Package: gscreend
Type: Package
Title: Analysis of pooled genetic screens
Version: 1.27.0
Authors@R: c(
    person("Katharina", "Imkeller", email = "k.imkeller@dkfz.de", role = c("cre", "aut")),
    person("Wolfgang", "Huber", email = "wolfgang.huber@embl.de", role = "aut"))
Description: Package for the analysis of pooled genetic screens (e.g.
        CRISPR-KO). The analysis of such screens is based on the
        comparison of gRNA abundances before and after a cell
        proliferation phase. The gscreend packages takes gRNA counts as
        input and allows detection of genes whose knockout decreases or
        increases cell proliferation.
License: GPL-3
Encoding: UTF-8
Depends: R (>= 3.6)
Imports: SummarizedExperiment, nloptr, fGarch, methods, BiocParallel,
        graphics
Suggests: knitr, testthat, rmarkdown, BiocStyle
VignetteBuilder: knitr
RoxygenNote: 7.2.3
biocViews: Software, StatisticalMethod, PooledScreens, CRISPR
URL: https://github.com/imkeller/gscreend
BugReports: https://github.com/imkeller/gscreend/issues
Config/pak/sysreqs: cmake zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:51:08 UTC
RemoteUrl: https://github.com/bioc/gscreend
RemoteRef: HEAD
RemoteSha: b8621dfc5a485a070817ca8419ec6bfe9cf6958f
NeedsCompilation: no
Packaged: 2026-07-03 15:50:50 UTC; root
Author: Katharina Imkeller [cre, aut],
  Wolfgang Huber [aut]
Maintainer: Katharina Imkeller <k.imkeller@dkfz.de>