Changes in version 1.57.1 o Updated all pathway data. Changes in version 1.55.2 o Reinstated clipper support. Changes in version 1.55.1 o Automatic cleanup of stale pathway data. o Updated all pathway data. Changes in version 1.53.1 o Updated all pathway data. Changes in version 1.51.1 o Updated all pathway data. Changes in version 1.49.1 o Updated all pathway data. Changes in version 1.47.1 o Removed Clipper support. o Updated all pathway data. Changes in version 1.45.1 o Updated all pathway data. Changes in version 1.43.2 o Updated all pathway data. Changes in version 1.41.2 o Updated all pathway data. Changes in version 1.39.3 o Updated all pathway data. Changes in version 1.37.1 o Removed Biocarta and NCI pathways. o Added WikiPathways pathways. o Updated all pathway data. Changes in version 1.35.2 o Updated all pathway data. Changes in version 1.33.1 o Updated all pathway data. Changes in version 1.31.1 o Updated all pathway data. o Removed HumanCyc pathways (database now requires subscription). Changes in version 1.29.3 o Updated all pathway data. Changes in version 1.27.6 o Updated all pathway data. o Added PathBank database. Changes in version 1.27.2 o Vignette describing mixed analysis with genes and metabolites. Changes in version 1.25.9 o Updated all pathway data. Changes in version 1.25.7 o cytoscapePlot returns an handle to the exported graph. Changes in version 1.25.6 o Parallel versions of clipper and topologyGSA methods. Changes in version 1.25.3 o Faster conversion of identifiers. Changes in version 1.25.2 o Documentation fixes. o Removed deprecated objects biocarta, humancyc, kegg, nci, panther, reactome. Changes in version 1.25.1 o Export the pathwayURL function. Changes in version 1.23.7 o Provide the URL of each pathway in its original database. o New vignette describing pathway analysis of metabolic activities. Changes in version 1.23.6 o Removed DEGraph support. Changes in version 1.23.5 o runClipper gains an option to set the seed for random number generation. Changes in version 1.23.3 o Metabolites in pathways. o Multiple views of each pathway: proteins only, metabolites only or both. o New databases: SMPDB and PharmGKB. o Removed support for RCytoscape (by default, use RCy3). o Conversion of metabolite identifiers. o Faster conversion of idenfiers on multicore systems. Changes in version 1.21.1 o Updated all pathway data. Changes in version 1.19.3 o Updated all pathway data. Changes in version 1.17.6 o Added celegans pathways from KEGG. Changes in version 1.17.5 o Updated all pathway data. Changes in version 1.17.4 o Cytoscape 3 support. Changes in version 1.17.3 o Added the buildPathway function. Changes in version 1.15.3 o Updated all pathway data. o More descriptive edge types. o Use the package "rappdirs" to select a directory for cached files. o Updated all pathway data. o More descriptive edge types. o Use the package "rappdirs" to select a directory for cached files. Changes in version 1.13.2 o Pathways for multiple species: see pathwayDatabases() output. o Native pathway IDs. o Removed SPIKE database. o Deprecated objects: biocarta, humancyc, kegg, nci, panther, reactome. o Deprecated functions: runClipperMulti, runDEGraphMulti, runTopologyGSAMulti. Changes in version 1.11.4 o Updated Biocarta, KEGG, NCI, HumanCyc, Panther and Reactome data. Changes in version 1.9.4 o Updated Biocarta, KEGG, NCI and Reactome data. o New databases: HumanCyc and Panther.