Package: hierinf Type: Package Title: Hierarchical Inference Version: 1.31.0 Authors@R: c(person("Claude", "Renaux", role = c("aut", "cre"), email = "renaux@stat.math.ethz.ch"), person("Laura", "Buzdugan", role = c("aut")), person("Markus", "Kalisch", role = c("aut")), person("Peter", "Bühlmann", role = c("aut"))) Description: Tools to perform hierarchical inference for one or multiple studies / data sets based on high-dimensional multivariate (generalised) linear models. A possible application is to perform hierarchical inference for GWA studies to find significant groups or single SNPs (if the signal is strong) in a data-driven and automated procedure. The method is based on an efficient hierarchical multiple testing correction and controls the FWER. The functions can easily be run in parallel. License: GPL-3 | file LICENSE Encoding: UTF-8 LazyData: yes Depends: R (>= 3.6.0) Imports: fmsb, glmnet, methods, parallel, stats Suggests: knitr, MASS, testthat biocViews: Clustering, GenomeWideAssociation, LinkageDisequilibrium, Regression, SNP VignetteBuilder: knitr RoxygenNote: 6.1.1 Repository: https://bioc.r-universe.dev Date/Publication: 2026-04-28 12:48:26 UTC RemoteUrl: https://github.com/bioc/hierinf RemoteRef: HEAD RemoteSha: e9732418bc9000ad84a597b8df92c839970ed302 NeedsCompilation: no Packaged: 2026-07-03 20:14:46 UTC; root Author: Claude Renaux [aut, cre], Laura Buzdugan [aut], Markus Kalisch [aut], Peter Bühlmann [aut] Maintainer: Claude Renaux