Package 'goTools'

Title: Functions for Gene Ontology database
Description: Wraper functions for description/comparison of oligo ID list using Gene Ontology database
Authors: Yee Hwa (Jean) Yang <[email protected]>, Agnes Paquet <[email protected]>
Maintainer: Agnes Paquet <[email protected]>
License: GPL-2
Version: 1.79.0
Built: 2024-10-01 05:09:12 UTC
Source: https://github.com/bioc/goTools

Help Index


Reference GO nodes list.

Description

The function EndNodeList builds the default end node list used in ontoCompare. CustomEndNodeList helps you build a list of children nodes starting from a GO id of interest.

Usage

EndNodeList()
CustomEndNodeList(id,rank=1)

Arguments

id

Valid GO id: "GO:XXXXXXX".

rank

Number of levels of children of the GO DAG under id you want to add to your nodes list.

Value

EndNodeList returns a vector of all GO ids 1 level below MF("GO:0003674"), BP("GO:0008150") and CC("GO:0005575"). MF, BP and CC nodes are included. CustomEndNodeList returns a vector of all GO ids children of id, rank levels below it.

Author(s)

Yee Hwa (Jean) Yang, Agnes Paquet

See Also

ontoCompare

Examples

## Examples use the probeID dataset. For description type ? probeID.
## library(GO.db)
## EndNodeList()
## MFendnode <- CustomEndNodeList("GO:0003674", rank=2)

## Example (not run)
## data(probeID)
## ontoCompare(affylist, probeType="hgu133a", endnode=MFendnode, goType="MF")

Wrapper functions

Description

This functions will allow you to describe and compare sets of oligo ids using Gene Ontology database

Usage

ontoCompare(genelist,probeType=c("GO","hgu133a"),
goType="All", endnode, method=c("TGenes", "TIDS", "none"), plot=FALSE,
...)

ontoPlot(objM, names.arg=NULL,beside=TRUE, las=2,legend.text=TRUE, ...)

Arguments

genelist

list of list of valid probe ids.

method

method used to evaluate the percentage of oligos for each end-node. 'TGenes' = for each end node, return the number of direct children found / total number of probe ids. (default). This includes oligos which do not have GO annotations. 'TIDS' = for each end node, return the number of direct children found / total number of GO ids describing the list. 'none' = for each end node, return the number of direct children found.

probeType

type of input given to the function.Valid probe types include GO ids and any probes ids for which a BioC annotation package providing a mapping to GO is available. ontoCompare is expecting valid probe ids.

goType

help sort the data by type. If 'All' (default), all oligos are taken into account. 'BP' restricts information to Biological Process, 'CC' to Cellular Component, and 'MF' to Molecular Function.

plot

logical: if 'TRUE', results are output as a graph.

endnode

list of GO ids corresponding to end-nodes of interest.

beside

Logical. If 'TRUE', the bars of the barplot are portrayed as juxtaposed bars. See ?barplot for more details.

las

numeric: if las=2, the axis labels are displayed perpendicular to the axis. See ?par for more details.

legend.text

vector of text used to construct a legend for the plot. See ?barplot for more details.

objM

results from ontoCompare.

names.arg

Labels to use in ontoPlot.

...

extra layout parameters to be passed to ontoPlot.

Value

Returns the percentage of probes children of nodes contained in endnode. If 'plot' = TRUE, results are plotted as a pie chart or a bargraph.

Author(s)

Yee Hwa (Jean) Yang, Agnes Paquet

Examples

# Examples use the probeID dataset. For description type ?probeID.
# Not run

#library(GO.db)
#data(probeID)
#ontoCompare(affylist, probeType="hgu133a", plot=TRUE)
#res <- ontoCompare(operonlist["L1"], probeType="operon", method="TIDS")
#ontoPlot(res, cex=0.7)

Internal goTools functions

Description

Internal goTools functions

Details

These are not to be called by the user.


List of probe ids from Affymetrix hgu133a chip and Operon Version 2 Human oligos

Description

The probeID dataset consists of two lists of randomly chosen probe Ids. affylist contains 3 sets of ids from Affymetrix hgu133a. operonlist contains 2 sets of ids from Operon Version 2.

Usage

data(probeID)