, matrixStats, methods, S4Vectors, ggplot2, ggpubr, dplyr, tibble, visNetwork, reshape2, MetBrewer RoxygenNote: 7.3.3 Suggests: BiocStyle, knitr, rmarkdown, testthat VignetteBuilder: knitr biocViews: Pathways, GraphAndNetwork, GeneExpression, GeneSignaling, GO LazyData: true Config/pak/sysreqs: cmake libglpk-dev make libicu-dev libsecret-1-dev libuv1-dev libxml2-dev libssl-dev zlib1g-dev Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:47:49 UTC RemoteUrl: https://github.com/bioc/hipathia RemoteRef: HEAD RemoteSha: 88814b548e2b16ce6cb4af96cc9a173e2e1eb257 NeedsCompilation: no Packaged: 2026-06-19 06:53:57 UTC; root Author: Marta R. Hidalgo [aut, cre], José Carbonell-Caballero [ctb], Francisco Salavert [ctb], Alicia Amadoz [ctb], Çankut Cubuk [ctb], Joaquin Dopazo [ctb] Maintainer: Marta R. Hidalgo