Version: 1.8.0 Category: NEW FEATURES Text: GmapGenomes can be built from any file supported by rtracklayer (so 2bit now works, as well as fasta). Version: 1.8.0 Category: NEW FEATURES Text: Tally BAM files by codon given a set of transcript structures. This happens at the read level, i.e., a codon is observed within an individual read. Version: 1.8.0 Category: NEW FEATURES Text: Tally BAM files strand by XS tag (inferred strand of transcription, instead of strand of alignment). Version: 1.6.0 Category: NEW FEATURES Text: Add median distance from nearest end (MDFNE) statistics to output of variantSummary. Version: 1.6.0 Category: NEW FEATURES Text: Updated GSNAP, which is orders of magnitude faster than the previous version, brings many fixes and offers many new features. One new feature is the clip_overlap argument, which clips overlapping ends of read pairs (important for variant calling). Version: 1.6.0 Category: NEW FEATURES Text: Updated bam_tally, which is faster and includes support for counting in soft-clipped regions. Version: 1.6.0 Category: USER-VISIBLE CHANGES Text: Changes to tallyVariant statistics: drop the unique read position counts; renamed count.pos/count.neg to count.plus/count.minus (way better names) Version: 1.6.0 Category: USER-VISIBLE CHANGES Text: tallyVariants does a better job of carrying over the Seqinfo from the BAM file. Version: 1.4.0 Category: NEW FEATURES Text: Add desired_read_group to BamTallyParam; will limit tallies to that specific read group (useful for multi-amplicon sequencing, like Fluidigm) Version: 1.4.0 Category: NEW FEATURES Text: Add keep_ref_rows argument to variantSummary() for keeping rows for positions where no alt is detected (the rows where ref == alt). Version: 1.4.0 Category: NEW FEATURES Text: gsnap() will now output a GsnapOutputList when there are multiple input files Version: 1.4.0 Category: NEW FEATURES Text: Support 'terminal_threshold' and 'gmap_mode' parameters in GsnapParam, and use different defaults for DNA vs. RNA. This means a big improvement in alignment quality for DNA. Version: 1.4.0 Category: NEW FEATURES Text: GmapGenome now accepts a direct path to the genome as its first argument Version: 1.4.0 Category: USER-VISIBLE CHANGES Text: Renamed summarizeVariants to variantSummary Version: 1.4.0 Category: USER-VISIBLE CHANGES Text: The 'which' in GsnapParam is now a GenomicRanges instead of a RangesList Version: 1.4.0 Category: USER-VISIBLE CHANGES Text: Refactor bam_tally, so that bam_tally returns a TallyIIT object, which is then summarized via summarizeVariants; this allows computing tallies once and summarizing them in different ways (like maybe get the coverage). The summarizeVariants function yields a VRanges. Version: 1.4.0 Category: BUG FIXES Text: fix minimum quality cutoff check to >=, instead of > Version: 1.4.0 Category: BUG FIXES Text: fix asBam,GsnapOutput for when unique_only is TRUE Version: 1.4.0 Category: BUG FIXES Text: package created by makeGmapGenomePackage now have a GmapGenome with the correct name Version: 1.2.0 Category: NEW FEATURES Text: New method getSeq,GmapGenome retrieves sequence from a GmapGenome index. This also supports a coercion to DNAStringSet and thus easy export to FASTA via rtracklayer. Version: 1.2.0 Category: NEW FEATURES Text: bam_tally gains an ignore_duplicates argument for ignoring BAM records flagged as PCR/optical duplicates. Version: 1.2.0 Category: NEW FEATURES Text: Read position mean and variance are now output by bam_tally. Version: 1.2.0 Category: USER-VISIBLE CHANGES Text: GMAP has been updated to the July '12 version (yes, this is old). Version: 1.2.0 Category: USER-VISIBLE CHANGES Text: GSTRUCT (bamtally) updated to trunk as of 3/22/13. Version: 1.2.0 Category: BUG FIXES Text: asBam,GsnapOutput now actually works. Version: 1.0.0 Category: Initial release Text: (start date: 12 September, 2012)