Package: genomicInstability
Version: 1.19.0
Date: 2020-02-21
Title: Genomic Instability estimation for scRNA-Seq
Authors@R: c(person("Mariano", "Alvarez", role=c("aut", "cre"),
           email="reef103@gmail.com"),
           person("Pasquale", "Laise", role="aut",
           email="plaise@darwinhealth.com"),
           person("DarwinHealth", role="cph"))
Depends: R (>= 4.1.0), checkmate
Suggests: SingleCellExperiment, ExperimentHub, pROC
Imports: mixtools, SummarizedExperiment
Description: This package contain functions to run genomic instability
        analysis (GIA) from scRNA-Seq data. GIA estimates the
        association between gene expression and genomic location of the
        coding genes. It uses the aREA algorithm to quantify the
        enrichment of sets of contiguous genes (loci-blocks) on the
        gene expression profiles and estimates the Genomic Instability
        Score (GIS) for each analyzed cell.
License: file LICENSE
biocViews: SystemsBiology, GeneExpression, SingleCell
BiocType: Software
URL: https://github.com/DarwinHealth/genomicInstability
BugReports: https://github.com/DarwinHealth/genomicInstability
Encoding: UTF-8
ARoxygenNote: 7.1.1
RoxygenNote: 7.1.1
Config/pak/sysreqs: cmake make libicu-dev libuv1-dev libssl-dev
        zlib1g-dev
Repository: https://bioc.r-universe.dev
Date/Publication: 2026-04-28 12:56:43 UTC
RemoteUrl: https://github.com/bioc/genomicInstability
RemoteRef: HEAD
RemoteSha: 190734f5482674ffd9bb2c54c99c6d920861058e
NeedsCompilation: no
Packaged: 2026-07-04 09:04:53 UTC; root
Author: Mariano Alvarez [aut, cre],
  Pasquale Laise [aut],
  DarwinHealth [cph]
Maintainer: Mariano Alvarez <reef103@gmail.com>