# --------------------------------------------
# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
# --------------------------------------------
 
cff-version: 1.2.0
message: 'To cite package "gscreend" in publications use:'
type: software
license: GPL-3.0-only
title: 'gscreend: Analysis of pooled genetic screens'
version: 1.19.0
doi: 10.1186/s13059-020-1939-1
abstract: Package for the analysis of pooled genetic screens (e.g. CRISPR-KO). The
  analysis of such screens is based on the comparison of gRNA abundances before and
  after a cell proliferation phase. The gscreend packages takes gRNA counts as input
  and allows detection of genes whose knockout decreases or increases cell proliferation.
authors:
- family-names: Imkeller
  given-names: Katharina
  email: k.imkeller@dkfz.de
- family-names: Huber
  given-names: Wolfgang
  email: wolfgang.huber@embl.de
preferred-citation:
  type: article
  title: 'gscreend: modelling asymmetric count ratios in CRISPR screens to decrease
    experiment size and improve phenotype detection'
  authors:
  - family-names: Imkeller
    given-names: Katharina
    email: k.imkeller@dkfz.de
  - family-names: Ambrosi
    given-names: Giulia
  - family-names: Boutros
    given-names: Michael
  - family-names: Huber
    given-names: Wolfgang
    email: wolfgang.huber@embl.de
  year: '2020'
  journal: Genome Biology
  doi: 10.1186/s13059-020-1939-1
  volume: '21'
  issue: '53'
repository: https://bioc.r-universe.dev
repository-code: https://github.com/imkeller/gscreend
url: https://github.com/imkeller/gscreend
contact:
- family-names: Imkeller
  given-names: Katharina
  email: k.imkeller@dkfz.de